PB0094

DATABASE

Click here to access PB0094 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0094	Q8IUL8	Cartilage intermediate layer protein 2	CILP2	CLIP-2	Homo_sapiens	May play a role in cartilage scaffolding.

Domains	Gene Ontology
PF00090 (TSP_1) PF13330 (Mucin2_WxxW)	GO:0005615 (is active in) extracellular space GO:0005576 (located in) extracellular region GO:0070062 (located in) extracellular exosome

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|Q8IUL8|CILP2_HUMAN Cartilage intermediate layer protein 2 OS=Homo sapiens OX=9606 GN=CILP2 PE=2 SV=2 MASLLPLLCLCVVAAHLAGARDATPTEEPMATALGLERRSVYTGQPSPALEDWEEASEWT SWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHLNPTRG FWCLNREQPRGRRCSNYHVRFRCPLEASWGAWGPWGPCSGSCGPGRRLRRRHCPSPAGDA CPGRPLEAQKCVRPRCPGCSLDTCECPDHILLGSVVTPSGQPLLGARVSLRDQPGTVATS DAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQANGSISVVTIILDKLEKPYLVKHPES RVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRAHGYGAHLELRGLRPDQAGIYHCK AWNEAGAVRSGTARLTVLAPGQPACDPRPREYLIKLPEDCGQPGSGPAYLDVGLCPDTRC PSLAGSSPRCGDASSRCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVV AADSGEPLRFARILLGQEPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPF DPRGAGVYHEVKAMRKKAPVILHTSQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYS GPVEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGP VAVRVAASQIHMPGHVEALKLWSLNPETGLWEEESGFRREGSSGPRVRREERVFLVGNVE IRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGR FDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSLPRPLPATVGVTQPYLD RLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFA RVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGG SHPRTRGQLYGLRDARSVRDPERPGTSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRR VAVNGLLRDYLTRHPPPVPAEDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRC FDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMSEAAQAQ ARASGPLRTRRGRVRQ >tr|F1Q5N7|F1Q5N7_DANRE Cartilage intermediate layer protein 2 OS=Danio rerio OX=7955 GN=cilp2 PE=4 SV=3 MWDFTVVTLVLSTVFVVSLAQGPIWDSSRLRRLNQTDRNRKLAYNTLVEPQTTGVTEWTS WFNIDHPGGNGDYERLEAIRFYYRERVCSRPVAMEARTTDWVAAADTGEVVHSSLEKGFW CINKEQPFGRSCSNYHVRFQCPPVHSYWTDWSEWTPCSATACNDVGIQVRQRKCMSTQPL PLLLSPVCVGPHIERRECSTPPCQAMWSQWGSWGACSVTCGKGRRTRRRTCHRSSTKIQC TGRPIEVQKCGNPCPVKCKRVCPGGRPDKSCSYCICDGQALHGEVFSITGVPVMNATVAL ASQAKIIRAHTDAKGQFKMDGLCISPQTQIVIRKDKFAPATLPVSNNSTDELWVRAILQS SEKPYIEKHPEDKVRYEGQRATLCCRATGSPKPDKYYWYHNGTLLNRTIFKYDEDLILRD LKPEQSGQYHCKATSLTGSIKSTSAVLTVFTKGTPACKSTPETHLIKLPLDCKQPGTDSK FYNAGRCPHNKCPGALDFDMRCRDGTGFCCGVKEMDAKEINCGRYTLPIKVVSECGCQTC VEPKVLVRGRVVATDNDEPLRFGHIYIGKERIGTTGYQGGFTIQVSPETQRLVVNFVDPS QKFIDTIKVFIFDKRGGAVYHDVKVMRKQEPIDINAAESNTIYLGEMKDEDPIGQLVIPP NSFHKNTGEVYEGTVKASVTFLDPRNITMAAAAPGDLNFVDDEGDMLPLRTYGMFSVDFR DGENQEVLGAGAVQVLLDTEHVKMQEHIPAMKLWSLNPDTGIWEEESNFQPTQSTIAGTG RNKREERTFLIGNMEIRERRLFNLDVPENRRCYVKVRAYMSDKFLPNEQLEGVVINLINL EPKPGYSSNPRAWGRFDSVITGPNGACLPAFCDAQRADAYTAYVTAIMGGEELEAAPSMP KMNPNIIGVSQPYLGKLDYQRSDHEDSALKKTAFRINLAKPNPNNFDETNGPIYPFQSLI ACENAPVDANHFRFFRVEKDKYEYNVVPFQESDLTSWTGDYLSWWPNPQEFRACFIKVKI HGATEIMVRSRNLGGTHPQTRGQLYGIRDIRSTRDLHHPNTSAACLEFKCSGMLFDQGSV DRSLISVIPQANCRRIGINSLLQEYLIKHPPVLQNNESHAFNMLAPVDPLGHNYGIYTVT DQNPRVAKEIAIGRCFDGTSDGFSREMKSDSGVALTFSCPKRTVNRESLFQRLQTNPGLT LTQMAREMRESQGLQVRRGSTQMVAYPFGQQGRSQNRRATNTNRRRPASRTQPRQ
Selected proteins from model organisms >sp|Q8IUL8|CILP2_HUMAN Cartilage intermediate layer protein 2 OS=Homo sapiens OX=9606 GN=CILP2 PE=2 SV=2 MASLLPLLCLCVVAAHLAGARDATPTEEPMATALGLERRSVYTGQPSPALEDWEEASEWT SWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHLNPTRG FWCLNREQPRGRRCSNYHVRFRCPLEASWGAWGPWGPCSGSCGPGRRLRRRHCPSPAGDA CPGRPLEAQKCVRPRCPGCSLDTCECPDHILLGSVVTPSGQPLLGARVSLRDQPGTVATS DAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQANGSISVVTIILDKLEKPYLVKHPES RVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRAHGYGAHLELRGLRPDQAGIYHCK AWNEAGAVRSGTARLTVLAPGQPACDPRPREYLIKLPEDCGQPGSGPAYLDVGLCPDTRC PSLAGSSPRCGDASSRCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVV AADSGEPLRFARILLGQEPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPF DPRGAGVYHEVKAMRKKAPVILHTSQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYS GPVEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGP VAVRVAASQIHMPGHVEALKLWSLNPETGLWEEESGFRREGSSGPRVRREERVFLVGNVE IRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGR FDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSLPRPLPATVGVTQPYLD RLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFA RVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGG SHPRTRGQLYGLRDARSVRDPERPGTSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRR VAVNGLLRDYLTRHPPPVPAEDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRC FDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMSEAAQAQ ARASGPLRTRRGRVRQ >tr|F1Q5N7|F1Q5N7_DANRE Cartilage intermediate layer protein 2 OS=Danio rerio OX=7955 GN=cilp2 PE=4 SV=3 MWDFTVVTLVLSTVFVVSLAQGPIWDSSRLRRLNQTDRNRKLAYNTLVEPQTTGVTEWTS WFNIDHPGGNGDYERLEAIRFYYRERVCSRPVAMEARTTDWVAAADTGEVVHSSLEKGFW CINKEQPFGRSCSNYHVRFQCPPVHSYWTDWSEWTPCSATACNDVGIQVRQRKCMSTQPL PLLLSPVCVGPHIERRECSTPPCQAMWSQWGSWGACSVTCGKGRRTRRRTCHRSSTKIQC TGRPIEVQKCGNPCPVKCKRVCPGGRPDKSCSYCICDGQALHGEVFSITGVPVMNATVAL ASQAKIIRAHTDAKGQFKMDGLCISPQTQIVIRKDKFAPATLPVSNNSTDELWVRAILQS SEKPYIEKHPEDKVRYEGQRATLCCRATGSPKPDKYYWYHNGTLLNRTIFKYDEDLILRD LKPEQSGQYHCKATSLTGSIKSTSAVLTVFTKGTPACKSTPETHLIKLPLDCKQPGTDSK FYNAGRCPHNKCPGALDFDMRCRDGTGFCCGVKEMDAKEINCGRYTLPIKVVSECGCQTC VEPKVLVRGRVVATDNDEPLRFGHIYIGKERIGTTGYQGGFTIQVSPETQRLVVNFVDPS QKFIDTIKVFIFDKRGGAVYHDVKVMRKQEPIDINAAESNTIYLGEMKDEDPIGQLVIPP NSFHKNTGEVYEGTVKASVTFLDPRNITMAAAAPGDLNFVDDEGDMLPLRTYGMFSVDFR DGENQEVLGAGAVQVLLDTEHVKMQEHIPAMKLWSLNPDTGIWEEESNFQPTQSTIAGTG RNKREERTFLIGNMEIRERRLFNLDVPENRRCYVKVRAYMSDKFLPNEQLEGVVINLINL EPKPGYSSNPRAWGRFDSVITGPNGACLPAFCDAQRADAYTAYVTAIMGGEELEAAPSMP KMNPNIIGVSQPYLGKLDYQRSDHEDSALKKTAFRINLAKPNPNNFDETNGPIYPFQSLI ACENAPVDANHFRFFRVEKDKYEYNVVPFQESDLTSWTGDYLSWWPNPQEFRACFIKVKI HGATEIMVRSRNLGGTHPQTRGQLYGIRDIRSTRDLHHPNTSAACLEFKCSGMLFDQGSV DRSLISVIPQANCRRIGINSLLQEYLIKHPPVLQNNESHAFNMLAPVDPLGHNYGIYTVT DQNPRVAKEIAIGRCFDGTSDGFSREMKSDSGVALTFSCPKRTVNRESLFQRLQTNPGLT LTQMAREMRESQGLQVRRGSTQMVAYPFGQQGRSQNRRATNTNRRRPASRTQPRQ >NP_081094.2 cartilage intermediate layer protein 2 precursor [Mus musculus] MASPLPLLYLCLAALHLAGARDATPTEEHTSTARGLQGRPPDTGQPSPALEDWEEASEWTSWFNVDHPGG DGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPAAMGERVHANPERGFWCLNREQPRGRRCSNYHVR FRCPLEAAWGAWGAWGLCSKSCGLGRRLRRRSCQSSSGDTCPGSPQEAQKCVRSRCPGCSSDTCGCPNHI LLGSVVTPSGRPLSGARVSLRTRPGTIATSGTHGTFQVPGVCAGSKASVSAQMNGFSAGTAQAHANSSNT ATVTIILEELGKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRQQGSGPHLELQGL HQAQAGEYHCKAWNEAGTVRSRAALLTILAPGQQACDPRPQEHLIKLPDDCGQPGGGPTYLDVGLCADTR CPGPVGSGPRCGDAGSRCCSVLRLESRDIRCSGYVLPVKVVAECGCRKCLPRRGLVRGRVVAADSGEPLR FARILLGRAPIGFTSYQGDFTIEVPPATERLVVTFVDPSGDFVDSVRVLPFDPRGAGVYHEIRALRKAAA VLLDAERGGEIPLGSTEEAPALGELVLPPGTFHHPDGRPYTGPVEARVTFVDPRDLASASAASSDLRFLD SAGELAPLRTYGMFAVDLRAPGSTEQLHVARADVHVDADHVRMPGHAEALALWSLDPETGLWEEEGSEQG SGGFRRETAAARVRREERAFLVGALTMRERRLFNLDVPERRRCFVKVRAYGTDRFAPAEQVQGVVVTLLN LEPAPGFTANPRAWGRFDSAVTGPNGACVPAFCDAEKPDAYTAFVTAALGGEELEAAPSRPRATAAVVGV AQPYLERLGYQRTDHDDPALKRTGFRLNLARPRAGHESEAHGPVYPWRRLRDCEDAPVTDSHFRFSRVEA DKYEYDVVPFHEGAPASWTGDLLAWWPNPQEFRACFLKVRLQGPQEYMVRSHNAGGTHEATRGRLYGLRD TRSVRHPERPGASAACVEFKCGGMLFDQRQVDRTLVTVTPQGSCRRVAVNTLLQDYLARHPPLAAADDPA AFAMLAPLDALGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPARPSLF QRLLENPSSALGDIRREMGQATRYSRVNQTQAGDTGPFGPGQ >NP_001100777.1 cartilage intermediate layer protein 2 precursor [Rattus norvegicus] MSSPLPLLYLCIAAAHLAGARDATPTEEHTATVRGLQGRPPDPGQPSPALEDWEEASEWTSWFNVDHPGG DGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPAAIGERVHANPERGFWCLNREQPRGRRCSNYHVR FRCPLDPPYLPPCSAEAAWGAWGAWGLCSKSCGPGRRLRRRSCQSSSGDTCPGSPQEAQKCVRSRCPAPP KSSLCPCCSHVPLGCSSDTCGCPNHILLGSVVTPSGRPLSGARVSLRTRPGTVATSDTHGTFRVPGVCAG SKANVSARMNGFSTGTAQAHANTSNSAVVTIVLEELGKPYLVKHPESRVREAGQNVTFCCKASGTPMPKK YSWFHNGTLLDRRQQGSGPHLELQGLREEQAGEYHCKAWNEAGTVRSRAAHLTVLAPGQPACDPRPQEHL IKLPDDCGQPGGGPTYLDVGLCADTRCPGPVGSGPRCGDAGSRCCSVLRLESRDIRCSGYVLPVKVVAEC GCRKCLPRRGLVRGRVVAADSGEPLRFARILLGLAPIGFTSYQGDFTIEVPPATERLVVTFVDSSGEFVD SIRVLPFDPRGAGVYHEIRVLRKAAAVLLDAEQGGEIPLGGTEEAPALGELVFPPRTFHHPDGRPYSGPV EARVTFVDPRDLASAAAASSDLRYLDSSGELAPLRTYGMFAVDLHAPGSTEQLHVARADVRVDADHVRMP GHADALALWSLDPETGLWEEEGAEQGGGGFRREKEAVRVRREERTFLVGALTVRERRLFNLDVPERRRCF VKVRAYGTDRFAPSEQVQGVVVTLLNLEPAPGFTANPRAWGRFDSAVTGPNGACVPAFCDAERPDAYTAF VTASLGGEELEAAPSRPRATAATVGVAEPYLERLGYQRTDHDDPALKRTGFRLNLARPRTGHESEAHGPV YPWRRLRDCEDAPVTDSHFRFSRVEADKYEYDVVPFHEGAPASWTGDLLAWWPNPQEFRACFLKVRLQGP QEYMVRSHNAGGTHEDTRGHLYGLRDTRSVRNPERPGASAACVEFKCGGMLFDQRQVDRTLVTVTPQGSC RRVAVNTLLQDYLARHPPLAPADDPATFAMLAPLDALGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGF SREMKADAGTAVTFQCREPPARPSLFQRLLENPASALGDIRREMGQAARDSRVTQTQAGDTGPFGSGQ >XP_015155600.3 cartilage intermediate layer protein 2 [Gallus gallus] MERLLLPALLALAAFCCSGAAESLENDSEPGKSDAPGKPWKVPSPEELDLNTAGGGAEWTSWFNIDHPGG DGDYESLDAIRFYYRGRVCARPVAIQARTTEWELPQDVGEVVHFSPKKGFRCVNKEQPHGKTCSNYHIRF LCPLEHIFWSHWSSWSPCSRSACGSSGTQSRRRRCVNAQAVSALKELKCRGKAVERRPCSTGPCPEPMWT EWGAWGPCSRSCGSTGTRVRRRSCQNARKLLCAGHPSEVQQCPPTPCPACPEHTLQGAVVSATGAALPGA RVYLEGRPPTLLARSDTRGAFRVPGLCVSIGANVSAHRDGFAPGLTSVVSNGSGALVAHIVLQKLEKPYM VLHPTPKVRVAGQEVTFCCKASGTPVPKKYYWYQNGTLLDRTAHRYSSRLVLRALTPEQAGSYHCKASTE AGAIRSAPAQLTVLAQGQQSCKAAPEPSLVELPAECHRDAGASRYYDVGHCPSTPCAGSPADGQRCGAGA RRCCGVRRMEMREIRCGGSVLPIKVVAKCGCGPCAQPRVLVQGRVTAADTGEPLRFGQIFLGKKKIGFTG FQGSFTIEVPPDTQRLVARFVDRQQRLVDAVKVLPFDRRGGAVYQEVKMMRKKEAVELDAGQTNAIPLGE ASGREPIAELVIPAGAFLRPSGEVFGGTVKASVTFLDPRDMATARAASSDLSFANADGEIVPLRTYGMFA VDFRDGESGTALQTGPVEVRMDAGQIGMAEHLRKMKLWSLNPETGLWEEEGVLRPTEERRGRREERTFLV GNMEIRERRLFNLDVPEDRRCFVKVRAYSNEKFNPYEQLEGVVISLINLEPQPGFPANPRAWGRFDSVVT GPNGACLPAFCDARRPDAYTAYITATLGGEELEAVPSSPKLNPNAVGVSQPYLNKLGYRRLDHDDPDIKK TAFQVNVAKPDPNNIDETNGPIYPYRSLRECEEAPVSANHFRFYRVEVDKYEYNVVPFKESDLTSWTGDY LSWWPNPQEFRACFIKVRIEGPQEYMVRSRNEGGSHPRTVGQLYGLRDARSVRDAMREGSSGACLEFKCS GMLYDQSLVDRTLVSVIPQGSCRRTAVNGLLRDYLARHPPVADANNTAAFTMLAPVDPLGHNYGIYTVTD QNPRLAKEIAIGRCFDGTSDGFSREMKSDAGTAVTFTCQERPAGRESFFQRLLTSPAEALDEIRREMGAG ELRRAPPEVLDFASGVRALSPAPPPRTPGSRRRMGRVRAQQ >XP_541920.2 cartilage intermediate layer protein 2 isoform X1 [Canis lupus familiaris] MASAPPLLCLLVAAAHLAGARATTTPEEPTATAWGLEGPSLSPGQPSPALEDWEEASEWTSWFNVDHPGG DGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSTVGERVHLNPTRGFWCLNREQPRGRRCSNYHVR FRCPLEATWGAWGPWGPCSGSCGPGRRLRRRRCPSPTGDACPGRPLEAQKCVRPTCPGCSSKTCKCPNHV LLGSVVTPSGRPLPGARVSLRDWSGTVAITDAHGTFRMPGVCANSRANVSAQMDGFSAGLGQAQANGSIS AVVTVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPVPKKYSWFHNGTLLDRREHRYGAHLELRGL RPDQAGTYHCKAWNDAGTVRSGTAWLTVLGPGQPACNPQPQEHLIKLPDDCGQPGSGPTYLNVGLCPDTL CPSPAGSSPRCGDAGSRCCSVRRLESREIHCSNYVLPVKVVAECGCQKCLPPRGLVRGRVVATDSGEPLR FAQILLGQEPIGFTSYQGDFTIEVPPSTQRLVVTFLDPSGEFMDTVTVLPFDPRGGGVYHDVKAMRKKAP VILDAGESNRIPLGEMQDEAPLGELVLPPGAFRRADGEPYTGAVEARVTFVDPRDLSSAAAAPSDLRFVD SDGELAPLRTYGMFSVDLRAAGSAEQLQAGPVAVRVDAGQIRMAGHVEALRLWSLNPDTGLWEEESGFQP ERSAAARARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPNEQVEGVVVTLVNLEPAP GFSANPRAWGRFDSAVTGPNGACLPAFCDEARPDAYTALVTASLGGEELEPAPSRPRPRAATVGVAQPYL ERLAYRRTDHDDPALKRNGFRINLAKPRPGEPAEAKGPVYPWRSLRECQEAPVTASHFRFARVEADKYEY NVVPFREGAPASWTGDVLAWWPNPQEFRACFLKVQIQGPQEYMVRSHNAGGSHPRTQGQLYGLRDARSVR DPERPGTTAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAINGLLRDYLARHPPAAPADDPAAFSML APLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKAEAGTAVTFQCREPPAGRPSLFQRLL ESPATALGDIRREMGQVARAQAQSTGPLRTRRGRAQQ >NP_001179457.1 cartilage intermediate layer protein 2 precursor [Bos taurus] MSSLPTLLCLCVAAAHLAGARGTPDAEEPTVTAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGG DGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVR FRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCSSPAGDACPGRPSEAQKCVRPRCPGCGPSTCGCPDHI