PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0121 | O75443 | Alpha-tectorin | TECTA | DFNA12, DFNA8, DFNB21, tectorin alpha | Homo_sapiens | The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. |
Domains | Gene Ontology |
PF00094 (4_VWD) PF00100 (Zona_pellucida) PF01826 (3_TIL) PF06119 (NIDO) PF08742 (4_C8) PF12714 (2_TILa) |
GO:0005201 (enables) extracellular matrix structural constituent
GO:0007160 (involved in) cell-matrix adhesion GO:0007605 (involved in) sensory perception of sound GO:0005576 (located in) extracellular region GO:0005886 (located in) plasma membrane GO:0016020 (located in) membrane GO:0031012 (located in) extracellular matrix GO:0031225 (located in) anchored component of membrane GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |