PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0125 | Q02818 | Nucleobindin-1 | NUCB1 | CALNUC, NUC | Homo_sapiens | Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins) (By similarity). |
Domains | Gene Ontology |
PF13499 (EF-hand_7) |
GO:0001965 (enables) G-protein alpha-subunit binding
GO:0003677 (enables) DNA binding GO:0005085 (enables) guanyl-nucleotide exchange factor activity GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0046872 (enables) metal ion binding GO:0007264 (involved in) small GTPase mediated signal transduction GO:0050790 (involved in) regulation of catalytic activity GO:0005793 (is active in) endoplasmic reticulum-Golgi intermediate compartment GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005737 (located in) cytoplasm GO:0005788 (located in) endoplasmic reticulum lumen GO:0005794 (located in) Golgi apparatus GO:0016020 (located in) membrane GO:0070062 (located in) extracellular exosome |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |