PB0147

DATABASE

Click here to access PB0147 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0147	P08572	Collagen alpha-2(IV) chain	COL4A2	BSVD2, ICH, POREN2, collagen type IV alpha 2 chain	Homo_sapiens	Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.

Domains

Gene Ontology

PF01391 (17_Collagen) PF01413 (2_C4)

GO:0005201 (enables) extracellular matrix structural constituent GO:0005515 (enables) protein binding GO:0030020 (enables) extracellular matrix structural constituent conferring tensile strength GO:0001525 (involved in) angiogenesis GO:0006351 (involved in) transcription, DNA-templated GO:0007568 (involved in) aging GO:0014823 (involved in) response to activity GO:0016525 (involved in) negative regulation of angiogenesis GO:0030198 (involved in) extracellular matrix organization GO:0035987 (involved in) endodermal cell differentiation GO:0038063 (involved in) collagen-activated tyrosine kinase receptor signaling pathway GO:0071560 (involved in) cellular response to transforming growth factor beta stimulus GO:0005615 (is active in) extracellular space GO:0031012 (is active in) extracellular matrix GO:0005576 (located in) extracellular region GO:0005604 (located in) basement membrane GO:0005788 (located in) endoplasmic reticulum lumen GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome GO:0005581 (part of) collagen trimer GO:0005587 (part of) collagen type IV trimer

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P08572|CO4A2_HUMAN Collagen alpha-2(IV) chain OS=Homo sapiens OX=9606 GN=COL4A2 PE=1 SV=4 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGR GQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIP GHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERD RYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKG EKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGF PGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKG ARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPAL YGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDA GECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGA PGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPP GDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQID CDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRG LPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQ PGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGL HGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGH PGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGL AGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLS GIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGL YGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTG VQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHG LPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPG SPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPG TPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPG APGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQ GRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQ EPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASR NDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLW IGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIP EQSFQGSPSADTLKAGLIRTHISRCQVCMKNL >tr|A0A0H2UKP2|A0A0H2UKP2_DANRE Collagen, type IV, alpha 2 OS=Danio rerio OX=7955 GN=col4a2 PE=1 SV=2 EGENIIIHINTFRSFTLIITVVILTSTTFSGVKKSTGPCGGRDCSGGCQCYPEKGARGLP GPLGPQGPTGPKGRQGEPGLQGPKGMKGEHGEAGFVGPKGSVGMEGVPGFNGADGVPGHP GPSGARGKAGPDGCNGTRGDSGMPGFPGLEGGQGTPGWPGMKGEKGDPLEVWVYMERFRG DPGPAGFPGIVGPTGDPGYRGLPGFQGPWGPQGLKGAKGQKGERTKILKGVKGELGEIGE PGPPGVFSQTSPIPSDWQGEKGKMGSKGDKGDLGYLSTKAESGVSGFAGARGNPGLDGWP GPRGDTGLPGFPGNNGRKGDVGEPGELVGSPFDDTGVGPPGPPGERGPVGNYGRKGAKGQ PGPPGPPPYGQQTVELWGPEGPRGPKGASGETGEPGNPATQPGPPGPDGSPGSVGPPGPK GSLEEYFKGSPGHRGRPGSAGKKGPKGDHGLCECSVKPPPGPPGPPGDSGDPGMAGEWGQ QGDQGDPGTKGANGLPGFPGTEGLPGPKGRKGELMEAVQKGSAGDPGDPGHSGFPGEQGR PGIDGRDGEPGFRGPPGEGPVGEPGAKGYSGPPGRSGLIGPKGNPGQVLGATKGLSGLPG DDGQTGPDGRTGPPGPPGDCSSRGGSQWSIPVECIGDPGPPGESGLPGPRGLEGFPGVPG PKGTAGFSGDLGDKGERGEPGRGGPPGPKGFTGPRGDLGYPGTKGVKGPPGLSGKPGLDG ASGGKGEHGEVFGASSGAPGDPGLPGHRGDTGLTGDPGLPGYFGMEGMPGMTGLKGESGP PGLQGEQGRPGPPGTFGFPGQTGYTGPPGPPGNIGEPGPSGRRGDQGEPGLIGARGVKGA IGDPGNIGVTGNIGPPGDQGETGGPGFFGLPGLKGSKGGQGMTGFPGKTGERGLKGFSGT KGEIGLPGHQGAKGAPGSPGQKGDRGLTGPPGDKPVIHITPHMKEVMKGSKGDHGNMGDP GFTGPRGTKGFPGIPGGEGKDGHPGEPSVVKGVKGLPGEPGLEGPKGMPGPTGLPGIEGF PGMSGPKGNKGSSGAYGRPGDSGIKGFKGDLGPTISLPGSTGLRGETGHPGSTGAKGLYG MPGERGSSGLDGIEGMKGYQGEPGTVGPPGSDGLQGFPGSQGHKGRSGDPGQTGTTGIQG QPGQKGFPGLKGIFGLDGLKGQKGNQGVPGTDNWGQPGNPGTKGELGETGIPSTTTGVPG SLGHKGTTGDSGNKGEIGQRGVPGPQGQQGFSDIKGTQGDYGFPGIKGIPGFPGTRGTPG IPSPFGAKGDRGNVGDFGLFGEKGVQGDRGEKGSSGESGVSGRKGDKGEPGMMGFPGRRG FQGDRGPFGPKGDTGPPGFPGLPGAKGYPPVPQKLPGEQGPPGQMGIQGPSGRNGNPGPA GPPGDSGFVGPSGHKGMPGLPGIPGSPGFRGEPGSMGHSGLQGEQGTRGRPGMPGPLGMA GRSVNVGYLLVKHSQSEEIPMCPQGMSLLWMGYSLLYFEGQEKAHNQDLGLAGSCLPRFN TMPFLYCNPGDICYYASRNDKSYWLSTTQPIPMMPVEESEIKPYISRCSVCEAPSVAIAV HSQDTTIPNCPVGWRSLWIGYSFLMHTAAGDEGGGQSLASPGSCLEDFRTTPFIECNGAK GTCHYFANKHSFWLTSIDESFQSSPSSETLKAGQLLSRISRCQVCMKNL
Selected proteins from model organisms >sp|P08572|CO4A2_HUMAN Collagen alpha-2(IV) chain OS=Homo sapiens OX=9606 GN=COL4A2 PE=1 SV=4 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGR GQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIP GHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERD RYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKG EKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGF PGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKG ARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPAL YGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDA GECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGA PGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPP GDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQID CDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRG LPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQ PGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGL HGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGH PGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGL AGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLS GIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGL YGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTG VQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHG LPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPG SPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPG TPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPG APGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQ GRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQ EPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASR NDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLW IGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIP EQSFQGSPSADTLKAGLIRTHISRCQVCMKNL >tr|A0A0H2UKP2|A0A0H2UKP2_DANRE Collagen, type IV, alpha 2 OS=Danio rerio OX=7955 GN=col4a2 PE=1 SV=2 EGENIIIHINTFRSFTLIITVVILTSTTFSGVKKSTGPCGGRDCSGGCQCYPEKGARGLP GPLGPQGPTGPKGRQGEPGLQGPKGMKGEHGEAGFVGPKGSVGMEGVPGFNGADGVPGHP GPSGARGKAGPDGCNGTRGDSGMPGFPGLEGGQGTPGWPGMKGEKGDPLEVWVYMERFRG DPGPAGFPGIVGPTGDPGYRGLPGFQGPWGPQGLKGAKGQKGERTKILKGVKGELGEIGE PGPPGVFSQTSPIPSDWQGEKGKMGSKGDKGDLGYLSTKAESGVSGFAGARGNPGLDGWP GPRGDTGLPGFPGNNGRKGDVGEPGELVGSPFDDTGVGPPGPPGERGPVGNYGRKGAKGQ PGPPGPPPYGQQTVELWGPEGPRGPKGASGETGEPGNPATQPGPPGPDGSPGSVGPPGPK GSLEEYFKGSPGHRGRPGSAGKKGPKGDHGLCECSVKPPPGPPGPPGDSGDPGMAGEWGQ QGDQGDPGTKGANGLPGFPGTEGLPGPKGRKGELMEAVQKGSAGDPGDPGHSGFPGEQGR PGIDGRDGEPGFRGPPGEGPVGEPGAKGYSGPPGRSGLIGPKGNPGQVLGATKGLSGLPG DDGQTGPDGRTGPPGPPGDCSSRGGSQWSIPVECIGDPGPPGESGLPGPRGLEGFPGVPG PKGTAGFSGDLGDKGERGEPGRGGPPGPKGFTGPRGDLGYPGTKGVKGPPGLSGKPGLDG ASGGKGEHGEVFGASSGAPGDPGLPGHRGDTGLTGDPGLPGYFGMEGMPGMTGLKGESGP PGLQGEQGRPGPPGTFGFPGQTGYTGPPGPPGNIGEPGPSGRRGDQGEPGLIGARGVKGA IGDPGNIGVTGNIGPPGDQGETGGPGFFGLPGLKGSKGGQGMTGFPGKTGERGLKGFSGT KGEIGLPGHQGAKGAPGSPGQKGDRGLTGPPGDKPVIHITPHMKEVMKGSKGDHGNMGDP GFTGPRGTKGFPGIPGGEGKDGHPGEPSVVKGVKGLPGEPGLEGPKGMPGPTGLPGIEGF PGMSGPKGNKGSSGAYGRPGDSGIKGFKGDLGPTISLPGSTGLRGETGHPGSTGAKGLYG MPGERGSSGLDGIEGMKGYQGEPGTVGPPGSDGLQGFPGSQGHKGRSGDPGQTGTTGIQG QPGQKGFPGLKGIFGLDGLKGQKGNQGVPGTDNWGQPGNPGTKGELGETGIPSTTTGVPG SLGHKGTTGDSGNKGEIGQRGVPGPQGQQGFSDIKGTQGDYGFPGIKGIPGFPGTRGTPG IPSPFGAKGDRGNVGDFGLFGEKGVQGDRGEKGSSGESGVSGRKGDKGEPGMMGFPGRRG FQGDRGPFGPKGDTGPPGFPGLPGAKGYPPVPQKLPGEQGPPGQMGIQGPSGRNGNPGPA GPPGDSGFVGPSGHKGMPGLPGIPGSPGFRGEPGSMGHSGLQGEQGTRGRPGMPGPLGMA GRSVNVGYLLVKHSQSEEIPMCPQGMSLLWMGYSLLYFEGQEKAHNQDLGLAGSCLPRFN TMPFLYCNPGDICYYASRNDKSYWLSTTQPIPMMPVEESEIKPYISRCSVCEAPSVAIAV HSQDTTIPNCPVGWRSLWIGYSFLMHTAAGDEGGGQSLASPGSCLEDFRTTPFIECNGAK GTCHYFANKHSFWLTSIDESFQSSPSSETLKAGQLLSRISRCQVCMKNL >NP_034062.3 collagen alpha-2(IV) chain precursor [Mus musculus] MDRVRFKASGPPLRGWLLLATVTVGLLAQSVLGGVKKLDVPCGGRDCSGGCQCYPEKGARGQPGAVGPQG YNGPPGLQGFPGLQGRKGDKGERGVPGPTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGT RGDAGPQGPSGSGGFPGLPGPQGPKGQKGEPYALSKEDRDKYRGEPGEPGLVGYQGPPGRPGPIGQMGPM GAPGRPGPPGPPGPKGQPGNRGLGFYGQKGEKGDIGQPGPNGIPSDITLVGPTTSTIHPDLYKGEKGDEG EQGIPGVISKGEEGIMGFPGIRGFPGLDGEKGVVGQKGSRGLDGFQGPSGPRGPKGERGEQGPPGPSVYS PHPSLAKGARGDPGFQGAHGEPGSRGEPGEPGTAGPPGPSVGDEDSMRGLPGEMGPKGFSGEPGSPARYL GPPGADGRPGPQGVPGPAGPPGPDGFLFGLKGSEGRVGYPGPSGFPGTRGQKGWKGEAGDCQCGQVIGGL PGLPGPKGFPGVNGELGKKGDQGDPGLHGIPGFPGFKGAPGVAGAPGPKGIKGDSRTITTKGERGQPGIP GVHGMKGDDGVPGRDGLDGFPGLPGPPGDGIKGPPGDAGLPGVPGTKGFPGDIGPPGQGLPGPKGERGFP GDAGLPGPPGFPGPPGPPGTPGQRDCDTGVKRPIGGGQQVVVQPGCIEGPTGSPGQPGPPGPTGAKGVRG MPGFPGASGEQGLKGFPGDPGREGFPGPPGFMGPRGSKGTTGLPGPDGPPGPIGLPGPAGPPGDRGIPGE VLGAQPGTRGDAGLPGQPGLKGLPGETGAPGFRGSQGMPGMPGLKGQPGFPGPSGQPGQSGPPGQHGFPG TPGREGPLGQPGSPGLGGLPGDRGEPGDPGVPGPVGMKGLSGDRGDAGMSGERGHPGSPGFKGMAGMPGI PGQKGDRGSPGMDGFQGMLGLKGRQGFPGTKGEAGFFGVPGLKGLPGEPGVKGNRGDRGPPGPPPLILPG MKDIKGEKGDEGPMGLKGYLGLKGIQGMPGVPGVSGFPGLPGRPGFIKGVKGDIGVPGTPGLPGFPGVSG PPGITGFPGFTGSRGEKGTPGVAGVFGETGPTGDFGDIGDTVDLPGSPGLKGERGITGIPGLKGFFGEKG AAGDIGFPGITGMAGAQGSPGLKGQTGFPGLTGLQGPQGEPGRIGIPGDKGDFGWPGVPGLPGFPGIRGI SGLHGLPGTKGFPGSPGVDAHGDPGFPGPTGDRGDRGEANTLPGPVGVPGQKGERGTPGERGPAGSPGLQ GFPGISPPSNISGSPGDVGAPGIFGLQGYQGPPGPPGPNALPGIKGDEGSSGAAGFPGQKGWVGDPGPQG QPGVLGLPGEKGPKGEQGFMGNTGPSGAVGDRGPKGPKGDQGFPGAPGSMGSPGIPGIPQKIAVQPGTLG PQGRRGLPGALGEIGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPVGQEGEPGRPGS PGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMP FLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEEEIKPYISRCSVCEAPAVAIAVHSQDTSIPHCPAG WRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYFANKYSFWLTTIPEQNFQ STPSADTLKAGLIRTHISRCQVCMKNL >XP_038951185.1 collagen alpha-2(IV) chain [Rattus norvegicus] MDRVRFSASGLPLRGWLLLATVTVGLLAQSVLGGVKKSDVPCGGRDCSGGCQCFPEKGARGQPGEVGPQG YNGPPGLQGFPGLQGRKGDKGERGAPGPTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGT RGDAGPQGPSGTGGFPGLPGPQGPKGQKGEPYALSKEDRDKYRGEPGEPGSVGYQGPPGRPGPIGQMGPM GAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDVGQPGPNGIPSDITLIGPTPSTYHPDMYKGEKGSQG EPGIPGITLKGEEGIMGFPGTRGFPGLDGEKGVSGQKGSRGLDGFQGPSGPRGPKGERGELGPPGPPAYS PHPSLAKGARGDPGFQGAHGEPGSRGEPGDPGPVGPPGLSIGDEDSKRGLPGEMGPKGFSGEPGPSAYYP GPPGADGKPGPQGLPGPAGPPGPDGFLFGLKGSEGRVGYPGPSGFPGGRGQKGWKGEAGDCQCGQVIPGL PGLPGPKGFPGVNGEFGKKGDQGDPGLHGIPGFPGFKGAPGIAGAPGPKGVKGDSRTITTKGERGQPGIP GVHGMKGDDGVPGRDGLDGFPGLPGPPGDGIKGPPGDAGLPGTPGTKGFPGEVGPPGQGLPGPKGERGFP GDAGLPGPPGFPGPPGLPGTPGQADCDTGVKRPIGGGQQVVIQPGCVEGPAGSPGQPGPPGPTGAKGIRG IPGFPGASGEQGLKGFPGDPGREGFPGPPGFMGPRGSKGAPGLPGPDGPPGPIGLPGPAGPPGDRGIPGE VLGAQPGARGDAGLPGQPGLKGFPGEIGAPGFRGSQGMPGMPGLKGQPGFPGPSGQPGLSGPPGQHGFPG APGREGPLGLPGSPGLGGLPGDRGEPGEPGEPGPVGMKGVSGDRGDAGVSGERGHPGSPGFKGMAGMPGI PGQKGDRGSPGMDGFQGMLGLKGRPGFPGIKGEAGFFGVPGLKGLPGEPGVKGNRGDRGPPGPPPLILPG MKDIKGEKGDEGPMGLKGYLGLKGIQGMPGVPGLSGIPGLPGRPGFIKGAKGDIGVPGTPGLPGFPGVSG PPGITGFPGFTGSRGEKGTPGVAGVFGETGPTGDFGDIGDTVDLPGSPGLKGERGVTGIPGLKGLFGEKG AEGDVGFPGITGMAGAQGSPGLKGQTGFPGLTGLQGPQGEPGRIGIPGDKGDFGWPGVPGRPGIPGIRGI SGLHGLPGTKGFPGSPGVDAHGDPGFPGPTGDRGDRGEANTLPGPVGAPGQKGEQGIPGERGPVGSPGLQ GFPGISPPSNISGLPGDVGAPGIFGLQGYQGPPGPPGPNALPGIKGDEGSSGAAGFPGEKGWVGDPGPQG QPGVHGLPGEKGPKGEQGFMGNTGPSGAVGDRGPKGPKGDQGFPGAPGSMGSPGIPGIPQKIAVQPGTMG PQGRRGLPGALGEMGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPIGQEGEPGRPGS PGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMP FLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEEEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAG WRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYFANKYSFWLTTIPEQNFQ STPSADTLKAGLIRTHISRCQVCMKNL >XP_038287383.1 collagen alpha-2(IV) chain isoform X1 [Canis lupus familiaris] MDRPRCSAHSPALRRWLLLGAVTVGLLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQG YTGPPGLQGFPGLQGRKGDKGERGSPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGPPGYDGCNGT RGDVGRQGPEGPAGFLGPPGPQGPKGQKGEPYALSSVDRDKYRGEPGEPGLVGFQGPPGRPGPIGQMGPV GAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDMGLPGPNGIPSDTHHAIIGPMKEMFHPDQYKGEKGS EGEPGRKGISLKGEEGIMGFSGTRGAPGYDGEKGSPGQKGSRGLDGYQGPDGPPGPKGEAGDRGPPGAPA YFPHPSQVKGARGDPGFPGTHGDPGSRGEPGDPGPPGLPGPSIRDEDGKRGLPGEMGPKGFIGDPGIPAP YPGPPGTDGKPGLRGPPGAAGPPGPDGFLFGLKGTEGSAGFPGPSGFPGARGQKGWKGDAGDCKCAEGDQ FVGGLPGLPGPKGFPGINGEPGRKGSQGDPGQHGIPGFPGFKGAPGTVGPPGPKGLKGDSRAITTKGERG QPGVPGVPGLKGDDGVPGRDGLDGFPGLPGPPGDGIKGPPGDSGYPGAPGTKGAPGERGPPGLGLPGPKG ERGFPGDAGLPGPPGFPGPPGPPGTPGQIDCDTGVKRPIGGDGQEAVQPDCVRGPMGSPGLPGPPGPTGA KGLQGIPGLSGADGTPGLRGLPGDPGREGFPGPPGFVGPRGSKGAVGLPGPDGHPGPTGLPGPVGPPGDR GLPGEVLGAQPGPRGDAGLPGHPGLKGPPGERGPPGFRGSQGMPGMPGLKGQPGFPGPSGQPGLPGPPGQ HGFPGAPGREGPLGLPGASGRGGLPGDRGDPGDTGVPGPVGMKGLSGDRGDPGLLGERGPPGSPGFKGMS GMPGIPGQKGGRGSPGMDGFQGMVGLKGRPGLPGNKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPP IIQPGMKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGVPGLPGKPGHIKGIKGDIGIPGVPGLPGF PGVPGPPGIIGFPGFTGSRGDKGAPGRAGLYGEVGPTGDFGDSGDIINLPGSPGLKGERGIAGAPGLKGF FGEKGTEGEVGFPGITGVPGVQGPPGPKGQTGFPGLTGLQGPQGDPGRAGVPGNKGDYGWPGIPGSPGFP GIRGISGLHGLPGTKGLPGSPGADIHGDPGFPGPAGDRGDPGEANIRPGPIGAPGQKGERGDPGGRGPIG SPGLQGFPGITPPSNMSGLPGDKGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGNPGAPGTPGTKGWGGD PGPQGRPGVFGLPGEKGPRGEPGFMGNTGATGSVGDRGPKGPKGDRGLPGAPGSVGSPGIAGIPQKITIQ PGPVGPQGRRGPPGMQGEMGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPVGQEGEP GRPGTPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLAR FSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDDIKPYISRCSVCEAPAVAIAVHSQDVSIP HCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIP EQSFQGSPSADTLKAGLIRTHISRCQVCMKNL >NP_001155862.1 collagen alpha-2(IV) chain precursor [Gallus gallus] MDLSPLPGARVSVCQDVGLLLVLLEVVLSAGRVDAGGKSYTGPCGGRDCSGGCQCFPEKGARGQPGILGS QGFPGPPGLMGIPGLQGPKGHKGERGHPGISGPKGETGQRGVTGFPGADGVPGHPGQPGSRGKPGHDGCN GTVGDPGDPGTPGHSGFPGTIGVQGPKGQKGEPYVLPPDIASRHRGDPGDPGFTGFPGAPGTLGIQGPIG PRGVPGRPGPPGSPGPQGPQGNRGLGFYGEKGEQGSPGPPGPPGLPTRELIGVPTDKHKGERGEPGQKGE AGFPGVLLFAPEKGEEGVMGFPGQRGLPGNDGFPGLSGERGFPGFDGQPGQYGPRGGKGEQGEMGPPGPP AYVPYRIPRKGVRGDPGSPGASGLRGEQGEQGDRGLPGIPGFSDGDADKPGLPGEIGPKGEKGEEGSPAY QAGPPGFPGKHGEPGIRGPPGPPGTPGSLFGLKGQEGTPGRPGVQGFPGPRGQRGPKGEEGDCSKCLLSD ELRRGSTGPRGPPGFPGTPGQPGRKGEPGDQGPHGIPGYAGAKGQSGQEGLPGPKGEKGDSIYITTKGTK GIRGDPGLPGIRGEDGFPGRDGLDGLPGLPGLPGDGIRGLPGDPGYPGELGPKGFPGEIGLPGEGYPGPK GYRGLPGDRGTDGHPGPPGLPGPPGEPGQLDCGQVIEDFSRGEATDPIWSGGGCVRPPKGSQGNPGLPGA TGTKGARGFPGDPGPVGFPGLNGTRGDPGREGYPGPPGFIGPRGDRGPNGLPGLQGHPGLMGKSGAPGLA GQKGAPGDVLGAAAGPRGDDGLPGFPGLKGAPGDQGIPGIRGADGNPGLPGPKGDPGLQGLPGLMGLPGT PGTHGFPGPPGNRGPDGGPGSQGPLGPPGARGEDGEQGFPGPVGMKGLSGDKGETGFPGLQGIPGVTGPP GISGMDGFPGDKGSRGSPGIDGFKGMPGLKGRPGIKGIKGEFGLLGTRGDKGAQGARGFKGDRGEQGPPG EPPKLKPSMMMEVKGEKGDAGETGTKGFFGIKGSKGMPGLPGKTGIPGSPGHPSYVPGVKGDIGAKGLTG LKGYPGPTGSPGIRGFPGSTGGRGDKGAPGISGHFGTPGSHGEIGEPGDTINLPGMPGLKGEVGVPGLTG LRGGPGQKGEGGDPGLPGIEGLKGIQGVPGSLGQKGLPGLVGPPGQQGSPGTPGFQGEKGAPGWPGLPGQ AGLPGLRGISGLHGLPGTKGLPGSPGPDGYGSAGFPGPVGDKGEAGEPSRVEGSQGPPGQKGDRGVPGVQ GPFGIPGQDGLPGPPGISNISGYPGDTGSPGLDGVPGYPGLHGQPGIPAPPGSKGESGRAGVSGQAGPKG TRGDPGLPGRPGIPGYPGPKGRKGEQGVIGFIGTVGFPGDLGPIGPKGDRGLTGFQGPPGSPGLPPIPPR LVAEQGSPGPRGNAGPRGSPGDAGPQGPPGEPGLRGLPGEPGLQGRGGIPAPPGSRGEQGAMGFQGPVGF EGQPGRPGSPGLPGMPGRSVSIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGS CLARFSTMPFLYCNPGDICYYANRNDKSYWLSTTAPLPMMPVAEEEIRPYISRCSVCEAPAVAIAVHSQE ASIPRCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYFANKYSFWL TTIDQPFQSKPSADTLKAGLIRSHISRCQVCMKNL >XP_024204109.1 collagen alpha-2(IV) chain isoform X1 [Pan troglodytes] MGRDQRAVAGPALRRWLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGY NGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQ GDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVG APGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDLLHPIIAPTGVTFHPDQYKGEKGSE GEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAY SPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGAPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALY GGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEA IKGLPGLPGPKGFAGINGEPGRKGDKGDPGQHGLPGFPGLKGVPGNVGAPGPKGAKGDSRTITTKGERGQ PGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQ RGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAIGGDRQEAIQPGCVGGPKGLPGLPGPPGPTGAK GLRGIPGFSGADGGPGPKGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERG LPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLH GFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGERGHPGSPGFKGIDG MPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPV ILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGAPGIPGLPGFP GVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFF GEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGEPGRIGLPGGKGDDGWPGAPGLPGFPG LRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGS PGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDS GPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQP GTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPG RLLSLFLGLQVHQAVHSLSLSGCRCTRLSTFSLSQAAGAPGRPLSLSRAVGAPGHPLSLFLGLQVHQAVH FLSLSGCRCTRPSTHSLSRAAGTPGCPLCLSLSRAAGAPGRPLSLFLGLQVHQAVHSLSFSGCRCTRPST HSLSRAAGTPGCPLCLSLSRAAGAPGRPLSLSLSGCRCTRPSTLSLSRAAGAPGRPGSPGLPGMPGRSVS IGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYY ASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLM HTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPEQSFQGSPSADTLKAGL IRTHISRCQVCMKNL >XP_024855939.1 collagen alpha-2(IV) chain [Bos taurus] MDRELRAAARPALRRWLLLGAVTVGLLAQSVLAGVKKLDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQG YTGPPGLQGFPGLQGRKGDKGQRGAPGITGPKGDVGPRGVSGFPGADGIPGHPGQGGPRGPPGYDGCNGT VGDSGYAGPPGPGGFLGPRGPQGPKGQKGEPYALSSEDRDKYRGEPGEPGLVGLQGPPGRPGPVGQMGPV GAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDMGLQGPGGIPPDNGYVEKPTPVYELLPEQYKGEKGS QGEPGRIGVSLKGEEGVVGFSGPRGAPGIDSEKGLPGQKGSRGLDGYQGPDGLPGPKGERGDPGPPGPPA YSPYPSVAKGVRGEPGSPGAPGEPGDRGVPGDPGLPGRPGTTIGDEDEKRGLPGEMGPKGFTGEQGFPAL YPGPPGTDGQPGLRGPPGLPGPPGPDGFLFGLKGEKGSGGFPGSSGFPGARGQKGWKGDAGDCKCADQFI RGPPGLPGPKGFAGANGQPGSKGSQGDPGQHGVPGFAGFKGAPGNVGPPGPKGMKGDSRTITTKGERGQP GVPGAPGLKGSDGIPGPPGLDGFHGLPGPPGDGIKGPRGDTGQPGAPGTKGLPGERGPPGLGLPGPKGER GFPGDAGLPGPPGFPGPPGLPGSPGQIDCDSGVKRPIGADGQETIQPGCVGGPKGSPGQPGLPGPPGAKG LRGIPGFSGADGAPGLKGLPGDPGREGFPGPPGFMGPRGSKGAVGPPGLDGLPGASGLPGPVGPPGDRGL PGEVLGAQPGPRGDSGLPGRPGPKGPPGERGPPGFRGSQGMPGMPGQKGQPGSPGLSGQPGLPGPPGQHG FPGAPGREGPLGPPGAPGFQGLPGDRGEPGDTGVPGPVGMKGGSGDRGDPGQQGERGHPGHPGFKGVSGM PGAPGLKGARGSPGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPLI EPGMKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGIPGLPGRPGQIKGVKGDTGIPGVPGSPGFPG VPGSPGIMGFQGFTGSRGDKGVPGRAGLFGEVGPTGDFGDIGDTIDLPGSPGLKGERGTTGIPGQKGFFG ERGTEGDIGFPGITGLAGVQGPPGFKGQKGFPGLTGLQGPQGDPGRAGAPGIKGDSGWPGNPGLPGLPGL RGISGLHGLPGSKGFPGSPGADVHGDPGFPGPAGDKGDPGEPNTLPGPTGAPGQKGERGAPGERGPIGSP GLQGFPGITPLSNISGSPGDVGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGSPGTKGWIGDPG PQGRPGVFGLPGEKGPKGEPGFMGNIGPTGSPGDRGPKGPKGDRGLPGAPGAVGTPGITGIPQRIAIERG PVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGVSAIPGFRGDQGPVGLQGPVGFEGEPGR PGSPGLPGMPGRSISIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFS TMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEEDIRPYISRCSVCEAPAVAIAVHSQDVSIPHC PAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIPEQ SFQGTPSADTLKAGLIRTHISRCQVCMKNL >XP_020921567.1 collagen alpha-2(IV) chain [Sus scrofa] MDRDPRAASGPALRRWLLLGTVMVGLLAQSVLAGVKKLDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQG YTGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGSDGCNGT VGDTGYAGPVGPDGFLGPPGPQGPKGQKGEPYALSREDRDKYRGEPGEPGLVGFQGPPGRPGPVGQMGPV GAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDVGQPGPNGIPSDNHHPIIGPTRETIYLDQYKGEKGS EGEPGRKGISLKGEEGIMGFSGSRGVPGFDGEKGSPGQKGSRGLDGYEGPDGYPGPKGERGDPGPPGAPA YSPHPSLAKGARGEPGFPGALGEPGARGEPGDPGPPGLPGTSVRDEDEKRGLPGEMGPKGYAGEPGAPAL YPGPPGADGKPGLRGPPGPPGPPGPDDFLFGLKGAKGSMGYPGPSGFPGARGQKGWKGDAGDCKCAEDDQ FVGGLPGPPGPKGFPGINGEPGRKGSQGDPGQHGIPGFPGFKGAPGDAGPPGPKGMKGDSRTITTKGERG QPGVPGVPGLRGDDGAPGRDGLDGFPGLPGPPGDGIKGPPGDAGHPGVPGTKGLAGDRGPPGLGLPGPKG ERGFPGDDGLPGPPGFPGPPGPPGPPGQIDCDSGVKRPIGADGQEVIQPGCVGGPKGSPGQPGPPGPPGA KGLRGIPGPSGADGAPGLKGFPGDPGREGFPGPPGFVGPRGSKGAVGPPGLDGLPGPSGLPGPVGPPGDK GLPGEVLGAQPGSRGDPGLPGHPGLKGPPGERGAPGFRGSEGMPGMPGLKGQPGFPGPSGQPGLPGPPGQ HGFPGAPGREGPLGPPGAPGFGGLPGDRGDPGDTGVPGPVGMKGLSGDRGDPGLLGERGHPGSPGFKGVA GMPGAPGPKGTRGSPGMHGFQGMLGLKGSPGLPGSKGEAGFFGVPGLKGLPGEPGVKGSRGDPGLPGPPP TILPGMKDIKGEKGDEGPMGLKGYLGLKGIPGMPGIPGLSGVPGLPGKPGHVKGAKGDTGAPGVPGSPGF PGLPGPPGIIGFPGFTGSRGDKGSPGRAGLYGEIGATGDFGDIGDTIDLPGSPGLKGERGTAGVPGLKGF FGEKGTVGDVGFPGITGLAGVQGPPGLKGQTGFPGLTGLQGPQGDPGRAGVPGAKGELGWPGNVGLPGLP GIRGISGLHGLPGTKGFPGSPGADVHGDPGFPGPAGDRGDPGEANTLPGPAGAPGQKGERGAPGERGPVG NPGLQGFPGITPPSNVSGLPGDTGAPGIFGPEGYRGPPGPPGPAALPGSKGDEGLPGIPGNPGGKGWVGD PGPQGRPGVFGLPGEKGPRGEQGFMGNTGATGSVGDRGPKGPKGDRGLPGPPGAVGAPGIVGIPQRIAVQ RGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPVGQQGPVGQEGEP GRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLAR FSTMPFLYCNPGDICHYASRNDKSYWLSTTAPLPMMPVAEEEIRPYISRCSVCEAPAVAIAVHSQDVSIP HCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIP EQSFQSSPSADTLKAGLIRTHISRCQVCMKNL >XP_008258402.1 PREDICTED: collagen alpha-2(IV) chain [Oryctolagus cuniculus] MGRERRAASGSAMRRWLLLGAVTAGFLAQSVLAGVKKSDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQG YTGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGPPGYDGCNGT RGDEGPQGPSGTGGFPGSPGPPRTQRGRRVSPYALSEEDRDRYRGEIGEPGLVGFQGPPGRPGPMGPMGP VGAPGRPGPPGPPGPKGHPGNRGLGFYGKKGEKGDIGAPGPNGIPFDTIYPIVGPTKTTFHPDQYKGEKG SEGEPGAIGISLKGEEGIMGFSGSRGAPGLDGEKGSPGQKGSRGVDGYQGPDGPRGPKGQAGDPGPAGPP AYSPHPSLAKGARGDPGFPGPHGDPGSRGEPGDPGPPGSPGLPVRDEDEMRGLPGEMGPKGFAGEKGFPA LYPGPPGVDGKPGLPGVPGPAGPPGPDGFLFGLKGAEGRVGYPGPSGFPGARGQKGWKGEAGDCKCLEGD QFPGGLPGLPGPKGVPGLNGEPGSKGQQGDPGQHGIPGFPGFKGAPGLTGVPGPKGAKGDSRTITTKGER GQPGVPGVPGMKGDDGVPGRDGLDGFPGLPGPPGDGIRGPPGDAGYPGIPGTKGGPGDVGPPGLGLPGPK GERGFPGDAGLPGPPGFPGPPGPPGTPGQIDCDTGVKRPPGGDGQEAVLPGCAAGPKGLPGPPGPPGPPG AKGLQGIPGFSGADGPPGLKGLPGDPGREGFPGPPGFVGPRGSKGATGLPGPDGRPGPVGLPGPAGAPGD RGLPGEVLGAQPGPRGDAGLPGQPGLKGLPGERGPPGFTGSQGMPGMPGLKGQLGLPGPSGQQGLQGPPG QHGFPGAPGPAGPLGLPGAPGLEGLPGDRGEPGDTGVPGPVGMKGLSGDRGDAGFSGERGQPGNPGFKGM SGMPGTPGPKGERGSPGMDGFQGMLGLKGRPGLPGTKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPP PIILPGMKDIKGEKGDEGPMGLKGHLGLKGIQGNSRGVPWPGGNPWGCLGRPGHIKRSRKAKLAVPGVPG LPGRAGVRGPSGHGAWPGIRGTRGDKGAPGIAGLYGELGPTGDFGDVGDTIDLPGSPGLKGEQGSAGVPG LKGFFGEKGVEGEVGFPGITGLTGAQGPPGLKGQTGFPGLTGLQGPQGDPGRIGVPGDKGDRGWPGAPGL PGFPGIRGIGGLHGLPGTKGFQGSPGADAHGDPGFPGATGERGDPGEANLLPGPLGVPGQKGERGVPGER GPAGSPGLQGFPGITPPSNISGLPGDKGAAGIFGLQGYRGPPGPPGPAALPGSKGEDGSPGAAGVPGSKG WAGDPGPQGRPGVFGLPGEKGPRGEQGFMGNTGATGAAGDRGPKGPKGDQGFPGAPGPVGSPGIIGLPPE DRCPARGLWAPRERGGPPGAQGEIGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPVG QEGEPGRPGSPGLPGMPGRSVSIGYLLVKHSQTEQEPMCPLGMNKLWSGYSLLYFEGQEKAHNQDLGLAG SCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAVAIAVHSQ DVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFW LTTIPERSFQGSPSADTLKAGLIRTHISRCQVCMKNL >XP_024086739.1 collagen alpha-2(IV) chain [Pongo abelii] MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQG YNGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGT QGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGYVGQMGPV GAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTRVTFHPDQYKGEKGS EGEPGIRGISLKGEEGIMGFPGPRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGPPA YSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPAL YGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAEGGVGFPGLPGSPGARGPKGWKGDAGDCRCTEGDE AIRGLPGLPGPKGFAGINGEPGTKGDKGDPGQHGLPGFPGLKGVPGNVGAPGPKGAKGDSRTITTKGERG QPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKG QRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAIGGDRQEVIQPGCIGGPKGLPGLPGPPGPTGT KGLRGIPGFSGADGGPGPKGLPGDPGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGER GLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGSPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGL HGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGERGHPGSPGFKGID GMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPP VILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGAPGIPGLPGF PGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGPTGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGF FGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGESGRIGLPGGKGDDGWPGAPGLPGFP GLRGIRGLHGLPGTKGFPGSPGADIHGDPGFPGPPGERGEPGEANTLPGPVGVPGQKGDQGAPGERGPPG SPGLQGFPGITPPSNISGVPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGD AGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQ PGTVGPQGRRGHPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAP GRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLAR FSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAVAIAVHSQDVSIP HCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIP EQSFQGSPSADTLKAGLIRTHISRCQVCMKNL >XP_010726857.1 collagen alpha-2(IV) chain [Meleagris gallopavo] MDLSPLPGARVFVCQDAGLLLVLLEVVLLAGRVDAGGKSYTGPCGGRDCSGGCQCFPEKGARGQPGNLGS QGLPGPPGLMGIPGLQGPKGHKGERGHPGISGPKGEMGLRGVTGFPGADGIPGHPGQPGSRGKPGHDGCN GTVGDPGDPGTPGHSGFPGTIGVQGPKGQKGEPYVLPPDIASQYRGEPGDPGLTGFPGAPGRLGIQGPIG PRGTPGRPGPPGPPGPQGPQGNRGLGFYGEKGEQGSPGPPGPPGLPTRELIGVPTDKHKGERGEPGLKGE AGFPGVLLFTPEKGEEGVMGFPGQRGLPGNDGFPGLSGERGFPGFDGQPGQYGPRGGKGEQGEMGPPGPP AYVPYRIPRKGVRGDPGFPGASGLQGEPGEQGDRGLPGIPGFSDGDADKPGLPGEIGPKGEKGEEGSPAY QAGPPGFPGKHGEPGPRGPPGPPGTPGSLFGLKGQEGTPGRPGAQGFPGPRGQRGPKGEEGDCSKCLLSD ELRRGSTGPRGPPGFPGTPGQPGRKGEPGDQGPHGIPGYAGAKGQSGQEGFPGPKGEKGDSIYITTKGTK GIRGDPGLPGIRGEDGFPGRDGLDGLPGLPGLPGDGIRGLPGDPGYPGELGPKGFPGETGLPGGGFPGPK GYRGPPGDHGTQGNPGIPGLPGPPGEPGQIDCGQVIEDFPRGDATDPIWSGGGCVRPPKGSQGNPGLPGA TGTKGARGFPGDPGPVGFPGLNGTRGDPGREGYPGPPGFIGPRGDSGPNGLPGLQGHPGLMGKSGAPGLD GQKGAPGDVLGAAAGPQGDAGLPGFPGLKGAPGDQGIPGIRGADGNPGLPGPKGDPGLQGLPGLMGLPGT PGTHGFPGPPGNPGPDGGPGSQGPLGPPGARGEDGEQGFPGLVGMKGQSGDKGETGFPGLQGIPGVTGPP GISGMDGFPGDKGSRGSPGIDGFKGMPGLKGRPGIKGIKGEFGLYGTRGDKGTKGAQGFKGDRGERGPPG EPPKPKPSMMMKVKGEKGDAGETGTKGFFGIKGSKGMPGLPGKTGIPGSPGHPSYVPGVKGDIGAKGLTG LKGYPGPTGSPGIRGFPGSTGGRGDKGAPGSSGHFGTPGSHGEIGEPGDTINLPGMPGLKGEVGVPGLTG