PB0149

DATABASE

Click here to access PB0149 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0149	Q6UX07	Dehydrogenase/reductase SDR family member 13	DHRS13	SDR7C5	Homo_sapiens	Putative oxidoreductase.

Domains	Gene Ontology
PF00106 (adh_short)	GO:0016491 (enables) oxidoreductase activity GO:0052650 (enables) NADP-retinol dehydrogenase activity GO:0042572 (involved in) retinol metabolic process GO:0042574 (involved in) retinal metabolic process GO:0005743 (is active in) mitochondrial inner membrane GO:0005576 (located in) extracellular region GO:0016020 (located in) membrane

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|Q6UX07|DHR13_HUMAN Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens OX=9606 GN=DHRS13 PE=2 SV=1 MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRG ARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILI HNAGISSCGRTREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDF KRLDRPVVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVP GWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAA HRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLS KMTHRIQAKVEPEIQLS >sp|Q6UX07-2|DHR13_HUMAN Isoform 2 of Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens OX=9606 GN=DHRS13 MTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFL SSEPRLDILIHNAGISSCGRTREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVAS AAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPV NSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEV PPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPY PSPQSSPDLSKMTHRIQAKVEPEIQLS >sp|Q6UX07-3|DHR13_HUMAN Isoform 3 of Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens OX=9606 GN=DHRS13 MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGISSCGRTREAFNLLLRV NHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTK LANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGG AQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEP DEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPEIQLS >tr|F1R2W1|F1R2W1_DANRE Dehydrogenase/reductase (SDR family) member 13a, duplicate 3 OS=Danio rerio OX=7955 GN=dhrs13a.3 PE=1 SV=1 MSVLLSVLVGVLAAYVLIYYCLFKGARYKGNATLNGKTAIVTGSNTGIGKTTALDLARRG ARVILACRNQERAEAAVYDIRKESGNSEVLYMHLDLASLQSVRDFAETFLKTEPRLDLLI NNAGLIASGRTEDGFGMAFGVNHLGHFLLTLLLLDRLKQSENSRVVNVSALLHRLGSLDF NLLNTQKDLVTGQSYWHAIKAYCHSKLCNVLFTRELANRLEGTSVTCYCLHPGVISTEIG RYMGPLQKLLCLPMSKLFFLDPEAGAQTTLYCALQEGLEPLSGRYFSSCALQEVGALGRD DALARKLWDVSERLCGLS
Selected proteins from model organisms >sp|Q6UX07|DHR13_HUMAN Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens OX=9606 GN=DHRS13 PE=2 SV=1 MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRG ARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILI HNAGISSCGRTREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDF KRLDRPVVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVP GWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAA HRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLS KMTHRIQAKVEPEIQLS >sp|Q6UX07-2|DHR13_HUMAN Isoform 2 of Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens OX=9606 GN=DHRS13 MTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFL SSEPRLDILIHNAGISSCGRTREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVAS AAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPV NSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEV PPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPY PSPQSSPDLSKMTHRIQAKVEPEIQLS >sp|Q6UX07-3|DHR13_HUMAN Isoform 3 of Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens OX=9606 GN=DHRS13 MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGISSCGRTREAFNLLLRV NHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTK LANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGG AQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEP DEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPEIQLS >tr|F1R2W1|F1R2W1_DANRE Dehydrogenase/reductase (SDR family) member 13a, duplicate 3 OS=Danio rerio OX=7955 GN=dhrs13a.3 PE=1 SV=1 MSVLLSVLVGVLAAYVLIYYCLFKGARYKGNATLNGKTAIVTGSNTGIGKTTALDLARRG ARVILACRNQERAEAAVYDIRKESGNSEVLYMHLDLASLQSVRDFAETFLKTEPRLDLLI NNAGLIASGRTEDGFGMAFGVNHLGHFLLTLLLLDRLKQSENSRVVNVSALLHRLGSLDF NLLNTQKDLVTGQSYWHAIKAYCHSKLCNVLFTRELANRLEGTSVTCYCLHPGVISTEIG RYMGPLQKLLCLPMSKLFFLDPEAGAQTTLYCALQEGLEPLSGRYFSSCALQEVGALGRD DALARKLWDVSERLCGLS >NP_899109.2 dehydrogenase/reductase SDR family member 13 precursor [Mus musculus] MEMLLLGAGLLLGAYVLVYYNLVKAPSCGGIGSLRGRTVVVTGANSGIGKMTALELARRGARVVLACRSR ERGEAAAFDLRQESGNNEVIFMALDLASLASVQAFATAFLSSEPRLDVLIHNAGISSCGRTRETFNLLLR VNHVGPFLLTHLLLPRLRSCAPSRVVIVSSAAHRRGRLDFTRLDCPVVGWQQELRAYADSKLANVLFARE LATQLEGTGVTCYAAHPGPVNSELFLRHLPGWLRPILRPLAWLVLRAPQGGAQTPLYCALQEGIEPLSGR YFANCHVEEVSPAARDDQAAQRLWKATKKLAGLAPGDDDDDPDEEPEPEDPRAPSSQSAPSPEKTTVSGP SHSYQGSQDLSKLTQRRIQVKDEPTP >XP_038943561.1 dehydrogenase/reductase SDR family member 13 [Rattus norvegicus] METLLLGAGLLLGAYVLVYYNLVKAPPCGGIGSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSR ERGEAAAFDLRQESGNNEVIFMALDLASLTSVQAFATAFLSSEPRLDILIHNAGISSCGRTRETFNLLLR VNHVGPFLLTHLLLPRLRSCAPSRVVIVSSAAHRRGRLDFTRLDCPVVGWQQELRAYADSKLANVLFARE LATQLEGTGVTCYAAHPGPVNSELFLRHLPGWLRPILRPLAWLVLRAPQGGAQTPLYCALQEGIEPLSGR YFANCHVEEVSAAARDDQAAHRLWKVTKKLAGLGPEDDPDTDDEQEPRDPRAPSSLSAPSPEKTTISGPS RSYQGSQDLSKVTQRRIHVKDEPTP >NP_001069155.1 dehydrogenase/reductase SDR family member 13 precursor [Bos taurus] MEALLLGVGLLLGAYVLVYYNLVKAPPCRGLASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSR ERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREPFNLLLR VNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRGRLDFTRLDHPVVGWQQELRAYANSKLANVLFARE LATQLEGTGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGR YFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAESDEDSQPEDPGTPSSPSSPHPEEPTVSELY PSPQSSTDRSTVTCRIPVKAELEPQAC >XP_002827235.1 dehydrogenase/reductase SDR family member 13 [Pongo abelii] MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSR ERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREAFNLLLR VNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHRRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARE LANQLEGTGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGR YFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPFSLSTPHPEEPTVSQPY PSPQSSPDLSKMTHRIQAKVEPETQLS >XP_020923154.1 dehydrogenase/reductase SDR family member 13 [Sus scrofa] MEALLLGVGLLLGAYVLVYYNLVKAPPCRGIASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSR ERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREPFNLLLR VNHVGPFLLTHLLLPRLKTCAPSRVVVVSSAAHRRGRLDFTRLDRPVVGWRQELRAYADSKLANVLFTRE LATQLEGTGVTCYAAHPGPVNSELFLRHVPRWLRPLLCPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGR YFANCHVEEVPPAARDDRAAHRLWEASKRLAGLEPGEDAESDEEPQPVDPGVPSSLSSPHPEEPAASEPY TSPQSSPDLSKVTRRIPVKAEPEPQAS >XP_003639330.1 dehydrogenase/reductase SDR family member 13 [Canis lupus familiaris] MEALLLGAGLLLGAYVLIYYNLVKAPPCGGIASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSR ERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTHKPFNLLLR VNHIGPFLLTHLLLPRLKTCAPSRVVVVSSAAHRRGRLDFTRLDRPVVGWQQELRAYADSKLANVLFARE LATQLEGTGVTCYAAHPGPVNSELFLRHVPGWLCPLLRPLAWLMLRAPRGGAQTPLYCALQEGIEPLSGR YFANCHVEEVPPAARDDRAAHQLWEASKRLAGLGPGKDAEADEDSQPEDPRTPSSPSSPHPEEPTVSEPC PTSQSSQDLPKVTRRIQVQTEPEPCIS >XP_003642478.4 dehydrogenase/reductase SDR family member 13 isoform X1 [Gallus gallus] MGWWLLVVGLLLCVLLRFALRSSTPPFALHALHGRTAVVTGGSSGIGEAVARELARCGARVVLATRDALR