PB0124
DATABASE


Click here to access PB0124 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0124 P00742 Coagulation factor X F10 FX, FXA Homo_sapiens Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.

DomainsGene Ontology
PF00008 (EGF)
PF00089 (Trypsin)
PF00594 (Gla)
GO:0004252 (enables) serine-type endopeptidase activity
GO:0005509 (enables) calcium ion binding
GO:0005515 (enables) protein binding
GO:0005543 (enables) phospholipid binding
GO:0008233 (enables) peptidase activity
GO:0008236 (enables) serine-type peptidase activity
GO:0016787 (enables) hydrolase activity
GO:0006508 (involved in) proteolysis
GO:0007596 (involved in) blood coagulation
GO:0007599 (involved in) hemostasis
GO:0030335 (involved in) positive regulation of cell migration
GO:0051897 (involved in) positive regulation of protein kinase B signaling
GO:0005615 (is active in) extracellular space
GO:0005576 (located in) extracellular region
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0005796 (located in) Golgi lumen
GO:0005886 (located in) plasma membrane
GO:0031233 (located in) intrinsic component of external side of plasma membrane

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences


Created by Puigbo and Nakamura @ University of Turku (2022)