LRGGPGQKGEGGDPGLPGIEGLKGIQGVPGSLGQQGLPGLVGPPGQQGSPGTPGFQGEKGTPGWPGLPGQ AGLPGLRGIGGLHGLPGTKGLPGSPGPDGYGSAGFPGPVGDKGEAGEPSRVQGSQGPPGQKGDRGVPGIQ GPFGIPGQDGLPGLPGFSNISGYPGDIGSPGLDGVPGYPGLHGQPGIPAPPGSKGESGRAGVSGQAGPKG TRGDPGLQGRPGIPGYPGPKGRKGEQGVIGFIGTVGFPGDLGPIGPKGDRGLTGFQGPPGSPGLPPLPPR LVAEQGSPGPRGSAGPQGSPGDIGPQGPPGEPGFRGLPGEPGLQGRGGIPAPPGSRGEQGAMGFQGPVGF EGQPGRPGSPGLPGMPGRSVSIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGS CLARFSTMPFLYCNPGDICYYANRNDKSYWLSTTAPLPMMPVAEEEIRPYISRCSVCEAPAVAIAVHSQE ASIPRCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYFANKYSFWL TTIDQPFQSKPSADTLKAGLIRSHISRCQVCMKNL >XP_034792866.1 collagen alpha-2(IV) chain [Pan paniscus] MGRDQRAVAGPALRRWLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGY NGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQ GDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVG APGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDLLHPIIAPTGVTFHPDQYKGEKGSE GEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAY SPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGAPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALY GGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEA IKGLPGLPGPKGFAGINGEPGRKGDKGDPGQHGLPGFPGLKGVPGNVGAPGPKGAKGDSRTITTKGERGQ PGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQ RGFPGDAGLPGPPGFLGPPGPTGTPGQIDCDTDVKRAVGGDRQEAIQPGCVGGPKGLPGLPGPPGPTGAK GLRGIPGFSGADGGPGPKGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERG LPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLH GFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGERGHPGSPGFKGIDG MPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPV ILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGAPGIPGLPGFP GVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFF GEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGEPGRIGLPGGKGDDGWPGAPGLPGFPG LRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGS PGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDS GPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQP GTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPG RPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARF STMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAVAIAVHSQDVSIPH CPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPE QSFQGSPSADTLKAGLIRTHISRCQVCMKNL >XP_023108926.1 collagen alpha-2(IV) chain [Felis catus] MDRHQCSVSSPALRRWLLLGAVTVGVLAQSVLAGVKKFDVPCGGRDCSGGCQCFPEKGGRGQPGPVGPQG YTGPPGLQGFPGLQGRKGDKGERGSPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGPPGHDGCNGT RGDVGRQGPVGPGGFAGPPGPQGPKGQKGEPYALSSVDRDKYRGEPGEPGLVGFQGPPGRHGPVGQMGPV GAPGRPGPPGPPGPKGQPGNRGLGFYGQKGEKGDMGQPGPNGIPSDIHHAIIGPMKEMFHPDQYKGEKGS EGEPGRKGIALKGEEGVMGFSGIRGSPGFDGEKGSPGQKGSKGLDGYQGPDGPPGLKGEVGDRGPPGAPA YSPHPSLAKGVRGDPGFPGAHGEPGSRGEPGDPGPPGPPGTSIGDEDGKRGLPGEMGPKGFIGDPGIPAL YPGPPGTDGKPGPRGPPGPPGLPGPDGFLFGLKGAEGNVGYPGPSGFPGARGQKGWKGDAGDCKCAEGDQ FIGGLPGPPGPKGLPGVNGEPGKKGSQGDPGQHGIPGFPGFKGAPGNVGPPGPKGVKGDSRAITTKGERG QPGVPGVPGLKGDDGVPGRDGLDGFPGLPGPPGDGITGPPGDIGYPGTPGTKGAPGERGPPGLGLPGPKG ERGFPGDVGPPGPPGFPGPAGPPGAPGQIDCDTGVKRPIGDDGQKTVRPDCVGGPKGAPGLRGPPGPTGA KGLPGIPGPSGADGVPGLKGLPGDPGREGFPGPPGFVGPRGSKGVVGLRGPDGHPGPTGLPGPVGPPGDR GLPGEVLGAQPGPRGDAGLPGHPGLKGPPGERGPPGFRGSQGMPGMPGLKGQPGFPGPSGQPGLPGPPGL HGFPGAPGQEGPLGLPGAPGRGGLPGDRGDPGDIGIPGPVGMKGLSGDRGDPGLLGERGPPGGPGFKGMS GIPGVPGPKGSRGSPGMDGFQGMVGLKGRAGLPGNKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPP IIQPGMKDIKGEKGDEGPMGLKGYLGLKGVPGMPGIPGLSGIPGLPGKPGHIKGVKGDIGVPGVPGLPGF PGVPGPPGIIGFPGFTGSRGDKGAPGRAGLYGEVGPTGDFGDIGDTIDLPGSPGLKGERGIAGAPGLKGF FGEKGTEGEVGFPGITGVPGVQGPPGPKGQAGFPGLTGLQGPQGEPGRAGAPGDKGDYGWPGIPGSPGFP GIRGISGLHGLPGTKGFPGSPGVDAHGDPGFPGPAGDRGDPGEANTRPGPVGAPGQKGERGNPGERGPVG SPGLQGFPGITPPSNISGSPGDKGAPGIFGPEGYRGPPGPPGPAALPGRKGDEGNPGAPGNPGTKGWGGD PGPQGRPGVFGLPGEKGPRGEPGLMGNTGATGSVGDPGPKGPKGDRGLPGAPGSVGSPGIVGIPQKITVQ PGPVGPHGRRGPPGAQGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGQQGPIGQEGEP GRPGTPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLAR FSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAVAIAVHSQDVSIP HCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIP ERSFQGSPSADTLKAGLIRTHISRCQVCMKNL >XP_027829588.1 collagen alpha-2(IV) chain isoform X1 [Ovis aries] MDRELRAAARPALRRWLLLGAVTVGLLAQSVLAGVKKLDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQG YTGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGPRGVSGFPGADGIPGHPGQGGPRGPPGYDGCNGT MGDSGYAGPPGPGGFLGPRGPQGPKGQKGEPYALSSEDRDKYRGEPGEPGLVGLQGPPGRPGPVGQMGPV GAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDMGLQGPGGIPPDNGYVEKPTPGYELLPEQYKGEKGS QGEPGRIGVSLKGEEGVMGFSGPRGAPGFDGEKGLPGQKGSRGLDGYQGPDGLPGPKGEMGNPGPPGLPA YSPHPSVAKGIRGEPGSPGAPGEPGARGEPGDPGLPGRPGTTIGDEDEKRGLPGEMGPKGFIGERGFPAL YPGPPGADGKPGLRGPPGRPGPPGPDGFLFGLKGARGSGGFPGSSGFPGARGQKGWKGDAGDCRCADQFI RGPPGLPGPKGFAGANGQPGSKGSQGDPGPHGLPGFSGFKGAPGNVGPPGPKGMKGDSRTITTKGERGQP GVPGVPGLKGTDGIPGPPGLDGFHGLPGPPGDGIKGPRGDAGQPGAPGTKGLPGERGPPGLGLPGLKGER GFPGDAGLPGPPGFPGPPGLPGAPGQTDCDSGVKRPIGADGQETIQPGCVGGPKGSPGQPGLPGPPGAKG LRGVPGFSGADGVPGLKGLPGDPGREGFPGPPGFMGPRGSKGAVGPPGLDGLPGASGLPGPVGPPGDRGL PGEVLGAQPGPRGDSGLPGRPGLKGPPGERGPPGFRGSQGMPGMPGQKGQPGSPGFSGQPGLPGAPGQHG FPGAPGREGPLGPPGAPGFEGLPGDRGEPGDTGVPGPVGRKGGSGDRGDPGQQGERGHPGLPGFKGVSGM PGTPGLKGARGSPGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPII LPGMKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGIPGLPGRPGHIKGVKGDTGVPGVPGSPGFPG VPGSPGVMGFQGFTGSRGDKGAPGRAGLFGEVGETGDFGDIGDTIDLPGSPGLKGERGTTGIPGQKGFLG ERGTEGDVGFPGITGLAGVQGPPGFQGQKGFPGLTGLQGPQGDPGRAGAPGIKGDSGWPGNPGLPGLPGL RGISGLHGLPGNKGFPGSPGADVHGDPGFPGPAGDKGDPGEANTLPGPTGAPGQKGERGAPGERGPIGSP GLQGFPGITPPSNISGSPGDIGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGIKGWVGDPG PQGRPGVFGLPGEKGPKGEPGFMGNIGPTGSPGDRGPRGPKGDRGLPGAPGAVGAPGIAGIPQRIAVERG PVGPQGRRGPPGAQGEMGPQGPPGEPGFRGVQGKAGPQGRGGVSAVPGFRGDQGPVGLQGPVGFEGEPGR PGSPGLPGMPGRSISIGYLLVKHSQTEKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFS TMPFLYCNPGDICYYASRNDKSYWLSTTAPLPMMPVAEEDIRPYISRCSVCEAPAVAIAVHSQDVSIPHC PAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIPEQ NFQGTPSADTLKAGLIRTHISRCQVCMKNL >XP_004054779.3 collagen alpha-2(IV) chain [Gorilla gorilla gorilla] MGRDQRALAGPALRRWLLLGTVTMGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQG YNGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGT QGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPV GAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGS EGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPA YSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPAL YGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDE AIKGLPGLPGPKGFAGINGEPGRKGDKGDPGQHGLPGFPGLKGVPGNVGAPGPKGAKGDSRAITTKGERG QPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKG QRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKKAIGGDRQEAIQPGCVGGPKGLPGLPGPPGPTGA KGLRGIPGFSGADGGPGPKGLPGDAGREGFPGPPGFTGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGER GLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGL HGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGERGHPGSPGFKGID GMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPP VILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGAPGIPGLPGF PGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGTTGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGF FGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGEPGRIGLPGGKGDDGWPGAPGLPGFP GLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPLGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPG SPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGD SGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGERGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQ PGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVTAVPGFRGDEGPIGHQGPIGQEGAP GRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLAR FSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAVAIAVHSQDVSIP HCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIP EQSFQGSPSADTLKAGLIRTHISRCQVCMKNL >XP_011488241.1 collagen alpha-2(IV) chain isoform X1 [Oryzias latipes] MRHCGQRNLWLPLLCVYIVILTSGVQAGGKKHSGPCGGRDCSGGCKCFPEKGGRGQPGPLGPQGPQGPKG RPGDLGIQGQKGQKGDQGPGGVIGPKGSAGMTGVPGFTGNDGIPGHPGQGGPRGKPGADGCNGTKGEPGI PGIPGDYGIQGAAGSPGRKGEKGDNLDVKVYMQRFRGDQGAPGFDGPFGPDGPKGGEGTRGPTGPKGPPG PSGPPGPKGTMTKVLKGVKGEQGDVGQPGPPGNDTRQQIKPPSGPPGEKGQKGQVGEVDIITGEPGIPGP PGPRGEMGRNGQPGLEGEFGERGPTGIDGVKGVRGEPGVLILSGDPWSSGVGAPGPPGEQGPLGERGPVG DQGIPGRPGPPAYKTQQEVYTFGPLGFKGEQGDKGRQGEPGFPAFRAGPPGADGRPGDRGPPGPTITWAE YYKGPPGPRGRPGTAGLKGPKGDHGDCECRDLNARRGLPGPSGQHGDPGMIGEFGREGDFGDPGPRGVDG FPGSPGLPGPLGIKGRKGDITFATEKGFPGDSGDPGMDGFPGQLGTPGLHGRPGPPGFPGPPGEGPWGEP GDKGFPGRSGRPGVRGISGEPGQVFPGQKGLQGLPGDDGLPGYDGVPGPPGTPGGCSPTSGGLGDVTGLC DTLPGLPGAPGLPGSPGLPGFPGTQGLKGPQGFDGVGGEKGEQGDRGNGGSPGPAGFVGQRGDIGIPGAK GLVGSPGVPGAHGRYGPKGEKGVHGEILGASAGPQGDPGLPGLQGLKGQDGEPGLPGYEGMGGMPGMIGF KGEKGSLGLSGEEGKPGIAGLYGFPGEPGTAGPPGPSGATGDPGLPGERGTDGDPGPPGPVGLKGMPGEF GEDGSPGEPGSPGDPGWPGTTGRPGPPGIKGGKGSSGMVGFDGKKGTPGLKGIIGVKGDAGLPGEQGLKG TMGVPGEKGDRGVKGPPGEKPQIPLHIIVDMKGVKGEHGSQGNPGFTGPRGSKGLPGVPGFDGVHGSPGD PSNDKGQLGDPGLQGLPGIKGMPGPTGNRGVTGFEGMSGEKGIKGSAGAYGASGENGRKGAKGDAGPRID LPGSPGLRGEVGLPGNPGLKGLFGSPGDQGGSGFDGIVGIKGIFGDPGIQGFPGSDGQKGAPGYQGQKGF SGLPGKDGLPGFPGFPGVKGYPGLKGLHGLHGLKGQKGISGTAGLNFPGQAGNPGVKGQKGESGNPNDQQ GDSGIPGFKGFQGPTGEYGLPGLPGLRGPSGPDGIPNEPGSPGDPGFQGPAGFQGLPGARGVPGSDASPG QRGEPGLNGFPGFPGNQGFRGDPGPTGFRGPHGIFGKKGVKGEQGLMGIPGTTGPKGERGQTGFKGNTGL PGFPGQPGSQGPPPIPIRVPGERGPSGPRGLQGPLGIRGEPGPQGPPGDTGFIGPIGQKGMPGVSGTPGT PGFRGNFGQMGHPGLEGMEGNRGNPGIPGIPGMPGRSISVGYLLVKHSQSEEKPMCPVGMSKLWDGYSLL YFEGQEKAHNQDLGLAGSCLPRFSTMPFLYCNPGDICYYASRNDKSYWLSTTAPLPMMPVEENEIKPYIS RCSVCEAPSVAIAIHSQGIDIPQCPAGWRSLWIGYSFLMHTAAGNEGGGQSLSSPGSCLEDFRTLPFIEC NGAKGTCHYFANKHSFWLTSIDHSFHANPAPETLKAGQLRSRISRCQVCMKNL >XP_021152299.1 collagen alpha-2(IV) chain [Columba livia] MDISQLPSARIFVCQDLGLLLILMEVVLSAVKVDAGGKTYTGPCGGRDCSGGCQCFPEKGSRGQPGLLGS QGFTGPPGLMGIPGLQGPKGHKGERGHPGIAGPKGEVGQRGVTGLSYLIFEKSPTGHPGQPGSRGKPGHD GCNGTAGDPGDPGTPGVFGFPGTIGVQGPKGQKGEPYILPPDIASRYRGDPGEPGFNGFQGPPGTLGIQG PVGPRGERGRPGPPGPPGPPGPQGNRGLGFYGEKGEQGPPGPPGPPGLPTRELMGVPSDKHKGERGEPGQ KGEAGTPGEVLYAEKGEEGVMGFPGQRGLPGINGFPGLSGERGFPGFDGPPGAYGPRGSKGEPGEIGPPG PVSYFPSGFPRKGARGDPGVPGVSGLQGDPGEEGDRGLPGLPGFSDADGDKPGLPGEMGPKGEKGEIGSP AYQAGPPGFPGKHGTPGLRGLPGPAGPPGALFGLKGQEGTPGRFGAQGFPGPRGQKGPKGEEGDCSHCLL TEEQRRGSTGSPGPPGFPGTPGQPGRKGEPGDQGPHGLPGYPGAKGFPGPHGFPGPKGEKGDSLYITTKG TKGIRGDPGLPGIRGEDGFPGRDGLDGLPGQPGLPGDVIRGFPGDPGYPGELGPKGFPGEPGLQGEGLPG PKGYRGPPGDHGQDGSPGPPGLPGLPGEPGQLDCGQVFEDFSRGDATEPIWSGAGCVRPPKGSQGKPGLP GATGEKGARGFPGDPGPVGYPGLNGTRGDPGREGLPGPPGFTGPRGDRGPNGLPGLQGHPGLTGKPGAQG VPGLKGLPGDVLGAPAGSRGDAGLPGFPGLKGLPGDQGVPGIRGADGNPGLPGAKGEPGPQGLPGLMGLP GIPGTRGFPGPPGNPGPDGGPGPQGPVGPPGARGEDGEQGVPGPIGLKGLAGDKGDMGYPGLQGRPGVPG PRGVSGMDGFPGDKGSRGSPGIEGFKGMTGLKGRPGIKGIKGEFGPLGAQGDKGAQGARGFKGDRGDQGP PGEPPKLKPSMMMEVKGEKGDVGERGTKGFFGLKGSKGMPGLPGKTGIPGSPGHPSYVAGAKGDVGAKGL AGLKGYPGPAGSPGIRGFPGSTGGRGEKGLPGISGQFGTPGVHGEIGEQEEIXXXXXLKGEVGVPGLTGA RGGTGQKGEGGDPGLPGIEGLKGTQGIPGSVGQEGLPGLVGAPGQQGSPGTPGFQGEKGTPGWPGLPGQP GLPGLRGISGLHGLPGTKGLPGSPGPDGYGSAGFPGAVGDKGDAGEPSRVEGSRGPPGQKGDRGVPAGIS NISGYPGDKGSPGLDGVPGYPGLQGQPGIPAPPGSKGESGQPGVSGQTGPKGSRGDPGPVGTPGVRGYPG PKGRKGEQGVIGFMGTVGFPGDLGPIGPKGDRGVTGFQGPPGSPGLPPLPPRLVAEQGSPGPRGNMGPQG SPGDMGPQGPPGDPGFRGSPGEPGLQGRGGIPAPPGSRGEQGATGFQGPVGFEGQPGRPGSPGLPGMPGR SVNMGYLLVKHSQSEQEPMCPTGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDI CYYASRNDKSYWLSTTAPLPMMPVAEEDIRPYISRCSVCEAPAVAIAVHSQEASIPHCPEGWRSLWIGYS FLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIDQPFQSKPSADTLKA GLIRSHISRCQVCMKNL >XP_017911852.1 PREDICTED: collagen alpha-2(IV) chain [Capra hircus] MDRELRAAARPALRRWLLLGAVTVGLLAQSVLAGVKKLDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQG YTGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGPRGVSGFPGADGIPGHPGQGGPRGPPGYDGCNGT MGDSGYAGPPGPGGFLGPRGPQGPKGQKGEPYALSSEDRDKYRGEPGEPGLVGLQGPPGRPGPVGQMGPV GAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDMGLQGPGGIPPDNGYVEKPTPGYELLPEQYKGEKGS EGEPGRMGVSLKGEEGVMGFSGPRGAPGFDGEKGLLGQKGSRGLDGYQGPDGLPGPKGEMGDPGPPGLPA YSPHPSVAKGVRGEPGSPGAPGEPGARGEPGDPGLPGQPGTTIGDEDEKRGLPGEMGPKGFTGERGFPAL YPGPPGADGKPGLRGPPGRPGPPGPDGFLFGLKGATGSGGFPGSSGFPGARGQKGWKGDAGDCKCADQFI RGPPGLPGPKGFAGANGQPGSKGSQGDPGPHGLPGFSGFKGAPGNVGPPGPKGMKGDSRTITTKGERGQP GVPGVPGLKGTDGIPGPPGLDGFHGLPGPPGDGIKGPRGDAGQPGAPGTKGLPGERGPPGLGLPGPKGER GFPGDAGLPGPPGFPGPPGLPGAPGQTDCDSGVKRPIGADGQETIQPGCVGGPKGSPGQPGLPGPPGAKG LRGVPGFSGADGVPGLKGLPGDPGREGFPGPPGFMGPRGSKGAVGPPGLDGLPGASGLPGPAGPPGDRGL PGEVLGAQPGPRGDSGLPGRPGLKGPPGERGPPGFRGSQGMPGMPGQKGQPGSPGFSGQPGLPGAPGQHG FPGAPGREGPLGPPGAPGFEGLPGDRGEPGDTGVPGPVGRKGGSGDRGDPGQQGERGHPGLPGFKGVSGM PGTPGLKGARGSPGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPII LPGMKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGIPGLPGRPGHIKGVKGDTGVPGVPGSPGFPG VPGSPGVMGFQGFTGSRGDKGAPGRAGLFGEVGETGDFGDIGDTIDLPGSPGLKGERGTTGIPGQKGFLG ERGTEGDVGFPGITGLAGVQGPPGFQGQKGFPGLTGLQGPQGDPGRAGAPGIKGDSGWPGNPGLPGLPGL RGISGLHGLPGNKGFPGSPGADVHGDPGFPGPAGDKGDPGEANTLPGPTGAPGQKGERGAPGERGPIGSP GLQGFPGITPPSNISGSPGDIGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGIKGWVGDPG PQGRPGVFGLPGEKGPKGEPGFMGNIGPTGSPGDRGPRGPKGDRGLPGAPGAVGAPGITGIPQRIAVERG PVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGVSAVPGFRGDQGPVGLQGPVGFEGEPGR PGSPGLPGMPGRSISIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFS TMPFLYCNPGDICYYASRNDKSYWLSTTAPLPMMPVAEEDIRPYISRCSVCEAPAVAIAVHSQDVSIPHC PAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIPEQ SFQGAPSADTLKAGLIRTHISRCQVCMKNL >XP_006017292.1 collagen alpha-2(IV) chain [Alligator sinensis] MTVQVLLLLMLTTLLTGRVQAGGKTYTGPCAGRDCSGGCQCFPEKGSRGQPGPLGPQGFPGPPGLIGIPG LEGPKGHKGERGQPGITGPKGDQGLRGVTGFPGADGVPGHPGQPGSRGKPGHDGCNGTTGDPGEQGIHGP PGQFGFIGAQGPKGQKGEPYVFPPEIADKYRGEMGEPGIKGFQGPQGEPGLVGFIGPKGRPGKPGLPGLP GPRGEKGNRGLGFYGVNGEKGERGSEGPPGLPSTGEFTTSTDFSIDHCKGQQGMKGEKGEPGISGSRASR AEKGEEGIMGFPGQRGLPGINGIPGPVGEAGPPGFYGSPGYDGPKGMKGEQGEKGIPGLPAYVPYPIPRK GVRGDQGVTGFPGPRGDLGEKGNPGIPGRPGTSDGLDGLDKRGLPGEMGPKGYKGEPGFSAPYPGIPGFP GQPGPKGFPGSAGPKGSSSISFGLKGCRGDPGAAGSRGFPGPRGDKGFKGETGDCKCTGSDEARKSSAGL PGPPGFQGPPGEPGRKGEPGDQGQHGIPGFPGAKGFPGETGYPGPRGQKGYSVYITTKGSKGDPGDPGLA GVQGDDGLSGRDGTDGFPGPTGLPGDGTRGLPGDPGFPGPPGVKGFPGDAGLPGVGLPGPKGFHGLPGDH GTYGKSGPPGPPGPPGDPAQLDCDQVPEDLSRGNGRGPIRPGAGCVRAPAGQPGKPGLPGSTGSKGAKGI PGDPGLDGLQGLKGFPGDPGQEGLPGPPGFHGPRGERGPSGLLGQQGDDGISGKPGLPGPDGPKGVAGEV LGASAGSIGDVGLPGLPGLKGPPGNQGVPGLQGAGGIPGSPGSKGEPGLQGPHGLIGLPGEPGSHGFPGI PGHQGPAGRGGITGHIGSPGARGDHGEQGFPGPVGMKGLSGDKGELGIPGVQGIPGKTGLPGIDGMHGLQ GYKGAKGSPGIEGFKGMTGNRGFQGHKGVKGEIGFFGISGLKGEQGNPGSKGDRGEQGEPGKPPKIDSGM LVEVKGEKGDSGQTGLKGDSGFKGLKGMPGLPGEPGFPGFPGQPSHVTGAKGDIGSKGVTGSLGYPGQPG SPGIRGFPGSTGIRGEKGTEGFTGLYGESGLPGESGAPGDTINLPGIPGLKGEVGTPGSSGVRGSPGEKG QRGDPGFSGIEGLKGSQGLPGIKGQSGFPGLVGPPGQQGDPGAPGLPGEKGTQGWPGFAGPTGLPGLRGI SGLDGLPGTKGLQGSPGLDDYGPSGFPGGPGDKGQVGDPSTLEGARGGPGQKGERGNQGERGPTGSPGLD GIPGPPGVSNISGIRGDVGSPGLYGVPGYKGEQGRRGIPSPPGSKGEIGQIGVVGEDGPKGTRGDPGLTG KPGILGSFGAKGQKGEQGVMGPVGTVGISGDTGPTGPKGNRGVTGIQGPPGSPGLTPLPSKTLAEVGLPG PHGQRGPQGIPGEIGPQGPLGDSGFRGAPGKQGLQGRSGIPALPGFRGDQGPQGHQGPSGSEGIPGRPGS PGLPGMPGRSVNIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMP FLYCNPGDVCYYANRNDKSYWLSTTAPLPMMPVAEEEIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPEG WRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIEEQFQS TPSADTLKAGLIRTHISRCQVCMKNL >XP_015821737.1 PREDICTED: collagen alpha-2(IV) chain isoform X1 [Nothobranchius furzeri] MQTQRSRGQRNQRLLLLCLSLTILYPGVDAGGKKHSGPCGGRDCSGGCQCFPEKGARGLPGPLGPQGFVG PVGRPGDPGIQGPKGQKGDQGIGGIVGPKGSMGMTGVPGFDGLDGIPGHPGQAGPRGRPGADGCNGTHGE SGLPGLPGFIGPPGTLGQQGRKGEKGDTLDIKVFMQRFRGDPGTPGSSGIFGPMGERGWEGNRGPIGPKG PPGPPGPPGPKGTMTKYLKGVKGEPGDIGPQGPPGNYTTQQRQPIPGQPGLKGDKGEIGALADNKGETGM MGNAGLRGDSGRDGLTGLRGDPGEPGPTGRDGTKGVRGDPGELISSGSWFTPDGPPGPPGETGPQGERGP IGDQGFPGPPGPPASDSQQQQVWDFFGPFGFTGDKGDKGQRGERGWPAVFAGPPGIDGRVGPIGPPGPKA SLEVLFAGDPGWRGQPGRGGLKGQKGDHGQCECKLGNFQRGLPGPAGDPGDAGIIGEFGREGDLGDTGPR GQDGLPGSPGTNGLQGPKGRKGNTTVATQKGLPGDPGEAGKDGPAGVPGSPGPDGLSGFPGNRGLPGEGP RGQHGDKGYPGRPGAPGAAGLRGVPGQDVTGIKGQRGLPGDDGISGYVGVPGTPGAPGGCSPTGEGGQVD VTGPCQPVPGPPGLPGVPGVSGPPGAQGLPGLKGAVGVAGAKGEKGEQGEQGTGGSSGPPGFPGPRGDHG VPGRKGSIGVPGFPGHSGRYGVQGEKGSHGEVLGASPGSQGDPGLPGDQGEKGPIGNPGNPGYSGMGGMP GMIGFKGEKGSPGLIGEEGRPGPAGTHGFPGDPGRVGLPGPFGETGQPGITGDRGTQGDPGPPGPTGLKG TPGEHGDFGATGEPGLPGDPGQPGGSGRPGHPGLKGSKGSHGMSGFEGMMGNPGQKGLGGLKGEAGVSGE VGLKGLLGKQGAKGERGLTGPRGAIAVQMLVNVKGAKGDHGHQGMPGFTGPRGSKGVYGVPGFPGSDGLP GEPSKEKGQRGDPGAQGLPGFKGMPGITGNRGITGFEGMSGNKGIKGSPGAYGALGEDGRKGAKGDKGLR IDLPGNPGLRGEDGFAGEPGLKGLSGPTGDMGPTGFDGIEGIKGTVGDPGLAGIPGSDGQKGTPGNQGQK GFPGIPGKEGQPGFPGFSGIKGYPGLKGLYGLHGLKGHKGDQGTPGLEGFGRPGEPGHKGQKGEGGVHND QPGFPGAVGSKGYQGPQGDIGHPGQPGLPGLAGPDGTPDIPGQRGDPGFSGPTGHQGVPGSRGLPGLDAL PGERGVQGEPGAPGFPGTKGFRGDPGQSGYKGPHGVSGRKGVKGDQGVMGVPGQIGTKGDRGPSGPKGNT GIPGFPGPTGNRGPAPLPVITPGERGPPGVQGIMGPKGNRGEPGPQGPPGDSGFMGPIGERGMPGISGTP GVPGFRGEPGHMGHFGLQGKEGYRGNPGIPGFPGMPGRSVSVGYLLVKHSQSDQTPMCPVGMSKLWDGYS LLYFEGQEKAHNQDLGLAGSCLPRFSTMPFLYCNPGDLCYYASRNDKSFWLSTTASLPMMPVEESEIKPY ISRCSVCEAPSVAIAVHSQDITIPQCPAGWRSLWIGYSFLMHTAAGNEGGGQSLSSPGSCLEDFRTAPFI ECNGAKGTCHYFANKYSFWLTTTEQEFHSQPASQTLKAGQLLSHISRCQVCMKNL >XP_020769119.1 collagen alpha-2(IV) chain [Odocoileus virginianus texanus] MDRELRAAARPALRRWLLLGAVTVGLLAQSVLAGVKKLDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQG YTGPPGLQGFPGLQGRKGDKGERGAPGTTGPKGDVGPRGVSGYPGANGIPGHPGQGGPRGPPGYDGCNGT MGDAGSAGPQGPGGFLGPPGPQGPKGQKGEPYALPRQERDKYRGAPGEPGLVGMQGPPGRPGPIGQMGPV GAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGEMGLQGPGGIPPDNGYVEKPTPLYELLPEQYKGEKGS GGEPGRIGISLKGEEGIMGFSGSRGAPGFDGEKGSPGQKGSRGLDGYQGSDGLPGPKGETGDPGPPGLPA YSPHPSVAKGVRGEPGSPGQPGEPGARGEPGDPGLPGRPGTSIGDEDEKRGLPGEMGPKGFTGERGFSAV YPGPPGADGKPGLRGPPGRPGPPGPDGFLFGLKGARGGGGFPGSAGFPGARGQKGWKGDAGDCKCADQFI RGPPGLPGPKGFAGINGQPGSKGSQGDPGQHGLPGFPGFKGAPGNVGPPGPKGMKGDSRTITTKGERGQP GVPGVPGLKGGDGIPGPPGLDGFHGLPGPPGDGIKGPPGDAGQPGAPGTKGLPGERGPAGLGLPGPKGER GFPGDAGLPGPPGFRGPPGLPGAPGQIDCDSGVKRPIGADGQETIQPGCVGGPKGSPGQPGLPGPPGAKG LRGVPGFSGADGAPGLKGLPGDPGREGFPGPPGFMGPRGSKGAMGPPGLDGLPGTSGLPGPVGPPGDRGL PGEVLGAQPGPRGDSGLPGRPGLRGPPGERGPPGFRGSQGMPGMPGPKGQPGPLGLSGQPGLPGPPGLHG FPGAPGREGPLGPPGAPGFEGLPGDRGEPGDTGVPGPVGMKGESGDRGDPGQQGARGHPGSPGFKGVSGM PGAPGLKGARGSPGMDGFEGMLGLKGRPGIPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPII QPGMKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGIPGLPGRPGHVKGVKGDTGIPGVPGSPGFPG VPGSPGIMGFQGFTGSRGDKGAPGRAGLFGEVGPTGDFGDIGDTIDLPGSPGLKGERGTTGAPGLKGFFG EKGAEGDIGFPGITGLAGVQGPPGFKGQTGFPGLTGLQGPQGDPGRAGAPGTKGDSGWPGNPGLPGLPGL RGIGGLHGLPGSKGFPGSPGADIHGDLGSPGPAGDRGDPGEANTLPGPTGAPGQKGERGVPGERGPIGSP GLQGFPGITPPSNISGSPGDVGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGTKGWVGDPG PQGRPGVFGLPGEKGPRGEPGFMGNIGPTGSVGDRGPKGPKGDRGLPGDPGPVGAPGIAGIPQRIAVERG PVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGMSANPGFRGDQGPVGLQGPVGFEGEPGR PGSPGLPGMPGRSISIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFS TMPFLYCNPGDICYYASRNDKSYWLSTTAPLPMMPVAEEDIRPYISRCSVCEAPAVAIAVHSQDVSIPHC PAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYTNKYSFWLTTIPEQ TFQGTPSADTLKAGLIRTHISRCQVCMKNL >XP_030285421.1 collagen alpha-2(IV) chain isoform X1 [Sparus aurata] MSGTMRGQHDTGLSSLRLLLLLCVSIAILASGVHGGGKKHSGPCGGRDCSGGCQCFPEKGARGQPGPLGP QGHQGPQGRAGDPGIEGPKGQKGDHGRGGIVGPKGNVGMTGVPGFSGNDGIPGHPGQAGPRGKPGADGCN GTQGDSGFPGQTGYNGSPGSPGQPGRKGAKGDSLELSVYMERFRGDPGTPGVNGIFGPPGHPGWQGNRGI PGPKGPTGPPGPRGPKGTMTKVLKGLKGEQGDIGPPGPQGNSTHQHTLPPYGPSGPRGEKGLKGEIGDRA DNKGETGIMGFPGHRGESGLDGSPGLRGDPGYPGPKGRDGIKGVRGDAGLLISSGPSWPWSSTAGPPGPP GEQGPVGERGPVGDQGTPGPPGRPASDNYQVWQLFGPFGFKGEAGEKGQQGEPGRPAVSAGPPGTSGRPG GRGPQGPKGTWAEYFKGAPGGRGRPGNAGYKGVKGDHGECECSVVNSPAGQPGPAGEPGDAGMIGEFGQE GDVGDPGPRGEDGFPGHAGLSGVPGPKGQKGAETSATQKGYSGDPGVPGPNGGLGVPGAPGRDGLPGFPG SRGLPGEAPSRLRGDKGFPGLPGRPGVAGEAGEPGEGLKGIKGQRGLPGDDGITGYEGVPGTPGSPGGCS PRGDGEQVDVTGPCDPIPGPPGLPGAPGPTGLPGFPGSRGEKGVQGPLGVTGEKGESGEQGIGGRPGPPG FAGPRGDLGNPGRKGSLGVPGFPGVSGRHGSQGEKGVHGEILGASSGSPGDPGPPGFRGNKGQSGEPGEP GYPGMPGMPGMIGFKGEKGPAGLQGEEGRPGPAGRYGYPGDPGRAGPPGPPGATGQPGLTGERGTEGDPG PPGPIGLKGVPGTYGADGATGEYGLSGDPGLPGADGRPGLPGMKGYKGSTGMEGFEGMRGDVGVKGFSGS RGEPGVFGEVGPKGVTGHQGLKGDRGLRGPPGDKPHIPAQIIVDMKGAKGDHGNEGTKGFIGPRGSKGLP GVPGSEGYHGLPGDPNNEKGVQGDPGPQGLPGLKGMPGLTGNKGISGFGGMPGKTGIKGSPGAYGASGEK GRKGIKGERGPRIDLPGVPGLRGELGFSGDPGQKGLFGNPGDRGTLGFDGIEGRKGVSGEPGIPGNTGTD GQKGSPGSQGPKGFPGEPGKQGLPGFPGFRGEKGFPGLKGLYGLDGLKGQKGFQGKPGLDITGPAGESGA KGEKGEGGDPNNQPGDPGTAGLKGFQGSPGDHGQTGPPGLRGPRGPDGKPDKPGSRGDPGFVGAKGYEGF PGARGYPGVDAPPGEKGITGGSGFPGFPGIKGDKGDQGAPGYKGQHGVSGKKGVKGEQGFMGFPGVTGAK GERGPAGPKGSTGPPGFRGFPGNQGPLPIPIKVPGERGPPGPRGIQGPQGVRGGIGPHGPPGDGGFMGPV GQKGMPGISGRPGVPGFRGGVGPMGHPGLQGREGLRGNTGVPGLPGMPGRSVSVGYLLVKHSQTEQTPMC PVGMSKLWDGYSLLYLEGQEKAHNQDLGLAGSCLPRFSTMPFLYCNPGDLCYYASRNDKSYWLSTTAPLP MMPVEEGEIKPYISRCSVCEAPSVAIAIHSQDITIPQCPVGWRSLWIGYSFLMHTAAGNEGGGQSLSSPG SCLEDFRTTPFIECNGAKGTCHYFANKHSFWLTSIDQSFHTEPSSETLKAGQLLSRISRCQVCMKNL >XP_040192142.1 collagen alpha-2(IV) chain [Rana temporaria] METSENRKRCLRFHPSWKQNVLPWVLLLIALVMGFPGSVDAGGKSYTGPCGGRDCSQGCQCFPEKGSRGQ PGQLGGQGPQGPQGIIGIAGLQGRKGDKGERGHPGISGPTGDKGQSGVTGFSGANGVPGHVGQGGSRGKP GHDGCNGTKGDAGEAGFQGIRGPLGPLGNPGIKGHKGDPFYISEDMKKRIRGEPGEPGLAGYPGPNGPPG KVGFIGPMGELGLPGPAGPPGSAGPPGSKGIGFFGQKGEMGDPGKPGPPGVPCQTQGEPGTTGPTGAPCH LEQVKPSDTSIIDYLAEKGEKGERGDYGAPGEGVSSGELGEEGIMGFPGTRGPSGNDGAPGEKGENGLPG LNGNPGIPGFKGLKGEEGERGVPGPPTYATNLKTQKGEQGDPGFPGNVGLDGETGEKGSPGLPGLMGLPS PFPGPPGFPGLTGEKGQKGYQGNSGLPAFQKGRDGEPGEPGPRGPSGFPGYPGGRIGRKGAKGSPGNDGS DGYPGYAGLKGLKGEQGDCKCSAGDEATKGPAGDPGPVGFAGLTGEIGSKGEKGDRGGPGLPGAPGIKGP AGFNGLPGPVGEKGDGVIATEKGAKGERGTPGTQGAEGFEGFSGKDGLYGIPGSSGPPGDAPKGLLGEPG FAGSPGLEGARGEPGLPGVGFPGPKGAHGAPGQPGRNGSPGIPGLQGLPGDCFKEPGEDNQVGQRPVFPG RGCTLTPPPAPAGTRGPPGLPGFNGVRGVKGHIGQSGADGMHGFKGVRGDTGPDSLPGPQGFPGRRGDRG KPGTSGLPGERGPSGNPGAQGYQGTKGIPGDVLGAPSGSRGDVGWPGFSGLKGVQGDAGFPGFQGINGRP GTPGLKGISGDPGIPGTPGLPGPSGNGGFPGMQGKPGKPGTVGHSGLPGSPGSRGDEGEQGNPGQAWKKG EAGDEGELGIAGIRGRIGDPGFPGLTGMGGHPGVKGVRGSSGMGGFEGMKGEKGRSAFDGPKGQYGNFGL PGERGNPGVSGNKGDRGEEGPPGPEPKMEESMLEKMKGEKGILGVPGSPGVPGLNGTKGMPGHPGNPGLS GSPGMPSFDTGNKGDAGQSGFLGFPGSQGPVGPPGIRGFPGFTGPRGSKGMPGLYGIPGYKGEFGDKGQT GDSMDLPGERGNKGVIGDHGFPGQRGIHGEKGFSGDAGFPGIEGMSGDPGQPGQKGQTGLPGLLGISGPQ GDPGFPGVHGEKGNSGFSGLPGQQGFPGFRGRSGLDGLKGTKGLQGPAGVDVFGVSGIKGTPGQKGDQGE QNTLAGLPGNTGGIGARGEPGVPGVTGLPGLIGVRGLPGASNLSGIPGDIGPAGPPGQPGHPGPQGRPGV SSRPGEKGDPGPFGIQGIVGERGTPGDRGFQGFTGIPGYLGLKGQKGQQGIIGDFGLPGFSGDTGPKGPK GDRGSTGLQGAPGEPGLPPVPVRMKVDSGPVGVFGIVGPQGIPGDMGPRGPEGAKGVHGPQGKEGVPGIP GRSAAPGARGDLGSMGQRGPEGGRGTSGVPGSAGHPGMPGRSVNIGYLLVKHSQTEQEPMCPVGMAKLWS GYSLLYFEGQEKAHNQDLGLAGSCLQRFNTMPFLYCNPGDVCYYASRNDKSYWLSTTASLPMMPVVEDEI KPYISRCTVCEAPAVAIAFHSQDSSIPFCPDGWRSLWIGYSFLMHTAAGDEGGGQSLSSPGSCLEDFRAT PFIECNGARGTCHYFANKYSFWLTTIDNNFHSSPASDTLKAGLIRTRISRCQVCMKYL >CAE1304334.1 COL4A [Sepia pharaonis] MSEFPSLQRETTIAEKMTERMKSRHRRAEKTLKYCRQMQSKNFQVLTWLILIFLYITNSVANAQNSECGQICASGNCRCI GEKGSRGPHGPIGPRGVQGVRGYPGPEGLTGPKGDKGRAGPPGPSGPKGDRGKIGIPGYPGVPGIPGIPGEPGPRGPAGL DGCNGTQGSSGLPGIPGSPGKTGPPGFPGNPGRKGDSGLGLKGLKGEPGRPGIGLNGPQGPPGKHGISGPVGPIGPKGSK GSKGNQGMKGHKGISFRGDPGPRGPRGPPGKPVVPLDFSKSLEKTELKGEKGEIGDRGYEGLPGEKGDQGPPGMDGQLGM KGEKGVAGIAGPRGKQGIPGVPGPRGIKGDRGMEGLPGISGLPGLKGEPGRDGPRGFDGSVGPPGPPGGTVVGPPGDPGI QGPRGFTGPAGMKGNPGPVGPRGLKGEIGGPGIPGPPGNQGRDGPKGERGEQGFEGLPGKDGLLGRPGFPGAKGEPGQKG EPGIGDPGLDGIPGRPGKDGRPGAKGDTGLKGQTGPPGQTLDGNPGPTGPKGDKGGRGFKGQDGINGLNGLPGPKGDKGG ECNFCRQGSKGERGDPGLDGPPGRSGLSGSSGEKGEPGEPGEDGLYGPPGERGYPGDSGLPGSSGPKGQKGEPVQAPVIK GEKGNAGLPGIAGLSGNKGASGPPGPTGPPGLSGPKGEMGFAGLPGADGRPGEAGRPGRPGAKGVPGYGLSGPKGQPGEP GQPGVSTLGPKGDKGDPGRKGEPGDRGFPGAKGLPGLPGPKGFDGLPGRPGLDGMKGERGQNGLPGTAGPRGYNGPRGAK GEPGLAGLPGEAGITGAKGDRGFSGLKGSKGQSSNASVPGSPGRKGERGLDGLPGQRGLDGTPGQRGDRGPTGEDGLPGL PGRDGAKGEPGIGLPGRPGPQGPPGLNGIPGSSGLKGEPGSSGLPGLPGKPGLKGKDGLPGQPGLPGLDGEPGIMGPVGK PGLPGLPGSKGERGAVGFSGEPGRNGAPGLPGVKGERGDDGLIGLPGRNGLDGLPGMKGASGLPGLSGMKGEPGRVASKG EKGEPGLSGLPGERGLDGTPGRDGLPGIQGEKGEPGIGQSGLPGEDGPPGLSGLPGQRGPVGPKGDAGPSGFPGMKGEPG YPGKPGLSGIPGNDGLPGQKGDRGFPGQDGLPGLKGEPSTNGLPGLPGEKGESGPRGPPGQRGYAGMKGDRGLDGFPGAK GNSGLPGTSGIPGADGLPGLPGEKGNSGLPGFPGSDGEIGDKGDRGFPGEKGDEGPLNLAKIKGERGFTGNTGPKGDKGE QGPNGLNGIEGQKGEKGSRSRSEIPGLKGEPGYPGAKGEPGLPGAPGLDGLPGRDGVKGADGRPGPPGNDGLPGEKGLPG LSGEPGLQGQPGLDGLKGEPGLPGLPGLSGEKGDSGLSGLPGENGRSGLKGERGDTGRPGEPGPAVMGPKGNKGLPGLTG PPGFPGLKGDTGLPGNPGLPGLAGERGLPGEAGLTGLPGADGRPGLQGKPGLPGTPGLMGPPGPRGPAGRSAAVGFLFAR HSQTTEVPVCPDGLTKLWDGYSLLYLEGNERSHHQDLGWAGSCIKRFSTMPFLFCDFNDVCNYASRNDKSYWLSTNAPMP MMPVGQNEIPPYISRCAVCDSSTNVIAVHSQTLNLPDCPQGWEGLWIGYSFAMHTGAGAGGGGQSLSSPGSCLEDFRATP FIECSGHAGTCHYFANKYSFWLTTIEQSQQFRAPQPQTLKAGSLRTRVSRCQVCMKKIGGRRHHNRGFTGPA >ACK77661.1 RE33133p [Drosophila melanogaster] MLPFWKRLLYAAVIAGALVGADAQFWKTAGTAGSIQDSVKHYNRNEPKFPIDDSYDIVDSAGVARGDLPPKNCTAGYAGC VPKCIAEKGNRGLPGPLGPTGLKGEMGFPGMEGPSGDKGQKGDPGPYGQRGDKGERGSPGLHGQAGVPGVQGPAGNPGAP GINGKDGCDGQDGIPGLEGLSGMPGPRGYAGQLGSKGEKGEPAKENGDYAKGEKGEPGWRGTAGLAGPQGFPGEKGERGD SGPYGAKGPRGEHGLKGEKGASCYGPMKPGAPGIKGEKGEPASSFPIKPTHTVMGPRGDMGQKGEPGLVGRKGEPGPEGD TGLDGQKGEKGLPGGPGDRGRQGNFGPPGSTGQKGDRGEPGLNGLPGNPGQKGEPGRAGATGKPGLLGPPGPPGGGRGTP GPPGPKGPRGYVGAPGPQGLNGVDGLPGPQGYNGQKGGAGLPGRPGNEGPPGKKGEKGTAGLNGPKGSIGPIGHPGPPGP EGQKGDAGLPGYGIQGSKGDAGIPGYPGLKGSKGERGFKGNAGAPGDSKLGRPGTPGAAGAPGQKGDAGRPGTPGQKGDM GIKGDVGGKCSSCRAGPKGDKGTSGLPGIPGKDGARGPPGERGYPGERGHDGINGQTGPPGEKGEDGRTGLPGATGEPGK PALCDLSLIEPLKGDKGYPGAPGAKGVQGFKGAEGLPGIPGPKGEFGFKGEKGLSGAPGNDGTPGRAGRDGYPGIPGQSI KGEPGFHGRDGAKGDKGSFGRSGEKGEPGSCALDEIKMPAKGNKGEPGQTGMPGPQGEDGSPGERGYTGLKGNTGPQGPP GVEGPRGLNGPRGEKGNQGAVGVPGNPGKDGLRGIPGRNGQPGPRGEPGISRPGPMGPPGLNGLQGEKGDRGPTGPIGFP GADGSVGYPGDRGDAGLPGVSGRPGIVGEKGDVGPIGPAGVAGPPGVPGIDGVRGRDGAKGEPGSPGLVGMPGNKGDRGA PGNDGPKGFAGVTGAPGKRGPAGIPGVSGAKGDKGATGLTGNDGPVGGRGPPGAPGLMGIKGDQGLAGAPGQQGLDGMPG EKGNQGFPGLDGPPGLPGDASEKGQKGEPGPSGLRGDTGPAGTPGWPGEKGLPGLAVHGRAGPPGEKGDQGRSGIDGRDG INGEKGEQGLQGVWGQPDEKGSVGAPGIPGAPGMDGLPGAAGAPGAVGYPGDRGDKGEPGLSGLPGLKGETGPVGLQGFT GAPGPKGERGIRGQPGLPATVPDIRGDKGSQGERGYTGEKGEQGERGLTGPAGVAGAKGDRGLQGPPGASGLNGIPGAKG DIGPRGEIGYPGVTIKGEKGLPGRPGRNGRQGLIGAPGLIGERGLPGLAGEPGLVGLPGPIGPAGSKGERGIAGSPGQPG QDGFPGAPGLKGDTGPQGFKGERGLNGFEGQKGDKGDRGLQGPSGLPGLVGQKGDTGYPGLNGNDGPVGAPGERGFTGPK GRDGRDGTPGLPGQKGEPGMLPPPGPKGEPGQPGRNGPKGEPGRPGERGLIGIQGERGEKGERGLIGETGNVGRPGPKGD RGEPGERGYEGAIGLIGQKGEPGAPAPAALDYLTGILITRHSQSETVPACSAGHTELWTGYSLLYVDGNDYAHNQDLGSP GSCVPRFSTLPVLSCGQNNVCNYASRNDKTFWLTTNAAIPMMPVENIEIRQYISRCVVCEAPANVIAVHSQTIEVPDCPN GWEGLWIGYSFLMHTAVGNGGGGQALQSPGSCLEDFRATPFIECNGAKGTCHFYETMTSFWMYNLESSQPFERPQQQTIK AGERQSHVSRCQVCMKNSS >XP_038051105.1 collagen alpha-2(IV) chain-like isoform X1 [Patiria miniata] MRLDVFAALGRTLGGQNSAPRTLTSTMWRWGVVAVLLLAFVGSSIAQKADCGATCKACNCKGRQGQRGTPGQIGPEGDRG ARGILGYQGVQGPKGDIGDPGAAGPRGQKGDRGMTGVPGFPGLNGYTGLPGPKGPYGNPGVAGCNGPKGEDGIPGIGGYG PRGPPGFNGPKGSKGEPAPYTPAIQGRRGDPGFDGPDGNPGQQGRNGYPGQQGDRGFKGFQGSRGFDGYQGPPGANSPGY KGPKGEPGAQGPKGRSASPFSNPPNIKGSPGTKGDRGETGAKGDVGMFGMQGPKGDPGPKGGKGFLGMKGEKGVLGIAGP RGPVGYTGLPGAPGFIGDRGFDGTRGQDGVPGYQGFRGDVGDDGPIGFKGDAGIPGEIGDGPVGPPGPDGDPGLQGHPGA