GEEAAWRIRRDTGNPEVLFMPLDLSSLHSVHAFATAFLQQEPHLHLLINNAGVSAGGTTEDGFSLPFQVN HLGHFLLTQLLLQRLQSSAPSRVVIVASSAHCAGRLRMAELGCPPPGPFAAFQDYCDSKLANVLHARQLA ARLQGTGVTAYAVHPGFVNTRLFRHAPLWLQLLWTPLSRFCFRSAAEGARTVLFCATQDGLEPFSGCYFA DCRPLQPWAQGRDDAAARELWDRSERLLGLQPSLCTPVE >XP_034798074.1 dehydrogenase/reductase SDR family member 13 [Pan paniscus] MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQ ERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREAFNLLLR VNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARE LANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGR YFANCHVEEVPPAARDDRAAHRLWEASKMLAGLGPGEDAEPNEDPQSEDSEAPSSLSTPHPEEPTVSQPY PSPQSSPDLSKMTHRIQAKVEPEIQLS >XP_019673010.1 dehydrogenase/reductase SDR family member 13 isoform X1 [Felis catus] MEALLLGAGLLLGAYVLVYYNLVKAPPCGGIASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSR ERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAAPAPGISSCGRTHEPFN LLLRVNHIGPFLLTHLLLPRLKTCAPSRVVVVSSAAHRRGHLDFTRLDRPVVGWQQELRAYADSKLANVL FARELATQLEGTGVTCYAAHPGPVNSELFLRHVPGWLSPLLRPLAWLVLRTPRGGAQTPLYCALQEGIEP LSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGQDAGPDEDPQPEDPGTPSSRSSPLSEEPTV SEPHPIPHNSPDLSKVTHRIQVKTEPEP >XP_014954034.2 dehydrogenase/reductase SDR family member 13 [Ovis aries] MEALLLGVGLLLGAYVLVYYNLVKAPPCRGLASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSR ERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREPFNLLLR VNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRGRLDFTRLDRPVVGWRQELRAYADSKLANVLFARE LATQLEGTGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGR YFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAESDEDSQPEDPGTPSSPSSPHPEEPTASELY PSPQSSTDWSTVTRRIPVKAELEPQAC >XP_018883279.1 dehydrogenase/reductase SDR family member 13 [Gorilla gorilla gorilla] MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQ ERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREAFNLLLR VNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARE LANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGR YFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPY PSPQSSPDLSKMTHRIQAKVEPETQLS >XP_017919816.1 PREDICTED: dehydrogenase/reductase SDR family member 13 [Capra hircus] MEALLLGVGLLLGAYVLVYYNLVKAPPCRGLASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSR ERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREPFNLLLR VNHIGPFLLTHLLLPRLKRSAPSRVVVVSSAAHRRGRLDFTRLDRPVVGWRQELRAYADSKLANVLFARE LATQLEGTGVTCYAAHPGPVNSDLFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGR YFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAESDEDSQPEDPGTPSSPSSPHPEEPTASELY PSPQSSTTDWSTVTRRIPVKAELEPQAC >XP_025070399.1 dehydrogenase/reductase SDR family member 13 [Alligator sinensis] MSLDLASLDSVRAFAETFLRSERRLDLLVLNAGEARGSRLGTKGSQNRXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXCAPSRVVVVASNAHRSGRIDFERLGRPVEGVLQNFQAYCDSKLANILFAR ELAGRLEGTGVTCYALHPGVVNTALFSFVPAWLRLLFMPFSWLFFQDAVSGAQTSIHCATQEGIEAFSGR FFADCRPQEPRPRARDDTVARKLWEVSERMVGLAA >XP_016787649.1 dehydrogenase/reductase SDR family member 13 [Pan troglodytes] MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQ ERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREAFNLLLR VNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARE LANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGR YFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPY PSPQSSPDLSKMTHRIQAKVEPEIQLS >XP_019477415.2 dehydrogenase/reductase SDR family member 13 [Meleagris gallopavo] MGWWLLGVGLLLCLLLRFTLRSPAPLLALPALRGRTAIVTGGSSGIGEAVARELARCGARVVLATRNALR GEEAAWRIRRDTGNPEVLFMPLDLSSLHSVHAFATAFLQQEPHLHLLINNAGVSAGGTTEDGFSLPFQVN YLGHFLLTRLLLQRLQSSAPSRVIIVASSAHCAGRLRMAELGRPPPGPFAAFQDYCDSKLANVLHARQLA ARLQGTGVTSYAVHPGMGSSVPSGLLVACLHEARLHLEYPLARCSFAWCSLCMQHLSVLCIFYTVHLLHS FPLHDASHCAVRGAPLCAVHPLHSSPSARHPFACHIPLCDASLCTPHPFAQPSLCTPHPFAHHIPLHSHP FV >XP_014466095.2 PREDICTED: dehydrogenase/reductase SDR family member 13 [Alligator mississippiensis] MSLDLASLDSVRAFAETFLRCEPRLDLLVLNAGIASGGRRSDGCNLVFQVNHLGHFLLTQLLLERLKHCA PSRVVVVASSAHRSGRIDFERLGRPVEGVLQNFQAYCDSKLANILFARELAGRLEGTGVTCYALHPGVVN TALFSFVPAWLWPLFVPFSWLFFRDAMSGAQTSIHCATQEGIEALSGRYFADCRPQEPRPRARDDTVARK LWEVSERMVGLAA >XP_040194468.1 dehydrogenase/reductase SDR family member 13 [Rana temporaria] MAPVLLIPAIVVALYILIYYNFIQGRQCKSEQRLRGRTVIVTGGNVGIGKMTALDMAKRGARVILACRNK ETAEAAAHDIRRLSGNNEVLFMKLDLASIASIRSFCKTFLDSEPRLDILINNAGLTAKGKTEDGFNMVFG VNHLGHFLLTHLLLDRLKQCTPSRIVVLASNAHKMGRINFKNLNPAGETWLEIFRTYSDSKLANVLFARE LANRLQGTEVTCYAVHPGVVHTNLGRNFPSWLQVPLFPFLWLFLRTSMDGAQTSIYCSVEEDIEQYSGRY FNNCRVEQVPPHARDDAVAKKLWEVSEDLLGLNK >XP_793866.1 retinol dehydrogenase 12 [Strongylocentrotus purpuratus] MISLSTLSLERVPDFGQRGPGDLEWTTIALMMVVLVVGLYYYVVKVADRCSCPKRLDGKTVIVTGANTGIGKETARDLAR RGARVILACRDAVRGREAEKDIRMSTGNDDVIFMKLNLASFDSIRHFAQEFNNTEERLDILVNNAGVINDGSLRTEEGHE LVFGVNHLGHFLLTNILLDKLQKCAPSRVINVSSDAYMFGKLDLERLSVNDGRVKSYARSKLANVLFTRQLADKMAGTGV VSFSLHPGSVNTEIKRNWAGWLRALAPLISFFFLKSVKAGAQTSIHCAVSDDILDQSGEFFKGCQVQKLSRTAQDQDLAQ RLWDVSLEMTGLQSS >XP_038061579.1 retinol dehydrogenase 12-like [Patiria miniata] MLELTSVTLGQWKLWDGPQYHGFCLGVCVSVALVMCVSVYYYFVKVADRCTCTTRLDGKTVIITGANTGIGKETAVDLAH RGARVILACRSESRGIQAEREIREQTGNSHVHFMRLDLASQESVKEFAQEFCNREDRLDILINNAGVINDGSAQTAEGYE LSFGVNHLGHFLLTNLLLAKLQSSSPSRVINVSSDAYQLGRLGFQDGAGLLCGKEGRVKLYARSKLANLLFTHELAKTME GTDVAIFALHPGSINTDIKRNWAWWLRTLSPLISFLFLKTTTEGAQTTIHCAVAEDLQKHSGKYFKGCRVQKVAPMARDD KLSRKLWRVSLQMTGLTNT >XP_031553920.1 retinol dehydrogenase 11-like [Actinia tenebrosa] MASIPVAVAVGVGGALGLYFARQYFKGGEFKSTRRLDGKTVIITGANTGIGKETAIDLAKRGARVIIACRSPDRGKQALK EIQEQSNSQQVYLEKLDLASLKSVREFAEKIKKNEPRLDILINNAGVMMCPYMTTEDGFELQIGVNHLGHFLLTNLLLDL LKKSAPSRVINLSSLGHTMTSRFKFQNMNNEKTYGKVEAYAQSKLANILFTKELARRLEGTGVTTYAVHPGTVETELDRH TFFSSSILGAPFRPIRWLTCKTPIQGAQTSLYCAVSEDLEGVTGRYYADCAETPSSEASKNEEDAKTLWDVSVELVGL >XP_039255571.1 retinol dehydrogenase 13-like [Styela clava] MAEASSVKNGSVLKDIRMDGKTVLITGANTGIGYETAKDLSSRGAKVIMAGRDAGKVEKAMKEIKSCDLKANLVGVELDL ASMESIRKCADKIMETEAKLDVLINNAGIMSCPQWKTKDGFEMQLGVNHIGHFLFTNLLLDLVKKSSPSRIVILSSSGHT RGRMNWDDIMSEKKYNPFVVYCQSKLANILFARELSRKLEGTGVTCNSVHPGLVKTELGRHFMNKEGTWNTIKYYLVFPF VKMIFKTPEQGAQTSIYCAVAPELNQVSGKYFADCKIEEEAPAAKNDEDAKRLWELSLEWTGLKSK >AAK93548.1 SD07613p [Drosophila melanogaster] MCIFIDCLLSPLIMWPATIGVGIYFLKEYMQGGKFTKDTDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRC EKARKDIIKETNNQNIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNAGVMRCPKTLTKDGYELQLGVNHIGHFLLTN LLLDVLKNSAPSRIVVVSSLAHARGSINVADLNSEKSYDEGLAYSQSKLANVLFTRELAKRLEGSGVTVNALHPGVVDTE LARNWAFFQTNLVKFFLKPMIWPLLKTPKSGAQTSIYAALDPELKNISGLYFSDCKPKPVAPGALDDKVAKFLWAESEKW TGLDKLEANN >CAE1254144.1 RDH12 [Sepia pharaonis] MIGLILAGFLIVLFIIICWRHSWGVCTSKTDLTGKTVIITGCNTGIGYYVALDLAFRNARIIMACRNAEKANAAKEKIIA ETGNKQIVFQQVNLSSLQSVRQFAERIIKEESRLDILINNAGIMHSNSLLTEDGLTTIYATNHFAPFLLTNLLLDLLQSS APSRVINVSSHGHKIGSIRFENMKCPMLDDGNRTYANTKLANVLFTRELARRTEGKGVSTFSVHPGFCDTELFRFMPSLV QALMTRYPLMKTAKEGAQTILHCALSEGIESTSGEYYSDCKVSSTSAKGRDMAVAKKLWEVL >XP_395899.2 retinol dehydrogenase 13 [Apis mellifera] MFSRIAKPFYLYSAGISIIGGAYLLKDYLGGNLYDNTDKLNDKIVIVTGANTGIGREIARDLAKREAKVIMACRDMDKCE IARRDIVIESQNKFVYCRECDLASQASIRDFVKQFKQEHNNLHILINNAGVMRCPKKHTKEGIEMQFGVNHLGHFLLTNL LLDVLKSSAPSRIINVSSSAHKRGKIKLDDLNSEKNYEPGEAYAQSKLANILFTKELANKLKGTGVTVNAVHPGIVRTEI MRHMGIYQYYFGRLLADLLTWIFIKTPLKGAQPILFVAIDPSLNDVTGEYFVNNKIADVSNEAKNDQIARWLWIVSEKWT KLNYM >NP_506570.1 DeHydrogenases, Short chain [Caenorhabditis elegans] MDGADAEEHGGFLFFVLASSVVFIVLFFTRRYFKGGQFNERVSAKGLVAVVTGSNCGIGFETVRELNLRKADVYMLCRSE