PB0146

DATABASE

Click here to access PB0146 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0146	P35443	Thrombospondin-4	THBS4	TSP-4, TSP4	Homo_sapiens	Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner (By similarity).

Domains

Gene Ontology

PF02412 (6_TSP_3) PF05735 (TSP_C) PF07645 (2_EGF_CA) PF11598 (COMP)

GO:0005178 (enables) integrin binding GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0008083 (enables) growth factor activity GO:0008201 (enables) heparin binding GO:0001938 (involved in) positive regulation of endothelial cell proliferation GO:0006986 (involved in) response to unfolded protein GO:0007155 (involved in) cell adhesion GO:0007165 (involved in) signal transduction GO:0016525 (involved in) negative regulation of angiogenesis GO:0034103 (involved in) regulation of tissue remodeling GO:0034976 (involved in) response to endoplasmic reticulum stress GO:0048266 (involved in) behavioral response to pain GO:0048771 (involved in) tissue remodeling GO:0050731 (involved in) positive regulation of peptidyl-tyrosine phosphorylation GO:0051451 (involved in) myoblast migration GO:0051781 (involved in) positive regulation of cell division GO:0071603 (involved in) endothelial cell-cell adhesion GO:0090023 (involved in) positive regulation of neutrophil chemotaxis GO:0005576 (located in) extracellular region GO:0005604 (located in) basement membrane GO:0005615 (located in) extracellular space GO:0005783 (located in) endoplasmic reticulum GO:0016529 (located in) sarcoplasmic reticulum GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P35443|TSP4_HUMAN Thrombospondin-4 OS=Homo sapiens OX=9606 GN=THBS4 PE=1 SV=2 MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYV ISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLA DGRRHRILLRLSNLQRGAGSLELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQ DFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDL LRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQ CTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGP MVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSAR NCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFG DACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGD ACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIG DECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCP ENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVD FEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYE GSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFD N >tr|F1R1P9|F1R1P9_DANRE Thrombospondin-4-B OS=Danio rerio OX=7955 GN=thbs4b PE=3 SV=1 MAGTMHLLTAVSLILMLSSANAESIVYNLLTSPDCLPDLLHGGLAEQGVTELYILTTFRI QPGTGNTIFSLYNPRDNSKYFEFSVFGKANKAILRYLRRDGRMSAVTFNKLNLADGEKHR LLFHLKGLEVGHPGGFPHSQGALPVPGVELHLDCRLVETLRDLPAVFNGLNNHQAVELKT MQGKAQEGLEELKLAYGDSVENVASLQDCHTQSDSVQALGLNTKQLTTQMLELTKVINEL KDVLIQQVKETSFLRNTISECQACGLSGAEVVKPKCAPGVCFRDDMCIETAEGVECGPCP DGYTGDGYSCDDVDECQFNPCFPGVRCVNMAPGFRCEACPLGFTGKPLEGVGVAYAQTHK QVCDDIDECKGPDNGGCTANSICVNSVGSYQCGRCKTGFTGDQIRGCKPEKSCGNRLQNP CDPNAQCTEERDGTITCQCGIGWAGNGYLCGKDTDIDGYPDERLRCRDPTCRKDNCVTVP NSGQEDADGDGKGDACDPDADGDGILNEQDNCWLTPNINQQNSDKDSHGDACDNCVRVDN PDQRDTDSDGLGDACDDDMDGDGLKNFLDNCQRVKNRDQLDRDGDGVGDACDSCPDIPNP NQSDIDNDLVGDSCDTNQDSDGDGHQDSKDNCPMVINSSQLDTDKDGIGDECDDDDDNDG IPDSLPPGPDNCRLVPNPEQIDDNNDGVGDICESDFDQDKVIDRIDNCPENAEITLTDFR AYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFSGVDFEGTFHVNTVT DDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRN SLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYLQHRPQVGYIRVRFYEGTELVADSGVT IDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFSTQHGMDPL
Selected proteins from model organisms >sp|P35443|TSP4_HUMAN Thrombospondin-4 OS=Homo sapiens OX=9606 GN=THBS4 PE=1 SV=2 MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYV ISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLA DGRRHRILLRLSNLQRGAGSLELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQ DFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDL LRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQ CTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGP MVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSAR NCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFG DACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGD ACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIG DECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCP ENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVD FEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYE GSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFD N >tr|F1R1P9|F1R1P9_DANRE Thrombospondin-4-B OS=Danio rerio OX=7955 GN=thbs4b PE=3 SV=1 MAGTMHLLTAVSLILMLSSANAESIVYNLLTSPDCLPDLLHGGLAEQGVTELYILTTFRI QPGTGNTIFSLYNPRDNSKYFEFSVFGKANKAILRYLRRDGRMSAVTFNKLNLADGEKHR LLFHLKGLEVGHPGGFPHSQGALPVPGVELHLDCRLVETLRDLPAVFNGLNNHQAVELKT MQGKAQEGLEELKLAYGDSVENVASLQDCHTQSDSVQALGLNTKQLTTQMLELTKVINEL KDVLIQQVKETSFLRNTISECQACGLSGAEVVKPKCAPGVCFRDDMCIETAEGVECGPCP DGYTGDGYSCDDVDECQFNPCFPGVRCVNMAPGFRCEACPLGFTGKPLEGVGVAYAQTHK QVCDDIDECKGPDNGGCTANSICVNSVGSYQCGRCKTGFTGDQIRGCKPEKSCGNRLQNP CDPNAQCTEERDGTITCQCGIGWAGNGYLCGKDTDIDGYPDERLRCRDPTCRKDNCVTVP NSGQEDADGDGKGDACDPDADGDGILNEQDNCWLTPNINQQNSDKDSHGDACDNCVRVDN PDQRDTDSDGLGDACDDDMDGDGLKNFLDNCQRVKNRDQLDRDGDGVGDACDSCPDIPNP NQSDIDNDLVGDSCDTNQDSDGDGHQDSKDNCPMVINSSQLDTDKDGIGDECDDDDDNDG IPDSLPPGPDNCRLVPNPEQIDDNNDGVGDICESDFDQDKVIDRIDNCPENAEITLTDFR AYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFSGVDFEGTFHVNTVT DDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRN SLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYLQHRPQVGYIRVRFYEGTELVADSGVT IDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFSTQHGMDPL >NP_035712.1 thrombospondin-4 precursor [Mus musculus] MPAPRAAAAAFLLLHLVLQPWQRTSAQATPQVFDLLPSSSQRLNPSALQPVLTDPTLHEVYLISTFKLQS KSSATIFGLYSSSDNSKYFEFTVMGRLNKAILRYLKNDGKIHLVVFNNLQLADGRRHRVLLRLSNLQRGD GSVELYLDCAQADSVRNLPRAFSGLTQNPESIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQS EPLAATSTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVPIA PPAPPTRPTRHCDSSPCFRGVRCTDTRDGFQCGPCPDGYTGNGITCSDVDECKYHPCYPGVRCVNLAPGF RCDACPVGFTGPMVQGVGINFAKTNKQVCTDVDECQNGACVLNSICINTLGSYRCGPCKPGYTGDQTRGC KTERSCRNPEQNPCSVHAQCIEERQGDVTCVCGVGWAGDGYVCGKDVDIDSYPDEELPCSARNCKKDNCK YVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNIDQRNSDKDIFGDACDNCRMVLNNDQKDTD GDGRGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDDVGDACDSCPDVSNPNQSDVDNDLVGDSCDTN QDSDGDGHQDSTDNCPTVINSSQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNNDG VGDICEADFDQDQVIDHIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPG LAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKA VKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADS GVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQSFDRLDN >NP_058829.1 thrombospondin-4 precursor [Rattus norvegicus] MLAPRAAAFLLLHLVLQPWQRAGAQATPQVFDLLPSSSQRLNPAALQPVLTDPTLHELYVISTFKLQSKS SATIFGLYSSSDNSKYFEFTVMGRLNKAILRYLKDDGKIHLVVFNNLQLADGRRHRILLRLSNLQRGAGS VELYLDCVQVDSVNNLPRAFSGLTQNPQAIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEP LAATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVPIAPP APPTRPTRRCDSSPCFRGVRCTDTRDGFQCGPCPDGYTGNGITCSDVDECKYHPCYPGVRCTNLAPGFRC DACPVGFTGPMVQGVGINFAKTNKQVCTDVDECRNGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCRT ERSCRNPEQNPCSVHAQCIEERQGDVTCVCGVGWAGDGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYV PNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNTDKDIFGDACDNCRGVLNNDQKDTDGD GKGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQD SDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNNDGVG DICEADFDQDKVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLA VGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGV TIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQIQTFDRLDN >NP_001308478.1 thrombospondin-4 precursor [Gallus gallus] MGCERGAALLLLPLALQLCPGRAAPPAPRVIDLLPYANKRVVTSFLQQALGDPTLNEVFLLSVFKLQPKS TTTIFDLYSPADDRQYFEFTVMGRMNKVVLRYLKNDGRLNSVIFSNVHLADGKPHAVILWLSGLQQELCT IELYLDCLQVGAIQDLPKAFSTLLERSAAVELRTFLKKPEDTLDELKLVTGGTLAQARDLQDCFLQQIES APQYTGDFNRQLMNQMVQMNQILGEVKDLLKQQVKETTFLRNTIAECQACGLGTANFPTPLPRHTKPKCE ASSCFRGVRCMETAEGIQCGPCPEGLTGNGVTCSDVDECRYSPCFPGVRCVNTAPGFRCETCPPGYTGQT LQGVGLSYAKNNKQVCLDIDECQNGGHGVCVPNSQCINTLGSYRCGQCKSGYTGDQIRGCQAERSCRSRA LNPCSVHARCIEERRGEVTCICGIGWAGDGYICGKDIDIDGYPNEELSCPSESCRKDNCKFVPNSGQEDA DDDGIGDACDEDADGDGIPNEQDNCVLTPNVNQRNSDEDIFGDACDNCRSVLNNDQRDTDGDGKGDACDD DMDGDGIKNLLDNCQRIPNQDQEDKDNDGVGDACDSCPTVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQD STDNCPTIINSSQLDTDKDGLGDECDEDDDNDGIPDLLPPGPDNCRLVPNPGQEDDNGDGVGDVCESDFD QDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNG VDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEH LRNSLWHTGDTSDQVRLLWKDPRNVGWKDKVSYRWFLQHRPQIGYIRARFYEGSDLVADSGVTIDTTMRG GRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQAQQFGVGDI >XP_016808573.2 thrombospondin-4 [Pan troglodytes] MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYVISTFKLQTKS SATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLADGRRHRILLRLSNLQRGAGS LELYLDCIQVDSIHNLPRAFAGPSQKPETIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEP LAATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPP APPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVRCINLSPGFRC DACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYV PNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGD GRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQD SDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVG DICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLA VGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGV TIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFDN >XP_038327488.1 thrombospondin-4 [Canis lupus familiaris] MPGPRGAALLLLHLVLQPWLRAGAQGPPQVFDLLPSSSQRLNPAVLKPILTDPTLNEVYVISTFKLHTKS SATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKIHLVVFNNLQLADGRRHRVLLRLTNLQRGAGS VELYLDCTQVDSVHNLPRAFSGSSQSPDSIELRTFQRKAQDFLEELKLVVRGSLFQVASLQDCFLQQSEP LATTSTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVPPAPP APATSPTPPVRRCDSNSCFRGVRCTDTRDGFQCGPCPEGYTGNGITCSDIDECKYHPCYPGVRCVNLAPG FRCEACPVGFTGPVVQGIGISFAKSNKQVCTDIDECRNGACVLNSICINTLGSYRCGPCKPGYTGDQTRG CRTERSCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNC RYVPNSGQEDADGDGVGDACDEDADGDGILNEQDNCVLTHNVDQRNSDKDIFGDACDNCRNILNNDQKDT DGDGKGDACDDDMDGDGIKNILDNCPRVPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDT NQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNRD GVGDICETDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDP GLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLK AVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVAD SGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDS >NP_001029900.1 thrombospondin-4 precursor [Bos taurus] MLAPRGATFLLLHLALQPWLGAGAQATPQVFDLLPSASQRLNPSVLQPILTDPTLNELYVISTFKLQSKS SATIFGLYSSADHSKYFEFTVMGRLNKAILRYLKNDGRIHLVVFNNLQLADGRRHRLLLRLTNLHRGAGS VELFLDCTRVDSIHNLPRAFSGLAQSPEAVELRTFQRKAHDSLEELKLVVRGSLIQVASLQDCFLQQSEP LATTNTGDFNRQFLGQMSQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLMPVVPA ASPTPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGNGIVCSDVDECRYHPCYPGVRCVNLAPGFRC DACPVGFTGPMMQGVGISFAKTNKQVCTDIDECRNGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKM ERNCRDPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYV PNSGQEDADRDGIGDACDDDADGDGILNEQDNCVLTHNVDQRNSDKDIFGDACDNCRNVLNNDQKDTDGD GKGDACDDDMDGDGIKNILDNCQKVPNSDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQD SDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVG DICEADFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLA VGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGV TIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDK >XP_008260094.1 PREDICTED: thrombospondin-4 [Oryctolagus cuniculus] MRAPRGAALLPLHLALLHLALQPWPGAGAQATPQVFDLLPPSGERLSPGVLQPLLADPALHDLYVLSTFK LQTKSSAPIFGLYSTADNSRYFEFTVMGRLNKAILRYMKSDGKIHLVVFNNLQLADGRRHRLLLRLSNLQ RGAGSVELYVDCTQVDSVHNLPRAFAALSQSPESFELKTLQRKAQDFLEELKLVVRGSLFQVASLQDCFL QQSEPLAAAGSGDFNRQFLGQMAQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLV PPAPPAPPTRPPRRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGSGITCSDVDECKYHPCYPGVRCVNL APGFRCEACPVGFTGPTVQGAGISFATSNKQVCTDIDECANGACTPHSVCTNSVGSYRCGPCKPGYTGDQ TRGCKPERSCRNPELNPCSPNAQCIQERQGDVTCVCGVGWAGDGYVCGRDVDIDSYPDEELPCSARNCKK DNCKYVPNSGQEDADGDGLGDACDEDADGDSILNEQDNCVLTPNTDQRNSDKDIYGDACDNCRTVLNNDQ KDTDGDGRGDACDDDMDGDGIKNILDNCPRVPNRDQRDKDGDGVGDACDSCPDISNPNQSDVDNDLVGDS CDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDS NSDGVGDICETDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMN SDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGI QLKAVKSQTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSEL VADSGVTIDTTMRGGRLGVFCFSQENIIWFQPQVPLQRHHPRGLPGVPDPELRPPGELGRPGRSSARGPA PAPPLAAAQPPGLALTCPGARRRLLRAWQ >XP_024103393.1 thrombospondin-4 [Pongo abelii] MGHLRRRPGPRPRFNARPGDLQAGPTPPSPPASRGAGRANMLAPRGAAVLLLHLVLQPWLAAGAQATPQV FDLLPSSSQRLNPGALLPVLTDPALNDLYVISTFKLQTKSSATIFGLYSSTDNTKYFEFTVMGRLNKAIL RYLKNDGKVHLVVFNNLQLADGRRHRILLRLSNLQRGAGSLELYLDCIQVDSIHSLPRAFAGPSQKPETI ELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLPATGTGDFNRQFLGQMTQLNQLLGEVKDL LRQQVKETSFLRNTIAECQACGPLKFQSPTPSSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQ CGPCPEGYTGNGITCIDVDECKYHPCYPGVRCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTD IDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCV CGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNE QDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRD QRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGI GDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTD FRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFI FGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKD SRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYR CNDTIPEDFQEFQTQNFDRFDN >XP_020940149.1 LOW QUALITY PROTEIN: thrombospondin-4 [Sus scrofa] MLATRGAALLLLHLALQPWLAAGAQATPQVFDLLPSASQRLNPSVLQPILSDPTLNELYVISTFKLQTKS SATIFGLYSSADNSKYFEFTVMGRLNKAILRYLKNDGKIHLVVFNNLQLADGRRHRLLLRLTNLHRGAGS VELYLDCTQVDSIHNLPRAFAGLSQSPGSVELRTFQRKAQDSLEELKLVVRGSLFQAASLQDCFLQQSEP LAATNTGDFNRQFLGQMSQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVAPAPP ASPTPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGNGVTCSDVDECRYHPCYPGVRCVNLAPGFRC DACPVGFTGPTVQGVGINFAKTNKQVCTDIDECRNGACVLNSICVNTLGSYRCGPCKPGYIXDQMRGCKM ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYV PNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNMDQRNSDKDIYGDACDNCRNVLNNDQRDTDGD GKGDACDDDMDGDGIKNILDNCPKVANRNQQDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQD SDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPGQEDSNSDGVG DICETDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLA VGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGV TIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDN >XP_019465735.1 thrombospondin-4 [Meleagris gallopavo] MRVIDLLSYANKREVTSFLQQALGDPTLNEVFLLSAFKLQPKSTATVFGLYSPADDKQYFEFTVMGRMNK VVLRYLKNDGRLNSVIFSNVHLADGKPHAVILWLSGLQQEFCTIELYLDCLQVGAIQDLPKAFSAQLERS AAVELRTFLKKPEDILDELKLVTGGTLAQARNLQDCFLQQIESAPQYTGKASNQFIQILVQKSCGGEYSS FCIKGLGMVNFPTPLPRRSKPKCETSSCFRGVRCMETAEGIQCGPCPDGFTGNGVTCSDIDECHYSPCFP GVRCVNTAPGFRCETCPPGYTGQTLQGVGLSYAKNNKQVCLDIDECQNGGHGVCVPNSHCINTLGSYRCG QCKSGYKGDQIRGCQAERSCRSRALNPCSVHARCIEERRGEVTCICGIGWAGDGYICGKDVDIDGYPNEE LSCPAESCRKDNCKFVPNSGQEDADDDGIGDACDEDADGDGIPNEQDNCVLTPNVNQRNSDEDIFGDACD NCRSVLNNDQRDTDGDGKGDACDDDMDGDGIKNLLDNCQRIPNQDQEDKDNDGVGDACDSCPTVSNPNQS DVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTIINSSQLDTDKDGLGDECDEDDDNDGIPDLLPPGPDNCR LVPNPGQEDDNGDGVGDVCESDFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLN QGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQAT PFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDPRNVGWKDKVSYRWFLQHRPQIGYI RARFYEGSDLVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQAQQFGVGDI >XP_008974044.2 thrombospondin-4 isoform X1 [Pan paniscus] MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYVISTFKLQTKS SATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLADGRRHRILLRLSNLQRGAGS LELYLDCIQVDSIHNLPRAFAGPSQKPETIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEP LAATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPP APPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVRCINLSPGFRC DACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYV PNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGD GRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQD SDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVG DICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLA VGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGV TIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFDN >XP_003981157.1 thrombospondin-4 [Felis catus] MLAPRGAAFLLLHLALQPWLGAGAQATPQVFDLLPSSSQRLNPAVLQPILTDPTLNEVYVISTFKLHSKS SSTILGLYSSVDGSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLHLADGRRHRVLLRLTNLRRGTGS VELYMDCTQVDSVHNLPRAFSGSSQSPESIELRTFQRKAQDSLEELKLVVRGSLFQVASLQDCFLQQSEP LATTSTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVPPASP APTTSSTPPVRRCDSNSCFRGVRCTDTRDGFQCGPCPEGYTGNGITCSDIDECKYHPCYPGVRCVNLAPG FRCDACPMGFTGPMVQGVGISFAKSNKQVCTDIDECQNGACVLNSICINTLGSYRCGPCKPGYTGDQTTG CKTERSCRNPELNPCSVNAQCIEERQGDVTCVCGIGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNC KYVPNSGQEDADRDGIGDACDDDADGDGILNEQDNCVLTHNVDQRNSDKDIFGDACDNCRNVLNNDQKDT DGDGKGDACDDDMDGDGIKNILDNCPKVPNRDQRDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDT NQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDVVPPGPDNCRLVPNPAQEDSNSD GVGDICETDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDP GLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLK AVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVAD SGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDN >XP_027827293.1 thrombospondin-4 [Ovis aries] MLAPRGAAFLLLHLALQPWLGAGAQAAPQVFDLLPSASQRLNPSVLQPILTDPTLNELYVISTFKLQSKS SATIFGLYSSADHSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLQLADGRRHRLLLRLTNLHRGAGS VELFLDCTRVDSIHNLPRAFSGLAQSPEAVELRTFQRKAHDSLEELKLVVRGSLIQVASLQDCFLQQSEP LATTNTGDFNRQFLGQMSQLNQLLGEVKDLLRQQVKETTFLRNTIAECQACGPLSFQSPTPNTLIPVVPA ASPTPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGNGIACSDVDECKYHPCYPGVRCVNLAPGFRC DACPVGFTGPMLQGVGINFAKTNKQVCTDVDECRNGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKM ERNCRDPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYV PNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNSDKDIFGDACDNCRNVLNNDQKDTDGD GRGDACDDDMDGDGIKNILDNCQKVPNSDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQD SDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVG DICEADFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLA VGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGV TIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDK >XP_004058683.1 thrombospondin-4 [Gorilla gorilla gorilla] MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGVLLPVLTDPALNDLYVISTFKLQTKS SATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLADGRRHRILLRLSNLQRGAGS LELYLDCIQVDSIHNLPRAFAGPSQKPETIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEP LAATGTGDFNRQFLGQMIQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPP APPTRPPRRCDSNPCFRGVQCTDGRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVRCINLSPGFRC DACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYV PNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGD GRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQD SDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVG DICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLA VGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGV TIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFDN >XP_021147870.1 LOW QUALITY PROTEIN: thrombospondin-4 [Columba livia] MVTNFLQQALGDSTLDDVYLLSTFKLQPKSTATVFGLYSSADNNKYFEFTVMGRMNKVVLRYLKSDGRLN SVIFSNIHLADGKPHAVILWLSGLQQGSSTMELYLDCLQVGAVQDMPKAFSALSLRSSAVELRTFQEKPQ EALDELKLVTGGTLAEVGNLQDCFLQQIEPVSQYTGDFNRQLMGQMMQMNQILGDVKDLLRQQVKETTFL RNTIAECSFCIKGLGTVNFPTQLPRRSKPKCEVNSCFRGVRCMETAEGFQCGPCPEGLTGNGVTCSDIDE CRYSPCFPGVRCVNTAPGFRCETCPPGYTGQTVQGVGLSYAKNNKQICLDIDECQNGGLGLCVPNSHCIN TLGSYRCGQCKPGYTGDQVRGCQAERSCRNRALNPCSVHARCIEEKRGEVTCICGIGWAGDGYICGKDVD IDGYPNEELSCSAENCRKDNCRFVPNSGQEDADGDGIGDACDDDADGDGIPNEQDNCVLAPNVNQRNGDQ DIFGDACDNCRNVLNNDQRDTDGDGKGDACDDDMDGDGIKNLLDNCQRIPNQDQEDMDNDGVGDACDSCP TISNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNCPTIINSSQLDTDKDGLGDECDEDDDNXCRLVPN PGQEDDNGDGVGDICESDFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGME IVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRA VAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDPRNVGWKDKVSYRWFLQHRPQIGYIRARF YEGSDLVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQAQQFGVGDI >XP_017909157.1 PREDICTED: thrombospondin-4 [Capra hircus] MLAPRGAAFLLLHLALQPWLGAGAQAAPQVFDLLPSASQRLNPSVLQPILTDPTLNELYVISTFKLQSKS SATIFGLYSSADHSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLQLADGRRHRLLLRLTNLHRGAGS VELFLDCTRVDSIHNLPRAFSGLAQSPEAVELRTFQRKAHDSLEELKLVVRGSLIQVASLQDCFLQQSEP LATTNTGDFNRQFLGQMSQLNQLLGEVKDLLRQQVKETTFLRNTIAECQACGPLSFQSPTPNTLIPVVPA ASPTPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGNGIACSDVDECKYHPCYPGVRCVNLAPGFRC DACPVGFTGPLLQGVGINFAKTNKQVCADVDECRNGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKM ERNCRDPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYV PNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNSDKDIFGDACDNCRNVLNNDQKDTDGD GRGDACDDDMDGDGIKNILDNCQKVPNSDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQD SDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVG DICEADFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLA VGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGV TIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDK >XP_025057186.1 thrombospondin-4 [Alligator sinensis] MKRSFKNAFGKKGTFHELALPDLTNEKWLLKEAKEALWQVAAARARWPEPPRPAQPPGAQPGPQVFDLLS YPNQRLVRNFLQQAFADSTLNEVYLLSTFKLQPKSTATIFGLYSSLENSKYFEFTVIGRLNRAALRYLRS DGRLNSVIFSNIQLADGKRHAVLLRLSGLHRGSSKVEMYVDCMQVDVIQDLPKAFSGLSQSPEFVELRTL QRKAQDILDELKLVVRGSLSQVGSLQDCFLQQIEPAVQYTGDFNRQLMSQMMQMNQILGDVKDLLRQQVK ETTFLRNTIAECQACGLGPMDFPTSPPRPPKPRCEATSCFRGVRCTETADGFQCGPCPEGFTGNGVTCSD TDECRYNPCFPGVQCVNSVPGFKCEPCPPGYTGQTVQGVGINYAKNNKQVCSDIDECNNGGNELCVPNSH CINTLGSYRCGPCKTGYVGDQIKGCNAEKSCRNRALNPCSIYAQCIEERQGDVSCVCGIGWAGDGYICGK DVDIDGYPNEDLTCSADTCRKDNCRFVPNSGQEDADGDGIGDACDDDADGDGIPNEQDNCVLIPNVNQKN SDQDIFGDACDNCRTVPNNDQKDTDGDGKGDACDDDMDGDGIKNLLDNCQRIPNQDQKDKDNDGVGDACD SCPHISNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGLGDECDDDDDNDGIP DLIPPGPDNCRLVPNPGQEDENTDGVGDICESDFDQDTVIDQIDVCPENAEITLTDFRAYQTVVLDPEGD AQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMW KQTEQTYWQAAPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRW FLQHRPQMGYIRARFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFEEFQA QQFGVGDI >XP_014449911.1 PREDICTED: thrombospondin-4 [Alligator mississippiensis] MSPRGAACLLLQLLLQLWPGRGAQPGPQVFDLLSYPNQRLVRNFLQQALADPTLNEVYLLSTFKLQPKST ATIFGLYSSLENSKYFEFTVIGRLNRAALRYLRSDGRLNSVIFSNIQLADGKRHAVLLRLSGLHRGSSKV EMYVDCMQVDVIQDLPKAFSGLSQSPEFVELRTLQRKAQDILDELKLVVRGSLSQVGSLQDCFLQQIEPE VQYTGDFNRQLMSQMMQMNQILGDVKDLLRQQVKETTFLRNTIAECQACGLGPMDFPTSPPRPLKPRCEA TSCFRGVRCTETADGFQCGPCPEGFTGNGVTCSDTDECRYNPCFPGVQCVNSVPGFRCEPCPPGYTGQTV QGVGINYAKNNKQVCSDIDECNNGGNELCVPNSHCINTLGSYRCGPCKTGYMGDQIKGCNAEKSCRNQAL NPCSIYAQCIEERQGDVSCVCGIGWAGDGYICGKDVDIDGYPNEDLTCSADTCRKDNCRFVPNSGQEDAD GDGIGDACDDDADGDGIPNEQDNCVLIPNVNQKNSDQDIFGDACDNCRTVPNNDQKDTDGDGKGDACDDD MDGDGIKNLLDNCQRIPNQDQKDKDNDGVGDACDSCPHISNPNQSDIDNDLVGDSCDTNQDSDGDGHQDS TDNCPTVINSSQLDTDKDGLGDECDDDDDNDGIPDLIPPGPDNCRLVPNPGQEDENTDGVGDICESDFDQ DTVIDQIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGV DFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQAAPFRAVAEPGIQLKAVKSKTGPGEHL RNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWFLQHRPQMGYIRARFYEGSELVADSGVTIDTTMRGG RLGVFCFSQENIIWSNLKYRCNDTIPEDFEEFQAQQFGVGDI >XP_020725677.1 thrombospondin-4 [Odocoileus virginianus texanus] MLAPRGATVLLLHLALQPWLGAGAQATPQVFDLLPSASQRLNPSVLQPILTDPTLNELYVISTFKLQSKS SATIFGLYSSADHSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLQLADGRRHRLLLRLTNLHRGAGS VELFLDCTRVDSIHNLPRAFSGLAQSPEAVELRTFQRKAHDSLEELKLVVRGSLIQVASLQDCFLQQSEP LATTNTGDFNRQFLGQMSQLNQLLAEVKDLLRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVPAVPA ASPTPAPRRCDSSPCFRGVRCTDTRDGFQCGPCPEGYTGNGVACSDVDECKYHPCYPGVRCVNLAPGFRC DACPVGFTGPMMQGIGINFAKTNKQVCTDIDECRNGACVLNSICVNTLGSYRCGPCKPGYIGDQMRGCKM ERNCRDPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYV PNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNSDKDIFGDACDNCRNVLNNDQKDTDGD GKGDACDDDMDGDGIKNILDNCQKVPNRDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQD SDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDRNSDGVG DICEADFDQDQIIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLA VGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGV TIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDK >XP_040196487.1 thrombospondin-4 [Rana temporaria] MPKRKNLLLTLLVLLELYWECEAQANYQVLDLLSPAVQRQVTNYLQQALNNPSMNEVYVLSTFKLQPKST VTLFGLYSTKENSRYFEFTVMGRLNKASLRYLKSDGRLNSVIFNNIELADGKQHSLLLHLSGLHRGPSAA ELYLDCIQVDAIKDLPRPLTGLNLNTGSVQLKTLQKKGQDSMDELKLVMGGSLTQVASIQECFMQQSEPG QYAGDVSRQLLGQISQLNQLLGELRDVMRQQVKETMFLRNTVSECQACGLTPDYPLPTQPPKPKPTTPPK PRCAATSCFQGVRCIDTESGFQCGPCPEGYTGNGIICTDTDECRLNPCFPGVRCINTIPGFRCESCPPGY TGPIVQGVGTTYARQNKQICLDINECENGRNGGCVTNSICTNTMGSFRCGPCKSGFVGDQIKGCKAEKSC SIRGSNPCHAGAQCIEEKGGEVTCICSVGWAGNGYFCARDTDIDGYPDEALLCSDPSCKKDNCIYVPNSG QEDTDKDGIGNSCDDDADGDGIMNEQDNCVLVANINQKNSDQDIFGDACDNCRFKLNNDQRDTDNDGEGD ACDDDMDGDGIKNFLDNCQRVPNVDQKDKDGDGVGDACDSCPDIVNPNQSDIDNDLVGDSCDTNQDSDGD GHQDSTDNCPTVINSSQLDTDKDGLGDECDDDDDNDGIPDLIPPGPDNCRLVPNPGQEDDNNDGVGDICE SDFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWIVLNQGMEIVQTMNSDPGLAVGYT AFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAIKSKTG PGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWFLQHRPQDGYIRARFFEGSELVADSGVTVDT TMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQAFQAQQFTS >XP_043326699.1 thrombospondin-4 [Cervus canadensis] MLAPRGATVLLLHLALQPWLGAGAQATPQVFDLLPSASQRLNPSVLQPILTDPTLNELYVISTFKLQSKSSATIFGLYSS ADHSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLQLADGRRHRLLLRLTNLHRGAGSVELFLDCTRVDSIHNLPRAF SGLAQSPEAVELRTFQRKAHDSLEELKLVVRGSLIQVASLQDCFLQQSEPLATTNTGDFNRQFLGQMSQLNQLLGEVKDL LRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVPVVPAASPTPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGN GIACSDVDECKYHPCYPGVRCVNLAPGFRCDACPVGFTGPMMQGVGINFAKTNKQVCTDIDECRNGACVLNSICINTLGS YRCGPCKPGYIGDQMRGCKMERNCRDPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSAR NCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNSDKDIFGDACDNCRNVLNNDQKDTDGD GKGDACDDDMDGDGIKNILDNCQKVPNRDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDST DNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDRNSDGVGDICEADFDQDQVIDRIDVCP ENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIF GYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVS YRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLD K >KAB0343956.1 hypothetical protein FD754_020882 [Muntiacus muntjak] MLAPRGATVLLLHLALQPWLGAGAQATPQVFDLLPSASQRLNPSVLQPILTDPTLNELYVISTFKLQSKSSATIFGLYSS ADHSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLQLADGRRHRLLLRLTNLHRGAGSVELFLDCTRVDSIHNLPRAF SGLAQSPEAVELRTFQRKAHDSLEELKLVVRGSLIQVASLQDCFLQQSEPLATTNTGDFNRQFLGQMSQLNQLLGEVKDL LRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVPVAPAASPTPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGN GIACSDVDECKYHPCYPGVRCVNLAPGFRCDACPVGFTGPMMQGVGINFAKTNKQVCTDIDECRNGACVLNSICINTLGS YRCGPCKPGYIGDQMRGCKMERNCRDPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSAR NCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNSDKDIFGDACDNCRNVVNNDQKDTDGD GKGDACDDDMDGDGIKNILDNCQKVPNHDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDST DNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDRNSDGVGDICEADFDQDQVIDRIDVCP ENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIF GYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVS YRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLD K >KAB0375369.1 hypothetical protein FD755_013861 [Muntiacus reevesi] MLAPRGATVLLLHLALQPWLGAGAQATPQVFDLLPSASQRLNPSVLQPILTDPTLNELYVISTFKLQSKSSATIFGLYSS ADHSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLQLADGRRHRLLLRLTNLHRGAGSVELFLDCTRVDSIHNLPRAF SGLAQSPEAVELRTFQRKAHDSLEELKLVVRGSLIQVASLQDCFLQQSEPLATTNTGDFNRQFLGQMSQLNQLLGEVKDL LRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVPVPPAASPTPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGN GIACSDVDECKYHPCYPGVRCVNLAPGFRCDACPVGFMGPMMQGVGINFAKTNKQVCTDIDECRNGACVLNSICINTLGS YRCGPCKPGYIGDQMRGCKMERNCRDPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSAR NCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNSDKDIFGDACDNCRNVVNNDQKDTDGD GKGDACDDDMDGDGIKNILDNCQKVPNHDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDST DNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDRNSDGVGDICEADFDQDQVIDRIDVCP ENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIF GYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVS YRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLD K >NP_001087096.1 thrombospondin 4 S homeolog precursor [Xenopus laevis] MPRGKGLCLFLQMLLLHLYGVCQAQPNYQVFDLLSVSVQRQVTSFLQNALSNPSMNEVYVLSTFKLQPKSTVTLFGLYST SDNSRLFEFTVIGRLNKASLRYLRSDGKLHIVFFNNIDLADGKQHTLLLHMSGLHRGSSFADLYLDCHPVAGVKDLPRPL SGISHNTGSVLLRTLQKRGQDSMDELKLVMGGTLSQIGSIQECFMQQSEPGQQTGDVSRQLIGQITLMTQLLGELRDVMR QQVKETMFLRNTISECQACGLGPDDPLPTEAPKRQTTTAPPKPQCDASSCFRGVRCINAETGFQCGPCPEGYTGNGVICT DVDECQLNPCFPGVRCINTSPGFKCESCPPGYTGSTIQGIGINFAKQNKQVCTDINECENGRNGGCTSNSLCINTMGSFR CGACKPGYVGDQIKGCKPEKSCRHGQNPCHASAQCSEEKDRDITCTCSVGWAGNGYLCGKDTDIDGYPDEALPCPDKNCK KDNCKYVPNSGQEDTDKDKIGDACDEDADGDGILNEQDNCVLAVNIDQKNSDQDIFGDACDNCRLTLNNDQRDTDNDGKG DACDDDMDGDGIKNILDNCQRVPNVDQKDKDGDGVGDACDSCPDIINPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNC PTVINSSQLDTDKDGIGDECDDDDDNDGIPDTVPPGPDNCRLVPNPGQEDDNNDGVGDVCEADFDQDTVIDRIDVCPENA EITLTDFRAYQTVVLDPEGDAQIDPNWIVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTLTDDDYAGFIFGYQ DSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKSGPGEHLRNALWHTGDTNDQVRLLWKDPRNVGWKDKVSYRW FLQHRPQVGYIRARFYEGTELVADSGVTVDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQAFQAQQFSS >XP_030290980.1 thrombospondin-4-B-like [Sparus aurata] MGVWTALILASQLLLKLCLHVEAQALVYDLLTSPDCLPDLLQGGLAGQGVNEAFILATFKLQPKTGTSVFGLYNPRDNSK YFEFTVMGKLNRAVLRYLRSDNRMSSVTFNNLVLADGQQHRLLFHLRGMQQQGPGGVELHLDCRLVETVRDLPAAFQGLP AGYGMVELKTMQARDQESLDELKLVVGDSFENVASLQDCHFQQRDSVQTLGVNTKQLSNQMLELTKVINELKDVLIQQVK ETSFLRNTISECQACGLGGSEPVKPKCVSGVCFRDDMCQETAEGVECGPCPDGYTGDGFNCDDVDECQFNPCFPGVKCVN TAPGYRCDACPLGYSGLAVEGVGVLFAQTNKQVCDDVDECKGPNNGGCTENSQCHNSVGSYHCGSCKSGFTGDQVKGCKP ELSCGNSLTNPCDINAQCIPERDGTITCQCGIGWAGNGYLCGKDTDIDGYPDEKLKCKDPNCKKDNCVYVPNSGQEDADR DGYGDTCDDDADGDGIPNEQDNCWLKPNVDQRNSDKDSHGDACDNCRAVENPDQRDTDGDGKGDACDDDMDGDGLKNFLD NCQRVQNRDQLDRDGDGVGDACDSCPDIPNPNQSDIDNDLVGDSCDTNQDSDGDGHQDTKDNCPLVINSSQLDTDKDGLG DECDDDDDNDGIPDTLPPGPDNCRLVPNPDQIDDNNDGVGDVCESDFDQDKVIDRIDNCPENAEVTLTDFRAYQTVVLDP EGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTY WQATPFRAVAEPGIQLKAVKSQSGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYLQHRPQVGYIRARFYE GTELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFSTQHGVDSL >XP_015798465.1 PREDICTED: thrombospondin-4-B isoform X1 [Nothobranchius furzeri] MLVWTTLILASQLLNVEAQALVYDLLTSPDCLPDLLQGGLAEQGVNDAFILTSFKLLPKTGTTVFSLYNPRDNSKYFEFT VMGKLNRAVLRYLRSDKRMSSITFNNLVLADGQQHRLLFHLKGLQQQEPGGVELHLDCRLVETVRDLPAAFRGLPAGYGL VELKTMQARAQESLDELKLVVGDSFENVASLQDCHFQQRDSVQTLGVNTKQLSNQMQELTKVINELKDVLIQQVKETSFL RNTISECQACGQNIHSLGGTEVVKPSCGPGVCFRDDMCIETADGVECAPCPDGYTGDGFNCDDVDECQFNPCFPGVKCVN TAPGFRCDACPLGYIGLPVEGVGIVFAQTNKQVCDDVDECKGPDNGGCTQNSHCHNSVGSFYCGSCKTGFTGDQVKGCEP ELSCGNSLTNPCDVNAQCVRERDGSISCQCGIGWAGNGYMCGKDTDIDGYPDEKLKCKDPNCKKDNCIYVPNSGQEDVDR DGLGDTCDDDADGDGIPNEQDNCWLKPNVDQRNSDKDSHGDACDNCRLVENPDQRDTDEDGKGDACDDDMDGDGLANFLD NCQRVQNRDQLDRDGDGVGDACDSCPDIPNPNQSDVDNDLVGDSCDTNQDSDGDGHQDTKDNCPFVINSSQLDSDKDGLG DECDDDDDNDGIPDLLPPGPDNCRLVPNPEQVDDNNDGVGDICESDFDQDKVIDRIDNCPENAEITLTDFRAYQTVVLDP EGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTY WQATPFRAVAEPGIQLKAVKSKSGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYLQHRPQVGYIRVRFYE GSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFSAQHAVDSI >XP_004074610.1 thrombospondin-4-B [Oryzias latipes] MDMWRTLLLTSQLLLNLCLHVEAQALVYDLLTSPDCLPDLLQGGLIEQGVNEAFILTSFKLQPKSGTTVFSLYNPRDNSK YFEFTVMGKLNRAVLRYLRSDRRMSSVTINNLVLADGQKHRLLFHLRGLQQQGPGGLELHLDCRLVETVRDLPAAFQGLP TGYGTVQLKTMQPREQESLDELKLAVGDSFESVASLQDCHFQQRDSVQTLGVNTKQLSNQMMELTKVINELKDVLIQQVK ETSFLRNTISECQACDLGGSEVVKPKCSPGVCFRDDMCIETANGVECAACPDGYTGDGFNCDDVDECQFNPCYPGVKCVN TAPGFRCDACPLGYIGLPVEGVGIVFAQTNKQVCDDIDECKGPSNGGCPANSNCENSMGSYHCSCKTGFIGDPVKGCKPE VSCGNSLTNPCHANASCVLERDGSISCQCGIGWAGNGYLCGKDTDIDGYPDEKLKCKDAHCRKDNCIYVPNSGQEDADRD GQGDACDEDADGDSIPNELDNCWLKPNVDQKNSDSDSHGDACDNCRLAKNPDQRDTDGDGKGDACDDDMDGDGLKNFLDN CQRVQNRDQLDRDGDGVGDACDSCPDIPNPNQSDIDSDLVGDSCDTNQDSDGDGHQDTKDNCPYVINSSQVDSDKDGLGD ECDDDDDNDGIPDVLPPGPDNCRLVPNPDQMDDNDDGVGDVCESDFDQDKVIDRIDICPENAEVTLTDFRAYQTVVLDPE GDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYW QATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNHQVRLLWKDPRNVGWKDKVSYRWYLQHRPQVGYIRARFYEG TELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFRAQHAVDPI >XP_043732019.1 thrombospondin-3 [Cervus elaphus] METQELRGALALLLLCTFASASQDLQVIDLLTVGESRQMIAVVEKIRTALLTTGDIYLLSTFRLPPKQGGVLFGLYSRQD NTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTALLRLRGPSKPSPALQLYVDCKLGDQHAGLPALAPI PPAEVSGLEIRTGQKAYLRMQGFVESMKMILGGSMARVGALSECPFQGDESIHSAVTNALHSILGEQTKALVTQLTLFNQ ILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCTDINEC AHADPCFPGSSCINTMPGFHCEACPRGYKGTRVSGVGIDYARASKQVCNDVDECNDGNNGGCDPNSVCTNTVGSFKCGPC RLGFVGNQSQGCSPARTCHSPAHSPCHVHAHCLFERNGAVSCSCNVGWAGNGNVCGPDTDIDGYPDQALPCMDNNKHCKQ DNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGD ACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCP QLPNSSQLDSDNDGLGDECDGDDDNDGVPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAE VTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQD SGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGNTPDQVRLLWTDPRNVGWRDKTSYRWQ LLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVPEDFEPFRRQLLQGRV >XP_039274396.1 cartilage oligomeric matrix protein-like [Styela clava] MDFYSVLVFIASFIVGIESIKKSSMFMSEVDLLRAARSEKSAIRVTEKVARTLTKAHTISLAFELKVPPEEFVSVFAIYE KTGPRKYFEITVNGRQDKVSIKSRDESDADDDELHVTSFRKVGIANGQWHTMLIHFVITDSGVAETHFILDCAEKGRAEH PWIADQIRKSRNSTLIVKLGTKSTIDIKTHMRKAVLLHDEQLPIVRRNYGGYCTQADMGIGSDPTLLNMMNNFEPVSELI IQISDLASVLRDIHAGMKAQAIETKELRRTLQQCSACTGEKSLYSQPTQSVSPTQGRFQVTEPPQPSIIKVEEPTEPPVI RKCSSNPCDSQVECEDTEDGFTCGRCPSGFTGNGIHCDDIDECETSFDPCSAIAGCINTQGGYYCNLCPEGGFEQSYKEI EVAERIIQKQVCTDIDECKVDNGGCAEFSKCINTAGSYKCGACIPGYHGNQTSGCVKVRQCSDGALNPCDVNAECLVINT AEEYACECNAGYSGNGYVCGLDGDLDGYPNEQMPCNVKNCRQDNCPEVPNSGQEDSDLDGLGDACDSDADDDGISNDEDN CVLVPNKDQQNSDSDLFGDACDNCPNANNPQQLDHDDNGKGDECDTDIDGDGIGETLENCPFVPNVSQDDMDGDSVGDAC DNCPTMSNPMQSDSDHDSIGDVCDTNTDSDGDGRQDNMDNCPHVLNCAQLDTDNDGKGDACDEDDDNDGIPDYGKQTDNC RLINNPNQLDDDGDNIGDACENDQDGDGVVDWKDVCPYNRDISVTDFRSYQKVMLDPDESEVEPSWIVANEGMEITQKTN SDPGLLVGLDSFDGVDFSGTFFVNTASDDDYAGFLFSYQSSRKFYVVMWKQTSQEFWDDEPFRALALSGLHIKAVDSATG PGPDLRNALWHSGDTPNQVRTIWSDPNNVGWKDKTAYRWELKHRPETGYIRLKFYEVNKLVADTGAIIDNTVKGGRLGVF CFSQERIIWSHLKYKCNEAYPEDY >XP_030832707.1 cartilage oligomeric matrix protein isoform X1 [Strongylocentrotus purpuratus] MQFGTCSIAFLLMLSVTSSQIPVSMGVEADLFDGFGIYNSRIPGVSPAPQENSNIYGDAFFFNGISIRYPIIANQEFFKK FAKEMRKNEDVYFVIRSRLAPRHHGVLFGVYSSNYYSQDTFRTPLRFELSYNGTNGGKLVLKYRVGDQQRQAEFPNLLVV DGDWHTIILQFHTERSSTTLTLYVDCRLANQMKIGDKLSRVFSRTVIDGSEMRLGQAGYGMTANPLKGTIQNVRFMYGGP IGDVLHSLSCSLSTEPKPLDADGWPGATILMDAFQSLSSTLMVLKNGMDDQTREIRHLRNTLENCRMCERTDYFTSGPQT IITHGCSSNPCFPDVMCFDEPDGLGYRCGPCPAGYRGNGSYCYDINECIEAYPCSDVVECINLVPGFRCPPCPEGFIGLG LEGIGLEAAVRNRQVCDDINECERNNGDCVPNSYCINTRGSHICGDCKHGFEGNQTVGCKQKNTCPNGERSPCHPKAKCI IHRNNAYTCECIIGWAGDGYDCALDTDLDGYPDYALPCTDKHCRADNCVYIPNSGQENQDGDEMGDICDPDADNDGVPNG PDNCPLVANPDQVNSQDDDPVGERCDNCPMTPNPKQIDTDADGKGDECDDDKDNDGILNIYDNCELVPNRMQDDTDGDGL GDACDNCPMQYNPDQNNTDSDLLGDICDNNEDSDDDGIQDNLDNCPKIPNNPQLDSDGDGRGDACDDDDDSDGVYDIVDN CRIIHNPDQADYNQDGIGDMCDSDFDRDGVDDQYDACPENPNIFTTDLRTYQTVVLDPEGEAQVDPKWIVFDEGRQIMQT INSDPGLAISYQAFDGVDFEGTFFVNTRTDDDFAGFVFGYQDSASFYVLMWKQGPQTYWEASPFRAVGEPGFQLKVIKSD TGPGEMMRNALWHTGDTPGQSRLLWKDPNNHGWKDHVAYRWRVVHRPSIGLIRVKLYEADSLVADSGFLRDTTMRGGRIG LFCFSQEDIIWARITYKCNDDIPEGVTF >CAE1249094.1 THBS2S [Sepia pharaonis] MIALIAPADAQFRPLRKPEIGAAFMRYNELSLVGEIQLQSNRRRGRATLLRAENLAMNTKFDSYIDFQRAEVVINLKTKD GREYAVRFLTGVLSENKNKKIIIRFTNLQSNSNGIQLFVNCMNAGRDNTELPIRDVLMGNFSVQRHPAFKLYGQASLKEL LMMQGCEDTENIAPTRPSIPKPSLPSWVGSIDPDRRFPDIDIKRETHSREVSQDPFYTVDQIKTDRIHHSTIDSVKPELP NAIVELTIAIRDLQRDFQNQIRETHLLKETLKECQMCRGTPPEPGNLRRCSSNPCFQGVRCIDTEEGFRCGSCPPGFYGD GKTCSAYLTCNDRPCYPGVQCSDTSSGFICGPCPTTLTGDGTVHGCHPTRVTCDSSPCFPGVMCTDQRTGFHCGSCPTGY TGNGTYCEDLDECQFSRPCDRRATCTNLSPGFTCTPCPQGYTSSPITGIGILSAQQTRQICQDIDECRSNNGGCVPHSRC INTRGSFRCSECDPGYSGNQTVGCRRQISNCSNGKECHKNARCIQRPESSTHECQCSIGYGGDGYYCSKDQDLDGIPDNA LPCGHRKCRKDNCVSTPNSGQEDADGDGLGDACDPDADNDGIVNNPDNCPLVANPDQDDTEDKPDRKGDACDNCPTIPNP EQTDTDDDGMGDTCDPDADNDGIINAHDNCIRVKNADQRDTDGDGIGDACDNCPFVPNVKQLDSDADLTGDACDTNDDKD DDGVQDTNDNCPHIANSDQLDTDGDTLGDICDNDDDNDGVLDVNDNCPLRMNPRQEDEDGNGVGDICEIDKDGDGSEDFI DVCPHNGNIYATDFRAYQTVILDPEGDSQIDPNWVILNQGAEIVQTMNSDPGIAISYTAFAGVDFSGTFYVNTEVDDDYA GFIFSYQDSSHFYVVMWKKNTQTYWHSTPFRAVAEPGIQLKLVNSSTGPGQYLRNALWHTGDTHDQVRLLWKDPRNEGWK ERKAYRWELIHRPYKGLIRILFFEETELIADSGNIYDFTLKGGRLGVFCFSQEMVIWSDLVYRCNDYIPPGLLEEEDYGY GQ >XP_031556620.1 cartilage oligomeric matrix protein-like [Actinia tenebrosa] MKKSGSIWYLQSLLVLLSMVLNTEAKIQDFDLIKSFELGKGQITGLGRIEGYPGEPEEAYRFDRGLARLHLGPEFVSDLA EASRESKSLTITSNLKLDRKSYGTLLSIETEGEGNLVFSLLFSCFSSCRISLYYPEGSLTSVTYFDKVPNISDGKWHKMV LHIQTNRMGKHVVSLFMDCRSLGKKKISAGLDQLFPLSNEKVKYALRFAQRGASNSVYIPWKGSLQSVLLIFGVRSHSFA NPVDCLTKSTRQILSGLTNKNNRHKYQPTVKVVTTQRRQTTSKDATTVKSTPTKPQKDGTTKPQPSVRPITQKEKPTRNI VDIITSGETRFGVADGSSPTTELVLTTSDEKLDYLVDMIRQLKKEQFHRESALRKTIEMLRIDLNSQSQEVRYVRSFLEH GGACKSGSLIQQTGKRFDSIGTILPGRKTDRQNPVAGGKCLQKPCFPFVECYETPDEGLGFRCGPCPPGFTGNGIRCEDV NECNLYPCSALTKCINLRPGYQCTPCPVGYLGNASMGLGVEMARKNKQVCEDINECANGRNGGCSIHSECINTQGSYRCG PCKPGYDGDSTRECKRVLFCSNAPRANPCGKLAHCIPRNDGRNYECKCKPGYGGDGVRCGKDSDMDGYPDRALGCKGPKC AKDNCREIPNSGQEDVDGDGTGDACEYDADGDRKPSKDQDNCPSVPNEDQQDTDADGVGDACDNCQTVNNPDQEDTDKDG IGDACDVDIDGDGIINVLDNCPKVPNRDQKNTDGDPHGDACDNCKRGKNPDQADKDGDGIGDVCDFDQDYDRDGVDDRHD NCLRKPNAAQLDTDGDGLGDVCDSDDDNDGIPDYKDNCRLVRNVDQKDSDNDGIGDACQGDYDNDGVPDAVDICPYNHNI TKTDFSSFFNVNFDPLSKIKDYPQWKASKKGNEVYLRKNSNVGLFVATPKYEDIEFRGTMFVNTHQDDDIIGFAFGYQQY GHFFLLSWKRKEQMYWIVNPFRATAKTWLTLKRVKSSSVPSHGIRNALWHTAETRRHTKVLWQKRLTRGWKPKTAYRWEL NYTPSNGYLRLQMWVGTQQLMDTGILRDLEMRGGRLGFFSFSQGDIIWSDLQVRCVDGK >XP_397221.5 cartilage oligomeric matrix protein isoform X1 [Apis mellifera] MRVIITLIITIFFLVYVVDSSITRDEDLEKNLRERWNDDFVIVFSNIKSKKKQFQVMVEVLLTIKYEKSKMVLMLDRRAK RVILENIDEVGHRVAQYINMDNLNVNSNFPSKNVIFLVHQSQPGARMAVYIDCIYRGVIPLKKTFRELTNSEDNLLIEAF RERKSQVKVYPLARSMEALQEENCLSTLTDTNTESQELRSIDDNNNFETPSFNSARVNLRNKQNHHVHRSKEHNHDETVD LFEDTDQIDLNSRQSNHNRHSVRDRSNRYKHENDRNKYLEFDQDFSSLMKRLQQPEYFNEPIQEKFEVLSNLNESDILNQ PINIYHKRVPRRGDIGIQSLDERVCLTDNQIVKTLNELIGATKKIWREIELNRLETHRVLLLIENCAACREPPPVPLTTT TPAPPSCSYKSPCFPGSECRDTPRGPQCGACPPDYTGDGYRCVKITCAHNPCFKGVRCYDQSDRYSCGNCPIGYIGNGKH CELKNVCEPNPCYSEVQCDLISEPPFYRCGVCPNGFTGNGSVCVDINECEIAQPCSLGVQCINLHPGFRCDPCPPGYTGT MIEGVGLEIAMNRKQICQDINECENNNGGCDPYMECINMQGSYRCGACRAGFIGNQTVGCHPAHSICPDLITRCDVNAEC VCIDTNVYSCRCRVGWTGDGLICGIDRDNDGIPDRNLHCRDRHCRMDNCPLTPNSGQEDADRDGIGDACDPDADDDGVLN SSDNCPFISNPGQEDNDSDGPDLVGDICDNCPRVRNPKQEDTDDDGIGDACDPDIDNDGIPNNQDNCQKIKNQNQNDMDE DGIGDACDNCPYGYNPNQLDQDGDGVGDDCDNDNDRDRDGVQDDRDNCPDVANSGQNDDDHDGIGNECDNDMDNDGVPNS NDNCPYVYNPDQRHTHNNFIGDACWHDYDNDTVKNIHDNCPNNSLIWATDFRKYTTIALDPFGTAQEDPVWVIHNDGAEI QQLVNSDPGIAIGPDIFSGVDFEGTFFVDDDGDDDFVGFVFSYQDNRRFYIVAWKKAHQPYWVPTPFRAVGDPGIYLKLV DSDTGPGEILRNSLWHNENTINQVKILWHDPKKIGWKERTSYRWQLLHRPKIGLIRFRLYQGKQLMADSGNVYDSTLKGG KLGVYCFSQEKITWSNLLYVCKETVPLSVWNDLPSNLRKEINVDINNEIKSQYSQKSIYYDSH >NP_001137802.1 thrombospondin, isoform F [Drosophila melanogaster] MNWTRVLLIGLTALALTFVDVASLSLDPVASAELEQFIRKGDVVISTRHIRPRRKLHISIEALFMIDFPMLKHKMSFFLD RKQQRVTLDISANGATESRNFEIPNINETSTIRSLALQFSKNRITLHVDCKASTHHDIDMNLAKLYTQMDDPVIKLFRER KYPLHFDGDMEHSLQRANCQKGNHRRGNRRMLRNKITEREKNKKRDVRGWYEPTIAREGVVDHRHQEVPTDVERGDIPVL NGDCEDALARSLSDLLALVKLLREDVAHQRQEIAYLRMLLENCAGCKNPLTTDNQLRIEPDCRSANPCYPGVECLDSAAG PRCGHCPLGFIGDGKSCKPGVTCAHHMCYPGVQCHDTVNGAQCDSCPAGYEGDGRTCSLRNPCLDTPCPSGAQCLQVGYP PYFHCISCPMGHEVNGTSCRDMNECLLYDPCDELATCTNLSPGFQCSPCPVGFDGTHAHGYFADYYSVDYRRQTCLDVDE CRTGFFRCPEHSTCINEIGSYRCQCHEGYVTNGTYSCLDRSSVFMCPDGTVCDRNAVCLRMDNIRHKCHCNVGWAGNGLI CGRDTDVDGWPDQAIGCPELRCQRDNCPKLPNSGQEDADLDGHGDGCDDDADGDNVQNSQDNCWLAYNTEQLDSDGDKVG DVCDNCVLKYNPRQLDTDEDGLGDECDGDIDNDSIPNALDNCPLLPNPSQSDVDNDGVGDACDNCPNLPNPDQKDRDMDF VGDACHRDIDGDDDGVPNSLDNCPMVSNSDQLDTDGDGTGDECDDDMDGDGIPNYKDNCPLAKNPKQDDFNRNGKGDSCE DDEDVDGVPNGMDNCPNNSMIHHTDFRTLQTIPLDPKGLSQADPNWVVHANGTEIVQTLNSDPGLAVGKDAFGGVDFDGT FYINDDTDDDYAGFVFSYQSSYKYYVVQWKKGTQTYWEPRPFTASAAPGIQIKLVNSTEGPGPMMRNSLWHEGNTDGEAR LLWKDPKNIAWKERTSYRWSLVHRPAIGLIRLQMHEGNRLIFDSGNVFDSTLKGGRLGVFCFSQRMIIWSNLQYKCNNRV KPLIYNDLSDYLKTKVELQD >XP_038078580.1 thrombospondin-1-like isoform X1 [Patiria miniata] MPTRATMARLTYYVFAFGFLCSALHCQLTKAYEEVDVMLASGISARTPGVRETKTPEGGRAFKVRPKDRDLGTDQGSLER LLRSMKADEGFILITVAYQDPKNRGTLVSVDRTDGQVRGFGFHIDRRNDEAVVQFAEFGAGEPQESQVVFSPLNIGKDDT ELHTFVLDVRGNLVTLYMDCQLIGLKILPSSFYMNMEPDNMKLRLGKGLPDRNNVLDFKGTLAVAKFAFQTSTTDVLISQ GCEIEPVFSSSQISFGSSFPLPIGESEPSHISSDAAMPGGEGNVEQSTPNNNNHGDSGSFGNSGLSDSMSFGGAIPVPPG GSFSNLNPGVPSSTGGTSGNVMPQPVPGTPPHLPTNMGYMHPNAAPTDDTMQGQCAYTCEQISNLNNQVQVLSDGYDDMW NKLEHFENQRPPEWPSQQGCWYMKTLYDDGDVFKVDKCKSCECRVEGGLPTVECSLIKCQPGKCANPIIMEGDCCPTCPN DNLGWSDWAEWTSCSVTCGNGIQQRGRSCDRTQFECNGNDVETRVCYLDPCIEIVDGGWSNFTPWSCGVTCGNGTESRMR SCNSPRPKNGGKRCDGELDGAGREERPCGRDPCPVDGQWGQFSEFTPCTKTCDGGWQERYRFCDSPPPAHGGRDCVGSDT HRRMCNEWPCPIDACLSSPCFDGVECVSFTDGRYECKDCPVGYTGNGILCQDINECLLVSDACFNFHGEHRCLNLIPGYT CRKCPIGYRGNQPSGMGVYHAKRYKQQCIPINPCAEGTSSCHIDARCIFYGPYSDPQYGCKCKTGFAGDGVHCGYDSDLD GWPDEQLDCEDHGDYTHCTRDNCASLPNSGQEDNDGDGKGDACDADDDDDLVDDVADNCQFISNWQQFDIDDDGVGDVCD NCPFVSNTRQEDTDSDGDGDVCDYDIDEDGIYNEDDNCMYVANARQLDFDEDGYGDVCDNCPDYGNPDQMDIDDDNVGDV CDTDRDVDNDGHQDDLDNCWNIANSDQADHDMDGIGDACDFDDDNDGIEDVDDNCRLIFNPSQNDTNENGRGDACEYDND GDGVTDLQDACPDNANIQRTDLSHFQLIKLDPEGSAQIDPHWIVRNRGQELVQTINSDPGLAIGYDEFNSVEFSGTFYVN TERDDDYAGFVFGYQSNHRFYSVMWKQVTQKYWEPMPTMSEATAGLQLKLINSTTGPGEYLRNALWHTGDTSDQVKLIWS DANKIGWKDFTAYRWILTHRPRTGYIRVTMYEGSKVLADSGALYDFTLQGGRIGLFCFSQEMVFFSDLQYKCLAEE
Mafft alignment of selected proteins >sp|P35443|TSP4_HUMAN Thrombospondin-4 OS=Homo sapiens OX=9606 GN=THBS4 PE=1 SV=2 ----------------------------------------MLAPR-------GA---AVL ---------LL-HLVLQRW----------------LAA-----------------GAQAT PQ----------VFDLLP-------------------------------SSSQRLNPGAL LPVLTD-PALNDLYVISTFKLQT---KSSATIFGLYSSTDNSK-------YFEFTVMG-R LNKAILRYLK----NDGKVHLVVFNNL-QLA--DGRRHRILLRLSNLQRG-AG------- -----SLELYLDCIQVDSVH------NLPRAFAGPSQ----KPETIELRTFQR------- -KPQDFLEELKLVVRGSLFQ-----------------------------VASL------- ---------------QDCFLQQSEPLAATGT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMTQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLKFQSPTP-STVVPPAPP-------------------- ---------------------------------------------AP------------- ------------------------------------------------------------ ------PT---------------------RPPRRCDSNPCFRGVQCTDSRD---GFQCGP CPEGYTGNGITCIDVDECK-Y-HPCYP---GVHCINLSPGFRCDACPVGFTGPMVQGVGI SF--AKSNKQVCTDIDECR---NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAER N---CRNPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLIHNV DQRNS-DK---DIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKF PNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICES DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRFDN------------------------------------------ >tr|F1R1P9|F1R1P9_DANRE Thrombospondin-4-B OS=Danio rerio OX=7955 GN=thbs4b PE=3 SV=1 ----------------------------------------MAGTM-----------HLLT ---------AV-SLILMLS------------------------------------SANAE SI----------VYNLLT---------------------------------SPDCLPDLL HGGLAE-QGVTELYILTTFRIQP---GTGNTIFSLYNPRDNSK-------YFEFSVFG-K ANKAILRYLR----RDGRMSAVTFNKL-NLA--DGEKHRLLFHLKGLEVGHPGGFPHSQG ALPVPGVELHLDCRLVETLR------DLPAVFNGLN-----NHQAVELKTMQG------- -KAQEGLEELKLAYGDSVEN-----------------------------VASL------- ---------------QDCH-TQSDS--VQAL----------------------------- ------------------------------------------------------------ ----------GL-----------------------------NTKQLTTQMLELTKVINEL KDVLIQQVKETSFLRN-------------------------TISECQAC------G---- -------------------LSGAE------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------VVKPKCAPGVCFRDDMCIETAE---GVECGP CPDGYTGDGYSCDDVDECQ-F-NPCFP---GVRCVNMAPGFRCEACPLGFTGKPLEGVGV AY--AQTHKQVCDDIDECKGPDNGGCTANSICVNSVGSYQCGRCKTGFTGDQIRGCKPEK S---CGNRL-QNPCDPNAQCTE---ERDG-TITCQCGIGWAGNGYLCGKDTDIDGYPDER LRCRD----PTCRKDNCVTVPNSGQEDADGDGKGDACDPDADGD-GILNEQDNCWLTPNI NQQNS-DK---DSHGDACDNCVRVDNPDQRDTDSDGLGDACDDDMDGDGLKNFLDNCQRV KNRDQLDRDGDGVGDACDSCPDIPNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSKDNCPM VINSSQLDTDKDGIGDECDDDDDNDGIPDSLPPGPDNCRLVPNPEQIDDNNDGVGDICES DFDQDKVIDRIDNCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYL QHRPQVGYIRVRFYEGTELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFSTQHGMDPL------------------------------------------- >NP_035712.1 thrombospondin-4 precursor [Mus musculus] ----------------------------------------MPAPR-----AAAA---AFL ---------LL-HLVLQPW----------------QRT-----------------SAQAT PQ----------VFDLLP-------------------------------SSSQRLNPSAL QPVLTD-PTLHEVYLISTFKLQS---KSSATIFGLYSSSDNSK-------YFEFTVMG-R LNKAILRYLK----NDGKIHLVVFNNL-QLA--DGRRHRVLLRLSNLQRG-DG------- -----SVELYLDCAQADSVR------NLPRAFSGLTQ----NPESIELRTFQR------- -KPQDFLEELKLVVRGSLFQ-----------------------------VASL------- ---------------QDCFLQQSEPLAATST----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMTQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLVPIAPP-------------------- ---------------------------------------------AP------------- ------------------------------------------------------------ ------PT---------------------RPTRHCDSSPCFRGVRCTDTRD---GFQCGP CPDGYTGNGITCSDVDECK-Y-HPCYP---GVRCVNLAPGFRCDACPVGFTGPMVQGVGI NF--AKTNKQVCTDVDECQ---NGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCKTER S---CRNPE-QNPCSVHAQCIE---ERQG-DVTCVCGVGWAGDGYVCGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLTHNI DQRNS-DK---DIFGDACDNCRMVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPRV PNRDQQDRDGDDVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSSQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNNDGVGDICEA DFDQDQVIDHIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQSFDRLDN------------------------------------------ >NP_058829.1 thrombospondin-4 precursor [Rattus norvegicus] ----------------------------------------MLAPR-------AA---AFL ---------LL-HLVLQPW----------------QRA-----------------GAQAT PQ----------VFDLLP-------------------------------SSSQRLNPAAL QPVLTD-PTLHELYVISTFKLQS---KSSATIFGLYSSSDNSK-------YFEFTVMG-R LNKAILRYLK----DDGKIHLVVFNNL-QLA--DGRRHRILLRLSNLQRG-AG------- -----SVELYLDCVQVDSVN------NLPRAFSGLTQ----NPQAIELRTFQR------- -KPQDFLEELKLVVRGSLFQ-----------------------------VASL------- ---------------QDCFLQQSEPLAATGT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMTQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLVPIAPP-------------------- ---------------------------------------------AP------------- ------------------------------------------------------------ ------PT---------------------RPTRRCDSSPCFRGVRCTDTRD---GFQCGP CPDGYTGNGITCSDVDECK-Y-HPCYP---GVRCTNLAPGFRCDACPVGFTGPMVQGVGI NF--AKTNKQVCTDVDECR---NGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCRTER S---CRNPE-QNPCSVHAQCIE---ERQG-DVTCVCGVGWAGDGYVCGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLTHNV DQRNT-DK---DIFGDACDNCRGVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCPRV PNRDQQDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNNDGVGDICEA DFDQDKVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQIQTFDRLDN------------------------------------------ >NP_001308478.1 thrombospondin-4 precursor [Gallus gallus] ----------------------------------------MGCER-------GA---ALL ---------LL-PLALQLC----------------PGR-----------------AAPPA PR----------VIDLLP-------------------------------YANKRVVTSFL QQALGD-PTLNEVFLLSVFKLQP---KSTTTIFDLYSPADDRQ-------YFEFTVMG-R MNKVVLRYLK----NDGRLNSVIFSNV-HLA--DGKPHAVILWLSGLQQE-LC------- -----TIELYLDCLQVGAIQ------DLPKAFSTLLE----RSAAVELRTFLK------- -KPEDTLDELKLVTGGTLAQ-----------------------------ARDL------- ---------------QDCFLQQIES-APQYT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQLMNQMVQMNQILGEV KDLLKQQVKETTFLRN-------------------------TIAECQAC------G---- -------------------LGTANF----------PTPLP-------------------- ---------------------------------------------R-------------- ------------------------------------------------------------ -----------------------------HTKPKCEASSCFRGVRCMETAE---GIQCGP CPEGLTGNGVTCSDVDECR-Y-SPCFP---GVRCVNTAPGFRCETCPPGYTGQTLQGVGL SY--AKNNKQVCLDIDECQNGGHGVCVPNSQCINTLGSYRCGQCKSGYTGDQIRGCQAER S---CRSRA-LNPCSVHARCIE---ERRG-EVTCICGIGWAGDGYICGKDIDIDGYPNEE LSCPS----ESCRKDNCKFVPNSGQEDADDDGIGDACDEDADGD-GIPNEQDNCVLTPNV NQRNS-DE---DIFGDACDNCRSVLNNDQRDTDGDGKGDACDDDMDGDGIKNLLDNCQRI PNQDQEDKDNDGVGDACDSCPTVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT IINSSQLDTDKDGLGDECDEDDDNDGIPDLLPPGPDNCRLVPNPGQEDDNGDGVGDVCES DFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDPRNVGWKDKVSYRWFL QHRPQIGYIRARFYEGSDLVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQAQQFGVGDI------------------------------------------ >XP_016808573.2 thrombospondin-4 [Pan troglodytes] ----------------------------------------MLAPR-------GA---AVL ---------LL-HLVLQRW----------------LAA-----------------GAQAT PQ----------VFDLLP-------------------------------SSSQRLNPGAL LPVLTD-PALNDLYVISTFKLQT---KSSATIFGLYSSTDNSK-------YFEFTVMG-R LNKAILRYLK----NDGKVHLVVFNNL-QLA--DGRRHRILLRLSNLQRG-AG------- -----SLELYLDCIQVDSIH------NLPRAFAGPSQ----KPETIELRTFQR------- -KPQDFLEELKLVVRGSLFQ-----------------------------VASL------- ---------------QDCFLQQSEPLAATGT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMTQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLKFQSPTP-STVVPPAPP-------------------- ---------------------------------------------AP------------- ------------------------------------------------------------ ------PT---------------------RPPRRCDSNPCFRGVQCTDSRD---GFQCGP CPEGYTGNGITCIDVDECK-Y-HPCYP---GVRCINLSPGFRCDACPVGFTGPMVQGVGI SF--AKSNKQVCTDIDECR---NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAER N---CRNPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLIHNV DQRNS-DK---DIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKF PNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICES DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRFDN------------------------------------------ >XP_038327488.1 thrombospondin-4 [Canis lupus familiaris] ----------------------------------------MPGPR-------GA---ALL ---------LL-HLVLQPW----------------LRA-----------------GAQGP PQ----------VFDLLP-------------------------------SSSQRLNPAVL KPILTD-PTLNEVYVISTFKLHT---KSSATIFGLYSSTDNSK-------YFEFTVMG-R LNKAILRYLK----NDGKIHLVVFNNL-QLA--DGRRHRVLLRLTNLQRG-AG------- -----SVELYLDCTQVDSVH------NLPRAFSGSSQ----SPDSIELRTFQR------- -KAQDFLEELKLVVRGSLFQ-----------------------------VASL------- ---------------QDCFLQQSEPLATTST----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMTQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLVPPAPP-------------------- ---------------------------------------------APATS---------- ------------------------------------------------------------ ------PT---------------------PPVRRCDSNSCFRGVRCTDTRD---GFQCGP CPEGYTGNGITCSDIDECK-Y-HPCYP---GVRCVNLAPGFRCEACPVGFTGPVVQGIGI SF--AKSNKQVCTDIDECR---NGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCRTER S---CRNPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCRYVPNSGQEDADGDGVGDACDEDADGD-GILNEQDNCVLTHNV DQRNS-DK---DIFGDACDNCRNILNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCPRV PNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNRDGVGDICET DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRLDS------------------------------------------ >NP_001029900.1 thrombospondin-4 precursor [Bos taurus] ----------------------------------------MLAPR-------GA---TFL ---------LL-HLALQPW----------------LGA-----------------GAQAT PQ----------VFDLLP-------------------------------SASQRLNPSVL QPILTD-PTLNELYVISTFKLQS---KSSATIFGLYSSADHSK-------YFEFTVMG-R LNKAILRYLK----NDGRIHLVVFNNL-QLA--DGRRHRLLLRLTNLHRG-AG------- -----SVELFLDCTRVDSIH------NLPRAFSGLAQ----SPEAVELRTFQR------- -KAHDSLEELKLVVRGSLIQ-----------------------------VASL------- ---------------QDCFLQQSEPLATTNT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMSQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLMPVVPA-------------------- ---------------------------------------------AS------------- ------------------------------------------------------------ ------PT---------------------PPVRRCDSNPCFRGVRCTDTRD---GFQCGP CPEGYTGNGIVCSDVDECR-Y-HPCYP---GVRCVNLAPGFRCDACPVGFTGPMMQGVGI SF--AKTNKQVCTDIDECR---NGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKMER N---CRDPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDDDADGD-GILNEQDNCVLTHNV DQRNS-DK---DIFGDACDNCRNVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCQKV PNSDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICEA DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRLDK------------------------------------------ >XP_008260094.1 PREDICTED: thrombospondin-4 [Oryctolagus cuniculus] ----------------------------------------MRAPR-------GA---ALL PLHLA----LL-HLALQPW----------------PGA-----------------GAQAT PQ----------VFDLLP-------------------------------PSGERLSPGVL QPLLAD-PALHDLYVLSTFKLQT---KSSAPIFGLYSTADNSR-------YFEFTVMG-R LNKAILRYMK----SDGKIHLVVFNNL-QLA--DGRRHRLLLRLSNLQRG-AG------- -----SVELYVDCTQVDSVH------NLPRAFAALSQ----SPESFELKTLQR------- -KAQDFLEELKLVVRGSLFQ-----------------------------VASL------- ---------------QDCFLQQSEPLAAAGS----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMAQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLVPPAPP-------------------- ---------------------------------------------AP------------- ------------------------------------------------------------ ------PTR--------------------PPRRRCDSNPCFRGVRCTDTRD---GFQCGP CPEGYTGSGITCSDVDECK-Y-HPCYP---GVRCVNLAPGFRCEACPVGFTGPTVQGAGI SF--ATSNKQVCTDIDECA---NGACTPHSVCTNSVGSYRCGPCKPGYTGDQTRGCKPER S---CRNPE-LNPCSPNAQCIQ---ERQG-DVTCVCGVGWAGDGYVCGRDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADGDGLGDACDEDADGD-SILNEQDNCVLTPNT DQRNS-DK---DIYGDACDNCRTVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPRV PNRDQRDKDGDGVGDACDSCPDISNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICET DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSQTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWFQPQVPLQRHHP RGLPGVPDPELRPPGELGRPGRSSARGPAPAPPLAAAQPPGLALTCPGARRRLLRAWQ >XP_024103393.1 thrombospondin-4 [Pongo abelii] MGHLRRRPGPRPRFNARPGDLQAGPTPPSPPASRGAGRANMLAPR-------GA---AVL ---------LL-HLVLQPW----------------LAA-----------------GAQAT PQ----------VFDLLP-------------------------------SSSQRLNPGAL LPVLTD-PALNDLYVISTFKLQT---KSSATIFGLYSSTDNTK-------YFEFTVMG-R LNKAILRYLK----NDGKVHLVVFNNL-QLA--DGRRHRILLRLSNLQRG-AG------- -----SLELYLDCIQVDSIH------SLPRAFAGPSQ----KPETIELRTFQR------- -KPQDFLEELKLVVRGSLFQ-----------------------------VASL------- ---------------QDCFLQQSEPLPATGT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMTQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLKFQSPTPSSTVVPPAPP-------------------- ---------------------------------------------AP------------- ------------------------------------------------------------ ------PT---------------------RPPRRCDSNPCFRGVQCTDSRD---GFQCGP CPEGYTGNGITCIDVDECK-Y-HPCYP---GVRCINLSPGFRCDACPVGFTGPMVQGVGI SF--AKSNKQVCTDIDECR---NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAER N---CRNPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLIHNV DQRNS-DK---DIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKF PNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICES DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRFDN------------------------------------------ >XP_020940149.1 LOW QUALITY PROTEIN: thrombospondin-4 [Sus scrofa] ----------------------------------------MLATR-------GA---ALL ---------LL-HLALQPW----------------LAA-----------------GAQAT PQ----------VFDLLP-------------------------------SASQRLNPSVL QPILSD-PTLNELYVISTFKLQT---KSSATIFGLYSSADNSK-------YFEFTVMG-R LNKAILRYLK----NDGKIHLVVFNNL-QLA--DGRRHRLLLRLTNLHRG-AG------- -----SVELYLDCTQVDSIH------NLPRAFAGLSQ----SPGSVELRTFQR------- -KAQDSLEELKLVVRGSLFQ-----------------------------AASL------- ---------------QDCFLQQSEPLAATNT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMSQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLVAPAPP-------------------- ---------------------------------------------AS------------- ------------------------------------------------------------ ------PT---------------------PPVRRCDSNPCFRGVRCTDTRD---GFQCGP CPEGYTGNGVTCSDVDECR-Y-HPCYP---GVRCVNLAPGFRCDACPVGFTGPTVQGVGI NF--AKTNKQVCTDIDECR---NGACVLNSICVNTLGSYRCGPCKPGYIXDQMRGCKMER N---CRNPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLTHNM DQRNS-DK---DIYGDACDNCRNVLNNDQRDTDGDGKGDACDDDMDGDGIKNILDNCPKV ANRNQQDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPGQEDSNSDGVGDICET DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRLDN------------------------------------------ >XP_019465735.1 thrombospondin-4 [Meleagris gallopavo] ----------------------------------------M------------------- ------------------------------------------------------------ -R----------VIDLLS-------------------------------YANKREVTSFL QQALGD-PTLNEVFLLSAFKLQP---KSTATVFGLYSPADDKQ-------YFEFTVMG-R MNKVVLRYLK----NDGRLNSVIFSNV-HLA--DGKPHAVILWLSGLQQE-FC------- -----TIELYLDCLQVGAIQ------DLPKAFSAQLE----RSAAVELRTFLK------- -KPEDILDELKLVTGGTLAQ-----------------------------ARNL------- ---------------QDCFLQQIES-APQYT----------------------------- ------------------------------------------------------------ ----------GK-----------------------------ASNQFI-QILVQKSCGGEY SSFCIK-------------------------------------------------G---- -------------------LGMVNF----------PTPLP-------------------- ---------------------------------------------R-------------- ------------------------------------------------------------ -----------------------------RSKPKCETSSCFRGVRCMETAE---GIQCGP CPDGFTGNGVTCSDIDECH-Y-SPCFP---GVRCVNTAPGFRCETCPPGYTGQTLQGVGL SY--AKNNKQVCLDIDECQNGGHGVCVPNSHCINTLGSYRCGQCKSGYKGDQIRGCQAER S---CRSRA-LNPCSVHARCIE---ERRG-EVTCICGIGWAGDGYICGKDVDIDGYPNEE LSCPA----ESCRKDNCKFVPNSGQEDADDDGIGDACDEDADGD-GIPNEQDNCVLTPNV NQRNS-DE---DIFGDACDNCRSVLNNDQRDTDGDGKGDACDDDMDGDGIKNLLDNCQRI PNQDQEDKDNDGVGDACDSCPTVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT IINSSQLDTDKDGLGDECDEDDDNDGIPDLLPPGPDNCRLVPNPGQEDDNGDGVGDVCES DFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDPRNVGWKDKVSYRWFL QHRPQIGYIRARFYEGSDLVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQAQQFGVGDI------------------------------------------ >XP_008974044.2 thrombospondin-4 isoform X1 [Pan paniscus] ----------------------------------------MLAPR-------GA---AVL ---------LL-HLVLQRW----------------LAA-----------------GAQAT PQ----------VFDLLP-------------------------------SSSQRLNPGAL LPVLTD-PALNDLYVISTFKLQT---KSSATIFGLYSSTDNSK-------YFEFTVMG-R LNKAILRYLK----NDGKVHLVVFNNL-QLA--DGRRHRILLRLSNLQRG-AG------- -----SLELYLDCIQVDSIH------NLPRAFAGPSQ----KPETIELRTFQR------- -KPQDFLEELKLVVRGSLFQ-----------------------------VASL------- ---------------QDCFLQQSEPLAATGT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMTQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLKFQSPTP-STVVPPAPP-------------------- ---------------------------------------------AP------------- ------------------------------------------------------------ ------PT---------------------RPPRRCDSNPCFRGVQCTDSRD---GFQCGP CPEGYTGNGITCIDVDECK-Y-HPCYP---GVRCINLSPGFRCDACPVGFTGPMVQGVGI SF--AKSNKQVCTDIDECR---NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAER N---CRNPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLIHNV DQRNS-DK---DIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKF PNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICES DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRFDN------------------------------------------ >XP_003981157.1 thrombospondin-4 [Felis catus] ----------------------------------------MLAPR-------GA---AFL ---------LL-HLALQPW----------------LGA-----------------GAQAT PQ----------VFDLLP-------------------------------SSSQRLNPAVL QPILTD-PTLNEVYVISTFKLHS---KSSSTILGLYSSVDGSK-------YFEFTVMG-R LNKAVLRYLK----NDGRIHLVVFNNL-HLA--DGRRHRVLLRLTNLRRG-TG------- -----SVELYMDCTQVDSVH------NLPRAFSGSSQ----SPESIELRTFQR------- -KAQDSLEELKLVVRGSLFQ-----------------------------VASL------- ---------------QDCFLQQSEPLATTST----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMTQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLVPPASP-------------------- ---------------------------------------------APTTS---------- ------------------------------------------------------------ ------ST---------------------PPVRRCDSNSCFRGVRCTDTRD---GFQCGP CPEGYTGNGITCSDIDECK-Y-HPCYP---GVRCVNLAPGFRCDACPMGFTGPMVQGVGI SF--AKSNKQVCTDIDECQ---NGACVLNSICINTLGSYRCGPCKPGYTGDQTTGCKTER S---CRNPE-LNPCSVNAQCIE---ERQG-DVTCVCGIGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDDDADGD-GILNEQDNCVLTHNV DQRNS-DK---DIFGDACDNCRNVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCPKV PNRDQRDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDVVPPGPDNCRLVPNPAQEDSNSDGVGDICET DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRLDN------------------------------------------ >XP_027827293.1 thrombospondin-4 [Ovis aries] ----------------------------------------MLAPR-------GA---AFL ---------LL-HLALQPW----------------LGA-----------------GAQAA PQ----------VFDLLP-------------------------------SASQRLNPSVL QPILTD-PTLNELYVISTFKLQS---KSSATIFGLYSSADHSK-------YFEFTVMG-R LNKAVLRYLK----NDGRIHLVVFNNL-QLA--DGRRHRLLLRLTNLHRG-AG------- -----SVELFLDCTRVDSIH------NLPRAFSGLAQ----SPEAVELRTFQR------- -KAHDSLEELKLVVRGSLIQ-----------------------------VASL------- ---------------QDCFLQQSEPLATTNT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMSQLNQLLGEV KDLLRQQVKETTFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLIPVVPA-------------------- ---------------------------------------------AS------------- ------------------------------------------------------------ ------PT---------------------PPVRRCDSNPCFRGVRCTDTRD---GFQCGP CPEGYTGNGIACSDVDECK-Y-HPCYP---GVRCVNLAPGFRCDACPVGFTGPMLQGVGI NF--AKTNKQVCTDVDECR---NGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKMER N---CRDPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLTHNV DQRNS-DK---DIFGDACDNCRNVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCQKV PNSDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICEA DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRLDK------------------------------------------ >XP_004058683.1 thrombospondin-4 [Gorilla gorilla gorilla] ----------------------------------------MLAPR-------GA---AVL ---------LL-HLVLQRW----------------LAA-----------------GAQAT PQ----------VFDLLP-------------------------------SSSQRLNPGVL LPVLTD-PALNDLYVISTFKLQT---KSSATIFGLYSSTDNSK-------YFEFTVMG-R LNKAILRYLK----NDGKVHLVVFNNL-QLA--DGRRHRILLRLSNLQRG-AG------- -----SLELYLDCIQVDSIH------NLPRAFAGPSQ----KPETIELRTFQR------- -KPQDFLEELKLVVRGSLFQ-----------------------------VASL------- ---------------QDCFLQQSEPLAATGT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMIQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLKFQSPTP-STVVPPAPP-------------------- ---------------------------------------------AP------------- ------------------------------------------------------------ ------PT---------------------RPPRRCDSNPCFRGVQCTDGRD---GFQCGP CPEGYTGNGITCIDVDECK-Y-HPCYP---GVRCINLSPGFRCDACPVGFTGPMVQGVGI SF--AKSNKQVCTDIDECR---NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAER N---CRNPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLIHNV DQRNS-DK---DIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKF PNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICES DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRFDN------------------------------------------ >XP_021147870.1 LOW QUALITY PROTEIN: thrombospondin-4 [Columba livia] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MVTNFL QQALGD-STLDDVYLLSTFKLQP---KSTATVFGLYSSADNNK-------YFEFTVMG-R MNKVVLRYLK----SDGRLNSVIFSNI-HLA--DGKPHAVILWLSGLQQG-SS------- -----TMELYLDCLQVGAVQ------DMPKAFSALSL----RSSAVELRTFQE------- -KPQEALDELKLVTGGTLAE-----------------------------VGNL------- ---------------QDCFLQQIEP-VSQYT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQLMGQMMQMNQILGDV KDLLRQQVKETTFLRN-------------------------TIAECSFCI----KG---- -------------------LGTVNF----------PTQLP-------------------- ---------------------------------------------R-------------- ------------------------------------------------------------ -----------------------------RSKPKCEVNSCFRGVRCMETAE---GFQCGP CPEGLTGNGVTCSDIDECR-Y-SPCFP---GVRCVNTAPGFRCETCPPGYTGQTVQGVGL SY--AKNNKQICLDIDECQNGGLGLCVPNSHCINTLGSYRCGQCKPGYTGDQVRGCQAER S---CRNRA-LNPCSVHARCIE---EKRG-EVTCICGIGWAGDGYICGKDVDIDGYPNEE LSCSA----ENCRKDNCRFVPNSGQEDADGDGIGDACDDDADGD-GIPNEQDNCVLAPNV NQRNG-DQ---DIFGDACDNCRNVLNNDQRDTDGDGKGDACDDDMDGDGIKNLLDNCQRI PNQDQEDMDNDGVGDACDSCPTISNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNCPT IINSSQLDTDKDGLGDECDEDDDN------------XCRLVPNPGQEDDNGDGVGDICES DFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDPRNVGWKDKVSYRWFL QHRPQIGYIRARFYEGSDLVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQAQQFGVGDI------------------------------------------ >XP_017909157.1 PREDICTED: thrombospondin-4 [Capra hircus] ----------------------------------------MLAPR-------GA---AFL ---------LL-HLALQPW----------------LGA-----------------GAQAA PQ----------VFDLLP-------------------------------SASQRLNPSVL QPILTD-PTLNELYVISTFKLQS---KSSATIFGLYSSADHSK-------YFEFTVMG-R LNKAVLRYLK----NDGRIHLVVFNNL-QLA--DGRRHRLLLRLTNLHRG-AG------- -----SVELFLDCTRVDSIH------NLPRAFSGLAQ----SPEAVELRTFQR------- -KAHDSLEELKLVVRGSLIQ-----------------------------VASL------- ---------------QDCFLQQSEPLATTNT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMSQLNQLLGEV KDLLRQQVKETTFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLIPVVPA-------------------- ---------------------------------------------AS------------- ------------------------------------------------------------ ------PT---------------------PPVRRCDSNPCFRGVRCTDTRD---GFQCGP CPEGYTGNGIACSDVDECK-Y-HPCYP---GVRCVNLAPGFRCDACPVGFTGPLLQGVGI NF--AKTNKQVCADVDECR---NGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKMER N---CRDPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLTHNV DQRNS-DK---DIFGDACDNCRNVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCQKV PNSDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICEA DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRLDK------------------------------------------ >XP_025057186.1 thrombospondin-4 [Alligator sinensis] ----------------------------------------MKRSFKNAFGKKGTFHELAL P-DLTNEKWLLKEAKEALWQVAAARARWPEPPRPAQPP-----------------GAQPG PQ----------VFDLLS-------------------------------YPNQRLVRNFL QQAFAD-STLNEVYLLSTFKLQP---KSTATIFGLYSSLENSK-------YFEFTVIG-R LNRAALRYLR----SDGRLNSVIFSNI-QLA--DGKRHAVLLRLSGLHRG-SS------- -----KVEMYVDCMQVDVIQ------DLPKAFSGLSQ----SPEFVELRTLQR------- -KAQDILDELKLVVRGSLSQ-----------------------------VGSL------- ---------------QDCFLQQIEP-AVQYT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQLMSQMMQMNQILGDV KDLLRQQVKETTFLRN-------------------------TIAECQAC------G---- -------------------LGPMDF----------PTSPP-------------------- ---------------------------------------------R-------------- ------------------------------------------------------------ -----------------------------PPKPRCEATSCFRGVRCTETAD---GFQCGP CPEGFTGNGVTCSDTDECR-Y-NPCFP---GVQCVNSVPGFKCEPCPPGYTGQTVQGVGI NY--AKNNKQVCSDIDECNNGGNELCVPNSHCINTLGSYRCGPCKTGYVGDQIKGCNAEK S---CRNRA-LNPCSIYAQCIE---ERQG-DVSCVCGIGWAGDGYICGKDVDIDGYPNED LTCSA----DTCRKDNCRFVPNSGQEDADGDGIGDACDDDADGD-GIPNEQDNCVLIPNV NQKNS-DQ---DIFGDACDNCRTVPNNDQKDTDGDGKGDACDDDMDGDGIKNLLDNCQRI PNQDQKDKDNDGVGDACDSCPHISNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSSQLDTDKDGLGDECDDDDDNDGIPDLIPPGPDNCRLVPNPGQEDENTDGVGDICES DFDQDTVIDQIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQAAP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWFL QHRPQMGYIRARFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFEEFQAQQFGVGDI------------------------------------------ >XP_014449911.1 PREDICTED: thrombospondin-4 [Alligator mississippiensis] ----------------------------------------M-SPR-------GA---ACL ---------LL-QLLLQLW----------------PGR-----------------GAQPG PQ----------VFDLLS-------------------------------YPNQRLVRNFL QQALAD-PTLNEVYLLSTFKLQP---KSTATIFGLYSSLENSK-------YFEFTVIG-R LNRAALRYLR----SDGRLNSVIFSNI-QLA--DGKRHAVLLRLSGLHRG-SS------- -----KVEMYVDCMQVDVIQ------DLPKAFSGLSQ----SPEFVELRTLQR------- -KAQDILDELKLVVRGSLSQ-----------------------------VGSL------- ---------------QDCFLQQIEP-EVQYT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQLMSQMMQMNQILGDV KDLLRQQVKETTFLRN-------------------------TIAECQAC------G---- -------------------LGPMDF----------PTSPP-------------------- ---------------------------------------------R-------------- ------------------------------------------------------------ -----------------------------PLKPRCEATSCFRGVRCTETAD---GFQCGP CPEGFTGNGVTCSDTDECR-Y-NPCFP---GVQCVNSVPGFRCEPCPPGYTGQTVQGVGI NY--AKNNKQVCSDIDECNNGGNELCVPNSHCINTLGSYRCGPCKTGYMGDQIKGCNAEK S---CRNQA-LNPCSIYAQCIE---ERQG-DVSCVCGIGWAGDGYICGKDVDIDGYPNED LTCSA----DTCRKDNCRFVPNSGQEDADGDGIGDACDDDADGD-GIPNEQDNCVLIPNV NQKNS-DQ---DIFGDACDNCRTVPNNDQKDTDGDGKGDACDDDMDGDGIKNLLDNCQRI PNQDQKDKDNDGVGDACDSCPHISNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSSQLDTDKDGLGDECDDDDDNDGIPDLIPPGPDNCRLVPNPGQEDENTDGVGDICES DFDQDTVIDQIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQAAP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWFL QHRPQMGYIRARFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFEEFQAQQFGVGDI------------------------------------------ >XP_020725677.1 thrombospondin-4 [Odocoileus virginianus texanus] ----------------------------------------MLAPR-------GA---TVL ---------LL-HLALQPW----------------LGA-----------------GAQAT PQ----------VFDLLP-------------------------------SASQRLNPSVL QPILTD-PTLNELYVISTFKLQS---KSSATIFGLYSSADHSK-------YFEFTVMG-R LNKAVLRYLK----NDGRIHLVVFNNL-QLA--DGRRHRLLLRLTNLHRG-AG------- -----SVELFLDCTRVDSIH------NLPRAFSGLAQ----SPEAVELRTFQR------- -KAHDSLEELKLVVRGSLIQ-----------------------------VASL------- ---------------QDCFLQQSEPLATTNT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMSQLNQLLAEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLVPAVPA-------------------- ---------------------------------------------AS------------- ------------------------------------------------------------ ------PT---------------------PAPRRCDSSPCFRGVRCTDTRD---GFQCGP CPEGYTGNGVACSDVDECK-Y-HPCYP---GVRCVNLAPGFRCDACPVGFTGPMMQGIGI NF--AKTNKQVCTDIDECR---NGACVLNSICVNTLGSYRCGPCKPGYIGDQMRGCKMER N---CRDPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLTHNV DQRNS-DK---DIFGDACDNCRNVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCQKV PNRDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDRNSDGVGDICEA DFDQDQIIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRLDK------------------------------------------ >XP_040196487.1 thrombospondin-4 [Rana temporaria] ----------------------------------------M-PKR-------KN---LLL ---------TL-LVLLELY----------------WEC-----------------EAQAN YQ----------VLDLLS-------------------------------PAVQRQVTNYL QQALNN-PSMNEVYVLSTFKLQP---KSTVTLFGLYSTKENSR-------YFEFTVMG-R LNKASLRYLK----SDGRLNSVIFNNI-ELA--DGKQHSLLLHLSGLHRG-PS------- -----AAELYLDCIQVDAIK------DLPRPLTGLNL----NTGSVQLKTLQK------- -KGQDSMDELKLVMGGSLTQ-----------------------------VASI------- ---------------QECFMQQSEP--GQYA----------------------------- ------------------------------------------------------------ ----------GD-----------------------------VSRQLLGQISQLNQLLGEL RDVMRQQVKETMFLRN-------------------------TVSECQAC------G---- -------------------LTPDY---------PLPTQPP-------------------- ---------------------------------------------KPK------------ ------------------------------------------------------------ ------PTT--------------------PPKPRCAATSCFQGVRCIDTES---GFQCGP CPEGYTGNGIICTDTDECR-L-NPCFP---GVRCINTIPGFRCESCPPGYTGPIVQGVGT TY--ARQNKQICLDINECENGRNGGCVTNSICTNTMGSFRCGPCKSGFVGDQIKGCKAEK S---CSIRG-SNPCHAGAQCIE---EKGG-EVTCICSVGWAGNGYFCARDTDIDGYPDEA LLCSD----PSCKKDNCIYVPNSGQEDTDKDGIGNSCDDDADGD-GIMNEQDNCVLVANI NQKNS-DQ---DIFGDACDNCRFKLNNDQRDTDNDGEGDACDDDMDGDGIKNFLDNCQRV PNVDQKDKDGDGVGDACDSCPDIVNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSSQLDTDKDGLGDECDDDDDNDGIPDLIPPGPDNCRLVPNPGQEDDNNDGVGDICES DFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWIVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAIKSKTGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWFL QHRPQDGYIRARFFEGSELVADSGVTVDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQAFQAQQFTS--------------------------------------------- >XP_043326699.1 thrombospondin-4 [Cervus canadensis] ----------------------------------------MLAPR-------GA---TVL ---------LL-HLALQPW----------------LGA-----------------GAQAT PQ----------VFDLLP-------------------------------SASQRLNPSVL QPILTD-PTLNELYVISTFKLQS---KSSATIFGLYSSADHSK-------YFEFTVMG-R LNKAVLRYLK----NDGRIHLVVFNNL-QLA--DGRRHRLLLRLTNLHRG-AG------- -----SVELFLDCTRVDSIH------NLPRAFSGLAQ----SPEAVELRTFQR------- -KAHDSLEELKLVVRGSLIQ-----------------------------VASL------- ---------------QDCFLQQSEPLATTNT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMSQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLVPVVPA-------------------- ---------------------------------------------AS------------- ------------------------------------------------------------ ------PT---------------------PPVRRCDSNPCFRGVRCTDTRD---GFQCGP CPEGYTGNGIACSDVDECK-Y-HPCYP---GVRCVNLAPGFRCDACPVGFTGPMMQGVGI NF--AKTNKQVCTDIDECR---NGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKMER N---CRDPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLTHNV DQRNS-DK---DIFGDACDNCRNVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCQKV PNRDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDRNSDGVGDICEA DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRLDK------------------------------------------ >KAB0343956.1 hypothetical protein FD754_020882 [Muntiacus muntjak] ----------------------------------------MLAPR-------GA---TVL ---------LL-HLALQPW----------------LGA-----------------GAQAT PQ----------VFDLLP-------------------------------SASQRLNPSVL QPILTD-PTLNELYVISTFKLQS---KSSATIFGLYSSADHSK-------YFEFTVMG-R LNKAVLRYLK----NDGRIHLVVFNNL-QLA--DGRRHRLLLRLTNLHRG-AG------- -----SVELFLDCTRVDSIH------NLPRAFSGLAQ----SPEAVELRTFQR------- -KAHDSLEELKLVVRGSLIQ-----------------------------VASL------- ---------------QDCFLQQSEPLATTNT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMSQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLVPVAPA-------------------- ---------------------------------------------AS------------- ------------------------------------------------------------ ------PT---------------------PPVRRCDSNPCFRGVRCTDTRD---GFQCGP CPEGYTGNGIACSDVDECK-Y-HPCYP---GVRCVNLAPGFRCDACPVGFTGPMMQGVGI NF--AKTNKQVCTDIDECR---NGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKMER N---CRDPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLTHNV DQRNS-DK---DIFGDACDNCRNVVNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCQKV PNHDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDRNSDGVGDICEA DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRLDK------------------------------------------ >KAB0375369.1 hypothetical protein FD755_013861 [Muntiacus reevesi] ----------------------------------------MLAPR-------GA---TVL ---------LL-HLALQPW----------------LGA-----------------GAQAT PQ----------VFDLLP-------------------------------SASQRLNPSVL QPILTD-PTLNELYVISTFKLQS---KSSATIFGLYSSADHSK-------YFEFTVMG-R LNKAVLRYLK----NDGRIHLVVFNNL-QLA--DGRRHRLLLRLTNLHRG-AG------- -----SVELFLDCTRVDSIH------NLPRAFSGLAQ----SPEAVELRTFQR------- -KAHDSLEELKLVVRGSLIQ-----------------------------VASL------- ---------------QDCFLQQSEPLATTNT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------FNRQFLGQMSQLNQLLGEV KDLLRQQVKETSFLRN-------------------------TIAECQAC------G---- ---------------------PLSFQSPTP-NTLVPVPPA-------------------- ---------------------------------------------AS------------- ------------------------------------------------------------ ------PT---------------------PPVRRCDSNPCFRGVRCTDTRD---GFQCGP CPEGYTGNGIACSDVDECK-Y-HPCYP---GVRCVNLAPGFRCDACPVGFMGPMMQGVGI NF--AKTNKQVCTDIDECR---NGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKMER N---CRDPE-LNPCSVNAQCIE---ERQG-DVTCVCGVGWAGDGYICGKDVDIDSYPDEE LPCSA----RNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQDNCVLTHNV DQRNS-DK---DIFGDACDNCRNVVNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCQKV PNHDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDRNSDGVGDICEA DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFQTQNFDRLDK------------------------------------------ >NP_001087096.1 thrombospondin 4 S homeolog precursor [Xenopus laevis] ----------------------------------------MPRGK-------GL---CLF ---------LQ-MLLLHLY----------------GVC-----------------QAQPN YQ----------VFDLLS-------------------------------VSVQRQVTSFL QNALSN-PSMNEVYVLSTFKLQP---KSTVTLFGLYSTSDNSR-------LFEFTVIG-R LNKASLRYLR----SDGKLHIVFFNNI-DLA--DGKQHTLLLHMSGLHRG-SS------- -----FADLYLDCHPVAGVK------DLPRPLSGISH----NTGSVLLRTLQK------- -RGQDSMDELKLVMGGTLSQ-----------------------------IGSI------- ---------------QECFMQQSEP--GQQT----------------------------- ------------------------------------------------------------ ----------GD-----------------------------VSRQLIGQITLMTQLLGEL RDVMRQQVKETMFLRN-------------------------TISECQAC------G---- -------------------LGPDD---------PLPTEAP-------------------- ---------------------------------------------KRQ------------ ------------------------------------------------------------ ------TTTA-------------------PPKPQCDASSCFRGVRCINAET---GFQCGP CPEGYTGNGVICTDVDECQ-L-NPCFP---GVRCINTSPGFKCESCPPGYTGSTIQGIGI NF--AKQNKQVCTDINECENGRNGGCTSNSLCINTMGSFRCGACKPGYVGDQIKGCKPEK S---CRH-G-QNPCHASAQCSE---EKDR-DITCTCSVGWAGNGYLCGKDTDIDGYPDEA LPCPD----KNCKKDNCKYVPNSGQEDTDKDKIGDACDEDADGD-GILNEQDNCVLAVNI DQKNS-DQ---DIFGDACDNCRLTLNNDQRDTDNDGKGDACDDDMDGDGIKNILDNCQRV PNVDQKDKDGDGVGDACDSCPDIINPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNCPT VINSSQLDTDKDGIGDECDDDDDNDGIPDTVPPGPDNCRLVPNPGQEDDNNDGVGDVCEA DFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWIVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTLTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKSGPGEHLRNALWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWFL QHRPQVGYIRARFYEGTELVADSGVTVDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQAFQAQQFSS--------------------------------------------- >XP_030290980.1 thrombospondin-4-B-like [Sparus aurata] ----------------------------------------MGVWT-----------ALIL ---------AS-QLLLKLC-----------------------------------LHVEAQ AL----------VYDLLT---------------------------------SPDCLPDLL QGGLAG-QGVNEAFILATFKLQP---KTGTSVFGLYNPRDNSK-------YFEFTVMG-K LNRAVLRYLR----SDNRMSSVTFNNL-VLA--DGQQHRLLFHLRGMQQQGPG------- -----GVELHLDCRLVETVR------DLPAAFQGLPA----GYGMVELKTMQA------- -RDQESLDELKLVVGDSFEN-----------------------------VASL------- ---------------QDCHFQQRDS--VQTL----------------------------- ------------------------------------------------------------ ----------GV-----------------------------NTKQLSNQMLELTKVINEL KDVLIQQVKETSFLRN-------------------------TISECQAC------G---- -------------------LGGSE------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------PVKPKCVSGVCFRDDMCQETAE---GVECGP CPDGYTGDGFNCDDVDECQ-F-NPCFP---GVKCVNTAPGYRCDACPLGYSGLAVEGVGV LF--AQTNKQVCDDVDECKGPNNGGCTENSQCHNSVGSYHCGSCKSGFTGDQVKGCKPEL S---CGNSL-TNPCDINAQCIP---ERDG-TITCQCGIGWAGNGYLCGKDTDIDGYPDEK LKCKD----PNCKKDNCVYVPNSGQEDADRDGYGDTCDDDADGD-GIPNEQDNCWLKPNV DQRNS-DK---DSHGDACDNCRAVENPDQRDTDGDGKGDACDDDMDGDGLKNFLDNCQRV QNRDQLDRDGDGVGDACDSCPDIPNPNQSDIDNDLVGDSCDTNQDSDGDGHQDTKDNCPL VINSSQLDTDKDGLGDECDDDDDNDGIPDTLPPGPDNCRLVPNPDQIDDNNDGVGDVCES DFDQDKVIDRIDNCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSQSGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYL QHRPQVGYIRARFYEGTELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFSTQHGVDSL------------------------------------------- >XP_015798465.1 PREDICTED: thrombospondin-4-B isoform X1 [Nothobranchius furzeri] ----------------------------------------MLVWT-----------TLIL ---------AS-QLL----------------------------------------NVEAQ AL----------VYDLLT---------------------------------SPDCLPDLL QGGLAE-QGVNDAFILTSFKLLP---KTGTTVFSLYNPRDNSK-------YFEFTVMG-K LNRAVLRYLR----SDKRMSSITFNNL-VLA--DGQQHRLLFHLKGLQQQEPG------- -----GVELHLDCRLVETVR------DLPAAFRGLPA----GYGLVELKTMQA------- -RAQESLDELKLVVGDSFEN-----------------------------VASL------- ---------------QDCHFQQRDS--VQTL----------------------------- ------------------------------------------------------------ ----------GV-----------------------------NTKQLSNQMQELTKVINEL KDVLIQQVKETSFLRN-------------------------TISECQAC------GQNIH ------------------SLGGTE------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------VVKPSCGPGVCFRDDMCIETAD---GVECAP CPDGYTGDGFNCDDVDECQ-F-NPCFP---GVKCVNTAPGFRCDACPLGYIGLPVEGVGI VF--AQTNKQVCDDVDECKGPDNGGCTQNSHCHNSVGSFYCGSCKTGFTGDQVKGCEPEL S---CGNSL-TNPCDVNAQCVR---ERDG-SISCQCGIGWAGNGYMCGKDTDIDGYPDEK LKCKD----PNCKKDNCIYVPNSGQEDVDRDGLGDTCDDDADGD-GIPNEQDNCWLKPNV DQRNS-DK---DSHGDACDNCRLVENPDQRDTDEDGKGDACDDDMDGDGLANFLDNCQRV QNRDQLDRDGDGVGDACDSCPDIPNPNQSDVDNDLVGDSCDTNQDSDGDGHQDTKDNCPF VINSSQLDSDKDGLGDECDDDDDNDGIPDLLPPGPDNCRLVPNPEQVDDNNDGVGDICES DFDQDKVIDRIDNCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKSGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYL QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFSAQHAVDSI------------------------------------------- >XP_004074610.1 thrombospondin-4-B [Oryzias latipes] ----------------------------------------MDMWR-----------TLLL ---------TS-QLLLNLC-----------------------------------LHVEAQ AL----------VYDLLT---------------------------------SPDCLPDLL QGGLIE-QGVNEAFILTSFKLQP---KSGTTVFSLYNPRDNSK-------YFEFTVMG-K LNRAVLRYLR----SDRRMSSVTINNL-VLA--DGQKHRLLFHLRGLQQQGPG------- -----GLELHLDCRLVETVR------DLPAAFQGLPT----GYGTVQLKTMQP------- -REQESLDELKLAVGDSFES-----------------------------VASL------- ---------------QDCHFQQRDS--VQTL----------------------------- ------------------------------------------------------------ ----------GV-----------------------------NTKQLSNQMMELTKVINEL KDVLIQQVKETSFLRN-------------------------TISECQAC------D---- -------------------LGGSE------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------VVKPKCSPGVCFRDDMCIETAN---GVECAA CPDGYTGDGFNCDDVDECQ-F-NPCYP---GVKCVNTAPGFRCDACPLGYIGLPVEGVGI VF--AQTNKQVCDDIDECKGPSNGGCPANSNCENSMGSYHC-SCKTGFIGDPVKGCKPEV S---CGNSL-TNPCHANASCVL---ERDG-SISCQCGIGWAGNGYLCGKDTDIDGYPDEK LKCKD----AHCRKDNCIYVPNSGQEDADRDGQGDACDEDADGD-SIPNELDNCWLKPNV DQKNS-DS---DSHGDACDNCRLAKNPDQRDTDGDGKGDACDDDMDGDGLKNFLDNCQRV QNRDQLDRDGDGVGDACDSCPDIPNPNQSDIDSDLVGDSCDTNQDSDGDGHQDTKDNCPY VINSSQVDSDKDGLGDECDDDDDNDGIPDVLPPGPDNCRLVPNPDQMDDNDDGVGDVCES DFDQDKVIDRIDICPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNHQVRLLWKDPRNVGWKDKVSYRWYL QHRPQVGYIRARFYEGTELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP EDFQEFRAQHAVDPI------------------------------------------- >XP_043732019.1 thrombospondin-3 [Cervus elaphus] ----------------------------------------METQE-----LRGA------ ------------LALLLLC----------------TFA-----------------SASQD LQ----------VIDLLT-------------------------------VGESRQMIAVV EKIRTALLTTGDIYLLSTFRLPP---KQGGVLFGLYSRQDNTR-------WLEASVVG-K INKVLVRYQR----EDGKVHAVNLQQA-GLA--DGRTHTALLRLRGPSKP-SP------- -----ALQLYVDCKLGDQHA------GLPALAPIPPA----EVSGLEIRTGQKAYL---- -RMQGFVESMKMILGGSMAR-----------------------------VGAL------- ---------------SECPFQGDESIHSAVTNA--------------------------- ------------------------------------------------------LHSIL- ----------GE-----------------------------QTKALVTQLTLFNQILVEL RDDIRDQVKEMSLIRN-------------------------TIMECQVC------G---- -------------------FH--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------EQRSHCSPNPCFRGVDCMEVYEY-PGYRCGP CPPGLQGNGTHCTDINECA-HADPCFP---GSSCINTMPGFHCEACPRGYKGTRVSGVGI DY--ARASKQVCNDVDECNDGNNGGCDPNSVCTNTVGSFKCGPCRLGFVGNQSQGCSPAR T---CHSPA-HSPCHVHAHCLF---ERNG-AVSCSCNVGWAGNGNVCGPDTDIDGYPDQA LPCMDNN--KHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGD-GIKNVEDNCRLFPNK DQQNS-DT---DSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKV PNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQ LPNSSQLDSDNDGLGDECDGDDDNDGVPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCED DFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS DPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATP FRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGNTPDQVRLLWTDPRNVGWRDKTSYRWQL LHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVP EDFEPFRRQLLQGRV------------------------------------------- >XP_039274396.1 cartilage oligomeric matrix protein-like [Styela clava] ----------------------------------------MDFYS-----------VLVF ---------IA-SFIVGIE----------------SIK-----------------KSSMF MS----------EVDLLRA------------------------------ARSEKSAIRVT EKVARTLTKAHTISLAFELKVPP---EEFVSVFAIYEKTGPRK-------YFEITVNG-R QDKVSIKSRDESDADDDELHVTSFRKV-GIA--NGQWHTMLIHFVITDSG-VA------- -----ETHFILDCAEKGRAEHPWIADQIRKSRNSTLIVKLGTKSTIDIKTHMR------- -KAVLLHDEQLPIVRRNYGG-----------------------------YCTQ------- ---------------ADMGIGSDPTLLNMMNN---------------------------- ------------------------------------------------------------ ----------FE-----------------------------PVSELIIQISDLASVLRDI HAGMKAQAIETKELRR-------------------------TLQQCSACT-----G-EKS LYSQ-----------------PTQSVSPTQ-GRFQVTEPP-------------------- ---------------------------------------------QPSII---------- ---------------------------KVEE----------------------------- ------PTE-------------------PPVIRKCSSNPCDSQVECEDTED---GFTCGR CPSGFTGNGIHCDDIDECETSFDPCSA---IAGCINTQGGYYCNLCPEGGFEQSYKEIEV AE--RIIQKQVCTDIDECKV-DNGGCAEFSKCINTAGSYKCGACIPGYHGNQTSGCVKVR Q---CSDGA-LNPCDVNAECLV---INTAEEYACECNAGYSGNGYVCGLDGDLDGYPNEQ MPCNV----KNCRQDNCPEVPNSGQEDSDLDGLGDACDSDADDD-GISNDEDNCVLVPNK DQQNS-DS---DLFGDACDNCPNANNPQQLDHDDNGKGDECDTDIDGDGIGETLENCPFV PNVSQDDMDGDSVGDACDNCPTMSNPMQSDSDHDSIGDVCDTNTDSDGDGRQDNMDNCPH VLNCAQLDTDNDGKGDACDEDDDNDGIPDY-GKQTDNCRLINNPNQLDDDGDNIGDACEN DQDGDGVVDWKDVCPYNRDISVTDFRSYQKVMLDPD-ESEVEPSWIVANEGMEITQKTNS DPGLLVGLDSFDGVDFSGTFFVNTASDDDYAGFLFSYQSSRKFYVVMWKQTSQEFWDDEP FRALALSGLHIKAVDSATGPGPDLRNALWHSGDTPNQVRTIWSDPNNVGWKDKTAYRWEL KHRPETGYIRLKFYEVNKLVADTGAIIDNTVKGGRLGVFCFSQERIIWSHLKYKCNEAYP EDY------------------------------------------------------- >XP_030832707.1 cartilage oligomeric matrix protein isoform X1 [Strongylocentrotus purpuratus] ----------------------------------------MQFGTC----------SIAF ---------LL-MLSVTSSQIPVSMG---------VEADLFD---GFGIYNSRIPGVSPA PQENSNIYGDAFFFNGISI------------------------------RYPIIANQEFF KKFAKEMRKNEDVYFVIRSRLAP---RHHGVLFGVYSSNYYSQDTFRTPLRFELSYNGTN GGKLVLKYR-----VGDQQRQAEFPNL-LVV--DGDWHTIILQFH-TERS-ST------- -----TLTLYVDCRLANQMK---IGDKLSRVFSRTVI------DGSEMRLGQAGYGMTAN -PLKGTIQNVRFMYGGPIGD-----------------------------VLHS------- ---------------LSCSLSTEPKPLDADG----------------------------- ------------------------------------------------------------ ----------WP-----------------------------GATILMDAFQSLSSTLMVL KNGMDDQTREIRHLRN-------------------------TLENCRMCE-----R-TDY FTSG-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------PQT--------------------IITHGCSSNPCFPDVMCFDEPDG-LGYRCGP CPAGYRGNGSYCYDINECI-EAYPCSD---VVECINLVPGFRCPPCPEGFIGLGLEGIGL EA--AVRNRQVCDDINECER-NNGDCVPNSYCINTRGSHICGDCKHGFEGNQTVGCKQKN T---CPNGE-RSPCHPKAKCII---HRNN-AYTCECIIGWAGDGYDCALDTDLDGYPDYA LPCTD----KHCRADNCVYIPNSGQENQDGDEMGDICDPDADND-GVPNGPDNCPLVANP DQVNSQDD---DPVGERCDNCPMTPNPKQIDTDADGKGDECDDDKDNDGILNIYDNCELV PNRMQDDTDGDGLGDACDNCPMQYNPDQNNTDSDLLGDICDNNEDSDDDGIQDNLDNCPK IPNNPQLDSDGDGRGDACDDDDDSDGVYDI----VDNCRIIHNPDQADYNQDGIGDMCDS DFDRDGVDDQYDACPENPNIFTTDLRTYQTVVLDPEGEAQVDPKWIVFDEGRQIMQTINS DPGLAISYQAFDGVDFEGTFFVNTRTDDDFAGFVFGYQDSASFYVLMWKQGPQTYWEASP FRAVGEPGFQLKVIKSDTGPGEMMRNALWHTGDTPGQSRLLWKDPNNHGWKDHVAYRWRV VHRPSIGLIRVKLYEADSLVADSGFLRDTTMRGGRIGLFCFSQEDIIWARITYKCNDDIP EGV-------------------------------------------TF---------- >CAE1249094.1 THBS2S [Sepia pharaonis] ------------------------------------------------------------ ------------------------------------------------------------ ------------MIALIA-------------------------------PADAQFRPLRK PEIGAAFMRYNELSLVGEIQLQSNRRRGRATLLRAENLAMNTK--------FDSYIDF-Q RAEVVINLKT----KDGREYAVRFLTG-VLS--ENKNKKIIIRFTNLQSN-SN------- -----GIQLFVNCMNAGRDN---TELPIRDVLMG-------NFSVQRHPAFKL------- -YGQASLKELLMMQGCEDTENIAPTRPSIPK---------PSLPSW---VGSIDPDRRFP D-IDIKRETHSREVSQDPFYTVDQIKTDRIH----------------------------- -------------------------------------------------------HSTI- ----------DS-----------------------------VKPELPNAIVELTIAIRDL QRDFQNQIRETHLLKE-------------------------TLKECQMCR-----G-TPP EPGNLR-----RCS-SNPCFQGVRCIDTEE-GFRCGSCPPGFYG---------------- ----DGKTC------------------------------------SAYLT---------- ---------------------------CNDRPCYPGVQ---------CSDTSSGFI---- --CGPCPTTLTGDGTV------HGCH---PTRVTCDSSPCFPGVMCTDQRT---GFHCGS CPTGYTGNGTYCEDLDECQ-FSRPCDR---RATCTNLSPGFTCTPCPQGYTSSPITGIGI LS--AQQTRQICQDIDECRS-NNGGCVPHSRCINTRGSFRCSECDPGYSGNQTVGCRRQI SN--CSNG---KECHKNARCIQ---RPESSTHECQCSIGYGGDGYYCSKDQDLDGIPDNA LPCGH----RKCRKDNCVSTPNSGQEDADGDGLGDACDPDADND-GIVNNPDNCPLVANP DQDDT-EDK-PDRKGDACDNCPTIPNPEQTDTDDDGMGDTCDPDADNDGIINAHDNCIRV KNADQRDTDGDGIGDACDNCPFVPNVKQLDSDADLTGDACDTNDDKDDDGVQDTNDNCPH IANSDQLDTDGDTLGDICDNDDDNDGVLDV----NDNCPLRMNPRQEDEDGNGVGDICEI DKDGDGSEDFIDVCPHNGNIYATDFRAYQTVILDPEGDSQIDPNWVILNQGAEIVQTMNS DPGIAISYTAFAGVDFSGTFYVNTEVDDDYAGFIFSYQDSSHFYVVMWKKNTQTYWHSTP FRAVAEPGIQLKLVNSSTGPGQYLRNALWHTGDTHDQVRLLWKDPRNEGWKERKAYRWEL IHRPYKGLIRILFFEETELIADSGNIYDFTLKGGRLGVFCFSQEMVIWSDLVYRCNDYIP PGLLEEEDYGYGQ--------------------------------------------- >XP_031556620.1 cartilage oligomeric matrix protein-like [Actinia tenebrosa] ----------------------------------------MKKSG-----------SIWY ---------LQ-SLLVLLS----------------MVL-----------------NTEAK IQ----------DFDLIKSFELGKGQITGLGRIEGYPGEPEEAYRFDRGLARLHLGPEFV SDLAEASRESKSLTITSNLKLDR---KSYGTLLSIETEGEGNL-------VFSLLFSCFS SCRISLYYP-----EGSLTSVTYFDKVPNIS--DGKWHKMVLHIQTNRMG-KH------- -----VVSLFMDCRSLGKKK---ISAGLDQLFPLSN-----EKVKYALRFAQRGASNSVY IPWKGSLQSVLLIFGVRSHS-----------------------------FANP------- ---------------VDCLTKSTRQILSGLTNKNNRHKYQPTVKVVTTQRRQTTSKDATT VKSTPTKPQKDGTT----------------KPQPSVRPITQKEKPTRNI---------VD IITSGETRF-GV-ADGSSPTTELVLTTSDEKLDYLVDMIRQLKKEQFHRESALRKTIEML RIDLNSQSQEVRYVRS-------------------------FLEHGGACK-----S-GSL IQQTGK-----RFDSIGTILPGRKT----------------------------------- ----DRQNP--------------------------------------------------- ------------------------------------------------------------ -----------------------------VAGGKCLQKPCFPFVECYETPDEGLGFRCGP CPPGFTGNGIRCEDVNECN-L-YPCSA---LTKCINLRPGYQCTPCPVGYLGNASMGLGV EM--ARKNKQVCEDINECANGRNGGCSIHSECINTQGSYRCGPCKPGYDGDSTRECKRVL F---CSNAPRANPCGKLAHCIP---RNDGRNYECKCKPGYGGDGVRCGKDSDMDGYPDRA LGCKG----PKCAKDNCREIPNSGQEDVDGDGTGDACEYDADGDRKPSKDQDNCPSVPNE DQQDT-DA---DGVGDACDNCQTVNNPDQEDTDKDGIGDACDVDIDGDGIINVLDNCPKV PNRDQKNTDGDPHGDACDNCKRGKNPDQADKDGDGIGDVCDFDQDYDRDGVDDRHDNCLR KPNAAQLDTDGDGLGDVCDSDDDNDGIPDY----KDNCRLVRNVDQKDSDNDGIGDACQG DYDNDGVPDAVDICPYNHNITKTDFSSFFNVNFDPLSKIKDYPQWKASKKGNEVYLRKNS NVGLFVATPKYEDIEFRGTMFVNTHQDDDIIGFAFGYQQYGHFFLLSWKRKEQMYWIVNP FRATAKTWLTLKRVKSSSVPSHGIRNALWHTAETRRHTKVLWQKRLTRGWKPKTAYRWEL NYTPSNGYLRLQMWVGTQQLMDTGILRDLEMRGGRLGFFSFSQGDIIWSDLQVRCVDGK- ---------------------------------------------------------- >XP_397221.5 cartilage oligomeric matrix protein isoform X1 [Apis mellifera] ----------------------------------------MRV----------------- ------------IITLIIT----------------------------------------- ------------IFFLVYV------------------------------VDSSITRDEDL EKNLRERWNDDFVIVFSNIKSKK---KQFQVMVEVLLTIKYEKS------KMVLMLDR-R AKRVILENIDEV--GHRVAQYINMDNL-NVNS-NFPSKNVIFLVHQSQPG---------- ----ARMAVYIDCIYRGVIP---LKKTFRELTNSE--------DNLLIEAFRERKSQVKV YPLARSMEALQEENCLSTLTDTNTESQELRSIDDNNNFETPSFNSARVNLRNK-----QN HHVHRSKEHNHDET-VDLFEDTDQIDLNSRQSNHNRH--------------------SVR DRSNRYKHENDRNKYLEFDQDFSSLMKRLQQPEYFNEPIQEKFEVLSNLNESDILNQPIN IYHKRVPRR-GD--IGIQSLDERVCL---------------TDNQIVKTLNELIGATKKI WREIELNRLETHRVLL-------------------------LIENCAACR-----E-PPP VPLTTTTPAPPSCSYKSPCFPGSECRDTPR-GPQCGACPPDYTG---------------- ----DGYRC-------------------------------------VKIT---------- ---------------------------CAHNPCFKGVR---------CYDQSDRYS---- --CGNCPIGYIGNG--------KHC----ELKNVCEPNPCYSEVQCDLISEP-PFYRCGV CPNGFTGNGSVCVDINECE-IAQPCSL---GVQCINLHPGFRCDPCPPGYTGTMIEGVGL EI--AMNRKQICQDINECEN-NNGGCDPYMECINMQGSYRCGACRAGFIGNQTVGCHPAH S---ICPDL-ITRCDVNAECVC---IDTN-VYSCRCRVGWTGDGLICGIDRDNDGIPDRN LHCRD----RHCRMDNCPLTPNSGQEDADRDGIGDACDPDADDD-GVLNSSDNCPFISNP GQEDN-DSDGPDLVGDICDNCPRVRNPKQEDTDDDGIGDACDPDIDNDGIPNNQDNCQKI KNQNQNDMDEDGIGDACDNCPYGYNPNQLDQDGDGVGDDCDNDNDRDRDGVQDDRDNCPD VANSGQNDDDHDGIGNECDNDMDNDGVPNS----NDNCPYVYNPDQRHTHNNFIGDACWH DYDNDTVKNIHDNCPNNSLIWATDFRKYTTIALDPFGTAQEDPVWVIHNDGAEIQQLVNS DPGIAIGPDIFSGVDFEGTFFVDDDGDDDFVGFVFSYQDNRRFYIVAWKKAHQPYWVPTP FRAVGDPGIYLKLVDSDTGPGEILRNSLWHNENTINQVKILWHDPKKIGWKERTSYRWQL LHRPKIGLIRFRLYQGKQLMADSGNVYDSTLKGGKLGVYCFSQEKITWSNLLYVCKETVP LSVWNDLPSNLRKEINVDINNE---------------------IKSQYSQKSIYYDSH >NP_001137802.1 thrombospondin, isoform F [Drosophila melanogaster] ----------------------------------------MNWTR--------------- ------------VLLIGLT----------------AL----------------------- ------------ALTFVD-------------------------------VASLSLDPVAS AELEQFIRKGDVVISTRHIRPRR---KLHISIEALFMIDFPMLKH-----KMSFFLDR-K QQRVTLDIS-----ANGATESRNFEIP-NIN------ETSTIRSLALQFS-KN------- -----RITLHVDCKASTHHD---IDMNLAKLYTQM--------DDPVIKLFRERKYPL-- -HFDGDMEHSLQRANCQKGNHRRGNRRMLRN---------KITERE---KNKKRDVRGWY E-PTIAREGVVDHRHQEVPTDVERGDIPVLN----------------------------- ------------------------------------------------------------ ----------GD-----------------------------CEDALARSLSDLLALVKLL REDVAHQRQEIAYLRM-------------------------LLENCAGCK-----N-PLT TDNQLR--IEPDCRSANPCYPGVECLDSAA-GPRCGHCPLGFIG---------------- ----DGKSC------------------------------------KPGVT---------- ---------------------------CAHHMCYPGVQ---------CHDTVNGAQ---- --CDSCPAGYEGDG--------RTC----SLRNPCLDTPCPSGAQCLQVGYP-PYFHCIS CPMGHEVNGTSCRDMNECL-LYDPCDE---LATCTNLSPGFQCSPCPVGFDGTHAHGYFA DYYSVDYRRQTCLDVDECRT-GFFRCPEHSTCINEIGSYRC-QCHEGYVTNGTYSCLDRS SVFMCPDG---TVCDRNAVCLR---MDNI-RHKCHCNVGWAGNGLICGRDTDVDGWPDQA IGCPE----LRCQRDNCPKLPNSGQEDADLDGHGDGCDDDADGD-NVQNSQDNCWLAYNT EQLDS-DG---DKVGDVCDNCVLKYNPRQLDTDEDGLGDECDGDIDNDSIPNALDNCPLL PNPSQSDVDNDGVGDACDNCPNLPNPDQKDRDMDFVGDACHRDIDGDDDGVPNSLDNCPM VSNSDQLDTDGDGTGDECDDDMDGDGIPNY----KDNCPLAKNPKQDDFNRNGKGDSCED DEDVDGVPNGMDNCPNNSMIHHTDFRTLQTIPLDPKGLSQADPNWVVHANGTEIVQTLNS DPGLAVGKDAFGGVDFDGTFYINDDTDDDYAGFVFSYQSSYKYYVVQWKKGTQTYWEPRP FTASAAPGIQIKLVNSTEGPGPMMRNSLWHEGNTDGEARLLWKDPKNIAWKERTSYRWSL VHRPAIGLIRLQMHEGNRLIFDSGNVFDSTLKGGRLGVFCFSQRMIIWSNLQYKCNNRVK PLIYNDLSDYLKTKVELQD--------------------------------------- >XP_038078580.1 thrombospondin-1-like isoform X1 [Patiria miniata] ----------------------------------------MPTRATM---ARLTYYVFAF -------GFLCSALHCQLT----------------KAYEEVDVMLASGI-SARTPGVRET KT----PEGGR-AFKVRPK------------------------------DRDLGTDQGSL ERLLRSMKADEGFILITVAYQDP---KNRGTLVSVDRTDGQVR-------GFGFHIDR-R NDEAVVQFAEFG-AGEPQESQVVFSPL-NIGKDDTELHTFVLDVR------GN------- -----LVTLYMDCQLIG------LKILPSSFYMNM------EPDNMKLRLGKGLPDRNNV LDFKGTLAVAKFAFQTSTTDVLISQGCEIE----------PVFSSSQISFGSS-----FP LPIGESEPSHIS---SDAAMPGGEGNVEQSTPNNNNH--------------------GDS --------GSFGNSGLSDSMSFGGAIPVPPGGSFSN--LNPGVPSSTGGTSGNVMPQPVP GTPPHLPTNMGYMHPNAAPTDDTMQ---------------GQCAYTCEQISNLNNQVQVL SDGYDDMWNKLEHFENQRPPEWPSQQGCWYMKTLYDDGDVFKVDKCKSCECRVEGG-LPT VECSLIKCQPGKC--ANPIIMEGDC---------CPTCPNDNLGWSDWAEWTSCSVTCGN GIQQRGRSCDRTQFECNGNDVETRVCYLDPCIEIVDGGWSNFTPWSCGVTCGNGTESRMR SCNSPRPKNGGKRCDGELDGAGREERPCGRDPCPVDGQWGQFSEFTPCTKTCDGGWQERY RFCDSPPPAHGGRDCVGSDTHRRMCNEWPCPIDACLSSPCFDGVECVSFTDG--RYECKD CPVGYTGNGILCQDINECLLVSDACFNFHGEHRCLNLIPGYTCRKCPIGYRGNQPSGMGV YH--AKRYKQQCIPINPCAE---------------------------------------- --------G-TSSCHIDARCIFYGPYSDP-QYGCKCKTGFAGDGVHCGYDSDLDGWPDEQ LDCEDHGDYTHCTRDNCASLPNSGQEDNDGDGKGDACDADDDDD-LVDDVADNCQFISNW QQFDI-DD---DGVGDVCDNCPFVSNTRQEDTDSDGDGDVCDYDIDEDGIYNEDDNCMYV ANARQLDFDEDGYGDVCDNCPDYGNPDQMDIDDDNVGDVCDTDRDVDNDGHQDDLDNCWN IANSDQADHDMDGIGDACDFDDDNDGIEDV----DDNCRLIFNPSQNDTNENGRGDACEY DNDGDGVTDLQDACPDNANIQRTDLSHFQLIKLDPEGSAQIDPHWIVRNRGQELVQTINS DPGLAIGYDEFNSVEFSGTFYVNTERDDDYAGFVFGYQSNHRFYSVMWKQVTQKYWEPMP TMSEATAGLQLKLINSTTGPGEYLRNALWHTGDTSDQVKLIWSDANKIGWKDFTAYRWIL THRPRTGYIRVTMYEGSKVLADSGALYDFTLQGGRIGLFCFSQEMVFFSDLQYKCLAEE- ----------------------------------------------------------
BMGE Cleaned alignment of selected proteins >sp|P35443|TSP4_HUMAN Thrombospondin-4 OS=Homo sapiens OX=9606 GN=THBS4 PE=1 SV=2 MLAPRHLVLQRWGAQATPQVFDLLPQRLNPGALLPALNDLYVISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLDGRRHRILLRLSNLQRGSLELYLDCIQVDSNLPRAFAGPSKPETIELRTFQRKPQDFLEELKLVVRGSLFQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLKFQSPTPSTVVPPAPPRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKHPCYPGVHCINLSPGFRCDACPVGFTGPVQGVGISFAKSNKQVCTDIDECR-NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFDN >tr|F1R1P9|F1R1P9_DANRE Thrombospondin-4-B OS=Danio rerio OX=7955 GN=thbs4b PE=3 SV=1 MAGTMSLILMLSSANAESIVYNLLTPDCLPDLLHQGVTELYILTTFRIQPGTGNTIFSLYNPRDNSKYFEFSVFGKANKAILRYLRRDGRMSAVTFNKLDGEKHRLLFHLKGLEVGGVELHLDCRLVETDLPAVFNGLNNHQAVELKTMQGKAQEGLEELKLAYGDSVEQDCH-TQSDS--NTKQLTTQMELTKVINELKDVLIQQVKETSFLRNTISECQACGAE---------------VVKPKCAPGVCFRDDMCIETAEGVECGPCPDGYTGDGYSCDDVDECQNPCFPGVRCVNMAPGFRCEACPLGFTGKLEGVGVAYAQTHKQVCDDIDECKGNGGCTANSICVNSVGSYQCGRCKTGFTGDQIRGCKPEKSCGNRLQNPCDPNAQCTETITCQCGIGWAGNGYLCGKDTDIDGYPDERLRCRDPTCRKDNCVTVPNSGQEDADGDGKGDACDPDADGDGILNEQDNCWLTPNINQQNSDSHGDACDNCVRVDNPDQRDTDSDGLGDACDDDMDGDGLKNFLDNCQRVKNRDQLDRDGDGVGDACDSCPDIPNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSKDNCPMVINSSQLDTDKDGIGDECDDDDDNDGIPDSLPPGPDNCRLVPNPEQIDDNNDGVGDICESDFDQDKVIDRIDNCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYLQHRPQVGYIRVRFYEGTELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFSTQHGMDPL- >NP_035712.1 thrombospondin-4 precursor [Mus musculus] MPAPRHLVLQPWSAQATPQVFDLLPQRLNPSALQPTLHEVYLISTFKLQSKSSATIFGLYSSSDNSKYFEFTVMGRLNKAILRYLKNDGKIHLVVFNNLDGRRHRVLLRLSNLQRGSVELYLDCAQADSNLPRAFSGLTNPESIELRTFQRKPQDFLEELKLVVRGSLFQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLSFQSPTPNTLVPIAPPRPTRHCDSSPCFRGVRCTDTRDGFQCGPCPDGYTGNGITCSDVDECKHPCYPGVRCVNLAPGFRCDACPVGFTGPVQGVGINFAKTNKQVCTDVDECQ-NGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCKTERSCRNPEQNPCSVHAQCIEDVTCVCGVGWAGDGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNIDQRNSDIFGDACDNCRMVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDDVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNNDGVGDICEADFDQDQVIDHIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQSFDRLDN >NP_058829.1 thrombospondin-4 precursor [Rattus norvegicus] MLAPRHLVLQPWGAQATPQVFDLLPQRLNPAALQPTLHELYVISTFKLQSKSSATIFGLYSSSDNSKYFEFTVMGRLNKAILRYLKDDGKIHLVVFNNLDGRRHRILLRLSNLQRGSVELYLDCVQVDSNLPRAFSGLTNPQAIELRTFQRKPQDFLEELKLVVRGSLFQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLSFQSPTPNTLVPIAPPRPTRRCDSSPCFRGVRCTDTRDGFQCGPCPDGYTGNGITCSDVDECKHPCYPGVRCTNLAPGFRCDACPVGFTGPVQGVGINFAKTNKQVCTDVDECR-NGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCRTERSCRNPEQNPCSVHAQCIEDVTCVCGVGWAGDGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNTDIFGDACDNCRGVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNNDGVGDICEADFDQDKVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQIQTFDRLDN >NP_001308478.1 thrombospondin-4 precursor [Gallus gallus] MGCERPLALQLCAAPPAPRVIDLLPKRVVTSFLQPTLNEVFLLSVFKLQPKSTTTIFDLYSPADDRQYFEFTVMGRMNKVVLRYLKNDGRLNSVIFSNVDGKPHAVILWLSGLQQETIELYLDCLQVGADLPKAFSTLLRSAAVELRTFLKKPEDTLDELKLVTGGTLAQDCFLQQIES-AFNRQLMNQMQMNQILGEVKDLLKQQVKETTFLRNTIAECQACTANF---------PTPLPHTKPKCEASSCFRGVRCMETAEGIQCGPCPEGLTGNGVTCSDVDECRSPCFPGVRCVNTAPGFRCETCPPGYTGQLQGVGLSYAKNNKQVCLDIDECQNHGVCVPNSQCINTLGSYRCGQCKSGYTGDQIRGCQAERSCRSRALNPCSVHARCIEEVTCICGIGWAGDGYICGKDIDIDGYPNEELSCPSESCRKDNCKFVPNSGQEDADDDGIGDACDEDADGDGIPNEQDNCVLTPNVNQRNSDIFGDACDNCRSVLNNDQRDTDGDGKGDACDDDMDGDGIKNLLDNCQRIPNQDQEDKDNDGVGDACDSCPTVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTIINSSQLDTDKDGLGDECDEDDDNDGIPDLLPPGPDNCRLVPNPGQEDDNGDGVGDVCESDFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDPRNVGWKDKVSYRWFLQHRPQIGYIRARFYEGSDLVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQAQQFGVGDI >XP_016808573.2 thrombospondin-4 [Pan troglodytes] MLAPRHLVLQRWGAQATPQVFDLLPQRLNPGALLPALNDLYVISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLDGRRHRILLRLSNLQRGSLELYLDCIQVDSNLPRAFAGPSKPETIELRTFQRKPQDFLEELKLVVRGSLFQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLKFQSPTPSTVVPPAPPRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKHPCYPGVRCINLSPGFRCDACPVGFTGPVQGVGISFAKSNKQVCTDIDECR-NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFDN >XP_038327488.1 thrombospondin-4 [Canis lupus familiaris] MPGPRHLVLQPWGAQGPPQVFDLLPQRLNPAVLKPTLNEVYVISTFKLHTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKIHLVVFNNLDGRRHRVLLRLTNLQRGSVELYLDCTQVDSNLPRAFSGSSSPDSIELRTFQRKAQDFLEELKLVVRGSLFQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLSFQSPTPNTLVPPAPPPPVRRCDSNSCFRGVRCTDTRDGFQCGPCPEGYTGNGITCSDIDECKHPCYPGVRCVNLAPGFRCEACPVGFTGPVQGIGISFAKSNKQVCTDIDECR-NGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCRTERSCRNPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCRYVPNSGQEDADGDGVGDACDEDADGDGILNEQDNCVLTHNVDQRNSDIFGDACDNCRNILNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCPRVPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNRDGVGDICETDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDS >NP_001029900.1 thrombospondin-4 precursor [Bos taurus] MLAPRHLALQPWGAQATPQVFDLLPQRLNPSVLQPTLNELYVISTFKLQSKSSATIFGLYSSADHSKYFEFTVMGRLNKAILRYLKNDGRIHLVVFNNLDGRRHRLLLRLTNLHRGSVELFLDCTRVDSNLPRAFSGLASPEAVELRTFQRKAHDSLEELKLVVRGSLIQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLSFQSPTPNTLMPVVPAPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGNGIVCSDVDECRHPCYPGVRCVNLAPGFRCDACPVGFTGPMQGVGISFAKTNKQVCTDIDECR-NGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKMERNCRDPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDDDADGDGILNEQDNCVLTHNVDQRNSDIFGDACDNCRNVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCQKVPNSDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICEADFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDK >XP_008260094.1 PREDICTED: thrombospondin-4 [Oryctolagus cuniculus] MRAPRHLALQPWGAQATPQVFDLLPERLSPGVLQPALHDLYVLSTFKLQTKSSAPIFGLYSTADNSRYFEFTVMGRLNKAILRYMKSDGKIHLVVFNNLDGRRHRLLLRLSNLQRGSVELYVDCTQVDSNLPRAFAALSSPESFELKTLQRKAQDFLEELKLVVRGSLFQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLSFQSPTPNTLVPPAPPPPRRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGSGITCSDVDECKHPCYPGVRCVNLAPGFRCEACPVGFTGPVQGAGISFATSNKQVCTDIDECA-NGACTPHSVCTNSVGSYRCGPCKPGYTGDQTRGCKPERSCRNPELNPCSPNAQCIQDVTCVCGVGWAGDGYVCGRDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADGDGLGDACDEDADGDSILNEQDNCVLTPNTDQRNSDIYGDACDNCRTVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPRVPNRDQRDKDGDGVGDACDSCPDISNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICETDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSQTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWFQPQVPLQRHHPRGLPGVPDPELRPPGE >XP_024103393.1 thrombospondin-4 [Pongo abelii] MLAPRHLVLQPWGAQATPQVFDLLPQRLNPGALLPALNDLYVISTFKLQTKSSATIFGLYSSTDNTKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLDGRRHRILLRLSNLQRGSLELYLDCIQVDSSLPRAFAGPSKPETIELRTFQRKPQDFLEELKLVVRGSLFQDCFLQQSEPLPFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLKFQSPTPSTVVPPAPPRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKHPCYPGVRCINLSPGFRCDACPVGFTGPVQGVGISFAKSNKQVCTDIDECR-NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFDN >XP_020940149.1 LOW QUALITY PROTEIN: thrombospondin-4 [Sus scrofa] MLATRHLALQPWGAQATPQVFDLLPQRLNPSVLQPTLNELYVISTFKLQTKSSATIFGLYSSADNSKYFEFTVMGRLNKAILRYLKNDGKIHLVVFNNLDGRRHRLLLRLTNLHRGSVELYLDCTQVDSNLPRAFAGLSSPGSVELRTFQRKAQDSLEELKLVVRGSLFQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLSFQSPTPNTLVAPAPPPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGNGVTCSDVDECRHPCYPGVRCVNLAPGFRCDACPVGFTGPVQGVGINFAKTNKQVCTDIDECR-NGACVLNSICVNTLGSYRCGPCKPGYIXDQMRGCKMERNCRNPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNMDQRNSDIYGDACDNCRNVLNNDQRDTDGDGKGDACDDDMDGDGIKNILDNCPKVANRNQQDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPGQEDSNSDGVGDICETDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDN >XP_019465735.1 thrombospondin-4 [Meleagris gallopavo] M-----------------RVIDLLSKREVTSFLQPTLNEVFLLSAFKLQPKSTATVFGLYSPADDKQYFEFTVMGRMNKVVLRYLKNDGRLNSVIFSNVDGKPHAVILWLSGLQQETIELYLDCLQVGADLPKAFSAQLRSAAVELRTFLKKPEDILDELKLVTGGTLAQDCFLQQIES-AASNQFI-QIVQKSCGGEYSSFCIK------------------MVNF---------PTPLPRSKPKCETSSCFRGVRCMETAEGIQCGPCPDGFTGNGVTCSDIDECHSPCFPGVRCVNTAPGFRCETCPPGYTGQLQGVGLSYAKNNKQVCLDIDECQNHGVCVPNSHCINTLGSYRCGQCKSGYKGDQIRGCQAERSCRSRALNPCSVHARCIEEVTCICGIGWAGDGYICGKDVDIDGYPNEELSCPAESCRKDNCKFVPNSGQEDADDDGIGDACDEDADGDGIPNEQDNCVLTPNVNQRNSDIFGDACDNCRSVLNNDQRDTDGDGKGDACDDDMDGDGIKNLLDNCQRIPNQDQEDKDNDGVGDACDSCPTVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTIINSSQLDTDKDGLGDECDEDDDNDGIPDLLPPGPDNCRLVPNPGQEDDNGDGVGDVCESDFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDPRNVGWKDKVSYRWFLQHRPQIGYIRARFYEGSDLVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQAQQFGVGDI >XP_008974044.2 thrombospondin-4 isoform X1 [Pan paniscus] MLAPRHLVLQRWGAQATPQVFDLLPQRLNPGALLPALNDLYVISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLDGRRHRILLRLSNLQRGSLELYLDCIQVDSNLPRAFAGPSKPETIELRTFQRKPQDFLEELKLVVRGSLFQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLKFQSPTPSTVVPPAPPRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKHPCYPGVRCINLSPGFRCDACPVGFTGPVQGVGISFAKSNKQVCTDIDECR-NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFDN >XP_003981157.1 thrombospondin-4 [Felis catus] MLAPRHLALQPWGAQATPQVFDLLPQRLNPAVLQPTLNEVYVISTFKLHSKSSSTILGLYSSVDGSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLDGRRHRVLLRLTNLRRGSVELYMDCTQVDSNLPRAFSGSSSPESIELRTFQRKAQDSLEELKLVVRGSLFQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLSFQSPTPNTLVPPASPPPVRRCDSNSCFRGVRCTDTRDGFQCGPCPEGYTGNGITCSDIDECKHPCYPGVRCVNLAPGFRCDACPMGFTGPVQGVGISFAKSNKQVCTDIDECQ-NGACVLNSICINTLGSYRCGPCKPGYTGDQTTGCKTERSCRNPELNPCSVNAQCIEDVTCVCGIGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDDDADGDGILNEQDNCVLTHNVDQRNSDIFGDACDNCRNVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCPKVPNRDQRDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDVVPPGPDNCRLVPNPAQEDSNSDGVGDICETDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDN >XP_027827293.1 thrombospondin-4 [Ovis aries] MLAPRHLALQPWGAQAAPQVFDLLPQRLNPSVLQPTLNELYVISTFKLQSKSSATIFGLYSSADHSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLDGRRHRLLLRLTNLHRGSVELFLDCTRVDSNLPRAFSGLASPEAVELRTFQRKAHDSLEELKLVVRGSLIQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETTFLRNTIAECQACPLSFQSPTPNTLIPVVPAPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGNGIACSDVDECKHPCYPGVRCVNLAPGFRCDACPVGFTGPLQGVGINFAKTNKQVCTDVDECR-NGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKMERNCRDPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNSDIFGDACDNCRNVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCQKVPNSDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICEADFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDK >XP_004058683.1 thrombospondin-4 [Gorilla gorilla gorilla] MLAPRHLVLQRWGAQATPQVFDLLPQRLNPGVLLPALNDLYVISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLDGRRHRILLRLSNLQRGSLELYLDCIQVDSNLPRAFAGPSKPETIELRTFQRKPQDFLEELKLVVRGSLFQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLKFQSPTPSTVVPPAPPRPPRRCDSNPCFRGVQCTDGRDGFQCGPCPEGYTGNGITCIDVDECKHPCYPGVRCINLSPGFRCDACPVGFTGPVQGVGISFAKSNKQVCTDIDECR-NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFDN >XP_021147870.1 LOW QUALITY PROTEIN: thrombospondin-4 [Columba livia] ---------------------------MVTNFLQSTLDDVYLLSTFKLQPKSTATVFGLYSSADNNKYFEFTVMGRMNKVVLRYLKSDGRLNSVIFSNIDGKPHAVILWLSGLQQGTMELYLDCLQVGADMPKAFSALSRSSAVELRTFQEKPQEALDELKLVTGGTLAQDCFLQQIEP-VFNRQLMGQMQMNQILGDVKDLLRQQVKETTFLRNTIAECSFCTVNF---------PTQLPRSKPKCEVNSCFRGVRCMETAEGFQCGPCPEGLTGNGVTCSDIDECRSPCFPGVRCVNTAPGFRCETCPPGYTGQVQGVGLSYAKNNKQICLDIDECQNLGLCVPNSHCINTLGSYRCGQCKPGYTGDQVRGCQAERSCRNRALNPCSVHARCIEEVTCICGIGWAGDGYICGKDVDIDGYPNEELSCSAENCRKDNCRFVPNSGQEDADGDGIGDACDDDADGDGIPNEQDNCVLAPNVNQRNGDIFGDACDNCRNVLNNDQRDTDGDGKGDACDDDMDGDGIKNLLDNCQRIPNQDQEDMDNDGVGDACDSCPTISNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNCPTIINSSQLDTDKDGLGDECDEDDDN------------XCRLVPNPGQEDDNGDGVGDICESDFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDPRNVGWKDKVSYRWFLQHRPQIGYIRARFYEGSDLVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQAQQFGVGDI >XP_017909157.1 PREDICTED: thrombospondin-4 [Capra hircus] MLAPRHLALQPWGAQAAPQVFDLLPQRLNPSVLQPTLNELYVISTFKLQSKSSATIFGLYSSADHSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLDGRRHRLLLRLTNLHRGSVELFLDCTRVDSNLPRAFSGLASPEAVELRTFQRKAHDSLEELKLVVRGSLIQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETTFLRNTIAECQACPLSFQSPTPNTLIPVVPAPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGNGIACSDVDECKHPCYPGVRCVNLAPGFRCDACPVGFTGPLQGVGINFAKTNKQVCADVDECR-NGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKMERNCRDPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNSDIFGDACDNCRNVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCQKVPNSDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICEADFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDK >XP_025057186.1 thrombospondin-4 [Alligator sinensis] MKRSFEAKEALWGAQPGPQVFDLLSQRLVRNFLQSTLNEVYLLSTFKLQPKSTATIFGLYSSLENSKYFEFTVIGRLNRAALRYLRSDGRLNSVIFSNIDGKRHAVLLRLSGLHRGKVEMYVDCMQVDVDLPKAFSGLSSPEFVELRTLQRKAQDILDELKLVVRGSLSQDCFLQQIEP-AFNRQLMSQMQMNQILGDVKDLLRQQVKETTFLRNTIAECQACPMDF---------PTSPPPPKPRCEATSCFRGVRCTETADGFQCGPCPEGFTGNGVTCSDTDECRNPCFPGVQCVNSVPGFKCEPCPPGYTGQVQGVGINYAKNNKQVCSDIDECNNNELCVPNSHCINTLGSYRCGPCKTGYVGDQIKGCNAEKSCRNRALNPCSIYAQCIEDVSCVCGIGWAGDGYICGKDVDIDGYPNEDLTCSADTCRKDNCRFVPNSGQEDADGDGIGDACDDDADGDGIPNEQDNCVLIPNVNQKNSDIFGDACDNCRTVPNNDQKDTDGDGKGDACDDDMDGDGIKNLLDNCQRIPNQDQKDKDNDGVGDACDSCPHISNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGLGDECDDDDDNDGIPDLIPPGPDNCRLVPNPGQEDENTDGVGDICESDFDQDTVIDQIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQAAPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWFLQHRPQMGYIRARFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFEEFQAQQFGVGDI >XP_014449911.1 PREDICTED: thrombospondin-4 [Alligator mississippiensis] M-SPRQLLLQLWGAQPGPQVFDLLSQRLVRNFLQPTLNEVYLLSTFKLQPKSTATIFGLYSSLENSKYFEFTVIGRLNRAALRYLRSDGRLNSVIFSNIDGKRHAVLLRLSGLHRGKVEMYVDCMQVDVDLPKAFSGLSSPEFVELRTLQRKAQDILDELKLVVRGSLSQDCFLQQIEP-EFNRQLMSQMQMNQILGDVKDLLRQQVKETTFLRNTIAECQACPMDF---------PTSPPPLKPRCEATSCFRGVRCTETADGFQCGPCPEGFTGNGVTCSDTDECRNPCFPGVQCVNSVPGFRCEPCPPGYTGQVQGVGINYAKNNKQVCSDIDECNNNELCVPNSHCINTLGSYRCGPCKTGYMGDQIKGCNAEKSCRNQALNPCSIYAQCIEDVSCVCGIGWAGDGYICGKDVDIDGYPNEDLTCSADTCRKDNCRFVPNSGQEDADGDGIGDACDDDADGDGIPNEQDNCVLIPNVNQKNSDIFGDACDNCRTVPNNDQKDTDGDGKGDACDDDMDGDGIKNLLDNCQRIPNQDQKDKDNDGVGDACDSCPHISNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGLGDECDDDDDNDGIPDLIPPGPDNCRLVPNPGQEDENTDGVGDICESDFDQDTVIDQIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQAAPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWFLQHRPQMGYIRARFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFEEFQAQQFGVGDI >XP_020725677.1 thrombospondin-4 [Odocoileus virginianus texanus] MLAPRHLALQPWGAQATPQVFDLLPQRLNPSVLQPTLNELYVISTFKLQSKSSATIFGLYSSADHSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLDGRRHRLLLRLTNLHRGSVELFLDCTRVDSNLPRAFSGLASPEAVELRTFQRKAHDSLEELKLVVRGSLIQDCFLQQSEPLAFNRQFLGQMQLNQLLAEVKDLLRQQVKETSFLRNTIAECQACPLSFQSPTPNTLVPAVPAPAPRRCDSSPCFRGVRCTDTRDGFQCGPCPEGYTGNGVACSDVDECKHPCYPGVRCVNLAPGFRCDACPVGFTGPMQGIGINFAKTNKQVCTDIDECR-NGACVLNSICVNTLGSYRCGPCKPGYIGDQMRGCKMERNCRDPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNSDIFGDACDNCRNVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCQKVPNRDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDRNSDGVGDICEADFDQDQIIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDK >XP_040196487.1 thrombospondin-4 [Rana temporaria] M-PKRLVLLELYEAQANYQVLDLLSQRQVTNYLQPSMNEVYVLSTFKLQPKSTVTLFGLYSTKENSRYFEFTVMGRLNKASLRYLKSDGRLNSVIFNNIDGKQHSLLLHLSGLHRGAAELYLDCIQVDADLPRPLTGLNNTGSVQLKTLQKKGQDSMDELKLVMGGSLTQECFMQQSEP--VSRQLLGQIQLNQLLGELRDVMRQQVKETMFLRNTVSECQACPDY--------PLPTQPPPPKPRCAATSCFQGVRCIDTESGFQCGPCPEGYTGNGIICTDTDECRNPCFPGVRCINTIPGFRCESCPPGYTGPVQGVGTTYARQNKQICLDINECENNGGCVTNSICTNTMGSFRCGPCKSGFVGDQIKGCKAEKSCSIRGSNPCHAGAQCIEEVTCICSVGWAGNGYFCARDTDIDGYPDEALLCSDPSCKKDNCIYVPNSGQEDTDKDGIGNSCDDDADGDGIMNEQDNCVLVANINQKNSDIFGDACDNCRFKLNNDQRDTDNDGEGDACDDDMDGDGIKNFLDNCQRVPNVDQKDKDGDGVGDACDSCPDIVNPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGLGDECDDDDDNDGIPDLIPPGPDNCRLVPNPGQEDDNNDGVGDICESDFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWIVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAIKSKTGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWFLQHRPQDGYIRARFFEGSELVADSGVTVDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQAFQAQQFTS--- >XP_043326699.1 thrombospondin-4 [Cervus canadensis] MLAPRHLALQPWGAQATPQVFDLLPQRLNPSVLQPTLNELYVISTFKLQSKSSATIFGLYSSADHSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLDGRRHRLLLRLTNLHRGSVELFLDCTRVDSNLPRAFSGLASPEAVELRTFQRKAHDSLEELKLVVRGSLIQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLSFQSPTPNTLVPVVPAPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGNGIACSDVDECKHPCYPGVRCVNLAPGFRCDACPVGFTGPMQGVGINFAKTNKQVCTDIDECR-NGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKMERNCRDPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNSDIFGDACDNCRNVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCQKVPNRDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDRNSDGVGDICEADFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDK >KAB0343956.1 hypothetical protein FD754_020882 [Muntiacus muntjak] MLAPRHLALQPWGAQATPQVFDLLPQRLNPSVLQPTLNELYVISTFKLQSKSSATIFGLYSSADHSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLDGRRHRLLLRLTNLHRGSVELFLDCTRVDSNLPRAFSGLASPEAVELRTFQRKAHDSLEELKLVVRGSLIQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLSFQSPTPNTLVPVAPAPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGNGIACSDVDECKHPCYPGVRCVNLAPGFRCDACPVGFTGPMQGVGINFAKTNKQVCTDIDECR-NGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKMERNCRDPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNSDIFGDACDNCRNVVNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCQKVPNHDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDRNSDGVGDICEADFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDK >KAB0375369.1 hypothetical protein FD755_013861 [Muntiacus reevesi] MLAPRHLALQPWGAQATPQVFDLLPQRLNPSVLQPTLNELYVISTFKLQSKSSATIFGLYSSADHSKYFEFTVMGRLNKAVLRYLKNDGRIHLVVFNNLDGRRHRLLLRLTNLHRGSVELFLDCTRVDSNLPRAFSGLASPEAVELRTFQRKAHDSLEELKLVVRGSLIQDCFLQQSEPLAFNRQFLGQMQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACPLSFQSPTPNTLVPVPPAPPVRRCDSNPCFRGVRCTDTRDGFQCGPCPEGYTGNGIACSDVDECKHPCYPGVRCVNLAPGFRCDACPVGFMGPMQGVGINFAKTNKQVCTDIDECR-NGACVLNSICINTLGSYRCGPCKPGYIGDQMRGCKMERNCRDPELNPCSVNAQCIEDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNSDIFGDACDNCRNVVNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCQKVPNHDQEDRDGDGVGDACDSCPEVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDRNSDGVGDICEADFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRLDK >NP_001087096.1 thrombospondin 4 S homeolog precursor [Xenopus laevis] MPRGKMLLLHLYQAQPNYQVFDLLSQRQVTSFLQPSMNEVYVLSTFKLQPKSTVTLFGLYSTSDNSRLFEFTVIGRLNKASLRYLRSDGKLHIVFFNNIDGKQHTLLLHMSGLHRGFADLYLDCHPVAGDLPRPLSGISNTGSVLLRTLQKRGQDSMDELKLVMGGTLSQECFMQQSEP--VSRQLIGQILMTQLLGELRDVMRQQVKETMFLRNTISECQACPDD--------PLPTEAPPPKPQCDASSCFRGVRCINAETGFQCGPCPEGYTGNGVICTDVDECQNPCFPGVRCINTSPGFKCESCPPGYTGSIQGIGINFAKQNKQVCTDINECENNGGCTSNSLCINTMGSFRCGACKPGYVGDQIKGCKPEKSCRH-GQNPCHASAQCSEDITCTCSVGWAGNGYLCGKDTDIDGYPDEALPCPDKNCKKDNCKYVPNSGQEDTDKDKIGDACDEDADGDGILNEQDNCVLAVNIDQKNSDIFGDACDNCRLTLNNDQRDTDNDGKGDACDDDMDGDGIKNILDNCQRVPNVDQKDKDGDGVGDACDSCPDIINPNQSDIDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGIGDECDDDDDNDGIPDTVPPGPDNCRLVPNPGQEDDNNDGVGDVCEADFDQDTVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWIVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTLTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKSGPGEHLRNALWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWFLQHRPQVGYIRARFYEGTELVADSGVTVDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQAFQAQQFSS--- >XP_030290980.1 thrombospondin-4-B-like [Sparus aurata] MGVWTQLLLKLCHVEAQALVYDLLTPDCLPDLLQQGVNEAFILATFKLQPKTGTSVFGLYNPRDNSKYFEFTVMGKLNRAVLRYLRSDNRMSSVTFNNLDGQQHRLLFHLRGMQQQGVELHLDCRLVETDLPAAFQGLPGYGMVELKTMQARDQESLDELKLVVGDSFEQDCHFQQRDS--NTKQLSNQMELTKVINELKDVLIQQVKETSFLRNTISECQACGSE---------------PVKPKCVSGVCFRDDMCQETAEGVECGPCPDGYTGDGFNCDDVDECQNPCFPGVKCVNTAPGYRCDACPLGYSGLVEGVGVLFAQTNKQVCDDVDECKGNGGCTENSQCHNSVGSYHCGSCKSGFTGDQVKGCKPELSCGNSLTNPCDINAQCIPTITCQCGIGWAGNGYLCGKDTDIDGYPDEKLKCKDPNCKKDNCVYVPNSGQEDADRDGYGDTCDDDADGDGIPNEQDNCWLKPNVDQRNSDSHGDACDNCRAVENPDQRDTDGDGKGDACDDDMDGDGLKNFLDNCQRVQNRDQLDRDGDGVGDACDSCPDIPNPNQSDIDNDLVGDSCDTNQDSDGDGHQDTKDNCPLVINSSQLDTDKDGLGDECDDDDDNDGIPDTLPPGPDNCRLVPNPDQIDDNNDGVGDVCESDFDQDKVIDRIDNCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSQSGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYLQHRPQVGYIRARFYEGTELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFSTQHGVDSL- >XP_015798465.1 PREDICTED: thrombospondin-4-B isoform X1 [Nothobranchius furzeri] MLVWTQLL----NVEAQALVYDLLTPDCLPDLLQQGVNDAFILTSFKLLPKTGTTVFSLYNPRDNSKYFEFTVMGKLNRAVLRYLRSDKRMSSITFNNLDGQQHRLLFHLKGLQQQGVELHLDCRLVETDLPAAFRGLPGYGLVELKTMQARAQESLDELKLVVGDSFEQDCHFQQRDS--NTKQLSNQMELTKVINELKDVLIQQVKETSFLRNTISECQACGTE---------------VVKPSCGPGVCFRDDMCIETADGVECAPCPDGYTGDGFNCDDVDECQNPCFPGVKCVNTAPGFRCDACPLGYIGLVEGVGIVFAQTNKQVCDDVDECKGNGGCTQNSHCHNSVGSFYCGSCKTGFTGDQVKGCEPELSCGNSLTNPCDVNAQCVRSISCQCGIGWAGNGYMCGKDTDIDGYPDEKLKCKDPNCKKDNCIYVPNSGQEDVDRDGLGDTCDDDADGDGIPNEQDNCWLKPNVDQRNSDSHGDACDNCRLVENPDQRDTDEDGKGDACDDDMDGDGLANFLDNCQRVQNRDQLDRDGDGVGDACDSCPDIPNPNQSDVDNDLVGDSCDTNQDSDGDGHQDTKDNCPFVINSSQLDSDKDGLGDECDDDDDNDGIPDLLPPGPDNCRLVPNPEQVDDNNDGVGDICESDFDQDKVIDRIDNCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKSGPGEHLRNSLWHTGDTNDQVRLLWKDPRNVGWKDKVSYRWYLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFSAQHAVDSI- >XP_004074610.1 thrombospondin-4-B [Oryzias latipes] MDMWRQLLLNLCHVEAQALVYDLLTPDCLPDLLQQGVNEAFILTSFKLQPKSGTTVFSLYNPRDNSKYFEFTVMGKLNRAVLRYLRSDRRMSSVTINNLDGQKHRLLFHLRGLQQQGLELHLDCRLVETDLPAAFQGLPGYGTVQLKTMQPREQESLDELKLAVGDSFEQDCHFQQRDS--NTKQLSNQMELTKVINELKDVLIQQVKETSFLRNTISECQACGSE---------------VVKPKCSPGVCFRDDMCIETANGVECAACPDGYTGDGFNCDDVDECQNPCYPGVKCVNTAPGFRCDACPLGYIGLVEGVGIVFAQTNKQVCDDIDECKGNGGCPANSNCENSMGSYHC-SCKTGFIGDPVKGCKPEVSCGNSLTNPCHANASCVLSISCQCGIGWAGNGYLCGKDTDIDGYPDEKLKCKDAHCRKDNCIYVPNSGQEDADRDGQGDACDEDADGDSIPNELDNCWLKPNVDQKNSDSHGDACDNCRLAKNPDQRDTDGDGKGDACDDDMDGDGLKNFLDNCQRVQNRDQLDRDGDGVGDACDSCPDIPNPNQSDIDSDLVGDSCDTNQDSDGDGHQDTKDNCPYVINSSQVDSDKDGLGDECDDDDDNDGIPDVLPPGPDNCRLVPNPDQMDDNDDGVGDVCESDFDQDKVIDRIDICPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFSGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTNHQVRLLWKDPRNVGWKDKVSYRWYLQHRPQVGYIRARFYEGTELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFRAQHAVDPI- >XP_043732019.1 thrombospondin-3 [Cervus elaphus] METQELALLLLCSASQDLQVIDLLTSRQMIAVVELTTGDIYLLSTFRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQADGRTHTALLRLRGPSKPALQLYVDCKLGDQGLPALAPIPPEVSGLEIRTGQKRMQGFVESMKMILGGSMASECPFQGDESIHQTKALVTQLLFNQILVELRDDIRDQVKEMSLIRNTIMECQVC------------------EQRSHCSPNPCFRGVDCMEVYEGYRCGPCPPGLQGNGTHCTDINECADPCFPGSSCINTMPGFHCEACPRGYKGTVSGVGIDYARASKQVCNDVDECNDNGGCDPNSVCTNTVGSFKCGPCRLGFVGNQSQGCSPARTCHSPAHSPCHVHAHCLFAVSCSCNVGWAGNGNVCGPDTDIDGYPDQALPCMDKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGVPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGNTPDQVRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVPEDFEPFRRQLLQGRV- >XP_039274396.1 cartilage oligomeric matrix protein-like [Styela clava] MDFYSSFIVGIEKSSMFMSEVDLLREKSAIRVTETKAHTISLAFELKVPPEEFVSVFAIYEKTGPRKYFEITVNGRQDKVSIKSRDDDDELHVTSFRKVNGQWHTMLIHFVITDSGETHFILDCAEKGRQIRKSRNSTLTKSTIDIKTHMRKAVLLHDEQLPIVRRNYGADMGIGSDPTLLPVSELIIQIDLASVLRDIHAGMKAQAIETKELRRTLQQCSACPTQSVSPTQGRFQVTEPPPVIRKCSSNPCDSQVECEDTEDGFTCGRCPSGFTGNGIHCDDIDECEDPCSAIAGCINTQGGYYCNLCPEGGFEQYKEIEVAERIIQKQVCTDIDECKVNGGCAEFSKCINTAGSYKCGACIPGYHGNQTSGCVKVRQCSDGALNPCDVNAECLVEYACECNAGYSGNGYVCGLDGDLDGYPNEQMPCNVKNCRQDNCPEVPNSGQEDSDLDGLGDACDSDADDDGISNDEDNCVLVPNKDQQNSDLFGDACDNCPNANNPQQLDHDDNGKGDECDTDIDGDGIGETLENCPFVPNVSQDDMDGDSVGDACDNCPTMSNPMQSDSDHDSIGDVCDTNTDSDGDGRQDNMDNCPHVLNCAQLDTDNDGKGDACDEDDDNDGIPDY-GKQTDNCRLINNPNQLDDDGDNIGDACENDQDGDGVVDWKDVCPYNRDISVTDFRSYQKVMLDPD-ESEVEPSWIVANEGMEITQKTNSDPGLLVGLDSFDGVDFSGTFFVNTASDDDYAGFLFSYQSSRKFYVVMWKQTSQEFWDDEPFRALALSGLHIKAVDSATGPGPDLRNALWHSGDTPNQVRTIWSDPNNVGWKDKTAYRWELKHRPETGYIRLKFYEVNKLVADTGAIIDNTVKGGRLGVFCFSQERIIWSHLKYKCNEAYPEDY------------- >XP_030832707.1 cartilage oligomeric matrix protein isoform X1 [Strongylocentrotus purpuratus] MQFGTMLSVTSSGVSPAPQFFNGISIIANQEFFKRKNEDVYFVIRSRLAPRHHGVLFGVYSSNYYSQRFELSYNGNGGKLVLKYR-VGDQQRQAEFPNLDGDWHTIILQFH-TERSTLTLYVDCRLANQKLSRVFSRTV--DGSEMRLGQAPLKGTIQNVRFMYGGPIGLSCSLSTEPKPLGATILMDAFSLSSTLMVLKNGMDDQTREIRHLRNTLENCRMC------------------IITHGCSSNPCFPDVMCFDEPDGYRCGPCPAGYRGNGSYCYDINECIYPCSDVVECINLVPGFRCPPCPEGFIGLLEGIGLEAAVRNRQVCDDINECERNGDCVPNSYCINTRGSHICGDCKHGFEGNQTVGCKQKNTCPNGERSPCHPKAKCIIAYTCECIIGWAGDGYDCALDTDLDGYPDYALPCTDKHCRADNCVYIPNSGQENQDGDEMGDICDPDADNDGVPNGPDNCPLVANPDQVNSDPVGERCDNCPMTPNPKQIDTDADGKGDECDDDKDNDGILNIYDNCELVPNRMQDDTDGDGLGDACDNCPMQYNPDQNNTDSDLLGDICDNNEDSDDDGIQDNLDNCPKIPNNPQLDSDGDGRGDACDDDDDSDGVYDI----VDNCRIIHNPDQADYNQDGIGDMCDSDFDRDGVDDQYDACPENPNIFTTDLRTYQTVVLDPEGEAQVDPKWIVFDEGRQIMQTINSDPGLAISYQAFDGVDFEGTFFVNTRTDDDFAGFVFGYQDSASFYVLMWKQGPQTYWEASPFRAVGEPGFQLKVIKSDTGPGEMMRNALWHTGDTPGQSRLLWKDPNNHGWKDHVAYRWRVVHRPSIGLIRVKLYEADSLVADSGFLRDTTMRGGRIGLFCFSQEDIIWARITYKCNDDIPEGV------------- >CAE1249094.1 THBS2S [Sepia pharaonis] -------------------MIALIAAQFRPLRKPMRYNELSLVGEIQLQSRGRATLLRAENLAMNTK-FDSYIDFQRAEVVINLKTKDGREYAVRFLTGENKNKKIIIRFTNLQSNGIQLFVNCMNAGRPIRDVLMG--NFSVQRHPAFKLYGQASLKELLMMQGCEDTQDPFYTVDQIKTVKPELPNAIELTIAIRDLQRDFQNQIRETHLLKETLKECQMCGVRCIDTEEGFRCGSCPPPTRVTCDSSPCFPGVMCTDQRTGFHCGSCPTGYTGNGTYCEDLDECQRPCDRRATCTNLSPGFTCTPCPQGYTSSITGIGILSAQQTRQICQDIDECRSNGGCVPHSRCINTRGSFRCSECDPGYSGNQTVGCRRQISCSNG--KECHKNARCIQTHECQCSIGYGGDGYYCSKDQDLDGIPDNALPCGHRKCRKDNCVSTPNSGQEDADGDGLGDACDPDADNDGIVNNPDNCPLVANPDQDDTDRKGDACDNCPTIPNPEQTDTDDDGMGDTCDPDADNDGIINAHDNCIRVKNADQRDTDGDGIGDACDNCPFVPNVKQLDSDADLTGDACDTNDDKDDDGVQDTNDNCPHIANSDQLDTDGDTLGDICDNDDDNDGVLDV----NDNCPLRMNPRQEDEDGNGVGDICEIDKDGDGSEDFIDVCPHNGNIYATDFRAYQTVILDPEGDSQIDPNWVILNQGAEIVQTMNSDPGIAISYTAFAGVDFSGTFYVNTEVDDDYAGFIFSYQDSSHFYVVMWKKNTQTYWHSTPFRAVAEPGIQLKLVNSSTGPGQYLRNALWHTGDTHDQVRLLWKDPRNEGWKERKAYRWELIHRPYKGLIRILFFEETELIADSGNIYDFTLKGGRLGVFCFSQEMVIWSDLVYRCNDYIPPGLLEEEDYGYGQ--- >XP_031556620.1 cartilage oligomeric matrix protein-like [Actinia tenebrosa] MKKSGSLLVLLSNTEAKIQDFDLIKLHLGPEFVSRESKSLTITSNLKLDRKSYGTLLSIETEGEGNLVFSLLFSCSSCRISLYYP-EGSLTSVTYFDKVDGKWHKMVLHIQTNRMGVVSLFMDCRSLGKGLDQLFPLSNEKVKYALRFAQRPWKGSLQSVLLIFGVRSHVDCLTKSTRQILLKKEQFHREALRKTIEMLRIDLNSQSQEVRYVRSFLEHGGACGRKT--------------VAGGKCLQKPCFPFVECYETPDGFRCGPCPPGFTGNGIRCEDVNECNYPCSALTKCINLRPGYQCTPCPVGYLGNSMGLGVEMARKNKQVCEDINECANNGGCSIHSECINTQGSYRCGPCKPGYDGDSTRECKRVLFCSNAPANPCGKLAHCIPNYECKCKPGYGGDGVRCGKDSDMDGYPDRALGCKGPKCAKDNCREIPNSGQEDVDGDGTGDACEYDADGDKPSKDQDNCPSVPNEDQQDTDGVGDACDNCQTVNNPDQEDTDKDGIGDACDVDIDGDGIINVLDNCPKVPNRDQKNTDGDPHGDACDNCKRGKNPDQADKDGDGIGDVCDFDQDYDRDGVDDRHDNCLRKPNAAQLDTDGDGLGDVCDSDDDNDGIPDY----KDNCRLVRNVDQKDSDNDGIGDACQGDYDNDGVPDAVDICPYNHNITKTDFSSFFNVNFDPLSKIKDYPQWKASKKGNEVYLRKNSNVGLFVATPKYEDIEFRGTMFVNTHQDDDIIGFAFGYQQYGHFFLLSWKRKEQMYWIVNPFRATAKTWLTLKRVKSSSVPSHGIRNALWHTAETRRHTKVLWQKRLTRGWKPKTAYRWELNYTPSNGYLRLQMWVGTQQLMDTGILRDLEMRGGRLGFFSFSQGDIIWSDLQVRCVDGK----------------- >XP_397221.5 cartilage oligomeric matrix protein isoform X1 [Apis mellifera] MRV--IITLIIT-------IFFLVYSITRDEDLEWNDDFVIVFSNIKSKKKQFQVMVEVLLTIKYEKKMVLMLDRRAKRVILENIDGHRVAQYINMDNLNFPSKNVIFLVHQSQPGRMAVYIDCIYRGVTFRELTNSE---DNLLIEAFREPLARSMEALQEENCLSTLVDLFEDTDQIDLTDNQIVKTLELIGATKKIWREIELNRLETHRVLLLIENCAACGSECRDTPRGPQCGACPPELKNVCEPNPCYSEVQCDLISEFYRCGVCPNGFTGNGSVCVDINECEQPCSLGVQCINLHPGFRCDPCPPGYTGTIEGVGLEIAMNRKQICQDINECENNGGCDPYMECINMQGSYRCGACRAGFIGNQTVGCHPAHSICPDLITRCDVNAECVCVYSCRCRVGWTGDGLICGIDRDNDGIPDRNLHCRDRHCRMDNCPLTPNSGQEDADRDGIGDACDPDADDDGVLNSSDNCPFISNPGQEDNDLVGDICDNCPRVRNPKQEDTDDDGIGDACDPDIDNDGIPNNQDNCQKIKNQNQNDMDEDGIGDACDNCPYGYNPNQLDQDGDGVGDDCDNDNDRDRDGVQDDRDNCPDVANSGQNDDDHDGIGNECDNDMDNDGVPNS----NDNCPYVYNPDQRHTHNNFIGDACWHDYDNDTVKNIHDNCPNNSLIWATDFRKYTTIALDPFGTAQEDPVWVIHNDGAEIQQLVNSDPGIAIGPDIFSGVDFEGTFFVDDDGDDDFVGFVFSYQDNRRFYIVAWKKAHQPYWVPTPFRAVGDPGIYLKLVDSDTGPGEILRNSLWHNENTINQVKILWHDPKKIGWKERTSYRWQLLHRPKIGLIRFRLYQGKQLMADSGNVYDSTLKGGKLGVYCFSQEKITWSNLLYVCKETVPLSVWNDLPSNLRKEIN >NP_001137802.1 thrombospondin, isoform F [Drosophila melanogaster] MNWTRVLLIGLT-------ALTFVDLSLDPVASARKGDVVISTRHIRPRRKLHISIEALFMIDFPMLKMSFFLDRKQQRVTLDIS-ANGATESRNFEIP----ETSTIRSLALQFSRITLHVDCKASTHNLAKLYTQM---DDPVIKLFREHFDGDMEHSLQRANCQKGQEVPTDVERGDICEDALARSLDLLALVKLLREDVAHQRQEIAYLRMLLENCAGCGVECLDSAAGPRCGHCPLSLRNPCLDTPCPSGAQCLQVGYYFHCISCPMGHEVNGTSCRDMNECLDPCDELATCTNLSPGFQCSPCPVGFDGTAHGYFADYVDYRRQTCLDVDECRTFFRCPEHSTCINEIGSYRC-QCHEGYVTNGTYSCLDRSSCPDG--TVCDRNAVCLRRHKCHCNVGWAGNGLICGRDTDVDGWPDQAIGCPELRCQRDNCPKLPNSGQEDADLDGHGDGCDDDADGDNVQNSQDNCWLAYNTEQLDSDKVGDVCDNCVLKYNPRQLDTDEDGLGDECDGDIDNDSIPNALDNCPLLPNPSQSDVDNDGVGDACDNCPNLPNPDQKDRDMDFVGDACHRDIDGDDDGVPNSLDNCPMVSNSDQLDTDGDGTGDECDDDMDGDGIPNY----KDNCPLAKNPKQDDFNRNGKGDSCEDDEDVDGVPNGMDNCPNNSMIHHTDFRTLQTIPLDPKGLSQADPNWVVHANGTEIVQTLNSDPGLAVGKDAFGGVDFDGTFYINDDTDDDYAGFVFSYQSSYKYYVVQWKKGTQTYWEPRPFTASAAPGIQIKLVNSTEGPGPMMRNSLWHEGNTDGEARLLWKDPKNIAWKERTSYRWSLVHRPAIGLIRLQMHEGNRLIFDSGNVFDSTLKGGRLGVFCFSQRMIIWSNLQYKCNNRVKPLIYNDLSDYLKTKVE >XP_038078580.1 thrombospondin-1-like isoform X1 [Patiria miniata] MPTRAALHCQLTGVRETKTAFKVRPLGTDQGSLEKADEGFILITVAYQDPKNRGTLVSVDRTDGQVRGFGFHIDRRNDEAVVQFAEGEPQESQVVFSPLDTELHTFVLDVR-----LVTLYMDCQLIG-LPSSFYMNM-EPDNMKLRLGKGDFKGTLAVAKFAFQTSTTSDAAMPGGEGNVQCAYTCEQINLNNQVQVLSDGYDDMWNKLEHFENKVDKCKSCEGDC--------CPTCPNCPIDACLSSPCFDGVECVSFTDRYECKDCPVGYTGNGILCQDINECLDACFNEHRCLNLIPGYTCRKCPIGYRGNPSGMGVYHAKRYKQQCIPINPCAE-------------------------------------------GTSSCHIDARCIFQYGCKCKTGFAGDGVHCGYDSDLDGWPDEQLDCEDTHCTRDNCASLPNSGQEDNDGDGKGDACDADDDDDLVDDVADNCQFISNWQQFDIDGVGDVCDNCPFVSNTRQEDTDSDGDGDVCDYDIDEDGIYNEDDNCMYVANARQLDFDEDGYGDVCDNCPDYGNPDQMDIDDDNVGDVCDTDRDVDNDGHQDDLDNCWNIANSDQADHDMDGIGDACDFDDDNDGIEDV----DDNCRLIFNPSQNDTNENGRGDACEYDNDGDGVTDLQDACPDNANIQRTDLSHFQLIKLDPEGSAQIDPHWIVRNRGQELVQTINSDPGLAIGYDEFNSVEFSGTFYVNTERDDDYAGFVFGYQSNHRFYSVMWKQVTQKYWEPMPTMSEATAGLQLKLINSTTGPGEYLRNALWHTGDTSDQVKLIWSDANKIGWKDFTAYRWILTHRPRTGYIRVTMYEGSKVLADSGALYDFTLQGGRIGLFCFSQEMVFFSDLQYKCLAEE-----------------
PhyML tree of selected proteins (CAE1249094_1_THBS2S__Sepia_pharaonis_:0.82636885,(XP_397221_5_cartilage_oligomeric_matrix_protein_isoform_X1__Apis_mellifera_:1.12463339,NP_001137802_1_thrombospondin__isoform_F__Drosophila_melanogaster_:1.14042733):0.35970917,(XP_038078580_1_thrombospondin_1_like_isoform_X1__Patiria_miniata_:1.61194108,(XP_030832707_1_cartilage_oligomeric_matrix_protein_isoform_X1__Strongylocentrotus_purpuratus_:0.89554854,(XP_031556620_1_cartilage_oligomeric_matrix_protein_like__Actinia_tenebrosa_:1.73707918,(XP_039274396_1_cartilage_oligomeric_matrix_protein_like__Styela_clava_:1.2079386,(XP_043732019_1_thrombospondin_3__Cervus_elaphus_:0.44446134,(((XP_040196487_1_thrombospondin_4__Rana_temporaria_:0.07843437,NP_001087096_1_thrombospondin_4_S_homeolog_precursor__Xenopus_laevis_:0.08647466):0.10277812,(((XP_021147870_1_LOW_QUALITY_PROTEIN__thrombospondin_4__Columba_livia_:0.02715022,(XP_019465735_1_thrombospondin_4__Meleagris_gallopavo_:0.03983546,NP_001308478_1_thrombospondin_4_precursor__Gallus_gallus_:0.01677896):0.04760731):0.08068277,(XP_014449911_1_PREDICTED__thrombospondin_4__Alligator_mississippiensis_:0.00402279,XP_025057186_1_thrombospondin_4__Alligator_sinensis_:0.01290003):0.06494022):0.05387351,(XP_008260094_1_PREDICTED__thrombospondin_4__Oryctolagus_cuniculus_:0.08531822,((((XP_020940149_1_LOW_QUALITY_PROTEIN__thrombospondin_4__Sus_scrofa_:0.0157062,((NP_001029900_1_thrombospondin_4_precursor__Bos_taurus_:0.00679183,(XP_017909157_1_PREDICTED__thrombospondin_4__Capra_hircus_:0.00115412,XP_027827293_1_thrombospondin_4__Ovis_aries_:0.00000001):0.00661536):0.00161288,((KAB0375369_1_hypothetical_protein_FD755_013861__Muntiacus_reevesi_:0.00230398,KAB0343956_1_hypothetical_protein_FD754_020882__Muntiacus_muntjak_:0.00000001):0.00346952,(XP_020725677_1_thrombospondin_4__Odocoileus_virginianus_texanus_:0.01045501,XP_043326699_1_thrombospondin_4__Cervus_canadensis_:0.00000001):0.00000001):0.00121656):0.02472299):0.01266315,(NP_058829_1_thrombospondin_4_precursor__Rattus_norvegicus_:0.01264078,NP_035712_1_thrombospondin_4_precursor__Mus_musculus_:0.01778567):0.02684401):0.00443558,(XP_003981157_1_thrombospondin_4__Felis_catus_:0.02190459,XP_038327488_1_thrombospondin_4__Canis_lupus_familiaris_:0.01995386):0.00739479):0.0075005,(XP_024103393_1_thrombospondin_4__Pongo_abelii_:0.00348295,(XP_004058683_1_thrombospondin_4__Gorilla_gorilla_gorilla_:0.00232857,(sp_P35443_TSP4_HUMAN_Thrombospondin_4_OS_Homo_sapiens_OX_9606_GN_THBS4_PE_1_SV_2:0.00116237,(XP_016808573_2_thrombospondin_4__Pan_troglodytes_:0.00000001,XP_008974044_2_thrombospondin_4_isoform_X1__Pan_paniscus_:0.00000001):0.00000001):0.00000001):0.00118428):0.04034397):0.01533571):0.1162552):0.04865978):0.06299544,(tr_F1R1P9_F1R1P9_DANRE_Thrombospondin_4_B_OS_Danio_rerio_OX_7955_GN_thbs4b_PE_3_SV_1:0.10935369,(XP_030290980_1_thrombospondin_4_B_like__Sparus_aurata_:0.02840944,(XP_015798465_1_PREDICTED__thrombospondin_4_B_isoform_X1__Nothobranchius_furzeri_:0.03449192,XP_004074610_1_thrombospondin_4_B__Oryzias_latipes_:0.06714289):0.02085553):0.06266299):0.2214317):0.23787488):0.20465131):0.15903682):0.07731307):0.16277793):0.16575974);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)