LLGSVVTPSGRPLPGARVSLRDWPGTIATSDAHGTFRMPGVCASSQANVSAQMDGFSAGMTQAQANSSMS SVATVVLNKLEKPYLVKHPESQVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELHGL RPDQAGTYHCKAWNDAGAVRSGAARLTVLAPGQPACDPRPREHLIKLPDDCGQPGRGPTYLDVGLCPDTL CPSPAGSSPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKVVAECGCQKCLPLRGLIRGRVVAADSREPLR FARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEVKAMRKKAP IILDARQSNTISLGEMGEEAPLGELIIPPGAFRRADGQPYTGAVEAQVTFVDPRNLTSAAAAPSDLLFVD GDGELAPLRTYGMFSVDLRAAGSAEQLQTGLVAVRVAADQIRMPGHMEALKLWSLNPDTGLWEEESGFQR ERPASQRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAP GFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATLGGEELEPAPSRPRPLPAAVGVAQPYL DRLDYRRTDHDDPALKRSGFRINLAKPRPGEPTEANGPVYPWRSLRECQEAPVTASHFRFARVEADKYEY NVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVR DPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPLAPTDDLASFSML APLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLL ESPSAALGDIRREMGESARVQARASSPLRTRRGRAQQ >XP_043323422.1 cartilage intermediate layer protein 2 isoform X1 [Cervus canadensis] MASLPTLLYLCVAAAHLAGARGTPDTEEPTVTAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAI RFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGSWGPWGPCSG SCGPGRRLRRRRCPSPAGDACPGRPSEAQKCVRPRCPGCGPNTCGCPDHILLGSVVTPSGRPLPGARVSLRDWPGTIATS DAHGTFRMPGICASSRANISAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTP MPKKYSWFHNGTLLDRRTHRYGAHLELHGLRPDQAGAYHCKAWNDAGAVRSGIARLTVLAPGQPACDPRPREHLIKLPDD CGQPGRGPTYLDVGLCPDTLCPSPAGSRPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRV VAADSREPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEIKAMRKKAP IILDASQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGVVEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRT YGMFSVDLRAAGSAEQLQTGLVAVRVATDQIRMPGHLEALKLWSLNPDTGLWEEESSFQRERPASQRARREERVFLVGNV EIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDA DQPDAYTAVVTATLGGEELEPAPSRPRPLPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVY PWRSLRECQEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLG GSHPRTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAP SDDLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLL ESPSAALGDIRREMGDVTRVQARASSPLRTRRGRAQQ >KAB0361517.1 hypothetical protein FD754_005673 [Muntiacus muntjak] MASLPTLLCLCVAAAHLAGARGTPDTEEPTVTAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAI RFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGSWGPWGPCSG SCGPGRRLRRRRCPSPARDACPGRPSEAQKCVRPRCPGCDPNTCGCPDHILLGSVVTPSGRPLPGARVSLRDWPGTIATS DAHGTFRMPGICASSRANVSAQMDGFSAGMAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTP MPKKYSWFHNGTLLNRRTHRYGAHLELHGLRPDQAGAYHCKAWNDAGAVRSGIARLTVLAPGQPACDPRPREHLIKLPDD CGQPGRGPTYLDVGLCPDTLCPSPAGSRPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRV VAADSREPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEIKAMRKKAP IILDSSQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGAVEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRT YGMFSVDLRAAGSAEQLQTGLVAVRVATDQIRMPGHLEALKLWSLNPDTGLWEEESGFQRERPSSQRARREERVFLVGNV EIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDA DQPDAYTAVVTATLGGEELEPAPSRPRPLPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVY PWRSLRECQEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLG GSHPRTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAP SDDLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLL ESPSAALGDIRREMGDVTRVQARASSPLRTRRGRAQQ >KAB0385514.1 hypothetical protein FD755_000470 [Muntiacus reevesi] MASLPTLLCLCVAAAHLAGARGTPDTEEPTVTAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAI RFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGSWGPWGPCSG SCGPGRRLRRRRCPSPARDACPGRPSEAQKCVRPRCPGCDPNTCGCPDHILLGSVVTPSGRPLPGARVSLRDWPGTIATS DAHGTFRMPGICASSRANVSAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTP MPKKYSWFHNGTLLDRRTHRYGAHLELHGLRPDQAGAYHCKAWNDAGAVRSGIARLTVLAPGQPACDPRPREHLIKLPDD CGQPGRGPTYLDVGLCPDTLCPSPAGSRPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRV VAADSREPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEIKAMRKKAP IILDSSQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGAVEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRT YGMFYVDLRAAGSTEQLQTGLVAVRVATDQIRMPGHLEALKLWSLNPDTGLWEEESSFQRERPTSQRARREERVFLVGNV EIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDA DQPDAYTAVVTATLGGEELEPAPSRPRPLPAAVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVY PWRSLRECQEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLG GSHPRTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAP SDDLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLL ESPSAALGDIRREMGDVTRVQARASSPLRTRRGRAQQ >OWK11996.1 CILP2 [Cervus elaphus hippelaphus] MASLPTLLYLCVAAAHLAGARGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLAL EARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCPSP AGDACPGRPSEAQKCVRPRCPGCGPNTCGCPDHILLGSVVTPSGRPLPGARVSFRDWPGTIATSDAHGTFRMPGICASSR ANISAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDR RTHRYGAHLELHGLRPDQAGAYHCKAWNDAGAVRSGIARLTVLAPGQPACDPRPREHLIKLPDDCGQPGRGPTYLDVGLC PDTLCPSPAGSRPRCGEAGSRCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAADSREPLRFARILL GREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEIKAMRKKAPIILDASQSNTISLGEM GDEAPLGELVIPPGAFRRADGQPYTGVVEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRTYGMFSVDLRAAGSAEQ LQTGLVAVRVATDQIRMPGHLEALKLWSLNPDTGLWEEESSFQRERPASQWARREERVFLVGNVEIRERRLFNLDVPERR RCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATLGG EELEPAPSRPRPLPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRSLRECQEAPVTAG HFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGSHPRTQGQLYGLRDS RSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPL GHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPSAALGDIRREMGD VTRVQARASSPLRTRRGRAQQ >KAF4014309.1 hypothetical protein G4228_006190 [Cervus hanglu yarkandensis] MASLPTLLYLCVAAAHLAGARARVVPAEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPS DVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLGCGPNTCGCPDHILLGSVVTPSGRPLPGARVSLRDWPGTIAT SDAHGTFRMPGICASSRANISAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGT PMPKKYSWFHNGTLLDRRTHRYGAHLELHGLRPDQAGAYHCKAWNDAGAVRSGIARLTVLAPGQPACDPRPREHLIKLPD DCGQPGRGPTYLDVGLCPDTLCPSPAGSRPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGR VVAADSREPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEIKAMRKKA PIILDASQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGVVEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLR TYGMFSVDLRASGSAEQLQTGLVAVRVATDQIRMPGHLEALKLWSLNPDTGLWEEESSFQRERPASQRARREERVFLVGN VEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCD ADQPDAYTAVVTATLGGEELEPAPSRPRPLPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPV YPWRSLRECQEAPVTAGHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNL GGSHPRTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPA PSDDLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRL LESPSAALGDIRREMGDVTRVQARASSPLRTRRGRAQQ >XP_018112382.1 cartilage intermediate layer protein 2 [Xenopus laevis] MPALLSSLLIFVFLKISATTGASEWTSWFNVDHPEGEGDYETVEAVRFYYPDRLCSRPIALEARTTEWMAPEDTMEVVHS SPEKGFWCSNKEQKDGNLCSNYHVRFKCPLEDYWSHWEAWTPCTRTCGGGRRIRRRVCTSKKNNCSGRTYQLQKCGKAPC KACDLLCANGESNAACRRCNCDSHTLVGKVQSSRGSALHGARVFLKYELLGTTDLRGNIRIAGICSDDHVNVTVVLDGYT SVTLQNVKNGSSSSYFLALLKREEKPYMVQHPYSKIRKEGQKVTFCCEATGNPIPTKYYWYHNSTLLDKQIFKYDKALTL RNLQAVQTGTYQCRASNGLGVVKSSVAQLTIVGKQENSCSKSPQEHLIKLPAGCFQTTTRSLYHNVGKCPNAQCVGSVSS EILCKDKVDYCCGVKQMMLQEVQCPGYILPIMVVKECGCVKCIQPKVLVRGRVTAYDTGEPLRFGQIFVSGENMGFTGYK GEFTLEVPAGTKRLVVTFIDREDKFVETIKVFPFDPKGSTVYQDVKIMRKSQPKNLDPGIINIIPLGTVEAEDPMAEIVI PPYSFTRTSGEVYNGTVKASVTFLDPRNISTASAASSDLNFVNRDGEIAPLRTYGMFAVDFRQEDTNAILLAGKVEVHLN TEQVKMPQHLKEMKLWSLNEETGMWEEESRFQVVKGGQRKRREERSFLIGQLEIRERRLFNLDVPEHRRCFVKVRAYMNE KFIPSEQLEGVVINLINLEPVAGFSSNPRAWGRFDSVITGKNGACLPAFCDAQRPDAYTAYVTAIMGGEELEAAPSSPKL NPNVVGVSQPYLSKLGYQRSDHEDTAGKKTAFKLNLAKPNPNNLDETSGPIYAYRNLRGCEGAPVSDNHFRFYRVEEDKY EFNVVPFVETDLTSWIGGYLSWWPNPQEFRACYIKIRIQGTQEYMIRSRNAGGSHPRTTGQLYGLRDIRSVRDLHVDRSS AACVEFKCSGMLYDQSVVDRTHVVINPQGSCRIIEINRLLKEYLARHPPVVLGNDTGTFNMLAPVDPLGHNYGIYTVTDQ NPKLAKEIAIGRCFDGTSDGFSREMKSTAGVALTFRCQEKPVTHESFFQRLLNNPGETLREIRRGMLENEQNENLPQVVP YPATGRTTSRTRRPIANQRRPGQVRRN >XP_008267106.1 PREDICTED: LOW QUALITY PROTEIN: cartilage intermediate layer protein 1 [Oryctolagus cuniculus] MAGTKAWVCSFLVLEVASVLGRRPMLTQSVRRVQPGKRTPSILAKPADPSESPGEWTTWFNIDHPGGLGDYERLDAIRFY YGDRVCARPLRLEARTTNWMPAGSNGQVVHGSPHEGFWCLNREQRPGQNCSNYTVRFLCPPGSLRQDSERIWSPWSRWSK CSAACGHTGVQTRTRTCLAESMALCTEATEEGRLCETQACTACDLSCPMGKANADCDACMCQDFLLHGAVSLPGGAPAAG ATVYLLNKTPKLLTQTDSNGRFRVPGLCPDGTTILKIMKTKFAPIVLTMPKTRLNVATVNAEFRRAETPYMLTSPQTKAR RAGQSVSLCCKATGKPSPDKYLWYHNNTLLHPSLYKHESKLVLRNLRQEQAGEYFCKAQSDAGAVKSQVAQLMVIAPDET PCNPVPESYLIRLPHDCFQNATNSFYYDVGRCPVKTCAGQQDNGLRCQDAENCCGISKMKEKEIQCSGYTLPTKVAVQCS CQRCTETRSIVRGRVSAADTGEPMRFGHVYMGNSRVSMTGYKGTFTLHVPQDTERLVLTFVDRLQKFVNTTKVLPFNKKG SAVFHEIKMLRRKEPITLEALETNIIPLGEVDGEDPVAELEIPPKSFFRQNGEPYTGKVKASVTFLDPRNVSTATAAQSD LNFVNDEGDTLPLRTYGMFSLDFTDEATAEPLNAGKVKVHLDSTQVKMPEHVAAMKLWSLNPDTGLWEEEGDFKLESRRR NKREQRTFLVGNMEIRERRLFNLDVPESRRCFLKVRAYRSERFLPSEQIQGVVVSAINLEPRAGFSSNPRAWGRFDSVIT GPNGACVPAFCDDQSPDAYSAYVLASLAGEELEAVESSPKFNPNAIGVPQPYLNKLKYRRTDHEDPQVKKTAFQISMAKP RPNSAEESNGPIYAFENLRACEDAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIV GAVEVNVRSRNMGGTHRRTVGKLYGIRDVKSTRDRDQPNVSSACLEFKCSGMLYDQDRVDRTLVKVIPQGSCQRASVNSM LHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVTDQDPRTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCAE RQVGRQSAFQYLQSTPARTPAAGTGQGRVPPRRQQRARRGGQRQPERPASLRFSGAAQQPPSN >XP_009251325.1 cartilage intermediate layer protein 2 isoform X1 [Pongo abelii] MASLLPLLCLCVVAAHLAGARDATPTEEPMATALGLERRSVYPGQPSPALEDWEARAVPAEASEWTSWFN VDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHLNPTRGFWCLNREQPRGRRC SNYHVRFRCPLEASWGAWGPWGPCSGSCGPGRRLRRRHCPSPAGDACPGRPLEAQKCLRPRCPGCSLDTC ECPDHILLGSVVTPSGQPLPGARVSLRDQPGTVATSDAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQ ANGSISVVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRAHGYGAHL ELRGLRPDQAGIYHCKAWNEAGAVRSGAARLTVLAPGQPACDPRPREYLIKLPEDCGQPDSGPAYLDVGL CPDTRCPSLAGSGPRCGDASSRCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAADS GEPLRFARILLGQEPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDPRGAGVYHEVKAM RKKAPVILDASQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGPVEARVTFVDPRDLTSAASAPSD LRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVAVRVAASQIHMPGHVEALKLWSLNPETGLWEEE SGFRREGSSGPRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVN LEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSLPRPLPATVGV TQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFARVEA DKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTRGQLYGLRD ARSVRDPERPGTSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLRDYLTRHPPPVPAEDPA AFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSL FQRLLESPATALGDIRREMSEVAQAQARASGPLRTRRGRVRQ >XP_003123618.1 cartilage intermediate layer protein 2 isoform X1 [Sus scrofa] MASLPTLLCLCVAAAHLAGARGTTTPEEPTATAWDLEGPSLRPGQPSPALEDWEEASEWTSWFNVDHPGG DGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVR FRCPLEATWGAWGPWGPCSGSCGPGRRLRRRRCPSSAGDACPGRPLEAQKCIRSPCPGCSLNICGCPDHI LLGSVVTPTGRPLPGARVSLRDWPGTVATSNAHGTFRMPGVCASSRVNVSAQMDGFSAGMAQAQANSSIS AVVTVVLKKLEKPYLVKQPESRVREAGQNVTFCCKASGTPIPKKYSWFHNGTLLDRRTHRYGAHLELHGL HPDQAGTYHCKAWNDAGAVRSGTARLTVLAPGQPACDPQPREHLIKLPDDCSQPGSGPTYLDVGLCPDTL CPSATGSSPRCGDAGSRCCSVRRLESRKIRCSGYNLPVKIVAECGCQKCLPRRGLIRGRVVAADSGEPLR FARILLGREPIGFTSYQGDFTLEVAPSTQRLVITFVDTSGQFVDTVRVLPFDPRGAGVYHEVKAMRKKAP VILDASQSNTIPLGELEDEAPLGELVIPPGAIRRADGEPYVGSVEARVTFVDPRDLTSAAAAPSDLRFVD SDGELAPLRTYGMFSVDLRAPDSTEQLQTGPVAVRVAASQIRMAGHVEALKLWSLNPDTGLWEEESGFQR ERSAAQRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPNEQVEGVVVTLVNLEPAP GFSANPRAWGRFDSAVTGPNGACLPAFCDTDRPDAYTALVTATLGGEELEPATSRPRPLPATVGVAQPYL DKLGYRRTDHDDPSLKRNGFRINLAKPRSGDPDEANGPVYPWRNLRECQEAPVTANHFRFARVEADKYEY NVVPFREGVPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTQGQLYGLRDARSVR DPERPSMSAACVEFKCGGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPADDLAAFSML APLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPAAGRPSLFQRLL ESPSTALGDIRREMGEVARAQARASVPLRTRRGRARQ >XP_003817771.2 cartilage intermediate layer protein 2 [Pan paniscus] MGRGQGGICGRIPPPLSVPAAARPAGVGPEHAAEPGPSLGRSAPAMASLLPLLCLCVVAAHLAGARDATP TEEPMATALGLERRSVYTGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLA LEARTTDWALPSAVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEASWGAWGPWGPCSGSCGPG RRLRRRHCPSPAGDACPGRPLEAQKCVRPRCPGCSLDTCECPDHILLGSVVTPSGQPLLGARVSLRDQPG TVATSDAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQANGSISVVTIILDKLEKPYLVKHPESRVREA GQNVTFCCKASGTPMPKKYSWFHNGTLLDRRAHGYGAHLELRGLRPDQAGIYHCKAWNEAGAVRSGTARL TVLAPGQPACDPRPREYLIKLPEDCGQPGSGPAYLDVGLCPDTRCPSLAGSSPRCGDASSRCCSVRRLER REIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAADSGEPLRFARILLGQEPIGFTAYQGDFTIEVPP STQRLVVTFVDPSGEFMDAVRVLPFDPRGAGVYHEVKAMRKKAPVILHASQSNTIPLGELEDEAPLGELV LPSGAFRRADGKPYSGPVEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQ LQVGPVAVRVAASQIHMPGHVEALKLWSLNPETGLWEEESGFRREGSSGPRVRREERVFLVGNVEIRERR LFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPA FCDADRPDAYTALVTATLGGEELEPAPSLPRPLPAAVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAK PRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQE FRACFLKVKIQGPQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERPGTSAACVEFKCSGMLFDQRQV DRTLVTIMPQGSCRRVAINGLLRDYLTWHPPPVPAEDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEI AIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMSEVAQAQARASG PLRTRRGRVRQ >XP_003982175.1 cartilage intermediate layer protein 2 [Felis catus] MASLPPLLCLFVAAAHLAGARVTTPPEEPTATAWGFEGPSLRPGQPSPALEDWEEASQWTSWFNVDHPGG DGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSTVGERVHLNPTRGFWCLNREQPRGRRCSNYHVR FRCPLEATWGAWGPWGPCSGSCGPGRRLRRRRCPSPSGDACPGRPLEAQKCVRPPCPGCSSKTCTCPDHI LLGSVVTPSGRPLPGARVSLRDWPGTVAITDAHGTFRIPGVCASSRANISAQMDGFSAGLGQAQANGSIS AVVTVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRREHRYGAHLELRGL RPDQAGTYHCKAWNDAGTVRSGSARLTVLAPGQPACNPQPQEHLIKLPDDCGQPGSGPAYLDVGLCSDTL CPSPAGSSSRCGDSGSRCCSVRRLESKEIHCSNYVLPVKVVAECGCQKCLPPRGLVRGRVVATDSGEPLR FAQILLGREPIGFTSYQGDFTIEVPPSTQRLVVTFVDPSGEFMDTVRVLPFAPRGGGVYHDVKAMRKKAP VILDASQSNTIPLGELEEEDPLGELVLPPGAFRRADGAPYTGAVEARVTFVDPRDLTSAAAAPSDLRFVD SDGELAPLRTYGMFAVDLRAAGSAEQLQAGPVAVRVNAGQIHMEGHVEALKLWSLNPDTGLWEEESGFQR EGSAAPRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPNEQVEGVVVTLVNLEPAP GFAANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSRPRPHAATVGVAQPYL DKLGYRRTDHDDPALKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQEAPVTASHFRFARVEADKYEY NVVPFREGVPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTQGQLYGLRDARSVR DPEHPGTSAACVEFKCSGMLFDQRQVDRTLVTITPQGSCRRVAVNGLLRDYLARHPPAAPADDPAAFAML APLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLL ESPATALGDIRREMGEVTRAQAQAAGPLRTRRGRARQ >XP_027825142.1 cartilage intermediate layer protein 2 [Ovis aries] MASLPTLLWLCVAAAHLAGARGTPDAEEPTVTAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGG DGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRSCSNYHVR FRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCPSPAGDACPGRPSEAQKCVRPRCPGCGPNTCGCPDHI LLGSVVTPSGHPLPGARVSLRDWPGTVATSDAHGTFRMPGVCASSRANVSAQMDGFSAGMAQAQANSSMS AVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELHGL RPDQAGTYHCKAWNDAGAVRSGTARLTVLAPGQPACDPRPQEHLIKLPDDCGQPGRGPTYLDVGLCPDTL CPSPAGSSPRCGDAGSRCCSVSRLESRKVHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAADSSEPLR FARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEVKAMRKKAP IILDARQSNTISLGEMGEEAPLGELVIPPGAFRSADGQPYTGAVEAQVTFVDPRNLTSAAAAPSDLRFVD ADGELAPLRTYGMFSVDLRAAGSAEQLHTGLVAVRVAADQIRMPGHVEALKLWSLNPDTGLWEEESGFQR ERPASRRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFSPSEQVEGVVVTLVNLEPAP GFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTAVVTATLGGEELEPAPSRPRPLPAAVGVAQPYL DRLAYRRTDHDDPALKRSGFRINLAKPRPGDPSEANGPVYPWRSLRECQEAPVTASHFRFARVEADKYEY NVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGTHPQTQGQLYGLRDSRSVR DPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTVMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSML APLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLL ESPSAALGDIRREMGQASRVQARASGPLRTRRGRAQQ >KYO23576.1 cartilage intermediate layer protein 2 [Alligator mississippiensis] MRESECPTVVSVSGTEWTSWFNIDHPGGDGDYETLEAIRFYYQGRVCAQPLALEARTTEWELPRDVGEFVHASPRKGFWC INQEQPEGRTCSNYHVRFLCPLACQLTCAAGKANKDCSGCTCPDHTLLGTVVSAEGSALANARVALQDRPQATLARTDQR GRFRVPGVCAGSAANVTVQLERFSPGAAPVIASGPQTSTVQVTLRRLEKPYMVMHPDSKVRTAGQQVTLCCKASGTPVPR KYYWYHNGTLLDRKVYRYDGRLVLKELQPRHAGAYHCKASSDAGAIKSAIARLTVLGKGQPSCRARPEQSLIRLPGECFP DASGSPYYDVGRCPATRCAGSLAEKRQCRDDKERCCGVRRMELREVRCAGYVLPIKVVAECGCETCAQPKVLVQGRVVAA DDGEPLRFGQVFLGQKSIGFTGYQGAFTIEVPPGTRRLVVRFVDPLQKFLDTVKVLPFDSQGSAVYQDVRVMRKKTPMDL DAAQTNALPLGELAGEGPVGELVFPAGAFRRASGEPYNGTVKASVTFLDPRDAATVATASSDLSFVNAEGDMVPLRTYGM FAVDLRARAGGERLQASGVEVRMDAGQVRMPEHLPKMKLWSLNPTTGLWEEEGALRPAPARRGKREERTFLVGNLEIRER RLFNLDVSENRRCFVKVRAYGSEKFSPLEQLQGVVVTLVNLEPRPGYPANPRAWGRFDSAVTGRNGACLPAFCDGQRADA YTAYVTATLGGEELEAAASRPSPDPSTVGVSQPYLSKLGYRRLDHTDPRAKKTAFRVNLAKPNPNNVDEVNGPLYPYRSL RECEEAPVSANHFRFSRAEVDKYEYNVVPFEEGDLTSWTRDYLAWWPNPQEFRACYIKVKVEGPQEYMVRSRNVGGSHPW TQGQLYGLRDARSVKDPELEHSSAACVEFKAAATARPPTASCGST >XP_018871353.1 cartilage intermediate layer protein 2 isoform X1 [Gorilla gorilla gorilla] MASLLPLLCLCVVAAHLAGARDATPTEEPMATALGLERRSVYPGQPSPALEDWEARAVPAEASEWTSWFN VDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHLNPTRGFWCLNREQPRGRRC SNYHVRFRCPLEASWGAWGPWGPCSGSCGPGRRLRRRHCPSPAGDACPGRPLEAQKCVRPRCPGCSLDTC ECPRHILLGSVVTPSGQPLLGARVSLRDQPGTVATSDAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQ ANGSISVVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRQAHGYGAHL ELRGLRPDQAGIYHCKAWNEAGAVRSGTARLTVLAPGQPACDPRPREYLIKLPEDCGQPGSGPAYLDVGL CPDTRCPSLAGSSPRCGDASSRCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRIVAADS GEPLRFARILLGREPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDPRGAGVYHEVKAM RKKAPVILHASQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGPVEARVTFVDPRDLTSAASAPSD LRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVAVRVAASQIHMPGHVEALKLWSLNPETGLWEEE SGFRREGSSGPRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVN LEPAPGFSVNPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSLPRPLPATVGV TQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFARVEA DKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTRGQLYGLRD ARSVRDPERPGTSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLRDYLTRHPPLVPAEDPA AFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSL FQRLLESPATALGDIRREMSEVAQAQARASGPLRTRRGRVRQ >XP_011471792.1 cartilage intermediate layer protein 2 [Oryzias latipes] MRRSSSKTRPSASLLSVDFKLDIRKLRKKLFNHPEICINAVENLSKEISFVRTMLELNKLRLLLSLLAYV TLGQGSLRTRNISDRSKRTASNRFSDTQRTGVTEWTSWFNIDHPGGNGDYERLEAIRFYYRERVCSRPTA IEARTSDWLTAADTGEVVHSSLEKGFWCINKEQPKGNICSNYHVRFQCPPVQSYWTEWSEWGPCSATVCS DVGIQVRQRKCLSSQPMPLLFVPACQGHHSERRECSTPQCTAKWSPWGHWGMCSVTCGGGQRTRRRTCVR TSVSVQCAGRSVDIQKCGKTPCPAKCQLVCEEGHPSEDCSLCVCEDHVLHGDVHSVTGVPVEGARVSLAS HSKALHAQTNAKGQFVLAGVCSSTSSSIIIKKEKYVPTIVSTSSNTTGLSRLKAVLRSAEKPYVVKHPED KVRYEGGRVLLCCSATGSPAPSKYYWYHNGTLLDRKIYKYEEDLMLQDLKFEHSGEYYCKTSNPAGSIKS SVAILSVIAKGTPACDSTPEAHLIRLPLDCVQPGTQSKYYNAGRCPHNKCAGSLEFDMRCKDGAGFCCGV QSMESRVIDCGSYSLPIRAVTKCICQKCMQPTVIVRGRVVTADNNEPLRFGHIYIGKERVGTTGYQGGFT LKIAQDTQRLVVNFVDPTETFLNTPKVFIFDKKSGSIYHDVKVMRKQKPIDINSRETNVIDLGEIKGEDP IGQLVIPPNSFHKDTGEVYEGTVKASVTFIDPRNITTAAATPGDLNFVDDEGDMLPLRTYGMFSVDFRDN SSNKVLGAGAVQVLLDTQHVKMQEHIPQMKLWSLNPDTGVWEEESKFSYSTTTADGHGRSKREERTFLIG NMEIRERRLFNLDVPESRRCYVKVRAYMSDKFLPTEQLEGVVITLINLEPKPGYSSNPRAWGRFDSVITG PNGACLPAFCDAMRPDAYTAYVTAMLNGEELEAAPSTPKMNPNIIGVSKPFLDKLDYQRSDHTDSALKKT AFKINLAKPNQNNLDETNGPIYPYQSMIACENAPIDANHFRFFRVEKDKYEYNVVPFEENDLTSWTGDYL SWWPNPQEFRACFIKVRIHGQKEVMVRSRNHGGTHPETKDKLYGIRDIRSTRDMREANTSAACVEFKCSG MLYDQSEVDRSLISVLPQGNCRRININNLLQEYLIKHPPFTQSNGSHSFTMMAPVDPLGHNYGIYTVTDQ NPRVAKEIAIGRCFDGTSDGFSREMKSDSGVALTFSCPERKINRQSLFQRLQTNPGQTLSQMARDMRDFQ GEQRQRSATQVVFPSEQRGRTQSRRMSSGARRTVPVREQQYQ >XP_005505580.2 LOW QUALITY PROTEIN: cartilage intermediate layer protein 2 [Columba livia] MENDSEPGKSDGGRKPWKAAPSLAELDLDTAGRGAEWTSWFNIDHPGGDGDFESLDAIXXXXXXXXXXAI QARTTAWELPEEVGEVVHASPKKGFRCLNKEQPQGKTCSNYHIRFLCPLEKPYMVLHPKAKVRVAGQEVT FCCKASGTPVPKKYYWYHNGTLLDRKVLRYGSRLVLRGVTPEQTGTYHCKASTEAGVTKSAPAQLTVLAQ GQQSCKPEPEPSLVELPSECPQDATGSRYYNVGRCPPTPCPGSPAKESGCGGGPGRCCGVRRMELREIPC AGSLLPVKVVAECGCGPCAQPRVLVQGRVTAADTGEPLRFGQIFLGGRKVGFTGYKGSFTIEVPPDTQRL VVRFVDRHQRFIDAIKVLPFDRRGGTVYQEVKMLRKKEPVELDSNQSNVIPLGEARGQEPIGELVLPAGT FLHPSGEVFKGTVKASVTFLDPRDMATASAASSDLSFTNAEGEIVPLRTYGMFAVDFQEGETGAALQTGP VEVRMDAGQVWMPEHLQKMKLWSLNPETGLWEEEGVLXXXXXXKREERTFLVGNLEIRERRLFNLDVPED RRCFVKVRAYANEKFNPYEQLEGVVISLINLEPQPGYPANPRAWGRFDSVVTGPNGACLPAFCDSQRPDA YSAYVTATLGGEELEAVASSPKLNPNTIGVSQPYLGKLGYRRSDHDDPNLKKTAFQINVAKPDPNNVDET NGPIYPYRSLEECEEAPVSANHLRFYRVEVDKYEYNVVPFKESDLTSWTGDYLSWWPNPQEFRACFIKVQ IEGPQEYMVRSRNLGGTHPRTRGQLFGLRDTRSVRDMLLENTSGACVEFKCSGMLFDQSLVDRTLVSIIP QGSCRRTAVNSLLRDYLSRHPPVAENNHTAAFTMLAPVDPLGHNYGIYTVTDQNPRLAKEIAIGRCFDGT SDGFSREMKADTGTAVTFTCQERPAGRQSFFQRLLTAPAQALDEIRREMGAGEMRRAPPDVMDFASGAQA PRPSAARRTPSSRQRTGRSRGEP >XP_017906987.1 PREDICTED: cartilage intermediate layer protein 2 [Capra hircus] MASLPTLLCLCVAAAHLAGARGTPDAEEPTVTTWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGG DGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRSCSNYHVR FRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCPSPAGDACPGRPSEAQKCVRPRCPGCGPNTCGCPDHI LLGSVVTPSGRPLPGARVSLRDWPGAVATSDAHGTFRMPGVCASSRANISAQMDGFSAGMAQAQANSSMS AVATVVLNKLEKPYLVKHPESRVRQAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELRGL RPDQAGTYHCKAWNDAGAVRSGTARLTVLAPGQLACDPRPQEHLIKLPDDCGQPGRGPTYLDVGLCPDTL CPGPAGSSPRCGDTGSRCCSVRRLESRKIHCSGYTLPVKVVAECGCQKCLPLRGLIRGRVVAADSSEPLR FARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEVKAMRKKAP IILDARQSNTISLGEMGEEAPLGELVIPPGAFRRADGQPYTGAVEAQVTFVDPRNLTSAAAAPSDLRFVD ADGELAPLRTYGMFSVDLRAAGSAEQLHTGLVAVRVAADQIRMPGHVEALKLWSLNPDTGLWEEESGFQR ERAASRRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAP GFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTAVVTATLGGEELEPAPSRPRPLPAAVGVAQPYL DRLAYRRTDHDDPALKRSGFRINLAKPRPGDPTEANGPVYPWRSLRECQEAPVTASHFRFARVEADKYEY NVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGTHPRTQGQLYGLRDSRSVR DPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTVMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSML APLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPAAGRPSLFQRLL ESPSAALGDIRREMGQASRVQARASGPLRTRRGRAQQ >XP_025052336.1 cartilage intermediate layer protein 2 [Alligator sinensis] MGALAPALLFLAALHCAGARAEPEENDSRLAKTKPPGKRRKKVPNGTSPDVDTAGTEWTSWFNIDHPGGD GDYETLEAIRFYYQGRVCAQPLALEARTTEWELPRDVGEFVHASPRKGFWCVNQEQPEGRTCSNYHVRFL CPLEATWGPWGAWSPCSKTCGSGGRRLRRRSCKKSRTSRCAGRPSEVQKCARTPCPACQLTCATGKANKD CSGCTCPDHTLLGTVVSAEGSALANARVTLQDRPQATLARTDQRGRFRVPGMCAGSTANVTVQLERFSPG AAPVIASGPRMSTVQVTLRRLEKPYMVMHPDSKVRTAGQQVTLCCKASGTPVPRKYYWYHNGTLLDRKVY RYDGRLVLKELQPRHAGAYHCKASSDAGAIKSAIARLTVLGKGQPSCRARPEQSLIRLPGECFPDASSSP YYDVGRCPATRCAGSPAEERQCRDDEERCCGVRRMELREVRCAGYVLPVKVVAECGCDQVFLGQKSIGFT GYQGAFTIEVPPDTRRLVVRFVDPLQKFLDTVKVLPFDSQGRAVYQDVPELEAAASRPSPDPSTVGVSQP YLSKLGYRRLDHTDPRAKKTAFRVNLAKPNPNNVDEVNGPLYPYRSLRECEEAPVSANHFRFSRAEVDKY EYNVVPFEEGDLTSWTRDYLAWWPNPQEFRACYIKVKVEGPQEYMVRSRNVGGSHPWTQGQLYGLRDARS VKDPELEHSSAACVEFKCSGMLFDHSGMDRTLVSIVPQGSCYRTATNSLLREYLGRHPPAAPNNDTRAFH MLAPVDPLGHNYGIYTVTDQNPRLAKEIALGRCFHGTSDGFSREMKSEVGTAVTFLCQERPAGRQSLFQR LLEAPAEDLTEIRQEMGRSGQP >XP_015827098.1 PREDICTED: cartilage intermediate layer protein 2 [Nothobranchius furzeri] MHFLKMLELTKLALLLSFLTSVALGQGSVRSRMLSDRSKRTTFQAFSDPQTTGVTEWTSWFNIDHPGGNG DYERLEAIRFYYRERVCVRPTAMEARTTDWVAAADTGEVVHSSLEKGFWCINKEQPLGRACSNYHVRFQC PPVQSYWTDWSEWGPCSTTACNDVGIQLRQRKCVSAQPMPLLFVPACQGHHSERRECTTPPCTAKWSPWG PWGMCSVTCGGGRRTRRRTCERTSATIQCKGRPVEVHKCGKSPCPANCQLVCSEGRPSEDCSSCVCEGHM LQGDVQGVAGFPIAGAAVGLASLPQVIRARTDAKGQFRLPGVCSSSSMLLTIRKEKFVPINVSTSSNTTG LSWLRAVLKSAEKPYIVKHPEDKVRYEGGRLLMCCTATGSPAPDKYYWYHNGTLLDRRVYKYEEDLVLRD LKLEQSGEYYCKASSPAGSIKSAPALLTVVGKGTPACNSTPEFHLIRLPMDCIQLGTDSKYYNAGRCPHN QCAGSLDYDMRCRDGAGFCCGVQKMESRIIDCGNYKLPIRAVSHCGCQKCMQPTVLVRGRVVTADNGEPL RFGHIYIGKERVGTTGYQGGFTLQITPDTQRLVVNFVDPTQRFLDTPKVFILDKKGGSIYHDVKVMRKQT PIDIDAGETNFIDLGEIKGEDPIGQLVIPPNSFHKDNGETYEGTVKASVTFIDPRNITTAAAAPGDLNFV DDEGDMLPLRTYGMFSVDFRDESNKEVLGAGAVQVLLDTQHVKMQEHIPEMKLWSLNPDTGVWEEESDFS YSTTTAGGHGRSKREERTFLIGNMEIRERRLFNLDVPESRRCYVKVRAYMSDKFLPTEQLEGVVISLINL EPKPGYSSNPRAWGRFDSVLSGSNGACLPAFCDAMRPDAYTAYVTAMLGGEELEAAPSSPKMNPNIIGVS QPYLDKINYQRSDHDDPALKKTAFKINLAKPNQNNFDETNGPIYPYQNLLGCENAPVDANHFRFFRVEKD KYEYNVVPFEETDLTTWTRDYLSWWPNPQEFRACFIKIKIHGQKEVMVRSRNLGGTHRETRGKLYGIRDI RSTRDMREANTSAACLEFKCSGMLFDQAEVDRSIISVLPQGNCRRISINGLLQEYLIKHPPVAQNNESHA FTMLAPVDPLGHNYGIYTVTDQNPRVAKEIAIGRCFDGTSDGFSREMKSDYGVAVTFSCPEKKINRESLF QRLQTNPGQTLAQMARDMRELEGMQVQRSSTQVVAFPSEQQGRTQSRRVSSTARRRASIRAQQRQ >XP_016792564.1 cartilage intermediate layer protein 2 [Pan troglodytes] MGRGQGGICGRIPPPLSVPAAARPAGVGPEHAAEPGPSLGRSAPAMASLLPLLCLCVVAAHLAGARDATP TEEPMATALGLERRSVYTGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLA LEARTTDWALPSAVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEASWGAWGPWGPCSGSCGPG RRLRRRHCPSPAGDACPGRPLEAQKCVRPRCPGCSLDTCECPDHILLGSVVTPSGQPLLGARVSLRDQPG TVATSDAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQANGSISVVTIILDKLEKPYLVKHPESRVREA GQNVTFCCKASGTPMPKKYSWFHNGTLLDRRAHGYGAHLELRGLRPDQAGIYHCKAWNEAGAVRSGTARL TVLAPGQPACDPRPREYLIKLPEDCGQPGSGPAYLDVGLCPDTRCPSLAGSSPRCGDASSRCCSVRRLER REIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAADSGEPLRFARILLGQEPIGFTAYQGDFTIEVLP STQRLVVTFVDPSGEFMDAVRVLPFDPRGAGVYHEVKAMRKKAPVILHASQSNTIPLGELEDEAPLGELV LPSGAFRRADGKPYSGPVEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQ LQVGPVAVRVAASQIHMPGHVEALKLWSLNPETGLWEEESGFRREGSSGPRVRREERVFLVGNVEIRERR LFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPA FCDADRPDAYTALVTATLGGEELEPAPSLPRPLPATVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAK PRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQE FRACFLKVKIQGPQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERPGTSAACVEFKCSGMLFDQRQV DRTLVTIMPQGSCRRVAINGLLRDYLTRHPPPVPAEDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEI AIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMSEVAQAQARASG PLRTRRGRVRQ >XP_020766171.1 cartilage intermediate layer protein 2 [Odocoileus virginianus texanus] MASLPTLLCLCVAAAHLAGARGTPDTEEPTVAAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGG DGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVR FRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCPSPAGDACPGRPSEAQKCVRPRCPGCGPNTCGCPDHI LLGSVVTPSGRPLPGARVSLRDWPGTIATSDAHGTFRMPGICASSRANVSAQMDGFSAGTAQAQANSSMS AVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELHGL RPDQAGAYHCKAWNDAGAVRSGTARLTVLAPGQPACDPRPREHLIKLPDDCGQPGRGPTYLDVGLCPDTL CPSPAGSRPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAADSREPLR FARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEIKAMRKKAP IILDASQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGAVEAQVTFVDPRNLTSVAAAPSDLRFVD RDGELAPLRTYGMFSVELRAAGSAEQLQTGLVAVRVATDQIRMPGHLEALKLWSLNPDTGLWEEEGGFQR ERPASQRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAP GFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATLGGEELEPAPSRPRPLPATVGVAQPYL DRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRNLRECQEAPVTASHFRFARVEADKYEY NVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNVGGSHPRTQGQLYGLRDSRSVR DPQHPSSSAACVEFKCSGMLFDQRQVDRTLVTVTPQGSCRRVAVNGLLQDYLARHPPSAPAEGLAAFSML APLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLL ESPSAALGDIRREMGDVARVQARASSPLRTRRGRAQQ >XP_030289610.1 cartilage intermediate layer protein 1-like [Sparus aurata] MLGLNKVALLLSFMASLALGQGSVRTRRQLDRSRRVALNTFTDTQTTGVTEWTSWFNIDHPGGNGDYERL EAIRFYYRERVCVRPMAMEARTTDWVAAADTGEVVHSSLEKGFWCINKEQPHGRICSNYHVRFQCPPVQS YWTDWSEWGPCSTTDCDDVGIQVRQRKCVNTQPMPLLLVPACQGHHSERRECSTALCTAKWSPWGRWGTC SVTCGGGRRIRRRTCVRTSLTIQCTGRPVEVQKCGKSPCPAKCQRVCTEGRPSEDCSRCVCDSHVLQGEV LTVTGVPVAGALVALASQPKAIRARTDAKGQFGLKGICSSSSTLISIRKEKYAPVTVSTSSNTTGLSWVQ ALLKSAEKPYIVKHPEDKVRYEGGRVLLCCKATGSPAPDKYYWYHNGTLLDRKVYKYEEDLVLRDLKPEQ SGQYYCKTSSPAGSIKSSPSLLTVIAKGTPACNSTPETHLIRLPMDCVQPGTVSKYYNAGRCLLNKCAGS LDFDMRCRDGSAFCCGVQNMESRIIDCGSYSLPIRAVTQCGCQKCVQPTVLVRGRVVTADNNEPLRFGHI YIGKERVGTTGYQGGFTLQISPDTQRLVVHFVDPTQKFLDTPKVFILDKKGGSIYHDVKVMRKQMPIDIN AGEINSINLGEIKGEDPIGQLVIPPNSFHKDNGEIYEGTVKASVTFIDPRNITTAAAAPGDLNFVDDEGD MLPLRTYGMFSVDFRDETNKEVLGAGAVQVLLDTQHVKMQEHIPKMKLWSLNPDTGVWEEESDFYATQTT GGHGRSKREERTFLIGNMEIRERRLFNLDVPENRRCYVKVRAYMSDKFLPTEQLEGVVISLINLEPKPGY SSNPRAWGRFDSVITGPNGACLPAFCDAQRPDAYTAYVTAMMGGEELEAAPSSPKMNPNIIGVSQPYLDK IDYQRSDHEDPALKKTAFRINLAKPNQNNLDETNGPIYPYQNLIACENAPIDANHFRFFRVEKDKYEYNV VPFEENDLTTWTGDYLSWWPNPQEFRACFIKVKIQGQKEVMIRSRNLGGTHRETKAKLYGIRDIRSTRDM REANTSAACVEFKCSGMLFDQAEVDRSLISVLPQGNCRRINTNSLLQEYLIKHPPVAQNNESHAFTMLAP VDPLGHNYGIYTVTDQNPRVAKEIAIGRCFDGTSDGFSREMKSDSGVALTFSCPERKINRESLFQRLQTN PGQTLSQMARDMRESEGLQAQRLSSQVVAYPSEQQGRSQSRRVSSTTRRRVSTRIQRRQ >XP_040176473.1 cartilage intermediate layer protein 2 isoform X1 [Rana temporaria] MLACHFALLLSVLFTSALGATDWTSWFNVDHPGDDGDFETIEAIRFYYPHRLCLRPVAIEARTTEWATPK DTKEVVHTDPEKGFWCINKEQKKGYNCSNYHVRFQCPLDLLYWSHWTPWSTCSPTSCGGMGIQIRRRSCI TVQPAVTLSLEKCLGEATERRVCVSSSCVGRWSSWGAWTPCTKTCGGGKSVRRRICSSKTAPCSGRTFQI QKCGRTLCRETSELCPGCHCNNHTLLGKIQSIHGFVLHNAKVFMNKKILGVTDQHGLFMLKGVCMDTPSN ITIKMDGFSSVTLQSMRKEPKVSYFEAALKKLEKPYMVQNPYSKIRRIGHKVTMCCEATGNPVPTKYYWY HNGTLLDKHTLKYDKSLTLRNIQATHGGIYQCKASNGVGVIRSSVAHLNVISKSESLCNKSPNEHLIKLP MDCFQNKTGSYYYNVGRCPNTQCMDHLSSNLQCKDEINYCCGVKQMKLQEVKCPGYILPVMVVVQCGCAE CSRYKIMVRGRVTAYDTGEPLRFGQIFLSGENKGFTGYKGDFTLEVPEGTKRLVVTFVDRQEKFVETTKV IPFDPKGNTVYQDVKVMRKKDPTDLNPRVTNIISLGDLLGEDPIGEIIIPPNSFRRTSGEPYNSTVKASL TFLDPRNISSASAASSDLNFVSRDGDISPLRTYGMFHLDFREDSTNSLLQTGKVEVRLDVEQIKMPQHVK EMKLWSLNPQTGLWEEESHFRLPSGDKRKKREERSFLIGQLEIRERRLFNLDVPEFRRCFVKVRTFMNEK FMVNEQLEGIVVTLINLEPMPGFSSNPRAWGRFDSVVTGSNGACLPAFCDAVKPDAYSAYVTATMGGEEL EAAPSSPKRNPNVIGVTQPYLSKLNYQRTDHDDSAGKKTAFKINLAKPNPNSLAENRGPIYAYRNLQGCE EASILDNHFRFFRAEEDKYEYNVVPFDETDLTSWIGSYLSWWPNPQEFRACYIKIGIQGPQEYMVRTRNI GGTHTHTVGQLYGLRDTRSVRDLEVESSSAACLEFKCSGMLFDQDLVDRTLVTVTPQGSCHVTKINRLLE EYLSRHPPLALGNNTETFNMLAPVDPLGHNYGIYTVTDQNPRLAKEIAIGRCFDGTSDGLSREMKSQVGI AVTFRCQEKPITRKSLFHRLLNNPGETLSEIRQNMQENEQRGTPARVVPYPALQSSSFSQSRKPSASQRR PRMAQSG >XP_039261724.1 cartilage intermediate layer protein 1-like [Styela clava] MQNVIRCKIFISWAVLAFLGIAATQSYVGGNGGYANITSVVPKFKPWREWSTWSQCDVSCGGVGMQERVRKCRNRQDKSS KCFGREIIESRPCGDAPCGTNTVSCDTVGTVTDSLNIPLEGVEICLGSIKVQKCITITHTNEEGFFSVEGICADSEYAHL LARKNKYVTTRIRLKVNETGRAFATVKLLELVKPTIYYHPESKSRMIGQSVKFCCKARGSTKDHLFTWYHNGNVVDANLY SRDPGTLEIRTLRLDDAGEYWCKVSSKTSFAKTTSLSQTAVLSVFESEQNACDEKPGVKLIRLPNDCSMASSRVVQRNNK TYFDVGMCSSVECPAKYADISEGCGETMADITCCGPSERKEINLNCRDFVLPIYKTTKCGCQECVKPVIKVRGRAYGNDP ITDPLRYGYVERSGKRIGRTSYDGGFTVNVPHGSKRLVLTFIDRFGKLMTTTKVVSFKEDGGVTFHDIKMPQKSPEKSFG SQERSVTSLNGVRGQNSVAQIVTAPNGFVRKDGKPYTGKVRASVTFIDPRNETSYQESPTDLAFIDDNGESLPLQTYGMF EMDFRDEDLNELNVANAKIVLDQNQMVSTSHARKLKLWSLNLENGMWEEEENFKEMEIEDEQVQPGPKRKKREAPTTFFV GNLEVRERRLYNLDVPVENRCWLKVRAYRSPDFDPNEQVEGVDIVAINMEPKGGFRGNPSAWGRFDSTLTSKYGACVRVF CHEDKPDVYKAIVTATLDSSEELYAAPSGHPVNPKVVGVQGDILRALDYRRSDHSLATGKKTSFQINLPKPRPEVNYTGP IYPEENYAECVRAPVTDNHFRFYRTEDFLYEYNTVYMDEHNCITWTPHYLNWWPKPLEYRACYIKVHVSGLSTVIRAKSM GGTHPETRGKLYGIRDDRSVLAQRLEGPFIGDSAACIEFKCSGKLYDMEEPDRTLVSVIPQGECQLHRMNGQLSQYLTEH PPAVEGESASEFRMYAPPDPLGHNYGIYTVTDDDPLIAKKTALGRCYAGSSDTTSRIMHARKGVAIYYWCTDRNGEIELP
Mafft alignment of selected proteins >sp|Q8IUL8|CILP2_HUMAN Cartilage intermediate layer protein 2 OS=Homo sapiens OX=9606 GN=CILP2 PE=2 SV=2 ---------------------------------------------------------MAS LLPLLC--LCVVAAHLAGARDATPTEEPMATALGLERRSVYTGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EASWGAWGPWGPCSGSCGP-GRRLRRRHC --PSPAGDACPGRP-LEAQKCVRPRCP----------------GC-----------SLDT CECPDHILLGSVVTPSGQPLLGARVSLRD---QP-GTVATSDAHGTFRVPGVCADSR-AN IRAQMDGFSAGEAQAQANGSIS-VVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRAHGYG-AHLELRGLRPDQAGIYHCKAWNEAGAVR----SGT ARLTVLAPGQPACDPRPREYLIKLPEDCGQPGS------GPAYLDVGLCPDTRCPSLAGS -SPRCGDASS--RCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAAD S-GEPLRFARILLGQEPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDP RGAGVYHEVKAMRKKAPVILHTSQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGP VEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVA VRVAASQIHMPGHVEALKLWSLNPETGLWEEE------SGFRREG-------SSGPRVRR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATL-GGEELEPAPSLPRP LPATVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLREC QGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERP----GTSAACVEFKCSGMLFDQR QVDRTLVTIMPQGSCRRVAVNGLLRDYLTRHPPPVPAEDPAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPA TALGDIRREMSEAAQ------------------AQ-ARASGPL----RTRRGRVRQ---- >tr|F1Q5N7|F1Q5N7_DANRE Cartilage intermediate layer protein 2 OS=Danio rerio OX=7955 GN=cilp2 PE=4 SV=3 ---------------------------------------------------------MWD FTVVTL--VLSTVFVVSLAQG--PIWDSS-RLRRLNQTDRNRKLAYNTLVEPQ----TTG VTEWTSWFNIDHPGGNGDYERLEAIRFYY-RERVCSRPVAMEARTTDWVAAADTGEVVHS SLEKGFWCINKEQPFGRSCSNYHVRFQCPPVHSYWTDWSEWTPCSATACNDVGIQVRQRK CMSTQPLPLLLSPVCVGPHIERRECSTPPC-QAMWSQWGSWGACSVTCGK-GRRTRRRTC H-RSSTKIQCTGRP-IEVQKCG-NPCPV---------------KCKRVCPGGRPDKSCSY CICDGQALHGEVFSITGVPVMNATVALAS---QAKIIRAHTDAKGQFKMDGLCISPQ-TQ IVIRKDKFAPATLPVSNNSTDELWVRAILQSSEKPYIEKHPEDKVRYEGQRATLCCRATG SPKPDKYYWYHNGTLLNRTIFKYD-EDLILRDLKPEQSGQYHCKATSLTGSIK----STS AVLTVFTKGTPACKSTPETHLIKLPLDCKQPGT------DSKFYNAGRCPHNKCPGALDF -DMRCRDGTG--FCCGVKEMDAKEINCGRYTLPIKVVSECGCQTCVEPKVLVRGRVVATD N-DEPLRFGHIYIGKERIGTTGYQGGFTIQVSPETQRLVVNFVDPSQKFIDTIKVFIFDK RGGAVYHDVKVMRKQEPIDINAAESNTIYLGEMKDEDPIGQLVIPPNSFHKNTGEVYEGT VKASVTFLDPRNITMAAAAPGDLNFVDDEGDMLPLRTYGMFSVDFRDGENQEVLGAGAVQ VLLDTEHVKMQEHIPAMKLWSLNPDTGIWEEE------SNFQPTQ----STIAGTGRNKR EE-RTFLIGNMEIRERRLFNLDVPENRRCYVKVRAYMSDKFLPNEQLEGVVINLINLEPK PGYSSNPRAWGRFDSVITGPNGACLPAFCDAQRADAYTAYVTAIM-GGEELEAAPSMPKM NPNIIGVSQPYLGKLDYQRSDHEDSALKKTAFRINLAKPNPNNFDETNGPIYPFQSLIAC ENAPVDANHFRFFRVEKDKYEYNVVPFQESDLTSWTGDYLSWWPNPQEFRACFIKVKIHG ATEIMVRSRNLGGTHPQTRGQLYGIRDIRSTRDLHHP----NTSAACLEFKCSGMLFDQG SVDRSLISVIPQANCRRIGINSLLQEYLIKHPPVLQNNESHAFNMLAPVDPLGHNYGIYT VTDQNPRVAKEIAIGRCFDGTSDGFSREMKSDSGVALTFSCPKRTVNRESLFQRLQTNPG LTLTQMAREMRESQGLQVRRGSTQMVAYPFGQQGR-SQNRRAT--NTNRRRPASRTQPRQ >NP_081094.2 cartilage intermediate layer protein 2 precursor [Mus musculus] ---------------------------------------------------------MAS PLPLLY--LCLAALHLAGARDATPTEEHTSTARGLQGRPPDTGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPAAMGERVHA NPERGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EAAWGAWGAWGLCSKSCGL-GRRLRRRSC --QSSSGDTCPGSP-QEAQKCVRSRCP----------------GC-----------SSDT CGCPNHILLGSVVTPSGRPLSGARVSLRT---RP-GTIATSGTHGTFQVPGVCAGSK-AS VSAQMNGFSAGTAQAHANSSNTATVTIILEELGKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRQQGSG-PHLELQGLHQAQAGEYHCKAWNEAGTVR----SRA ALLTILAPGQQACDPRPQEHLIKLPDDCGQPGG------GPTYLDVGLCADTRCPGPVGS -GPRCGDAGS--RCCSVLRLESRDIRCSGYVLPVKVVAECGCRKCLPRRGLVRGRVVAAD S-GEPLRFARILLGRAPIGFTSYQGDFTIEVPPATERLVVTFVDPSGDFVDSVRVLPFDP RGAGVYHEIRALRKAAAVLLDAERGGEIPLGSTEEAPALGELVLPPGTFHHPDGRPYTGP VEARVTFVDPRDLASASAASSDLRFLDSAGELAPLRTYGMFAVDLRAPGSTEQLHVARAD VHVDADHVRMPGHAEALALWSLDPETGLWEEEGSEQGSGGFRRE--------TAAARVRR EE-RAFLVGALTMRERRLFNLDVPERRRCFVKVRAYGTDRFAPAEQVQGVVVTLLNLEPA