EKANEAKRMLVRQGCDATRLHFIECDLTDFESVRRAAKETLESTDTIDILINNAGIMFQSKHEQTKDGHEKTWQSNHLGP FLLTELFLPAVKKSSYARIINVSSRIHLKSEKINLATVDDKKSFGMMKSYRQSKLANVMHARALTKELRKDGAEHVTVNS LHPGVVNTELARNTILNTPGIKQITAVFRWFLMKTSRDGAQTSIFLALGKKIGGISGKYFADCKLTQENPLALDDQACQD LYNYSLECTGLAK >KAB0360396.1 hypothetical protein FD754_004552 [Muntiacus muntjak] MEALLLGVGLLLGAYVLVYYNLVKAPPCHGLASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDL RQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREPFNLLLRVNHIGPFLLTHLLLPRLKTS APSRVVVVSSAAHRRGRLDFTRLDRPVVGWRQELRAYADSKLANVLFARELATQLEGSGVTCYAAHPGPVNSELFLRHVP GWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAE SDEDSQPEDPGTPSAPSSPHPEEPTASELYPSPQNSTDRSTVMRRIPVKAELEPQAC >XP_043759159.1 dehydrogenase/reductase SDR family member 13 isoform X2 [Cervus elaphus] MEALLLGVGLLLGAYVLVYYNLVKAPPCRGLASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDL RQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREPFNLLLRVNHIGPFLLTHLLLPRLKTS APSRVVVVSSAAHRRGRLDFTRLDRPVVGWRQELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHVP GWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAE SDEDSQPEDPGTPSSPSSPHPEEPTASELYPSPQNSTDRSTVTRRIPVKAELEPQAC >KAB0367217.1 hypothetical protein FD755_020541 [Muntiacus reevesi] MEALLLGVGLLLGAYVLVYYNLVKAPPCHGLASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDL RQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREPFNLLLRVNHIGPFLLTHLLLPRLKTS APSRVVVVSSAAHRRGRLDFTRLDRPVVGWRQELRAYADSKLANVLFARELATQLEGSGVTCYAAHPGPVNSELFLRHVP GWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAE SDEDSQPEDPGTPSSPSSPHPEEPTASELYPSPQNSTDRSTVTRRIPVKAELEPQAC >XP_043335380.1 dehydrogenase/reductase SDR family member 13 isoform X2 [Cervus canadensis] MEALLLGVGLLLGAYVLVYYNLVKAPPCRGLASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDL RQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREPFNLLLRVNHIGPFLLTHLLLPRLKTS APSRVVVVSSAAHRRGRLNFTRLDRPVVGWRQELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHVP GWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAE SDEDSQPEDPGTPSSPSSPHPEEPTASELYPSPQNSTDRSTVTRRIPVKAELEPQAC >KAF4012156.1 hypothetical protein G4228_003164 [Cervus hanglu yarkandensis] MEALLLGVGLLLGAYVLVYYNLVKAPPCRGLASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDL RQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREPFNLLLRVNHIGPFLLTHLLLPRLKTS APSRVVVVSSAAHRRGRLDFTRLDRPVVGWRQELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHVP GWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAE SDEDSQPVDPGTPSSPSSPHPEEPTASELYPSPQNSTDRSTVTRRIPVKAELEPQAC >XP_020767410.1 dehydrogenase/reductase SDR family member 13-like [Odocoileus virginianus texanus] MEALLLGVGLLLGAYVLVYYNLVKAPPCRGLASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDL RQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREPFNLLLRVNHIGPFLLTHLLLPRLKTS APSRVVVVSSAAHRRGRLDFTRLDRPVVGWQQELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGEVRLSGCSASFL FPLSHPRPLPCSPSLSLSHRTSEQEGSLVQGEARSLLILKPGSPCLGFSSHTTSSDADGWVRHGNEEGLGSHPKEPSA >NP_001087976.1 dehydrogenase/reductase (SDR family) member 13 L homeolog [Xenopus laevis] MVPVILLLGVGVGAYVLIYFNLIRGRQCRSDASLKGKTVIVTGANIGIGKMTALDMARRGARVILACRVKETGEAAAYDI RQLSGNNQVLFMNLNLSSLESVRSFCRAFLSSEPRLDILINNAGFSGPGKTAEGYNIVFGINHLGHFLLTSLLLDRLKQS TPSRIVALASYAHEWGKIDFNKISVPSDHIKDILQSYCDSKLCNVLFARELANRLEGTGVTCYSVHPGTVHTNLVRSLPN WIKACIKPFTWLFLRTPMDGAQTSIYCAVQEGIEMYTGRYFDNCQVRQVKPHARDDAVAKKLWEVSERMTGLAS >XP_030262215.1 dehydrogenase/reductase SDR family member 13-like isoform X2 [Sparus aurata] MSVLLSLVAGAVSFYVIVYYGVFGGSRCSSSVKLKGKTAIVTGSNTGIGKATALDLAKRGARVILACRNKEKAEAAVFDI RRESGNNQVMFMLLDLGSLKSVRSFAENFLKSEPRLDILINNAGIMGPGHTEDGFGMAFGVNHLGHFLLTNLLLERLQQC GPSRVVTVAALLHRFGNIDFPPLASRNKLVSGQSTWHNFRAYCNSKLCNVLFARELANRLEGTSVTSYSLHPGVVYTELC RSMSLWQLLLMIPFAKLFFLGPEGGSQTTLYCALQEGIEPLSGRYFSNCALQQVGAIGRDDALAKKLWEVSERLTSVSQE TES >XP_004075984.2 dehydrogenase/reductase SDR family member 13 isoform X1 [Oryzias latipes] MRPSAVSQKPKTTQEEEVALPSNMLLCVVAGAVSFYLLIYYGVFRVQRCTSSVRLKGKTVIVTGSNTGIGKSTALALARR GARVILACRSKERGTAAAFDIRKESGNNQVVFMPLDLADFRSVHSFAETFLETEPRLDILINNAGIMGPGRTVDGFGMAF GVNHLGHFLLTNLLLERLKQCGPSRVVTVSALLHHLGRIDFALLGSTKDLVSGQSTWQNFQAYCNSKLCNVLFTRELANH LEGTGVTCFTLHPGVVYTELCRNMSWWQQLLLIPVAKLFFLDTDGGSQTTLHCSLQEGIESFSGRYFSNCRVQNMGVKGR DDSLAQKLWEVSERLTGFHTRVSQHAERA >XP_015807550.1 PREDICTED: dehydrogenase/reductase SDR family member 13-like [Nothobranchius furzeri] MSIILLAVGVFIGAAFIYHHIVVKGKKCTSKAELHGKTVIVTGSNTGIGRTTAINLARRGARVILACRCKQRGEAAQEDI RRESGSNQVVFMQLDLGSLESVRSFAETFLKSEPRLDLLINNAGICMQGRTKDGFGLMFGVNHLGHFLLTNLLLERLKES APSRIVNVSSMAHNFGKIDFDSLNTHKCLGLGTSSVRVFQIYCDSKLCNVLFNHELAKRLQGTRVTCYALHPGAISSELG RNTSSLLHVLLKPVTVLFFKNTVQGCQTTLHCALQEGIEPLSGRYFSNCTVRELFAKAKDDAAAKKLWEISERLCGLV >XP_002719556.1 PREDICTED: retinol dehydrogenase 12 [Oryctolagus cuniculus] MLVVLGLLTCFLSVLYVTAPSIRKFFAGGVCQTNIQLPGKVVVITGANTGIGKETARELARRGARVYIACRDILKGESAA SEIRADTKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMLCPQSKTADGFETHLGVNHLGHFLLTYLLLE RLKESAPARVVNLASVAHYVGKIRFHDLQGEKYYCSSFAYCQSKLANVLFTRELAKRLQGTGVTTYAVHPGIVSSELVRH SFLLCLLWRLFSVFVKSAREGAQTSLHCALAEGLEPLSGKYFSDCKRTWVSPRARNNKTAQRLWNVSCELLGIQWE
Mafft alignment of selected proteins >sp|Q6UX07|DHR13_HUMAN Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens OX=9606 GN=DHRS13 PE=2 SV=1 -----------------------MEALLLGAGLLLGAYVLVYYNLV----KAPPCGGMGN LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCR-GRLDFKRLD RPV-----VGWRQELRAYADTKLANVLFARELANQLEATG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASKRLAGLGPGEDAE-PDEDPQSED SEAPSSLSTPHPEEPTVSQPYPSPQSS-PDLSKMTH-RIQAKVEPEIQLS >sp|Q6UX07-2|DHR13_HUMAN Isoform 2 of Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens OX=9606 GN=DHRS13 ------------------------------------------------------------ -----------------MTALELARRGARVVLACRSQERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCR-GRLDFKRLD RPV-----VGWRQELRAYADTKLANVLFARELANQLEATG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASKRLAGLGPGEDAE-PDEDPQSED SEAPSSLSTPHPEEPTVSQPYPSPQSS-PDLSKMTH-RIQAKVEPEIQLS >sp|Q6UX07-3|DHR13_HUMAN Isoform 3 of Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens OX=9606 GN=DHRS13 -----------------------MEALLLGAGLLLGAYVLVYYNLV----KAPPCGGMGN LRGRTAVVT--------------------------------------------------- -----------------------------------GIS-SCGR----------------- -----TREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCR-GRLDFKRLD RPV-----VGWRQELRAYADTKLANVLFARELANQLEATG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASKRLAGLGPGEDAE-PDEDPQSED SEAPSSLSTPHPEEPTVSQPYPSPQSS-PDLSKMTH-RIQAKVEPEIQLS >tr|F1R2W1|F1R2W1_DANRE Dehydrogenase/reductase (SDR family) member 13a, duplicate 3 OS=Danio rerio OX=7955 GN=dhrs13a.3 PE=1 SV=1 -----------------------MSVLLSVLVGVLAAYVLIYYCLF----KGARYKGNAT LNGKTAIVTGSNTGIGKTTALDLARRGARVILACRNQERAEAAVYD-IRKESGNSEVLYM HLDLASLQSVRDFAETFLKTEPRLDLLINNA----GLI-ASGR----------------- -----TEDGFGMAFGVNHLGHFLLTLLLLDRLKQSENSRVVNVSALLHRL-GSLDFNLLN TQKDLVTGQSYWHAIKAYCHSKLCNVLFTRELANRLEGTS---VTCYCLHPGVIST---- ---------EIG-RYMGP-------LQKLLCLPMSKLFFLDPEAGAQT-----TLYCALQ EGLEPLSGRYFSSCALQEVGALGRDDALAR-KLWDVSERLCGLS---------------- -------------------------------------------------- >NP_899109.2 dehydrogenase/reductase SDR family member 13 precursor [Mus musculus] -----------------------MEMLLLGAGLLLGAYVLVYYNLV----KAPSCGGIGS LRGRTVVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVQAFATAFLSSEPRLDVLIHNA----GIS-SCGR----------------- -----TRETFNLLLRVNHVGPFLLTHLLLPRLRSCAPSRVVIVSSAAHRR-GRLDFTRLD CPV-----VGWQQELRAYADSKLANVLFARELATQLEGTG---VTCYAAHPGPVNS---- ---------ELFLRHLPG-------WLRPILRPLAWLVLRAPQGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVSPAARDDQAAQ-RLWKATKKLAGLAPGDDDDDPDEEPEPED PRAPSSQSAPSPEKTTVSGPSHSYQGS-QDLSKLTQRRIQVKDEPTP--- >XP_038943561.1 dehydrogenase/reductase SDR family member 13 [Rattus norvegicus] -----------------------METLLLGAGLLLGAYVLVYYNLV----KAPPCGGIGS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLTSVQAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TRETFNLLLRVNHVGPFLLTHLLLPRLRSCAPSRVVIVSSAAHRR-GRLDFTRLD CPV-----VGWQQELRAYADSKLANVLFARELATQLEGTG---VTCYAAHPGPVNS---- ---------ELFLRHLPG-------WLRPILRPLAWLVLRAPQGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVSAAARDDQAAH-RLWKVTKKLAGLGPEDDPD-TDDEQEPRD PRAPSSLSAPSPEKTTISGPSRSYQGS-QDLSKVTQRRIHVKDEPTP--- >NP_001069155.1 dehydrogenase/reductase SDR family member 13 precursor [Bos taurus] -----------------------MEALLLGVGLLLGAYVLVYYNLV----KAPPCRGLAS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRR-GRLDFTRLD HPV-----VGWQQELRAYANSKLANVLFARELATQLEGTG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASRKLAGLGPGEDAE-SDEDSQPED PGTPSSPSSPHPEEPTVSELYPSPQSS-TDRSTVTC-RIPVKAELEPQAC >XP_002827235.1 dehydrogenase/reductase SDR family member 13 [Pongo abelii] -----------------------MEALLLGAGLLLGAYVLVYYNLV----KAPPCGGMGN LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHRR-GRLDFKRLD RPV-----VGWRQELRAYADTKLANVLFARELANQLEGTG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASKRLAGLGPGEDAE-PDEDPQSED SEAPFSLSTPHPEEPTVSQPYPSPQSS-PDLSKMTH-RIQAKVEPETQLS >XP_020923154.1 dehydrogenase/reductase SDR family member 13 [Sus scrofa] -----------------------MEALLLGVGLLLGAYVLVYYNLV----KAPPCRGIAS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREPFNLLLRVNHVGPFLLTHLLLPRLKTCAPSRVVVVSSAAHRR-GRLDFTRLD RPV-----VGWRQELRAYADSKLANVLFTRELATQLEGTG---VTCYAAHPGPVNS---- ---------ELFLRHVPR-------WLRPLLCPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASKRLAGLEPGEDAE-SDEEPQPVD PGVPSSLSSPHPEEPAASEPYTSPQSS-PDLSKVTR-RIPVKAEPEPQAS >XP_003639330.1 dehydrogenase/reductase SDR family member 13 [Canis lupus familiaris] -----------------------MEALLLGAGLLLGAYVLIYYNLV----KAPPCGGIAS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----THKPFNLLLRVNHIGPFLLTHLLLPRLKTCAPSRVVVVSSAAHRR-GRLDFTRLD RPV-----VGWQQELRAYADSKLANVLFARELATQLEGTG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLCPLLRPLAWLMLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-QLWEASKRLAGLGPGKDAE-ADEDSQPED PRTPSSPSSPHPEEPTVSEPCPTSQSS-QDLPKVTR-RIQVQTEPEPCIS >XP_003642478.4 dehydrogenase/reductase SDR family member 13 isoform X1 [Gallus gallus] -----------------------MGWWLLVVGLLL--CVLLRFALR----SSTPPFALHA LHGRTAVVTGGSSGIGEAVARELARCGARVVLATRDALRGEEAAWR-IRRDTGNPEVLFM PLDLSSLHSVHAFATAFLQQEPHLHLLINNA----GVS-AGGT----------------- -----TEDGFSLPFQVNHLGHFLLTQLLLQRLQSSAPSRVVIVASSAHCA-GRLRMAELG CPP-----PGPFAAFQDYCDSKLANVLHARQLAARLQGTG---VTAYAVHPGFVNT---- ---------RLF-RHAPL-------WLQLLWTPLSRFCFRSAAEGART-----VLFCATQ DGLEPFSGCYFADCRPLQPWAQGRDDAAAR-ELWDRSERLLGLQP--------------- -----SLCTPVE-------------------------------------- >XP_034798074.1 dehydrogenase/reductase SDR family member 13 [Pan paniscus] -----------------------MEALLLGAGLLLGAYVLVYYNLV----KAPPCGGMGN LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCR-GRLDFKRLD RPV-----VGWRQELRAYADTKLANVLFARELANQLEATG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASKMLAGLGPGEDAE-PNEDPQSED SEAPSSLSTPHPEEPTVSQPYPSPQSS-PDLSKMTH-RIQAKVEPEIQLS >XP_019673010.1 dehydrogenase/reductase SDR family member 13 isoform X1 [Felis catus] -----------------------MEALLLGAGLLLGAYVLVYYNLV----KAPPCGGIAS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNAAPAPGIS-SCGR----------------- -----THEPFNLLLRVNHIGPFLLTHLLLPRLKTCAPSRVVVVSSAAHRR-GHLDFTRLD RPV-----VGWQQELRAYADSKLANVLFARELATQLEGTG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLSPLLRPLAWLVLRTPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASKRLAGLGPGQDAG-PDEDPQPED PGTPSSRSSPLSEEPTVSEPHPIPHNS-PDLSKVTH-RIQVKTEPEP--- >XP_014954034.2 dehydrogenase/reductase SDR family member 13 [Ovis aries] -----------------------MEALLLGVGLLLGAYVLVYYNLV----KAPPCRGLAS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRR-GRLDFTRLD RPV-----VGWRQELRAYADSKLANVLFARELATQLEGTG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASRKLAGLGPGEDAE-SDEDSQPED PGTPSSPSSPHPEEPTASELYPSPQSS-TDWSTVTR-RIPVKAELEPQAC >XP_018883279.1 dehydrogenase/reductase SDR family member 13 [Gorilla gorilla gorilla] -----------------------MEALLLGAGLLLGAYVLVYYNLV----KAPPCGGMGN LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCR-GRLDFKRLD RPV-----VGWRQELRAYADTKLANVLFARELANQLEATG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASKRLAGLGPGEDAE-PDEDPQSED SEAPSSLSTPHPEEPTVSQPYPSPQSS-PDLSKMTH-RIQAKVEPETQLS >XP_017919816.1 PREDICTED: dehydrogenase/reductase SDR family member 13 [Capra hircus] -----------------------MEALLLGVGLLLGAYVLVYYNLV----KAPPCRGLAS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREPFNLLLRVNHIGPFLLTHLLLPRLKRSAPSRVVVVSSAAHRR-GRLDFTRLD RPV-----VGWRQELRAYADSKLANVLFARELATQLEGTG---VTCYAAHPGPVNS---- ---------DLFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASRKLAGLGPGEDAE-SDEDSQPED PGTPSSPSSPHPEEPTASELYPSPQSSTTDWSTVTR-RIPVKAELEPQAC >XP_025070399.1 dehydrogenase/reductase SDR family member 13 [Alligator sinensis] ------------------------------------------------------------ -----------------------------------------------------------M SLDLASLDSVRAFAETFLRSERRLDLLVLNA----GEA-RGSRLGTKGSQNRXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCAPSRVVVVASNAHRS-GRIDFERLG RPV-----EGVLQNFQAYCDSKLANILFARELAGRLEGTG---VTCYALHPGVVNT---- ---------ALF-SFVPA-------WLRLLFMPFSWLFFQDAVSGAQT-----SIHCATQ EGIEAFSGRFFADCRPQEPRPRARDDTVAR-KLWEVSERMVGLAA--------------- -------------------------------------------------- >XP_016787649.1 dehydrogenase/reductase SDR family member 13 [Pan troglodytes] -----------------------MEALLLGAGLLLGAYVLVYYNLV----KAPPCGGMGN LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCR-GRLDFKRLD RPV-----VGWRQELRAYADTKLANVLFARELANQLEATG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASKRLAGLGPGEDAE-PDEDPQSED SEAPSSLSTPHPEEPTVSQPYPSPQSS-PDLSKMTH-RIQAKVEPEIQLS >XP_019477415.2 dehydrogenase/reductase SDR family member 13 [Meleagris gallopavo] -----------------------MGWWLLGVGLLL--CLLLRFTLR----SPAPLLALPA LRGRTAIVTGGSSGIGEAVARELARCGARVVLATRNALRGEEAAWR-IRRDTGNPEVLFM PLDLSSLHSVHAFATAFLQQEPHLHLLINNA----GVS-AGGT----------------- -----TEDGFSLPFQVNYLGHFLLTRLLLQRLQSSAPSRVIIVASSAHCA-GRLRMAELG RPP-----PGPFAAFQDYCDSKLANVLHARQLAARLQGTG---VTSYAVHPGMGSSVPSG LLVACLHEARLH-LEYPLAR-CSFAWCSLCMQHLSVLCIFYTVHLLHSFPLHDASHCAVR -------GAPLCAVHPLHSSPSARHPFACHIPLCDAS--LCTPHPFAQP----------- -----SLCTPHP---------------------FAH-HIPLHSHPFV--- >XP_014466095.2 PREDICTED: dehydrogenase/reductase SDR family member 13 [Alligator mississippiensis] ------------------------------------------------------------ -----------------------------------------------------------M SLDLASLDSVRAFAETFLRCEPRLDLLVLNA----GIA-SGGR----------------- -----RSDGCNLVFQVNHLGHFLLTQLLLERLKHCAPSRVVVVASSAHRS-GRIDFERLG RPV-----EGVLQNFQAYCDSKLANILFARELAGRLEGTG---VTCYALHPGVVNT---- ---------ALF-SFVPA-------WLWPLFVPFSWLFFRDAMSGAQT-----SIHCATQ EGIEALSGRYFADCRPQEPRPRARDDTVAR-KLWEVSERMVGLAA--------------- -------------------------------------------------- >XP_040194468.1 dehydrogenase/reductase SDR family member 13 [Rana temporaria] -----------------------MAPVLLIPAIVVALYILIYYNFI----QGRQCKSEQR LRGRTVIVTGGNVGIGKMTALDMAKRGARVILACRNKETAEAAAHD-IRRLSGNNEVLFM KLDLASIASIRSFCKTFLDSEPRLDILINNA----GLT-AKGK----------------- -----TEDGFNMVFGVNHLGHFLLTHLLLDRLKQCTPSRIVVLASNAHKM-GRINFKNLN PAG-----ETWLEIFRTYSDSKLANVLFARELANRLQGTE---VTCYAVHPGVVHT---- ---------NLG-RNFPS-------WLQVPLFPFLWLFLRTSMDGAQT-----SIYCSVE EDIEQYSGRYFNNCRVEQVPPHARDDAVAK-KLWEVSEDLLGLNK--------------- -------------------------------------------------- >XP_793866.1 retinol dehydrogenase 12 [Strongylocentrotus purpuratus] MISLSTLSLERVPDFGQRGPGD-LEWTTIALMMVVLVVGLYYYVVK----VADRCSCPKR LDGKTVIVTGANTGIGKETARDLARRGARVILACRDAVRGREAEKD-IRMSTGNDDVIFM KLNLASFDSIRHFAQEFNNTEERLDILVNNA----GVI-NDGSLR--------------- -----TEEGHELVFGVNHLGHFLLTNILLDKLQKCAPSRVINVSSDAYMF-GKLDLERLS VND---------GRVKSYARSKLANVLFTRQLADKMAGTG---VVSFSLHPGSVNT---- ---------EIK-RNWAG-------WLRALAPLISFFFLKSVKAGAQT-----SIHCAVS DDILDQSGEFFKGCQVQKLSRTAQDQDLAQ-RLWDVSLEMTGLQSS-------------- -------------------------------------------------- >XP_038061579.1 retinol dehydrogenase 12-like [Patiria miniata] MLELTSVTLGQWKLWDGPQYHG-FCLGVCVSVALVMCVSVYYYFVK----VADRCTCTTR LDGKTVIITGANTGIGKETAVDLAHRGARVILACRSESRGIQAERE-IREQTGNSHVHFM RLDLASQESVKEFAQEFCNREDRLDILINNA----GVI-NDGSAQ--------------- -----TAEGYELSFGVNHLGHFLLTNLLLAKLQSSSPSRVINVSSDAYQL-GRLGFQDGA GLL-----CGKEGRVKLYARSKLANLLFTHELAKTMEGTD---VAIFALHPGSINT---- ---------DIK-RNWAW-------WLRTLSPLISFLFLKTTTEGAQT-----TIHCAVA EDLQKHSGKYFKGCRVQKVAPMARDDKLSR-KLWRVSLQMTGLTNT-------------- -------------------------------------------------- >XP_031553920.1 retinol dehydrogenase 11-like [Actinia tenebrosa] MASI-------------------PVAVAVGVGGALGLYFARQY--F----KGGEFKSTRR LDGKTVIITGANTGIGKETAIDLAKRGARVIIACRSPDRGKQALKE-IQEQSNSQQVYLE KLDLASLKSVREFAEKIKKNEPRLDILINNA----GVM-MCPYMT--------------- -----TEDGFELQIGVNHLGHFLLTNLLLDLLKKSAPSRVINLSSLGHTMTSRFKFQNMN NEK-------TYGKVEAYAQSKLANILFTKELARRLEGTG---VTTYAVHPGTVET---- ---------ELD-RHTFF----SSSILGAPFRPIRWLTCKTPIQGAQT-----SLYCAVS EDLEGVTGRYYADCAETPSSEASKNEEDAK-TLWDVSVELVGL----------------- -------------------------------------------------- >XP_039255571.1 retinol dehydrogenase 13-like [Styela clava] ---------------------------------------MAEASSV----KNGSVLKDIR MDGKTVLITGANTGIGYETAKDLSSRGAKVIMAGRDAGKVEKAMKE-IKSCDLKANLVGV ELDLASMESIRKCADKIMETEAKLDVLINNA----GIM-SCPQWK--------------- -----TKDGFEMQLGVNHIGHFLFTNLLLDLVKKSSPSRIVILSSSGHTR-GRMNWDDIM SEK-------KYNPFVVYCQSKLANILFARELSRKLEGTG---VTCNSVHPGLVKT---- ---------ELG-RHFMNKEGTWNTIKYYLVFPFVKMIFKTPEQGAQT-----SIYCAVA PELNQVSGKYFADCKIEEEAPAAKNDEDAK-RLWELSLEWTGLKSK-------------- -------------------------------------------------- >AAK93548.1 SD07613p [Drosophila melanogaster] MCIFIDCLL--------------SPLIMWPATIGVGIYFLKEY--M----QGGKFTKDTD ETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKD-IIKETNNQNIFSR ELDLSSLDSIRKFVDGFKKEQPKLHVLINNA----GVM-RCPKTL--------------- -----TKDGYELQLGVNHIGHFLLTNLLLDVLKNSAPSRIVVVSSLAHAR-GSINVADLN SEK-------SYDEGLAYSQSKLANVLFTRELAKRLEGSG---VTVNALHPGVVDT---- ---------ELA-RNWAFF---QTNLVKFFLKPMIWPLLKTPKSGAQT-----SIYAALD PELKNISGLYFSDCKPKPVAPGALDDKVAK-FLWAESEKWTGLDKLEANN---------- -------------------------------------------------- >CAE1254144.1 RDH12 [Sepia pharaonis] -----------------------------MIGLILAGFLIVLFIIICWRHSWGVCTSKTD LTGKTVIITGCNTGIGYYVALDLAFRNARIIMACRNAEKANAAKEK-IIAETGNKQIVFQ QVNLSSLQSVRQFAERIIKEESRLDILINNA----GIM-HSNSLL--------------- -----TEDGLTTIYATNHFAPFLLTNLLLDLLQSSAPSRVINVSSHGHKI-GSIRFENMK CPM-------LDDGNRTYANTKLANVLFTRELARRTEGKG---VSTFSVHPGFCDT---- ---------ELF-RFMPS-------LVQALMT--RYPLMKTAKEGAQT-----ILHCALS EGIESTSGEYYSDCKVSSTSAKGRDMAVAK-KLWEV------L----------------- -------------------------------------------------- >XP_395899.2 retinol dehydrogenase 13 [Apis mellifera] MFSRIAKP---------------FYLYSAGISIIGGAYLLKDY--L----GGNLYDNTDK LNDKIVIVTGANTGIGREIARDLAKREAKVIMACRDMDKCEIARRD-IVIESQNKFVYCR ECDLASQASIRDFVKQFKQEHNNLHILINNA----GVM-RCPKKH--------------- -----TKEGIEMQFGVNHLGHFLLTNLLLDVLKSSAPSRIINVSSSAHKR-GKIKLDDLN SEK-------NYEPGEAYAQSKLANILFTKELANKLKGTG---VTVNAVHPGIVRT---- ---------EIM-RHMGIY---QYYFGRLLADLLTWIFIKTPLKGAQP-----ILFVAID PSLNDVTGEYFVNNKIADVSNEAKNDQIAR-WLWIVSEKWTKLNYM-------------- -------------------------------------------------- >NP_506570.1 DeHydrogenases, Short chain [Caenorhabditis elegans] MDGA-----------DAEEHGGFLFFVLASSVVFIVLFFTRRY--F----KGGQFNERVS AKGLVAVVTGSNCGIGFETVRELNLRKADVYMLCRSEEKANEAKRMLVRQGCDATRLHFI ECDLTDFESVRRAAKETLESTDTIDILINNA----GIMFQSKHEQ--------------- -----TKDGHEKTWQSNHLGPFLLTELFLPAVKKSSYARIINVSSRIHLKSEKINLATVD DKK-------SFGMMKSYRQSKLANVMHARALTKELRKDGAEHVTVNSLHPGVVNT---- ---------ELA-RNTIL----NTPGIKQITAVFRWFLMKTSRDGAQT-----SIFLALG KKIGGISGKYFADCKLTQENPLALDDQACQ-DLYNYSLECTGLAK--------------- -------------------------------------------------- >KAB0360396.1 hypothetical protein FD754_004552 [Muntiacus muntjak] -----------------------MEALLLGVGLLLGAYVLVYYNLV----KAPPCHGLAS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRR-GRLDFTRLD RPV-----VGWRQELRAYADSKLANVLFARELATQLEGSG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASRKLAGLGPGEDAE-SDEDSQPED PGTPSAPSSPHPEEPTASELYPSPQNS-TDRSTVMR-RIPVKAELEPQAC >XP_043759159.1 dehydrogenase/reductase SDR family member 13 isoform X2 [Cervus elaphus] -----------------------MEALLLGVGLLLGAYVLVYYNLV----KAPPCRGLAS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRR-GRLDFTRLD RPV-----VGWRQELRAYADSKLANVLFARELATQLEGTG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASRKLAGLGPGEDAE-SDEDSQPED PGTPSSPSSPHPEEPTASELYPSPQNS-TDRSTVTR-RIPVKAELEPQAC >KAB0367217.1 hypothetical protein FD755_020541 [Muntiacus reevesi] -----------------------MEALLLGVGLLLGAYVLVYYNLV----KAPPCHGLAS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRR-GRLDFTRLD RPV-----VGWRQELRAYADSKLANVLFARELATQLEGSG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASRKLAGLGPGEDAE-SDEDSQPED PGTPSSPSSPHPEEPTASELYPSPQNS-TDRSTVTR-RIPVKAELEPQAC >XP_043335380.1 dehydrogenase/reductase SDR family member 13 isoform X2 [Cervus canadensis] -----------------------MEALLLGVGLLLGAYVLVYYNLV----KAPPCRGLAS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRR-GRLNFTRLD RPV-----VGWRQELRAYADSKLANVLFARELATQLEGTG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASRKLAGLGPGEDAE-SDEDSQPED PGTPSSPSSPHPEEPTASELYPSPQNS-TDRSTVTR-RIPVKAELEPQAC >KAF4012156.1 hypothetical protein G4228_003164 [Cervus hanglu yarkandensis] -----------------------MEALLLGVGLLLGAYVLVYYNLV----KAPPCRGLAS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRR-GRLDFTRLD RPV-----VGWRQELRAYADSKLANVLFARELATQLEGTG---VTCYAAHPGPVNS---- ---------ELFLRHVPG-------WLRPLLRPLAWLVLRAPRGGAQT-----PLYCALQ EGIEPLSGRYFANCHVEEVPPAARDDRAAH-RLWEASRKLAGLGPGEDAE-SDEDSQPVD PGTPSSPSSPHPEEPTASELYPSPQNS-TDRSTVTR-RIPVKAELEPQAC >XP_020767410.1 dehydrogenase/reductase SDR family member 13-like [Odocoileus virginianus texanus] -----------------------MEALLLGVGLLLGAYVLVYYNLV----KAPPCRGLAS LRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFD-LRQESGNNEVIFM ALDLASLASVRAFATAFLSSEPRLDILIHNA----GIS-SCGR----------------- -----TREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRR-GRLDFTRLD RPV-----VGWQQELRAYADSKLANVLFARELATQLEGTG---VTCYAAHPGEVRL---- ----------------SG-------CSASFLFPLS-----HPR----------PLPCSPS LSLSHRTS--------EQEGSLVQGEARSL-LILKPGSPCLGFSSHTTSSDADGWVRHGN EEGLGS----HPKEPSA--------------------------------- >NP_001087976.1 