RGAVGDPGEEGLPGRLGEIGGPGPVGRPGLSRDGQQGDRGVGGIPGKQGFQGSPGEQGQKGQPGDKGAPGFPRAGPVGMD GAFGRVGERGRKGVVGAQGRPGPPGLTPLGEEIVGPIGETGPRGPKGVVGASGPQGPSGGKGFPGRPAGPCPRCPQGLKG QPGDIGFPGTDGRFGPDGERGPTGEKGANGEPGYLGRQGQPGFPGLRGPRGLKGDTGDRGTPGRSIPVRGYKGERGEQGL KGQIGEPGTQGIQSPFDLNQFRNMTQKGEMGEKGRKGGRGTDGAPGPAGEDGVDGERLDGPRGPKGVMGEDGRFGFLGPK GQKGEPAERVDIEEPIPGPRGEPGPQGAKGGRGPAGFQGQIGFPGPFGDMGIRGTKGGSGFPGVPSFPGPKGFPGPRGDK GLVGIQGEIGRQGRQGEPGNPGFPGRDGMRGDRGEDGQSGSVGPTGFPGDEGPQGIKGTNGFNGLPGQSGFPGFQGMNGE RGDPGPFGPQGERGLKGATGIGFPGRQGSPGRDGPRGPQGPTGAEGPPGDRGVFGGIGSTGDNGEDGFPGERGQQGERGE KGFPGRAGRPGLFGARGEFGDPGLDGLPGNPGQKGNAGFPGFSGRPGEPGPQGLPGKDGLPGLIGETGDPGRTGQVGLFG DFGEPGDIGEPGEDGADGLIGPLGQDGRPGSPGFPGPIGNRGFSGITGMVGDKGGVGEQGRPGNLGLDGLTGEKGYRGLR GFRGVTGFEGDLGLIGRPGPRGPQGPAGQKGDSGVPGTPGLFGEVGPPGDPGSRGSKGIKGSSFNPNDIKEPGTGEKGAK GEKGDQGSRGLNGLRGTVGDRGPSGEPGNQGYDGYDGFDGIAGMRGDPGLPGLFGVEGLPGMPGEDGNPGIKGRQGLPGP QGPKGVIGFSGFSGFPGSAGTDGRPGERGPRGNKGFPGLPGVPGFPVFIAPAGEPGEDGPRGPDGPKGFVGQPGQPGFPG FSGLKGPKGEPGLTGLGSPPVLGPPGAKGIQGPTGVPGLKGRVGDIGFPGPVGELGPFGLKGYPGYPGRQGRPGLPGFNG PKGQPGDQPDAQKGVKGDSGDPGPFGIRGRPGRPGFAGVDGSVGLKGMKGDFGDPGEPGSIGPKGQFGPQGLRGDFGDPG PQGFKGGKGVGGEEGSPGPPPRPQGFIVVKHSQSRNIPRCDVGMTQLWTGYSLLYTEGNEKAQHQDLGLAGSCLPRFSTM PYVFCNFNEICNFAQRNDKSYWLATSEAIPMMPVEGNGIRPYISRCAVCETPTQVIAVHSQDTTLPDCPRNWRSLWIGFS FAMYTSAGADGGGSALASPGSCLEDFRATPFIECNGRGRCFFYRNTYSFWLTTVDADAMFRPQESQTLKAGSLRSRVSRC QVCQKIL >NP_001022662.2 Collagen alpha-1(IV) chain [Caenorhabditis elegans] MSRLSLLGLTAAVVLLSSFCQDRIHVDAAAACKGCAPPCVCPGTKGERGNPGFGGEPGHPGAPGQDGPEGAPGAPGMFGA EGDFGDMGSKGARGDRGLPGSPGHPGLQGLDGLPGLKGEEGIPGCNGTDGFPGMPGLAGPPGQSGQNGNPGRPGLSGPPG EGGVNSQGRKGVKGESGRSGVPGLPGNSGYPGLKGAKGDPGPYGLPGFPGVSGLKGRMGVRTSGVKGEKGLPGPPGPPGQ PGSYPWASKPIEMEVLQGPVGPAGVKGEKGRDGPVGPPGMLGLDGPPGYPGLKGQKGDLGDAGQRGKRGKDGVPGNYGEK GSQGEQGLGGTPGYPGTKGGAGEPGYPGRPGFEGDCGPEGPLGEGTGEAGPHGAQGFDGVQGGKGLPGHDGLPGPVGPRG PVGAPGAPGQPGIDGMPGYTEKGDRGEDGYPGFAGEPGLPGEPGDCGYPGEDGLPGYDIQGPPGLDGQSGRDGFPGIPGD IGDPGYSGEKGFPGTGVNKVGPPGMTGLPGEPGMPGRIGVDGYPGPPGNNGERGEDCGYCPDGVPGNAGDPGFPGMNGYP GPPGPNGDHGDCGMPGAPGKPGSAGSDGLSGSPGLPGIPGYPGMKGEAGEIVGPMENPAGIPGLKGDHGLPGLPGRPGSD GLPGYPGGPGQNGFPGLQGEPGLAGIDGKRGRQGSLGIPGLQGPPGDSFPGQPGTPGYKGERGADGLPGLPGAQGPRGIP APLRIVNQVAGQPGVDGMPGLPGDRGADGLPGLPGPVGPDGYPGTPGERGMDGLPGFPGLHGEPGMRGQQGEVGFNGIDG DCGEPGLDGYPGAPGAPGAPGETGFGFPGQVGYPGPNGDAGAAGLPGPDGYPGRDGLPGTPGYPGEAGMNGQDGAPGQPG SRGESGLVGIDGKKGRDGTPGTRGQDGGPGYSGEAGAPGQNGMDGYPGAPGDQGYPGSPGQDGYPGPSGIPGEDGLVGFP GLRGEHGDNGLPGLEGECGEEGSRGLDGVPGYPGEHGTDGLPGLPGADGQPGFVGEAGEPGTPGYRGQPGEPGNLAYPGQ PGDVGYPGPDGPPGLPGQDGLPGLNGERGDNGDSYPGNPGLSGQPGDAGYDGLDGVPGPPGYPGITGMPGLKGESGLPGL PGRQGNDGIPGQPGLEGECGEDGFPGSPGQPGYPGQQGREGEKGYPGIPGENGLPGLRGQDGQPGLKGENGLDGQPGYPG SAGQLGTPGDVGYPGAPGENGDNGNQGRDGQPGLRGESGQPGQPGLPGRDGQPGPVGPPGDDGYPGAPGQDIYGPPGQAG QDGYPGLDGLPGAPGLNGEPGSPGQYGMPGLPGGPGESGLPGYPGERGLPGLDGKRGHDGLPGAPGVPGVEGVPGLEGDC GEDGYPGAPGAPGSNGYPGERGLPGVPGQQGRSGDNGYPGAPGQPGIKGPRGDDGFPGRDGLDGLPGRPGREGLPGPMAM AVRNPPGQPGENGYPGEKGYPGLPGDNGLSGPPGKAGYPGAPGTDGYPGPPGLSGMPGHGGDQGFQGAAGRTGNPGLPGT PGYPGSPGGWAPSRGFTFAKHSQTTAVPQCPPGASQLWEGYSLLYVQGNGRASGQDLGQPGSCLSKFNTMPFMFCNMNSV CHVSSRNDYSFWLSTDEPMTPMMNPVTGTAIRPYISRCAVCEVPTQIIAVHSQDTSVPQCPQGWSGMWTGYSFVMHTAAG AEGTGQSLQSPGSCLEEFRAVPFIECHGRGTCNYYATNHGFWLSIVDQDKQFRKPMSQTLKAGGLKDRVSRCQVCLKNR >XP_039251035.1 collagen alpha-2(IV) chain-like [Styela clava] MRKSILFIVIIGIICIQEATARKRKRNIKGPCAGRDCRNLGPCSFCVSEKGNRGFPGRQGDVGTTGPPGFPGPEGLSGPK GEKGYPGRIGARGQSGSRGETGAPGYAGVNGLPGHPGEQGPVGHPGLDGCNGTEGDLGPRGEAGPPGLPGPVGRDGAPGE KGEPAYVDDASMIKGASGEDGPIGPEGRPGIQGPVGQMGPMGYDGPPGPPGPPGRKGQKGDEGNEGIGYQGEKGEKGSIG TAGGRPDFLERNPPGFTQPLKGLPGRNGSKGYKGEKGDIGFPGFVGPPGFDGMQGETGEKGVRGPAGPRGPSGVPGVNGF NGRKGEPGDDGRPGTDGAQGLKGERGVPGSEGIPGFRGLDGLDGPSGPPGFPGPEGERGIRGETGIPGLDGQSGLHGEKG ERGNRGPAGSPGDSVQGEKGRTGLKGLDGLDGVPGPAGLPGDKGSRGDVGAPGRSVKGESGKDGMDGLPGLRGLQGPRGR PGESGKLIYDGENIVGETGPTGDVGAKGAKGLKGEMGPTGLMGMKGDHGGECDCADAVGERGDPGSRGPPGYPGRNGLPG IPGREGERGPPGENGAMGTPGDLGPRGFSGIPGPPGRKGEPATGDIFKAQKGEQGVPGGQGPPGLDGLPGRAGGIGGPGA RGEKGELGPIGKPGKPGPQGSDGERGNPGRPGRDVEGTPGARGLKGESGRPGLPGITGYPGKQGPPGEALEVEVPRGEKG LMGLPGPPGLPGSKGDTGDMGRPGVDGLAGVVGESGEPGPPGLPGLPGPKGFPGETGDKGGPGPPGRDGYDGDYGVPGPP GEKGVKGERGVSDIRGRTGGEGPKGNPGKGGGKGPVGEPGTPGEPGKMGADGKPGPDGEPGLIGPAGRLGPPGQKGESAF EGRPGDRGPTGPRGPPGLIGVTGPKGEIGGAGPPATGKFKGMKGFPGLPGKYGEKGFTGPPGQAGEPGRPGFEGFPGPNG MMGVIGSVGLPGPPGKMGQKGSYGPEGPKGDTGREGIPGDVGGRGDVGSKGPKGEKGQPGEALNVTIVGQLMASKHGEPG APGERGLPGLPGMIGMTGKKGEEGDPGKKGEPGEAGPSTGGLPGRPGLDGLNGEDGETGEPGLPGLIGESGEKGDVGRPG PNGLPGPSGETGQPGRDGPEGSPGLAGLDGLNGMNGDKGTKGRPGLSGIVGISGMPGTRGIRGDRGFTGPPGTPGEKGMV GFPGRNGIDGLNGRTGLSGPTGTKGEKGDAGISGLDGLDGTDGTNGPKGRPGFSDVPGPAGSIGLPGLQGPPGESGLPGL SGSQGRQGDRGDVGLPGLGGRQGFPGDAGLPGFPGEKGEAGLNGRQGLPGPPGPPGPEGEIGLPGNAGERGMRGMNGNPG LPGRDGRPGSPGESGSPGDIGERGDKGMKGMSGLTGIQGPDGAKGNAGLQGQIGRPGFPGRPGERGDAGPPGRSLEPENV PPGPKGEKGRRGLPGLMGLEGEPGPSGIEGFKGEPGIPGRNGINGIPGPRGERGSDGPTGLTGPQGPAGLDGARGTKGRT GKPGKFRPAGHLIVRHSQTVDVPTCPGGTSKLWSGFSMLYLSGSERAHGQDLGSTGSCLRRFNTMPFLYCNVNEVCNYAS RNDKSYWLATTLPIPMMPVETGLEEYVSRCTVCESQSIAMAFHSQSDMIPDCPNGWKGLWFGYSFVMHTASGADGSGQSL SSPGSCLEDFRATPFIECNGARGHCFFYNNQFSYWLTTISKEEQFTSPKKETLKAGNLRTRVSRCQVCAKVL >XP_006563187.2 collagen alpha-5(IV) chain [Apis mellifera] MVPRANATRGLRSFPVVLRVTCVLALLVVTWIPVTEAVICRDSYKCNCTGIKGGAGYPGIPGLQGPEGPPGDIGPDGPPG PKGEKGAGGEYGGMGEKGYRGEQGIQGFPGAAGLPGKPGSPGVMGPDGLDGCNGTDGRAGSPGIPGVHGERGPPGPMGDY GPIGEPGDGGINSVGVKGVRGNPGMNGLEGYPGSYGIPGEMGYPGETGDMGFRGSPGLPGMQGDVGDTVYGIKGAEGEQG DRGEPGPPSNGEFKEKTKVTPVKGATGPKGMRGDAGERGRKGEMGAKGPIGRAGFFGIKGTKGEQGDDGPRGKQGAEGPP GPAGEKGEKGAPGYAGKPGPDGFDGELGDGGNQGPPGKQGAPGEPGKYIPELDEIIQGNIGIQGDLGPPGNPGEPGTPGL PGKVGYIGPPGPPGPPGSSGLPGLKGSSVKGEPGDDGFTGEMGLQGPPGAPGIPGTVGLKGYPGLTIVGPPGPDGKPGYP GVPGLPGDRGDPGVQGPKGFPGKGSRNPGPPGERGLPGIPGLPGPDGWPGLPGLKGVKGFKGDDCNCPPVKPGPKGEQGD SGLDGYPGTPGYPGLPGPRGFKGVQGKRGIVGPRGLEGDSGRPGVAGPQGPKGERGRLIVPDKKIIGTPGDIGDKGYPGI EGPTGPRGEPGFRGDTGPEGPKGEKGELGPPGRPGGDGYPGINGIPGEKGDDASTPMEFLKGEPGSPGIPGLRGPPGDKG AKGERGISSQYNIQLKGEKGYKGERGDPGEDGAKGPEGWPGDEGFIGPSGIPGSPGISRQGPVGLKGYPGMPGDQGPRGA PGTPGSEGFVGFPGRVGNKGDRGDPGSNQTYGDYGLMGWTGEKGNVGDAGPMGYRGRPGPDGTKGAKGSKGAPGSAGIPG LQGVKGQRGDRVQGSKGMPGIHGQPGMPGRMGEVGIPGPDGTLGFDGMKGLKGEIGFMGRRGDDGDIGPPGYLGRDGIPG LPGPPGPDGDVGEIGEPGPRGWLGLEGLSGPMGAKGEQGDVGPVGIPGIVGLPGSKGISGDPGPVGLDGLPGENAFSGPQ GDIGEPGFMGEVGAPGLPGMDGRPGLPGEPGLATDGFNGLRGEKGEAGINGLNGLPGPKGEIGDMGLDGLKGARGDWGLK GRPGIPGSPGLHAVKGERGPIGPPGIEGLKGKRGLDGDPGRMGLPGMPGDQGHRGSPGLMGAPGPKGYVGEPGLPSYGEV EGGDFGMPGLNGLPGEKGERGEQGFVGLPGRKGMKGNIGYRGPDGFPGVPGFPGLPGDEGPPGFPGISGQFAEPGEDGRP GMDGIPGTPGIPGQKGAPGEYGPNGPIGITGDVGFSIRGPKGLAGDMGPRGFDGYPGAPGLQGMPSLPGLPGPKGYPGEI GLPGISIKGESGERGLDGFDGRPGTKGIRGDSGLSGFVGLPGAKGEPGDVGEPGIIGLPGPPGPKGPKGDRGMNPFSPFP RKGLPGDTGPPGLPGFPGLPGMLGEPGEDGLPGREGEPGMVGLPGLPGPEGEEGPAGYTGPPGVIGRQGLPGSPGISGNP APPAPGPRNRGFYFARHSQSEMIPLCPPNTIKLWDGFSLLHVRANGKSHGQDLGTAGSCVVKFNTMPFTFCNLNNQCNYA DREEFSYWLSTTEPMPMSMAPIPAPQVGRYISRCSVCEAPTRAIAVHSQTMAIPQCPGGWEELWIGYSFLMHRDVGNGGG GQSLVSPGSCLEEFRIRLFIECRSKGTCNYFSTATTFWLTTIKDYEMFRKPIPQTLKTDHTSRVSRCVVCLRRRVTEDVK SLKPFISNGQREQVGNIRYSPHSRPVHYPDYQYQKKPPIGRTRGPNRRVPYHYRKKGGRLRKPERTTEPPEAA >NP_999631.1 3 alpha procollagen precursor [Strongylocentrotus purpuratus] MKYREVLERHVFVCLSLLIIVFAYWADAAACVGCLSATCICNGTKGERGDRGYVGFPGPPGPGGFPGVEGPPGYKGQKGN LGIAGSGGPKGFRGSLGNPGIPGIPGIPGEPGQEGPPGEPGIPGCNGTKGERGPSGPTGFGQPGSPGPRGDPGPQGPPGD TTYGLKGIKGEPGRLGRDGYPGTPGDSGPTGPKGISGDPGLLGSKGTRGLKGEPGQPGVQYQGGKGEKGSVGTQGLPGES CRDQAATGNDTTIVQGRPGPKGDQGEYGDKGDKGFLGMKGMKGPKGQYGLKGEKGLSGPQGPRGKIGKDGTPGNQGMKGS PGIPGNPGPTGFNGQLGDKGDRGPKGRVGPPGPPGPSVPVNDKGTKGLPGPSGRHGSAGPRGYPGEKGRTGYDGKAGQPG PPGSAGDRGVPGPVGIGEKGEPGNPGIPGMPGPNGFQGLPGRDGPKGDKGMAGLTIQGLPGMDGRPGPDGPAGLPGQVGD AGPQGLIGEPGNGLPGDPGPKGQTGRDGPRGIPGDVGSSGQPGLPGPQGSKGEACAACRSGEIGPKGDPGQSGEIGQPGQ PVYNGNSGPSGPKGDRGLRGLTGRDGQDGPQGPPGSTGRPGNKGQLGLQGEVGFTEPGPRGIQGDPGLKGDNGLNGEPGP PCEPGAVKVNGEKGALGPPGPPGRDGVPGYQGQKGDRGLPGDSLRGSNGEKGDQGPRGERGTYGSPGDKGEVVYYETGTQ GPKGEPGNPGTAGPPGPAGPTGNQGLPGDQGPDGYQGEKGSQGQSGPPGNSIPGSPGEKGAQGIPGDVGQPGQPGPTGPL GNPGIPGAFGEKGDFGPQGNPGGQGLRGLTGQPGQPGIGGERGNIGDPGTRGRDGIPGQAGGKGETGPGGLPGGPGIKGE PGLSIPGQDGSSGTPGRDGAPGGPGEPGPSGPRGEPAQPLLEETRITRLNGQRRPPGQPGDNGAPGNDGEPGPAGQIGVK GSPGPLGPGGSQGPPGSPGPIGAPGEKGERGGMGTPGSPGPSGSPGAKGEPGLPGPLGEKESRGPGGVPGSKGESGIPGR SGGIGSPGSIGLPGLNGVKGEPGIPGNSGIPGGRGLNGEPGPAGFKGFQGLLGVKGDFGIKGQMGFPGPKGDNAQMGIPG QNGGEGFPGRSGIPGPQGAPGSPGEPGTDGSNGGPGSKGEKGQPGIIRDLLAGWRKGVKGDPGRTGPEGAKGNPGLPGIP GESGDAGLPGSEGRPGQPGTSGPPGPPGPNGEPGLIGRTGTPGDPGPRGERGSYGTPGEDGIPGVKGDSGDPGLMGLPGG PGLPGPGGPPGESGFPGVRGVKGIPGTPGLSALGIKGEPGFPGLKGDSGQPGLNGGSGSIGLPGMKGTKGETGPVGPRSP LPPVIPGPKGEIGIPGANGDRGDKGDRGEPGRPGFQGRPGESGSPGLNGQMGDPGGPGFQGLKGSKGEPGPIPNVFEMKG VKGDRGGPGPDGPQGPPGRDGRPGPQGPPGLTGDKGTPGVQGNPGVSGVPGEPGLKGEQGFRGQNGQPGDPGFPGTKGEA GIPGSSSGFFITRHSQTTSIPQCPQGTAKMWHGYSLLFVQGNERGHGQDLGKPGSCLKRFSTMPFLFCNINNVCHVASRN DYSYWLSTTEPMPMNMAPIRGGQLQPFISRCVVCEAPAQVLTVHSQTVNIPDCPDRWGVLWIGYSFMMHTGPGGEGSGQM LSSPGSCLEDFRSSPFIECHGDGKCNYYATTYTFWLSSITGNAQFTMPQSETLKAGSLRTRVSRCAVCLRNQ >XP_031568877.1 collagen alpha-2(IV) chain-like [Actinia tenebrosa] MEGIMGPRGIKGDKGEFGAEGAKGPRGKVGRPGFPGQPGIPGIPGNEGARGEHGEPGCNGTQGDRGSDGQPGRPGRIGVK GNIGPPGPRGFPGEAPSTLKGVKGEPGPFGPVGPQGPRGDVGVPGPKGDIGPPGPLGIPGPPGPTGKKGEMGIRFEASKG DKGAKGVPGPKGQPNPILPSTCGNTTATLKGEKGPPGLRGLPGPRGEKGEPGVNGPIGERGFPGQKGNKGEPGNDGPVGK PGKDGDIGLPGPMGXRGFPGDIGLPGEPGPVGPSGAPGAPGPQGKEGAPGPPGVGPPGFQGDTGATGTPGFPGIKGARGP PGPPGNIGPLGPPGPQGFKGDKGPLGPPGIIGTPGSPGMKGPPGKPGAQGDPGTPGDRGPRGFTIQGDPGMDGLPGPRGE TGGKGDRGFPGPPGSSTNGPPGEKGEPGFPGVQGNDGPSGPQGPKGDQCGPCPTPPAGPKGDKGSVGLPGENGAVGPPGE IGVPGAPGKPGTTGRSGRPGPMGPSGDPGIKGKDGAKGDRGELIKIKGEKGTPGTSGPPGPFGPPGIRGRPGADGQKGSP GPTGSIGLKGAPGVNGKDGLKGAPGFSGPKGEKGEKGLFVQGRPGXPGPQGERGPLGPKGLPGPTGEKGTSWDNTQGQIN QGXPGDPGVPGKDGLKGEKGDNGKGGLPGPPGARGVDGAKGVDGEGQPGPPGPPGPQGQRGPIGEKGDSGPPGSQGFTGP DGLPGPRGPTGLKGDDGPPGRPGLPGTPGLRGFDGIKGNPGPPGRDGLPGQPGERGSIGAIGLPGEPGPKGTAGVKGDKG DKGLSVEGPPGEPGPPGLRGSPGLKGVRGRDGSNGANGFPGGPGLNGDIGLPGDPGNSGPPGPPGLPGKDGTDGNIGEKG FPGLPGPRGPSGENGLPGTRGAQGTPGDPGIPGPPGDTGRAGFPGFKGDKGGKGIQGPPGTTEPGNIPGPKGMTGNPGQP GPPGANGVDGIRGFKGDIGLPGDIGTPGPPGKSGQPGPPGPPGSPGKKGENGRDGINGINGLRGDIGLPGPPGVDGTDGT PGSEGPPGQKGSKGNPGRGLVGPRGPPGAPGMKGLPGFPGIKGSKGVNGADGRPGDIGPVGPKGFKGSSGAKGDQGENTV ERGPPGPPGLPGRDGIDGLNGEKGNTGVPGNPGPPGAQGVRGRKGDKGVSGLPGQRGPSGDPGPRGPQGPRGIAGVPGNP GSPGIPGLPGMPGLKGAKGELGLPGTPGSDGTPGAKGDKGNPGFPGVDGRPGEDGPAGEKGDTGLPGTXGAKGATGRPGV EGPSGARGSPGLPGFKGLKGEPGKDGLPGTPGNKGAPGADGFPGLPGXKGNTGIPGLPGLKGEKGYGLGTXGPKGDRGDA GLPGINGDKGEPGIPGFPGGPGPKGDKGLMGADGREGPRGNPGFPGRDGSKGESGPAGLPGVPGPTGRRGPQGTSDFGFF FTRHSQTDQLPSCPDSTFPLWTGYSLLYVQGNERAHGQDLGSPGSCLRRFSTMPFLFCNIENVCNLASRNDYSFWLSTTA PVPMMPVREENVQRHISRCAVCEARAQVIAVHSQSNALPDCPRDWDPLWQGYSFLMHTSAGNDGSGQPLSSPGSCLEDFR AHPFIECHGRGTCQYYGSTYSFWLATVDAKNQFRVPRPETLKAGTLRERVSRCKVCMRRLPKPKGVATGGRLRN >XP_043748401.1 collagen alpha-2(IV) chain [Cervus elaphus] MDRELRAAARPALRRWLLLGAVTVGLLAQSVLAGVKKLDVPCGGRDCSGGCQCFPEKGGRGQPGPVGPQGYTGPPGLQGF PGLQGRKGDKGERGAPGTTGPKGDVGPRGVSGYPGANGIPGHPGQGGPRGPPGYDGCNGTMGDAGSAGPQGPGGFLGPPG PQGPKGQKGEPYALPREERDKYRGEIGEPGLVGMQGPPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLGFYGEKG EKGDMGLQGPGGIPPDNGYVEKPTPLYELLPEQYKGEKGSGGEPGRIGISLKGEEGIMGFSGSRGAPGFDGEKGSPGQKG SRGLDGYQGSDGLPGPKGETGDPGPPGLPAYSPYPSVAKGVRGEPGSPGQPGEPGARGEPGDPGLPGRPGTSIGDEDEKR GLPGEMGPKGYTGERGFPAVYPGPPGTEGKPGLRGPPGRPGPPGPDGFLFGLKGARGSGGFPGSAGFPGARGQKGWKGDA GDCKCADQFIRGPPGLPGPKGFAGTNGQPGSKGSQGDPGQHGLPGFPGFKGAPGNVGPPGPKGMKGDSRTITTKGERGQP GVPGVPGLKGGDGIPGPPGLDGFHGLPGPPGDGIKGPPGDAGQPGAPGTKGLPGERGPPGLGLPGPKGERGFPGDAGLPG PPGFRGPPGLPGAPGQIDCDSGVKRPIGADGQETIQPGCVGGPKGSPGQPGLPGPPGAKGLRGVPGFSGADGVPGLKGLP GDPGREGFPGPPGFMGPRGSKGAVGPPGLDGLPGTSGLPGPVGPPGDRGLPGEVLGAQPGPRGDSGLPGRPGLKGPPGER GAPGFRGSQGMPGMPGQKGQPGSPGLSGQPGLPGPPGLHGFPGAPGREGPLGPLGAPGFEGLPGDRGEPGDTGVPGPVGM KGESGDRGDPGQQGARGHPGSPGFKGVSGMPGAPGLKGARGSPGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAG EPGVKGSRGDPGPPGPPPIILPGMKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGIPGLPGRPGHVKGVKGDIGIP GVPGSPGFPGVPGSPGIMGFQGFTGSRGDKGAPGTAGLFGEVGPTGDFGDIGDTIDLPGSPGLKGERGTTGAPGLKGFFG QKGAEGDVGFPGITGLAGVQGPPGFKGQTGFPGLTGLQGPQGDPGRAGAPGTKGDSGWPGNPGLPGLPGLRGIGGLHGLP GSKGFPGSPGADLHGDLGFPGPAGDRGDPGEANTLPGPTGAPGQKGERGVPGGRGPMGSPGLQGFPGITPPSNISGSPGD IGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGTKGWVGDPGPQGRPGVFGLPGEKGPRGEPGFMGNIGPTG SVGDRGPKGPKGDRGLPGAPGPVGAPGIAGIPQRIVVERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGR GGMSANPGFRGDQGPMGLQGPVGFEGEPGRPGSPGLPGMPGRSISIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEG QEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYASRNDKSYWLSTTAPLPMMPVAEEDIRPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYTNKYSFWLTTIPEQ TFQGTPSADTLKAGLIRTHISRCQVCMKNL >XP_043334259.1 collagen alpha-2(IV) chain [Cervus canadensis] MDRELRAAARPALRRWLLLGAVTVGLLAQSVLAGVKKLDVPCGGRDCSGGCQCFPEKGGRGQPGPVGPQGYTGPPGLQGF PGLQGRKGDKGERGAPGTTGPKGDVGPRGVSGYPGANGIPGHPGQGGPRGPPGYDGCNGTMGDAGSAGPQGPGGFLGPPG PQGPKGQKGEPYALPREERDKYRGEIGEPGLVGMQGPPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLGFYGEKG EKGDMGLQGPGGIPPDNGYVEKPTPLYELLPEQYKGEKGSGGEPGRIGISLKGEEGIMGFSGSRGAPGFDGEKGSPGQKG SRGLDGYQGSDGLPGPKGETGDPGPPGLPAYSPYPSVAKGVRGEPGSPGQPGEPGARGEPGDPGLPGRPGTSIGDEDEKR GLPGEMGPKGYTGERGFPAVYPGPPGTDGKPGLRGPPGRPGPPGPDGFLFGLKGARGSGGFPGSAGFPGARGQKGWKGDA GDCKCADQFIRGPPGLPGPKGFAGTNGQPGSKGSQGDPGQHGLPGFPGFKGAPGNVGPPGPKGMKGDSRTITTKGERGQP GVPGVPGLKGGDGIPGPPGLDGFHGLPGPPGDGIKGPPGDAGQPGAPGTKGLPGERGPPGLGLPGPKGERGFPGDAGLPG PPGFRGPPGLPGAPGQIDCDSGVKRPIGADGQETIQPGCVGGPKGSPGQPGLPGPPGAKGLRGVPGFSGADGVPGLKGLP GDPGREGFPGPPGFMGPRGSKGAVGPPGLDGLPGTSGLPGPVGPPGDRGLPGEVLGAQPGPRGDSGLPGRPGLKGPPGER GAPGFRGSQGMPGMPGQKGQPGSPGLSGQPGLPGPPGLHGFPGAPGREGPLGPLGAPGFEGLPGDRGEPGDTGVPGPVGM KGESGDRGDPGQQGARGHPGSPGFKGVSGMPGAPGLKGARGSPGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAG EPGVKGSRGDPGPPGPPPIILPGMKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGIPGLPGRPGHVKGVKGDIGIP GVPGSPGFPGVPGSPGIMGFQGFTGSRGDKGAPGTAGLFGEVGPTGDFGDIGDTIDLPGSPGLKGERGTTGAPGLKGFFG QKGAEGDVGFPGITGLAGVQGPPGFKGQTGFPGLTGLQGPQGDPGRAGAPGTKGDSGWPGNPGLPGLPGLRGIGGLHGLP GSKGFPGSPGADLHGDLGFPGPAGDRGDPGEANTLPGPTGAPGQKGERGVPGGRGPMGSPGLQGFPGITPPSNISGSPGD VGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGTKGWVGDPGPQGRPGVFGLPGEKGPRGEPGFMGNIGPTG SVGDRGPKGPKGDRGLPGAPGPVGAPGIAGIPQRIVVERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGR GGMSANPGFRGDQGPMGLQGPVGFEGEPGRPGSPGLPGMPGRSISIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEG QEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYASRNDKSYWLSTTAPLPMMPVAEEDIRPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYTNKYSFWLTTIPEQ TFQGTPSADTLKAGLIRTHISRCQVCMKNL >KYO41305.1 hypothetical protein Y1Q_0006157 [Alligator mississippiensis] MYRTEPCMIEMGQPSCSPCHHVQCWLELCATRMMMQVLLLLMLTTLLTGRVQAGGKTYTGPCAGRDCSGGCQCFPEKGSR GQPGPLGPQGFPGPPGLIGIPGLEGPKGHKGERGQPGITGPKGDQGLRGVTGFPGADGVPGHPGQPGSRGKPGHDGCNGT TGDPGEQGILGPPGQFGFIGAQGPKGQKGEPYVFPPEIADKYRGEMGKPGIKGFQGPRGEPGLVGFIGPKGRPGKPGPPG LPGPQGEKGNRGLGFYGKKGEKGEIGSEGPPGLPSTGEFTTSTDFSIDHCKGQQGMKGEKGEPGISGSHASRAEKGEEGI MGFPGQRGLPGINGIPGPVGEAGPPGFYGSPGYDGPKGMKGEQGEKGIPGLPAYVPYPIPRKGVRGDQGVTGFPGPRGDL GEKGNPGIPGRPGTSDGLDGLDKRGLPGEMGPKGYKGEPGFSALYPGIPGFPGQPGPKGFPGPAGPKGSLSISFGLKGRR GDPGAAGSRGFPGPRGDKGFKGETGDCKCTGSDEVRKSSAGLPGPPGFQGPPGEPGRKGEPGDQGQHGIPGFPGAKGFPG ETGYPGPRGQKGYSVYITTKGSKGDPGDPGLAGVQGSKGAKGIPGDPGLDGLQGLKGFPGDPGQEGLPGPPGFHGPRGER GPSGLLGQQGDDGISGKPGLPGPDGPKGVAGEVLGASAGSIGDVGLPGLPGLKGPPGNQGVPGLQGAGGIPGSPGSKGEP GLQGPHGLIGLPGEPGSHGFPGIPGHQGPAGRGGITGNIGSPGARGDHGEQGFPGPVGMKGLSGDKGELGIPGVQGIPGK TGLPGIDGMHGLQGYKGAKGSPGIEGFKGMTGNRGFQGHKGVKGEIGFFGISGLKGEQGNPGSKGDRGEQGEPGKPPKID PSMLVEVKGEKGDSGQTGLKGDSGFKGLKGMPGLPGEPGFPGFPGQPSHVSGAKGDIGSKGVTGSLGYPGQPGSPGIRGF PGSTGIRGEKGTEGFTGLYGESGLPGESGTPGDTINLPGIPGLKGEVGTPGSSGVRGSPGEKGQRGDPGFSGIEGLKGSQ GLPGIKGQSGFPGLVGPPGQQGDPGAPGLPGEKGTQGWPGFAGPTGLPGLRGISGLDGLPGTKGLQGSPGLDDYGPSGFP GGPGDKGQVGDPSTLEGARGGPGQKGERGNQGERGPTGSPGLDGIPGPPGVSNISGIRGDIGSPGLYGVPGYKGEQGRRG IPSPPGSKGEIGQIGVVGEDGPKGTRGDPGLTGKPGILGSFGAKGQKGEQGVMGPVGTLGISGDTGPAGPKGNRGVTGIQ GPPGSPGLTPLPSKTLAEVGAPGPHGQRGPQGIPGEIGPQGPLGDSGFRGAPGKQGLQGRSGIPALPGFRGDQGPQGHQG PSGSEGIPGRPGSPGLPGMPGRSVNIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFS TMPFLYCNPGDVCYYANRNDKSYWLSTTAPLPMMPVAEEEIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPEGWRSLWIG YSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIEEQFQSTPSADTLKAGLIRTHIS RCQVCMKNL >XP_018105335.1 collagen alpha-2(IV) chain isoform X1 [Xenopus laevis] MTRTQSTKRCATGSKEYSYFLLKHHPVTWCVLLVVLVTVFAGNAHAGGKSYTGPCGGRDCSQGCQCLPEKGSRGQPGPLG AQGTPGPPGLIGIAGLQGHKGDKGERGFTGVTGPSGDKGHRGVTGFAGADGVPGHTGQGGPRGKPGHDGCNGTKGDGGDG GSHGPRGPPGIPGGFGAKGQKGDPFHVSIEVKNRLKGDPGEPGFNGIQGPRGFPGIAGFIGPQGNRGPRGPPGPPGPQGS QGNRGLGYYGEKGETGDPGPPGEQSGPGVREQQHKNEILLLQYKGATGDQGEKGIPGDEGQQAFTGEKGEEGITGFPGQR GLPGIDGARGASGEIGFPGTNGVPGLPGQNGKKGDHGERGPQGPVTYVNGQKTGKGYEGDIGFPGQDGLYGDEGDLGDPG FPGQKGFPSTFPGPTGDTGLKGQRGPKGYPGDPGLPAFQPGPPGIDGDPGKEGPPGKPGYPGGRIGMKGLPGPPGRDGHR GFPGSRGFKGNKGEQGECKCFAGDESSKGPAGEPGPVGFPGLQGLSGRKGETGDRGVPGLPGTPGTVGPAGPAGLPGPAG EKGDKVFATEKGSKGVQGDPGVPGIPGHVGYPGRNGKDGIPGFPGPPGDGVKGLPGHAGFPGQPGIAGARGETGFPGPGF PGPKGMRGDSGDRGVSGFPGIPGLPGPQGDCYQETDEENKIGKEGTGCRLIAPPAPTGSPGPPGLPGYNGLRGQKGFPGP QGFDGVFGLKGVKGDPGNDSLPGPPGFPGQRGDRGNAGFPGQPGAPGLSGKPGLKGVQGEKGVAGDRLGAPPGEQGDTGL PGLQGLKGKQGDQGIPGLQGNFGTPGTPGNKGIQGSVGAPGAPGIPGPAALFGFPGIPGNPGMLGPQGSMGPPGPPGPRG DEGEKGPPGPVGMKGLPGEPGDQGFVGVRGKQGAPGIPGLVGMHGLPGVKGIKGSPGMEGFHGMKGVKGRPAWRGIKGPS GNIGFPGIKGREGIPGAKGDRGERGPPGESPQMLPEIMLLVKGEKGDQGVPGFKGTTGPKGSKGMPGNPGQPGTPGLPGI PSFEFGDKGEIGSPGPVGHPGIPGEGGPRGIIGFPGFTGPRGTPGFSGLPGVPGERGSYGDTGERGDTIDLPGEEGVKGQ VGIPGLPGQHGIPGEKGIKGDQGVQGIEGMKGEPGQPGERGFPGQQGLVGLPGSQGSPGLPGVHGEKGSAGFPGFPGQHG FPGTRGIAGLDGLPGTKGIQGQPGAEITGLKGFKGLSGERGQPGEASSIVGTPGPAGLKGTKGDQGLPGLIGITGTVGVR GLPGFSNRTGTPGDVGFPGPPGLPGFPGPMGIPGLPSKPGVKGEIGELGSQGDYGAKGIPGDQGKLGATGVAGMPGVKGW KGNAGFHGVVGESGHPGDQGPKGYKGDKGEHGFKGPPGQPGPVSEPPLATAEHGSPGPQGIIGPEGVRGDIGPKGVVGSP GAPGQTGKEGLPGIPGWSAPPGNRGELGLMGQRGLDGLKGDSGVPGRAGLPGMPGRSVNIGYLLVKHSQTDEEPMCPVGM AQLWTGYSLLYFEGQEKAHNQDLGLAGSCLQRFSTMPFLYCNPGDVCYYANRNDKSYWLSTTVPLPMMPVVEEEIRPYIS RCSVCEAPAVAIAVHSQDVSIPHCPDGWRSLWIGYSFLMHTAAGDEGGGQSLASPGSCLEDFRATPFIECNGGRGTCHYF ANKYSFWLTTIDQPFQSSPSADTLKAGLIQTHISRCQVCMKNL
Mafft alignment of selected proteins >sp|P08572|CO4A2_HUMAN Collagen alpha-2(IV) chain OS=Homo sapiens OX=9606 GN=COL4A2 PE=1 SV=4 M------------------GRDQRAVAGPA-------------LRRW-LLLGTVTVGFLA QSVLAGVK-KFDVPCGGRDCS---GGC--QCYPEKGGRGQPGPVGPQGYNGPPGLQGFPG LQGRKGDKGERGAPGVTGPKGDVGARGVSGFPG---ADGIPGHPGQGGPRGRPGYDGCNG TQGDSGPQGPPGSEGFTGPPG-PQGPKGQKGEPYALP--KEERDRYRGEPGEPGLVGFQG PPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLG--FYGVKGEKGDVGQPGPNGIP SDTLHP------------IIAPTGVTFHPDQYKGEKGSEGEPGIRGI------------- ---------SLKGEEGIMGFPGLRGY---PGLSGEKGSPGQKGSRGLDGYQGPDGPRGPK GEAGDPGP------------PGLPA----YSPHPSLAK----------GARGDPGFPGAQ GEPGSQGEPGDPGLPGPPGLSIG------------------DGDQRRGLPGEMGPKGFIG DPGIPAL-YGGPPGPDGK---RGPPGPPGLPGPPGPDG---------------FLFGLKG AKGRAGFPGLPGSPGARGPKGWKGDAG-EC-RCTE---GDEAIKGLPGLP---GPKGFAG INGEPGRKGDRGDPGQHGL---PGFPGLKGVPGNIGAPGPKGAKGDSR---TITTKGERG QPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGD-------------GIKGPPGDPGYPG IPGTKGTPGEMG------PPGLGLPGLKGQRGFPGDAGLP--GPPGFLGPPGPAGTPGQI DC--DTDVKRAVGGDRQEAIQP--GC----IGGPKGLPGLPGPPGPTGAKGLR---GIPG FAGADGGPGPRG--LPGDAGREG--FPGPPGFIGPRGSKGAV---GLPGPDGSPGPIGLP GPDGPPGERGLPGEVLGAQ-PGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLK GQPGLPGPSGQPGLYGPPGLH--GFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPG P------VGMKGLSGDRGDAGFTGEQGHP--------GSPGFKGIDGMPGTPGLKGDRGS PGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPP--VI LPG-MKDIKGEKGDEGPMGLKGYLGAKGIQGMP-GIPGLSGIP--GLPGRPGHIK-GVKG DIGVPGIPGLPGFPGVA---------GPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATG DFGDIG--DTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIG------------FPG ITGVTGVQGPPGL---------KGQTGFPGLTGPPG----SQGELGRIGLPGGKGDDGWP GAPGLPGFPGLRGIRGLHGLPGT------KGFPGSPGSDI----HGDPGFPGPPGERGDP GEANT--LPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPP---SNISGAPGDKGAP GIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDS------GPQGRPGVF GLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGI-PQKIA- --------VQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPG FRGDEG------PIGHQGPIGQE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GAPGRPGSPGLPGMPGR----SV SIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYASRNDKSYWLSTTAPL-P--MM-PVAEDEIKPYISRCSVCEAPAIAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGR GTCHYYANKYSFWLTTIPEQSFQ-GSPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >tr|A0A0H2UKP2|A0A0H2UKP2_DANRE Collagen, type IV, alpha 2 OS=Danio rerio OX=7955 GN=col4a2 PE=1 SV=2 EGE------------NIII-----------------------HINTFRSFTLIITVVILT STTFSGVK-KSTGPCGGRDCS---GGC--QCYPEKGARGLPGPLGPQGPTGPKGRQGEPG LQGPKGMKGEHGEAGFVGPKGSVGMEGVPGFNG---ADGVPGHPGPSGARGKAGPDGCNG TRGDSGMPGFPGLEGGQGTPG-WPGMKGEKGDPLEVW---VYMERFRGDPGPAGFPGIVG PTGDPGYRGLPGFQGPWG---PQGLKGAKGQKGERTKI--LKGVKGELGEIGEPGPPGVF SQTSP----------------------IPSDWQGEKGKMGSKGDKGDLGYL--------- ---------STKAESGVSGFAGARGN---PGLDGWPGPRGDTGLPGF---PGNNGRKGDV GEPGELVG----------------------SPFDDTGV-------------GPPGPPGER GPVGNYGRKGAKGQPGPPGPPPYG-------------QQTVELWGPEGPRGPKGASGETG EPGNPAT-QPGPPGPDGS---PGSVGPPGPKG--------------------------SL EEYFKGSPGHRGRPGSAGKKGPKGDHG-LC-ECSV-----KPPPGPPGPP---GDSGDPG MAGEWGQQGDQGDPGTKGA---NGLPGF---PGTEGLPGPKGRKGELM---EAVQKGSAG DPGDPGHSGFPGEQGRPGIDGRDGEPGFRGPPGE-------------GPVGEPGAKGYSG PPGRSGLIGPKG------NPGQVLGATKGLSGLPGDDGQT--GPDGRTGPPGPPG----- DC-------SSRG-GSQWSIPV--EC--IGDPGPPGESGLPGPRGLEGFPGVP---GPKG TAGFSGDLGDKG--ERGEPGRGG--PPGPKGFTGPRGDLGYP---GTKGVKGPPGLSGKP GLDGASGGKGEHGEVFGAS-SGAPGDPGLPGHRGDTGLTGDPGLPGYFGMEGMPGMTGLK GESGPPGLQGEQGRPGPPGTF--GFPGQTGYTGPPGPPGNIGEPGPSGRRGDQGEPGLIG A------RGVKGAIGDPGNIGVTGNIGPP--------GDQGETGGPGFFGLPGLKGSKGG QGMTGFPGKTGERGLKGFSGTKGEIGLPGHQGAKGAPGSPGQKGDRGLTGPPGDKPVIHI TPHMKEVMKGSKGDHGNMGDPGFTGPRGTKGFP-GIPGGEGKD--GHPGEPSVVK-GVKG LPGEPGLEGPKGMPGPT---------GLPGIEGFPGMSGPKGNKGSSGAYGRPGDSGIKG FKGDLG--PTISLPGSTGLRGETGHPGSTGAKGLYGMPGERGSSG------------LDG IEGMKGYQGEPGT---------VGPPGSDGLQGFPG----SQGHKGRSGDPGQTGTTGIQ GQPGQKGFPGLKGIFGLDGLKGQ------KGNQGVPGTDN----WGQPGNPGTKGELGET GIPST--TTGVPGSLGHKGTTGDSGNKGEIGQRGVPGPQGQQGF---SDIKGTQGDYGFP GIKGIPGFPGTRGTPGIPSPFGAKGDRGNVGDFGLFGEKGVQGDR------GEKGSSGES GVSGRKGDKGEPGMMGFPGRRGFQGDRGPFGPKGDTGPPGFPGLPGAKGYPPV-PQKLP- --------GEQGPPGQMGIQGPSGRNGNPGPAGPPGDSGFVGPSGHKGMPGLPGIPGSPG FRGEPG------SMGHSGLQGEQ------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GTRGRPGMPGPLGMAGR----SV NVGYLLVKHSQSEEIPMCPQGMSLLWMGYSLLYFEGQEKAHNQDLGLAGSCLPRFNTMPF LYCNPGDICYYASRNDKSYWLSTTQPI-P--MM-PVEESEIKPYISRCSVCEAPSVAIAV HSQDTTIPNCPVGWRSLWIGYSFLMHTAAGDEGGGQSLASPGSCLEDFRTTPFIECNGAK GTCHYFANKHSFWLTSI-DESFQ-SSPSSETLKAGQLLSRISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >NP_034062.3 collagen alpha-2(IV) chain precursor [Mus musculus] M------------------DRVRFKASGPP-------------LRGW-LLLATVTVGLLA QSVLGGVK-KLDVPCGGRDCS---GGC--QCYPEKGARGQPGAVGPQGYNGPPGLQGFPG LQGRKGDKGERGVPGPTGPKGDVGARGVSGFPG---ADGIPGHPGQGGPRGRPGYDGCNG TRGDAGPQGPSGSGGFPGLPG-PQGPKGQKGEPYALS--KEDRDKYRGEPGEPGLVGYQG PPGRPGPIGQMGPMGAPGRPGPPGPPGPKGQPGNRGLG--FYGQKGEKGDIGQPGPNGIP SDIT--------------LVGPTTSTIHPDLYKGEKGDEGEQGIPGV------------- ---------ISKGEEGIMGFPGIRGF---PGLDGEKGVVGQKGSRGLDGFQGPSGPRGPK GERGEQGP------------PGPSV----YSPHPSLAK----------GARGDPGFQGAH GEPGSRGEPGEPGTAGPPGPSVG------------------DEDSMRGLPGEMGPKGFSG EPGSPAR-YLGPPGADGR---PGPQGVPGPAGPPGPDG---------------FLFGLKG SEGRVGYPGPSGFPGTRGQKGWKGEAG-DC-QCG------QVIGGLPGLP---GPKGFPG VNGELGKKGDQGDPGLHGI---PGFPGFKGAPGVAGAPGPKGIKGDSR---TITTKGERG QPGIPGVHGMKGDDGVPGRDGLDGFPGLPGPPGD-------------GIKGPPGDAGLPG VPGTKGFPGDIG------PPGQGLPGPKGERGFPGDAGLP--GPPGFPGPPGPPGTPGQR DC--DTGVKRPIGGGQQVVVQP--GC----IEGPTGSPGQPGPPGPTGAKGVR---GMPG FPGASGEQGLKG--FPGDPGREG--FPGPPGFMGPRGSKGTT---GLPGPDGPPGPIGLP GPAGPPGDRGIPGEVLGAQ-PGTRGDAGLPGQPGLKGLPGETGAPGFRGSQGMPGMPGLK GQPGFPGPSGQPGQSGPPGQH--GFPGTPGREGPLGQPGSPGLGGLPGDRGEPGDPGVPG P------VGMKGLSGDRGDAGMSGERGHP--------GSPGFKGMAGMPGIPGQKGDRGS PGMDGFQGMLGLKGRQGFPGTKGEAGFFGVPGLKGLPGEPGVKGNRGDRGPPGPPP--LI LPG-MKDIKGEKGDEGPMGLKGYLGLKGIQGMP-GVPGVSGFP--GLPGRPGFIK-GVKG DIGVPGTPGLPGFPGVS---------GPPGITGFPGFTGSRGEKGTPGVAGVFGETGPTG DFGDIG--DTVDLPGSPGLKGERGITGIPGLKGFFGEKGAAGDIG------------FPG ITGMAGAQGSPGL---------KGQTGFPGLTGLQG----PQGEPGRIGIPGDKGDFGWP GVPGLPGFPGIRGISGLHGLPGT------KGFPGSPGVDA----HGDPGFPGPTGDRGDR GEANT--LPGPVGVPGQKGERGTPGERGPAGSPGLQGFPGISPP---SNISGSPGDVGAP GIFGLQGYQGPPGPPGPNALPGIKGDEGSSGAAGFPGQKGWVGDP------GPQGQPGVL GLPGEKGPKGEQGFMGNTGPSGAVGDRGPKGPKGDQGFPGAPGSMGSPGIPGI-PQKIA- --------VQPGTLGPQGRRGLPGALGEIGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPG FRGDQG------PMGHQGPVGQE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GEPGRPGSPGLPGMPGR----SV SIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYASRNDKSYWLSTTAPL-P--MM-PVAEEEIKPYISRCSVCEAPAVAIAV HSQDTSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGR GTCHYFANKYSFWLTTIPEQNFQ-STPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_038951185.1 collagen alpha-2(IV) chain [Rattus norvegicus] M------------------DRVRFSASGLP-------------LRGW-LLLATVTVGLLA QSVLGGVK-KSDVPCGGRDCS---GGC--QCFPEKGARGQPGEVGPQGYNGPPGLQGFPG LQGRKGDKGERGAPGPTGPKGDVGARGVSGFPG---ADGIPGHPGQGGPRGRPGYDGCNG TRGDAGPQGPSGTGGFPGLPG-PQGPKGQKGEPYALS--KEDRDKYRGEPGEPGSVGYQG PPGRPGPIGQMGPMGAPGRPGPPGPPGPKGQPGNRGLG--FYGEKGEKGDVGQPGPNGIP SDIT--------------LIGPTPSTYHPDMYKGEKGSQGEPGIPGI------------- ---------TLKGEEGIMGFPGTRGF---PGLDGEKGVSGQKGSRGLDGFQGPSGPRGPK GERGELGP------------PGPPA----YSPHPSLAK----------GARGDPGFQGAH GEPGSRGEPGDPGPVGPPGLSIG------------------DEDSKRGLPGEMGPKGFSG EPGPSAY-YPGPPGADGK---PGPQGLPGPAGPPGPDG---------------FLFGLKG SEGRVGYPGPSGFPGGRGQKGWKGEAG-DC-QCG------QVIPGLPGLP---GPKGFPG VNGEFGKKGDQGDPGLHGI---PGFPGFKGAPGIAGAPGPKGVKGDSR---TITTKGERG QPGIPGVHGMKGDDGVPGRDGLDGFPGLPGPPGD-------------GIKGPPGDAGLPG TPGTKGFPGEVG------PPGQGLPGPKGERGFPGDAGLP--GPPGFPGPPGLPGTPGQA DC--DTGVKRPIGGGQQVVIQP--GC----VEGPAGSPGQPGPPGPTGAKGIR---GIPG FPGASGEQGLKG--FPGDPGREG--FPGPPGFMGPRGSKGAP---GLPGPDGPPGPIGLP GPAGPPGDRGIPGEVLGAQ-PGARGDAGLPGQPGLKGFPGEIGAPGFRGSQGMPGMPGLK GQPGFPGPSGQPGLSGPPGQH--GFPGAPGREGPLGLPGSPGLGGLPGDRGEPGEPGEPG P------VGMKGVSGDRGDAGVSGERGHP--------GSPGFKGMAGMPGIPGQKGDRGS PGMDGFQGMLGLKGRPGFPGIKGEAGFFGVPGLKGLPGEPGVKGNRGDRGPPGPPP--LI LPG-MKDIKGEKGDEGPMGLKGYLGLKGIQGMP-GVPGLSGIP--GLPGRPGFIK-GAKG DIGVPGTPGLPGFPGVS---------GPPGITGFPGFTGSRGEKGTPGVAGVFGETGPTG DFGDIG--DTVDLPGSPGLKGERGVTGIPGLKGLFGEKGAEGDVG------------FPG ITGMAGAQGSPGL---------KGQTGFPGLTGLQG----PQGEPGRIGIPGDKGDFGWP GVPGRPGIPGIRGISGLHGLPGT------KGFPGSPGVDA----HGDPGFPGPTGDRGDR GEANT--LPGPVGAPGQKGEQGIPGERGPVGSPGLQGFPGISPP---SNISGLPGDVGAP GIFGLQGYQGPPGPPGPNALPGIKGDEGSSGAAGFPGEKGWVGDP------GPQGQPGVH GLPGEKGPKGEQGFMGNTGPSGAVGDRGPKGPKGDQGFPGAPGSMGSPGIPGI-PQKIA- --------VQPGTMGPQGRRGLPGALGEMGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPG FRGDQG------PMGHQGPIGQE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GEPGRPGSPGLPGMPGR----SV SIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYASRNDKSYWLSTTAPL-P--MM-PVAEEEIKPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGR GTCHYFANKYSFWLTTIPEQNFQ-STPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_038287383.1 collagen alpha-2(IV) chain isoform X1 [Canis lupus familiaris] M------------------DRPRCSAHSPA-------------LRRW-LLLGAVTVGLLA QSVLAGVK-KFDVPCGGRDCS---GGC--QCYPEKGGRGQPGPVGPQGYTGPPGLQGFPG LQGRKGDKGERGSPGITGPKGDVGARGVSGFPG---ADGIPGHPGQGGPRGPPGYDGCNG TRGDVGRQGPEGPAGFLGPPG-PQGPKGQKGEPYALS--SVDRDKYRGEPGEPGLVGFQG PPGRPGPIGQMGPVGAPGRPGPPGPPGPKGQPGNRGLG--FYGEKGEKGDMGLPGPNGIP SDTHHA------------IIGPMKEMFHPDQYKGEKGSEGEPGRKGI------------- ---------SLKGEEGIMGFSGTRGA---PGYDGEKGSPGQKGSRGLDGYQGPDGPPGPK GEAGDRGP------------PGAPA----YFPHPSQVK----------GARGDPGFPGTH GDPGSRGEPGDPGPPGLPGPSIR------------------DEDGKRGLPGEMGPKGFIG DPGIPAP-YPGPPGTDGK---PGLRGPPGAAGPPGPDG---------------FLFGLKG TEGSAGFPGPSGFPGARGQKGWKGDAG-DC-KCAE---GDQFVGGLPGLP---GPKGFPG INGEPGRKGSQGDPGQHGI---PGFPGFKGAPGTVGPPGPKGLKGDSR---AITTKGERG QPGVPGVPGLKGDDGVPGRDGLDGFPGLPGPPGD-------------GIKGPPGDSGYPG APGTKGAPGERG------PPGLGLPGPKGERGFPGDAGLP--GPPGFPGPPGPPGTPGQI DC--DTGVKRPIGGDGQEAVQP--DC----VRGPMGSPGLPGPPGPTGAKGLQ---GIPG LSGADGTPGLRG--LPGDPGREG--FPGPPGFVGPRGSKGAV---GLPGPDGHPGPTGLP GPVGPPGDRGLPGEVLGAQ-PGPRGDAGLPGHPGLKGPPGERGPPGFRGSQGMPGMPGLK GQPGFPGPSGQPGLPGPPGQH--GFPGAPGREGPLGLPGASGRGGLPGDRGDPGDTGVPG P------VGMKGLSGDRGDPGLLGERGPP--------GSPGFKGMSGMPGIPGQKGGRGS PGMDGFQGMVGLKGRPGLPGNKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPP--II QPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMP-GIPGLSGVP--GLPGKPGHIK-GIKG DIGIPGVPGLPGFPGVP---------GPPGIIGFPGFTGSRGDKGAPGRAGLYGEVGPTG DFGDSG--DIINLPGSPGLKGERGIAGAPGLKGFFGEKGTEGEVG------------FPG ITGVPGVQGPPGP---------KGQTGFPGLTGLQG----PQGDPGRAGVPGNKGDYGWP GIPGSPGFPGIRGISGLHGLPGT------KGLPGSPGADI----HGDPGFPGPAGDRGDP GEANI--RPGPIGAPGQKGERGDPGGRGPIGSPGLQGFPGITPP---SNMSGLPGDKGAP GIFGLEGYRGPPGPPGPAALPGSKGDEGNPGAPGTPGTKGWGGDP------GPQGRPGVF GLPGEKGPRGEPGFMGNTGATGSVGDRGPKGPKGDRGLPGAPGSVGSPGIAGI-PQKIT- --------IQPGPVGPQGRRGPPGMQGEMGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPG FRGDQG------PMGHQGPVGQE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GEPGRPGTPGLPGMPGR----SV SIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYASRNDKSYWLSTTAPL-P--MM-PVAEDDIKPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGR GTCHYYANKYSFWLTTIPEQSFQ-GSPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >NP_001155862.1 collagen alpha-2(IV) chain precursor [Gallus gallus] M------------------DLSPLPGARVS------------VCQDVGLLLVLLEVVLSA GRVDAGGK-SYTGPCGGRDCS---GGC--QCFPEKGARGQPGILGSQGFPGPPGLMGIPG LQGPKGHKGERGHPGISGPKGETGQRGVTGFPG---ADGVPGHPGQPGSRGKPGHDGCNG TVGDPGDPGTPGHSGFPGTIG-VQGPKGQKGEPYVLP--PDIASRHRGDPGDPGFTGFPG APGTLGIQGPIGPRGVPGRPGPPGSPGPQGPQGNRGLG--FYGEKGEQGSPGPPGPPGLP TRELIG--------------------VPTDKHKGERGEPGQKGEAGFPGVL--------- ------LFAPEKGEEGVMGFPGQRGL---PGNDGFPGLSGERGFPGFDGQPGQYGPRGGK GEQGEMGP------------PGPPA----YVPYRIPRK----------GVRGDPGSPGAS GLRGEQGEQGDRGLPGIPGFSDG-------------------DADKPGLPGEIGPKGEKG EEGSPAY-QAGPPGFPGKHGEPGIRGPPGPPGTPG------------------SLFGLKG QEGTPGRPGVQGFPGPRGQRGPKGEEG-DCSKCLL---SDELRRGSTGPR---GPPGFPG TPGQPGRKGEPGDQGPHGI---PGYAGAKGQSGQEGLPGPKGEKGDSI---YITTKGTKG IRGDPGLPGIRGEDGFPGRDGLDGLPGLPGLPGD-------------GIRGLPGDPGYPG ELGPKGFPGEIG------LPGEGYPGPKGYRGLPGDRGTD--GHPGPPGLPGPPGEPGQL DC--GQVIEDFSRGEATDPIWSGGGC----VRPPKGSQGNPGLPGATGTKGAR---GFPG DPGPVGFPGLNG--TRGDPGREG--YPGPPGFIGPRGDRGPN---GLPGLQGHPGLMGKS GAPGLAGQKGAPGDVLGAA-AGPRGDDGLPGFPGLKGAPGDQGIPGIRGADGNPGLPGPK GDPGLQGLPGLMGLPGTPGTH--GFPGPPGNRGPDGGPGSQGPLGPPGARGEDGEQGFPG P------VGMKGLSGDKGETGFPGLQGIP--------GVTGPPGISGMDGFPGDKGSRGS PGIDGFKGMPGLKGRPGIKGIKGEFGLLGTRGDKGAQGARGFKGDRGEQGPPGEPP--KL KPSMMMEVKGEKGDAGETGTKGFFGIKGSKGMP-GLPGKTGIP--GSPGHPSYVP-GVKG DIGAKGLTGLKGYPGPT---------GSPGIRGFPGSTGGRGDKGAPGISGHFGTPGSHG EIGEPG--DTINLPGMPGLKGEVGVPGLTGLRGGPGQKGEGGDPG------------LPG IEGLKGIQGVPGS---------LGQKGLPGLVGPPG----QQGSPGTPGFQGEKGAPGWP GLPGQAGLPGLRGISGLHGLPGT------KGLPGSPGPDG----YGSAGFPGPVGDKGEA GEPSR--VEGSQGPPGQKGDRGVPGVQGPFGIPGQDGLPGPPGI---SNISGYPGDTGSP GLDGVPGYPGLHGQPGIPAPPGSKGESGRAGVSGQAGPKGTRGDP------GLPGRPGIP GYPGPKGRKGEQGVIGFIGTVGFPGDLGPIGPKGDRGLTGFQGPPGSPGLPPI-PPRLV- --------AEQGSPGPRGNAGPRGSPGDAGPQGPPGEPGLRGLPGEPGLQGRGGIPAPPG SRGEQG------AMGFQGPVGFE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GQPGRPGSPGLPGMPGR----SV SIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDICYYANRNDKSYWLSTTAPL-P--MM-PVAEEEIRPYISRCSVCEAPAVAIAV HSQEASIPRCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGAR GTCHYFANKYSFWLTTI-DQPFQ-SKPSADTLKAGLIRSHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_024204109.1 collagen alpha-2(IV) chain isoform X1 [Pan troglodytes] M------------------GRDQRAVAGPA-------------LRRW--LLGTVTVGFLA QSVLAGVK-KFDVPCGGRDCS---GGC--QCYPEKGGRGQPGPVGPQGYNGPPGLQGFPG LQGRKGDKGERGAPGITGPKGDVGARGVSGFPG---ADGIPGHPGQGGPRGRPGYDGCNG TQGDSGPQGPPGSEGFTGPPG-PQGPKGQKGEPYALP--KEERDRYRGEPGEPGLVGFQG PPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLG--FYGVKGEKGDVGQPGPNGIP SDLLHP------------IIAPTGVTFHPDQYKGEKGSEGEPGIRGI------------- ---------SLKGEEGIMGFPGLRGY---PGLSGEKGSPGQKGSRGLDGYQGPDGPRGPK GEAGDPGP------------PGLPA----YSPHPSLAK----------GARGDPGFPGAQ GEPGSQGEPGDPGLPGAPGLSIG------------------DGDQRRGLPGEMGPKGFIG DPGIPAL-YGGPPGPDGK---RGPPGPPGLPGPPGPDG---------------FLFGLKG AKGRAGFPGLPGSPGARGPKGWKGDAG-EC-RCTE---GDEAIKGLPGLP---GPKGFAG INGEPGRKGDKGDPGQHGL---PGFPGLKGVPGNVGAPGPKGAKGDSR---TITTKGERG QPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGD-------------GIKGPPGDPGYPG IPGTKGTPGEMG------PPGLGLPGLKGQRGFPGDAGLP--GPPGFLGPPGPAGTPGQI DC--DTDVKRAIGGDRQEAIQP--GC----VGGPKGLPGLPGPPGPTGAKGLR---GIPG FSGADGGPGPKG--LPGDAGREG--FPGPPGFIGPRGSKGAV---GLPGPDGSPGPIGLP GPDGPPGERGLPGEVLGAQ-PGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLK GQPGLPGPSGQPGLYGPPGLH--GFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPG P------VGMKGLSGDRGDAGFTGERGHP--------GSPGFKGIDGMPGTPGLKGDRGS PGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPP--VI LPG-MKDIKGEKGDEGPMGLKGYLGAKGIQGMP-GIPGLSGIP--GLPGRPGHIK-GVKG DIGAPGIPGLPGFPGVA---------GPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATG DFGDIG--DTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIG------------FPG ITGVTGVQGPPGL---------KGQTGFPGLTGPPG----SQGEPGRIGLPGGKGDDGWP GAPGLPGFPGLRGIRGLHGLPGT------KGFPGSPGSDI----HGDPGFPGPPGERGDP GEANT--LPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPP---SNISGAPGDKGAP GIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDS------GPQGRPGVF GLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGI-PQKIA- --------VQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPG FRGDEG------PIGHQGPIGQEGAPGRLLSLFLGLQVHQAVHSLSLSGCRCTRLSTFSL SQAAGAPGRPLSLSRAVGAPGHPLSLFLGLQVHQAVHFLSLSGCRCTRPSTHSLSRAAGT PGCPLCLSLSRAAGAPGRPLSLFLGLQVHQAVHSLSFSGCRCTRPSTHSLSRAAGTPGCP LCLSLSRAAGAPGRPLSLSLSGCRCTRPSTLSLSRAAGAPGRPGSPGLPGMPGR----SV SIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYASRNDKSYWLSTTAPL-P--MM-PVAEDEIKPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGR GTCHYYANKYSFWLTTIPEQSFQ-GSPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_024855939.1 collagen alpha-2(IV) chain [Bos taurus] M------------------DRELRAAARPA-------------LRRW-LLLGAVTVGLLA QSVLAGVK-KLDVPCGGRDCS---GGC--QCYPEKGGRGQPGPVGPQGYTGPPGLQGFPG LQGRKGDKGQRGAPGITGPKGDVGPRGVSGFPG---ADGIPGHPGQGGPRGPPGYDGCNG TVGDSGYAGPPGPGGFLGPRG-PQGPKGQKGEPYALS--SEDRDKYRGEPGEPGLVGLQG PPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLG--FYGEKGEKGDMGLQGPGGIP PDNGYV------------EKPTPVYELLPEQYKGEKGSQGEPGRIGV------------- ---------SLKGEEGVVGFSGPRGA---PGIDSEKGLPGQKGSRGLDGYQGPDGLPGPK GERGDPGP------------PGPPA----YSPYPSVAK----------GVRGEPGSPGAP GEPGDRGVPGDPGLPGRPGTTIG------------------DEDEKRGLPGEMGPKGFTG EQGFPAL-YPGPPGTDGQ---PGLRGPPGLPGPPGPDG---------------FLFGLKG EKGSGGFPGSSGFPGARGQKGWKGDAG-DC-KCA-----DQFIRGPPGLP---GPKGFAG ANGQPGSKGSQGDPGQHGV---PGFAGFKGAPGNVGPPGPKGMKGDSR---TITTKGERG QPGVPGAPGLKGSDGIPGPPGLDGFHGLPGPPGD-------------GIKGPRGDTGQPG APGTKGLPGERG------PPGLGLPGPKGERGFPGDAGLP--GPPGFPGPPGLPGSPGQI DC--DSGVKRPIGADGQETIQP--GC----VGGPKGSPGQPGLPGPPGAKGLR---GIPG FSGADGAPGLKG--LPGDPGREG--FPGPPGFMGPRGSKGAV---GPPGLDGLPGASGLP GPVGPPGDRGLPGEVLGAQ-PGPRGDSGLPGRPGPKGPPGERGPPGFRGSQGMPGMPGQK GQPGSPGLSGQPGLPGPPGQH--GFPGAPGREGPLGPPGAPGFQGLPGDRGEPGDTGVPG P------VGMKGGSGDRGDPGQQGERGHP--------GHPGFKGVSGMPGAPGLKGARGS PGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPP--LI EPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMP-GIPGLSGIP--GLPGRPGQIK-GVKG DTGIPGVPGSPGFPGVP---------GSPGIMGFQGFTGSRGDKGVPGRAGLFGEVGPTG DFGDIG--DTIDLPGSPGLKGERGTTGIPGQKGFFGERGTEGDIG------------FPG ITGLAGVQGPPGF---------KGQKGFPGLTGLQG----PQGDPGRAGAPGIKGDSGWP GNPGLPGLPGLRGISGLHGLPGS------KGFPGSPGADV----HGDPGFPGPAGDKGDP GEPNT--LPGPTGAPGQKGERGAPGERGPIGSPGLQGFPGITPL---SNISGSPGDVGAP GIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGSPGTKGWIGDP------GPQGRPGVF GLPGEKGPKGEPGFMGNIGPTGSPGDRGPKGPKGDRGLPGAPGAVGTPGITGI-PQRIA- --------IERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGVSAIPG FRGDQG------PVGLQGPVGFE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GEPGRPGSPGLPGMPGR----SI SIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYASRNDKSYWLSTTAPL-P--MM-PVAEEDIRPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGAR GTCHYYANKYSFWLTTIPEQSFQ-GTPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_020921567.1 collagen alpha-2(IV) chain [Sus scrofa] M------------------DRDPRAASGPA-------------LRRW-LLLGTVMVGLLA QSVLAGVK-KLDVPCGGRDCS---GGC--QCYPEKGGRGQPGPVGPQGYTGPPGLQGFPG LQGRKGDKGERGAPGITGPKGDVGARGVSGFPG---ADGIPGHPGQGGPRGRPGSDGCNG TVGDTGYAGPVGPDGFLGPPG-PQGPKGQKGEPYALS--REDRDKYRGEPGEPGLVGFQG PPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLG--FYGEKGEKGDVGQPGPNGIP SDNHHP------------IIGPTRETIYLDQYKGEKGSEGEPGRKGI------------- ---------SLKGEEGIMGFSGSRGV---PGFDGEKGSPGQKGSRGLDGYEGPDGYPGPK GERGDPGP------------PGAPA----YSPHPSLAK----------GARGEPGFPGAL GEPGARGEPGDPGPPGLPGTSVR------------------DEDEKRGLPGEMGPKGYAG EPGAPAL-YPGPPGADGK---PGLRGPPGPPGPPGPDD---------------FLFGLKG AKGSMGYPGPSGFPGARGQKGWKGDAG-DC-KCAE---DDQFVGGLPGPP---GPKGFPG INGEPGRKGSQGDPGQHGI---PGFPGFKGAPGDAGPPGPKGMKGDSR---TITTKGERG QPGVPGVPGLRGDDGAPGRDGLDGFPGLPGPPGD-------------GIKGPPGDAGHPG VPGTKGLAGDRG------PPGLGLPGPKGERGFPGDDGLP--GPPGFPGPPGPPGPPGQI DC--DSGVKRPIGADGQEVIQP--GC----VGGPKGSPGQPGPPGPPGAKGLR---GIPG PSGADGAPGLKG--FPGDPGREG--FPGPPGFVGPRGSKGAV---GPPGLDGLPGPSGLP GPVGPPGDKGLPGEVLGAQ-PGSRGDPGLPGHPGLKGPPGERGAPGFRGSEGMPGMPGLK GQPGFPGPSGQPGLPGPPGQH--GFPGAPGREGPLGPPGAPGFGGLPGDRGDPGDTGVPG P------VGMKGLSGDRGDPGLLGERGHP--------GSPGFKGVAGMPGAPGPKGTRGS PGMHGFQGMLGLKGSPGLPGSKGEAGFFGVPGLKGLPGEPGVKGSRGDPGLPGPPP--TI LPG-MKDIKGEKGDEGPMGLKGYLGLKGIPGMP-GIPGLSGVP--GLPGKPGHVK-GAKG DTGAPGVPGSPGFPGLP---------GPPGIIGFPGFTGSRGDKGSPGRAGLYGEIGATG DFGDIG--DTIDLPGSPGLKGERGTAGVPGLKGFFGEKGTVGDVG------------FPG ITGLAGVQGPPGL---------KGQTGFPGLTGLQG----PQGDPGRAGVPGAKGELGWP GNVGLPGLPGIRGISGLHGLPGT------KGFPGSPGADV----HGDPGFPGPAGDRGDP GEANT--LPGPAGAPGQKGERGAPGERGPVGNPGLQGFPGITPP---SNVSGLPGDTGAP GIFGPEGYRGPPGPPGPAALPGSKGDEGLPGIPGNPGGKGWVGDP------GPQGRPGVF GLPGEKGPRGEQGFMGNTGATGSVGDRGPKGPKGDRGLPGPPGAVGAPGIVGI-PQRIA- --------VQRGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPG FRGDQG------PVGQQGPVGQE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GEPGRPGSPGLPGMPGR----SV SIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDICHYASRNDKSYWLSTTAPL-P--MM-PVAEEEIRPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGAR GTCHYYANKYSFWLTTIPEQSFQ-SSPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_008258402.1 PREDICTED: collagen alpha-2(IV) chain [Oryctolagus cuniculus] M------------------GRERRAASGSA-------------MRRW-LLLGAVTAGFLA QSVLAGVK-KSDVPCGGRDCS---GGC--QCYPEKGGRGQPGPVGPQGYTGPPGLQGFPG LQGRKGDKGERGAPGITGPKGDVGARGVSGFPG---ADGIPGHPGQGGPRGPPGYDGCNG TRGDEGPQGPSGTGGFPGSPGPPRTQRGRRVSPYALS--EEDRDRYRGEIGEPGLVGFQG PPGRPGPMGPMGPVGAPGRPGPPGPPGPKGHPGNRGLG--FYGKKGEKGDIGAPGPNGIP FDTIYP------------IVGPTKTTFHPDQYKGEKGSEGEPGAIGI------------- ---------SLKGEEGIMGFSGSRGA---PGLDGEKGSPGQKGSRGVDGYQGPDGPRGPK GQAGDPGP------------AGPPA----YSPHPSLAK----------GARGDPGFPGPH GDPGSRGEPGDPGPPGSPGLPVR------------------DEDEMRGLPGEMGPKGFAG EKGFPAL-YPGPPGVDGK---PGLPGVPGPAGPPGPDG---------------FLFGLKG AEGRVGYPGPSGFPGARGQKGWKGEAG-DC-KCLE---GDQFPGGLPGLP---GPKGVPG LNGEPGSKGQQGDPGQHGI---PGFPGFKGAPGLTGVPGPKGAKGDSR---TITTKGERG QPGVPGVPGMKGDDGVPGRDGLDGFPGLPGPPGD-------------GIRGPPGDAGYPG IPGTKGGPGDVG------PPGLGLPGPKGERGFPGDAGLP--GPPGFPGPPGPPGTPGQI DC--DTGVKRPPGGDGQEAVLP--GC----AAGPKGLPGPPGPPGPPGAKGLQ---GIPG FSGADGPPGLKG--LPGDPGREG--FPGPPGFVGPRGSKGAT---GLPGPDGRPGPVGLP GPAGAPGDRGLPGEVLGAQ-PGPRGDAGLPGQPGLKGLPGERGPPGFTGSQGMPGMPGLK GQLGLPGPSGQQGLQGPPGQH--GFPGAPGPAGPLGLPGAPGLEGLPGDRGEPGDTGVPG P------VGMKGLSGDRGDAGFSGERGQP--------GNPGFKGMSGMPGTPGPKGERGS PGMDGFQGMLGLKGRPGLPGTKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPP--II LPG-MKDIKGEKGDEGPMGLKGHLGLKGIQGNSRGVPWPGGNP-WGCLGRPGHIKRSRKA KLAVPGVPGLPGRAGVR---------GPSGHGAWPGIRGTRGDKGAPGIAGLYGELGPTG DFGDVG--DTIDLPGSPGLKGEQGSAGVPGLKGFFGEKGVEGEVG------------FPG ITGLTGAQGPPGL---------KGQTGFPGLTGLQG----PQGDPGRIGVPGDKGDRGWP GAPGLPGFPGIRGIGGLHGLPGT------KGFQGSPGADA----HGDPGFPGATGERGDP GEANL--LPGPLGVPGQKGERGVPGERGPAGSPGLQGFPGITPP---SNISGLPGDKGAA GIFGLQGYRGPPGPPGPAALPGSKGEDGSPGAAGVPGSKGWAGDP------GPQGRPGVF GLPGEKGPRGEQGFMGNTGATGAAGDRGPKGPKGDQGFPGAPGPVGSPGIIGLPPEDRC- --------PARGLWAPRERGGPPGAQGEIGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPG FRGDQG------PMGHQGPVGQE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GEPGRPGSPGLPGMPGR----SV SIGYLLVKHSQTEQEPMCPLGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYASRNDKSYWLSTTAPL-P--MM-PVAEDEIKPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGR GTCHYYANKYSFWLTTIPERSFQ-GSPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_024086739.1 collagen alpha-2(IV) chain [Pongo abelii] M------------------GRDQRAVAGPA-------------LRRW-LLLGTVTVGFLA QSVLAGVK-KFDVPCGGRDCS---GGC--QCYPEKGGRGQPGPVGPQGYNGPPGLQGFPG LQGRKGDKGERGAPGITGPKGDVGARGVSGFPG---ADGIPGHPGQGGPRGRPGYDGCNG TQGDSGPQGPPGSEGFTGPPG-PQGPKGQKGEPYALP--KEERDRYRGEPGEPGLVGFQG PPGRPGYVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLG--FYGVKGEKGDVGQPGPNGIP SDTLHP------------IIAPTRVTFHPDQYKGEKGSEGEPGIRGI------------- ---------SLKGEEGIMGFPGPRGY---PGLSGEKGSPGQKGSRGLDGYQGPDGPRGPK GEAGDPGP------------PGPPA----YSPHPSLAK----------GARGDPGFPGAQ GEPGSQGEPGDPGLPGPPGLSIG------------------DGDQRRGLPGEMGPKGFIG DPGIPAL-YGGPPGPDGK---RGPPGPPGLPGPPGPDG---------------FLFGLKG AEGGVGFPGLPGSPGARGPKGWKGDAG-DC-RCTE---GDEAIRGLPGLP---GPKGFAG INGEPGTKGDKGDPGQHGL---PGFPGLKGVPGNVGAPGPKGAKGDSR---TITTKGERG QPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGD-------------GIKGPPGDPGYPG IPGTKGTPGEMG------PPGLGLPGLKGQRGFPGDAGLP--GPPGFLGPPGPAGTPGQI DC--DTDVKRAIGGDRQEVIQP--GC----IGGPKGLPGLPGPPGPTGTKGLR---GIPG FSGADGGPGPKG--LPGDPGREG--FPGPPGFIGPRGSKGAV---GLPGPDGSPGPIGLP GPDGPPGERGLPGEVLGAQ-PGPRGDAGVPGQPGLKGLPGDRGSPGFRGSQGMPGMPGLK GQPGLPGPSGQPGLYGPPGLH--GFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPG P------VGMKGLSGDRGDAGFTGERGHP--------GSPGFKGIDGMPGTPGLKGDRGS PGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPP--VI LPG-MKDIKGEKGDEGPMGLKGYLGAKGIQGMP-GIPGLSGIP--GLPGRPGHIK-GVKG DIGAPGIPGLPGFPGVA---------GPPGITGFPGFIGSRGDKGAPGRAGLYGEIGPTG DFGDIG--DTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIG------------FPG ITGVTGVQGPPGL---------KGQTGFPGLTGPPG----SQGESGRIGLPGGKGDDGWP GAPGLPGFPGLRGIRGLHGLPGT------KGFPGSPGADI----HGDPGFPGPPGERGEP GEANT--LPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPP---SNISGVPGDKGAP GIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDA------GPQGRPGVF GLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGI-PQKIA- --------VQPGTVGPQGRRGHPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPG FRGDEG------PIGHQGPIGQE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GAPGRPGSPGLPGMPGR----SV SIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYASRNDKSYWLSTTAPL-P--MM-PVAEDEIKPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGR GTCHYYANKYSFWLTTIPEQSFQ-GSPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_010726857.1 collagen alpha-2(IV) chain [Meleagris gallopavo] M------------------DLSPLPGARVF------------VCQDAGLLLVLLEVVLLA GRVDAGGK-SYTGPCGGRDCS---GGC--QCFPEKGARGQPGNLGSQGLPGPPGLMGIPG LQGPKGHKGERGHPGISGPKGEMGLRGVTGFPG---ADGIPGHPGQPGSRGKPGHDGCNG TVGDPGDPGTPGHSGFPGTIG-VQGPKGQKGEPYVLP--PDIASQYRGEPGDPGLTGFPG APGRLGIQGPIGPRGTPGRPGPPGPPGPQGPQGNRGLG--FYGEKGEQGSPGPPGPPGLP TRELIG--------------------VPTDKHKGERGEPGLKGEAGFPGVL--------- ------LFTPEKGEEGVMGFPGQRGL---PGNDGFPGLSGERGFPGFDGQPGQYGPRGGK GEQGEMGP------------PGPPA----YVPYRIPRK----------GVRGDPGFPGAS GLQGEPGEQGDRGLPGIPGFSDG-------------------DADKPGLPGEIGPKGEKG EEGSPAY-QAGPPGFPGKHGEPGPRGPPGPPGTPG------------------SLFGLKG QEGTPGRPGAQGFPGPRGQRGPKGEEG-DCSKCLL---SDELRRGSTGPR---GPPGFPG TPGQPGRKGEPGDQGPHGI---PGYAGAKGQSGQEGFPGPKGEKGDSI---YITTKGTKG IRGDPGLPGIRGEDGFPGRDGLDGLPGLPGLPGD-------------GIRGLPGDPGYPG ELGPKGFPGETG------LPGGGFPGPKGYRGPPGDHGTQ--GNPGIPGLPGPPGEPGQI DC--GQVIEDFPRGDATDPIWSGGGC----VRPPKGSQGNPGLPGATGTKGAR---GFPG DPGPVGFPGLNG--TRGDPGREG--YPGPPGFIGPRGDSGPN---GLPGLQGHPGLMGKS GAPGLDGQKGAPGDVLGAA-AGPQGDAGLPGFPGLKGAPGDQGIPGIRGADGNPGLPGPK GDPGLQGLPGLMGLPGTPGTH--GFPGPPGNPGPDGGPGSQGPLGPPGARGEDGEQGFPG L------VGMKGQSGDKGETGFPGLQGIP--------GVTGPPGISGMDGFPGDKGSRGS PGIDGFKGMPGLKGRPGIKGIKGEFGLYGTRGDKGTKGAQGFKGDRGERGPPGEPP--KP KPSMMMKVKGEKGDAGETGTKGFFGIKGSKGMP-GLPGKTGIP--GSPGHPSYVP-GVKG DIGAKGLTGLKGYPGPT---------GSPGIRGFPGSTGGRGDKGAPGSSGHFGTPGSHG EIGEPG--DTINLPGMPGLKGEVGVPGLTGLRGGPGQKGEGGDPG------------LPG IEGLKGIQGVPGS---------LGQQGLPGLVGPPG----QQGSPGTPGFQGEKGTPGWP GLPGQAGLPGLRGIGGLHGLPGT------KGLPGSPGPDG----YGSAGFPGPVGDKGEA GEPSR--VQGSQGPPGQKGDRGVPGIQGPFGIPGQDGLPGLPGF---SNISGYPGDIGSP GLDGVPGYPGLHGQPGIPAPPGSKGESGRAGVSGQAGPKGTRGDP------GLQGRPGIP GYPGPKGRKGEQGVIGFIGTVGFPGDLGPIGPKGDRGLTGFQGPPGSPGLPPL-PPRLV- --------AEQGSPGPRGSAGPQGSPGDIGPQGPPGEPGFRGLPGEPGLQGRGGIPAPPG SRGEQG------AMGFQGPVGFE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GQPGRPGSPGLPGMPGR----SV SIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDICYYANRNDKSYWLSTTAPL-P--MM-PVAEEEIRPYISRCSVCEAPAVAIAV HSQEASIPRCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGAR GTCHYFANKYSFWLTTI-DQPFQ-SKPSADTLKAGLIRSHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_034792866.1 collagen alpha-2(IV) chain [Pan paniscus] M------------------GRDQRAVAGPA-------------LRRW--LLGTVTVGFLA QSVLAGVK-KFDVPCGGRDCS---GGC--QCYPEKGGRGQPGPVGPQGYNGPPGLQGFPG LQGRKGDKGERGAPGITGPKGDVGARGVSGFPG---ADGIPGHPGQGGPRGRPGYDGCNG TQGDSGPQGPPGSEGFTGPPG-PQGPKGQKGEPYALP--KEERDRYRGEPGEPGLVGFQG PPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLG--FYGVKGEKGDVGQPGPNGIP SDLLHP------------IIAPTGVTFHPDQYKGEKGSEGEPGIRGI------------- ---------SLKGEEGIMGFPGLRGY---PGLSGEKGSPGQKGSRGLDGYQGPDGPRGPK GEAGDPGP------------PGLPA----YSPHPSLAK----------GARGDPGFPGAQ GEPGSQGEPGDPGLPGAPGLSIG------------------DGDQRRGLPGEMGPKGFIG DPGIPAL-YGGPPGPDGK---RGPPGPPGLPGPPGPDG---------------FLFGLKG AKGRAGFPGLPGSPGARGPKGWKGDAG-EC-RCTE---GDEAIKGLPGLP---GPKGFAG INGEPGRKGDKGDPGQHGL---PGFPGLKGVPGNVGAPGPKGAKGDSR---TITTKGERG QPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGD-------------GIKGPPGDPGYPG IPGTKGTPGEMG------PPGLGLPGLKGQRGFPGDAGLP--GPPGFLGPPGPTGTPGQI DC--DTDVKRAVGGDRQEAIQP--GC----VGGPKGLPGLPGPPGPTGAKGLR---GIPG FSGADGGPGPKG--LPGDAGREG--FPGPPGFIGPRGSKGAV---GLPGPDGSPGPIGLP GPDGPPGERGLPGEVLGAQ-PGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLK GQPGLPGPSGQPGLYGPPGLH--GFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPG P------VGMKGLSGDRGDAGFTGERGHP--------GSPGFKGIDGMPGTPGLKGDRGS PGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPP--VI LPG-MKDIKGEKGDEGPMGLKGYLGAKGIQGMP-GIPGLSGIP--GLPGRPGHIK-GVKG DIGAPGIPGLPGFPGVA---------GPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATG DFGDIG--DTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIG------------FPG ITGVTGVQGPPGL---------KGQTGFPGLTGPPG----SQGEPGRIGLPGGKGDDGWP GAPGLPGFPGLRGIRGLHGLPGT------KGFPGSPGSDI----HGDPGFPGPPGERGDP GEANT--LPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPP---SNISGAPGDKGAP GIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDS------GPQGRPGVF GLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGI-PQKIA- --------VQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPG FRGDEG------PIGHQGPIGQE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GAPGRPGSPGLPGMPGR----SV SIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYASRNDKSYWLSTTAPL-P--MM-PVAEDEIKPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGR GTCHYYANKYSFWLTTIPEQSFQ-GSPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_023108926.1 collagen alpha-2(IV) chain [Felis catus] M------------------DRHQCSVSSPA-------------LRRW-LLLGAVTVGVLA QSVLAGVK-KFDVPCGGRDCS---GGC--QCFPEKGGRGQPGPVGPQGYTGPPGLQGFPG LQGRKGDKGERGSPGITGPKGDVGARGVSGFPG---ADGIPGHPGQGGPRGPPGHDGCNG TRGDVGRQGPVGPGGFAGPPG-PQGPKGQKGEPYALS--SVDRDKYRGEPGEPGLVGFQG PPGRHGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLG--FYGQKGEKGDMGQPGPNGIP SDIHHA------------IIGPMKEMFHPDQYKGEKGSEGEPGRKGI------------- ---------ALKGEEGVMGFSGIRGS---PGFDGEKGSPGQKGSKGLDGYQGPDGPPGLK GEVGDRGP------------PGAPA----YSPHPSLAK----------GVRGDPGFPGAH GEPGSRGEPGDPGPPGPPGTSIG------------------DEDGKRGLPGEMGPKGFIG DPGIPAL-YPGPPGTDGK---PGPRGPPGPPGLPGPDG---------------FLFGLKG AEGNVGYPGPSGFPGARGQKGWKGDAG-DC-KCAE---GDQFIGGLPGPP---GPKGLPG VNGEPGKKGSQGDPGQHGI---PGFPGFKGAPGNVGPPGPKGVKGDSR---AITTKGERG QPGVPGVPGLKGDDGVPGRDGLDGFPGLPGPPGD-------------GITGPPGDIGYPG TPGTKGAPGERG------PPGLGLPGPKGERGFPGDVGPP--GPPGFPGPAGPPGAPGQI DC--DTGVKRPIGDDGQKTVRP--DC----VGGPKGAPGLRGPPGPTGAKGLP---GIPG PSGADGVPGLKG--LPGDPGREG--FPGPPGFVGPRGSKGVV---GLRGPDGHPGPTGLP GPVGPPGDRGLPGEVLGAQ-PGPRGDAGLPGHPGLKGPPGERGPPGFRGSQGMPGMPGLK GQPGFPGPSGQPGLPGPPGLH--GFPGAPGQEGPLGLPGAPGRGGLPGDRGDPGDIGIPG P------VGMKGLSGDRGDPGLLGERGPP--------GGPGFKGMSGIPGVPGPKGSRGS PGMDGFQGMVGLKGRAGLPGNKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPP--II QPG-MKDIKGEKGDEGPMGLKGYLGLKGVPGMP-GIPGLSGIP--GLPGKPGHIK-GVKG DIGVPGVPGLPGFPGVP---------GPPGIIGFPGFTGSRGDKGAPGRAGLYGEVGPTG DFGDIG--DTIDLPGSPGLKGERGIAGAPGLKGFFGEKGTEGEVG------------FPG ITGVPGVQGPPGP---------KGQAGFPGLTGLQG----PQGEPGRAGAPGDKGDYGWP GIPGSPGFPGIRGISGLHGLPGT------KGFPGSPGVDA----HGDPGFPGPAGDRGDP GEANT--RPGPVGAPGQKGERGNPGERGPVGSPGLQGFPGITPP---SNISGSPGDKGAP GIFGPEGYRGPPGPPGPAALPGRKGDEGNPGAPGNPGTKGWGGDP------GPQGRPGVF GLPGEKGPRGEPGLMGNTGATGSVGDPGPKGPKGDRGLPGAPGSVGSPGIVGI-PQKIT- --------VQPGPVGPHGRRGPPGAQGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPG FRGDQG------PMGQQGPIGQE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GEPGRPGTPGLPGMPGR----SV SIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYASRNDKSYWLSTTAPL-P--MM-PVAEDEIKPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGR GTCHYYANKYSFWLTTIPERSFQ-GSPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_027829588.1 collagen alpha-2(IV) chain isoform X1 [Ovis aries] M------------------DRELRAAARPA-------------LRRW-LLLGAVTVGLLA QSVLAGVK-KLDVPCGGRDCS---GGC--QCYPEKGGRGQPGPVGPQGYTGPPGLQGFPG LQGRKGDKGERGAPGITGPKGDVGPRGVSGFPG---ADGIPGHPGQGGPRGPPGYDGCNG TMGDSGYAGPPGPGGFLGPRG-PQGPKGQKGEPYALS--SEDRDKYRGEPGEPGLVGLQG PPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLG--FYGEKGEKGDMGLQGPGGIP PDNGYV------------EKPTPGYELLPEQYKGEKGSQGEPGRIGV------------- ---------SLKGEEGVMGFSGPRGA---PGFDGEKGLPGQKGSRGLDGYQGPDGLPGPK GEMGNPGP------------PGLPA----YSPHPSVAK----------GIRGEPGSPGAP GEPGARGEPGDPGLPGRPGTTIG------------------DEDEKRGLPGEMGPKGFIG ERGFPAL-YPGPPGADGK---PGLRGPPGRPGPPGPDG---------------FLFGLKG ARGSGGFPGSSGFPGARGQKGWKGDAG-DC-RCA-----DQFIRGPPGLP---GPKGFAG ANGQPGSKGSQGDPGPHGL---PGFSGFKGAPGNVGPPGPKGMKGDSR---TITTKGERG QPGVPGVPGLKGTDGIPGPPGLDGFHGLPGPPGD-------------GIKGPRGDAGQPG APGTKGLPGERG------PPGLGLPGLKGERGFPGDAGLP--GPPGFPGPPGLPGAPGQT DC--DSGVKRPIGADGQETIQP--GC----VGGPKGSPGQPGLPGPPGAKGLR---GVPG FSGADGVPGLKG--LPGDPGREG--FPGPPGFMGPRGSKGAV---GPPGLDGLPGASGLP GPVGPPGDRGLPGEVLGAQ-PGPRGDSGLPGRPGLKGPPGERGPPGFRGSQGMPGMPGQK GQPGSPGFSGQPGLPGAPGQH--GFPGAPGREGPLGPPGAPGFEGLPGDRGEPGDTGVPG P------VGRKGGSGDRGDPGQQGERGHP--------GLPGFKGVSGMPGTPGLKGARGS PGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPP--II LPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMP-GIPGLSGIP--GLPGRPGHIK-GVKG DTGVPGVPGSPGFPGVP---------GSPGVMGFQGFTGSRGDKGAPGRAGLFGEVGETG DFGDIG--DTIDLPGSPGLKGERGTTGIPGQKGFLGERGTEGDVG------------FPG ITGLAGVQGPPGF---------QGQKGFPGLTGLQG----PQGDPGRAGAPGIKGDSGWP GNPGLPGLPGLRGISGLHGLPGN------KGFPGSPGADV----HGDPGFPGPAGDKGDP GEANT--LPGPTGAPGQKGERGAPGERGPIGSPGLQGFPGITPP---SNISGSPGDIGAP GIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGIKGWVGDP------GPQGRPGVF GLPGEKGPKGEPGFMGNIGPTGSPGDRGPRGPKGDRGLPGAPGAVGAPGIAGI-PQRIA- --------VERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGVQGKAGPQGRGGVSAVPG FRGDQG------PVGLQGPVGFE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GEPGRPGSPGLPGMPGR----SI SIGYLLVKHSQTEKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDICYYASRNDKSYWLSTTAPL-P--MM-PVAEEDIRPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGAR GTCHYYANKYSFWLTTIPEQNFQ-GTPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_004054779.3 collagen alpha-2(IV) chain [Gorilla gorilla gorilla] M------------------GRDQRALAGPA-------------LRRW-LLLGTVTMGFLA QSVLAGVK-KFDVPCGGRDCS---GGC--QCYPEKGGRGQPGPVGPQGYNGPPGLQGFPG LQGRKGDKGERGAPGITGPKGDVGARGVSGFPG---ADGIPGHPGQGGPRGRPGYDGCNG TQGDSGPQGPPGSEGFTGPPG-PQGPKGQKGEPYALP--KEERDRYRGEPGEPGLVGFQG PPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLG--FYGVKGEKGDVGQPGPNGIP SDTLHP------------IIAPTGVTFHPDQYKGEKGSEGEPGIRGI------------- ---------SLKGEEGIMGFPGLRGY---PGLSGEKGSPGQKGSRGLDGYQGPDGPRGPK GEAGDPGP------------PGLPA----YSPHPSLAK----------GARGDPGFPGAQ GEPGSQGEPGDPGLPGPPGLSIG------------------DGDQRRGLPGEMGPKGFIG DPGIPAL-YGGPPGPDGK---RGPPGPPGLPGPPGPDG---------------FLFGLKG AKGRAGFPGLPGSPGARGPKGWKGDAG-EC-RCTE---GDEAIKGLPGLP---GPKGFAG INGEPGRKGDKGDPGQHGL---PGFPGLKGVPGNVGAPGPKGAKGDSR---AITTKGERG QPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGD-------------GIKGPPGDPGYPG IPGTKGTPGEMG------PPGLGLPGLKGQRGFPGDAGLP--GPPGFLGPPGPAGTPGQI DC--DTDVKKAIGGDRQEAIQP--GC----VGGPKGLPGLPGPPGPTGAKGLR---GIPG FSGADGGPGPKG--LPGDAGREG--FPGPPGFTGPRGSKGAV---GLPGPDGSPGPIGLP GPDGPPGERGLPGEVLGAQ-PGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLK GQPGLPGPSGQPGLYGPPGLH--GFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPG P------VGMKGLSGDRGDAGFTGERGHP--------GSPGFKGIDGMPGTPGLKGDRGS PGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPP--VI LPG-MKDIKGEKGDEGPMGLKGYLGAKGIQGMP-GIPGLSGIP--GLPGRPGHIK-GVKG DIGAPGIPGLPGFPGVA---------GPPGITGFPGFIGSRGDKGAPGRAGLYGEIGTTG DFGDIG--DTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIG------------FPG ITGVTGVQGPPGL---------KGQTGFPGLTGPPG----SQGEPGRIGLPGGKGDDGWP GAPGLPGFPGLRGIRGLHGLPGT------KGFPGSPGSDI----HGDPGFPGPLGERGDP GEANT--LPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPP---SNISGAPGDKGAP GIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDS------GPQGRPGVF GLPGEKGPRGEQGFMGNTGPTGAVGERGPKGPKGDPGFPGAPGTVGAPGIAGI-PQKIA- --------VQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVTAVPG FRGDEG------PIGHQGPIGQE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GAPGRPGSPGLPGMPGR----SV SIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYASRNDKSYWLSTTAPL-P--MM-PVAEDEIKPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGR GTCHYYANKYSFWLTTIPEQSFQ-GSPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_011488241.1 collagen alpha-2(IV) chain isoform X1 [Oryzias latipes] M-------------------------RHCG------------QRNLW-LPLLCVYIVILT SGVQAGGK-KHSGPCGGRDCS---GGC--KCFPEKGGRGQPGPLGPQGPQGPKGRPGDLG IQGQKGQKGDQGPGGVIGPKGSAGMTGVPGFTG---NDGIPGHPGQGGPRGKPGADGCNG TKGEPGIPGIPGDYGIQGAAG-SPGRKGEKGDNLDVK---VYMQRFRGDQGAPGFDGPFG PDGPKGGEGTRGPTGPKG---PPGPSGPPGPKGTMTKV--LKGVKGEQGDVGQPGPPGND TRQQ------------------------IKPPSGPPGEKGQ---KGQVGEV--------- --------DIITGEPGIPGPPGPRGE---MGRNGQPGLEGEFGERGP---TGIDGVKGVR GEPGVLIL------------SGD---------PWSSGV-------------GAPGPPGEQ GPLGERGPVGDQGIPGRPGPPAYKT------------QQEVYTFGPLGFKGEQGDKGRQG EPGFPAF-RAGPPGADGR---PGDRGPPGPTI--------------------------TW AEYYKGPPGPRGRPGTAGLKGPKGDHG-DC-ECRD----LNARRGLPGPS---GQHGDPG MIGEFGREGDFGDPGPRGV---DGFPGS---PGLPGPLGIKGRKGDIT---FATEKGFPG DSGDPGMDGFPGQLGTPGLHGRPGPPGFPGPPGE-------------GPWGEPGDKGFPG RSGRPGVRGISG------EPGQVFPGQKGLQGLPGDDGLP--GYDGVPGPPGTPG----- GC-------SPTS-GGLGDVTG--LC--DTLPGLPGAPGLPGSPGLPGFPGTQ---GLKG PQGFDGVGGEKG--EQGDRGNGG--SPGPAGFVGQRGDIGIP---GAKGLVGSPGVPGAH GRYGPKGEKGVHGEILGAS-AGPQGDPGLPGLQGLKGQDGEPGLPGYEGMGGMPGMIGFK GEKGSLGLSGEEGKPGIAGLY--GFPGEPGTAGPPGPSGATGDPGLPGERGTDGDPGPPG P------VGLKGMPGEFGEDGSPGEPGSP--------GDPGWPGTTGRPGPPGIKGGKGS SGMVGFDGKKGTPGLKGIIGVKGDAGLPGEQGLKGTMGVPGEKGDRGVKGPPGEKP--QI PLHIIVDMKGVKGEHGSQGNPGFTGPRGSKGLP-GVPGFDGVH--GSPGDPSNDK-GQLG DPGLQGLPGIKGMPGPT---------GNRGVTGFEGMSGEKGIKGSAGAYGASGENGRKG AKGDAG--PRIDLPGSPGLRGEVGLPGNPGLKGLFGSPGDQGGSG------------FDG IVGIKGIFGDPGI---------QGFPGSDGQKGAPG----YQGQKGFSGLPGKDGLPGFP GFPGVKGYPGLKGLHGLHGLKGQ------KGISGTAGLNF----PGQAGNPGVKGQKGES GNPND--QQGDSGIPGFKGFQGPTGEYGLPGLPGLRGPSGPDGI---PNEPGSPGDPGFQ GPAGFQGLPGARGVPGSDASPGQRGEPGLNGFPGFPGNQGFRGDP------GPTGFRGPH GIFGKKGVKGEQGLMGIPGTTGPKGERGQTGFKGNTGLPGFPGQPGSQGPPPI-PIRVP- --------GERGPSGPRGLQGPLGIRGEPGPQGPPGDTGFIGPIGQKGMPGVSGTPGTPG FRGNFG------QMGHPGLEGME------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GNRGNPGIPGIPGMPGR----SI SVGYLLVKHSQSEEKPMCPVGMSKLWDGYSLLYFEGQEKAHNQDLGLAGSCLPRFSTMPF LYCNPGDICYYASRNDKSYWLSTTAPL-P--MM-PVEENEIKPYISRCSVCEAPSVAIAI HSQGIDIPQCPAGWRSLWIGYSFLMHTAAGNEGGGQSLSSPGSCLEDFRTLPFIECNGAK GTCHYFANKHSFWLTSI-DHSFH-ANPAPETLKAGQLRSRISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_021152299.1 collagen alpha-2(IV) chain [Columba livia] M------------------DISQLPSARIF------------VCQDLGLLLILMEVVLSA VKVDAGGK-TYTGPCGGRDCS---GGC--QCFPEKGSRGQPGLLGSQGFTGPPGLMGIPG LQGPKGHKGERGHPGIAGPKGEVGQRGVTGLSYLIFEKSPTGHPGQPGSRGKPGHDGCNG TAGDPGDPGTPGVFGFPGTIG-VQGPKGQKGEPYILP--PDIASRYRGDPGEPGFNGFQG PPGTLGIQGPVGPRGERGRPGPPGPPGPPGPQGNRGLG--FYGEKGEQGPPGPPGPPGLP TRELMG--------------------VPSDKHKGERGEPGQKGEAGTPGEV--------- ------LY-AEKGEEGVMGFPGQRGL---PGINGFPGLSGERGFPGFDGPPGAYGPRGSK GEPGEIGP------------PGPVS----YFPSGFPRK----------GARGDPGVPGVS GLQGDPGEEGDRGLPGLPGFSDA-------------------DGDKPGLPGEMGPKGEKG EIGSPAY-QAGPPGFPGKHGTPGLRGLPGPAGPPG------------------ALFGLKG QEGTPGRFGAQGFPGPRGQKGPKGEEG-DCSHCLL---TEEQRRGSTGSP---GPPGFPG TPGQPGRKGEPGDQGPHGL---PGYPGAKGFPGPHGFPGPKGEKGDSL---YITTKGTKG IRGDPGLPGIRGEDGFPGRDGLDGLPGQPGLPGD-------------VIRGFPGDPGYPG ELGPKGFPGEPG------LQGEGLPGPKGYRGPPGDHGQD--GSPGPPGLPGLPGEPGQL DC--GQVFEDFSRGDATEPIWSGAGC----VRPPKGSQGKPGLPGATGEKGAR---GFPG DPGPVGYPGLNG--TRGDPGREG--LPGPPGFTGPRGDRGPN---GLPGLQGHPGLTGKP GAQGVPGLKGLPGDVLGAP-AGSRGDAGLPGFPGLKGLPGDQGVPGIRGADGNPGLPGAK GEPGPQGLPGLMGLPGIPGTR--GFPGPPGNPGPDGGPGPQGPVGPPGARGEDGEQGVPG P------IGLKGLAGDKGDMGYPGLQGRP--------GVPGPRGVSGMDGFPGDKGSRGS PGIEGFKGMTGLKGRPGIKGIKGEFGPLGAQGDKGAQGARGFKGDRGDQGPPGEPP--KL KPSMMMEVKGEKGDVGERGTKGFFGLKGSKGMP-GLPGKTGIP--GSPGHPSYVA-GAKG DVGAKGLAGLKGYPGPA---------GSPGIRGFPGSTGGRGEKGLPGISGQFGTPGVHG EIGEQE-----EIXXXXXLKGEVGVPGLTGARGGTGQKGEGGDPG------------LPG IEGLKGTQGIPGS---------VGQEGLPGLVGAPG----QQGSPGTPGFQGEKGTPGWP GLPGQPGLPGLRGISGLHGLPGT------KGLPGSPGPDG----YGSAGFPGAVGDKGDA GEPSR--VEGSRGPPGQKGDRGVPA-----------------GI---SNISGYPGDKGSP GLDGVPGYPGLQGQPGIPAPPGSKGESGQPGVSGQTGPKGSRGDP------GPVGTPGVR GYPGPKGRKGEQGVIGFMGTVGFPGDLGPIGPKGDRGVTGFQGPPGSPGLPPL-PPRLV- --------AEQGSPGPRGNMGPQGSPGDMGPQGPPGDPGFRGSPGEPGLQGRGGIPAPPG SRGEQG------ATGFQGPVGFE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GQPGRPGSPGLPGMPGR----SV NMGYLLVKHSQSEQEPMCPTGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDICYYASRNDKSYWLSTTAPL-P--MM-PVAEEDIRPYISRCSVCEAPAVAIAV HSQEASIPHCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGAR GTCHYYANKYSFWLTTI-DQPFQ-SKPSADTLKAGLIRSHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_017911852.1 PREDICTED: collagen alpha-2(IV) chain [Capra hircus] M------------------DRELRAAARPA-------------LRRW-LLLGAVTVGLLA QSVLAGVK-KLDVPCGGRDCS---GGC--QCYPEKGGRGQPGPVGPQGYTGPPGLQGFPG LQGRKGDKGERGAPGITGPKGDVGPRGVSGFPG---ADGIPGHPGQGGPRGPPGYDGCNG TMGDSGYAGPPGPGGFLGPRG-PQGPKGQKGEPYALS--SEDRDKYRGEPGEPGLVGLQG PPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLG--FYGEKGEKGDMGLQGPGGIP PDNGYV------------EKPTPGYELLPEQYKGEKGSEGEPGRMGV------------- ---------SLKGEEGVMGFSGPRGA---PGFDGEKGLLGQKGSRGLDGYQGPDGLPGPK GEMGDPGP------------PGLPA----YSPHPSVAK----------GVRGEPGSPGAP GEPGARGEPGDPGLPGQPGTTIG------------------DEDEKRGLPGEMGPKGFTG ERGFPAL-YPGPPGADGK---PGLRGPPGRPGPPGPDG---------------FLFGLKG ATGSGGFPGSSGFPGARGQKGWKGDAG-DC-KCA-----DQFIRGPPGLP---GPKGFAG ANGQPGSKGSQGDPGPHGL---PGFSGFKGAPGNVGPPGPKGMKGDSR---TITTKGERG QPGVPGVPGLKGTDGIPGPPGLDGFHGLPGPPGD-------------GIKGPRGDAGQPG APGTKGLPGERG------PPGLGLPGPKGERGFPGDAGLP--GPPGFPGPPGLPGAPGQT DC--DSGVKRPIGADGQETIQP--GC----VGGPKGSPGQPGLPGPPGAKGLR---GVPG FSGADGVPGLKG--LPGDPGREG--FPGPPGFMGPRGSKGAV---GPPGLDGLPGASGLP GPAGPPGDRGLPGEVLGAQ-PGPRGDSGLPGRPGLKGPPGERGPPGFRGSQGMPGMPGQK GQPGSPGFSGQPGLPGAPGQH--GFPGAPGREGPLGPPGAPGFEGLPGDRGEPGDTGVPG P------VGRKGGSGDRGDPGQQGERGHP--------GLPGFKGVSGMPGTPGLKGARGS PGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPP--II LPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMP-GIPGLSGIP--GLPGRPGHIK-GVKG DTGVPGVPGSPGFPGVP---------GSPGVMGFQGFTGSRGDKGAPGRAGLFGEVGETG DFGDIG--DTIDLPGSPGLKGERGTTGIPGQKGFLGERGTEGDVG------------FPG ITGLAGVQGPPGF---------QGQKGFPGLTGLQG----PQGDPGRAGAPGIKGDSGWP GNPGLPGLPGLRGISGLHGLPGN------KGFPGSPGADV----HGDPGFPGPAGDKGDP GEANT--LPGPTGAPGQKGERGAPGERGPIGSPGLQGFPGITPP---SNISGSPGDIGAP GIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGIKGWVGDP------GPQGRPGVF GLPGEKGPKGEPGFMGNIGPTGSPGDRGPRGPKGDRGLPGAPGAVGAPGITGI-PQRIA- --------VERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGVSAVPG FRGDQG------PVGLQGPVGFE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GEPGRPGSPGLPGMPGR----SI SIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDICYYASRNDKSYWLSTTAPL-P--MM-PVAEEDIRPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGAR GTCHYYANKYSFWLTTIPEQSFQ-GAPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_006017292.1 collagen alpha-2(IV) chain [Alligator sinensis] --------------------------------------------MTVQVLLLLMLTTLLT GRVQAGGK-TYTGPCAGRDCS---GGC--QCFPEKGSRGQPGPLGPQGFPGPPGLIGIPG LEGPKGHKGERGQPGITGPKGDQGLRGVTGFPG---ADGVPGHPGQPGSRGKPGHDGCNG TTGDPGEQGIHGPPGQFGFIG-AQGPKGQKGEPYVFP--PEIADKYRGEMGEPGIKGFQG PQGEPGLVGFIGPKGRPGKPGLPGLPGPRGEKGNRGLG--FYGVNGEKGERGSEGPPGLP STGEF----------------TTSTDFSIDHCKGQQGMKGEKGEPGISGSR--------- ------ASRAEKGEEGIMGFPGQRGL---PGINGIPGPVGEAGPPGFYGSPGYDGPKGMK GEQGEKGI------------PGLPA----YVPYPIPRK----------GVRGDQGVTGFP GPRGDLGEKGNPGIPGRPGTSDG-----------------LDGLDKRGLPGEMGPKGYKG EPGFSAP-YPGIPGFPGQ---PGPKGFPGSAGPKGSSS---------------ISFGLKG CRGDPGAAGSRGFPGPRGDKGFKGETG-DC-KCTG---SDEARKSSAGLP---GPPGFQG PPGEPGRKGEPGDQGQHGI---PGFPGAKGFPGETGYPGPRGQKGYSV---YITTKGSKG DPGDPGLAGVQGDDGLSGRDGTDGFPGPTGLPGD-------------GTRGLPGDPGFPG PPGVKGFPGDAG------LPGVGLPGPKGFHGLPGDHGTY--GKSGPPGPPGPPGDPAQL DC--DQVPEDLSRGNGRGPIRPGAGC----VRAPAGQPGKPGLPGSTGSKGAK---GIPG DPGLDGLQGLKG--FPGDPGQEG--LPGPPGFHGPRGERGPS---GLLGQQGDDGISGKP GLPGPDGPKGVAGEVLGAS-AGSIGDVGLPGLPGLKGPPGNQGVPGLQGAGGIPGSPGSK GEPGLQGPHGLIGLPGEPGSH--GFPGIPGHQGPAGRGGITGHIGSPGARGDHGEQGFPG P------VGMKGLSGDKGELGIPGVQGIP--------GKTGLPGIDGMHGLQGYKGAKGS PGIEGFKGMTGNRGFQGHKGVKGEIGFFGISGLKGEQGNPGSKGDRGEQGEPGKPP--KI DSGMLVEVKGEKGDSGQTGLKGDSGFKGLKGMP-GLPGEPGFP--GFPGQPSHVT-GAKG DIGSKGVTGSLGYPGQP---------GSPGIRGFPGSTGIRGEKGTEGFTGLYGESGLPG ESGAPG--DTINLPGIPGLKGEVGTPGSSGVRGSPGEKGQRGDPG------------FSG IEGLKGSQGLPGI---------KGQSGFPGLVGPPG----QQGDPGAPGLPGEKGTQGWP GFAGPTGLPGLRGISGLDGLPGT------KGLQGSPGLDD----YGPSGFPGGPGDKGQV GDPST--LEGARGGPGQKGERGNQGERGPTGSPGLDGIPGPPGV---SNISGIRGDVGSP GLYGVPGYKGEQGRRGIPSPPGSKGEIGQIGVVGEDGPKGTRGDP------GLTGKPGIL GSFGAKGQKGEQGVMGPVGTVGISGDTGPTGPKGNRGVTGIQGPPGSPGLTPL-PSKTL- --------AEVGLPGPHGQRGPQGIPGEIGPQGPLGDSGFRGAPGKQGLQGRSGIPALPG FRGDQG------PQGHQGPSGSE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GIPGRPGSPGLPGMPGR----SV NIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYANRNDKSYWLSTTAPL-P--MM-PVAEEEIRPYISRCSVCEAPAVAIAV HSQDVSIPHCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGAR GTCHYYANKYSFWLTTI-EEQFQ-STPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_015821737.1 PREDICTED: collagen alpha-2(IV) chain isoform X1 [Nothobranchius furzeri] M----------------------QTQRSRG------------QRNQR-LLLLCLSLTILY PGVDAGGK-KHSGPCGGRDCS---GGC--QCFPEKGARGLPGPLGPQGFVGPVGRPGDPG IQGPKGQKGDQGIGGIVGPKGSMGMTGVPGFDG---LDGIPGHPGQAGPRGRPGADGCNG THGESGLPGLPGFIGPPGTLG-QQGRKGEKGDTLDIK---VFMQRFRGDPGTPGSSGIFG PMGERGWEGNRGPIGPKG---PPGPPGPPGPKGTMTKY--LKGVKGEPGDIGPQGPPGNY TTQQ------------------------RQPIPGQPGLKGD---KGEIGAL--------- --------ADNKGETGMMGNAGLRGD---SGRDGLTGLRGDPGEPGP---TGRDGTKGVR GDPGELIS------------SG----------SWFTPD-------------GPPGPPGET GPQGERGPIGDQGFPGPPGPPASDSQ----------QQQVWDFFGPFGFTGDKGDKGQRG ERGWPAV-FAGPPGIDGR---VGPIGPPGPKA--------------------------SL EVLFAGDPGWRGQPGRGGLKGQKGDHG-QC-ECKL----GNFQRGLPGPA---GDPGDAG IIGEFGREGDLGDTGPRGQ---DGLPGS---PGTNGLQGPKGRKGNTT---VATQKGLPG DPGEAGKDGPAGVPGSPGPDGLSGFPGNRGLPGE-------------GPRGQHGDKGYPG RPGAPGAAGLRG------VPGQDVTGIKGQRGLPGDDGIS--GYVGVPGTPGAPG----- GC-------SPTGEGGQVDVTG--PC--QPVPGPPGLPGVPGVSGPPGAQGLP---GLKG AVGVAGAKGEKG--EQGEQGTGG--SSGPPGFPGPRGDHGVP---GRKGSIGVPGFPGHS GRYGVQGEKGSHGEVLGAS-PGSQGDPGLPGDQGEKGPIGNPGNPGYSGMGGMPGMIGFK GEKGSPGLIGEEGRPGPAGTH--GFPGDPGRVGLPGPFGETGQPGITGDRGTQGDPGPPG P------TGLKGTPGEHGDFGATGEPGLP--------GDPGQPGGSGRPGHPGLKGSKGS HGMSGFEGMMGNPGQKGLGGLKGEAGVSGEVGLKGLLGKQGAKGERGLTGPRG-----AI AVQMLVNVKGAKGDHGHQGMPGFTGPRGSKGVY-GVPGFPGSD--GLPGEPSKEK-GQRG DPGAQGLPGFKGMPGIT---------GNRGITGFEGMSGNKGIKGSPGAYGALGEDGRKG AKGDKG--LRIDLPGNPGLRGEDGFAGEPGLKGLSGPTGDMGPTG------------FDG IEGIKGTVGDPGL---------AGIPGSDGQKGTPG----NQGQKGFPGIPGKEGQPGFP GFSGIKGYPGLKGLYGLHGLKGH------KGDQGTPGLEG----FGRPGEPGHKGQKGEG GVHND--QPGFPGAVGSKGYQGPQGDIGHPGQPGLPGLAGPDGT---PDIPGQRGDPGFS GPTGHQGVPGSRGLPGLDALPGERGVQGEPGAPGFPGTKGFRGDP------GQSGYKGPH GVSGRKGVKGDQGVMGVPGQIGTKGDRGPSGPKGNTGIPGFPGPTGNRGPAPL-PVITP- --------GERGPPGVQGIMGPKGNRGEPGPQGPPGDSGFMGPIGERGMPGISGTPGVPG FRGEPG------HMGHFGLQGKE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GYRGNPGIPGFPGMPGR----SV SVGYLLVKHSQSDQTPMCPVGMSKLWDGYSLLYFEGQEKAHNQDLGLAGSCLPRFSTMPF LYCNPGDLCYYASRNDKSFWLSTTASL-P--MM-PVEESEIKPYISRCSVCEAPSVAIAV HSQDITIPQCPAGWRSLWIGYSFLMHTAAGNEGGGQSLSSPGSCLEDFRTAPFIECNGAK GTCHYFANKYSFWLTTT-EQEFH-SQPASQTLKAGQLLSHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_020769119.1 collagen alpha-2(IV) chain [Odocoileus virginianus texanus] M------------------DRELRAAARPA-------------LRRW-LLLGAVTVGLLA QSVLAGVK-KLDVPCGGRDCS---GGC--QCYPEKGGRGQPGPVGPQGYTGPPGLQGFPG LQGRKGDKGERGAPGTTGPKGDVGPRGVSGYPG---ANGIPGHPGQGGPRGPPGYDGCNG TMGDAGSAGPQGPGGFLGPPG-PQGPKGQKGEPYALP--RQERDKYRGAPGEPGLVGMQG PPGRPGPIGQMGPVGAPGRPGPPGPPGPKGQPGNRGLG--FYGEKGEKGEMGLQGPGGIP PDNGYV------------EKPTPLYELLPEQYKGEKGSGGEPGRIGI------------- ---------SLKGEEGIMGFSGSRGA---PGFDGEKGSPGQKGSRGLDGYQGSDGLPGPK GETGDPGP------------PGLPA----YSPHPSVAK----------GVRGEPGSPGQP GEPGARGEPGDPGLPGRPGTSIG------------------DEDEKRGLPGEMGPKGFTG ERGFSAV-YPGPPGADGK---PGLRGPPGRPGPPGPDG---------------FLFGLKG ARGGGGFPGSAGFPGARGQKGWKGDAG-DC-KCA-----DQFIRGPPGLP---GPKGFAG INGQPGSKGSQGDPGQHGL---PGFPGFKGAPGNVGPPGPKGMKGDSR---TITTKGERG QPGVPGVPGLKGGDGIPGPPGLDGFHGLPGPPGD-------------GIKGPPGDAGQPG APGTKGLPGERG------PAGLGLPGPKGERGFPGDAGLP--GPPGFRGPPGLPGAPGQI DC--DSGVKRPIGADGQETIQP--GC----VGGPKGSPGQPGLPGPPGAKGLR---GVPG FSGADGAPGLKG--LPGDPGREG--FPGPPGFMGPRGSKGAM---GPPGLDGLPGTSGLP GPVGPPGDRGLPGEVLGAQ-PGPRGDSGLPGRPGLRGPPGERGPPGFRGSQGMPGMPGPK GQPGPLGLSGQPGLPGPPGLH--GFPGAPGREGPLGPPGAPGFEGLPGDRGEPGDTGVPG P------VGMKGESGDRGDPGQQGARGHP--------GSPGFKGVSGMPGAPGLKGARGS PGMDGFEGMLGLKGRPGIPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPP--II QPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMP-GIPGLSGIP--GLPGRPGHVK-GVKG DTGIPGVPGSPGFPGVP---------GSPGIMGFQGFTGSRGDKGAPGRAGLFGEVGPTG DFGDIG--DTIDLPGSPGLKGERGTTGAPGLKGFFGEKGAEGDIG------------FPG ITGLAGVQGPPGF---------KGQTGFPGLTGLQG----PQGDPGRAGAPGTKGDSGWP GNPGLPGLPGLRGIGGLHGLPGS------KGFPGSPGADI----HGDLGSPGPAGDRGDP GEANT--LPGPTGAPGQKGERGVPGERGPIGSPGLQGFPGITPP---SNISGSPGDVGAP GIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGTKGWVGDP------GPQGRPGVF GLPGEKGPRGEPGFMGNIGPTGSVGDRGPKGPKGDRGLPGDPGPVGAPGIAGI-PQRIA- --------VERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGMSANPG FRGDQG------PVGLQGPVGFE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GEPGRPGSPGLPGMPGR----SI SIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDICYYASRNDKSYWLSTTAPL-P--MM-PVAEEDIRPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGAR GTCHYYTNKYSFWLTTIPEQTFQ-GTPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_030285421.1 collagen alpha-2(IV) chain isoform X1 [Sparus aurata] M------------------SGTMRGQHDTG------------LSSLRLLLLLCVSIAILA SGVHGGGK-KHSGPCGGRDCS---GGC--QCFPEKGARGQPGPLGPQGHQGPQGRAGDPG IEGPKGQKGDHGRGGIVGPKGNVGMTGVPGFSG---NDGIPGHPGQAGPRGKPGADGCNG TQGDSGFPGQTGYNGSPGSPG-QPGRKGAKGDSLELS---VYMERFRGDPGTPGVNGIFG PPGHPGWQGNRGIPGPKG---PTGPPGPRGPKGTMTKV--LKGLKGEQGDIGPPGPQGNS THQH------------------------TLPPYGPSGPRGEKGLKGEIGDR--------- --------ADNKGETGIMGFPGHRGE---SGLDGSPGLRGDPGYPGP---KGRDGIKGVR GDAGLLIS------------SGP-------SWPWSSTA-------------GPPGPPGEQ GPVGERGPVGDQGTPGPPGRPASDN------------YQVWQLFGPFGFKGEAGEKGQQG EPGRPAV-SAGPPGTSGR---PGGRGPQGPKG--------------------------TW AEYFKGAPGGRGRPGNAGYKGVKGDHG-EC-ECSV----VNSPAGQPGPA---GEPGDAG MIGEFGQEGDVGDPGPRGE---DGFPGH---AGLSGVPGPKGQKGAET---SATQKGYSG DPGVPGPNGGLGVPGAPGRDGLPGFPGSRGLPGE-------------APSRLRGDKGFPG LPGRPGVAGEAG------EPGEGLKGIKGQRGLPGDDGIT--GYEGVPGTPGSPG----- GC-------SPRGDGEQVDVTG--PC--DPIPGPPGLPGAPGPTGLPGFPGSR---GEKG VQGPLGVTGEKG--ESGEQGIGG--RPGPPGFAGPRGDLGNP---GRKGSLGVPGFPGVS GRHGSQGEKGVHGEILGAS-SGSPGDPGPPGFRGNKGQSGEPGEPGYPGMPGMPGMIGFK GEKGPAGLQGEEGRPGPAGRY--GYPGDPGRAGPPGPPGATGQPGLTGERGTEGDPGPPG P------IGLKGVPGTYGADGATGEYGLS--------GDPGLPGADGRPGLPGMKGYKGS TGMEGFEGMRGDVGVKGFSGSRGEPGVFGEVGPKGVTGHQGLKGDRGLRGPPGDKP--HI PAQIIVDMKGAKGDHGNEGTKGFIGPRGSKGLP-GVPGSEGYH--GLPGDPNNEK-GVQG DPGPQGLPGLKGMPGLT---------GNKGISGFGGMPGKTGIKGSPGAYGASGEKGRKG IKGERG--PRIDLPGVPGLRGELGFSGDPGQKGLFGNPGDRGTLG------------FDG IEGRKGVSGEPGI---------PGNTGTDGQKGSPG----SQGPKGFPGEPGKQGLPGFP GFRGEKGFPGLKGLYGLDGLKGQ------KGFQGKPGLDI----TGPAGESGAKGEKGEG GDPNN--QPGDPGTAGLKGFQGSPGDHGQTGPPGLRGPRGPDGK---PDKPGSRGDPGFV GAKGYEGFPGARGYPGVDAPPGEKGITGGSGFPGFPGIKGDKGDQ------GAPGYKGQH GVSGKKGVKGEQGFMGFPGVTGAKGERGPAGPKGSTGPPGFRGFPGNQGPLPI-PIKVP- --------GERGPPGPRGIQGPQGVRGGIGPHGPPGDGGFMGPVGQKGMPGISGRPGVPG FRGGVG------PMGHPGLQGRE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GLRGNTGVPGLPGMPGR----SV SVGYLLVKHSQTEQTPMCPVGMSKLWDGYSLLYLEGQEKAHNQDLGLAGSCLPRFSTMPF LYCNPGDLCYYASRNDKSYWLSTTAPL-P--MM-PVEEGEIKPYISRCSVCEAPSVAIAI HSQDITIPQCPVGWRSLWIGYSFLMHTAAGNEGGGQSLSSPGSCLEDFRTTPFIECNGAK GTCHYFANKHSFWLTSI-DQSFH-TEPSSETLKAGQLLSRISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_040192142.1 collagen alpha-2(IV) chain [Rana temporaria] M------------------ETSENRKRCLRFHP-----SWKQNVLPW-VLLLIALVMGFP GSVDAGGK-SYTGPCGGRDCS---QGC--QCFPEKGSRGQPGQLGGQGPQGPQGIIGIAG LQGRKGDKGERGHPGISGPTGDKGQSGVTGFSG---ANGVPGHVGQGGSRGKPGHDGCNG TKGDAGEAGFQGIRGPLGPLG-NPGIKGHKGDPFYIS--EDMKKRIRGEPGEPGLAGYPG PNGPPGKVGFIGPMGELGLPGPAGPPGSAGPPGSKGIG--FFGQKGEMGDPGKPGPPGVP CQTQGEPGTTGPTGAPCHLEQVKPSDTSIIDYLAEKGEKGERGDYGAPGEG--------- ------VSSGELGEEGIMGFPGTRGP---SGNDGAPGEKGENGLPGLNGNPGIPGFKGLK GEEGERGV------------PGPPT----YATNLKTQK----------GEQGDPGFPGNV GLDGETGEKGSPGLPGLMGLPSP----------------FPGPPGFPGLTGEKGQKGYQG NSGLPAF-QKGRDGEPGE---PGPRGPSGFPGYPG------------------GRIGRKG AKGSPGNDGSDGYPGYAGLKGLKGEQG-DC-KCSA---GDEATKGPAGDP---GPVGFAG LTGEIGSKGEKGDRGGPGL---PGAPGIKGPAGFNGLPGPVGEKGDGV---IATEKGAKG ERGTPGTQGAEGFEGFSGKDGLYGIPGSSGPPGD-------------APKGLLGEPGFAG SPGLEGARGEPG------LPGVGFPGPKGAHGAPGQPGRN--GSPGIPGLQGLPG----- DCFKEPGEDNQVG---QRPVFPGRGCTLTPPPAPAGTRGPPGLPGFNGVRGVK---GHIG QSGADGMHGFKG--VRGDTGPDS--LPGPQGFPGRRGDRGKP---GTSGLPGERGPSGNP GAQGYQGTKGIPGDVLGAP-SGSRGDVGWPGFSGLKGVQGDAGFPGFQGINGRPGTPGLK GISGDPGIPGTPGLPGPSGNG--GFPGMQGKPGKPGTVGHSGLPGSPGSRGDEGEQGNPG Q------AWKKGEAGDEGELGIAGIRGRI--------GDPGFPGLTGMGGHPGVKGVRGS SGMGGFEGMKGEKGRSAFDGPKGQYGNFGLPGERGNPGVSGNKGDRGEEGPPGPEP--KM EESMLEKMKGEKGILGVPGSPGVPGLNGTKGMP-GHPGNPGLS--GSPGMPSFDT-GNKG DAGQSGFLGFPGSQGPV---------GPPGIRGFPGFTGPRGSKGMPGLYGIPGYKGEFG DKGQTG--DSMDLPGERGNKGVIGDHGFPGQRGIHGEKGFSGDAG------------FPG IEGMSGDPGQPGQ---------KGQTGLPGLLGISG----PQGDPGFPGVHGEKGNSGFS GLPGQQGFPGFRGRSGLDGLKGT------KGLQGPAGVDV----FGVSGIKGTPGQKGDQ GEQNT--LAGLPGNTGGIGARGEPGVPGVTGLPGLIGVRGLPGA---SNLSGIPGDIGPA GPPGQPGHPGPQGRPGVSSRPGEKGDPGPFGIQGIVGERGTPGDR------GFQGFTGIP GYLGLKGQKGQQGIIGDFGLPGFSGDTGPKGPKGDRGSTGLQGAPGEPGLPPV-PVRMK- --------VDSGPVGVFGIVGPQGIPGDMGPRGPEGAKGVHGPQGKEGVPGIPGRSAAPG ARGDLG------SMGQRGPEGGR------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GTSGVPGSAGHPGMPGR----SV NIGYLLVKHSQTEQEPMCPVGMAKLWSGYSLLYFEGQEKAHNQDLGLAGSCLQRFNTMPF LYCNPGDVCYYASRNDKSYWLSTTASL-P--MM-PVVEDEIKPYISRCTVCEAPAVAIAF HSQDSSIPFCPDGWRSLWIGYSFLMHTAAGDEGGGQSLSSPGSCLEDFRATPFIECNGAR GTCHYFANKYSFWLTTI-DNNFH-SSPASDTLKAGLIRTRISRCQVCMKYL--------- ------------------------------------------------------------ ---------- >CAE1304334.1 COL4A [Sepia pharaonis] MSEF-PSLQRETTIAEKMTERMKSRHRRAEKTL-----KYCRQMQSKNFQVLTWLILIFL YITNSVAN-AQNSECGQICAS---GNC--RCIGEKGSRGPHGPIGPRGVQGVRGYPGPEG LTGPKGDKGRAGPPGPSGPKGDRGKIGIPGYPG---VPGIPGIPGEPGPRGPAGLDGCNG TQGSSGLPGIPGSPGKTGPPG-FPGNPGRKGDSG------LGLKGLKGEPGRPGI-GLNG PQGPPGKHGISGPVGPIGPKGSKGSKGNQGMKGHKGIS--FRGDPGPRGPRGPPGKPVVP LD-----------------FSKSLEKTELK---GEKGEIGDRGYEGLPGEKG------DQ GPPGMDGQLGMKGEKGVAGIAGPRGK---QGIPGVPGPRGIKGDRGMEGLPGISGLPGLK GEPGRDGP---RGFDGSVGPPGPPGGT-VVGPPGDPGIQGPRGFT---GPAGMKGNPGPV GPRGLKGEIGGPGIPGPPGNQGRDGP--KGERGEQGFEGLPGKDGLLGRPGFPGAKGEPG QKGEPGI---GDPGLDGIPGRPGKDGRPGAKGDTGLKGQTGPPGQTLDGN--PGPTGPKG DKGGRGFKGQDGINGLNGLPGPKGDKGGECNFCRQ---GSKGERGDPGLD---GPPGRSG LSGSSGEKGEPGEPGEDGL---YGPPGERGYPGDSGLPGSSGPKGQKG-------EPVQA PV-IKGEKGNAGLPGIAGLSGNKGASGPPGPTGP------PGLSGPKGEMGFAGLPGADG RPGEAGRPGRPGAKG---VPGYGLSGPKGQPGEPGQPGVSTLGPKGDKGDPGRKG----- ------------------------------EPGDRGFPGAKGLPGLPGPKGFD---GLPG RPGLDGMKG-----ERGQNGLPG--TAGPRGYNGPRGAKGEP---GLAGLPGEAGITGAK GDRGFSGLKGS---------KGQSSNASVPGSPGRKGERGLDGLPGQRGLDGTPGQRGDR GPTGEDGLPGLPGRDGAKGEP--GI-GLPGRPGPQGP---PGLNGIPGSSGLKGEPGSSG LPGLPGKPGLKGKDGLPGQPGLPGLDGEP--------GIMGPVGKPGLPGLPGSKGERGA VGFSGEPGRNGAPGLPGVKGERGDDGLIGLPGRNGLDGLPGMKGASGLPGLSGMKG---- EPGRV-ASKGEKGEPGLSGLPG---ERGLDGTP-GRDGLPGIQ--GEKGEP-----GI-- --GQSGLPGEDGPP------------GLSGLPGQRGPVGPKGDAGPSGFPGMKGEPGYPG KPGLSG---------------------IPGNDGLPGQKGDRGFPG------------QDG LPGLKGEPSTNGL---------PGLPGEKGESGPRG----PPGQRGYAGMKGDRGLDGFP GAKGNSGLPGTSGIPGADGLPGLPGEKGNSGLPGFPGSDGE---IGDKGDRGFPGEKGDE GPLNLAKIKGERGFTGNTGPKGDKGEQGPNGLNGIEGQKGEKGSRSRSEIPGLKGEPGYP GAKGEPGLPGAPGLDGLPGRDGVKGADGRPGPPGNDGLPGEKGLP------GLSGEPGLQ GQPGLDGLKGEPGLPGLPGLSGEKGDSGLSGLPGENGRSGLKGERGDTGRPGE-PGPAVM --------GPKGNKGLPGLTGPPGFPGLKGDTGLPGNPGLPGLAGERGLPGEAGLTGLPG ADGRPG---------LQGKPGLP------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GTPGLMGPPGPRGPAGR----SA AVGFLFARHSQTTEVPVCPDGLTKLWDGYSLLYLEGNERSHHQDLGWAGSCIKRFSTMPF LFCDFNDVCNYASRNDKSYWLSTNAPM-P--MM-PVGQNEIPPYISRCAVCDSSTNVIAV HSQTLNLPDCPQGWEGLWIGYSFAMHTGAGAGGGGQSLSSPGSCLEDFRATPFIECSGHA GTCHYFANKYSFWLTTI-EQSQQFRAPQPQTLKAGSLRTRVSRCQVCMKKI--------- -----------------------------------------------------GGRRHHN RGFTGP---A >ACK77661.1 RE33133p [Drosophila melanogaster] MLPFWKRLLYAAVIAGALVGADAQFWKTAGTAG-----SIQDSVKHYNRNEPKFPIDDSY DIVDSAGV--ARGDLPPKNCTAGYAGCVPKCIAEKGNRGLPGPLGPTGLKGEMGFPGMEG PSGDKGQKGDPGPYGQRGDKGERGSPGLHGQAG---VPGVQGPAGNPGAPGINGKDGCDG QDGIPGLEGLSGMPGPRGYAG-QLGSKGEKGEPAKEN--GDYAKGEKGEPGWRGTAGLAG PQGFPGEKGERGDSGPYGAKGPRGEHGLKGEKGASCYGPMKPGAPGIKGEKGEPA----- ---------------------SSFPIKPTHTVMGPRGDMGQKGEPGLVGRKG------EP GPEGDTGLDGQKGEKGLPGGPGDRGRQGNFGPPGSTGQKGDRGEPGLNGLPGNPGQKGEP GRAGATGK------PGLLGPPGPPGGG--RGTPGPPGPKGPRGYVGAPGPQGLNGVDGLP GPQGYNGQKGGAGLPGRPGNEGPPGK--KGEKGTAGLNGPKGSIGPIGHPGPPGPEGQKG DAGLPGYGIQGSKGDAGI---PGYPGLKGSKGERGFKGNAGAPGDSKLGR--PGTPGAAG APGQKGDAGRPGTPGQKGDMGIKGDVGGKCSSCRA---GPKGDKGTSGLP---GIPGKDG ARGPPGERGYPGERGHDGINGQTGPPGEKGEDGRTGLPGATGEPGKPALCDLSLIEPLKG DKGYPGAPGAKGVQGF---KGAEGLPGIPGPKGEF---------GFKGEKGLSGAPGNDG TPGRAGRDGYPG------IPGQSIKGEPGFHGRDGAKGDK--GSFGRSGEKGEPG----- SC-------------ALDEIK-------MPAKGNKGEPGQTGMPGPQGEDGSP------- --GERGYTGLKG--NTGPQGPPG--VEGPRGLNGPRGEKGNQ---GAVGVPGNPGKDGLR GIPGRNGQPGPRGEPGISR-PGPMGPPGLNGLQGEKGDRGPTGPIGFPGADGSVGYPGDR GDAGLPGVSGRPGIVGEKGDV--GPIGPAGVAGPPGV---PGIDGVRGRDGAKGEPGSPG LVGMPGNKGDRGAPGNDGPKGFAGVTGAP--------GKRGPAGIPGVSGAKGDKGATGL TGNDGPVGGRGPPGAPGLMGIKGDQGLAGAPGQQGLDGMPGEKGNQGFPGLDGPPG---- LPGDA-SEKGQKGEPGPSGLRGDTGPAGTPGWP-GEKGLPGLAVHGRAGPP-----GEKG DQGRSGIDGRDGIN------------GEKGEQGLQGVWGQPDEKGSVGAPGIPGAPGMDG LPGAAGAPGAVGYPGDRGDKGEPGLSGLPGLKGETGPVGLQGFTG------------APG PKGERGIRGQPGLPATVPDI--RGDKGSQGERGYTG----EKGEQGERGLTGPAGVAGAK GDRGLQGPPGASGLNGIPGAKGDIGP---RGEIGYPGVTI----KGEKGLPGRPG----- -------RNGRQGLIGAPGLIGERGLPGLAGEPGLVGLPGP------IGPAGSKGERGIA GSPGQPGQDGFPGAPGLKGDTGPQGFKGERGLNGFEGQKGDKGDR------GLQGPSGLP GLVGQKGDTGYPGLNGNDGPVGAPGERGFTGPKGRDGRDGTPGLPGQKGE----PGMLP- ------PPGPKGEPGQPGRNGPKGEPGRPGERGLIGIQGERGEKGERGLIGETGNVGRPG PKGDRG------EPGERGYEGAI------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GLIGQKGEPGAPAPAAL----DY LTGILITRHSQSETVPACSAGHTELWTGYSLLYVDGNDYAHNQDLGSPGSCVPRFSTLPV LSCGQNNVCNYASRNDKTFWLTTNAAI-P--MM-PVENIEIRQYISRCVVCEAPANVIAV HSQTIEVPDCPNGWEGLWIGYSFLMHTAVGNGGGGQALQSPGSCLEDFRATPFIECNGAK GTCHFYETMTSFWMYNL-ESSQPFERPQQQTIKAGERQSHVSRCQVCMKNS--------- ------------------------------------------------------------ ---------S >XP_038051105.1 collagen alpha-2(IV) chain-like isoform X1 [Patiria miniata] M----------------RLDVFAALGRTLGGQNS-APRTLTSTMWRWGVVAVLLLAFVGS SIAQK-------ADCGA--TC---KAC--NCKGRQGQRGTPGQIGPEGDRGARGILGYQG VQGPKGDIGDPGAAGPRGQKGDRGMTGVPGFPG---LNGYTGLPGPKGPYGNPGVAGCNG PKGEDGIPGIGGY-GPRGPPG-FNGPKGSKGEPAPYT---PAIQGRRGDPGFDGPDGNPG QQGRNGYPGQQGDRGFKGFQGSRGFDGYQGPPGANSPG--YKGPKGEPGAQGPKGRSASP FSNPP----------------------NIKGSPGTKGDRGETGAKGDVGMFGMQGPKGDP GPKGGKGFLGMKGEKGVLGIAGPRGPVGYTGLPGAPGFIGDRGFDGTRGQDGVPGYQGFR GDVGDDGP---IGFKGDAGIPGEIGDG-PVGPPGPDGDPGLQGHP---GARGAVGDPGEE GLPGRLGEIGGPGPVGRPGLSRD------GQQGDRGVGGIPGKQGFQGSPGEQGQKGQPG DKGAPGFPRAGPVGMDGA---FGRVGERGRKGVVGAQGRPGPPGLTPLGEEIVGPIGETG PRGPKGVVGASGPQGPSGGKGFPGRPAGPCPRCPQ---GLKGQPGDIGFPGTDGRFGPDG ERGPTGEKGANGEPGYLGR---QGQPGFPGLRGPRGLKGDTGDRGTPG------------ -RSIP-VRGYKGERGEQGLKGQIGEPGTQGIQSPFDLNQFRNMT-QKGEMGEKGRKGGRG TDGAPGPAGEDG------VDGERLDGPRGPKGVMGEDGRF-----GFLGPKGQKGEP--A ---------------ERVDIE-------EPIPGPRGEPGPQGAKGGRGPAGFQGQIGFPG PFGDMGIRGTKG--GSGFPGVPS--FPGPKGFPGPRGDKGLV---GIQGEIGRQGRQGEP GNPGFPGRDGMRGDRGEDGQSGSVGPTGFPGDEGPQGIKGTNGFNGLPGQSGFPGFQGMN GERGDPGPFGPQGERGLKGATGIGFPGRQGSPGRDGPRGPQGPTGAEGPPGDRGVFGGIG STGD---NGEDGFPGERGQQGERGEKGFPGR-----AGRPGLFGARGEFGDPGLDGLPGN PGQKGNAGFPGFSGRPGEPGPQGLPGKDGLPGLIGETGDPGRTGQVGLFGDFG------- EPGDI----GEPGEDGADGLIG---PLGQDGRP-GSPGFPGPI--GNRGFS-----GITG MVGDKGGVGEQGRPGNLGLD---GLTGEKGYRGLRGFRGVTGFEGDLGLIGRPGPRGPQG PAGQKG---DSGVPGTPGLFGEVGPPGDPGSRGSKGIKGSSFNPNDIK---------EPG -TGEKGAKGEKGD---------QGSRGLNGLRGTVG----DRGPSGEPGNQGYDGYDGFD GIAGMRGDPGLPGLFGVEGLPGM------PGEDGNPGI------KGRQGLPGPQGPKGVI G------FSGFSGFPGSAGTDGRPGERGPRGNKGFPGLPGVPGFPVFIAPAGEPGEDGPR GPDGPKGFVGQPGQPGFPGFSGLKGPKGEPGLTGL-GSPPVLGPP------GAKGIQGPT GVPGLKGRVGDIGFPGPVGELGPFGLKGYPGYPGRQGRPGLPGFNGPKGQ----PGDQP- -------------DAQKGVKGDSGDPGPFGIRGRPGRPGFAGVDGSVGLKGMKGDFGDPG EPGSIGPKGQFGPQGLRGDFGDP------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GPQGFKGGKGVGGEEGSPGPPPR PQGFIVVKHSQSRNIPRCDVGMTQLWTGYSLLYTEGNEKAQHQDLGLAGSCLPRFSTMPY VFCNFNEICNFAQRNDKSYWLATSEAI-P--MM-PVEGNGIRPYISRCAVCETPTQVIAV HSQDTTLPDCPRNWRSLWIGFSFAMYTSAGADGGGSALASPGSCLEDFRATPFIECNG-R GRCFFYRNTYSFWLTTV-DADAMFRPQESQTLKAGSLRSRVSRCQVCQKIL--------- ------------------------------------------------------------ ---------- >NP_001022662.2 Collagen alpha-1(IV) chain [Caenorhabditis elegans] M-------------------------------------------SRLSLLGLTAAVVLLS SFCQDRIHVDAAAACKG--CA---PPC--VCPGTKGERGNPGFGGEPGHPGAPGQDGPEG APGAPGMFGAEGDFGDMGSKGARGDRGLPGSPG---HPGLQGLDGLPGLKGEEGIPGCNG TDGFPGMPGLAGPPGQSGQNG-NPGRPGLSGPPGEGGVNSQGRKGVKGESGRSGVPGLPG NSGYPGLKGAKGDPGPYGLPGFPGVSGLKGRMGVR-----TSGVKGEKGLPGPPGPPGQP GSYPW--------------ASKPIEMEVLQGPVGPAGVKGEKGRDGPVGPPGM---LGLD GPP---GYPGLKGQKGDLGDAGQRGKRGKDGVPGNYGEKGSQGEQGLGGTPGYPGTKGGA GEPGYPGR---PGFEGDCGPEGPLGEG-----TGEAGPHGAQGFDGVQGGKGLPGHDGLP GPVGPRGPVGAPGAPGQPGIDGMPG---YTEKGDRGEDGYPGFAGEPGLPGEPGDCGYPG EDGLPGYDIQGPPGLDGQSGRDGFPGIPGDIGDPGYSGEKGFPGTG-VNK--VGPPGMTG LPGEPGMPGRIGVDGYPGPPGNNGERGEDCGYCPD---GVPGNAGDPGFPGMNGYPGPPG PNGDHGDCGMPGAPGKPGS---AGSDGLSGSPGLPGIPGYPGMKGEAG----EIVGPMEN PAGIPGLKGDHGLPGLPGRPGSDGLPGYPGGPGQ------NGFPGLQGEPGLAGIDGKRG RQGSLGIPGLQG------PPGDSFPGQPGTPGYKGERGAD--GLPGLPGAQGPRGIP--- ---------------APLRIV-------NQVAGQPGVDGMPGLPGDRGADGLP---GLPG PVGPDGYPGTPG--ERGMDGLPG--FPGLHGEPGMRGQQGEVGFNGIDGDCGEPGLDGYP GAPGAPGAPGETGFGF----PGQVGYPGPNGDAGAAGLPGPDGYPGRDGLPGTPGYPGEA GMNGQDGAPGQPGSRGESGLV--GIDGKKGRDGTPGT---RGQDGGPGYSGEAGAPGQNG MDGYPGAPGDQGYPGSPGQDGYPGPSGIP--------GEDGLVGFPGLRGEHGDNGLPGL