PGFTANPRAWGRFDSAVTGPNGACVPAFCDAEKPDAYTAFVTAAL-GGEELEAAPSRPRA TAAVVGVAQPYLERLGYQRTDHDDPALKRTGFRLNLARPRAGHESEAHGPVYPWRRLRDC EDAPVTDSHFRFSRVEADKYEYDVVPFHEGAPASWTGDLLAWWPNPQEFRACFLKVRLQG PQEYMVRSHNAGGTHEATRGRLYGLRDTRSVRHPERP----GASAACVEFKCGGMLFDQR QVDRTLVTVTPQGSCRRVAVNTLLQDYLARHPPLAAADDPAAFAMLAPLDALGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPA-RPSLFQRLLENPS SALGDIRREMGQATR------------YSRVNQTQ-AGDTGPF--------GPGQ----- >NP_001100777.1 cartilage intermediate layer protein 2 precursor [Rattus norvegicus] ---------------------------------------------------------MSS PLPLLY--LCIAAAHLAGARDATPTEEHTATVRGLQGRPPDPGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPAAIGERVHA NPERGFWCLNREQPRGRRCSNYHVRFRCPLDPPYLP------PCSA-------------- -------------------------------EAAWGAWGAWGLCSKSCGP-GRRLRRRSC --QSSSGDTCPGSP-QEAQKCVRSRCPAPPKSSLCPCCSHVPLGC-----------SSDT CGCPNHILLGSVVTPSGRPLSGARVSLRT---RP-GTVATSDTHGTFRVPGVCAGSK-AN VSARMNGFSTGTAQAHANTSNSAVVTIVLEELGKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRQQGSG-PHLELQGLREEQAGEYHCKAWNEAGTVR----SRA AHLTVLAPGQPACDPRPQEHLIKLPDDCGQPGG------GPTYLDVGLCADTRCPGPVGS -GPRCGDAGS--RCCSVLRLESRDIRCSGYVLPVKVVAECGCRKCLPRRGLVRGRVVAAD S-GEPLRFARILLGLAPIGFTSYQGDFTIEVPPATERLVVTFVDSSGEFVDSIRVLPFDP RGAGVYHEIRVLRKAAAVLLDAEQGGEIPLGGTEEAPALGELVFPPRTFHHPDGRPYSGP VEARVTFVDPRDLASAAAASSDLRYLDSSGELAPLRTYGMFAVDLHAPGSTEQLHVARAD VRVDADHVRMPGHADALALWSLDPETGLWEEEGAEQGGGGFRRE--------KEAVRVRR EE-RTFLVGALTVRERRLFNLDVPERRRCFVKVRAYGTDRFAPSEQVQGVVVTLLNLEPA PGFTANPRAWGRFDSAVTGPNGACVPAFCDAERPDAYTAFVTASL-GGEELEAAPSRPRA TAATVGVAEPYLERLGYQRTDHDDPALKRTGFRLNLARPRTGHESEAHGPVYPWRRLRDC EDAPVTDSHFRFSRVEADKYEYDVVPFHEGAPASWTGDLLAWWPNPQEFRACFLKVRLQG PQEYMVRSHNAGGTHEDTRGHLYGLRDTRSVRNPERP----GASAACVEFKCGGMLFDQR QVDRTLVTVTPQGSCRRVAVNTLLQDYLARHPPLAPADDPATFAMLAPLDALGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPA-RPSLFQRLLENPA SALGDIRREMGQAAR------------DSRVTQTQ-AGDTGPF--------GSGQ----- >XP_015155600.3 cartilage intermediate layer protein 2 [Gallus gallus] ---------------------------------------------------------MER LLLPAL--LALAAFCCSGAAE--SLENDSEPGKSDAPGKPWK-VPSPEELDLN---TAGG GAEWTSWFNIDHPGGDGDYESLDAIRFYY-RGRVCARPVAIQARTTEWELPQDVGEVVHF SPKKGFRCVNKEQPHGKTCSNYHIRFLCPLEHIFWSHWSSWSPCSRSACGSSGTQSRRRR CVNAQAVSALKELKCRGKAVERRPCSTGPCPEPMWTEWGAWGPCSRSCGSTGTRVRRRSC --QNARKLLCAGHP-SEVQQCPPTPCP--------------------------------- -ACPEHTLQGAVVSATGAALPGARVYLEG---RPPTLLARSDTRGAFRVPGLCVSIG-AN VSAHRDGFAPGLTSVVSNGSGALVAHIVLQKLEKPYMVLHPTPKVRVAGQEVTFCCKASG TPVPKKYYWYQNGTLLDRTAHRYS-SRLVLRALTPEQAGSYHCKASTEAGAIR----SAP AQLTVLAQGQQSCKAAPEPSLVELPAECHRDAG------ASRYYDVGHCPSTPCAGSPAD -GQRCGAGAR--RCCGVRRMEMREIRCGGSVLPIKVVAKCGCGPCAQPRVLVQGRVTAAD T-GEPLRFGQIFLGKKKIGFTGFQGSFTIEVPPDTQRLVARFVDRQQRLVDAVKVLPFDR RGGAVYQEVKMMRKKEAVELDAGQTNAIPLGEASGREPIAELVIPAGAFLRPSGEVFGGT VKASVTFLDPRDMATARAASSDLSFANADGEIVPLRTYGMFAVDFRDGESGTALQTGPVE VRMDAGQIGMAEHLRKMKLWSLNPETGLWEEE------GVLRP---------TEERRGRR EE-RTFLVGNMEIRERRLFNLDVPEDRRCFVKVRAYSNEKFNPYEQLEGVVISLINLEPQ PGFPANPRAWGRFDSVVTGPNGACLPAFCDARRPDAYTAYITATL-GGEELEAVPSSPKL NPNAVGVSQPYLNKLGYRRLDHDDPDIKKTAFQVNVAKPDPNNIDETNGPIYPYRSLREC EEAPVSANHFRFYRVEVDKYEYNVVPFKESDLTSWTGDYLSWWPNPQEFRACFIKVRIEG PQEYMVRSRNEGGSHPRTVGQLYGLRDARSVRDAMRE----GSSGACLEFKCSGMLYDQS LVDRTLVSVIPQGSCRRTAVNGLLRDYLARHPPVADANNTAAFTMLAPVDPLGHNYGIYT VTDQNPRLAKEIAIGRCFDGTSDGFSREMKSDAGTAVTFTCQERPAGRESFFQRLLTSPA EALDEIRREMGAGEL---RRAPPEVLDFASGVRAL-SPAPPPRTPGSRRRMGRVRAQQ-- >XP_541920.2 cartilage intermediate layer protein 2 isoform X1 [Canis lupus familiaris] ---------------------------------------------------------MAS APPLLC--LLVAAAHLAGARATTTPEEPTATAWGLEGPSLSPGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSTVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EATWGAWGPWGPCSGSCGP-GRRLRRRRC --PSPTGDACPGRP-LEAQKCVRPTCP----------------GC-----------SSKT CKCPNHVLLGSVVTPSGRPLPGARVSLRD---WS-GTVAITDAHGTFRMPGVCANSR-AN VSAQMDGFSAGLGQAQANGSISAVVTVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASG TPVPKKYSWFHNGTLLDRREHRYG-AHLELRGLRPDQAGTYHCKAWNDAGTVR----SGT AWLTVLGPGQPACNPQPQEHLIKLPDDCGQPGS------GPTYLNVGLCPDTLCPSPAGS -SPRCGDAGS--RCCSVRRLESREIHCSNYVLPVKVVAECGCQKCLPPRGLVRGRVVATD S-GEPLRFAQILLGQEPIGFTSYQGDFTIEVPPSTQRLVVTFLDPSGEFMDTVTVLPFDP RGGGVYHDVKAMRKKAPVILDAGESNRIPLGEMQDEAPLGELVLPPGAFRRADGEPYTGA VEARVTFVDPRDLSSAAAAPSDLRFVDSDGELAPLRTYGMFSVDLRAAGSAEQLQAGPVA VRVDAGQIRMAGHVEALRLWSLNPDTGLWEEE------SGFQPER-------SAAARARR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPNEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDEARPDAYTALVTASL-GGEELEPAPSRPRP RAATVGVAQPYLERLAYRRTDHDDPALKRNGFRINLAKPRPGEPAEAKGPVYPWRSLREC QEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDVLAWWPNPQEFRACFLKVQIQG PQEYMVRSHNAGGSHPRTQGQLYGLRDARSVRDPERP----GTTAACVEFKCSGMLFDQR QVDRTLVTIMPQGSCRRVAINGLLRDYLARHPPAAPADDPAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKAEAGTAVTFQCREPPAGRPSLFQRLLESPA TALGDIRREMGQVAR------------------AQ-AQSTGPL----RTRRGRAQQ---- >NP_001179457.1 cartilage intermediate layer protein 2 precursor [Bos taurus] ---------------------------------------------------------MSS LPTLLC--LCVAAAHLAGARGTPDAEEPTVTAWGLEGSSLRPGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EATWGSWGPWGPCSGSCGP-GRRLRRRRC --SSPAGDACPGRP-SEAQKCVRPRCP----------------GC-----------GPST CGCPDHILLGSVVTPSGRPLPGARVSLRD---WP-GTIATSDAHGTFRMPGVCASSQ-AN VSAQMDGFSAGMTQAQANSSMSSVATVVLNKLEKPYLVKHPESQVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRTHRYG-AHLELHGLRPDQAGTYHCKAWNDAGAVR----SGA ARLTVLAPGQPACDPRPREHLIKLPDDCGQPGR------GPTYLDVGLCPDTLCPSPAGS -SPRCGDAGS--RCCSVRRLESRKIHCSGYTLPVKVVAECGCQKCLPLRGLIRGRVVAAD S-REPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDP RGAGVYHEVKAMRKKAPIILDARQSNTISLGEMGEEAPLGELIIPPGAFRRADGQPYTGA VEAQVTFVDPRNLTSAAAAPSDLLFVDGDGELAPLRTYGMFSVDLRAAGSAEQLQTGLVA VRVAADQIRMPGHMEALKLWSLNPDTGLWEEE------SGFQRER-------PASQRARR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATL-GGEELEPAPSRPRP LPAAVGVAQPYLDRLDYRRTDHDDPALKRSGFRINLAKPRPGEPTEANGPVYPWRSLREC QEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRP----SSSAACVEFKCSGMLFDQR QVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPLAPTDDLASFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPS AALGDIRREMGESAR------------------VQ-ARASSPL----RTRRGRAQQ---- >XP_043323422.1 cartilage intermediate layer protein 2 isoform X1 [Cervus canadensis] ---------------------------------------------------------MAS LPTLLY--LCVAAAHLAGARGTPDTEEPTVTAWGLEGSSLRPGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EATWGSWGPWGPCSGSCGP-GRRLRRRRC --PSPAGDACPGRP-SEAQKCVRPRCP----------------GC-----------GPNT CGCPDHILLGSVVTPSGRPLPGARVSLRD---WP-GTIATSDAHGTFRMPGICASSR-AN ISAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRTHRYG-AHLELHGLRPDQAGAYHCKAWNDAGAVR----SGI ARLTVLAPGQPACDPRPREHLIKLPDDCGQPGR------GPTYLDVGLCPDTLCPSPAGS -RPRCGDAGS--RCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAAD S-REPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDP RGAGVYHEIKAMRKKAPIILDASQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGV VEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRTYGMFSVDLRAAGSAEQLQTGLVA VRVATDQIRMPGHLEALKLWSLNPDTGLWEEE------SSFQRER-------PASQRARR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATL-GGEELEPAPSRPRP LPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRSLREC QEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRP----SSSAACVEFKCSGMLFDQR QVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPS AALGDIRREMGDVTR------------------VQ-ARASSPL----RTRRGRAQQ---- >KAB0361517.1 hypothetical protein FD754_005673 [Muntiacus muntjak] ---------------------------------------------------------MAS LPTLLC--LCVAAAHLAGARGTPDTEEPTVTAWGLEGSSLRPGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EATWGSWGPWGPCSGSCGP-GRRLRRRRC --PSPARDACPGRP-SEAQKCVRPRCP----------------GC-----------DPNT CGCPDHILLGSVVTPSGRPLPGARVSLRD---WP-GTIATSDAHGTFRMPGICASSR-AN VSAQMDGFSAGMAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLNRRTHRYG-AHLELHGLRPDQAGAYHCKAWNDAGAVR----SGI ARLTVLAPGQPACDPRPREHLIKLPDDCGQPGR------GPTYLDVGLCPDTLCPSPAGS -RPRCGDAGS--RCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAAD S-REPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDP RGAGVYHEIKAMRKKAPIILDSSQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGA VEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRTYGMFSVDLRAAGSAEQLQTGLVA VRVATDQIRMPGHLEALKLWSLNPDTGLWEEE------SGFQRER-------PSSQRARR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATL-GGEELEPAPSRPRP LPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRSLREC QEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRP----SSSAACVEFKCSGMLFDQR QVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPS AALGDIRREMGDVTR------------------VQ-ARASSPL----RTRRGRAQQ---- >KAB0385514.1 hypothetical protein FD755_000470 [Muntiacus reevesi] ---------------------------------------------------------MAS LPTLLC--LCVAAAHLAGARGTPDTEEPTVTAWGLEGSSLRPGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EATWGSWGPWGPCSGSCGP-GRRLRRRRC --PSPARDACPGRP-SEAQKCVRPRCP----------------GC-----------DPNT CGCPDHILLGSVVTPSGRPLPGARVSLRD---WP-GTIATSDAHGTFRMPGICASSR-AN VSAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRTHRYG-AHLELHGLRPDQAGAYHCKAWNDAGAVR----SGI ARLTVLAPGQPACDPRPREHLIKLPDDCGQPGR------GPTYLDVGLCPDTLCPSPAGS -RPRCGDAGS--RCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAAD S-REPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDP RGAGVYHEIKAMRKKAPIILDSSQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGA VEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRTYGMFYVDLRAAGSTEQLQTGLVA VRVATDQIRMPGHLEALKLWSLNPDTGLWEEE------SSFQRER-------PTSQRARR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATL-GGEELEPAPSRPRP LPAAVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRSLREC QEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRP----SSSAACVEFKCSGMLFDQR QVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPS AALGDIRREMGDVTR------------------VQ-ARASSPL----RTRRGRAQQ---- >OWK11996.1 CILP2 [Cervus elaphus hippelaphus] ---------------------------------------------------------MAS LPTLLY--LCVAAAHLAGAR----------------GSSLRPGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EATWGSWGPWGPCSGSCGP-GRRLRRRRC --PSPAGDACPGRP-SEAQKCVRPRCP----------------GC-----------GPNT CGCPDHILLGSVVTPSGRPLPGARVSFRD---WP-GTIATSDAHGTFRMPGICASSR-AN ISAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRTHRYG-AHLELHGLRPDQAGAYHCKAWNDAGAVR----SGI ARLTVLAPGQPACDPRPREHLIKLPDDCGQPGR------GPTYLDVGLCPDTLCPSPAGS -RPRCGEAGS--RCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAAD S-REPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDP RGAGVYHEIKAMRKKAPIILDASQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGV VEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRTYGMFSVDLRAAGSAEQLQTGLVA VRVATDQIRMPGHLEALKLWSLNPDTGLWEEE------SSFQRER-------PASQWARR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATL-GGEELEPAPSRPRP LPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRSLREC QEAPVTAGHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRP----SSSAACVEFKCSGMLFDQR QVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPS AALGDIRREMGDVTR------------------VQ-ARASSPL----RTRRGRAQQ---- >KAF4014309.1 hypothetical protein G4228_006190 [Cervus hanglu yarkandensis] ---------------------------------------------------------MAS LPTLLY--LCVAAAHLAGAR----------------------ARVVPA-----------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ ------------------------------------------------------------ -------------------------------------------GC-----------GPNT CGCPDHILLGSVVTPSGRPLPGARVSLRD---WP-GTIATSDAHGTFRMPGICASSR-AN ISAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRTHRYG-AHLELHGLRPDQAGAYHCKAWNDAGAVR----SGI ARLTVLAPGQPACDPRPREHLIKLPDDCGQPGR------GPTYLDVGLCPDTLCPSPAGS -RPRCGDAGS--RCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAAD S-REPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDP RGAGVYHEIKAMRKKAPIILDASQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGV VEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRTYGMFSVDLRASGSAEQLQTGLVA VRVATDQIRMPGHLEALKLWSLNPDTGLWEEE------SSFQRER-------PASQRARR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATL-GGEELEPAPSRPRP LPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRSLREC QEAPVTAGHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRP----SSSAACVEFKCSGMLFDQR QVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPS AALGDIRREMGDVTR------------------VQ-ARASSPL----RTRRGRAQQ---- >XP_018112382.1 cartilage intermediate layer protein 2 [Xenopus laevis] ---------------------------------------------------------MPA LLSSLL--IFVFL-------------------------------------KIS---ATTG ASEWTSWFNVDHPEGEGDYETVEAVRFYY-PDRLCSRPIALEARTTEWMAPEDTMEVVHS SPEKGFWCSNKEQKDGNLCSNYHVRFKCPL------------------------------ -------------------------------EDYWSHWEAWTPCTRTCGG-GRRIRRRVC ---TSKKNNCSGRT-YQLQKCGKAPCK----------------ACDLLCANGESNAACRR CNCDSHTLVGKVQSSRGSALHGARVFLKY------ELLGTTDLRGNIRIAGICSDDH-VN VTVVLDGYTSVTLQNVKNGSSSSYFLALLKREEKPYMVQHPYSKIRKEGQKVTFCCEATG NPIPTKYYWYHNSTLLDKQIFKYD-KALTLRNLQAVQTGTYQCRASNGLGVVK----SSV AQLTIVGKQENSCSKSPQEHLIKLPAGCFQTTT------RSLYHNVGKCPNAQCVGSVSS -EILCKDKVD--YCCGVKQMMLQEVQCPGYILPIMVVKECGCVKCIQPKVLVRGRVTAYD T-GEPLRFGQIFVSGENMGFTGYKGEFTLEVPAGTKRLVVTFIDREDKFVETIKVFPFDP KGSTVYQDVKIMRKSQPKNLDPGIINIIPLGTVEAEDPMAEIVIPPYSFTRTSGEVYNGT VKASVTFLDPRNISTASAASSDLNFVNRDGEIAPLRTYGMFAVDFRQEDTNAILLAGKVE VHLNTEQVKMPQHLKEMKLWSLNEETGMWEEE------SRFQVV--------KGGQRKRR EE-RSFLIGQLEIRERRLFNLDVPEHRRCFVKVRAYMNEKFIPSEQLEGVVINLINLEPV AGFSSNPRAWGRFDSVITGKNGACLPAFCDAQRPDAYTAYVTAIM-GGEELEAAPSSPKL NPNVVGVSQPYLSKLGYQRSDHEDTAGKKTAFKLNLAKPNPNNLDETSGPIYAYRNLRGC EGAPVSDNHFRFYRVEEDKYEFNVVPFVETDLTSWIGGYLSWWPNPQEFRACYIKIRIQG TQEYMIRSRNAGGSHPRTTGQLYGLRDIRSVRDLHVD----RSSAACVEFKCSGMLYDQS VVDRTHVVINPQGSCRIIEINRLLKEYLARHPPVVLGNDTGTFNMLAPVDPLGHNYGIYT VTDQNPKLAKEIAIGRCFDGTSDGFSREMKSTAGVALTFRCQEKPVTHESFFQRLLNNPG ETLREIRRGMLENEQ---NENLPQVVPYPATGRTT-SRTRRPI--ANQRRPGQVRRN--- >XP_008267106.1 PREDICTED: LOW QUALITY PROTEIN: cartilage intermediate layer protein 1 [Oryctolagus cuniculus] ---------------------------------------------------------MAG TKAWVCSFLVLEVASVLGRRPML-----TQSVRRVQPGKRTPSILAKPADPSE------S PGEWTTWFNIDHPGGLGDYERLDAIRFYY-GDRVCARPLRLEARTTNWMPAGSNGQVVHG SPHEGFWCLNREQRPGQNCSNYTVRFLCPPGSL-----------------------RQDS -------------------------------ERIWSPWSRWSKCSAACGHTGVQTRTRTC --LAESMALCTEAT-EEGRLCETQACT----------------ACDLSCPMGKANADCDA CMCQDFLLHGAVSLPGGAPAAGATVYLLN---KTPKLLTQTDSNGRFRVPGLCPDGT-TI LKIMKTKFAPIVLTMPKTRLNVATVNAEFRRAETPYMLTSPQTKARRAGQSVSLCCKATG KPSPDKYLWYHNNTLLHPSLYKHE-SKLVLRNLRQEQAGEYFCKAQSDAGAVK----SQV AQLMVIAPDETPCNPVPESYLIRLPHDCFQNAT------NSFYYDVGRCPVKTCAGQQDN -GLRCQDAE---NCCGISKMKEKEIQCSGYTLPTKVAVQCSCQRCTETRSIVRGRVSAAD T-GEPMRFGHVYMGNSRVSMTGYKGTFTLHVPQDTERLVLTFVDRLQKFVNTTKVLPFNK KGSAVFHEIKMLRRKEPITLEALETNIIPLGEVDGEDPVAELEIPPKSFFRQNGEPYTGK VKASVTFLDPRNVSTATAAQSDLNFVNDEGDTLPLRTYGMFSLDFTDEATAEPLNAGKVK VHLDSTQVKMPEHVAAMKLWSLNPDTGLWEEE------GDFKL---------ESRRRNKR EQ-RTFLVGNMEIRERRLFNLDVPESRRCFLKVRAYRSERFLPSEQIQGVVVSAINLEPR AGFSSNPRAWGRFDSVITGPNGACVPAFCDDQSPDAYSAYVLASL-AGEELEAVESSPKF NPNAIGVPQPYLNKLKYRRTDHEDPQVKKTAFQISMAKPRPNSAEESNGPIYAFENLRAC EDAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIVG AVEVNVRSRNMGGTHRRTVGKLYGIRDVKSTRDRDQP----NVSSACLEFKCSGMLYDQD RVDRTLVKVIPQGSCQRASVNSMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYT VTDQDPRTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCAERQVGRQSAFQYLQSTPA RTPAA-----GTGQG---RVPPRR------QQRARRGGQRQPERPASLRFSGAAQQPPSN >XP_009251325.1 cartilage intermediate layer protein 2 isoform X1 [Pongo abelii] ---------------------------------------------------------MAS LLPLLC--LCVVAAHLAGARDATPTEEPMATALGLERRSVYPGQPSPALEDWEARAVPAE ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EASWGAWGPWGPCSGSCGP-GRRLRRRHC --PSPAGDACPGRP-LEAQKCLRPRCP----------------GC-----------SLDT CECPDHILLGSVVTPSGQPLPGARVSLRD---QP-GTVATSDAHGTFRVPGVCADSR-AN IRAQMDGFSAGEAQAQANGSIS-VVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRAHGYG-AHLELRGLRPDQAGIYHCKAWNEAGAVR----SGA ARLTVLAPGQPACDPRPREYLIKLPEDCGQPDS------GPAYLDVGLCPDTRCPSLAGS -GPRCGDASS--RCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAAD S-GEPLRFARILLGQEPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDP RGAGVYHEVKAMRKKAPVILDASQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGP VEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVA VRVAASQIHMPGHVEALKLWSLNPETGLWEEE------SGFRREG-------SSGPRVRR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATL-GGEELEPAPSLPRP LPATVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLREC QGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERP----GTSAACVEFKCSGMLFDQR QVDRTLVTIMPQGSCRRVAVNGLLRDYLTRHPPPVPAEDPAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPA TALGDIRREMSEVAQ------------------AQ-ARASGPL----RTRRGRVRQ---- >XP_003123618.1 cartilage intermediate layer protein 2 isoform X1 [Sus scrofa] ---------------------------------------------------------MAS LPTLLC--LCVAAAHLAGARGTTTPEEPTATAWDLEGPSLRPGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EATWGAWGPWGPCSGSCGP-GRRLRRRRC --PSSAGDACPGRP-LEAQKCIRSPCP----------------GC-----------SLNI CGCPDHILLGSVVTPTGRPLPGARVSLRD---WP-GTVATSNAHGTFRMPGVCASSR-VN VSAQMDGFSAGMAQAQANSSISAVVTVVLKKLEKPYLVKQPESRVREAGQNVTFCCKASG TPIPKKYSWFHNGTLLDRRTHRYG-AHLELHGLHPDQAGTYHCKAWNDAGAVR----SGT ARLTVLAPGQPACDPQPREHLIKLPDDCSQPGS------GPTYLDVGLCPDTLCPSATGS -SPRCGDAGS--RCCSVRRLESRKIRCSGYNLPVKIVAECGCQKCLPRRGLIRGRVVAAD S-GEPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVITFVDTSGQFVDTVRVLPFDP RGAGVYHEVKAMRKKAPVILDASQSNTIPLGELEDEAPLGELVIPPGAIRRADGEPYVGS VEARVTFVDPRDLTSAAAAPSDLRFVDSDGELAPLRTYGMFSVDLRAPDSTEQLQTGPVA VRVAASQIRMAGHVEALKLWSLNPDTGLWEEE------SGFQRER-------SAAQRVRR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPNEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDTDRPDAYTALVTATL-GGEELEPATSRPRP LPATVGVAQPYLDKLGYRRTDHDDPSLKRNGFRINLAKPRSGDPDEANGPVYPWRNLREC QEAPVTANHFRFARVEADKYEYNVVPFREGVPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNAGGSHPRTQGQLYGLRDARSVRDPERP----SMSAACVEFKCGGMLFDQR QVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPADDLAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPAAGRPSLFQRLLESPS TALGDIRREMGEVAR------------------AQ-ARASVPL----RTRRGRARQ---- >XP_003817771.2 cartilage intermediate layer protein 2 [Pan paniscus] MGRGQGGICGRIPPPLSVPAAARPAGV---------GPEHAAEPGPSLGRSAP---AMAS LLPLLC--LCVVAAHLAGARDATPTEEPMATALGLERRSVYTGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EASWGAWGPWGPCSGSCGP-GRRLRRRHC --PSPAGDACPGRP-LEAQKCVRPRCP----------------GC-----------SLDT CECPDHILLGSVVTPSGQPLLGARVSLRD---QP-GTVATSDAHGTFRVPGVCADSR-AN IRAQMDGFSAGEAQAQANGSIS-VVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRAHGYG-AHLELRGLRPDQAGIYHCKAWNEAGAVR----SGT ARLTVLAPGQPACDPRPREYLIKLPEDCGQPGS------GPAYLDVGLCPDTRCPSLAGS -SPRCGDASS--RCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAAD S-GEPLRFARILLGQEPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDP RGAGVYHEVKAMRKKAPVILHASQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGP VEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVA VRVAASQIHMPGHVEALKLWSLNPETGLWEEE------SGFRREG-------SSGPRVRR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATL-GGEELEPAPSLPRP LPAAVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLREC QGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERP----GTSAACVEFKCSGMLFDQR QVDRTLVTIMPQGSCRRVAINGLLRDYLTWHPPPVPAEDPAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPA TALGDIRREMSEVAQ------------------AQ-ARASGPL----RTRRGRVRQ---- >XP_003982175.1 cartilage intermediate layer protein 2 [Felis catus] ---------------------------------------------------------MAS LPPLLC--LFVAAAHLAGARVTTPPEEPTATAWGFEGPSLRPGQPSPALEDWE------E ASQWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSTVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EATWGAWGPWGPCSGSCGP-GRRLRRRRC --PSPSGDACPGRP-LEAQKCVRPPCP----------------GC-----------SSKT CTCPDHILLGSVVTPSGRPLPGARVSLRD---WP-GTVAITDAHGTFRIPGVCASSR-AN ISAQMDGFSAGLGQAQANGSISAVVTVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRREHRYG-AHLELRGLRPDQAGTYHCKAWNDAGTVR----SGS ARLTVLAPGQPACNPQPQEHLIKLPDDCGQPGS------GPAYLDVGLCSDTLCPSPAGS -SSRCGDSGS--RCCSVRRLESKEIHCSNYVLPVKVVAECGCQKCLPPRGLVRGRVVATD S-GEPLRFAQILLGREPIGFTSYQGDFTIEVPPSTQRLVVTFVDPSGEFMDTVRVLPFAP RGGGVYHDVKAMRKKAPVILDASQSNTIPLGELEEEDPLGELVLPPGAFRRADGAPYTGA VEARVTFVDPRDLTSAAAAPSDLRFVDSDGELAPLRTYGMFAVDLRAAGSAEQLQAGPVA VRVNAGQIHMEGHVEALKLWSLNPDTGLWEEE------SGFQREG-------SAAPRVRR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPNEQVEGVVVTLVNLEPA PGFAANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATL-GGEELEPAPSRPRP HAATVGVAQPYLDKLGYRRTDHDDPALKRNGFRINLAKPRPGDPAEANGPVYPWRSLREC QEAPVTASHFRFARVEADKYEYNVVPFREGVPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNAGGSHPRTQGQLYGLRDARSVRDPEHP----GTSAACVEFKCSGMLFDQR QVDRTLVTITPQGSCRRVAVNGLLRDYLARHPPAAPADDPAAFAMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPA TALGDIRREMGEVTR------------------AQ-AQAAGPL----RTRRGRARQ---- >XP_027825142.1 cartilage intermediate layer protein 2 [Ovis aries] ---------------------------------------------------------MAS LPTLLW--LCVAAAHLAGARGTPDAEEPTVTAWGLEGSSLRPGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHL NPTRGFWCLNREQPRGRSCSNYHVRFRCPL------------------------------ -------------------------------EATWGSWGPWGPCSGSCGP-GRRLRRRRC --PSPAGDACPGRP-SEAQKCVRPRCP----------------GC-----------GPNT CGCPDHILLGSVVTPSGHPLPGARVSLRD---WP-GTVATSDAHGTFRMPGVCASSR-AN VSAQMDGFSAGMAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRTHRYG-AHLELHGLRPDQAGTYHCKAWNDAGAVR----SGT ARLTVLAPGQPACDPRPQEHLIKLPDDCGQPGR------GPTYLDVGLCPDTLCPSPAGS -SPRCGDAGS--RCCSVSRLESRKVHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAAD S-SEPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDP RGAGVYHEVKAMRKKAPIILDARQSNTISLGEMGEEAPLGELVIPPGAFRSADGQPYTGA VEAQVTFVDPRNLTSAAAAPSDLRFVDADGELAPLRTYGMFSVDLRAAGSAEQLHTGLVA VRVAADQIRMPGHVEALKLWSLNPDTGLWEEE------SGFQRER-------PASRRARR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFSPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTAVVTATL-GGEELEPAPSRPRP LPAAVGVAQPYLDRLAYRRTDHDDPALKRSGFRINLAKPRPGDPSEANGPVYPWRSLREC QEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNLGGTHPQTQGQLYGLRDSRSVRDPQRP----SSSAACVEFKCSGMLFDQR QVDRTLVTVMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPS AALGDIRREMGQASR------------------VQ-ARASGPL----RTRRGRAQQ---- >KYO23576.1 cartilage intermediate layer protein 2 [Alligator mississippiensis] ---------------------------------------------------------MRE SECPTV--------------------------------------------------VSVS GTEWTSWFNIDHPGGDGDYETLEAIRFYY-QGRVCAQPLALEARTTEWELPRDVGEFVHA SPRKGFWCINQEQPEGRTCSNYHVRFLCPL------------------------------ ------------------------------------------------------------ -------------------------------------------ACQLTCAAGKANKDCSG CTCPDHTLLGTVVSAEGSALANARVALQD---RPQATLARTDQRGRFRVPGVCAGSA-AN VTVQLERFSPGAAPVIASGPQTSTVQVTLRRLEKPYMVMHPDSKVRTAGQQVTLCCKASG TPVPRKYYWYHNGTLLDRKVYRYD-GRLVLKELQPRHAGAYHCKASSDAGAIK----SAI ARLTVLGKGQPSCRARPEQSLIRLPGECFPDAS------GSPYYDVGRCPATRCAGSLAE -KRQCRDDKE--RCCGVRRMELREVRCAGYVLPIKVVAECGCETCAQPKVLVQGRVVAAD D-GEPLRFGQVFLGQKSIGFTGYQGAFTIEVPPGTRRLVVRFVDPLQKFLDTVKVLPFDS QGSAVYQDVRVMRKKTPMDLDAAQTNALPLGELAGEGPVGELVFPAGAFRRASGEPYNGT VKASVTFLDPRDAATVATASSDLSFVNAEGDMVPLRTYGMFAVDLRARAGGERLQASGVE VRMDAGQVRMPEHLPKMKLWSLNPTTGLWEEE------GALRP---------APARRGKR EE-RTFLVGNLEIRERRLFNLDVSENRRCFVKVRAYGSEKFSPLEQLQGVVVTLVNLEPR PGYPANPRAWGRFDSAVTGRNGACLPAFCDGQRADAYTAYVTATL-GGEELEAAASRPSP DPSTVGVSQPYLSKLGYRRLDHTDPRAKKTAFRVNLAKPNPNNVDEVNGPLYPYRSLREC EEAPVSANHFRFSRAEVDKYEYNVVPFEEGDLTSWTRDYLAWWPNPQEFRACYIKVKVEG PQEYMVRSRNVGGSHPWTQGQLYGLRDARSVKDPELE----HSSAACVEFKAAA------ ------TARPPTASCGST------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ >XP_018871353.1 cartilage intermediate layer protein 2 isoform X1 [Gorilla gorilla gorilla] ---------------------------------------------------------MAS LLPLLC--LCVVAAHLAGARDATPTEEPMATALGLERRSVYPGQPSPALEDWEARAVPAE ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EASWGAWGPWGPCSGSCGP-GRRLRRRHC --PSPAGDACPGRP-LEAQKCVRPRCP----------------GC-----------SLDT CECPRHILLGSVVTPSGQPLLGARVSLRD---QP-GTVATSDAHGTFRVPGVCADSR-AN IRAQMDGFSAGEAQAQANGSIS-VVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRQAHGYG-AHLELRGLRPDQAGIYHCKAWNEAGAVR----SGT ARLTVLAPGQPACDPRPREYLIKLPEDCGQPGS------GPAYLDVGLCPDTRCPSLAGS -SPRCGDASS--RCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRIVAAD S-GEPLRFARILLGREPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDP RGAGVYHEVKAMRKKAPVILHASQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGP VEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVA VRVAASQIHMPGHVEALKLWSLNPETGLWEEE------SGFRREG-------SSGPRVRR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSVNPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATL-GGEELEPAPSLPRP LPATVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLREC QGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERP----GTSAACVEFKCSGMLFDQR QVDRTLVTIMPQGSCRRVAVNGLLRDYLTRHPPLVPAEDPAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPA TALGDIRREMSEVAQ------------------AQ-ARASGPL----RTRRGRVRQ---- >XP_011471792.1 cartilage intermediate layer protein 2 [Oryzias latipes] MRRSS----SKTRPSASLLSVDFKLDIRKLRKKLFNHPEICINAVENLSKEISFVRTMLE LNKLRL--LLSLLAYVTLGQG---------SLRTRNISDRSKRTASNRFSDTQ----RTG VTEWTSWFNIDHPGGNGDYERLEAIRFYY-RERVCSRPTAIEARTSDWLTAADTGEVVHS SLEKGFWCINKEQPKGNICSNYHVRFQCPPVQSYWTEWSEWGPCSATVCSDVGIQVRQRK CLSSQPMPLLFVPACQGHHSERRECSTPQC-TAKWSPWGHWGMCSVTCGG-GQRTRRRTC V-RTSVSVQCAGRS-VDIQKCGKTPCPA---------------KCQLVCEEGHPSEDCSL CVCEDHVLHGDVHSVTGVPVEGARVSLAS---HSKALHAQTNAKGQFVLAGVCSSTS-SS IIIKKEKYVPTIVSTSSNTTGLSRLKAVLRSAEKPYVVKHPEDKVRYEGGRVLLCCSATG SPAPSKYYWYHNGTLLDRKIYKYE-EDLMLQDLKFEHSGEYYCKTSNPAGSIK----SSV AILSVIAKGTPACDSTPEAHLIRLPLDCVQPGT------QSKYYNAGRCPHNKCAGSLEF -DMRCKDGAG--FCCGVQSMESRVIDCGSYSLPIRAVTKCICQKCMQPTVIVRGRVVTAD N-NEPLRFGHIYIGKERVGTTGYQGGFTLKIAQDTQRLVVNFVDPTETFLNTPKVFIFDK KSGSIYHDVKVMRKQKPIDINSRETNVIDLGEIKGEDPIGQLVIPPNSFHKDTGEVYEGT VKASVTFIDPRNITTAAATPGDLNFVDDEGDMLPLRTYGMFSVDFRDNSSNKVLGAGAVQ VLLDTQHVKMQEHIPQMKLWSLNPDTGVWEEE------SKFSYST----TTADGHGRSKR EE-RTFLIGNMEIRERRLFNLDVPESRRCYVKVRAYMSDKFLPTEQLEGVVITLINLEPK PGYSSNPRAWGRFDSVITGPNGACLPAFCDAMRPDAYTAYVTAML-NGEELEAAPSTPKM NPNIIGVSKPFLDKLDYQRSDHTDSALKKTAFKINLAKPNQNNLDETNGPIYPYQSMIAC ENAPIDANHFRFFRVEKDKYEYNVVPFEENDLTSWTGDYLSWWPNPQEFRACFIKVRIHG QKEVMVRSRNHGGTHPETKDKLYGIRDIRSTRDMREA----NTSAACVEFKCSGMLYDQS EVDRSLISVLPQGNCRRININNLLQEYLIKHPPFTQSNGSHSFTMMAPVDPLGHNYGIYT VTDQNPRVAKEIAIGRCFDGTSDGFSREMKSDSGVALTFSCPERKINRQSLFQRLQTNPG QTLSQMARDMRDFQGEQRQRSATQVV-FPSEQRGR-TQSRRMS--SGARRTVPVREQQYQ >XP_005505580.2 LOW QUALITY PROTEIN: cartilage intermediate layer protein 2 [Columba livia] ------------------------------------------------------------ ------------------------MENDSEPGKSDGGRKPWKAAPSLAELDLD---TAGR GAEWTSWFNIDHPGGDGDFESLDAI---X-XXXXXXXXXAIQARTTAWELPEEVGEVVHA SPKKGFRCLNKEQPQGKTCSNYHIRFLCP------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------LEKPYMVLHPKAKVRVAGQEVTFCCKASG TPVPKKYYWYHNGTLLDRKVLRYG-SRLVLRGVTPEQTGTYHCKASTEAGVTK----SAP AQLTVLAQGQQSCKPEPEPSLVELPSECPQDAT------GSRYYNVGRCPPTPCPGSPAK -ESGCGGGPG--RCCGVRRMELREIPCAGSLLPVKVVAECGCGPCAQPRVLVQGRVTAAD T-GEPLRFGQIFLGGRKVGFTGYKGSFTIEVPPDTQRLVVRFVDRHQRFIDAIKVLPFDR RGGTVYQEVKMLRKKEPVELDSNQSNVIPLGEARGQEPIGELVLPAGTFLHPSGEVFKGT VKASVTFLDPRDMATASAASSDLSFTNAEGEIVPLRTYGMFAVDFQEGETGAALQTGPVE VRMDAGQVWMPEHLQKMKLWSLNPETGLWEEE------GVL-----------XXXXXXKR EE-RTFLVGNLEIRERRLFNLDVPEDRRCFVKVRAYANEKFNPYEQLEGVVISLINLEPQ PGYPANPRAWGRFDSVVTGPNGACLPAFCDSQRPDAYSAYVTATL-GGEELEAVASSPKL NPNTIGVSQPYLGKLGYRRSDHDDPNLKKTAFQINVAKPDPNNVDETNGPIYPYRSLEEC EEAPVSANHLRFYRVEVDKYEYNVVPFKESDLTSWTGDYLSWWPNPQEFRACFIKVQIEG PQEYMVRSRNLGGTHPRTRGQLFGLRDTRSVRDMLLE----NTSGACVEFKCSGMLFDQS LVDRTLVSIIPQGSCRRTAVNSLLRDYLSRHPPVAENNHTAAFTMLAPVDPLGHNYGIYT VTDQNPRLAKEIAIGRCFDGTSDGFSREMKADTGTAVTFTCQERPAGRQSFFQRLLTAPA QALDEIRREMGAGEM---RRAPPDVMDFASGAQAP-RPSAARRTPSSRQRTGRSRGEP-- >XP_017906987.1 PREDICTED: cartilage intermediate layer protein 2 [Capra hircus] ---------------------------------------------------------MAS LPTLLC--LCVAAAHLAGARGTPDAEEPTVTTWGLEGSSLRPGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHL NPTRGFWCLNREQPRGRSCSNYHVRFRCPL------------------------------ -------------------------------EATWGSWGPWGPCSGSCGP-GRRLRRRRC --PSPAGDACPGRP-SEAQKCVRPRCP----------------GC-----------GPNT CGCPDHILLGSVVTPSGRPLPGARVSLRD---WP-GAVATSDAHGTFRMPGVCASSR-AN ISAQMDGFSAGMAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVRQAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRTHRYG-AHLELRGLRPDQAGTYHCKAWNDAGAVR----SGT ARLTVLAPGQLACDPRPQEHLIKLPDDCGQPGR------GPTYLDVGLCPDTLCPGPAGS -SPRCGDTGS--RCCSVRRLESRKIHCSGYTLPVKVVAECGCQKCLPLRGLIRGRVVAAD S-SEPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDP RGAGVYHEVKAMRKKAPIILDARQSNTISLGEMGEEAPLGELVIPPGAFRRADGQPYTGA VEAQVTFVDPRNLTSAAAAPSDLRFVDADGELAPLRTYGMFSVDLRAAGSAEQLHTGLVA VRVAADQIRMPGHVEALKLWSLNPDTGLWEEE------SGFQRER-------AASRRARR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTAVVTATL-GGEELEPAPSRPRP LPAAVGVAQPYLDRLAYRRTDHDDPALKRSGFRINLAKPRPGDPTEANGPVYPWRSLREC QEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNLGGTHPRTQGQLYGLRDSRSVRDPQRP----SSSAACVEFKCSGMLFDQR QVDRTLVTVMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPAAGRPSLFQRLLESPS AALGDIRREMGQASR------------------VQ-ARASGPL----RTRRGRAQQ---- >XP_025052336.1 cartilage intermediate layer protein 2 [Alligator sinensis] ---------------------------------------------------------MGA LAPAL---LFLAALHCAGARAE-PEENDSRLAKTKPPGKRRKKVPNGTSPDVD-----TA GTEWTSWFNIDHPGGDGDYETLEAIRFYY-QGRVCAQPLALEARTTEWELPRDVGEFVHA SPRKGFWCVNQEQPEGRTCSNYHVRFLCPL------------------------------ -------------------------------EATWGPWGAWSPCSKTCGSGGRRLRRRSC --KKSRTSRCAGRP-SEVQKCARTPCP----------------ACQLTCATGKANKDCSG CTCPDHTLLGTVVSAEGSALANARVTLQD---RPQATLARTDQRGRFRVPGMCAGST-AN VTVQLERFSPGAAPVIASGPRMSTVQVTLRRLEKPYMVMHPDSKVRTAGQQVTLCCKASG TPVPRKYYWYHNGTLLDRKVYRYD-GRLVLKELQPRHAGAYHCKASSDAGAIK----SAI ARLTVLGKGQPSCRARPEQSLIRLPGECFPDAS------SSPYYDVGRCPATRCAGSPAE -ERQCRDDEE--RCCGVRRMELREVRCAGYVLPVKVVAECGCD----------------- ---------QVFLGQKSIGFTGYQGAFTIEVPPDTRRLVVRFVDPLQKFLDTVKVLPFDS QGRAVYQDVP-------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------ELEAAASRPSP DPSTVGVSQPYLSKLGYRRLDHTDPRAKKTAFRVNLAKPNPNNVDEVNGPLYPYRSLREC EEAPVSANHFRFSRAEVDKYEYNVVPFEEGDLTSWTRDYLAWWPNPQEFRACYIKVKVEG PQEYMVRSRNVGGSHPWTQGQLYGLRDARSVKDPELE----HSSAACVEFKCSGMLFDHS GMDRTLVSIVPQGSCYRTATNSLLREYLGRHPPAAPNNDTRAFHMLAPVDPLGHNYGIYT VTDQNPRLAKEIALGRCFHGTSDGFSREMKSEVGTAVTFLCQERPAGRQSLFQRLLEAPA EDLTEIRQEMGRSGQP-------------------------------------------- >XP_015827098.1 PREDICTED: cartilage intermediate layer protein 2 [Nothobranchius furzeri] MH---------------------------------------------------FLK-MLE LTKLAL--LLSFLTSVALGQG---------SVRSRMLSDRSKRTTFQAFSDPQ----TTG VTEWTSWFNIDHPGGNGDYERLEAIRFYY-RERVCVRPTAMEARTTDWVAAADTGEVVHS SLEKGFWCINKEQPLGRACSNYHVRFQCPPVQSYWTDWSEWGPCSTTACNDVGIQLRQRK CVSAQPMPLLFVPACQGHHSERRECTTPPC-TAKWSPWGPWGMCSVTCGG-GRRTRRRTC E-RTSATIQCKGRP-VEVHKCGKSPCPA---------------NCQLVCSEGRPSEDCSS CVCEGHMLQGDVQGVAGFPIAGAAVGLAS---LPQVIRARTDAKGQFRLPGVCSSSS-ML LTIRKEKFVPINVSTSSNTTGLSWLRAVLKSAEKPYIVKHPEDKVRYEGGRLLMCCTATG SPAPDKYYWYHNGTLLDRRVYKYE-EDLVLRDLKLEQSGEYYCKASSPAGSIK----SAP ALLTVVGKGTPACNSTPEFHLIRLPMDCIQLGT------DSKYYNAGRCPHNQCAGSLDY -DMRCRDGAG--FCCGVQKMESRIIDCGNYKLPIRAVSHCGCQKCMQPTVLVRGRVVTAD N-GEPLRFGHIYIGKERVGTTGYQGGFTLQITPDTQRLVVNFVDPTQRFLDTPKVFILDK KGGSIYHDVKVMRKQTPIDIDAGETNFIDLGEIKGEDPIGQLVIPPNSFHKDNGETYEGT VKASVTFIDPRNITTAAAAPGDLNFVDDEGDMLPLRTYGMFSVDFRDESNKEVLGAGAVQ VLLDTQHVKMQEHIPEMKLWSLNPDTGVWEEE------SDFSYST----TTAGGHGRSKR EE-RTFLIGNMEIRERRLFNLDVPESRRCYVKVRAYMSDKFLPTEQLEGVVISLINLEPK PGYSSNPRAWGRFDSVLSGSNGACLPAFCDAMRPDAYTAYVTAML-GGEELEAAPSSPKM NPNIIGVSQPYLDKINYQRSDHDDPALKKTAFKINLAKPNQNNFDETNGPIYPYQNLLGC ENAPVDANHFRFFRVEKDKYEYNVVPFEETDLTTWTRDYLSWWPNPQEFRACFIKIKIHG QKEVMVRSRNLGGTHRETRGKLYGIRDIRSTRDMREA----NTSAACLEFKCSGMLFDQA EVDRSIISVLPQGNCRRISINGLLQEYLIKHPPVAQNNESHAFTMLAPVDPLGHNYGIYT VTDQNPRVAKEIAIGRCFDGTSDGFSREMKSDYGVAVTFSCPEKKINRESLFQRLQTNPG QTLAQMARDMRELEGMQVQRSSTQVVAFPSEQQGR-TQSRRVS--STARRRASIRAQQRQ >XP_016792564.1 cartilage intermediate layer protein 2 [Pan troglodytes] MGRGQGGICGRIPPPLSVPAAARPAGV---------GPEHAAEPGPSLGRSAP---AMAS LLPLLC--LCVVAAHLAGARDATPTEEPMATALGLERRSVYTGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EASWGAWGPWGPCSGSCGP-GRRLRRRHC --PSPAGDACPGRP-LEAQKCVRPRCP----------------GC-----------SLDT CECPDHILLGSVVTPSGQPLLGARVSLRD---QP-GTVATSDAHGTFRVPGVCADSR-AN IRAQMDGFSAGEAQAQANGSIS-VVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRAHGYG-AHLELRGLRPDQAGIYHCKAWNEAGAVR----SGT ARLTVLAPGQPACDPRPREYLIKLPEDCGQPGS------GPAYLDVGLCPDTRCPSLAGS -SPRCGDASS--RCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAAD S-GEPLRFARILLGQEPIGFTAYQGDFTIEVLPSTQRLVVTFVDPSGEFMDAVRVLPFDP RGAGVYHEVKAMRKKAPVILHASQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGP VEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVA VRVAASQIHMPGHVEALKLWSLNPETGLWEEE------SGFRREG-------SSGPRVRR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATL-GGEELEPAPSLPRP LPATVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLREC QGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERP----GTSAACVEFKCSGMLFDQR QVDRTLVTIMPQGSCRRVAINGLLRDYLTRHPPPVPAEDPAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPA TALGDIRREMSEVAQ------------------AQ-ARASGPL----RTRRGRVRQ---- >XP_020766171.1 cartilage intermediate layer protein 2 [Odocoileus virginianus texanus] ---------------------------------------------------------MAS LPTLLC--LCVAAAHLAGARGTPDTEEPTVAAWGLEGSSLRPGQPSPALEDWE------E ASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHL NPTRGFWCLNREQPRGRRCSNYHVRFRCPL------------------------------ -------------------------------EATWGSWGPWGPCSGSCGP-GRRLRRRRC --PSPAGDACPGRP-SEAQKCVRPRCP----------------GC-----------GPNT CGCPDHILLGSVVTPSGRPLPGARVSLRD---WP-GTIATSDAHGTFRMPGICASSR-AN VSAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASG TPMPKKYSWFHNGTLLDRRTHRYG-AHLELHGLRPDQAGAYHCKAWNDAGAVR----SGT ARLTVLAPGQPACDPRPREHLIKLPDDCGQPGR------GPTYLDVGLCPDTLCPSPAGS -RPRCGDAGS--RCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAAD S-REPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDP RGAGVYHEIKAMRKKAPIILDASQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGA VEAQVTFVDPRNLTSVAAAPSDLRFVDRDGELAPLRTYGMFSVELRAAGSAEQLQTGLVA VRVATDQIRMPGHLEALKLWSLNPDTGLWEEE------GGFQRER-------PASQRARR EE-RVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPA PGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATL-GGEELEPAPSRPRP LPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRNLREC QEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQG PQEYMVRSHNVGGSHPRTQGQLYGLRDSRSVRDPQHP----SSSAACVEFKCSGMLFDQR QVDRTLVTVTPQGSCRRVAVNGLLQDYLARHPPSAPAEGLAAFSMLAPLDPLGHNYGVYT VTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPS AALGDIRREMGDVAR------------------VQ-ARASSPL----RTRRGRAQQ---- >XP_030289610.1 cartilage intermediate layer protein 1-like [Sparus aurata] ---------------------------------------------------------MLG LNKVAL--LLSFMASLALGQG---------SVRTRRQLDRSRRVALNTFTDTQ----TTG VTEWTSWFNIDHPGGNGDYERLEAIRFYY-RERVCVRPMAMEARTTDWVAAADTGEVVHS