dehydrogenase/reductase (SDR family) member 13 L homeolog [Xenopus laevis] -----------------------MVPVILLLGVGVGAYVLIYFNLI----RGRQCRSDAS LKGKTVIVTGANIGIGKMTALDMARRGARVILACRVKETGEAAAYD-IRQLSGNNQVLFM NLNLSSLESVRSFCRAFLSSEPRLDILINNA----GFS-GPGK----------------- -----TAEGYNIVFGINHLGHFLLTSLLLDRLKQSTPSRIVALASYAHEW-GKIDFNKIS VPS-----DHIKDILQSYCDSKLCNVLFARELANRLEGTG---VTCYSVHPGTVHT---- ---------NLV-RSLPN-------WIKACIKPFTWLFLRTPMDGAQT-----SIYCAVQ EGIEMYTGRYFDNCQVRQVKPHARDDAVAK-KLWEVSERMTGLAS--------------- -------------------------------------------------- >XP_030262215.1 dehydrogenase/reductase SDR family member 13-like isoform X2 [Sparus aurata] -----------------------MSVLLSLVAGAVSFYVIVYYGVF----GGSRCSSSVK LKGKTAIVTGSNTGIGKATALDLAKRGARVILACRNKEKAEAAVFD-IRRESGNNQVMFM LLDLGSLKSVRSFAENFLKSEPRLDILINNA----GIM-GPGH----------------- -----TEDGFGMAFGVNHLGHFLLTNLLLERLQQCGPSRVVTVAALLHRF-GNIDFPPLA SRNKLVSGQSTWHNFRAYCNSKLCNVLFARELANRLEGTS---VTSYSLHPGVVYT---- ---------ELC-RSMSL-------WQLLLMIPFAKLFFLGPEGGSQT-----TLYCALQ EGIEPLSGRYFSNCALQQVGAIGRDDALAK-KLWEVSERLTSVSQETES----------- -------------------------------------------------- >XP_004075984.2 dehydrogenase/reductase SDR family member 13 isoform X1 [Oryzias latipes] MRPSAVSQKPKTT--QEEEVALPSNMLLCVVAGAVSFYLLIYYGVF----RVQRCTSSVR LKGKTVIVTGSNTGIGKSTALALARRGARVILACRSKERGTAAAFD-IRKESGNNQVVFM PLDLADFRSVHSFAETFLETEPRLDILINNA----GIM-GPGR----------------- -----TVDGFGMAFGVNHLGHFLLTNLLLERLKQCGPSRVVTVSALLHHL-GRIDFALLG STKDLVSGQSTWQNFQAYCNSKLCNVLFTRELANHLEGTG---VTCFTLHPGVVYT---- ---------ELC-RNMSW-------WQQLLLIPVAKLFFLDTDGGSQT-----TLHCSLQ EGIESFSGRYFSNCRVQNMGVKGRDDSLAQ-KLWEVSERLTGFHTRVSQ----------- ----------HAERA----------------------------------- >XP_015807550.1 PREDICTED: dehydrogenase/reductase SDR family member 13-like [Nothobranchius furzeri] -----------------------MSIILLAVGVFIGAAFIYHHIVV----KGKKCTSKAE LHGKTVIVTGSNTGIGRTTAINLARRGARVILACRCKQRGEAAQED-IRRESGSNQVVFM QLDLGSLESVRSFAETFLKSEPRLDLLINNA----GIC-MQGR----------------- -----TKDGFGLMFGVNHLGHFLLTNLLLERLKESAPSRIVNVSSMAHNF-GKIDFDSLN THKCLGLGTSSVRVFQIYCDSKLCNVLFNHELAKRLQGTR---VTCYALHPGAISS---- ---------ELG-RNTSS-------LLHVLLKPVTVLFFKNTVQGCQT-----TLHCALQ EGIEPLSGRYFSNCTVRELFAKAKDDAAAK-KLWEISERLCGLV---------------- -------------------------------------------------- >XP_002719556.1 PREDICTED: retinol dehydrogenase 12 [Oryctolagus cuniculus] MLVVL------------------GLLTCFLSVLYVTAPSIRKF--F----AGGVCQTNIQ LPGKVVVITGANTGIGKETARELARRGARVYIACRDILKGESAASE-IRADTKNSQVLVR KLDLSDTKSIRAFAEGFLAEEKQLHILINNA----GVM-LCPQSK--------------- -----TADGFETHLGVNHLGHFLLTYLLLERLKESAPARVVNLASVAHYV-GKIRFHDLQ GEK-------YYCSSFAYCQSKLANVLFTRELAKRLQGTG---VTTYAVHPGIVSS---- ---------ELV-RHS---------FLLCLLWRLFSVFVKSAREGAQT-----SLHCALA EGLEPLSGKYFSDCKRTWVSPRARNNKTAQ-RLWNVSCELLGIQWE-------------- --------------------------------------------------
BMGE Cleaned alignment of selected proteins >sp|Q6UX07|DHR13_HUMAN Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens OX=9606 GN=DHRS13 PE=2 SV=1 EALLLGAGLLLGAYVLVYYNLVKAPPCGGMNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPEI >sp|Q6UX07-2|DHR13_HUMAN Isoform 2 of Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens OX=9606 GN=DHRS13 ------------------------------------------------MTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPEI >sp|Q6UX07-3|DHR13_HUMAN Isoform 3 of Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens OX=9606 GN=DHRS13 EALLLGAGLLLGAYVLVYYNLVKAPPCGGMNLRGRTAVVT---------------------------------------------------------------------------------TREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPEI >tr|F1R2W1|F1R2W1_DANRE Dehydrogenase/reductase (SDR family) member 13a, duplicate 3 OS=Danio rerio OX=7955 GN=dhrs13a.3 PE=1 SV=1 SVLLSVLVGVLAAYVLIYYCLFKGARYKGNTLNGKTAIVTGSNTGIGKTTALDLARRGARVILACRNQERAEAAVYDIRKESGNSEVLYMHLDLASLQSVRDFAETFLKTEPRLDLLINNATEDGFGMAFGVNHLGHFLLTLLLLDRLKQSENSRVVNVSALLHRLGSLDFNLLNTQKAIKAYCHSKLCNVLFTRELANRLEGTSVTCYCLHPGVISTEIG-RYMGPLQKLLCLPMSKLFFLDPEAGAQTTLYCALQEGLEPLSGRYFSSCALQEVGALGRDDALARKLWDVSERLCGLS------------------------------------------------------------ >NP_899109.2 dehydrogenase/reductase SDR family member 13 precursor [Mus musculus] EMLLLGAGLLLGAYVLVYYNLVKAPSCGGISLRGRTVVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVQAFATAFLSSEPRLDVLIHNATRETFNLLLRVNHVGPFLLTHLLLPRLRSCAPSRVVIVSSAAHRRGRLDFTRLDCPVELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHLPGWLRPILRPLAWLVLRAPQGGAQTPLYCALQEGIEPLSGRYFANCHVEEVSPAARDDQAAQRLWKATKKLAGLAPGDDDDPDEEPEPEDPRAPSSQSAPSPEKTTVSGPSHSYQGSQDLSKLTQRIQVKDEPTP >XP_038943561.1 dehydrogenase/reductase SDR family member 13 [Rattus norvegicus] ETLLLGAGLLLGAYVLVYYNLVKAPPCGGISLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLTSVQAFATAFLSSEPRLDILIHNATRETFNLLLRVNHVGPFLLTHLLLPRLRSCAPSRVVIVSSAAHRRGRLDFTRLDCPVELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHLPGWLRPILRPLAWLVLRAPQGGAQTPLYCALQEGIEPLSGRYFANCHVEEVSAAARDDQAAHRLWKVTKKLAGLGPEDDPDTDDEQEPRDPRAPSSLSAPSPEKTTISGPSRSYQGSQDLSKVTQRIHVKDEPTP >NP_001069155.1 dehydrogenase/reductase SDR family member 13 precursor [Bos taurus] EALLLGVGLLLGAYVLVYYNLVKAPPCRGLSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRGRLDFTRLDHPVELRAYANSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAESDEDSQPEDPGTPSSPSSPHPEEPTVSELYPSPQSSTDRSTVTCRIPVKAELEP >XP_002827235.1 dehydrogenase/reductase SDR family member 13 [Pongo abelii] EALLLGAGLLLGAYVLVYYNLVKAPPCGGMNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHRRGRLDFKRLDRPVELRAYADTKLANVLFARELANQLEGTGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPFSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPET >XP_020923154.1 dehydrogenase/reductase SDR family member 13 [Sus scrofa] EALLLGVGLLLGAYVLVYYNLVKAPPCRGISLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREPFNLLLRVNHVGPFLLTHLLLPRLKTCAPSRVVVVSSAAHRRGRLDFTRLDRPVELRAYADSKLANVLFTRELATQLEGTGVTCYAAHPGPVNSELFLRHVPRWLRPLLCPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLEPGEDAESDEEPQPVDPGVPSSLSSPHPEEPAASEPYTSPQSSPDLSKVTRRIPVKAEPEP >XP_003639330.1 dehydrogenase/reductase SDR family member 13 [Canis lupus familiaris] EALLLGAGLLLGAYVLIYYNLVKAPPCGGISLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATHKPFNLLLRVNHIGPFLLTHLLLPRLKTCAPSRVVVVSSAAHRRGRLDFTRLDRPVELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHVPGWLCPLLRPLAWLMLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHQLWEASKRLAGLGPGKDAEADEDSQPEDPRTPSSPSSPHPEEPTVSEPCPTSQSSQDLPKVTRRIQVQTEPEP >XP_003642478.4 dehydrogenase/reductase SDR family member 13 isoform X1 [Gallus gallus] GWWLLVVGLLL--CVLLRFALRSSTPPFALALHGRTAVVTGGSSGIGEAVARELARCGARVVLATRDALRGEEAAWRIRRDTGNPEVLFMPLDLSSLHSVHAFATAFLQQEPHLHLLINNATEDGFSLPFQVNHLGHFLLTQLLLQRLQSSAPSRVVIVASSAHCAGRLRMAELGCPPAFQDYCDSKLANVLHARQLAARLQGTGVTAYAVHPGFVNTRLF-RHAPLWLQLLWTPLSRFCFRSAAEGARTVLFCATQDGLEPFSGCYFADCRPLQPWAQGRDDAAARELWDRSERLLGLQP-------------------SLCTPVE--------------------------------- >XP_034798074.1 dehydrogenase/reductase SDR family member 13 [Pan paniscus] EALLLGAGLLLGAYVLVYYNLVKAPPCGGMNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKMLAGLGPGEDAEPNEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPEI >XP_019673010.1 dehydrogenase/reductase SDR family member 13 isoform X1 [Felis catus] EALLLGAGLLLGAYVLVYYNLVKAPPCGGISLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATHEPFNLLLRVNHIGPFLLTHLLLPRLKTCAPSRVVVVSSAAHRRGHLDFTRLDRPVELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHVPGWLSPLLRPLAWLVLRTPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGQDAGPDEDPQPEDPGTPSSRSSPLSEEPTVSEPHPIPHNSPDLSKVTHRIQVKTEPEP >XP_014954034.2 dehydrogenase/reductase SDR family member 13 [Ovis aries] EALLLGVGLLLGAYVLVYYNLVKAPPCRGLSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRGRLDFTRLDRPVELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAESDEDSQPEDPGTPSSPSSPHPEEPTASELYPSPQSSTDWSTVTRRIPVKAELEP >XP_018883279.1 dehydrogenase/reductase SDR family member 13 [Gorilla gorilla gorilla] EALLLGAGLLLGAYVLVYYNLVKAPPCGGMNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPET >XP_017919816.1 PREDICTED: dehydrogenase/reductase SDR family member 13 [Capra hircus] EALLLGVGLLLGAYVLVYYNLVKAPPCRGLSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREPFNLLLRVNHIGPFLLTHLLLPRLKRSAPSRVVVVSSAAHRRGRLDFTRLDRPVELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSDLFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAESDEDSQPEDPGTPSSPSSPHPEEPTASELYPSPQSSTDWSTVTRRIPVKAELEP >XP_025070399.1 dehydrogenase/reductase SDR family member 13 [Alligator sinensis] -----------------------------------------------------------------------------------------MSLDLASLDSVRAFAETFLRSERRLDLLVLNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCAPSRVVVVASNAHRSGRIDFERLGRPVNFQAYCDSKLANILFARELAGRLEGTGVTCYALHPGVVNTALF-SFVPAWLRLLFMPFSWLFFQDAVSGAQTSIHCATQEGIEAFSGRFFADCRPQEPRPRARDDTVARKLWEVSERMVGLAA----------------------------------------------------------- >XP_016787649.1 dehydrogenase/reductase SDR family member 13 [Pan troglodytes] EALLLGAGLLLGAYVLVYYNLVKAPPCGGMNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPEI >XP_019477415.2 dehydrogenase/reductase SDR family member 13 [Meleagris gallopavo] GWWLLGVGLLL--CLLLRFTLRSPAPLLALALRGRTAIVTGGSSGIGEAVARELARCGARVVLATRNALRGEEAAWRIRRDTGNPEVLFMPLDLSSLHSVHAFATAFLQQEPHLHLLINNATEDGFSLPFQVNYLGHFLLTRLLLQRLQSSAPSRVIIVASSAHCAGRLRMAELGRPPAFQDYCDSKLANVLHARQLAARLQGTGVTSYAVHPGMGSSRLH-LEYPLWCSLCMQHLSVLCIFYTVHLLHSASHCAVR-------GAPLCAVHPLHSSPSARHPFACHPLCDAS--LCTPHPFAQP---------------SLCTPHP--------------------FAHHIPLHSHPFV >XP_014466095.2 PREDICTED: dehydrogenase/reductase SDR family member 13 [Alligator mississippiensis] -----------------------------------------------------------------------------------------MSLDLASLDSVRAFAETFLRCEPRLDLLVLNARSDGCNLVFQVNHLGHFLLTQLLLERLKHCAPSRVVVVASSAHRSGRIDFERLGRPVNFQAYCDSKLANILFARELAGRLEGTGVTCYALHPGVVNTALF-SFVPAWLWPLFVPFSWLFFRDAMSGAQTSIHCATQEGIEALSGRYFADCRPQEPRPRARDDTVARKLWEVSERMVGLAA----------------------------------------------------------- >XP_040194468.1 dehydrogenase/reductase SDR family member 13 [Rana temporaria] APVLLIPAIVVALYILIYYNFIQGRQCKSERLRGRTVIVTGGNVGIGKMTALDMAKRGARVILACRNKETAEAAAHDIRRLSGNNEVLFMKLDLASIASIRSFCKTFLDSEPRLDILINNATEDGFNMVFGVNHLGHFLLTHLLLDRLKQCTPSRIVVLASNAHKMGRINFKNLNPAGIFRTYSDSKLANVLFARELANRLQGTEVTCYAVHPGVVHTNLG-RNFPSWLQVPLFPFLWLFLRTSMDGAQTSIYCSVEEDIEQYSGRYFNNCRVEQVPPHARDDAVAKKLWEVSEDLLGLNK----------------------------------------------------------- >XP_793866.1 retinol dehydrogenase 12 [Strongylocentrotus purpuratus] EWTTIALMMVVLVVGLYYYVVKVADRCSCPRLDGKTVIVTGANTGIGKETARDLARRGARVILACRDAVRGREAEKDIRMSTGNDDVIFMKLNLASFDSIRHFAQEFNNTEERLDILVNNATEEGHELVFGVNHLGHFLLTNILLDKLQKCAPSRVINVSSDAYMFGKLDLERLSVNDRVKSYARSKLANVLFTRQLADKMAGTGVVSFSLHPGSVNTEIK-RNWAGWLRALAPLISFFFLKSVKAGAQTSIHCAVSDDILDQSGEFFKGCQVQKLSRTAQDQDLAQRLWDVSLEMTGLQSS---------------------------------------------------------- >XP_038061579.1 retinol dehydrogenase 12-like [Patiria miniata] CLGVCVSVALVMCVSVYYYFVKVADRCTCTRLDGKTVIITGANTGIGKETAVDLAHRGARVILACRSESRGIQAEREIREQTGNSHVHFMRLDLASQESVKEFAQEFCNREDRLDILINNATAEGYELSFGVNHLGHFLLTNLLLAKLQSSSPSRVINVSSDAYQLGRLGFQDGAGLLRVKLYARSKLANLLFTHELAKTMEGTDVAIFALHPGSINTDIK-RNWAWWLRTLSPLISFLFLKTTTEGAQTTIHCAVAEDLQKHSGKYFKGCRVQKVAPMARDDKLSRKLWRVSLQMTGLTNT---------------------------------------------------------- >XP_031553920.1 retinol dehydrogenase 11-like [Actinia tenebrosa] VAVAVGVGGALGLYFARQY--FKGGEFKSTRLDGKTVIITGANTGIGKETAIDLAKRGARVIIACRSPDRGKQALKEIQEQSNSQQVYLEKLDLASLKSVREFAEKIKKNEPRLDILINNATEDGFELQIGVNHLGHFLLTNLLLDLLKKSAPSRVINLSSLGHTMSRFKFQNMNNEKKVEAYAQSKLANILFTKELARRLEGTGVTTYAVHPGTVETELD-RHTFFILGAPFRPIRWLTCKTPIQGAQTSLYCAVSEDLEGVTGRYYADCAETPSSEASKNEEDAKTLWDVSVELVGL------------------------------------------------------------- >XP_039255571.1 retinol dehydrogenase 13-like [Styela clava] ---------------MAEASSVKNGSVLKDRMDGKTVLITGANTGIGYETAKDLSSRGAKVIMAGRDAGKVEKAMKEIKSCDLKANLVGVELDLASMESIRKCADKIMETEAKLDVLINNATKDGFEMQLGVNHIGHFLFTNLLLDLVKKSSPSRIVILSSSGHTRGRMNWDDIMSEKPFVVYCQSKLANILFARELSRKLEGTGVTCNSVHPGLVKTELG-RHFMNIKYYLVFPFVKMIFKTPEQGAQTSIYCAVAPELNQVSGKYFADCKIEEEAPAAKNDEDAKRLWELSLEWTGLKSK---------------------------------------------------------- >AAK93548.1 SD07613p [Drosophila melanogaster] PLIMWPATIGVGIYFLKEY--MQGGKFTKDDETGKVFIVTGANTGIGKETALEIARRGGTVYLACRDMNRCEKARKDIIKETNNQNIFSRELDLSSLDSIRKFVDGFKKEQPKLHVLINNATKDGYELQLGVNHIGHFLLTNLLLDVLKNSAPSRIVVVSSLAHARGSINVADLNSEKEGLAYSQSKLANVLFTRELAKRLEGSGVTVNALHPGVVDTELA-RNWAFLVKFFLKPMIWPLLKTPKSGAQTSIYAALDPELKNISGLYFSDCKPKPVAPGALDDKVAKFLWAESEKWTGLDKLEANN------------------------------------------------------ >CAE1254144.1 RDH12 [Sepia pharaonis] -----MIGLILAGFLIVLFIIISWGVCTSKDLTGKTVIITGCNTGIGYYVALDLAFRNARIIMACRNAEKANAAKEKIIAETGNKQIVFQQVNLSSLQSVRQFAERIIKEESRLDILINNATEDGLTTIYATNHFAPFLLTNLLLDLLQSSAPSRVINVSSHGHKIGSIRFENMKCPMGNRTYANTKLANVLFTRELARRTEGKGVSTFSVHPGFCDTELF-RFMPSLVQALMT--RYPLMKTAKEGAQTILHCALSEGIESTSGEYYSDCKVSSTSAKGRDMAVAKKLWEV------L------------------------------------------------------------- >XP_395899.2 retinol dehydrogenase 13 [Apis mellifera] YLYSAGISIIGGAYLLKDY--LGGNLYDNTKLNDKIVIVTGANTGIGREIARDLAKREAKVIMACRDMDKCEIARRDIVIESQNKFVYCRECDLASQASIRDFVKQFKQEHNNLHILINNATKEGIEMQFGVNHLGHFLLTNLLLDVLKSSAPSRIINVSSSAHKRGKIKLDDLNSEKPGEAYAQSKLANILFTKELANKLKGTGVTVNAVHPGIVRTEIM-RHMGIFGRLLADLLTWIFIKTPLKGAQPILFVAIDPSLNDVTGEYFVNNKIADVSNEAKNDQIARWLWIVSEKWTKLNYM---------------------------------------------------------- >NP_506570.1 DeHydrogenases, Short chain [Caenorhabditis elegans] FFVLASSVVFIVLFFTRRY--FKGGQFNERSAKGLVAVVTGSNCGIGFETVRELNLRKADVYMLCRSEEKANEAKRMVRQGCDATRLHFIECDLTDFESVRRAAKETLESTDTIDILINNATKDGHEKTWQSNHLGPFLLTELFLPAVKKSSYARIINVSSRIHLKEKINLATVDDKKMMKSYRQSKLANVMHARALTKELRKDGVTVNSLHPGVVNTELA-RNTILGIKQITAVFRWFLMKTSRDGAQTSIFLALGKKIGGISGKYFADCKLTQENPLALDDQACQDLYNYSLECTGLAK----------------------------------------------------------- >KAB0360396.1 hypothetical protein FD754_004552 [Muntiacus muntjak] EALLLGVGLLLGAYVLVYYNLVKAPPCHGLSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRGRLDFTRLDRPVELRAYADSKLANVLFARELATQLEGSGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAESDEDSQPEDPGTPSAPSSPHPEEPTASELYPSPQNSTDRSTVMRRIPVKAELEP >XP_043759159.1 dehydrogenase/reductase SDR family member 13 isoform X2 [Cervus elaphus] EALLLGVGLLLGAYVLVYYNLVKAPPCRGLSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRGRLDFTRLDRPVELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAESDEDSQPEDPGTPSSPSSPHPEEPTASELYPSPQNSTDRSTVTRRIPVKAELEP >KAB0367217.1 hypothetical protein FD755_020541 [Muntiacus reevesi] EALLLGVGLLLGAYVLVYYNLVKAPPCHGLSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRGRLDFTRLDRPVELRAYADSKLANVLFARELATQLEGSGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAESDEDSQPEDPGTPSSPSSPHPEEPTASELYPSPQNSTDRSTVTRRIPVKAELEP >XP_043335380.1 dehydrogenase/reductase SDR family member 13 isoform X2 [Cervus