EGECGEEGSRGLDGVPGYPGEHGTDGLPGLPGADGQPGFVGEAGEPGTPGYRGQPG---- EPGNL----AYPGQPGDVGYPG---PDGPPGLP-GQDGLPGLN--GERGDN-----GD-S YPGNPGLSGQPGDAGYD------GLDGVPGPPGYPGITGMPGLKGESGLPGLPGRQGNDG IPGQPG---LEGECGEDGFPGSPGQPGYPGQQGREGEKGYPGIPGENGLPGLRGQDGQPG LKGENGLDGQPGYPGS------AGQLGTPGDVGYPG----APGENGDNGNQGRDGQPGLR GESGQPGQPGLPGRDGQPGPVGPPGD---DGYPGAPGQDI----YGPPGQAGQDG----- -------YPGLDGLPGAPGLNGEPGSPGQYGMPGLPGGPGE------SGLPGYPGERGLP GLDGKRGHDGLPGAPGVPGVEGVPGLEGDCGEDGYPGAPGAPGSN------GYPGERGLP GVPGQQGRSGDNGYPGAPGQPGIKGPRGDDGFPGRDGLDGLPGRPGREGL----PGPMAM --AVRNPPGQPGENGYPGEKGYPGLPGDNGLSGPPGKAGYPGAPGTDGYPGPPGLSGMPG HGGDQG---------FQGAAGRT------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GNPGLPGTPGYPGSPGGW---AP SRGFTFAKHSQTTAVPQCPPGASQLWEGYSLLYVQGNGRASGQDLGQPGSCLSKFNTMPF MFCNMNSVCHVSSRNDYSFWLSTDEPMTP--MMNPVTGTAIRPYISRCAVCEVPTQIIAV HSQDTSVPQCPQGWSGMWTGYSFVMHTAAGAEGTGQSLQSPGSCLEEFRAVPFIECHG-R GTCNYYATNHGFWLSIV-DQDKQFRKPMSQTLKAGGLKDRVSRCQVCLKNR--------- ------------------------------------------------------------ ---------- >XP_039251035.1 collagen alpha-2(IV) chain-like [Styela clava] M------------------------------------------RKSILFIVIIGIICIQE ATARKRKR-NIKGPCAGRDCRN-LGPC-SFCVSEKGNRGFPGRQGDVGTTGPPGFPGPEG LSGPKGEKGYPGRIGARGQSGSRGETGAPGYAG---VNGLPGHPGEQGPVGHPGLDGCNG TEGDLGPRGEAGPPGLPGPVG-RDGAPGEKGEPAYVD-DASMIKGASGEDGPIGPEGRPG IQGPVGQMGPMGYDGPPGPPGPPGRKGQKGDEGNEGIG--YQGEKGEKGSIGTAG--GRP DFLE---------------RNPPGFTQPLKGLPGRNGSKGYKGEKGDIGFPG------FV GPPGFDGMQGETGEKGVRGPAGPRGP---SGVPGVNGFNGRKGEPGDDGRPGTDGAQGLK GERGVPGSEGIPGFRGLDGLDGPSG------PPGFPGPEGERGIR---GETGIPGLDGQS GLHGEKGERGNRGPAGSPGDSVQ------GEKGRTGLKGLDGLDGVPGPAGLPGDKGSRG DVGAPGRSVKGESGKDGMDGLPGLRGLQGPRGRPGESGKLIYDGENIVGE--TGPTGDVG AKGAKGLKGEMGPTG---LMGMKGDHGGEC-DCADAV-GERGDPGSRGPP---GYPGRNG LPGIPGREGERGPPGENGA---MGTPGDLGPRGFSGIPGPPGRKGEPA--TGDIFKAQKG EQGVPGGQGPPGLDGLPGRAGGIGGPGARGEKGEL------------GPIGKPGKPGPQG SDGERGNPG---------RPGRDVEGTPGARGLKGESGRP--GLPGITGYPGKQGPP--G EA-------------LEVEVP-------RGEKGLMGLPGPPGLPGSKGDTGDM---GRPG VDGLAGVVGESG--EPGPPGLPG--LPGPKGFPGETGDKGGP---GPPGRDGYDGDYGVP GPPGEKGVKGERGVSDIRGRTGGEGPKGNPGKGGGKGPVGEPGTPGEPGKMGADGKPGPD GEPGLIGPAGRLGPPGQKGES--AFEGRPGDRGPTGPRGPPGLIGVTGPKGEIGGAGPPA TGKF---KGMKGFPGLPGKYGEKGFTGPPGQ-----AGEPGRPGFEGFPGPNGMMGVIGS VGLPGPPGKMGQKGSYGPEGPKGDTGREGIPGDVGGRGDVGSKGPKGEKGQPGEALN-VT IVGQLMAS-----------------KHGEPGAP-GERGLPGLP--GMIGMT-----GKKG EEGDPGKKGEPGEAGPS-----TG--GLPGRPGLDGLNGEDGETGEPGLPGLIGESGEKG DVGRPG---PNGLPGPSGETGQ------PGRDGPEGSPGLAGLDG------------LNG MNGDKGTKGRPGLSGI------VGISGMPGTRGIRG----DRGFTGPPGTPGEKGMVGFP GRNGIDGLNGRTGLSGPTGTKGEKGDAGISGLDGLDGTDGTNGPKGRPGFSDVPGPAGSI GLPGLQGPPGESGLPGLSGSQGRQGDRGDVGLPGLGGRQGFPGD---AGLPGFPGEKGEA GLNGRQGLPGPPGPPGPEGEIGLPGNAGERGMRGMNGNPGLPGRDGR---PGSPGESGSP GDIGERGDKGMKGMSGLTGIQGPDGAKGNAGLQGQIGRPGFPGRPGERGDAGP-PGRSL- -------EPENVPPGPKGEKGRRGLPGLMGLEGEPGPSGIEGFKGEPGIPGRNGINGIPG PRGERGSD---GPTGLTGPQGPA------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GLDGARGTKGRTGKPGK----FR PAGHLIVRHSQTVDVPTCPGGTSKLWSGFSMLYLSGSERAHGQDLGSTGSCLRRFNTMPF LYCNVNEVCNYASRNDKSYWLATTLPI-P--MM-PV-ETGLEEYVSRCTVCESQSIAMAF HSQSDMIPDCPNGWKGLWFGYSFVMHTASGADGSGQSLSSPGSCLEDFRATPFIECNGAR GHCFFYNNQFSYWLTTI-SKEEQFTSPKKETLKAGNLRTRVSRCQVCAKVL--------- ------------------------------------------------------------ ---------- >XP_006563187.2 collagen alpha-5(IV) chain [Apis mellifera] M--------------------VPRANATRG--------LRSFPVVLRVTCVLALLVVTWI PVTEA-------VICRD---S---YKC--NCTGIKGGAGYPGIPGLQGPEGPPGDIGPDG PPGPKGEKGAGGEYGGMGEKGYRGEQGIQGFPG---AAGLPGKPGSPGVMGPDGLDGCNG TDGRAGSPGIPGVHGERGPPG-PMGDYGPIGEPGDGGINSVGVKGVRGNPGMNGLEGYPG SYGIPGEMGYPGETGDMGFRGSPGLPGMQGDVGDTVYG--IKGAEGEQGDRGEPGPPSNG E------------------FKEKTKVTPVKGATGPKGMRGDAGERGRKGEMGA---KGPI GRA---GFFGIKGTKGEQGDDGPRGKQGAEGPPGPAGEKGEKGAPGYAGKPGPDGFDGEL GDGGNQGP------PGKQGAPGEPGKYIPELDEIIQGNIGIQGDLGPPGNPGEPGTPGLP GKVGYIGPPGPPGPPGSSGLPGLKG---SSVKGEPGDDGFTGEMGLQGPPGAPGIPGTVG LKGYPGLTIVGPPGPDGKPGYPGVPGLPGDRGDPGVQGPKGFPGKG-SRN--PGPPGERG LPGIPGLPGPDGWPGLPGLKGVKGFKGDDC-NCPPVKPGPKGEQGDSGLD---GYPGTPG YPGLPGPRGFKGVQGKRGI---VGPRGLEGDSGRPGVAGPQGPKGERG----RLIVPDKK IIGTPGDIGDKGYPGIEGPTGPRGEPGFRGDTGP------EGPKGEKGELGPPGRPGGDG YPGINGIPGEKGDDA--STPMEFLKGEPGSPGIPGLRGPP--GDKGAKGERGISS----- ----------------QYNIQ---------LKGEKGYKGERGDPGEDGAKGPE---GWPG DEGFIGPSGIPG--------SPGISRQGPVGLKGYPGMPGDQ---GPRGAPGTPGSEGFV GFPGRVGNKGDRGDPGSNQTYGDYGLMGWTGEKGNVGDAGPMGYRGRPGPDGTKGAKGSK GAPGSAGIPGLQGVKGQRGD------RVQGSKGMPGI---HGQPGMPGRMGEVGIPGPDG TLGFDGMKGLKGEIGFMGRRGDDGDIGPP--------GYLGRDGIPGLPGPPGPDGDVGE IGEPGPRGWLGLEGLSGPMGAKGEQGDVGPVGIPGIVGLPGSKGISGDPGPVGLDG---- LPGEN-AFSGPQGDIGEPGFMG---EVGAPGLP-GMDGRPGLP--GEPGLATDGFNGLRG EKGEAGINGLNGLPGPK---------GEIGDMGLDGLKGARGDWGLKGRPGIPGSPGLHA VKGERG---PIGPPGIEGLKGKRGLDGDPGRMGLPGMPGDQGHRG---------SPGLMG APGPKGYVGEPGLPSYGEVE--GGDFGMPGLNGLPG----EKGERGEQGFVGLPGRKGMK GNIGYRGPDGFPGVPGFPGLPGD------EGPPGFPGI------SGQFAEPGEDG----- -------RPGMDGIPGTPGIPGQKGAPGEYGPNGPIGITGDVGF-SIRGPKGLAGDMGPR GFDGYPGAPGLQGMPSLPGLPGPKGYPGEIGLPGI-SIKGESGER------GLDGFDGRP GT---KGIRGDSGLSGFVGLPGAKGEPGDVGEPGIIGLPGPPGPKGPKGDRGMNP----- -------FSPFPRKGLPGDTGPPGLPGFPGLPGMLGEPGEDGLPGREGEPGMVGLPGLPG PEGEEG------PAGYTGPPGVI------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GRQGLPGSPGISGNPAPPAPGPR NRGFYFARHSQSEMIPLCPPNTIKLWDGFSLLHVRANGKSHGQDLGTAGSCVVKFNTMPF TFCNLNNQCNYADREEFSYWLSTTEPM-PMSMA-PIPAPQVGRYISRCSVCEAPTRAIAV HSQTMAIPQCPGGWEELWIGYSFLMHRDVGNGGGGQSLVSPGSCLEEFRIRLFIECRS-K GTCNYFSTATTFWLTTI-KDYEMFRKPIPQTLKTDH-TSRVSRCVVCLRRRVTEDVKSLK PFISNGQREQVGNIRYSPHSRPVHYPDYQYQKKPPIGRTRGPNRRVPYHYRKKGGRLRKP ERTTEPPEAA >NP_999631.1 3 alpha procollagen precursor [Strongylocentrotus purpuratus] M-------------------------------------KYREVLERHVFVCLSLLIIVFA YWADA-------AACVG-CLS---ATC--ICNGTKGERGDRGYVGFPGPPGPGGFPGVEG PPGYKGQKGNLGIAGSGGPKGFRGSLGNPGIPG---IPGIPGEPGQEGPPGEPGIPGCNG TKGERGPSGPTGF-GQPGSPG-PRGDPGPQGPPGDTT---YGLKGIKGEPGRLGRDGYPG TPGDSGPTGPKGISGDPGLLGSKGTRGLKGEPGQPGVQ--YQGGKGEKGSVGTQGLPGES CRDQ---------------AATGNDTTIVQGRPGPKGDQGEYGDKGDKGFLGM---KGMK GPK---GQYGLKGEKGLSGPQGPRGK---IGKDGTPGNQGMKGSPGIPGNPGPTGFNGQL GDKGDRGP------KGRVGPPGPPGPSVPVNDKGTKGLPGPSGRH---GSAGPRGYPGEK GRTGYDGKAGQPGPPGSAGDRGVPGPVGIGEKGEPGNPGIPGMPGPNGFQGLPGRDGPKG DKGMAGLTIQGLPGMDGRPGPDGPAGLPGQVGDAGPQGLIGEPGNGLPGD--PGPKGQTG RDGPRGIPGDVGSSGQPGLPGPQGSKGEACAACRSGEIGPKGDPGQSGEI---GQPGQPV YNGNSGPSGPKGDRGLRGL---TGRDGQDGPQGPPGSTGRPGNKGQLG---------LQG EVGFT-EPGPRGIQGDPGLKGDNGLNGEPGPPCEPGA---VKVNGEKGALGPPGPPGRDG VPGYQGQKGDRG------LPGDSLRGSNGEKGDQGPRGER--GTYGSPGDKGEVV----- ----------------YYETGT------QGPKGEPGNPGTAGPPGPAGPTGNQ---GLPG DQGPDGYQGEKG--SQGQSGPPGNSIPGSPGEKGAQGIPGDV---GQPGQPGPTGPLGNP GIPGAFGEKGDFGPQGNPGGQGLRGLTGQPGQPGIGGERGNIGDPGTRGRDGIPGQAGGK GETGPGGLPGGPGIKGEPGL------SIPGQDGSSGT----------------------- -------PGRDGAPGGPGEPGPSGPRGEPAQPLLEETRITRLNGQRRPPGQPGDNGAPGN DGEPGPAGQIGVKGSPGPLGPGGSQGPPGSPGPIGAPGEKGERGGMGTPGSPGPSG---- SPG----AKGEPGLPGPLGEKESRGPGGVPGSK-GESGIPGRS--GGIGSP-----GSIG LPGLNGVKGEPGIPGNSGIPGGRGLNGEPGPAGFKGFQGLLGVKGDFGIKGQMGFPGPKG DNAQMG------IPGQNGGEGFPGRSGIPGPQGAPGSPGEPGTDG------------SNG GPGSKGEKGQPGIIRDLLAGWRKGVKGDPGRTGPEG----AKGNPGLPGIPGESGDAGLP GSEGRPGQPGTSGPPGPPGPNGEPGLIGRTGTPGDPGPRGERGSYGTPGEDGIPGVKGDS G------DPGLMGLPGGPGLPGPGGPPGESGFPGVRGVKGIPGT---PGLSAL-GIKGEP GFPGLKGDSGQPGLNGGSGSIGLPGMKGTKGETGPVG-PRSPLPPVI---PGPKGEIGIP GANGDRGDKGDRGEPGRPGFQGRPGESGSPGLNGQMGDPGGPGFQGLKGSKGE-PGPIPN VFEMKGVKGDRGGPGPDGPQGPPGRDGRPGPQGPPGLTGDKGTPGVQGNPGVSGVPGEPG LKGEQG---------FRGQNGQP------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GDPGFPGTKGEAGIPGS------ SSGFFITRHSQTTSIPQCPQGTAKMWHGYSLLFVQGNERGHGQDLGKPGSCLKRFSTMPF LFCNINNVCHVASRNDYSYWLSTTEPM-PMNMA-PIRGGQLQPFISRCVVCEAPAQVLTV HSQTVNIPDCPDRWGVLWIGYSFMMHTGPGGEGSGQMLSSPGSCLEDFRSSPFIECHG-D GKCNYYATTYTFWLSSI-TGNAQFTMPQSETLKAGSLRTRVSRCAVCLRNQ--------- ------------------------------------------------------------ ---------- >XP_031568877.1 collagen alpha-2(IV) chain-like [Actinia tenebrosa] M----------------------------------------------------------- ----------------------------------------------------------EG IMGPRGIKGDKGEFGAEGAKGPRGKVGRPGFPG---QPGIPGIPGNEGARGEHGEPGCNG TQGDRGSDGQPGRPGRIGVKG-NIGPPGPRGFPGEAP---STLKGVKGEPGPFGPVGPQG PRGDVGVPGPKGDIGPPGPLGIPGPPGPTGKKGEMGIR--FEASKGDKGAKGVPGPKGQP NPILP--------------STCGNTTATLKGEKGPPGLRGLPGPRGEKGEPGV---NGPI GER---GFPGQKGNKGEPGNDGPVGKPGKDGDIGLPGPMGXRGFPGDIGLPGEPGPVGPS GAPGAPGP------QGKEGAPGPPG----VGPPGFQGDTGATGTP---GFPGIKGARGPP GPPGNIGPLGPPGPQGFKGDKGP-----LGPPGIIGTPGSPGMKGPPGKPGAQGDPGTPG DRGPRGFTIQGDPGMDGL---------PGPRGETGGKGDRGFPGPPGSST--NGPPGEKG EPGFPGVQGNDG------PSGPQGPKGDQCGPCPTPPAGPKGDKGSVGLP---GENGAVG PPGEIGVPGAPGKPGTTGR---SGRPGPMGPSGDPGIKGKDGAKGDRG----ELIK-IKG EKGTPGTSGPPGPFGPPGIRGRPGADGQKGSPGPT------------GSIGLKGAPGVNG KDGLKGAPGFSGPKGEKGEKGLFVQGRPGXPGPQGERGPL--GPKGLPGPTGEKGTS--W DN-------------TQGQIN-------QGXPGDPGVPGKDGLKGEKGDNGKG---GLPG PPGARGVDGAKGVDGEGQPGPPG--PPGPQGQRGPIGEKGDS---GPPGSQGFTGPDGLP GPRGPTGLKGDDGPPGRPGLPGTPGLRGFDGIKGNPGPPGRDGLPGQPGERGSIGAIGLP GEPGPKGTAGVKGDKGDKGL------SVEGPPGEPGP---PGLRGSPGLKGVRGRDGSNG ANGFPGGPGLNGDIGLPGDPGNSGPPGPP-----------GLPGKDGTDGNIGEKGFPGL PGPRGPSGENGLPGTRGAQGTPGDPGIPGPPGDTGRAGFPGFKGDKGGKGIQGPPG--TT EPGNI------PGPKGMTGNPG---QPGPPGAN-GVDGIRGFK--GDIGLP-----GDIG TPGPPGKSGQPGPP------------GPPGSPGKKGENGRDGINGINGLRGDIGLPGPPG VDGTDGTPGSEGPPGQKGSKGNPGR-GLVGPRGPPGAPGMKGLPG------------FPG IKGSKGVNGADGRPGDIGPVGPKGFKGSSGAKGDQGENTVERGPPGPPGLPGRDGIDGLN GEKGNTGVPGNPGPPGAQGVRGRKGD---KGVSGLPGQ------RGPSGDPGPRG----- -------PQGPRGIAGVPGNPGSPGIPGLPGMPGLKGAKGE------LGLPGTPGSDGTP GAKGDKGNPGFPGVDGRPGEDGPAGEKGDTGLPGTXGAKGATGRPGVEGPSGARGSPGLP GFKGLKGEPGKDGLPGTPGNKGAPGADGFPGLPGXKGNTGIPGLPGLKGEKGY------- ---------GLGTXGPKGDRGDAGLPGINGDKGEPGIPGFPGGPGPKGDKGLMGADGREG PRGNPGFP---GRDGSKGESGPA------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GLPGVPGPTGRRGPQG-----TS DFGFFFTRHSQTDQLPSCPDSTFPLWTGYSLLYVQGNERAHGQDLGSPGSCLRRFSTMPF LFCNIENVCNLASRNDYSFWLSTTAPV-P--MM-PVREENVQRHISRCAVCEARAQVIAV HSQSNALPDCPRDWDPLWQGYSFLMHTSAGNDGSGQPLSSPGSCLEDFRAHPFIECHG-R GTCQYYGSTYSFWLATV-DAKNQFRVPRPETLKAGTLRERVSRCKVCMRRL--------- -----------------PKPKGV----------------------------ATGGRLRN- ---------- >XP_043748401.1 collagen alpha-2(IV) chain [Cervus elaphus] M------------------DRELRAAARPA-------------LRRW-LLLGAVTVGLLA QSVLAGVK-KLDVPCGGRDCS---GGC--QCFPEKGGRGQPGPVGPQGYTGPPGLQGFPG LQGRKGDKGERGAPGTTGPKGDVGPRGVSGYPG---ANGIPGHPGQGGPRGPPGYDGCNG TMGDAGSAGPQGPGGFLGPPG-PQGPKGQKGEPYALP--REERDKYRGEIGEPGLVGMQG PPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLG--FYGEKGEKGDMGLQGPGGIP PDNGYV------------EKPTPLYELLPEQYKGEKGSGGEPGRIGI------------- ---------SLKGEEGIMGFSGSRGA---PGFDGEKGSPGQKGSRGLDGYQGSDGLPGPK GETGDPGP------------PGLPA----YSPYPSVAK----------GVRGEPGSPGQP GEPGARGEPGDPGLPGRPGTSIG------------------DEDEKRGLPGEMGPKGYTG ERGFPAV-YPGPPGTEGK---PGLRGPPGRPGPPGPDG---------------FLFGLKG ARGSGGFPGSAGFPGARGQKGWKGDAG-DC-KCA-----DQFIRGPPGLP---GPKGFAG TNGQPGSKGSQGDPGQHGL---PGFPGFKGAPGNVGPPGPKGMKGDSR---TITTKGERG QPGVPGVPGLKGGDGIPGPPGLDGFHGLPGPPGD-------------GIKGPPGDAGQPG APGTKGLPGERG------PPGLGLPGPKGERGFPGDAGLP--GPPGFRGPPGLPGAPGQI DC--DSGVKRPIGADGQETIQP--GC----VGGPKGSPGQPGLPGPPGAKGLR---GVPG FSGADGVPGLKG--LPGDPGREG--FPGPPGFMGPRGSKGAV---GPPGLDGLPGTSGLP GPVGPPGDRGLPGEVLGAQ-PGPRGDSGLPGRPGLKGPPGERGAPGFRGSQGMPGMPGQK GQPGSPGLSGQPGLPGPPGLH--GFPGAPGREGPLGPLGAPGFEGLPGDRGEPGDTGVPG P------VGMKGESGDRGDPGQQGARGHP--------GSPGFKGVSGMPGAPGLKGARGS PGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPP--II LPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMP-GIPGLSGIP--GLPGRPGHVK-GVKG DIGIPGVPGSPGFPGVP---------GSPGIMGFQGFTGSRGDKGAPGTAGLFGEVGPTG DFGDIG--DTIDLPGSPGLKGERGTTGAPGLKGFFGQKGAEGDVG------------FPG ITGLAGVQGPPGF---------KGQTGFPGLTGLQG----PQGDPGRAGAPGTKGDSGWP GNPGLPGLPGLRGIGGLHGLPGS------KGFPGSPGADL----HGDLGFPGPAGDRGDP GEANT--LPGPTGAPGQKGERGVPGGRGPMGSPGLQGFPGITPP---SNISGSPGDIGAP GIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGTKGWVGDP------GPQGRPGVF GLPGEKGPRGEPGFMGNIGPTGSVGDRGPKGPKGDRGLPGAPGPVGAPGIAGI-PQRIV- --------VERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGMSANPG FRGDQG------PMGLQGPVGFE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GEPGRPGSPGLPGMPGR----SI SIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDICYYASRNDKSYWLSTTAPL-P--MM-PVAEEDIRPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGAR GTCHYYTNKYSFWLTTIPEQTFQ-GTPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_043334259.1 collagen alpha-2(IV) chain [Cervus canadensis] M------------------DRELRAAARPA-------------LRRW-LLLGAVTVGLLA QSVLAGVK-KLDVPCGGRDCS---GGC--QCFPEKGGRGQPGPVGPQGYTGPPGLQGFPG LQGRKGDKGERGAPGTTGPKGDVGPRGVSGYPG---ANGIPGHPGQGGPRGPPGYDGCNG TMGDAGSAGPQGPGGFLGPPG-PQGPKGQKGEPYALP--REERDKYRGEIGEPGLVGMQG PPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLG--FYGEKGEKGDMGLQGPGGIP PDNGYV------------EKPTPLYELLPEQYKGEKGSGGEPGRIGI------------- ---------SLKGEEGIMGFSGSRGA---PGFDGEKGSPGQKGSRGLDGYQGSDGLPGPK GETGDPGP------------PGLPA----YSPYPSVAK----------GVRGEPGSPGQP GEPGARGEPGDPGLPGRPGTSIG------------------DEDEKRGLPGEMGPKGYTG ERGFPAV-YPGPPGTDGK---PGLRGPPGRPGPPGPDG---------------FLFGLKG ARGSGGFPGSAGFPGARGQKGWKGDAG-DC-KCA-----DQFIRGPPGLP---GPKGFAG TNGQPGSKGSQGDPGQHGL---PGFPGFKGAPGNVGPPGPKGMKGDSR---TITTKGERG QPGVPGVPGLKGGDGIPGPPGLDGFHGLPGPPGD-------------GIKGPPGDAGQPG APGTKGLPGERG------PPGLGLPGPKGERGFPGDAGLP--GPPGFRGPPGLPGAPGQI DC--DSGVKRPIGADGQETIQP--GC----VGGPKGSPGQPGLPGPPGAKGLR---GVPG FSGADGVPGLKG--LPGDPGREG--FPGPPGFMGPRGSKGAV---GPPGLDGLPGTSGLP GPVGPPGDRGLPGEVLGAQ-PGPRGDSGLPGRPGLKGPPGERGAPGFRGSQGMPGMPGQK GQPGSPGLSGQPGLPGPPGLH--GFPGAPGREGPLGPLGAPGFEGLPGDRGEPGDTGVPG P------VGMKGESGDRGDPGQQGARGHP--------GSPGFKGVSGMPGAPGLKGARGS PGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPP--II LPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMP-GIPGLSGIP--GLPGRPGHVK-GVKG DIGIPGVPGSPGFPGVP---------GSPGIMGFQGFTGSRGDKGAPGTAGLFGEVGPTG DFGDIG--DTIDLPGSPGLKGERGTTGAPGLKGFFGQKGAEGDVG------------FPG ITGLAGVQGPPGF---------KGQTGFPGLTGLQG----PQGDPGRAGAPGTKGDSGWP GNPGLPGLPGLRGIGGLHGLPGS------KGFPGSPGADL----HGDLGFPGPAGDRGDP GEANT--LPGPTGAPGQKGERGVPGGRGPMGSPGLQGFPGITPP---SNISGSPGDVGAP GIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGTKGWVGDP------GPQGRPGVF GLPGEKGPRGEPGFMGNIGPTGSVGDRGPKGPKGDRGLPGAPGPVGAPGIAGI-PQRIV- --------VERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGMSANPG FRGDQG------PMGLQGPVGFE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GEPGRPGSPGLPGMPGR----SI SIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDICYYASRNDKSYWLSTTAPL-P--MM-PVAEEDIRPYISRCSVCEAPAVAIAV HSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGAR GTCHYYTNKYSFWLTTIPEQTFQ-GTPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >KYO41305.1 hypothetical protein Y1Q_0006157 [Alligator mississippiensis] M-------YRTEPCMIEMGQPSCSPCHHVQCWL-----ELCATRMMMQVLLLLMLTTLLT GRVQAGGK-TYTGPCAGRDCS---GGC--QCFPEKGSRGQPGPLGPQGFPGPPGLIGIPG LEGPKGHKGERGQPGITGPKGDQGLRGVTGFPG---ADGVPGHPGQPGSRGKPGHDGCNG TTGDPGEQGILGPPGQFGFIG-AQGPKGQKGEPYVFP--PEIADKYRGEMGKPGIKGFQG PRGEPGLVGFIGPKGRPGKPGPPGLPGPQGEKGNRGLG--FYGKKGEKGEIGSEGPPGLP STGEF----------------TTSTDFSIDHCKGQQGMKGEKGEPGISGSH--------- ------ASRAEKGEEGIMGFPGQRGL---PGINGIPGPVGEAGPPGFYGSPGYDGPKGMK GEQGEKGI------------PGLPA----YVPYPIPRK----------GVRGDQGVTGFP GPRGDLGEKGNPGIPGRPGTSDG-----------------LDGLDKRGLPGEMGPKGYKG EPGFSAL-YPGIPGFPGQ---PGPKGFPGPAGPKGSLS---------------ISFGLKG RRGDPGAAGSRGFPGPRGDKGFKGETG-DC-KCTG---SDEVRKSSAGLP---GPPGFQG PPGEPGRKGEPGDQGQHGI---PGFPGAKGFPGETGYPGPRGQKGYSV---YITTKGSKG DPGDPGLAGVQ------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------GSKGAK---GIPG DPGLDGLQGLKG--FPGDPGQEG--LPGPPGFHGPRGERGPS---GLLGQQGDDGISGKP GLPGPDGPKGVAGEVLGAS-AGSIGDVGLPGLPGLKGPPGNQGVPGLQGAGGIPGSPGSK GEPGLQGPHGLIGLPGEPGSH--GFPGIPGHQGPAGRGGITGNIGSPGARGDHGEQGFPG P------VGMKGLSGDKGELGIPGVQGIP--------GKTGLPGIDGMHGLQGYKGAKGS PGIEGFKGMTGNRGFQGHKGVKGEIGFFGISGLKGEQGNPGSKGDRGEQGEPGKPP--KI DPSMLVEVKGEKGDSGQTGLKGDSGFKGLKGMP-GLPGEPGFP--GFPGQPSHVS-GAKG DIGSKGVTGSLGYPGQP---------GSPGIRGFPGSTGIRGEKGTEGFTGLYGESGLPG ESGTPG--DTINLPGIPGLKGEVGTPGSSGVRGSPGEKGQRGDPG------------FSG IEGLKGSQGLPGI---------KGQSGFPGLVGPPG----QQGDPGAPGLPGEKGTQGWP GFAGPTGLPGLRGISGLDGLPGT------KGLQGSPGLDD----YGPSGFPGGPGDKGQV GDPST--LEGARGGPGQKGERGNQGERGPTGSPGLDGIPGPPGV---SNISGIRGDIGSP GLYGVPGYKGEQGRRGIPSPPGSKGEIGQIGVVGEDGPKGTRGDP------GLTGKPGIL GSFGAKGQKGEQGVMGPVGTLGISGDTGPAGPKGNRGVTGIQGPPGSPGLTPL-PSKTL- --------AEVGAPGPHGQRGPQGIPGEIGPQGPLGDSGFRGAPGKQGLQGRSGIPALPG FRGDQG------PQGHQGPSGSE------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GIPGRPGSPGLPGMPGR----SV NIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPF LYCNPGDVCYYANRNDKSYWLSTTAPL-P--MM-PVAEEEIRPYISRCSVCEAPAVAIAV HSQDVSIPHCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGAR GTCHYYANKYSFWLTTI-EEQFQ-STPSADTLKAGLIRTHISRCQVCMKNL--------- ------------------------------------------------------------ ---------- >XP_018105335.1 collagen alpha-2(IV) chain isoform X1 [Xenopus laevis] M------------------TRTQSTKRCATGSKEYSYFLLKHHPVTW-CVLLVVLVTVFA GNAHAGGK-SYTGPCGGRDCS---QGC--QCLPEKGSRGQPGPLGAQGTPGPPGLIGIAG LQGHKGDKGERGFTGVTGPSGDKGHRGVTGFAG---ADGVPGHTGQGGPRGKPGHDGCNG TKGDGGDGGSHGPRGPPGIPG-GFGAKGQKGDPFHVS--IEVKNRLKGDPGEPGFNGIQG PRGFPGIAGFIGPQGNRGPRGPPGPPGPQGSQGNRGLG--YYGEKGETGDPGPPGEQSGP GVREQ----------------QHKNEILLLQYKGATGDQGEKGIPGDEGQQ--------- ------AFTGEKGEEGITGFPGQRGL---PGIDGARGASGEIGFPGTNGVPGLPGQNGKK GDHGERGP------------QGPVT----YVNGQKTGK----------GYEGDIGFPGQD GLYGDEGDLGDPGFPGQKGFPST----------------FPGPTGDTGLKGQRGPKGYPG DPGLPAF-QPGPPGIDGD---PGKEGPPGKPGYPG------------------GRIGMKG LPGPPGRDGHRGFPGSRGFKGNKGEQG-EC-KCFA---GDESSKGPAGEP---GPVGFPG LQGLSGRKGETGDRGVPGL---PGTPGTVGPAGPAGLPGPAGEKGDKV---FATEKGSKG VQGDPGVPGIPGHVGYPGRNGKDGIPGFPGPPGD-------------GVKGLPGHAGFPG QPGIAGARGETG------FPGPGFPGPKGMRGDSGDRGVS--GFPGIPGLPGPQG----- DCYQETDEENKIGKEGT-------GCRLIAPPAPTGSPGPPGLPGYNGLRGQK---GFPG PQGFDGVFGLKG--VKGDPGNDS--LPGPPGFPGQRGDRGNA---GFPGQPGAPGLSGKP GLKGVQGEKGVAGDRLGAP-PGEQGDTGLPGLQGLKGKQGDQGIPGLQGNFGTPGTPGNK GIQGSVGAPGAPGIPGPAALF--GFPGIPGNPGMLGPQGSMGPPGPPGPRGDEGEKGPPG P------VGMKGLPGEPGDQGFVGVRGKQ--------GAPGIPGLVGMHGLPGVKGIKGS PGMEGFHGMKGVKGRPAWRGIKGPSGNIGFPGIKGREGIPGAKGDRGERGPPGESP--QM LPEIMLLVKGEKGDQGVPGFKGTTGPKGSKGMP-GNPGQPGTP--GLPGIPSFEF-GDKG EIGSPGPVGHPGIPGEG---------GPRGIIGFPGFTGPRGTPGFSGLPGVPGERGSYG DTGERG--DTIDLPGEEGVKGQVGIPGLPGQHGIPGEKGIKGDQG------------VQG IEGMKGEPGQPGE---------RGFPGQQGLVGLPG----SQGSPGLPGVHGEKGSAGFP GFPGQHGFPGTRGIAGLDGLPGT------KGIQGQPGAEI----TGLKGFKGLSGERGQP GEASS--IVGTPGPAGLKGTKGDQGLPGLIGITGTVGVRGLPGF---SNRTGTPGDVGFP GPPGLPGFPGPMGIPGLPSKPGVKGEIGELGSQGDYGAKGIPGDQ------GKLGATGVA GMPGVKGWKGNAGFHGVVGESGHPGDQGPKGYKGDKGEHGFKGPPGQPGPVSE-PPLAT- --------AEHGSPGPQGIIGPEGVRGDIGPKGVVGSPGAPGQTGKEGLPGIPGWSAPPG NRGELG------LMGQRGLDGLK------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------GDSGVPGRAGLPGMPGR----SV NIGYLLVKHSQTDEEPMCPVGMAQLWTGYSLLYFEGQEKAHNQDLGLAGSCLQRFSTMPF LYCNPGDVCYYANRNDKSYWLSTTVPL-P--MM-PVVEEEIRPYISRCSVCEAPAVAIAV HSQDVSIPHCPDGWRSLWIGYSFLMHTAAGDEGGGQSLASPGSCLEDFRATPFIECNGGR GTCHYFANKYSFWLTTI-DQPFQ-SSPSADTLKAGLIQTHISRCQVCMKNL--------- ------------------------------------------------------------ ----------
BMGE Cleaned alignment of selected proteins >sp|P08572|CO4A2_HUMAN Collagen alpha-2(IV) chain OS=Homo sapiens OX=9606 GN=COL4A2 PE=1 SV=4 VAGPALLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGQGPKGQKGEPYALPRDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSKGEKGSEGEPGIRGI---SLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPG-MKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIEQSFQGSPSADTLKAGLIRTHISRCQVCMKNL >tr|A0A0H2UKP2|A0A0H2UKP2_DANRE Collagen, type IV, alpha 2 OS=Danio rerio OX=7955 GN=col4a2 PE=1 SV=2 -----SFTLIITVVILTSTTFSGVKKSTGPCGGRDCSQCYPEKGARGLPGPLGPQGPTGPKGRQGEPGLQGPKGMKGEHGEAGFVGPKGSVGMEGVPGFNGADGVPGHPGPSGARGKAGPDGCNGTRGDSGMPGFPGLEGGQGTPGPGMKGEKGDPLEVWMERFRGDPGPAGFPGIVGPTGDPGYRGLPGFQGPWG---PQGLKGAKGQKGERTKILKGVKGELGEIGEPGPPGVFSQGEKGKMGSKGDKGDLGYSTKAESGVSGFAGARGNPGLDGWPGPRGDTGLPGF---PGNNGRKGDVGEPGELVG--------GPPGPPGERGPVGNYGRKGAKGQPGPPGPELWGPEGPRGPKGASGETGEPGNPATQPGPPGPDGSPGSVGPPGPKG-----------SLEEYFKGSPGHRGRPGSAGKKGPKGDHGPGPPGPPGDSGDPGMAGEWGQQGDQGDPGTKGANGLPGF---PGTEGLPGPKGRKGELEAVQKGSAGDPGDPGHSGFPGEQGRPGIDGRDGEPGFRGPPGEGPVGEPGAKGYSGPPGRSGLIGPKGNPGQVLGATKGLSGLPGDDGQTGPDGRTGPPGPPG-----DC-----SSRG-GSQDPGPPGESGLPGPRGLEGFPGVPGPKGTAGFSGDLGDKGERGEPGRGGPPGPKGFTGPRGDLGYGTKGVKGPPGLSGKPGLDGASGGKGEHGEVFGASSGAPGDPGLPGHRGDTGLTGDPGLPGYFGMEGMPGMTGLKGESGPPGLQGEQGRPGPPGTFGFPGQTGYTGPPGPPGNIGEPGPSGRRGDQGEPGLIGARGVKGAIGDPGNIGVTGNIGPPGDQGETGGPGFFGLPGLKGSKGGQGMTGFPGKTGERGLKGFSGTKGEIGLPGHQGAKGAPGSPGQKGDRGLTGPPGDKPHITPHMKEVMKGSKGDHGNMGDPGFTGPRGTKGFPGIPGGEGKDGHPGEPSVVKGVKGLPGEPGLEGPKGMPGPGLPGIEGFPGMSGPKGNKGSSGAYGRPGDSGIKGFKGDLGPTISLPGSTGLRGETGHPGSTGAKGLYGMPGERGSSGLDGIEGMKGYQGEPGTVGPPGSDGLQGFPGSQGHKGRSGDPGQTGTTGIQGQPGQKGFPGLKGIFGLDGLKGQKGNQGVPGTDNWGQPGNPGTKGELGETGIPSTTTGVPGSLGHKGTTGDSGNKGEIGQRGVPGPQGQQGFSDIKGTQGDYGFPGIKGIPGFPGTRGTPGIPSPFGAKGDRGNVGDFGLFGEKGVQGDRGEKGSSGESGVSGRKGDKGEPGMMGFPGRRGFQGDRGPFGPKGDTGPPGFPGLPGAKGYPPVPQKLPGEQGPPGQMGIQGPSGRNGNPGPAGPPGDSGFVGPSGHKGMPGLPGIPGSPGFRGEPGSMGHSGLQGEGTRGRPGMPGPLGMAGRSVNVGYLLVKHSQSEEIPMCPQGMSLLWMGYSLLYFEGQEKAHNQDLGLAGSCLPRFNTMPFLYCNPGDICYYASRNDKSYWLSTTQPIPVEESEIKPYISRCSVCEAPSVAIAVHSQDTTIPNCPVGWRSLWIGYSFLMHTAAGDEGGGQSLASPGSCLEDFRTTPFIECNGAKGTCHYFANKHSFWLTSIDESFQSSPSSETLKAGQLLSRISRCQVCMKNL >NP_034062.3 collagen alpha-2(IV) chain precursor [Mus musculus] ASGPPLLLATVTVGLLAQSVLGGVKKLDVPCGGRDCSQCYPEKGARGQPGAVGPQGYNGPPGLQGFPGLQGRKGDKGERGVPGPTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTRGDAGPQGPSGSGGFPGLPGQGPKGQKGEPYALSRDKYRGEPGEPGLVGYQGPPGRPGPIGQMGPMGAPGRPGPPGPPGPKGQPGNRGLGFYGQKGEKGDIGQPGPNGIPSKGEKGDEGEQGIPGV---ISKGEEGIMGFPGIRGFPGLDGEKGVVGQKGSRGLDGFQGPSGPRGPKGERGEQGPPGPSVGARGDPGFQGAHGEPGSRGEPGEPGTAGPPGPDEDSMRGLPGEMGPKGFSGEPGSPARYLGPPGADGRPGPQGVPGPAGPPGPDGFLFGLKGSEGRVGYPGPSGFPGTRGQKGWKGEAGGGLPGLPGPKGFPGVNGELGKKGDQGDPGLHGIPGFPGFKGAPGVAGAPGPKGIKGDSTITTKGERGQPGIPGVHGMKGDDGVPGRDGLDGFPGLPGPPGDGIKGPPGDAGLPGVPGTKGFPGDIGPPGQGLPGPKGERGFPGDAGLPGPPGFPGPPGPPGTPGQRDCDTGVKRPIGGGQQIEGPTGSPGQPGPPGPTGAKGVRGMPGFPGASGEQGLKGFPGDPGREGFPGPPGFMGPRGSKGTGLPGPDGPPGPIGLPGPAGPPGDRGIPGEVLGAQPGTRGDAGLPGQPGLKGLPGETGAPGFRGSQGMPGMPGLKGQPGFPGPSGQPGQSGPPGQHGFPGTPGREGPLGQPGSPGLGGLPGDRGEPGDPGVPGPVGMKGLSGDRGDAGMSGERGHPGSPGFKGMAGMPGIPGQKGDRGSPGMDGFQGMLGLKGRQGFPGTKGEAGFFGVPGLKGLPGEPGVKGNRGDRGPPGPPPLILPG-MKDIKGEKGDEGPMGLKGYLGLKGIQGMPGVPGVSGFPGLPGRPGFIKGVKGDIGVPGTPGLPGFPGVGPPGITGFPGFTGSRGEKGTPGVAGVFGETGPTGDFGDIGDTVDLPGSPGLKGERGITGIPGLKGFFGEKGAAGDIGFPGITGMAGAQGSPGLKGQTGFPGLTGLQGPQGEPGRIGIPGDKGDFGWPGVPGLPGFPGIRGISGLHGLPGTKGFPGSPGVDAHGDPGFPGPTGDRGDRGEANTLPGPVGVPGQKGERGTPGERGPAGSPGLQGFPGISPPSNISGSPGDVGAPGIFGLQGYQGPPGPPGPNALPGIKGDEGSSGAAGFPGQKGWVGDPGPQGQPGVLGLPGEKGPKGEQGFMGNTGPSGAVGDRGPKGPKGDQGFPGAPGSMGSPGIPGIPQKIAVQPGTLGPQGRRGLPGALGEIGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPVGQGEPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPVAEEEIKPYISRCSVCEAPAVAIAVHSQDTSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYFANKYSFWLTTIEQNFQSTPSADTLKAGLIRTHISRCQVCMKNL >XP_038951185.1 collagen alpha-2(IV) chain [Rattus norvegicus] ASGLPLLLATVTVGLLAQSVLGGVKKSDVPCGGRDCSQCFPEKGARGQPGEVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGPTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTRGDAGPQGPSGTGGFPGLPGQGPKGQKGEPYALSRDKYRGEPGEPGSVGYQGPPGRPGPIGQMGPMGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDVGQPGPNGIPSKGEKGSQGEPGIPGI---TLKGEEGIMGFPGTRGFPGLDGEKGVSGQKGSRGLDGFQGPSGPRGPKGERGELGPPGPPAGARGDPGFQGAHGEPGSRGEPGDPGPVGPPGLDEDSKRGLPGEMGPKGFSGEPGPSAYYPGPPGADGKPGPQGLPGPAGPPGPDGFLFGLKGSEGRVGYPGPSGFPGGRGQKGWKGEAGPGLPGLPGPKGFPGVNGEFGKKGDQGDPGLHGIPGFPGFKGAPGIAGAPGPKGVKGDSTITTKGERGQPGIPGVHGMKGDDGVPGRDGLDGFPGLPGPPGDGIKGPPGDAGLPGTPGTKGFPGEVGPPGQGLPGPKGERGFPGDAGLPGPPGFPGPPGLPGTPGQADCDTGVKRPIGGGQQVEGPAGSPGQPGPPGPTGAKGIRGIPGFPGASGEQGLKGFPGDPGREGFPGPPGFMGPRGSKGAGLPGPDGPPGPIGLPGPAGPPGDRGIPGEVLGAQPGARGDAGLPGQPGLKGFPGEIGAPGFRGSQGMPGMPGLKGQPGFPGPSGQPGLSGPPGQHGFPGAPGREGPLGLPGSPGLGGLPGDRGEPGEPGEPGPVGMKGVSGDRGDAGVSGERGHPGSPGFKGMAGMPGIPGQKGDRGSPGMDGFQGMLGLKGRPGFPGIKGEAGFFGVPGLKGLPGEPGVKGNRGDRGPPGPPPLILPG-MKDIKGEKGDEGPMGLKGYLGLKGIQGMPGVPGLSGIPGLPGRPGFIKGAKGDIGVPGTPGLPGFPGVGPPGITGFPGFTGSRGEKGTPGVAGVFGETGPTGDFGDIGDTVDLPGSPGLKGERGVTGIPGLKGLFGEKGAEGDVGFPGITGMAGAQGSPGLKGQTGFPGLTGLQGPQGEPGRIGIPGDKGDFGWPGVPGRPGIPGIRGISGLHGLPGTKGFPGSPGVDAHGDPGFPGPTGDRGDRGEANTLPGPVGAPGQKGEQGIPGERGPVGSPGLQGFPGISPPSNISGLPGDVGAPGIFGLQGYQGPPGPPGPNALPGIKGDEGSSGAAGFPGEKGWVGDPGPQGQPGVHGLPGEKGPKGEQGFMGNTGPSGAVGDRGPKGPKGDQGFPGAPGSMGSPGIPGIPQKIAVQPGTMGPQGRRGLPGALGEMGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPIGQGEPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPVAEEEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYFANKYSFWLTTIEQNFQSTPSADTLKAGLIRTHISRCQVCMKNL >XP_038287383.1 collagen alpha-2(IV) chain isoform X1 [Canis lupus familiaris] AHSPALLLGAVTVGLLAQSVLAGVKKFDVPCGGRDCSQCYPEKGGRGQPGPVGPQGYTGPPGLQGFPGLQGRKGDKGERGSPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGPPGYDGCNGTRGDVGRQGPEGPAGFLGPPGQGPKGQKGEPYALSRDKYRGEPGEPGLVGFQGPPGRPGPIGQMGPVGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDMGLPGPNGIPSKGEKGSEGEPGRKGI---SLKGEEGIMGFSGTRGAPGYDGEKGSPGQKGSRGLDGYQGPDGPPGPKGEAGDRGPPGAPAGARGDPGFPGTHGDPGSRGEPGDPGPPGLPGPDEDGKRGLPGEMGPKGFIGDPGIPAPYPGPPGTDGKPGLRGPPGAAGPPGPDGFLFGLKGTEGSAGFPGPSGFPGARGQKGWKGDAGGGLPGLPGPKGFPGINGEPGRKGSQGDPGQHGIPGFPGFKGAPGTVGPPGPKGLKGDSAITTKGERGQPGVPGVPGLKGDDGVPGRDGLDGFPGLPGPPGDGIKGPPGDSGYPGAPGTKGAPGERGPPGLGLPGPKGERGFPGDAGLPGPPGFPGPPGPPGTPGQIDCDTGVKRPIGGDGQVRGPMGSPGLPGPPGPTGAKGLQGIPGLSGADGTPGLRGLPGDPGREGFPGPPGFVGPRGSKGAGLPGPDGHPGPTGLPGPVGPPGDRGLPGEVLGAQPGPRGDAGLPGHPGLKGPPGERGPPGFRGSQGMPGMPGLKGQPGFPGPSGQPGLPGPPGQHGFPGAPGREGPLGLPGASGRGGLPGDRGDPGDTGVPGPVGMKGLSGDRGDPGLLGERGPPGSPGFKGMSGMPGIPGQKGGRGSPGMDGFQGMVGLKGRPGLPGNKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPIIQPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGVPGLPGKPGHIKGIKGDIGIPGVPGLPGFPGVGPPGIIGFPGFTGSRGDKGAPGRAGLYGEVGPTGDFGDSGDIINLPGSPGLKGERGIAGAPGLKGFFGEKGTEGEVGFPGITGVPGVQGPPGPKGQTGFPGLTGLQGPQGDPGRAGVPGNKGDYGWPGIPGSPGFPGIRGISGLHGLPGTKGLPGSPGADIHGDPGFPGPAGDRGDPGEANIRPGPIGAPGQKGERGDPGGRGPIGSPGLQGFPGITPPSNMSGLPGDKGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGNPGAPGTPGTKGWGGDPGPQGRPGVFGLPGEKGPRGEPGFMGNTGATGSVGDRGPKGPKGDRGLPGAPGSVGSPGIAGIPQKITIQPGPVGPQGRRGPPGMQGEMGPQGPPGDPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPVGQGEPGRPGTPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPVAEDDIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIEQSFQGSPSADTLKAGLIRTHISRCQVCMKNL >NP_001155862.1 collagen alpha-2(IV) chain precursor [Gallus