canadensis] EALLLGVGLLLGAYVLVYYNLVKAPPCRGLSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRGRLNFTRLDRPVELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAESDEDSQPEDPGTPSSPSSPHPEEPTASELYPSPQNSTDRSTVTRRIPVKAELEP >KAF4012156.1 hypothetical protein G4228_003164 [Cervus hanglu yarkandensis] EALLLGVGLLLGAYVLVYYNLVKAPPCRGLSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRGRLDFTRLDRPVELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAESDEDSQPVDPGTPSSPSSPHPEEPTASELYPSPQNSTDRSTVTRRIPVKAELEP >XP_020767410.1 dehydrogenase/reductase SDR family member 13-like [Odocoileus virginianus texanus] EALLLGVGLLLGAYVLVYYNLVKAPPCRGLSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNATREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRGRLDFTRLDRPVELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGEVRL-------SGCSASFLFPLS-----HPR-----PLPCSPSLSLSHRTS--------EQEGSLVQGEARSLLILKPGSPCLGFSSHTTSSADGWVRHGNEEGLGS----HPKEPSA---------------------------- >NP_001087976.1 dehydrogenase/reductase (SDR family) member 13 L homeolog [Xenopus laevis] VPVILLLGVGVGAYVLIYFNLIRGRQCRSDSLKGKTVIVTGANIGIGKMTALDMARRGARVILACRVKETGEAAAYDIRQLSGNNQVLFMNLNLSSLESVRSFCRAFLSSEPRLDILINNATAEGYNIVFGINHLGHFLLTSLLLDRLKQSTPSRIVALASYAHEWGKIDFNKISVPSILQSYCDSKLCNVLFARELANRLEGTGVTCYSVHPGTVHTNLV-RSLPNWIKACIKPFTWLFLRTPMDGAQTSIYCAVQEGIEMYTGRYFDNCQVRQVKPHARDDAVAKKLWEVSERMTGLAS----------------------------------------------------------- >XP_030262215.1 dehydrogenase/reductase SDR family member 13-like isoform X2 [Sparus aurata] SVLLSLVAGAVSFYVIVYYGVFGGSRCSSSKLKGKTAIVTGSNTGIGKATALDLAKRGARVILACRNKEKAEAAVFDIRRESGNNQVMFMLLDLGSLKSVRSFAENFLKSEPRLDILINNATEDGFGMAFGVNHLGHFLLTNLLLERLQQCGPSRVVTVAALLHRFGNIDFPPLASRNNFRAYCNSKLCNVLFARELANRLEGTSVTSYSLHPGVVYTELC-RSMSLWQLLLMIPFAKLFFLGPEGGSQTTLYCALQEGIEPLSGRYFSNCALQQVGAIGRDDALAKKLWEVSERLTSVSQETES------------------------------------------------------- >XP_004075984.2 dehydrogenase/reductase SDR family member 13 isoform X1 [Oryzias latipes] NMLLCVVAGAVSFYLLIYYGVFRVQRCTSSRLKGKTVIVTGSNTGIGKSTALALARRGARVILACRSKERGTAAAFDIRKESGNNQVVFMPLDLADFRSVHSFAETFLETEPRLDILINNATVDGFGMAFGVNHLGHFLLTNLLLERLKQCGPSRVVTVSALLHHLGRIDFALLGSTKNFQAYCNSKLCNVLFTRELANHLEGTGVTCFTLHPGVVYTELC-RNMSWWQQLLLIPVAKLFFLDTDGGSQTTLHCSLQEGIESFSGRYFSNCRVQNMGVKGRDDSLAQKLWEVSERLTGFHTRVSQ--------------------HAERA------------------------------ >XP_015807550.1 PREDICTED: dehydrogenase/reductase SDR family member 13-like [Nothobranchius furzeri] SIILLAVGVFIGAAFIYHHIVVKGKKCTSKELHGKTVIVTGSNTGIGRTTAINLARRGARVILACRCKQRGEAAQEDIRRESGSNQVVFMQLDLGSLESVRSFAETFLKSEPRLDLLINNATKDGFGLMFGVNHLGHFLLTNLLLERLKESAPSRIVNVSSMAHNFGKIDFDSLNTHKVFQIYCDSKLCNVLFNHELAKRLQGTRVTCYALHPGAISSELG-RNTSSLLHVLLKPVTVLFFKNTVQGCQTTLHCALQEGIEPLSGRYFSNCTVRELFAKAKDDAAAKKLWEISERLCGLV------------------------------------------------------------ >XP_002719556.1 PREDICTED: retinol dehydrogenase 12 [Oryctolagus cuniculus] LLTCFLSVLYVTAPSIRKF--FAGGVCQTNQLPGKVVVITGANTGIGKETARELARRGARVYIACRDILKGESAASEIRADTKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNATADGFETHLGVNHLGHFLLTYLLLERLKESAPARVVNLASVAHYVGKIRFHDLQGEKSSFAYCQSKLANVLFTRELAKRLQGTGVTTYAVHPGIVSSELV-RHS--FLLCLLWRLFSVFVKSAREGAQTSLHCALAEGLEPLSGKYFSDCKRTWVSPRARNNKTAQRLWNVSCELLGIQWE----------------------------------------------------------
PhyML tree of selected proteins (((((((XP_003642478_4_dehydrogenase_reductase_SDR_family_member_13_isoform_X1__Gallus_gallus_:0.07156201,XP_019477415_2_dehydrogenase_reductase_SDR_family_member_13__Meleagris_gallopavo_:0.38784113):0.66668405,(XP_014466095_2_PREDICTED__dehydrogenase_reductase_SDR_family_member_13__Alligator_mississippiensis_:0.03070253,XP_025070399_1_dehydrogenase_reductase_SDR_family_member_13__Alligator_sinensis_:0.04111534):0.17174637):0.15460261,((XP_019673010_1_dehydrogenase_reductase_SDR_family_member_13_isoform_X1__Felis_catus_:0.04439616,((XP_003639330_1_dehydrogenase_reductase_SDR_family_member_13__Canis_lupus_familiaris_:0.04593507,(NP_899109_2_dehydrogenase_reductase_SDR_family_member_13_precursor__Mus_musculus_:0.02843324,XP_038943561_1_dehydrogenase_reductase_SDR_family_member_13__Rattus_norvegicus_:0.03807408):0.12219846):0.01036473,(XP_020923154_1_dehydrogenase_reductase_SDR_family_member_13__Sus_scrofa_:0.03376856,((NP_001069155_1_dehydrogenase_reductase_SDR_family_member_13_precursor__Bos_taurus_:0.01275241,(XP_043759159_1_dehydrogenase_reductase_SDR_family_member_13_isoform_X2__Cervus_elaphus_:0.00000001,(KAF4012156_1_hypothetical_protein_G4228_003164__Cervus_hanglu_yarkandensis_:0.00318193,(XP_043335380_1_dehydrogenase_reductase_SDR_family_member_13_isoform_X2__Cervus_canadensis_:0.00316727,(KAB0367217_1_hypothetical_protein_FD755_020541__Muntiacus_reevesi_:0.00000001,KAB0360396_1_hypothetical_protein_FD754_004552__Muntiacus_muntjak_:0.00633964):0.00634953):0.00000001):0.00000001):0.00315347):0.00319127,(XP_017919816_1_PREDICTED__dehydrogenase_reductase_SDR_family_member_13__Capra_hircus_:0.00638586,(XP_020767410_1_dehydrogenase_reductase_SDR_family_member_13_like__Odocoileus_virginianus_texanus_:0.40300529,XP_014954034_2_dehydrogenase_reductase_SDR_family_member_13__Ovis_aries_:0.00000001):0.00000001):0.00000001):0.03617888):0.02000756):0.0029898):0.03996727,(XP_002827235_1_dehydrogenase_reductase_SDR_family_member_13__Pongo_abelii_:0.00315882,(XP_018883279_1_dehydrogenase_reductase_SDR_family_member_13__Gorilla_gorilla_gorilla_:0.00000001,((sp_Q6UX07_DHR13_HUMAN_Dehydrogenase_reductase_SDR_family_member_13_OS_Homo_sapiens_OX_9606_GN_DHRS13_PE_2_SV_1:0.00000001,XP_016787649_1_dehydrogenase_reductase_SDR_family_member_13__Pan_troglodytes_:0.00000001):0.00000001,(XP_034798074_1_dehydrogenase_reductase_SDR_family_member_13__Pan_paniscus_:0.00628816,(sp_Q6UX07_3_DHR13_HUMAN_Isoform_3_of_Dehydrogenase_reductase_SDR_family_member_13_OS_Homo_sapiens_OX_9606_GN_DHRS13:0.00000001,sp_Q6UX07_2_DHR13_HUMAN_Isoform_2_of_Dehydrogenase_reductase_SDR_family_member_13_OS_Homo_sapiens_OX_9606_GN_DHRS13:0.00000001):0.00000001):0.00000001):0.00315633):0.00950648):0.02541347):0.39973134):0.1833521,(XP_040194468_1_dehydrogenase_reductase_SDR_family_member_13__Rana_temporaria_:0.2423751,NP_001087976_1_dehydrogenase_reductase__SDR_family__member_13_L_homeolog__Xenopus_laevis_:0.28418545):0.19136209):0.11940586,(XP_015807550_1_PREDICTED__dehydrogenase_reductase_SDR_family_member_13_like__Nothobranchius_furzeri_:0.41474916,(tr_F1R2W1_F1R2W1_DANRE_Dehydrogenase_reductase__SDR_family__member_13a__duplicate_3_OS_Danio_rerio_OX_7955_GN_dhrs13a_3_PE_1_SV_1:0.28109208,(XP_030262215_1_dehydrogenase_reductase_SDR_family_member_13_like_isoform_X2__Sparus_aurata_:0.1805194,XP_004075984_2_dehydrogenase_reductase_SDR_family_member_13_isoform_X1__Oryzias_latipes_:0.24252084):0.09999755):0.18264899):0.08284283):0.1807044,(CAE1254144_1_RDH12__Sepia_pharaonis_:0.94615677,(XP_002719556_1_PREDICTED__retinol_dehydrogenase_12__Oryctolagus_cuniculus_:0.80474631,(XP_031553920_1_retinol_dehydrogenase_11_like__Actinia_tenebrosa_:0.60644388,((XP_039255571_1_retinol_dehydrogenase_13_like__Styela_clava_:0.55682211,NP_506570_1_DeHydrogenases__Short_chain__Caenorhabditis_elegans_:1.56430431):0.23700018,(XP_395899_2_retinol_dehydrogenase_13__Apis_mellifera_:0.71062712,AAK93548_1_SD07613p__Drosophila_melanogaster_:0.50083592):0.18311151):0.21135426):0.1043403):0.12841002):0.09538327):0.62738036,XP_793866_1_retinol_dehydrogenase_12__Strongylocentrotus_purpuratus_:0.390268,XP_038061579_1_retinol_dehydrogenase_12_like__Patiria_miniata_:0.38375144);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)