gallus] GARVSLLLVLLEVVLSAGRVDAGGKSYTGPCGGRDCSQCFPEKGARGQPGILGSQGFPGPPGLMGIPGLQGPKGHKGERGHPGISGPKGETGQRGVTGFPGADGVPGHPGQPGSRGKPGHDGCNGTVGDPGDPGTPGHSGFPGTIGQGPKGQKGEPYVLPASRHRGDPGDPGFTGFPGAPGTLGIQGPIGPRGVPGRPGPPGSPGPQGPQGNRGLGFYGEKGEQGSPGPPGPPGLPTKGERGEPGQKGEAGFPGVPEKGEEGVMGFPGQRGLPGNDGFPGLSGERGFPGFDGQPGQYGPRGGKGEQGEMGPPGPPAGVRGDPGSPGASGLRGEQGEQGDRGLPGIPGF-DADKPGLPGEIGPKGEKGEEGSPAYQAGPPGFPGKPGIRGPPGPPGTPG---SLFGLKGQEGTPGRPGVQGFPGPRGQRGPKGEEGRGSTGPRGPPGFPGTPGQPGRKGEPGDQGPHGIPGYAGAKGQSGQEGLPGPKGEKGDSYITTKGTKGIRGDPGLPGIRGEDGFPGRDGLDGLPGLPGLPGDGIRGLPGDPGYPGELGPKGFPGEIGLPGEGYPGPKGYRGLPGDRGTDGHPGPPGLPGPPGEPGQLDCGQVIEDFSRGEATVRPPKGSQGNPGLPGATGTKGARGFPGDPGPVGFPGLNGTRGDPGREGYPGPPGFIGPRGDRGPGLPGLQGHPGLMGKSGAPGLAGQKGAPGDVLGAAAGPRGDDGLPGFPGLKGAPGDQGIPGIRGADGNPGLPGPKGDPGLQGLPGLMGLPGTPGTHGFPGPPGNRGPDGGPGSQGPLGPPGARGEDGEQGFPGPVGMKGLSGDKGETGFPGLQGIPGVTGPPGISGMDGFPGDKGSRGSPGIDGFKGMPGLKGRPGIKGIKGEFGLLGTRGDKGAQGARGFKGDRGEQGPPGEPPKLKPSMMMEVKGEKGDAGETGTKGFFGIKGSKGMPGLPGKTGIPGSPGHPSYVPGVKGDIGAKGLTGLKGYPGPGSPGIRGFPGSTGGRGDKGAPGISGHFGTPGSHGEIGEPGDTINLPGMPGLKGEVGVPGLTGLRGGPGQKGEGGDPGLPGIEGLKGIQGVPGSLGQKGLPGLVGPPGQQGSPGTPGFQGEKGAPGWPGLPGQAGLPGLRGISGLHGLPGTKGLPGSPGPDGYGSAGFPGPVGDKGEAGEPSRVEGSQGPPGQKGDRGVPGVQGPFGIPGQDGLPGPPGISNISGYPGDTGSPGLDGVPGYPGLHGQPGIPAPPGSKGESGRAGVSGQAGPKGTRGDPGLPGRPGIPGYPGPKGRKGEQGVIGFIGTVGFPGDLGPIGPKGDRGLTGFQGPPGSPGLPPIPPRLVAEQGSPGPRGNAGPRGSPGDAGPQGPPGEPGLRGLPGEPGLQGRGGIPAPPGSRGEQGAMGFQGPVGFGQPGRPGSPGLPGMPGRSVSIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYANRNDKSYWLSTTAPLPVAEEEIRPYISRCSVCEAPAVAIAVHSQEASIPRCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYFANKYSFWLTTIDQPFQSKPSADTLKAGLIRSHISRCQVCMKNL >XP_024204109.1 collagen alpha-2(IV) chain isoform X1 [Pan troglodytes] VAGPA-LLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGQGPKGQKGEPYALPRDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSKGEKGSEGEPGIRGI---SLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAGARGDPGFPGAQGEPGSQGEPGDPGLPGAPGLDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGKGLPGLPGPKGFAGINGEPGRKGDKGDPGQHGLPGFPGLKGVPGNVGAPGPKGAKGDSTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAIGGDRQVGGPKGLPGLPGPPGPTGAKGLRGIPGFSGADGGPGPKGLPGDAGREGFPGPPGFIGPRGSKGAGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGERGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPG-MKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGAPGIPGLPGFPGVGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGEPGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPVAEDEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIEQSFQGSPSADTLKAGLIRTHISRCQVCMKNL >XP_024855939.1 collagen alpha-2(IV) chain [Bos taurus] AARPALLLGAVTVGLLAQSVLAGVKKLDVPCGGRDCSQCYPEKGGRGQPGPVGPQGYTGPPGLQGFPGLQGRKGDKGQRGAPGITGPKGDVGPRGVSGFPGADGIPGHPGQGGPRGPPGYDGCNGTVGDSGYAGPPGPGGFLGPRGQGPKGQKGEPYALSRDKYRGEPGEPGLVGLQGPPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDMGLQGPGGIPPKGEKGSQGEPGRIGV---SLKGEEGVVGFSGPRGAPGIDSEKGLPGQKGSRGLDGYQGPDGLPGPKGERGDPGPPGPPAGVRGEPGSPGAPGEPGDRGVPGDPGLPGRPGTDEDEKRGLPGEMGPKGFTGEQGFPALYPGPPGTDGQPGLRGPPGLPGPPGPDGFLFGLKGEKGSGGFPGSSGFPGARGQKGWKGDAGRGPPGLPGPKGFAGANGQPGSKGSQGDPGQHGVPGFAGFKGAPGNVGPPGPKGMKGDSTITTKGERGQPGVPGAPGLKGSDGIPGPPGLDGFHGLPGPPGDGIKGPRGDTGQPGAPGTKGLPGERGPPGLGLPGPKGERGFPGDAGLPGPPGFPGPPGLPGSPGQIDCDSGVKRPIGADGQVGGPKGSPGQPGLPGPPGAKGLRGIPGFSGADGAPGLKGLPGDPGREGFPGPPGFMGPRGSKGAGPPGLDGLPGASGLPGPVGPPGDRGLPGEVLGAQPGPRGDSGLPGRPGPKGPPGERGPPGFRGSQGMPGMPGQKGQPGSPGLSGQPGLPGPPGQHGFPGAPGREGPLGPPGAPGFQGLPGDRGEPGDTGVPGPVGMKGGSGDRGDPGQQGERGHPGHPGFKGVSGMPGAPGLKGARGSPGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPLIEPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGIPGLPGRPGQIKGVKGDTGIPGVPGSPGFPGVGSPGIMGFQGFTGSRGDKGVPGRAGLFGEVGPTGDFGDIGDTIDLPGSPGLKGERGTTGIPGQKGFFGERGTEGDIGFPGITGLAGVQGPPGFKGQKGFPGLTGLQGPQGDPGRAGAPGIKGDSGWPGNPGLPGLPGLRGISGLHGLPGSKGFPGSPGADVHGDPGFPGPAGDKGDPGEPNTLPGPTGAPGQKGERGAPGERGPIGSPGLQGFPGITPLSNISGSPGDVGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGSPGTKGWIGDPGPQGRPGVFGLPGEKGPKGEPGFMGNIGPTGSPGDRGPKGPKGDRGLPGAPGAVGTPGITGIPQRIAIERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGVSAIPGFRGDQGPVGLQGPVGFGEPGRPGSPGLPGMPGRSISIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPVAEEDIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIEQSFQGTPSADTLKAGLIRTHISRCQVCMKNL >XP_020921567.1 collagen alpha-2(IV) chain [Sus scrofa] ASGPALLLGTVMVGLLAQSVLAGVKKLDVPCGGRDCSQCYPEKGGRGQPGPVGPQGYTGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGSDGCNGTVGDTGYAGPVGPDGFLGPPGQGPKGQKGEPYALSRDKYRGEPGEPGLVGFQGPPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDVGQPGPNGIPSKGEKGSEGEPGRKGI---SLKGEEGIMGFSGSRGVPGFDGEKGSPGQKGSRGLDGYEGPDGYPGPKGERGDPGPPGAPAGARGEPGFPGALGEPGARGEPGDPGPPGLPGTDEDEKRGLPGEMGPKGYAGEPGAPALYPGPPGADGKPGLRGPPGPPGPPGPDDFLFGLKGAKGSMGYPGPSGFPGARGQKGWKGDAGGGLPGPPGPKGFPGINGEPGRKGSQGDPGQHGIPGFPGFKGAPGDAGPPGPKGMKGDSTITTKGERGQPGVPGVPGLRGDDGAPGRDGLDGFPGLPGPPGDGIKGPPGDAGHPGVPGTKGLAGDRGPPGLGLPGPKGERGFPGDDGLPGPPGFPGPPGPPGPPGQIDCDSGVKRPIGADGQVGGPKGSPGQPGPPGPPGAKGLRGIPGPSGADGAPGLKGFPGDPGREGFPGPPGFVGPRGSKGAGPPGLDGLPGPSGLPGPVGPPGDKGLPGEVLGAQPGSRGDPGLPGHPGLKGPPGERGAPGFRGSEGMPGMPGLKGQPGFPGPSGQPGLPGPPGQHGFPGAPGREGPLGPPGAPGFGGLPGDRGDPGDTGVPGPVGMKGLSGDRGDPGLLGERGHPGSPGFKGVAGMPGAPGPKGTRGSPGMHGFQGMLGLKGSPGLPGSKGEAGFFGVPGLKGLPGEPGVKGSRGDPGLPGPPPTILPG-MKDIKGEKGDEGPMGLKGYLGLKGIPGMPGIPGLSGVPGLPGKPGHVKGAKGDTGAPGVPGSPGFPGLGPPGIIGFPGFTGSRGDKGSPGRAGLYGEIGATGDFGDIGDTIDLPGSPGLKGERGTAGVPGLKGFFGEKGTVGDVGFPGITGLAGVQGPPGLKGQTGFPGLTGLQGPQGDPGRAGVPGAKGELGWPGNVGLPGLPGIRGISGLHGLPGTKGFPGSPGADVHGDPGFPGPAGDRGDPGEANTLPGPAGAPGQKGERGAPGERGPVGNPGLQGFPGITPPSNVSGLPGDTGAPGIFGPEGYRGPPGPPGPAALPGSKGDEGLPGIPGNPGGKGWVGDPGPQGRPGVFGLPGEKGPRGEQGFMGNTGATGSVGDRGPKGPKGDRGLPGPPGAVGAPGIVGIPQRIAVQRGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPVGQQGPVGQGEPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICHYASRNDKSYWLSTTAPLPVAEEEIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIEQSFQSSPSADTLKAGLIRTHISRCQVCMKNL >XP_008258402.1 PREDICTED: collagen alpha-2(IV) chain [Oryctolagus cuniculus] ASGSALLLGAVTAGFLAQSVLAGVKKSDVPCGGRDCSQCYPEKGGRGQPGPVGPQGYTGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGPPGYDGCNGTRGDEGPQGPSGTGGFPGSPGRTQRGRRVSPYALSRDRYRGEIGEPGLVGFQGPPGRPGPMGPMGPVGAPGRPGPPGPPGPKGHPGNRGLGFYGKKGEKGDIGAPGPNGIPFKGEKGSEGEPGAIGI---SLKGEEGIMGFSGSRGAPGLDGEKGSPGQKGSRGVDGYQGPDGPRGPKGQAGDPGPAGPPAGARGDPGFPGPHGDPGSRGEPGDPGPPGSPGLDEDEMRGLPGEMGPKGFAGEKGFPALYPGPPGVDGKPGLPGVPGPAGPPGPDGFLFGLKGAEGRVGYPGPSGFPGARGQKGWKGEAGGGLPGLPGPKGVPGLNGEPGSKGQQGDPGQHGIPGFPGFKGAPGLTGVPGPKGAKGDSTITTKGERGQPGVPGVPGMKGDDGVPGRDGLDGFPGLPGPPGDGIRGPPGDAGYPGIPGTKGGPGDVGPPGLGLPGPKGERGFPGDAGLPGPPGFPGPPGPPGTPGQIDCDTGVKRPPGGDGQAAGPKGLPGPPGPPGPPGAKGLQGIPGFSGADGPPGLKGLPGDPGREGFPGPPGFVGPRGSKGAGLPGPDGRPGPVGLPGPAGAPGDRGLPGEVLGAQPGPRGDAGLPGQPGLKGLPGERGPPGFTGSQGMPGMPGLKGQLGLPGPSGQQGLQGPPGQHGFPGAPGPAGPLGLPGAPGLEGLPGDRGEPGDTGVPGPVGMKGLSGDRGDAGFSGERGQPGNPGFKGMSGMPGTPGPKGERGSPGMDGFQGMLGLKGRPGLPGTKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPIILPG-MKDIKGEKGDEGPMGLKGHLGLKGIQGNSGVPWPGGNPGCLGRPGHIKSRKAKLAVPGVPGLPGRAGVGPSGHGAWPGIRGTRGDKGAPGIAGLYGELGPTGDFGDVGDTIDLPGSPGLKGEQGSAGVPGLKGFFGEKGVEGEVGFPGITGLTGAQGPPGLKGQTGFPGLTGLQGPQGDPGRIGVPGDKGDRGWPGAPGLPGFPGIRGIGGLHGLPGTKGFQGSPGADAHGDPGFPGATGERGDPGEANLLPGPLGVPGQKGERGVPGERGPAGSPGLQGFPGITPPSNISGLPGDKGAAGIFGLQGYRGPPGPPGPAALPGSKGEDGSPGAAGVPGSKGWAGDPGPQGRPGVFGLPGEKGPRGEQGFMGNTGATGAAGDRGPKGPKGDQGFPGAPGPVGSPGIIGLPEDRCPARGLWAPRERGGPPGAQGEIGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGHQGPVGQGEPGRPGSPGLPGMPGRSVSIGYLLVKHSQTEQEPMCPLGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPVAEDEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIERSFQGSPSADTLKAGLIRTHISRCQVCMKNL >XP_024086739.1 collagen alpha-2(IV) chain [Pongo abelii] VAGPALLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGQGPKGQKGEPYALPRDRYRGEPGEPGLVGFQGPPGRPGYVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSKGEKGSEGEPGIRGI---SLKGEEGIMGFPGPRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGPPAGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAEGGVGFPGLPGSPGARGPKGWKGDAGRGLPGLPGPKGFAGINGEPGTKGDKGDPGQHGLPGFPGLKGVPGNVGAPGPKGAKGDSTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAIGGDRQIGGPKGLPGLPGPPGPTGTKGLRGIPGFSGADGGPGPKGLPGDPGREGFPGPPGFIGPRGSKGAGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGSPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGERGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPG-MKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGAPGIPGLPGFPGVGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGPTGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGESGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGADIHGDPGFPGPPGERGEPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGVPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDAGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGHPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPVAEDEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIEQSFQGSPSADTLKAGLIRTHISRCQVCMKNL >XP_010726857.1 collagen alpha-2(IV) chain [Meleagris gallopavo] GARVFLLLVLLEVVLLAGRVDAGGKSYTGPCGGRDCSQCFPEKGARGQPGNLGSQGLPGPPGLMGIPGLQGPKGHKGERGHPGISGPKGEMGLRGVTGFPGADGIPGHPGQPGSRGKPGHDGCNGTVGDPGDPGTPGHSGFPGTIGQGPKGQKGEPYVLPASQYRGEPGDPGLTGFPGAPGRLGIQGPIGPRGTPGRPGPPGPPGPQGPQGNRGLGFYGEKGEQGSPGPPGPPGLPTKGERGEPGLKGEAGFPGVPEKGEEGVMGFPGQRGLPGNDGFPGLSGERGFPGFDGQPGQYGPRGGKGEQGEMGPPGPPAGVRGDPGFPGASGLQGEPGEQGDRGLPGIPGF-DADKPGLPGEIGPKGEKGEEGSPAYQAGPPGFPGKPGPRGPPGPPGTPG---SLFGLKGQEGTPGRPGAQGFPGPRGQRGPKGEEGRGSTGPRGPPGFPGTPGQPGRKGEPGDQGPHGIPGYAGAKGQSGQEGFPGPKGEKGDSYITTKGTKGIRGDPGLPGIRGEDGFPGRDGLDGLPGLPGLPGDGIRGLPGDPGYPGELGPKGFPGETGLPGGGFPGPKGYRGPPGDHGTQGNPGIPGLPGPPGEPGQIDCGQVIEDFPRGDATVRPPKGSQGNPGLPGATGTKGARGFPGDPGPVGFPGLNGTRGDPGREGYPGPPGFIGPRGDSGPGLPGLQGHPGLMGKSGAPGLDGQKGAPGDVLGAAAGPQGDAGLPGFPGLKGAPGDQGIPGIRGADGNPGLPGPKGDPGLQGLPGLMGLPGTPGTHGFPGPPGNPGPDGGPGSQGPLGPPGARGEDGEQGFPGLVGMKGQSGDKGETGFPGLQGIPGVTGPPGISGMDGFPGDKGSRGSPGIDGFKGMPGLKGRPGIKGIKGEFGLYGTRGDKGTKGAQGFKGDRGERGPPGEPPKPKPSMMMKVKGEKGDAGETGTKGFFGIKGSKGMPGLPGKTGIPGSPGHPSYVPGVKGDIGAKGLTGLKGYPGPGSPGIRGFPGSTGGRGDKGAPGSSGHFGTPGSHGEIGEPGDTINLPGMPGLKGEVGVPGLTGLRGGPGQKGEGGDPGLPGIEGLKGIQGVPGSLGQQGLPGLVGPPGQQGSPGTPGFQGEKGTPGWPGLPGQAGLPGLRGIGGLHGLPGTKGLPGSPGPDGYGSAGFPGPVGDKGEAGEPSRVQGSQGPPGQKGDRGVPGIQGPFGIPGQDGLPGLPGFSNISGYPGDIGSPGLDGVPGYPGLHGQPGIPAPPGSKGESGRAGVSGQAGPKGTRGDPGLQGRPGIPGYPGPKGRKGEQGVIGFIGTVGFPGDLGPIGPKGDRGLTGFQGPPGSPGLPPLPPRLVAEQGSPGPRGSAGPQGSPGDIGPQGPPGEPGFRGLPGEPGLQGRGGIPAPPGSRGEQGAMGFQGPVGFGQPGRPGSPGLPGMPGRSVSIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYANRNDKSYWLSTTAPLPVAEEEIRPYISRCSVCEAPAVAIAVHSQEASIPRCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYFANKYSFWLTTIDQPFQSKPSADTLKAGLIRSHISRCQVCMKNL >XP_034792866.1 collagen alpha-2(IV) chain [Pan paniscus] VAGPA-LLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGQGPKGQKGEPYALPRDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSKGEKGSEGEPGIRGI---SLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAGARGDPGFPGAQGEPGSQGEPGDPGLPGAPGLDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGKGLPGLPGPKGFAGINGEPGRKGDKGDPGQHGLPGFPGLKGVPGNVGAPGPKGAKGDSTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPTGTPGQIDCDTDVKRAVGGDRQVGGPKGLPGLPGPPGPTGAKGLRGIPGFSGADGGPGPKGLPGDAGREGFPGPPGFIGPRGSKGAGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGERGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPG-MKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGAPGIPGLPGFPGVGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGEPGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPVAEDEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIEQSFQGSPSADTLKAGLIRTHISRCQVCMKNL >XP_023108926.1 collagen alpha-2(IV) chain [Felis catus] VSSPALLLGAVTVGVLAQSVLAGVKKFDVPCGGRDCSQCFPEKGGRGQPGPVGPQGYTGPPGLQGFPGLQGRKGDKGERGSPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGPPGHDGCNGTRGDVGRQGPVGPGGFAGPPGQGPKGQKGEPYALSRDKYRGEPGEPGLVGFQGPPGRHGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLGFYGQKGEKGDMGQPGPNGIPSKGEKGSEGEPGRKGI---ALKGEEGVMGFSGIRGSPGFDGEKGSPGQKGSKGLDGYQGPDGPPGLKGEVGDRGPPGAPAGVRGDPGFPGAHGEPGSRGEPGDPGPPGPPGTDEDGKRGLPGEMGPKGFIGDPGIPALYPGPPGTDGKPGPRGPPGPPGLPGPDGFLFGLKGAEGNVGYPGPSGFPGARGQKGWKGDAGGGLPGPPGPKGLPGVNGEPGKKGSQGDPGQHGIPGFPGFKGAPGNVGPPGPKGVKGDSAITTKGERGQPGVPGVPGLKGDDGVPGRDGLDGFPGLPGPPGDGITGPPGDIGYPGTPGTKGAPGERGPPGLGLPGPKGERGFPGDVGPPGPPGFPGPAGPPGAPGQIDCDTGVKRPIGDDGQVGGPKGAPGLRGPPGPTGAKGLPGIPGPSGADGVPGLKGLPGDPGREGFPGPPGFVGPRGSKGVGLRGPDGHPGPTGLPGPVGPPGDRGLPGEVLGAQPGPRGDAGLPGHPGLKGPPGERGPPGFRGSQGMPGMPGLKGQPGFPGPSGQPGLPGPPGLHGFPGAPGQEGPLGLPGAPGRGGLPGDRGDPGDIGIPGPVGMKGLSGDRGDPGLLGERGPPGGPGFKGMSGIPGVPGPKGSRGSPGMDGFQGMVGLKGRAGLPGNKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPIIQPG-MKDIKGEKGDEGPMGLKGYLGLKGVPGMPGIPGLSGIPGLPGKPGHIKGVKGDIGVPGVPGLPGFPGVGPPGIIGFPGFTGSRGDKGAPGRAGLYGEVGPTGDFGDIGDTIDLPGSPGLKGERGIAGAPGLKGFFGEKGTEGEVGFPGITGVPGVQGPPGPKGQAGFPGLTGLQGPQGEPGRAGAPGDKGDYGWPGIPGSPGFPGIRGISGLHGLPGTKGFPGSPGVDAHGDPGFPGPAGDRGDPGEANTRPGPVGAPGQKGERGNPGERGPVGSPGLQGFPGITPPSNISGSPGDKGAPGIFGPEGYRGPPGPPGPAALPGRKGDEGNPGAPGNPGTKGWGGDPGPQGRPGVFGLPGEKGPRGEPGLMGNTGATGSVGDPGPKGPKGDRGLPGAPGSVGSPGIVGIPQKITVQPGPVGPHGRRGPPGAQGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDQGPMGQQGPIGQGEPGRPGTPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPVAEDEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIERSFQGSPSADTLKAGLIRTHISRCQVCMKNL >XP_027829588.1 collagen alpha-2(IV) chain isoform X1 [Ovis aries] AARPALLLGAVTVGLLAQSVLAGVKKLDVPCGGRDCSQCYPEKGGRGQPGPVGPQGYTGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGPRGVSGFPGADGIPGHPGQGGPRGPPGYDGCNGTMGDSGYAGPPGPGGFLGPRGQGPKGQKGEPYALSRDKYRGEPGEPGLVGLQGPPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDMGLQGPGGIPPKGEKGSQGEPGRIGV---SLKGEEGVMGFSGPRGAPGFDGEKGLPGQKGSRGLDGYQGPDGLPGPKGEMGNPGPPGLPAGIRGEPGSPGAPGEPGARGEPGDPGLPGRPGTDEDEKRGLPGEMGPKGFIGERGFPALYPGPPGADGKPGLRGPPGRPGPPGPDGFLFGLKGARGSGGFPGSSGFPGARGQKGWKGDAGRGPPGLPGPKGFAGANGQPGSKGSQGDPGPHGLPGFSGFKGAPGNVGPPGPKGMKGDSTITTKGERGQPGVPGVPGLKGTDGIPGPPGLDGFHGLPGPPGDGIKGPRGDAGQPGAPGTKGLPGERGPPGLGLPGLKGERGFPGDAGLPGPPGFPGPPGLPGAPGQTDCDSGVKRPIGADGQVGGPKGSPGQPGLPGPPGAKGLRGVPGFSGADGVPGLKGLPGDPGREGFPGPPGFMGPRGSKGAGPPGLDGLPGASGLPGPVGPPGDRGLPGEVLGAQPGPRGDSGLPGRPGLKGPPGERGPPGFRGSQGMPGMPGQKGQPGSPGFSGQPGLPGAPGQHGFPGAPGREGPLGPPGAPGFEGLPGDRGEPGDTGVPGPVGRKGGSGDRGDPGQQGERGHPGLPGFKGVSGMPGTPGLKGARGSPGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPIILPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGIPGLPGRPGHIKGVKGDTGVPGVPGSPGFPGVGSPGVMGFQGFTGSRGDKGAPGRAGLFGEVGETGDFGDIGDTIDLPGSPGLKGERGTTGIPGQKGFLGERGTEGDVGFPGITGLAGVQGPPGFQGQKGFPGLTGLQGPQGDPGRAGAPGIKGDSGWPGNPGLPGLPGLRGISGLHGLPGNKGFPGSPGADVHGDPGFPGPAGDKGDPGEANTLPGPTGAPGQKGERGAPGERGPIGSPGLQGFPGITPPSNISGSPGDIGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGIKGWVGDPGPQGRPGVFGLPGEKGPKGEPGFMGNIGPTGSPGDRGPRGPKGDRGLPGAPGAVGAPGIAGIPQRIAVERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGVQGKAGPQGRGGVSAVPGFRGDQGPVGLQGPVGFGEPGRPGSPGLPGMPGRSISIGYLLVKHSQTEKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYASRNDKSYWLSTTAPLPVAEEDIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIEQNFQGTPSADTLKAGLIRTHISRCQVCMKNL >XP_004054779.3 collagen alpha-2(IV) chain [Gorilla gorilla gorilla] LAGPALLLGTVTMGFLAQSVLAGVKKFDVPCGGRDCSQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGQGPKGQKGEPYALPRDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSKGEKGSEGEPGIRGI---SLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGKGLPGLPGPKGFAGINGEPGRKGDKGDPGQHGLPGFPGLKGVPGNVGAPGPKGAKGDSAITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKKAIGGDRQVGGPKGLPGLPGPPGPTGAKGLRGIPGFSGADGGPGPKGLPGDAGREGFPGPPGFTGPRGSKGAGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGERGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPG-MKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGAPGIPGLPGFPGVGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGTTGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGEPGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPLGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGERGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVTAVPGFRGDEGPIGHQGPIGQGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPVAEDEIKPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIEQSFQGSPSADTLKAGLIRTHISRCQVCMKNL >XP_011488241.1 collagen alpha-2(IV) chain isoform X1 [Oryzias latipes] -RHCGLPLLCVYIVILTSGVQAGGKKHSGPCGGRDCSKCFPEKGGRGQPGPLGPQGPQGPKGRPGDLGIQGQKGQKGDQGPGGVIGPKGSAGMTGVPGFTGNDGIPGHPGQGGPRGKPGADGCNGTKGEPGIPGIPGDYGIQGAAGPGRKGEKGDNLDVKMQRFRGDQGAPGFDGPFGPDGPKGGEGTRGPTGPKG---PPGPSGPPGPKGTMTKVLKGVKGEQGDVGQPGPPGNDTSGPPGEKGQ---KGQVGEIITGEPGIPGPPGPRGEMGRNGQPGLEGEFGERGP---TGIDGVKGVRGEPGVLILSGD-----GAPGPPGEQGPLGERGPVGDQGIPGRPGPYTFGPLGFKGEQGDKGRQGEPGFPAFRAGPPGADGRPGDRGPPGPTI-----------TWAEYYKGPPGPRGRPGTAGLKGPKGDHGRGLPGPSGQHGDPGMIGEFGREGDFGDPGPRGVDGFPGS---PGLPGPLGIKGRKGDIFATEKGFPGDSGDPGMDGFPGQLGTPGLHGRPGPPGFPGPPGEGPWGEPGDKGFPGRSGRPGVRGISGEPGQVFPGQKGLQGLPGDDGLPGYDGVPGPPGTPG-----GC-----SPTS-GGLLPGLPGAPGLPGSPGLPGFPGTQGLKGPQGFDGVGGEKGEQGDRGNGGSPGPAGFVGQRGDIGIGAKGLVGSPGVPGAHGRYGPKGEKGVHGEILGASAGPQGDPGLPGLQGLKGQDGEPGLPGYEGMGGMPGMIGFKGEKGSLGLSGEEGKPGIAGLYGFPGEPGTAGPPGPSGATGDPGLPGERGTDGDPGPPGPVGLKGMPGEFGEDGSPGEPGSPGDPGWPGTTGRPGPPGIKGGKGSSGMVGFDGKKGTPGLKGIIGVKGDAGLPGEQGLKGTMGVPGEKGDRGVKGPPGEKPQIPLHIIVDMKGVKGEHGSQGNPGFTGPRGSKGLPGVPGFDGVHGSPGDPSNDKGQLGDPGLQGLPGIKGMPGPGNRGVTGFEGMSGEKGIKGSAGAYGASGENGRKGAKGDAGPRIDLPGSPGLRGEVGLPGNPGLKGLFGSPGDQGGSGFDGIVGIKGIFGDPGIQGFPGSDGQKGAPGYQGQKGFSGLPGKDGLPGFPGFPGVKGYPGLKGLHGLHGLKGQKGISGTAGLNFPGQAGNPGVKGQKGESGNPNDQQGDSGIPGFKGFQGPTGEYGLPGLPGLRGPSGPDGIPNEPGSPGDPGFQGPAGFQGLPGARGVPGSDASPGQRGEPGLNGFPGFPGNQGFRGDPGPTGFRGPHGIFGKKGVKGEQGLMGIPGTTGPKGERGQTGFKGNTGLPGFPGQPGSQGPPPIPIRVPGERGPSGPRGLQGPLGIRGEPGPQGPPGDTGFIGPIGQKGMPGVSGTPGTPGFRGNFGQMGHPGLEGMGNRGNPGIPGIPGMPGRSISVGYLLVKHSQSEEKPMCPVGMSKLWDGYSLLYFEGQEKAHNQDLGLAGSCLPRFSTMPFLYCNPGDICYYASRNDKSYWLSTTAPLPVEENEIKPYISRCSVCEAPSVAIAIHSQGIDIPQCPAGWRSLWIGYSFLMHTAAGNEGGGQSLSSPGSCLEDFRTLPFIECNGAKGTCHYFANKHSFWLTSIDHSFHANPAPETLKAGQLRSRISRCQVCMKNL >XP_021152299.1 collagen alpha-2(IV) chain [Columba livia] SARIFLLLILMEVVLSAVKVDAGGKTYTGPCGGRDCSQCFPEKGSRGQPGLLGSQGFTGPPGLMGIPGLQGPKGHKGERGHPGIAGPKGEVGQRGVTGLSYEKSPTGHPGQPGSRGKPGHDGCNGTAGDPGDPGTPGVFGFPGTIGQGPKGQKGEPYILPASRYRGDPGEPGFNGFQGPPGTLGIQGPVGPRGERGRPGPPGPPGPPGPQGNRGLGFYGEKGEQGPPGPPGPPGLPTKGERGEPGQKGEAGTPGEAEKGEEGVMGFPGQRGLPGINGFPGLSGERGFPGFDGPPGAYGPRGSKGEPGEIGPPGPVSGARGDPGVPGVSGLQGDPGEEGDRGLPGLPGF-DGDKPGLPGEMGPKGEKGEIGSPAYQAGPPGFPGKPGLRGLPGPAGPPG---ALFGLKGQEGTPGRFGAQGFPGPRGQKGPKGEEGRGSTGSPGPPGFPGTPGQPGRKGEPGDQGPHGLPGYPGAKGFPGPHGFPGPKGEKGDSYITTKGTKGIRGDPGLPGIRGEDGFPGRDGLDGLPGQPGLPGDVIRGFPGDPGYPGELGPKGFPGEPGLQGEGLPGPKGYRGPPGDHGQDGSPGPPGLPGLPGEPGQLDCGQVFEDFSRGDATVRPPKGSQGKPGLPGATGEKGARGFPGDPGPVGYPGLNGTRGDPGREGLPGPPGFTGPRGDRGPGLPGLQGHPGLTGKPGAQGVPGLKGLPGDVLGAPAGSRGDAGLPGFPGLKGLPGDQGVPGIRGADGNPGLPGAKGEPGPQGLPGLMGLPGIPGTRGFPGPPGNPGPDGGPGPQGPVGPPGARGEDGEQGVPGPIGLKGLAGDKGDMGYPGLQGRPGVPGPRGVSGMDGFPGDKGSRGSPGIEGFKGMTGLKGRPGIKGIKGEFGPLGAQGDKGAQGARGFKGDRGDQGPPGEPPKLKPSMMMEVKGEKGDVGERGTKGFFGLKGSKGMPGLPGKTGIPGSPGHPSYVAGAKGDVGAKGLAGLKGYPGPGSPGIRGFPGSTGGRGEKGLPGISGQFGTPGVHGEIGEQE---EIXXXXXLKGEVGVPGLTGARGGTGQKGEGGDPGLPGIEGLKGTQGIPGSVGQEGLPGLVGAPGQQGSPGTPGFQGEKGTPGWPGLPGQPGLPGLRGISGLHGLPGTKGLPGSPGPDGYGSAGFPGAVGDKGDAGEPSRVEGSRGPPGQKGDRGVPA-----------------GISNISGYPGDKGSPGLDGVPGYPGLQGQPGIPAPPGSKGESGQPGVSGQTGPKGSRGDPGPVGTPGVRGYPGPKGRKGEQGVIGFMGTVGFPGDLGPIGPKGDRGVTGFQGPPGSPGLPPLPPRLVAEQGSPGPRGNMGPQGSPGDMGPQGPPGDPGFRGSPGEPGLQGRGGIPAPPGSRGEQGATGFQGPVGFGQPGRPGSPGLPGMPGRSVNMGYLLVKHSQSEQEPMCPTGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYASRNDKSYWLSTTAPLPVAEEDIRPYISRCSVCEAPAVAIAVHSQEASIPHCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIDQPFQSKPSADTLKAGLIRSHISRCQVCMKNL >XP_017911852.1 PREDICTED: collagen alpha-2(IV) chain [Capra hircus] AARPALLLGAVTVGLLAQSVLAGVKKLDVPCGGRDCSQCYPEKGGRGQPGPVGPQGYTGPPGLQGFPGLQGRKGDKGERGAPGITGPKGDVGPRGVSGFPGADGIPGHPGQGGPRGPPGYDGCNGTMGDSGYAGPPGPGGFLGPRGQGPKGQKGEPYALSRDKYRGEPGEPGLVGLQGPPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDMGLQGPGGIPPKGEKGSEGEPGRMGV---SLKGEEGVMGFSGPRGAPGFDGEKGLLGQKGSRGLDGYQGPDGLPGPKGEMGDPGPPGLPAGVRGEPGSPGAPGEPGARGEPGDPGLPGQPGTDEDEKRGLPGEMGPKGFTGERGFPALYPGPPGADGKPGLRGPPGRPGPPGPDGFLFGLKGATGSGGFPGSSGFPGARGQKGWKGDAGRGPPGLPGPKGFAGANGQPGSKGSQGDPGPHGLPGFSGFKGAPGNVGPPGPKGMKGDSTITTKGERGQPGVPGVPGLKGTDGIPGPPGLDGFHGLPGPPGDGIKGPRGDAGQPGAPGTKGLPGERGPPGLGLPGPKGERGFPGDAGLPGPPGFPGPPGLPGAPGQTDCDSGVKRPIGADGQVGGPKGSPGQPGLPGPPGAKGLRGVPGFSGADGVPGLKGLPGDPGREGFPGPPGFMGPRGSKGAGPPGLDGLPGASGLPGPAGPPGDRGLPGEVLGAQPGPRGDSGLPGRPGLKGPPGERGPPGFRGSQGMPGMPGQKGQPGSPGFSGQPGLPGAPGQHGFPGAPGREGPLGPPGAPGFEGLPGDRGEPGDTGVPGPVGRKGGSGDRGDPGQQGERGHPGLPGFKGVSGMPGTPGLKGARGSPGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPIILPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGIPGLPGRPGHIKGVKGDTGVPGVPGSPGFPGVGSPGVMGFQGFTGSRGDKGAPGRAGLFGEVGETGDFGDIGDTIDLPGSPGLKGERGTTGIPGQKGFLGERGTEGDVGFPGITGLAGVQGPPGFQGQKGFPGLTGLQGPQGDPGRAGAPGIKGDSGWPGNPGLPGLPGLRGISGLHGLPGNKGFPGSPGADVHGDPGFPGPAGDKGDPGEANTLPGPTGAPGQKGERGAPGERGPIGSPGLQGFPGITPPSNISGSPGDIGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGIKGWVGDPGPQGRPGVFGLPGEKGPKGEPGFMGNIGPTGSPGDRGPRGPKGDRGLPGAPGAVGAPGITGIPQRIAVERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGVSAVPGFRGDQGPVGLQGPVGFGEPGRPGSPGLPGMPGRSISIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYASRNDKSYWLSTTAPLPVAEEDIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIEQSFQGAPSADTLKAGLIRTHISRCQVCMKNL >XP_006017292.1 collagen alpha-2(IV) chain [Alligator sinensis] -----VLLLLMLTTLLTGRVQAGGKTYTGPCAGRDCSQCFPEKGSRGQPGPLGPQGFPGPPGLIGIPGLEGPKGHKGERGQPGITGPKGDQGLRGVTGFPGADGVPGHPGQPGSRGKPGHDGCNGTTGDPGEQGIHGPPGQFGFIGQGPKGQKGEPYVFPADKYRGEMGEPGIKGFQGPQGEPGLVGFIGPKGRPGKPGLPGLPGPRGEKGNRGLGFYGVNGEKGERGSEGPPGLPSKGQQGMKGEKGEPGISGSAEKGEEGIMGFPGQRGLPGINGIPGPVGEAGPPGFYGSPGYDGPKGMKGEQGEKGIPGLPAGVRGDQGVTGFPGPRGDLGEKGNPGIPGRPGTDGLDKRGLPGEMGPKGYKGEPGFSAPYPGIPGFPGQPGPKGFPGSAGPKGSSSISFGLKGCRGDPGAAGSRGFPGPRGDKGFKGETGKSSAGLPGPPGFQGPPGEPGRKGEPGDQGQHGIPGFPGAKGFPGETGYPGPRGQKGYSYITTKGSKGDPGDPGLAGVQGDDGLSGRDGTDGFPGPTGLPGDGTRGLPGDPGFPGPPGVKGFPGDAGLPGVGLPGPKGFHGLPGDHGTYGKSGPPGPPGPPGDPAQLDCDQVPEDLSRGNGRVRAPAGQPGKPGLPGSTGSKGAKGIPGDPGLDGLQGLKGFPGDPGQEGLPGPPGFHGPRGERGPGLLGQQGDDGISGKPGLPGPDGPKGVAGEVLGASAGSIGDVGLPGLPGLKGPPGNQGVPGLQGAGGIPGSPGSKGEPGLQGPHGLIGLPGEPGSHGFPGIPGHQGPAGRGGITGHIGSPGARGDHGEQGFPGPVGMKGLSGDKGELGIPGVQGIPGKTGLPGIDGMHGLQGYKGAKGSPGIEGFKGMTGNRGFQGHKGVKGEIGFFGISGLKGEQGNPGSKGDRGEQGEPGKPPKIDSGMLVEVKGEKGDSGQTGLKGDSGFKGLKGMPGLPGEPGFPGFPGQPSHVTGAKGDIGSKGVTGSLGYPGQGSPGIRGFPGSTGIRGEKGTEGFTGLYGESGLPGESGAPGDTINLPGIPGLKGEVGTPGSSGVRGSPGEKGQRGDPGFSGIEGLKGSQGLPGIKGQSGFPGLVGPPGQQGDPGAPGLPGEKGTQGWPGFAGPTGLPGLRGISGLDGLPGTKGLQGSPGLDDYGPSGFPGGPGDKGQVGDPSTLEGARGGPGQKGERGNQGERGPTGSPGLDGIPGPPGVSNISGIRGDVGSPGLYGVPGYKGEQGRRGIPSPPGSKGEIGQIGVVGEDGPKGTRGDPGLTGKPGILGSFGAKGQKGEQGVMGPVGTVGISGDTGPTGPKGNRGVTGIQGPPGSPGLTPLPSKTLAEVGLPGPHGQRGPQGIPGEIGPQGPLGDSGFRGAPGKQGLQGRSGIPALPGFRGDQGPQGHQGPSGSGIPGRPGSPGLPGMPGRSVNIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYANRNDKSYWLSTTAPLPVAEEEIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIEEQFQSTPSADTLKAGLIRTHISRCQVCMKNL >XP_015821737.1 PREDICTED: collagen alpha-2(IV) chain isoform X1 [Nothobranchius furzeri] QRSRGLLLLCLSLTILYPGVDAGGKKHSGPCGGRDCSQCFPEKGARGLPGPLGPQGFVGPVGRPGDPGIQGPKGQKGDQGIGGIVGPKGSMGMTGVPGFDGLDGIPGHPGQAGPRGRPGADGCNGTHGESGLPGLPGFIGPPGTLGQGRKGEKGDTLDIKMQRFRGDPGTPGSSGIFGPMGERGWEGNRGPIGPKG---PPGPPGPPGPKGTMTKYLKGVKGEPGDIGPQGPPGNYTPGQPGLKGD---KGEIGADNKGETGMMGNAGLRGDSGRDGLTGLRGDPGEPGP---TGRDGTKGVRGDPGELISSG------GPPGPPGETGPQGERGPIGDQGFPGPPGPDFFGPFGFTGDKGDKGQRGERGWPAVFAGPPGIDGRVGPIGPPGPKA-----------SLEVLFAGDPGWRGQPGRGGLKGQKGDHGRGLPGPAGDPGDAGIIGEFGREGDLGDTGPRGQDGLPGS---PGTNGLQGPKGRKGNTVATQKGLPGDPGEAGKDGPAGVPGSPGPDGLSGFPGNRGLPGEGPRGQHGDKGYPGRPGAPGAAGLRGVPGQDVTGIKGQRGLPGDDGISGYVGVPGTPGAPG-----GC-----SPTGEGGQVPGPPGLPGVPGVSGPPGAQGLPGLKGAVGVAGAKGEKGEQGEQGTGGSSGPPGFPGPRGDHGVGRKGSIGVPGFPGHSGRYGVQGEKGSHGEVLGASPGSQGDPGLPGDQGEKGPIGNPGNPGYSGMGGMPGMIGFKGEKGSPGLIGEEGRPGPAGTHGFPGDPGRVGLPGPFGETGQPGITGDRGTQGDPGPPGPTGLKGTPGEHGDFGATGEPGLPGDPGQPGGSGRPGHPGLKGSKGSHGMSGFEGMMGNPGQKGLGGLKGEAGVSGEVGLKGLLGKQGAKGERGLTGPRG---AIAVQMLVNVKGAKGDHGHQGMPGFTGPRGSKGVYGVPGFPGSDGLPGEPSKEKGQRGDPGAQGLPGFKGMPGIGNRGITGFEGMSGNKGIKGSPGAYGALGEDGRKGAKGDKGLRIDLPGNPGLRGEDGFAGEPGLKGLSGPTGDMGPTGFDGIEGIKGTVGDPGLAGIPGSDGQKGTPGNQGQKGFPGIPGKEGQPGFPGFSGIKGYPGLKGLYGLHGLKGHKGDQGTPGLEGFGRPGEPGHKGQKGEGGVHNDQPGFPGAVGSKGYQGPQGDIGHPGQPGLPGLAGPDGTPDIPGQRGDPGFSGPTGHQGVPGSRGLPGLDALPGERGVQGEPGAPGFPGTKGFRGDPGQSGYKGPHGVSGRKGVKGDQGVMGVPGQIGTKGDRGPSGPKGNTGIPGFPGPTGNRGPAPLPVITPGERGPPGVQGIMGPKGNRGEPGPQGPPGDSGFMGPIGERGMPGISGTPGVPGFRGEPGHMGHFGLQGKGYRGNPGIPGFPGMPGRSVSVGYLLVKHSQSDQTPMCPVGMSKLWDGYSLLYFEGQEKAHNQDLGLAGSCLPRFSTMPFLYCNPGDLCYYASRNDKSFWLSTTASLPVEESEIKPYISRCSVCEAPSVAIAVHSQDITIPQCPAGWRSLWIGYSFLMHTAAGNEGGGQSLSSPGSCLEDFRTAPFIECNGAKGTCHYFANKYSFWLTTTEQEFHSQPASQTLKAGQLLSHISRCQVCMKNL >XP_020769119.1 collagen alpha-2(IV) chain [Odocoileus virginianus texanus] AARPALLLGAVTVGLLAQSVLAGVKKLDVPCGGRDCSQCYPEKGGRGQPGPVGPQGYTGPPGLQGFPGLQGRKGDKGERGAPGTTGPKGDVGPRGVSGYPGANGIPGHPGQGGPRGPPGYDGCNGTMGDAGSAGPQGPGGFLGPPGQGPKGQKGEPYALPRDKYRGAPGEPGLVGMQGPPGRPGPIGQMGPVGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGEMGLQGPGGIPPKGEKGSGGEPGRIGI---SLKGEEGIMGFSGSRGAPGFDGEKGSPGQKGSRGLDGYQGSDGLPGPKGETGDPGPPGLPAGVRGEPGSPGQPGEPGARGEPGDPGLPGRPGTDEDEKRGLPGEMGPKGFTGERGFSAVYPGPPGADGKPGLRGPPGRPGPPGPDGFLFGLKGARGGGGFPGSAGFPGARGQKGWKGDAGRGPPGLPGPKGFAGINGQPGSKGSQGDPGQHGLPGFPGFKGAPGNVGPPGPKGMKGDSTITTKGERGQPGVPGVPGLKGGDGIPGPPGLDGFHGLPGPPGDGIKGPPGDAGQPGAPGTKGLPGERGPAGLGLPGPKGERGFPGDAGLPGPPGFRGPPGLPGAPGQIDCDSGVKRPIGADGQVGGPKGSPGQPGLPGPPGAKGLRGVPGFSGADGAPGLKGLPGDPGREGFPGPPGFMGPRGSKGAGPPGLDGLPGTSGLPGPVGPPGDRGLPGEVLGAQPGPRGDSGLPGRPGLRGPPGERGPPGFRGSQGMPGMPGPKGQPGPLGLSGQPGLPGPPGLHGFPGAPGREGPLGPPGAPGFEGLPGDRGEPGDTGVPGPVGMKGESGDRGDPGQQGARGHPGSPGFKGVSGMPGAPGLKGARGSPGMDGFEGMLGLKGRPGIPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPIIQPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGIPGLPGRPGHVKGVKGDTGIPGVPGSPGFPGVGSPGIMGFQGFTGSRGDKGAPGRAGLFGEVGPTGDFGDIGDTIDLPGSPGLKGERGTTGAPGLKGFFGEKGAEGDIGFPGITGLAGVQGPPGFKGQTGFPGLTGLQGPQGDPGRAGAPGTKGDSGWPGNPGLPGLPGLRGIGGLHGLPGSKGFPGSPGADIHGDLGSPGPAGDRGDPGEANTLPGPTGAPGQKGERGVPGERGPIGSPGLQGFPGITPPSNISGSPGDVGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGTKGWVGDPGPQGRPGVFGLPGEKGPRGEPGFMGNIGPTGSVGDRGPKGPKGDRGLPGDPGPVGAPGIAGIPQRIAVERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGMSANPGFRGDQGPVGLQGPVGFGEPGRPGSPGLPGMPGRSISIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYASRNDKSYWLSTTAPLPVAEEDIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYTNKYSFWLTTIEQTFQGTPSADTLKAGLIRTHISRCQVCMKNL >XP_030285421.1 collagen alpha-2(IV) chain isoform X1 [Sparus aurata] QHDTGLLLLCVSIAILASGVHGGGKKHSGPCGGRDCSQCFPEKGARGQPGPLGPQGHQGPQGRAGDPGIEGPKGQKGDHGRGGIVGPKGNVGMTGVPGFSGNDGIPGHPGQAGPRGKPGADGCNGTQGDSGFPGQTGYNGSPGSPGPGRKGAKGDSLELSMERFRGDPGTPGVNGIFGPPGHPGWQGNRGIPGPKG---PTGPPGPRGPKGTMTKVLKGLKGEQGDIGPPGPQGNSTYGPSGPRGEKGLKGEIGDDNKGETGIMGFPGHRGESGLDGSPGLRGDPGYPGP---KGRDGIKGVRGDAGLLISSGP-----GPPGPPGEQGPVGERGPVGDQGTPGPPGRQLFGPFGFKGEAGEKGQQGEPGRPAVSAGPPGTSGRPGGRGPQGPKG-----------TWAEYFKGAPGGRGRPGNAGYKGVKGDHGAGQPGPAGEPGDAGMIGEFGQEGDVGDPGPRGEDGFPGH---AGLSGVPGPKGQKGAESATQKGYSGDPGVPGPNGGLGVPGAPGRDGLPGFPGSRGLPGEAPSRLRGDKGFPGLPGRPGVAGEAGEPGEGLKGIKGQRGLPGDDGITGYEGVPGTPGSPG-----GC-----SPRGDGEQIPGPPGLPGAPGPTGLPGFPGSRGEKGVQGPLGVTGEKGESGEQGIGGRPGPPGFAGPRGDLGNGRKGSLGVPGFPGVSGRHGSQGEKGVHGEILGASSGSPGDPGPPGFRGNKGQSGEPGEPGYPGMPGMPGMIGFKGEKGPAGLQGEEGRPGPAGRYGYPGDPGRAGPPGPPGATGQPGLTGERGTEGDPGPPGPIGLKGVPGTYGADGATGEYGLSGDPGLPGADGRPGLPGMKGYKGSTGMEGFEGMRGDVGVKGFSGSRGEPGVFGEVGPKGVTGHQGLKGDRGLRGPPGDKPHIPAQIIVDMKGAKGDHGNEGTKGFIGPRGSKGLPGVPGSEGYHGLPGDPNNEKGVQGDPGPQGLPGLKGMPGLGNKGISGFGGMPGKTGIKGSPGAYGASGEKGRKGIKGERGPRIDLPGVPGLRGELGFSGDPGQKGLFGNPGDRGTLGFDGIEGRKGVSGEPGIPGNTGTDGQKGSPGSQGPKGFPGEPGKQGLPGFPGFRGEKGFPGLKGLYGLDGLKGQKGFQGKPGLDITGPAGESGAKGEKGEGGDPNNQPGDPGTAGLKGFQGSPGDHGQTGPPGLRGPRGPDGKPDKPGSRGDPGFVGAKGYEGFPGARGYPGVDAPPGEKGITGGSGFPGFPGIKGDKGDQGAPGYKGQHGVSGKKGVKGEQGFMGFPGVTGAKGERGPAGPKGSTGPPGFRGFPGNQGPLPIPIKVPGERGPPGPRGIQGPQGVRGGIGPHGPPGDGGFMGPVGQKGMPGISGRPGVPGFRGGVGPMGHPGLQGRGLRGNTGVPGLPGMPGRSVSVGYLLVKHSQTEQTPMCPVGMSKLWDGYSLLYLEGQEKAHNQDLGLAGSCLPRFSTMPFLYCNPGDLCYYASRNDKSYWLSTTAPLPVEEGEIKPYISRCSVCEAPSVAIAIHSQDITIPQCPVGWRSLWIGYSFLMHTAAGNEGGGQSLSSPGSCLEDFRTTPFIECNGAKGTCHYFANKHSFWLTSIDQSFHTEPSSETLKAGQLLSRISRCQVCMKNL >XP_040192142.1 collagen alpha-2(IV) chain [Rana temporaria] KRCLRVLLLIALVMGFPGSVDAGGKSYTGPCGGRDCSQCFPEKGSRGQPGQLGGQGPQGPQGIIGIAGLQGRKGDKGERGHPGISGPTGDKGQSGVTGFSGANGVPGHVGQGGSRGKPGHDGCNGTKGDAGEAGFQGIRGPLGPLGPGIKGHKGDPFYISKKRIRGEPGEPGLAGYPGPNGPPGKVGFIGPMGELGLPGPAGPPGSAGPPGSKGIGFFGQKGEMGDPGKPGPPGVPCLAEKGEKGERGDYGAPGEGELGEEGIMGFPGTRGPSGNDGAPGEKGENGLPGLNGNPGIPGFKGLKGEEGERGVPGPPTGEQGDPGFPGNVGLDGETGEKGSPGLPGLMGLGPPGFPGLTGEKGQKGYQGNSGLPAFQKGRDGEPGEPGPRGPSGFPGYPG---GRIGRKGAKGSPGNDGSDGYPGYAGLKGLKGEQGKGPAGDPGPVGFAGLTGEIGSKGEKGDRGGPGLPGAPGIKGPAGFNGLPGPVGEKGDGIATEKGAKGERGTPGTQGAEGFEGFSGKDGLYGIPGSSGPPGDAPKGLLGEPGFAGSPGLEGARGEPGLPGVGFPGPKGAHGAPGQPGRNGSPGIPGLQGLPG-----DCEPGEDNQVG---QPPAPAGTRGPPGLPGFNGVRGVKGHIGQSGADGMHGFKGVRGDTGPDSLPGPQGFPGRRGDRGKGTSGLPGERGPSGNPGAQGYQGTKGIPGDVLGAPSGSRGDVGWPGFSGLKGVQGDAGFPGFQGINGRPGTPGLKGISGDPGIPGTPGLPGPSGNGGFPGMQGKPGKPGTVGHSGLPGSPGSRGDEGEQGNPGQAWKKGEAGDEGELGIAGIRGRIGDPGFPGLTGMGGHPGVKGVRGSSGMGGFEGMKGEKGRSAFDGPKGQYGNFGLPGERGNPGVSGNKGDRGEEGPPGPEPKMEESMLEKMKGEKGILGVPGSPGVPGLNGTKGMPGHPGNPGLSGSPGMPSFDTGNKGDAGQSGFLGFPGSQGPGPPGIRGFPGFTGPRGSKGMPGLYGIPGYKGEFGDKGQTGDSMDLPGERGNKGVIGDHGFPGQRGIHGEKGFSGDAGFPGIEGMSGDPGQPGQKGQTGLPGLLGISGPQGDPGFPGVHGEKGNSGFSGLPGQQGFPGFRGRSGLDGLKGTKGLQGPAGVDVFGVSGIKGTPGQKGDQGEQNTLAGLPGNTGGIGARGEPGVPGVTGLPGLIGVRGLPGASNLSGIPGDIGPAGPPGQPGHPGPQGRPGVSSRPGEKGDPGPFGIQGIVGERGTPGDRGFQGFTGIPGYLGLKGQKGQQGIIGDFGLPGFSGDTGPKGPKGDRGSTGLQGAPGEPGLPPVPVRMKVDSGPVGVFGIVGPQGIPGDMGPRGPEGAKGVHGPQGKEGVPGIPGRSAAPGARGDLGSMGQRGPEGGGTSGVPGSAGHPGMPGRSVNIGYLLVKHSQTEQEPMCPVGMAKLWSGYSLLYFEGQEKAHNQDLGLAGSCLQRFNTMPFLYCNPGDVCYYASRNDKSYWLSTTASLPVVEDEIKPYISRCTVCEAPAVAIAFHSQDSSIPFCPDGWRSLWIGYSFLMHTAAGDEGGGQSLSSPGSCLEDFRATPFIECNGARGTCHYFANKYSFWLTTIDNNFHSSPASDTLKAGLIRTRISRCQVCMKYL >CAE1304334.1 COL4A [Sepia pharaonis] HRRAEFQVLTWLILIFLYITNSVANAQNSECGQICASRCIGEKGSRGPHGPIGPRGVQGVRGYPGPEGLTGPKGDKGRAGPPGPSGPKGDRGKIGIPGYPGVPGIPGIPGEPGPRGPAGLDGCNGTQGSSGLPGIPGSPGKTGPPGPGNPGRKGDSG---LKGLKGEPGRPGI-GLNGPQGPPGKHGISGPVGPIGPKGSKGSKGNQGMKGHKGISFRGDPGPRGPRGPPGKPVVPL-GEKGEIGDRGYEGLPGEGMKGEKGVAGIAGPRGKQGIPGVPGPRGIKGDRGMEGLPGISGLPGLKGEPGRDGPPGPPGGPAGMKGNPGPVGPRGLKGEIGGPGIPGPPGNGKDGLLGRPGFPGAKGEPGQKGEPGI--GDPGLDGIPGKDGRPGAKGDTGLKGGPTGPKGDKGGRGFKGQDGINGLNGLPGPKGDKGRGDPGLDGPPGRSGLSGSSGEKGEPGEPGEDGLYGPPGERGYPGDSGLPGSSGPKGQK----EPVQAPV-IKGEKGNAGLPGIAGLSGNKGASGPPGPTGPGEMGFAGLPGADGRPGEAGRPGRPGVPGYGLSGPKGQPGEPGQPGVSGPKGDKGDPGRKG--------------------EPGDRGFPGAKGLPGLPGPKGFDGLPGRPGLDGMKG---ERGQNGLPGTAGPRGYNGPRGAKGEGLAGLPGEAGITGAKGDRGFSGLKGS--------KGQSSNASVPGSPGRKGERGLDGLPGQRGLDGTPGQRGDRGPTGEDGLPGLPGRDGAKGEPGI-GLPGRPGPQGP---PGLNGIPGSSGLKGEPGSSGLPGLKGKDGLPGQPGLPGLDGEPGIMGPVGKPGLPGLPGSKGERGAVGFSGEPGRNGAPGLPGVKGERGDDGLIGLPGRNGLDGLPGMKGASGLPGLSGMKG--EPGRV-ASKGEKGEPGLSGLPG---ERGLDGTPGRDGLPGIQGEKGEP----GI----GQSGLPGEDGPP--GLSGLPGQRGPVGPKGDAGPSGFPGMKGEPGYPGKPGLSG-------------------IPGNDGLPGQKGDRGFPGQDGLPGLKGEPSTNGLPGLPGEKGESGPRGPPGQRGYAGMKGDRGLDGFPGAKGNSGLPGTSGIPGADGLPGLSGLPGFPGSDGIGDKGDRGFPGEKGDEGPLNLIKGERGFTGNTGPKGDKGEQGPNGLNGIEGQKGEKGSSEIPGLKGEPGYPGAKGEPGLPGAPGLDGLPGRDGVKGADGRPGPPGNDGLPGEKGLPGLSGEPGLQGQPGLDGLKGEPGLPGLPGLSGEKGDSGLSGLPGENGRSGLKGERGDTGRPGEPGPAVGPKGNKGLPGLTGPPGFPGLKGDTGLPGNPGLPGLAGERGLPGEAGLTGLPGADGRPG---LQGKPGLGTPGLMGPPGPRGPAGRSAAVGFLFARHSQTTEVPVCPDGLTKLWDGYSLLYLEGNERSHHQDLGWAGSCIKRFSTMPFLFCDFNDVCNYASRNDKSYWLSTNAPMPVGQNEIPPYISRCAVCDSSTNVIAVHSQTLNLPDCPQGWEGLWIGYSFAMHTGAGAGGGGQSLSSPGSCLEDFRATPFIECSGHAGTCHYFANKYSFWLTTIEQSQQRAPQPQTLKAGSLRTRVSRCQVCMKKI >ACK77661.1 RE33133p [Drosophila melanogaster] WKTAGRNEPKFPIDDSYDIVDSAGV-ARGDLPPKNCTKCIAEKGNRGLPGPLGPTGLKGEMGFPGMEGPSGDKGQKGDPGPYGQRGDKGERGSPGLHGQAGVPGVQGPAGNPGAPGINGKDGCDGQDGIPGLEGLSGMPGPRGYAGLGSKGEKGEPAKENAKGEKGEPGWRGTAGLAGPQGFPGEKGERGDSGPYGAKGPRGEHGLKGEKGASCYGKPGAPGIKGEKGEPA------MGPRGDMGQKGEPGLVGRGQKGEKGLPGGPGDRGRFGPPGSTGQKGDRGEPGLNGLPGNPGQKGEPGRAGATGKPGPPGGPQGLNGVDGLPGPQGYNGQKGGAGLPGRPGNGSIGPIGHPGPPGPEGQKGDAGLPGYIQGSKGDAGIPGYPGLKGSKGERGFKGGTPGAAGAPGQKGDAGRPGTPGQKGDMGIKGDVGKGTSGLPGIPGKDGARGPPGERGYPGERGHDGITGPPGEKGEDGRTGLPGATGEPGKPLSLIEPLKGDKGYPGAPGAKGVQGF---KGAEGLPGIPGPKGEGEKGLSGAPGNDGTPGRAGRDGYPGIPGQSIKGEPGFHGRDGAKGDKGSFGRSGEKGEPG-----SC-----------ALAKGNKGEPGQTGMPGPQGEDGSP------GERGYTGLKGNTGPQGPPGVEGPRGLNGPRGEKGNGAVGVPGNPGKDGLRGIPGRNGQPGPRGEPGISRPGPMGPPGLNGLQGEKGDRGPTGPIGFPGADGSVGYPGDRGDAGLPGVSGRPGIVGEKGDVGPIGPAGVAGPPGV---PGIDGVRGRDGAKGEPGSPGLKGDRGAPGNDGPKGFAGVTGAPGKRGPAGIPGVSGAKGDKGATGLTGNDGPVGGRGPPGAPGLMGIKGDQGLAGAPGQQGLDGMPGEKGNQGFPGLDGPPG--LPGDA-SEKGQKGEPGPSGLRGDTGPAGTPGWPGEKGLPGLAGRAGPP----GEKGDQGRSGIDGRDGIN--GEKGEQGLQGVWGQPDEKGSVGAPGIPGAPGMDGLPGAAGGAVGYPGDRGDKGEPGLSGLPGLKGETGPVGLQGFTGAPGPKGERGIRGQPGLRGDKGSQGERGYTGEKGEQGERGLTGPAGVAGAKGDRGLQGPPGASGLNGIPGAKGDRGEIGYPGVTIKGEKGLPGRPG----------RNGRQGLIGAPGLIGERGLPGLAGEPGLVGLPGP---IGPAGSKGERGIAGSPGQPGQDGFPGAPGLKGDTGPQGFKGERGLNGFEGQKGDKGDRGLQGPSGLPGLVGQKGDTGYPGLNGNDGPVGAPGERGFTGPKGRDGRDGTPGLPGQKGE---PGMLPGPKGEPGQPGRNGPKGEPGRPGERGLIGIQGERGEKGERGLIGETGNVGRPGPKGDRGEPGERGYEGAGLIGQKGEPGAPAPAALDYLTGILITRHSQSETVPACSAGHTELWTGYSLLYVDGNDYAHNQDLGSPGSCVPRFSTLPVLSCGQNNVCNYASRNDKTFWLTTNAAIPVENIEIRQYISRCVVCEAPANVIAVHSQTIEVPDCPNGWEGLWIGYSFLMHTAVGNGGGGQALQSPGSCLEDFRATPFIECNGAKGTCHFYETMTSFWMYNLESSQPERPQQQTIKAGERQSHVSRCQVCMKNS >XP_038051105.1 collagen alpha-2(IV) chain-like isoform X1 [Patiria miniata] GRTLGVVAVLLLAFVGSSIAQK------ADCGA--TCNCKGRQGQRGTPGQIGPEGDRGARGILGYQGVQGPKGDIGDPGAAGPRGQKGDRGMTGVPGFPGLNGYTGLPGPKGPYGNPGVAGCNGPKGEDGIPGIGGY-GPRGPPGNGPKGSKGEPAPYTIQGRRGDPGFDGPDGNPGQQGRNGYPGQQGDRGFKGFQGSRGFDGYQGPPGANSPGYKGPKGEPGAQGPKGRSASPFPGTKGDRGETGAKGDVGMGMKGEKGVLGIAGPRGPTGLPGAPGFIGDRGFDGTRGQDGVPGYQGFRGDVGDDGPPGEIGGARGAVGDPGEEGLPGRLGEIGGPGPVGRPGLGKQGFQGSPGEQGQKGQPGDKGAPGFRAGPVGMDGAFGRVGERGRKGVVGAQGGPIGETGPRGPKGVVGASGPQGPSGGKGFPGRPAPGDIGFPGRFGPDGERGPTGEKGANGEPGYLGRQGQPGFPGLRGPRGLKGDTGDRGTP----------RSIP-VRGYKGERGEQGLKGQIGEPGTQGIQSPGEMGEKGRKGGRGTDGAPGPAGEDGVDGERLDGPRGPKGVMGEDGRF---GFLGPKGQKGEP--A-------------ERIPGPRGEPGPQGAKGGRGPAGFQGFPGPFGDMGIRGTKGGSGFPGVPSFPGPKGFPGPRGDKGLGIQGEIGRQGRQGEPGNPGFPGRDGMRGDRGEDGSGSVGPTGFPGDEGPQGIKGTNGFNGLPGQSGFPGFQGMNGERGDPGPFGPQGERGLKGATGFPGRQGSPGRDGPRGPQGPTGAEGPPGDRGVFGGIGSNGEDGFPGERGQQGERGEKGFPGRPGLFGARGEFGDPGLDGLPGNPGQKGNAGFPGFSGRPGEPGPQGLPGKDGLPGLIGETGDPGRTGQVGLFGDFG-----EPGDI----GEPGEDGADGLIG---PLGQDGRPGSPGFPGPIGNRGFS----GITGMVGDKGGVGEQGRPGNGEKGYRGLRGFRGVTGFEGDLGLIGRPGPRGPQGPAGQKG-DSGVPGTPGLFGEVGPPGDPGSRGSKGIKGSSFNPNEPG-TGEKGAKGEKGDQGSRGLNGLRGTVGDRGPSGEPGNQGYDGYDGFDGIAGMRGDPGLPGLFGVEGLPGMPGEDGNPGI--KGRQGLPGPQGPKGVIG----FSGFSGFPGSAGTDGRPGERGPRGNKGFPGLPGVPGFIAPAGEPGEDGPRGPDGPKGFVGQPGQPGFPGFSGLKGPKGEPGLTGL-GSPPVLGPPGAKGIQGPTGVPGLKGRVGDIGFPGPVGELGPFGLKGYPGYPGRQGRPGLPGFNGPKGQ---PGDQP-----DAQKGVKGDSGDPGPFGIRGRPGRPGFAGVDGSVGLKGMKGDFGDPGEPGSIGPQGLRGDFGDGPQGFKGGKGVGGEEGSPRPQGFIVVKHSQSRNIPRCDVGMTQLWTGYSLLYTEGNEKAQHQDLGLAGSCLPRFSTMPYVFCNFNEICNFAQRNDKSYWLATSEAIPVEGNGIRPYISRCAVCETPTQVIAVHSQDTTLPDCPRNWRSLWIGFSFAMYTSAGADGGGSALASPGSCLEDFRATPFIECNG-RGRCFFYRNTYSFWLTTVDADAMRPQESQTLKAGSLRSRVSRCQVCQKIL >NP_001022662.2 Collagen alpha-1(IV) chain [Caenorhabditis elegans] -----LLGLTAAVVLLSSFCQDRIHDAAAACKG--CAVCPGTKGERGNPGFGGEPGHPGAPGQDGPEGAPGAPGMFGAEGDFGDMGSKGARGDRGLPGSPGHPGLQGLDGLPGLKGEEGIPGCNGTDGFPGMPGLAGPPGQSGQNGPGRPGLSGPPGEGGRKGVKGESGRSGVPGLPGNSGYPGLKGAKGDPGPYGLPGFPGVSGLKGRMGVR---TSGVKGEKGLPGPPGPPGQPGVGPAGVKGEKGRDGPVGPGLKGQKGDLGDAGQRGKDGVPGNYGEKGSQGEQGLGGTPGYPGTKGGAGEPGYPGREGPLGGGKGLPGHDGLPGPVGPRGPVGAPGAPGQPGIGFAGEPGLPGEPGDCGYPGEDGLPGYIQGPPGLDGQDGFPGIPGDIGDPGYSGGPPGMTGLPGEPGMPGRIGVDGYPGPPGNNGERGAGDPGFPGYPGPPGPNGDHGDCGMPGAPGKPGSAGSDGLSGSPGLPGIPGYPGMKGEA-EIVGPMENPAGIPGLKGDHGLPGLPGRPGSDGLPGYPGGPGQGEPGLAGIDGKRGRQGSLGIPGLQGPPGDSFPGQPGTPGYKGERGADGLPGLPGAQGPRGIP----------------APVAGQPGVDGMPGLPGDRGADGLPGLPGPVGPDGYPGTPGERGMDGLPGFPGLHGEPGMRGQQGEGIDGDCGEPGLDGYPGAPGAPGAPGETGFGF---PGQVGYPGPNGDAGAAGLPGPDGYPGRDGLPGTPGYPGEAGMNGQDGAPGQPGSRGESGLVGIDGKKGRDGTPGT---RGQDGGPGYSGEAGAPGQNGMPGDQGYPGSPGQDGYPGPSGIPGEDGLVGFPGLRGEHGDNGLPGLEGECGEEGSRGLDGVPGYPGEHGTDGLPGLPGADGQPGFVGEAGEPGTPGYRGQPG--EPGNL----AYPGQPGDVGYPG---PDGPPGLPGQDGLPGLNGERGDN----GD-SYPGNPGLSGQPGDAGYGVPGPPGYPGITGMPGLKGESGLPGLPGRQGNDGIPGQPG-LEGECGEDGFPGSPGQPGYPGQQGREGEKGYPGIPGQPGLKGENGLDGQPGYAGQLGTPGDVGYPGAPGENGDNGNQGRDGQPGLRGESGQPGQPGLPGRDGQPGPVGPDGYPGAPGQDIYGPPGQAGQDG----------YPGLDGLPGAPGLNGEPGSPGQYGMPGLPGGPGE---SGLPGYPGERGLPGLDGKRGHDGLPGAPGVPGVEGVPGLEGDCGEDGYPGAPGAPGSNGYPGERGLPGVPGQQGRSGDNGYPGAPGQPGIKGPRGDDGFPGRDGLDGLPGRPGREGL---PGPMAGQPGENGYPGEKGYPGLPGDNGLSGPPGKAGYPGAPGTDGYPGPPGLSGMPGHGGDQG---FQGAAGRGNPGLPGTPGYPGSPGGAPSRGFTFAKHSQTTAVPQCPPGASQLWEGYSLLYVQGNGRASGQDLGQPGSCLSKFNTMPFMFCNMNSVCHVSSRNDYSFWLSTDEPMPVTGTAIRPYISRCAVCEVPTQIIAVHSQDTSVPQCPQGWSGMWTGYSFVMHTAAGAEGTGQSLQSPGSCLEEFRAVPFIECHG-RGTCNYYATNHGFWLSIVDQDKQRKPMSQTLKAGGLKDRVSRCQVCLKNR >XP_039251035.1 collagen alpha-2(IV) chain-like [Styela clava] -----FIVIIGIICIQEATARKRKRNIKGPCAGRDCRFCVSEKGNRGFPGRQGDVGTTGPPGFPGPEGLSGPKGEKGYPGRIGARGQSGSRGETGAPGYAGVNGLPGHPGEQGPVGHPGLDGCNGTEGDLGPRGEAGPPGLPGPVGDGAPGEKGEPAYVDIKGASGEDGPIGPEGRPGIQGPVGQMGPMGYDGPPGPPGPPGRKGQKGDEGNEGIGYQGEKGEKGSIGTAG--GRPDPGRNGSKGYKGEKGDIGFGETGEKGVRGPAGPRGPSGVPGVNGFNGRKGEPGDDGRPGTDGAQGLKGERGVPGSDGPSGGETGIPGLDGQSGLHGEKGERGNRGPAGSPGDGLDGVPGPAGLPGDKGSRGDVGAPGRVKGESGKDGMPGLRGLQGPRGRPGESGGPTGDVGAKGAKGLKGEMGPTG---LMGMKGDHGPGSRGPPGYPGRNGLPGIPGREGERGPPGENGAMGTPGDLGPRGFSGIPGPPGRKGEPGDIFKAQKGEQGVPGGQGPPGLDGLPGRAGGIGGPGARGEKGEGPIGKPGKPGPQGSDGERGNPG---RPGRDVEGTPGARGLKGESGRPGLPGITGYPGKQGPP--GEA-----------LEEKGLMGLPGPPGLPGSKGDTGDMGRPGVDGLAGVVGESGEPGPPGLPGLPGPKGFPGETGDKGGGPPGRDGYDGDYGVPGPPGEKGVKGERGVSDIRGTGGEGPKGNPGKGGGKGPVGEPGTPGEPGKMGADGKPGPDGEPGLIGPAGRLGPPGQKGESAFEGRPGDRGPTGPRGPPGLIGVTGPKGEIGGAGPPATKGMKGFPGLPGKYGEKGFTGPPGEPGRPGFEGFPGPNGMMGVIGSVGLPGPPGKMGQKGSYGPEGPKGDTGREGIPGDVGGRGDVGSKGPKGEKGQPGEALVTIVGQLMAS-----------------KHGEPGAPGERGLPGLPGMIGMT----GKKGEEGDPGKKGEPGEAGPGLPGRPGLDGLNGEDGETGEPGLPGLIGESGEKGDVGRPG-PNGLPGPSGETGQ------PGRDGPEGSPGLAGLDGLNGMNGDKGTKGRPGLVGISGMPGTRGIRGDRGFTGPPGTPGEKGMVGFPGRNGIDGLNGRTGLSGPTGTKGESGLDGLDGTDGKGRPGFSDVPGPAGSIGLPGLPPGESGLPGLSGSQGRQGDRGDVGLPGLGGRQGFPGDAGLPGFPGEKGEAGLNGRQGLPGPPGPPGPEGEIGLPGNAGERGMRGMNGNPGLPGRDGSPGESGSPGDIGERGDKGMKGMSGLTGIQGPDGAKGNAGLQGQIGRPGFPGRPGERGDAGPPGRSLPENVPPGPKGEKGRRGLPGLMGLEGEPGPSGIEGFKGEPGIPGRNGINGIPGPRGERGPTGLTGPQGPGLDGARGTKGRTGKPGKFRPAGHLIVRHSQTVDVPTCPGGTSKLWSGFSMLYLSGSERAHGQDLGSTGSCLRRFNTMPFLYCNVNEVCNYASRNDKSYWLATTLPIPV-ETGLEEYVSRCTVCESQSIAMAFHSQSDMIPDCPNGWKGLWFGYSFVMHTASGADGSGQSLSSPGSCLEDFRATPFIECNGARGHCFFYNNQFSYWLTTISKEEQTSPKKETLKAGNLRTRVSRCQVCAKVL >XP_006563187.2 collagen alpha-5(IV) chain [Apis mellifera] NATRGTCVLALLVVTWIPVTEA------VICRD---SNCTGIKGGAGYPGIPGLQGPEGPPGDIGPDGPPGPKGEKGAGGEYGGMGEKGYRGEQGIQGFPGAAGLPGKPGSPGVMGPDGLDGCNGTDGRAGSPGIPGVHGERGPPGMGDYGPIGEPGDGGVKGVRGNPGMNGLEGYPGSYGIPGEMGYPGETGDMGFRGSPGLPGMQGDVGDTVYGIKGAEGEQGDRGEPGPPSNGETGPKGMRGDAGERGRKGEGIKGTKGEQGDDGPRGKEGPPGPAGEKGEKGAPGYAGKPGPDGFDGELGDGGNQGPPGEPGGNPGEPGTPGLPGKVGYIGPPGPPGPPGSSGLGEMGLQGPPGAPGIPGTVGLKGYPGLIVGPPGPDGKPGVPGLPGDRGDPGVQGGPPGERGLPGIPGLPGPDGWPGLPGLKGVKGFKGQGDSGLDGYPGTPGYPGLPGPRGFKGVQGKRGIVGPRGLEGDSGRPGVAGPQGPKGER-RLIVPDKKIIGTPGDIGDKGYPGIEGPTGPRGEPGFRGDTGPGELGPPGRPGGDGYPGINGIPGEKGTPMEFLKGEPGSPGIPGLRGPPGDKGAKGERGISS-------------------QLKGEKGYKGERGDPGEDGAKGPEGWPGDEGFIGPSGIPG------SPGRQGPVGLKGYPGMPGDGPRGAPGTPGSEGFVGFPGRVGNKGDRGDPGSNQYGDYGLMGWTGEKGNVGDAGPMGYRGRPGPDGTKGAKGSKGAPGSAGIPGLQGVKGQRGD----RVQGSKGMPGI---HGQPGMPGRMGEVGIPGPDGTKGLKGEIGFMGRRGDDGDIGPPGYLGRDGIPGLPGPPGPDGDVGEIGEPGPRGWLGLEGLSGPMGAKGEQGDVGPVGIPGIVGLPGSKGISGDPGPVGLDG--LPGEN-AFSGPQGDIGEPGFMG---EVGAPGLPGMDGRPGLPGEPGLATDGFGLRGEKGEAGINGLNGLPGPGEIGDMGLDGLKGARGDWGLKGRPGIPGSPGLHAVKGERG-PIGPPGIEGLKGKRGLDGDPGRMGLPGMPGDQGHRGLMGAPGPKGYVGEPGLGGDFGMPGLNGLPGEKGERGEQGFVGLPGRKGMKGNIGYRGPDGFPGVPGFPGLPGDEGPPGFPGI--SGQFAEPGEDG----------RPGMDGIPGTPGIPGQKGAPGEYGPNGPIGITGDVGFRGPKGLAGDMGPRGFDGYPGAPGLQGMPSLPGLPGPKGYPGEIGLPGI-SIKGESGERGLDGFDGRPGT---KGIRGDSGLSGFVGLPGAKGEPGDVGEPGIIGLPGPPGPKGPKGDRGMP----SPFPRKGLPGDTGPPGLPGFPGLPGMLGEPGEDGLPGREGEPGMVGLPGLPGPEGEEGPAGYTGPPGVGRQGLPGSPGISGNPAPPRNRGFYFARHSQSEMIPLCPPNTIKLWDGFSLLHVRANGKSHGQDLGTAGSCVVKFNTMPFTFCNLNNQCNYADREEFSYWLSTTEPMPIPAPQVGRYISRCSVCEAPTRAIAVHSQTMAIPQCPGGWEELWIGYSFLMHRDVGNGGGGQSLVSPGSCLEEFRIRLFIECRS-KGTCNYFSTATTFWLTTIKDYEMRKPIPQTLKTDH-TSRVSRCVVCLRRR >NP_999631.1 3 alpha procollagen precursor [Strongylocentrotus purpuratus] -----FVCLSLLIIVFAYWADA------AACVG-CLSICNGTKGERGDRGYVGFPGPPGPGGFPGVEGPPGYKGQKGNLGIAGSGGPKGFRGSLGNPGIPGIPGIPGEPGQEGPPGEPGIPGCNGTKGERGPSGPTGF-GQPGSPGRGDPGPQGPPGDTTLKGIKGEPGRLGRDGYPGTPGDSGPTGPKGISGDPGLLGSKGTRGLKGEPGQPGVQYQGGKGEKGSVGTQGLPGESCPGPKGDQGEYGDKGDKGFGLKGEKGLSGPQGPRGKIGKDGTPGNQGMKGSPGIPGNPGPTGFNGQLGDKGDRGPPGPPGGSAGPRGYPGEKGRTGYDGKAGQPGPPGSAGDGMPGPNGFQGLPGRDGPKGDKGMAGLIQGLPGMDGRDGPAGLPGQVGDAGPQGGPKGQTGRDGPRGIPGDVGSSGQPGLPGPQGSKGPGQSGEIGQPGQPVYNGNSGPSGPKGDRGLRGLTGRDGQDGPQGPPGSTGRPGNKGQL------LQGEVGFT-EPGPRGIQGDPGLKGDNGLNGEPGPPCEGALGPPGPPGRDGVPGYQGQKGDRGLPGDSLRGSNGEKGDQGPRGERGTYGSPGDKGEVV-------------------YPKGEPGNPGTAGPPGPAGPTGNQGLPGDQGPDGYQGEKGSQGQSGPPGIPGSPGEKGAQGIPGDGQPGQPGPTGPLGNPGIPGAFGEKGDFGPQGNPGQGLRGLTGQPGQPGIGGERGNIGDPGTRGRDGIPGQAGGKGETGPGGLPGGPGIKGEPGL----SIPGQDGSSGT------------------------PGRDGAPGGPGEPGPSGPRGEPRITRLNGQRRPPGQPGDNGAPGNDGEPGPAGQIGVKGSPGPLGPGGSQGPPGSPGPIGAPGEKGERGGMGTPGSPGPSG--SPG----AKGEPGLPGPLGEKESRGPGGVPGSKGESGIPGRSGGIGSP----GSIGLPGLNGVKGEPGIPGNGEPGPAGFKGFQGLLGVKGDFGIKGQMGFPGPKGDNAQMG----IPGQNGGEGFPGRSGIPGPQGAPGSPGEPGTDGSNGGPGSKGEKGQPGIKGVKGDPGRTGPEGAKGNPGLPGIPGESGDAGLPGSEGRPGQPGTSGPPGPPGPNGETGTPGDPGPRGYGTPGEDGIPGVKGDSG----DPGLMGLPGGPGLPGPGGPPGESGFPGVRGVKGIPGTPGLSAL-GIKGEPGFPGLKGDSGQPGLNGGSGSIGLPGMKGTKGETGPVG-PRSPLPPGPKGEIGIPGANGDRGDKGDRGEPGRPGFQGRPGESGSPGLNGQMGDPGGPGFQGLKGSKGEPGPIPGDRGGPGPDGPQGPPGRDGRPGPQGPPGLTGDKGTPGVQGNPGVSGVPGEPGLKGEQG---FRGQNGQGDPGFPGTKGEAGIPGS--SSGFFITRHSQTTSIPQCPQGTAKMWHGYSLLFVQGNERGHGQDLGKPGSCLKRFSTMPFLFCNINNVCHVASRNDYSYWLSTTEPMPIRGGQLQPFISRCVVCEAPAQVLTVHSQTVNIPDCPDRWGVLWIGYSFMMHTGPGGEGSGQMLSSPGSCLEDFRSSPFIECHG-DGKCNYYATTYTFWLSSITGNAQTMPQSETLKAGSLRTRVSRCAVCLRNQ >XP_031568877.1 collagen alpha-2(IV) chain-like [Actinia tenebrosa] ------------------------------------------------------------------EGIMGPRGIKGDKGEFGAEGAKGPRGKVGRPGFPGQPGIPGIPGNEGARGEHGEPGCNGTQGDRGSDGQPGRPGRIGVKGIGPPGPRGFPGEAPLKGVKGEPGPFGPVGPQGPRGDVGVPGPKGDIGPPGPLGIPGPPGPTGKKGEMGIRFEASKGDKGAKGVPGPKGQPNKGPPGLRGLPGPRGEKGEGQKGNKGEPGNDGPVGKDGDIGLPGPMGXRGFPGDIGLPGEPGPVGPSGAPGAPGPPGPPGGFPGIKGARGPPGPPGNIGPLGPPGPQGFKGDGMKGPPGKPGAQGDPGTPGDRGPRGFIQGDPGMDGL------PGPRGETGGKGGPPGEKGEPGFPGVQGNDG------PSGPQGPKGKGSVGLPGENGAVGPPGEIGVPGAPGKPGTTGRSGRPGPMGPSGDPGIKGKDGAKGDR-ELIK-IKGEKGTPGTSGPPGPFGPPGIRGRPGADGQKGSPGPGSIGLKGAPGVNGKDGLKGAPGFSGEKGLFVQGRPGXPGPQGERGPLGPKGLPGPTGEKGTS--WDN-----------TQXPGDPGVPGKDGLKGEKGDNGKGGLPGPPGARGVDGAKGGEGQPGPPGPPGPQGQRGPIGEKGDGPPGSQGFTGPDGLPGPRGPTGLKGDDGPPGRPGPGTPGLRGFDGIKGNPGPPGRDGLPGQPGERGSIGAIGLPGEPGPKGTAGVKGDKGDKGL----SVEGPPGEPGP---PGLRGSPGLKGVRGRDGSNGAPGLNGDIGLPGDPGNSGPPGPP---GLPGKDGTDGNIGEKGFPGLPGPRGPSGENGLPGTRGAQGTPGDPGIPGPPGDTGRAGFPGFKGDKGGKGIQGPPGTTEPGNI------PGPKGMTGNPG---QPGPPGANGVDGIRGFKGDIGLP----GDIGTPGPPGKSGQPGPP--GPPGSPGKKGENGRDGINGINGLRGDIGLPGPPGVDGTDGGSEGPPGQKGSKGNPGR-GLVGPRGPPGAPGMKGLPGFPGIKGSKGVNGADGRKGFKGSSGAKGDQGERGPPGPPGLPGRDGIDGLNGEKGNTGVPGNPGPPGAQGVRGRKGVSGLPGQ--RGPSGDPGPRG----------PQGPRGIAGVPGNPGSPGIPGLPGMPGLKGAKGE---LGLPGTPGSDGTPGAKGDKGNPGFPGVDGRPGEDGPAGEKGDTGLPGTXGAKGATGRPGARGSPGLPGFKGLKGEPGKDGLPGTPGNKGAPGADGFPGLPGXKGNTGIPGLPGLKGEKGY------GLGTXGPKGDRGDAGLPGINGDKGEPGIPGFPGGPGPKGDKGLMGADGREGPRGNPGRDGSKGESGPGLPGVPGPTGRRGPQG-TSDFGFFFTRHSQTDQLPSCPDSTFPLWTGYSLLYVQGNERAHGQDLGSPGSCLRRFSTMPFLFCNIENVCNLASRNDYSFWLSTTAPVPVREENVQRHISRCAVCEARAQVIAVHSQSNALPDCPRDWDPLWQGYSFLMHTSAGNDGSGQPLSSPGSCLEDFRAHPFIECHG-RGTCQYYGSTYSFWLATVDAKNQRVPRPETLKAGTLRERVSRCKVCMRRL >XP_043748401.1 collagen alpha-2(IV) chain [Cervus elaphus] AARPALLLGAVTVGLLAQSVLAGVKKLDVPCGGRDCSQCFPEKGGRGQPGPVGPQGYTGPPGLQGFPGLQGRKGDKGERGAPGTTGPKGDVGPRGVSGYPGANGIPGHPGQGGPRGPPGYDGCNGTMGDAGSAGPQGPGGFLGPPGQGPKGQKGEPYALPRDKYRGEIGEPGLVGMQGPPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDMGLQGPGGIPPKGEKGSGGEPGRIGI---SLKGEEGIMGFSGSRGAPGFDGEKGSPGQKGSRGLDGYQGSDGLPGPKGETGDPGPPGLPAGVRGEPGSPGQPGEPGARGEPGDPGLPGRPGTDEDEKRGLPGEMGPKGYTGERGFPAVYPGPPGTEGKPGLRGPPGRPGPPGPDGFLFGLKGARGSGGFPGSAGFPGARGQKGWKGDAGRGPPGLPGPKGFAGTNGQPGSKGSQGDPGQHGLPGFPGFKGAPGNVGPPGPKGMKGDSTITTKGERGQPGVPGVPGLKGGDGIPGPPGLDGFHGLPGPPGDGIKGPPGDAGQPGAPGTKGLPGERGPPGLGLPGPKGERGFPGDAGLPGPPGFRGPPGLPGAPGQIDCDSGVKRPIGADGQVGGPKGSPGQPGLPGPPGAKGLRGVPGFSGADGVPGLKGLPGDPGREGFPGPPGFMGPRGSKGAGPPGLDGLPGTSGLPGPVGPPGDRGLPGEVLGAQPGPRGDSGLPGRPGLKGPPGERGAPGFRGSQGMPGMPGQKGQPGSPGLSGQPGLPGPPGLHGFPGAPGREGPLGPLGAPGFEGLPGDRGEPGDTGVPGPVGMKGESGDRGDPGQQGARGHPGSPGFKGVSGMPGAPGLKGARGSPGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPIILPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGIPGLPGRPGHVKGVKGDIGIPGVPGSPGFPGVGSPGIMGFQGFTGSRGDKGAPGTAGLFGEVGPTGDFGDIGDTIDLPGSPGLKGERGTTGAPGLKGFFGQKGAEGDVGFPGITGLAGVQGPPGFKGQTGFPGLTGLQGPQGDPGRAGAPGTKGDSGWPGNPGLPGLPGLRGIGGLHGLPGSKGFPGSPGADLHGDLGFPGPAGDRGDPGEANTLPGPTGAPGQKGERGVPGGRGPMGSPGLQGFPGITPPSNISGSPGDIGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGTKGWVGDPGPQGRPGVFGLPGEKGPRGEPGFMGNIGPTGSVGDRGPKGPKGDRGLPGAPGPVGAPGIAGIPQRIVVERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGMSANPGFRGDQGPMGLQGPVGFGEPGRPGSPGLPGMPGRSISIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYASRNDKSYWLSTTAPLPVAEEDIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYTNKYSFWLTTIEQTFQGTPSADTLKAGLIRTHISRCQVCMKNL >XP_043334259.1 collagen alpha-2(IV) chain [Cervus canadensis] AARPALLLGAVTVGLLAQSVLAGVKKLDVPCGGRDCSQCFPEKGGRGQPGPVGPQGYTGPPGLQGFPGLQGRKGDKGERGAPGTTGPKGDVGPRGVSGYPGANGIPGHPGQGGPRGPPGYDGCNGTMGDAGSAGPQGPGGFLGPPGQGPKGQKGEPYALPRDKYRGEIGEPGLVGMQGPPGRPGPVGQMGPVGAPGRPGPPGPPGPKGQPGNRGLGFYGEKGEKGDMGLQGPGGIPPKGEKGSGGEPGRIGI---SLKGEEGIMGFSGSRGAPGFDGEKGSPGQKGSRGLDGYQGSDGLPGPKGETGDPGPPGLPAGVRGEPGSPGQPGEPGARGEPGDPGLPGRPGTDEDEKRGLPGEMGPKGYTGERGFPAVYPGPPGTDGKPGLRGPPGRPGPPGPDGFLFGLKGARGSGGFPGSAGFPGARGQKGWKGDAGRGPPGLPGPKGFAGTNGQPGSKGSQGDPGQHGLPGFPGFKGAPGNVGPPGPKGMKGDSTITTKGERGQPGVPGVPGLKGGDGIPGPPGLDGFHGLPGPPGDGIKGPPGDAGQPGAPGTKGLPGERGPPGLGLPGPKGERGFPGDAGLPGPPGFRGPPGLPGAPGQIDCDSGVKRPIGADGQVGGPKGSPGQPGLPGPPGAKGLRGVPGFSGADGVPGLKGLPGDPGREGFPGPPGFMGPRGSKGAGPPGLDGLPGTSGLPGPVGPPGDRGLPGEVLGAQPGPRGDSGLPGRPGLKGPPGERGAPGFRGSQGMPGMPGQKGQPGSPGLSGQPGLPGPPGLHGFPGAPGREGPLGPLGAPGFEGLPGDRGEPGDTGVPGPVGMKGESGDRGDPGQQGARGHPGSPGFKGVSGMPGAPGLKGARGSPGMDGFEGMLGLKGRPGLPGIKGEAGFFGIPGLKGLAGEPGVKGSRGDPGPPGPPPIILPG-MKDIKGEKGDEGPMGLKGYLGLKGLPGMPGIPGLSGIPGLPGRPGHVKGVKGDIGIPGVPGSPGFPGVGSPGIMGFQGFTGSRGDKGAPGTAGLFGEVGPTGDFGDIGDTIDLPGSPGLKGERGTTGAPGLKGFFGQKGAEGDVGFPGITGLAGVQGPPGFKGQTGFPGLTGLQGPQGDPGRAGAPGTKGDSGWPGNPGLPGLPGLRGIGGLHGLPGSKGFPGSPGADLHGDLGFPGPAGDRGDPGEANTLPGPTGAPGQKGERGVPGGRGPMGSPGLQGFPGITPPSNISGSPGDVGAPGIFGLEGYRGPPGPPGPAALPGSKGDEGSPGTPGNPGTKGWVGDPGPQGRPGVFGLPGEKGPRGEPGFMGNIGPTGSVGDRGPKGPKGDRGLPGAPGPVGAPGIAGIPQRIVVERGPVGPQGRRGPPGAQGEMGPQGPPGEPGFRGAQGKAGPQGRGGMSANPGFRGDQGPMGLQGPVGFGEPGRPGSPGLPGMPGRSISIGYLLVKHSQTDKEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDICYYASRNDKSYWLSTTAPLPVAEEDIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYTNKYSFWLTTIEQTFQGTPSADTLKAGLIRTHISRCQVCMKNL >KYO41305.1 hypothetical protein Y1Q_0006157 [Alligator mississippiensis] CHHVQVLLLLMLTTLLTGRVQAGGKTYTGPCAGRDCSQCFPEKGSRGQPGPLGPQGFPGPPGLIGIPGLEGPKGHKGERGQPGITGPKGDQGLRGVTGFPGADGVPGHPGQPGSRGKPGHDGCNGTTGDPGEQGILGPPGQFGFIGQGPKGQKGEPYVFPADKYRGEMGKPGIKGFQGPRGEPGLVGFIGPKGRPGKPGPPGLPGPQGEKGNRGLGFYGKKGEKGEIGSEGPPGLPSKGQQGMKGEKGEPGISGSAEKGEEGIMGFPGQRGLPGINGIPGPVGEAGPPGFYGSPGYDGPKGMKGEQGEKGIPGLPAGVRGDQGVTGFPGPRGDLGEKGNPGIPGRPGTDGLDKRGLPGEMGPKGYKGEPGFSALYPGIPGFPGQPGPKGFPGPAGPKGSLSISFGLKGRRGDPGAAGSRGFPGPRGDKGFKGETGKSSAGLPGPPGFQGPPGEPGRKGEPGDQGQHGIPGFPGAKGFPGETGYPGPRGQKGYSYITTKGSKGDPGDPGLAGVQ------------------------------------------------------------------------------------------------------------------------GSKGAKGIPGDPGLDGLQGLKGFPGDPGQEGLPGPPGFHGPRGERGPGLLGQQGDDGISGKPGLPGPDGPKGVAGEVLGASAGSIGDVGLPGLPGLKGPPGNQGVPGLQGAGGIPGSPGSKGEPGLQGPHGLIGLPGEPGSHGFPGIPGHQGPAGRGGITGNIGSPGARGDHGEQGFPGPVGMKGLSGDKGELGIPGVQGIPGKTGLPGIDGMHGLQGYKGAKGSPGIEGFKGMTGNRGFQGHKGVKGEIGFFGISGLKGEQGNPGSKGDRGEQGEPGKPPKIDPSMLVEVKGEKGDSGQTGLKGDSGFKGLKGMPGLPGEPGFPGFPGQPSHVSGAKGDIGSKGVTGSLGYPGQGSPGIRGFPGSTGIRGEKGTEGFTGLYGESGLPGESGTPGDTINLPGIPGLKGEVGTPGSSGVRGSPGEKGQRGDPGFSGIEGLKGSQGLPGIKGQSGFPGLVGPPGQQGDPGAPGLPGEKGTQGWPGFAGPTGLPGLRGISGLDGLPGTKGLQGSPGLDDYGPSGFPGGPGDKGQVGDPSTLEGARGGPGQKGERGNQGERGPTGSPGLDGIPGPPGVSNISGIRGDIGSPGLYGVPGYKGEQGRRGIPSPPGSKGEIGQIGVVGEDGPKGTRGDPGLTGKPGILGSFGAKGQKGEQGVMGPVGTLGISGDTGPAGPKGNRGVTGIQGPPGSPGLTPLPSKTLAEVGAPGPHGQRGPQGIPGEIGPQGPLGDSGFRGAPGKQGLQGRSGIPALPGFRGDQGPQGHQGPSGSGIPGRPGSPGLPGMPGRSVNIGYLLVKHSQSDQEPMCPIGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYANRNDKSYWLSTTAPLPVAEEEIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPEGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGARGTCHYYANKYSFWLTTIEEQFQSTPSADTLKAGLIRTHISRCQVCMKNL >XP_018105335.1 collagen alpha-2(IV) chain isoform X1 [Xenopus laevis] KRCATCVLLVVLVTVFAGNAHAGGKSYTGPCGGRDCSQCLPEKGSRGQPGPLGAQGTPGPPGLIGIAGLQGHKGDKGERGFTGVTGPSGDKGHRGVTGFAGADGVPGHTGQGGPRGKPGHDGCNGTKGDGGDGGSHGPRGPPGIPGFGAKGQKGDPFHVSKNRLKGDPGEPGFNGIQGPRGFPGIAGFIGPQGNRGPRGPPGPPGPQGSQGNRGLGYYGEKGETGDPGPPGEQSGPGKGATGDQGEKGIPGDEGQGEKGEEGITGFPGQRGLPGIDGARGASGEIGFPGTNGVPGLPGQNGKKGDHGERGPQGPVTGYEGDIGFPGQDGLYGDEGDLGDPGFPGQKGFGPTGDTGLKGQRGPKGYPGDPGLPAFQPGPPGIDGDPGKEGPPGKPGYPG---GRIGMKGLPGPPGRDGHRGFPGSRGFKGNKGEQGKGPAGEPGPVGFPGLQGLSGRKGETGDRGVPGLPGTPGTVGPAGPAGLPGPAGEKGDKFATEKGSKGVQGDPGVPGIPGHVGYPGRNGKDGIPGFPGPPGDGVKGLPGHAGFPGQPGIAGARGETGFPGPGFPGPKGMRGDSGDRGVSGFPGIPGLPGPQG-----DCETDEENKIGKEGTPPAPTGSPGPPGLPGYNGLRGQKGFPGPQGFDGVFGLKGVKGDPGNDSLPGPPGFPGQRGDRGNGFPGQPGAPGLSGKPGLKGVQGEKGVAGDRLGAPPGEQGDTGLPGLQGLKGKQGDQGIPGLQGNFGTPGTPGNKGIQGSVGAPGAPGIPGPAALFGFPGIPGNPGMLGPQGSMGPPGPPGPRGDEGEKGPPGPVGMKGLPGEPGDQGFVGVRGKQGAPGIPGLVGMHGLPGVKGIKGSPGMEGFHGMKGVKGRPAWRGIKGPSGNIGFPGIKGREGIPGAKGDRGERGPPGESPQMLPEIMLLVKGEKGDQGVPGFKGTTGPKGSKGMPGNPGQPGTPGLPGIPSFEFGDKGEIGSPGPVGHPGIPGEGPRGIIGFPGFTGPRGTPGFSGLPGVPGERGSYGDTGERGDTIDLPGEEGVKGQVGIPGLPGQHGIPGEKGIKGDQGVQGIEGMKGEPGQPGERGFPGQQGLVGLPGSQGSPGLPGVHGEKGSAGFPGFPGQHGFPGTRGIAGLDGLPGTKGIQGQPGAEITGLKGFKGLSGERGQPGEASSIVGTPGPAGLKGTKGDQGLPGLIGITGTVGVRGLPGFSNRTGTPGDVGFPGPPGLPGFPGPMGIPGLPSKPGVKGEIGELGSQGDYGAKGIPGDQGKLGATGVAGMPGVKGWKGNAGFHGVVGESGHPGDQGPKGYKGDKGEHGFKGPPGQPGPVSEPPLATAEHGSPGPQGIIGPEGVRGDIGPKGVVGSPGAPGQTGKEGLPGIPGWSAPPGNRGELGLMGQRGLDGLGDSGVPGRAGLPGMPGRSVNIGYLLVKHSQTDEEPMCPVGMAQLWTGYSLLYFEGQEKAHNQDLGLAGSCLQRFSTMPFLYCNPGDVCYYANRNDKSYWLSTTVPLPVVEEEIRPYISRCSVCEAPAVAIAVHSQDVSIPHCPDGWRSLWIGYSFLMHTAAGDEGGGQSLASPGSCLEDFRATPFIECNGGRGTCHYFANKYSFWLTTIDQPFQSSPSADTLKAGLIQTHISRCQVCMKNL
PhyML tree of selected proteins (ACK77661_1_RE33133p__Drosophila_melanogaster_:1.816439,(XP_006563187_2_collagen_alpha_5_IV__chain__Apis_mellifera_:2.01618982,(NP_001022662_2_Collagen_alpha_1_IV__chain__Caenorhabditis_elegans_:1.3968474,(NP_999631_1_3_alpha_procollagen_precursor__Strongylocentrotus_purpuratus_:1.39140582,XP_031568877_1_collagen_alpha_2_IV__chain_like__Actinia_tenebrosa_:1.28933157):0.14516895):0.16762502):0.13402914,(CAE1304334_1_COL4A__Sepia_pharaonis_:1.21056512,((XP_038051105_1_collagen_alpha_2_IV__chain_like_isoform_X1__Patiria_miniata_:2.00232682,XP_039251035_1_collagen_alpha_2_IV__chain_like__Styela_clava_:1.45566218):0.25282304,((tr_A0A0H2UKP2_A0A0H2UKP2_DANRE_Collagen__type_IV__alpha_2_OS_Danio_rerio_OX_7955_GN_col4a2_PE_1_SV_2:0.55023088,(XP_011488241_1_collagen_alpha_2_IV__chain_isoform_X1__Oryzias_latipes_:0.28874332,(XP_015821737_1_PREDICTED__collagen_alpha_2_IV__chain_isoform_X1__Nothobranchius_furzeri_:0.29140004,XP_030285421_1_collagen_alpha_2_IV__chain_isoform_X1__Sparus_aurata_:0.24502127):0.05648933):0.24495937):0.47608294,((((XP_006017292_1_collagen_alpha_2_IV__chain__Alligator_sinensis_:0.01116278,KYO41305_1_hypothetical_protein_Y1Q_0006157__Alligator_mississippiensis_:0.00360241):0.3145996,(XP_021152299_1_collagen_alpha_2_IV__chain__Columba_livia_:0.09356658,(XP_010726857_1_collagen_alpha_2_IV__chain__Meleagris_gallopavo_:0.02623368,NP_001155862_1_collagen_alpha_2_IV__chain_precursor__Gallus_gallus_:0.01729175):0.04815332):0.20700136):0.13994891,((XP_038951185_1_collagen_alpha_2_IV__chain__Rattus_norvegicus_:0.02333332,NP_034062_3_collagen_alpha_2_IV__chain_precursor__Mus_musculus_:0.03342254):0.06543475,((XP_024086739_1_collagen_alpha_2_IV__chain__Pongo_abelii_:0.00697139,(sp_P08572_CO4A2_HUMAN_Collagen_alpha_2_IV__chain_OS_Homo_sapiens_OX_9606_GN_COL4A2_PE_1_SV_4:0.00727118,(XP_004054779_3_collagen_alpha_2_IV__chain__Gorilla_gorilla_gorilla_:0.00611364,(XP_034792866_1_collagen_alpha_2_IV__chain__Pan_paniscus_:0.00134292,XP_024204109_1_collagen_alpha_2_IV__chain_isoform_X1__Pan_troglodytes_:0.00000002):0.00068077):0.00013785):0.00584777):0.09027273,(XP_008258402_1_PREDICTED__collagen_alpha_2_IV__chain__Oryctolagus_cuniculus_:0.11817075,((XP_023108926_1_collagen_alpha_2_IV__chain__Felis_catus_:0.044882,XP_038287383_1_collagen_alpha_2_IV__chain_isoform_X1__Canis_lupus_familiaris_:0.03356583):0.0254567,(XP_020921567_1_collagen_alpha_2_IV__chain__Sus_scrofa_:0.0490787,((XP_020769119_1_collagen_alpha_2_IV__chain__Odocoileus_virginianus_texanus_:0.01061154,(XP_043748401_1_collagen_alpha_2_IV__chain__Cervus_elaphus_:0.00132579,XP_043334259_1_collagen_alpha_2_IV__chain__Cervus_canadensis_:0.00000001):0.0105227):0.02153839,(XP_024855939_1_collagen_alpha_2_IV__chain__Bos_taurus_:0.02535401,(XP_017911852_1_PREDICTED__collagen_alpha_2_IV__chain__Capra_hircus_:0.00487747,XP_027829588_1_collagen_alpha_2_IV__chain_isoform_X1__Ovis_aries_:0.00526962):0.01305097):0.01357674):0.06448266):0.03347706):0.03055199):0.00950195):0.0336411):0.43369118):0.13088624,(XP_040192142_1_collagen_alpha_2_IV__chain__Rana_temporaria_:0.50765914,XP_018105335_1_collagen_alpha_2_IV__chain_isoform_X1__Xenopus_laevis_:0.3801847):0.27917497):0.21115404):0.66894756):0.18669518):0.14697888);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)