SLEKGFWCINKEQPHGRICSNYHVRFQCPPVQSYWTDWSEWGPCSTTDCDDVGIQVRQRK CVNTQPMPLLLVPACQGHHSERRECSTALC-TAKWSPWGRWGTCSVTCGG-GRRIRRRTC V-RTSLTIQCTGRP-VEVQKCGKSPCPA---------------KCQRVCTEGRPSEDCSR CVCDSHVLQGEVLTVTGVPVAGALVALAS---QPKAIRARTDAKGQFGLKGICSSSS-TL ISIRKEKYAPVTVSTSSNTTGLSWVQALLKSAEKPYIVKHPEDKVRYEGGRVLLCCKATG SPAPDKYYWYHNGTLLDRKVYKYE-EDLVLRDLKPEQSGQYYCKTSSPAGSIK----SSP SLLTVIAKGTPACNSTPETHLIRLPMDCVQPGT------VSKYYNAGRCLLNKCAGSLDF -DMRCRDGSA--FCCGVQNMESRIIDCGSYSLPIRAVTQCGCQKCVQPTVLVRGRVVTAD N-NEPLRFGHIYIGKERVGTTGYQGGFTLQISPDTQRLVVHFVDPTQKFLDTPKVFILDK KGGSIYHDVKVMRKQMPIDINAGEINSINLGEIKGEDPIGQLVIPPNSFHKDNGEIYEGT VKASVTFIDPRNITTAAAAPGDLNFVDDEGDMLPLRTYGMFSVDFRDETNKEVLGAGAVQ VLLDTQHVKMQEHIPKMKLWSLNPDTGVWEEE------SDF-YAT----QTTGGHGRSKR EE-RTFLIGNMEIRERRLFNLDVPENRRCYVKVRAYMSDKFLPTEQLEGVVISLINLEPK PGYSSNPRAWGRFDSVITGPNGACLPAFCDAQRPDAYTAYVTAMM-GGEELEAAPSSPKM NPNIIGVSQPYLDKIDYQRSDHEDPALKKTAFRINLAKPNQNNLDETNGPIYPYQNLIAC ENAPIDANHFRFFRVEKDKYEYNVVPFEENDLTTWTGDYLSWWPNPQEFRACFIKVKIQG QKEVMIRSRNLGGTHRETKAKLYGIRDIRSTRDMREA----NTSAACVEFKCSGMLFDQA EVDRSLISVLPQGNCRRINTNSLLQEYLIKHPPVAQNNESHAFTMLAPVDPLGHNYGIYT VTDQNPRVAKEIAIGRCFDGTSDGFSREMKSDSGVALTFSCPERKINRESLFQRLQTNPG QTLSQMARDMRESEGLQAQRLSSQVVAYPSEQQGR-SQSRRVS--STTRRRVSTRIQRRQ >XP_040176473.1 cartilage intermediate layer protein 2 isoform X1 [Rana temporaria] ---------------------------------------------------------MLA CHFALL--LSVLF---------------------------------------T---SALG ATDWTSWFNVDHPGDDGDFETIEAIRFYY-PHRLCLRPVAIEARTTEWATPKDTKEVVHT DPEKGFWCINKEQKKGYNCSNYHVRFQCPLDLLYWSHWTPWSTCSPTSCGGMGIQIRRRS CITVQPAVTLSLEKCLGEATERRVCVSSSC-VGRWSSWGAWTPCTKTCGG-GKSVRRRIC ---SSKTAPCSGRT-FQIQKCGRTLCR-------------------------ETSELCPG CHCNNHTLLGKIQSIHGFVLHNAKVFMNK------KILGVTDQHGLFMLKGVCMDTP-SN ITIKMDGFSSVTLQSMRKEPKVSYFEAALKKLEKPYMVQNPYSKIRRIGHKVTMCCEATG NPVPTKYYWYHNGTLLDKHTLKYD-KSLTLRNIQATHGGIYQCKASNGVGVIR----SSV AHLNVISKSESLCNKSPNEHLIKLPMDCFQNKT------GSYYYNVGRCPNTQCMDHLSS -NLQCKDEIN--YCCGVKQMKLQEVKCPGYILPVMVVVQCGCAECSRYKIMVRGRVTAYD T-GEPLRFGQIFLSGENKGFTGYKGDFTLEVPEGTKRLVVTFVDRQEKFVETTKVIPFDP KGNTVYQDVKVMRKKDPTDLNPRVTNIISLGDLLGEDPIGEIIIPPNSFRRTSGEPYNST VKASLTFLDPRNISSASAASSDLNFVSRDGDISPLRTYGMFHLDFREDSTNSLLQTGKVE VRLDVEQIKMPQHVKEMKLWSLNPQTGLWEEE------SHFRLP--------SGDKRKKR EE-RSFLIGQLEIRERRLFNLDVPEFRRCFVKVRTFMNEKFMVNEQLEGIVVTLINLEPM PGFSSNPRAWGRFDSVVTGSNGACLPAFCDAVKPDAYSAYVTATM-GGEELEAAPSSPKR NPNVIGVTQPYLSKLNYQRTDHDDSAGKKTAFKINLAKPNPNSLAENRGPIYAYRNLQGC EEASILDNHFRFFRAEEDKYEYNVVPFDETDLTSWIGSYLSWWPNPQEFRACYIKIGIQG PQEYMVRTRNIGGTHTHTVGQLYGLRDTRSVRDLEVE----SSSAACLEFKCSGMLFDQD LVDRTLVTVTPQGSCHVTKINRLLEEYLSRHPPLALGNNTETFNMLAPVDPLGHNYGIYT VTDQNPRLAKEIAIGRCFDGTSDGLSREMKSQVGIAVTFRCQEKPITRKSLFHRLLNNPG ETLSEIRQNMQENEQ---RGTPARVVPYPALQSSSFSQSRKPS--ASQRRPRMAQSG--- >XP_039261724.1 cartilage intermediate layer protein 1-like [Styela clava] ---------------------------------------------------------MQN VIRCKI-FISWAVLAFLG----------------------------------------IA ATQ-------SYVGGNGGYANITSV----------------------------------- ---------------------------VPK------------------------------ -------------------------------FKPWREWSTWSQCDVSCGGVGMQERVRKC RNRQDKSSKCFGREIIESRPCGDAPCG------------------------------TNT VSCDT---VGTVTDSLNIPLEGVEICLGSIKVQKCITITHTNEEGFFSVEGICADSEYAH LLARKNKYVTTRIRLKVNETGRAFATVKLLELVKPTIYYHPESKSRMIGQSVKFCCKARG STKDHLFTWYHNGNVVDANLYSRDPGTLEIRTLRLDDAGEYWCKVSSKTSFAKTTSLSQT AVLSVFESEQNACDEKPGVKLIRLPNDCSMASSRVVQRNNKTYFDVGMCSSVECPAKYAD ISEGCGETMADITCCGPSERKEINLNCRDFVLPIYKTTKCGCQECVKPVIKVRGRAYGND PITDPLRYGYVERSGKRIGRTSYDGGFTVNVPHGSKRLVLTFIDRFGKLMTTTKVVSFKE DGGVTFHDIKMPQKSPEKSFGSQERSVTSLNGVRGQNSVAQIVTAPNGFVRKDGKPYTGK VRASVTFIDPRNETSYQESPTDLAFIDDNGESLPLQTYGMFEMDFRDEDLNE-LNVANAK IVLDQNQMVSTSHARKLKLWSLNLENGMWEEE------ENFKEMEIEDEQVQPGPKRKKR EAPTTFFVGNLEVRERRLYNLDVPVENRCWLKVRAYRSPDFDPNEQVEGVDIVAINMEPK GGFRGNPSAWGRFDSTLTSKYGACVRVFCHEDKPDVYKAIVTATLDSSEELYAAPSGHPV NPKVVGVQGDILRALDYRRSDHSLATGKKTSFQINLPKPRPE--VNYTGPIYPEENYAEC VRAPVTDNHFRFYRTEDFLYEYNTVYMDEHNCITWTPHYLNWWPKPLEYRACYIKVHVSG LST-VIRAKSMGGTHPETRGKLYGIRDDRSVLAQRLEGPFIGDSAACIEFKCSGKLYDME EPDRTLVSVIPQGECQLHRMNGQLSQYLTEHPPAVEGESASEFRMYAPPDPLGHNYGIYT VTDDDPLIAKKTALGRCYAGSSDTTSRIMHARKGVAIYYWCTDRN--------------- ------------------------------------GEIELP------------------
BMGE Cleaned alignment of selected proteins >sp|Q8IUL8|CILP2_HUMAN Cartilage intermediate layer protein 2 OS=Homo sapiens OX=9606 GN=CILP2 PE=2 SV=2 MASLLPLLCLCVVAAHLAGARDATPTEEPMATALGLERRSVYTGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEASWGAWGPWGPCSGSCGPGRRLRRRHCPSPAGDACPGRPLEAQKCVRPRCPSLDTCECPDHILLGSVVTPSGQPLLGARVSLRDGTVATSDAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQANGSIS-VVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRAHGYGAHLELRGLRPDQAGIYHCKAWNEAGAVRSGTARLTVLAPGQPACDPRPREYLIKLPEDCGQPGSGPAYLDVGLCPDTRCPSLAGSSPRCGDASSRCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAADSGEPLRFARILLGQEPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDPRGAGVYHEVKAMRKKAPVILHTSQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGPVEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVAVRVAASQIHMPGHVEALKLWSLNPETGLWEEESGFRREGPRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSLPRPLPATVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERPGTSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLRDYLTRHPPPVPAEDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMSEAAQARASGPLRTRRGRVRQ >tr|F1Q5N7|F1Q5N7_DANRE Cartilage intermediate layer protein 2 OS=Danio rerio OX=7955 GN=cilp2 PE=4 SV=3 MWDFTVVTLVLSTVFVVSLAQG--PIWDSS-RLRRLNQTDRNRKLAYNTLVEPQGVTEWTSWFNIDHPGGNGDYERLEAIRFYY-RERVCSRPVAMEARTTDWVAAADTGEVVHSSLEKGFWCINKEQPFGRSCSNYHVRFQCPPQAMWSQWGSWGACSVTCGKGRRTRRRTCRSSTKIQCTGRPIEVQKCG-NPCPSCSYCICDGQALHGEVFSITGVPVMNATVALASIIRAHTDAKGQFKMDGLCISPQTQIVIRKDKFAPATLPVSNNSTDELWVRAILQSSEKPYIEKHPEDKVRYEGQRATLCCRATGSPKPDKYYWYHNGTLLNRTIFKYDEDLILRDLKPEQSGQYHCKATSLTGSIKSTSAVLTVFTKGTPACKSTPETHLIKLPLDCKQPGTDSKFYNAGRCPHNKCPGALDFDMRCRDGTGFCCGVKEMDAKEINCGRYTLPIKVVSECGCQTCVEPKVLVRGRVVATDNDEPLRFGHIYIGKERIGTTGYQGGFTIQVSPETQRLVVNFVDPSQKFIDTIKVFIFDKRGGAVYHDVKVMRKQEPIDINAAESNTIYLGEMKDEDPIGQLVIPPNSFHKNTGEVYEGTVKASVTFLDPRNITMAAAAPGDLNFVDDEGDMLPLRTYGMFSVDFRDGENQEVLGAGAVQVLLDTEHVKMQEHIPAMKLWSLNPDTGIWEEESNFQPTQGRNKREERTFLIGNMEIRERRLFNLDVPENRRCYVKVRAYMSDKFLPNEQLEGVVINLINLEPKPGYSSNPRAWGRFDSVITGPNGACLPAFCDAQRADAYTAYVTAIMGGEELEAAPSMPKMNPNIIGVSQPYLGKLDYQRSDHEDSALKKTAFRINLAKPNPNNFDETNGPIYPFQSLIACENAPVDANHFRFFRVEKDKYEYNVVPFQESDLTSWTGDYLSWWPNPQEFRACFIKVKIHGATEIMVRSRNLGGTHPQTRGQLYGIRDIRSTRDLHHPNTSAACLEFKCSGMLFDQGSVDRSLISVIPQANCRRIGINSLLQEYLIKHPPVLQNNESHAFNMLAPVDPLGHNYGIYTVTDQNPRVAKEIAIGRCFDGTSDGFSREMKSDSGVALTFSCPKRTVNRESLFQRLQTNPGLTLTQMAREMRESQGSQNRRATNRRRPASRT >NP_081094.2 cartilage intermediate layer protein 2 precursor [Mus musculus] MASPLPLLYLCLAALHLAGARDATPTEEHTSTARGLQGRPPDTGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPAAMGERVHANPERGFWCLNREQPRGRRCSNYHVRFRCPLEAAWGAWGAWGLCSKSCGLGRRLRRRSCQSSSGDTCPGSPQEAQKCVRSRCPSSDTCGCPNHILLGSVVTPSGRPLSGARVSLRTGTIATSGTHGTFQVPGVCAGSKASVSAQMNGFSAGTAQAHANSSNTATVTIILEELGKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRQQGSGPHLELQGLHQAQAGEYHCKAWNEAGTVRSRAALLTILAPGQQACDPRPQEHLIKLPDDCGQPGGGPTYLDVGLCADTRCPGPVGSGPRCGDAGSRCCSVLRLESRDIRCSGYVLPVKVVAECGCRKCLPRRGLVRGRVVAADSGEPLRFARILLGRAPIGFTSYQGDFTIEVPPATERLVVTFVDPSGDFVDSVRVLPFDPRGAGVYHEIRALRKAAAVLLDAERGGEIPLGSTEEAPALGELVLPPGTFHHPDGRPYTGPVEARVTFVDPRDLASASAASSDLRFLDSAGELAPLRTYGMFAVDLRAPGSTEQLHVARADVHVDADHVRMPGHAEALALWSLDPETGLWEEEGGFRRE-ARVRREERAFLVGALTMRERRLFNLDVPERRRCFVKVRAYGTDRFAPAEQVQGVVVTLLNLEPAPGFTANPRAWGRFDSAVTGPNGACVPAFCDAEKPDAYTAFVTAALGGEELEAAPSRPRATAAVVGVAQPYLERLGYQRTDHDDPALKRTGFRLNLARPRAGHESEAHGPVYPWRRLRDCEDAPVTDSHFRFSRVEADKYEYDVVPFHEGAPASWTGDLLAWWPNPQEFRACFLKVRLQGPQEYMVRSHNAGGTHEATRGRLYGLRDTRSVRHPERPGASAACVEFKCGGMLFDQRQVDRTLVTVTPQGSCRRVAVNTLLQDYLARHPPLAAADDPAAFAMLAPLDALGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPA-RPSLFQRLLENPSSALGDIRREMGQATRAGDTGPF----GPGQ- >NP_001100777.1 cartilage intermediate layer protein 2 precursor [Rattus norvegicus] MSSPLPLLYLCIAAAHLAGARDATPTEEHTATVRGLQGRPPDPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPAAIGERVHANPERGFWCLNREQPRGRRCSNYHVRFRCPLEAAWGAWGAWGLCSKSCGPGRRLRRRSCQSSSGDTCPGSPQEAQKCVRSRCPSSDTCGCPNHILLGSVVTPSGRPLSGARVSLRTGTVATSDTHGTFRVPGVCAGSKANVSARMNGFSTGTAQAHANTSNSAVVTIVLEELGKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRQQGSGPHLELQGLREEQAGEYHCKAWNEAGTVRSRAAHLTVLAPGQPACDPRPQEHLIKLPDDCGQPGGGPTYLDVGLCADTRCPGPVGSGPRCGDAGSRCCSVLRLESRDIRCSGYVLPVKVVAECGCRKCLPRRGLVRGRVVAADSGEPLRFARILLGLAPIGFTSYQGDFTIEVPPATERLVVTFVDSSGEFVDSIRVLPFDPRGAGVYHEIRVLRKAAAVLLDAEQGGEIPLGGTEEAPALGELVFPPRTFHHPDGRPYSGPVEARVTFVDPRDLASAAAASSDLRYLDSSGELAPLRTYGMFAVDLHAPGSTEQLHVARADVRVDADHVRMPGHADALALWSLDPETGLWEEEGGFRRE-VRVRREERTFLVGALTVRERRLFNLDVPERRRCFVKVRAYGTDRFAPSEQVQGVVVTLLNLEPAPGFTANPRAWGRFDSAVTGPNGACVPAFCDAERPDAYTAFVTASLGGEELEAAPSRPRATAATVGVAEPYLERLGYQRTDHDDPALKRTGFRLNLARPRTGHESEAHGPVYPWRRLRDCEDAPVTDSHFRFSRVEADKYEYDVVPFHEGAPASWTGDLLAWWPNPQEFRACFLKVRLQGPQEYMVRSHNAGGTHEDTRGHLYGLRDTRSVRNPERPGASAACVEFKCGGMLFDQRQVDRTLVTVTPQGSCRRVAVNTLLQDYLARHPPLAPADDPATFAMLAPLDALGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPA-RPSLFQRLLENPASALGDIRREMGQAARAGDTGPF----GSGQ- >XP_015155600.3 cartilage intermediate layer protein 2 [Gallus gallus] MERLLLPALLALAAFCCSGAAE--SLENDSEPGKSDAPGKPWK-VPSPEELDLNGGAEWTSWFNIDHPGGDGDYESLDAIRFYY-RGRVCARPVAIQARTTEWELPQDVGEVVHFSPKKGFRCVNKEQPHGKTCSNYHIRFLCPLEPMWTEWGAWGPCSRSCGSGTRVRRRSCQNARKLLCAGHPSEVQQCPPTPCP-----ACPEHTLQGAVVSATGAALPGARVYLEGTLLARSDTRGAFRVPGLCVSIGANVSAHRDGFAPGLTSVVSNGSGALVAHIVLQKLEKPYMVLHPTPKVRVAGQEVTFCCKASGTPVPKKYYWYQNGTLLDRTAHRYSSRLVLRALTPEQAGSYHCKASTEAGAIRSAPAQLTVLAQGQQSCKAAPEPSLVELPAECHRDAGASRYYDVGHCPSTPCAGSPADGQRCGAGARRCCGVRRMEMREIRCGGSVLPIKVVAKCGCGPCAQPRVLVQGRVTAADTGEPLRFGQIFLGKKKIGFTGFQGSFTIEVPPDTQRLVARFVDRQQRLVDAVKVLPFDRRGGAVYQEVKMMRKKEAVELDAGQTNAIPLGEASGREPIAELVIPAGAFLRPSGEVFGGTVKASVTFLDPRDMATARAASSDLSFANADGEIVPLRTYGMFAVDFRDGESGTALQTGPVEVRMDAGQIGMAEHLRKMKLWSLNPETGLWEEEGVLRP--RRGRREERTFLVGNMEIRERRLFNLDVPEDRRCFVKVRAYSNEKFNPYEQLEGVVISLINLEPQPGFPANPRAWGRFDSVVTGPNGACLPAFCDARRPDAYTAYITATLGGEELEAVPSSPKLNPNAVGVSQPYLNKLGYRRLDHDDPDIKKTAFQVNVAKPDPNNIDETNGPIYPYRSLRECEEAPVSANHFRFYRVEVDKYEYNVVPFKESDLTSWTGDYLSWWPNPQEFRACFIKVRIEGPQEYMVRSRNEGGSHPRTVGQLYGLRDARSVRDAMREGSSGACLEFKCSGMLYDQSLVDRTLVSVIPQGSCRRTAVNGLLRDYLARHPPVADANNTAAFTMLAPVDPLGHNYGIYTVTDQNPRLAKEIAIGRCFDGTSDGFSREMKSDAGTAVTFTCQERPAGRESFFQRLLTSPAEALDEIRREMGAGELSPAPPPRRRRMGRVRA >XP_541920.2 cartilage intermediate layer protein 2 isoform X1 [Canis lupus familiaris] MASAPPLLCLLVAAAHLAGARATTTPEEPTATAWGLEGPSLSPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSTVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGAWGPWGPCSGSCGPGRRLRRRRCPSPTGDACPGRPLEAQKCVRPTCPSSKTCKCPNHVLLGSVVTPSGRPLPGARVSLRDGTVAITDAHGTFRMPGVCANSRANVSAQMDGFSAGLGQAQANGSISAVVTVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPVPKKYSWFHNGTLLDRREHRYGAHLELRGLRPDQAGTYHCKAWNDAGTVRSGTAWLTVLGPGQPACNPQPQEHLIKLPDDCGQPGSGPTYLNVGLCPDTLCPSPAGSSPRCGDAGSRCCSVRRLESREIHCSNYVLPVKVVAECGCQKCLPPRGLVRGRVVATDSGEPLRFAQILLGQEPIGFTSYQGDFTIEVPPSTQRLVVTFLDPSGEFMDTVTVLPFDPRGGGVYHDVKAMRKKAPVILDAGESNRIPLGEMQDEAPLGELVLPPGAFRRADGEPYTGAVEARVTFVDPRDLSSAAAAPSDLRFVDSDGELAPLRTYGMFSVDLRAAGSAEQLQAGPVAVRVDAGQIRMAGHVEALRLWSLNPDTGLWEEESGFQPERARARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPNEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDEARPDAYTALVTASLGGEELEPAPSRPRPRAATVGVAQPYLERLAYRRTDHDDPALKRNGFRINLAKPRPGEPAEAKGPVYPWRSLRECQEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDVLAWWPNPQEFRACFLKVQIQGPQEYMVRSHNAGGSHPRTQGQLYGLRDARSVRDPERPGTTAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAINGLLRDYLARHPPAAPADDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKAEAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMGQVARAQSTGPLRTRRGRAQQ >NP_001179457.1 cartilage intermediate layer protein 2 precursor [Bos taurus] MSSLPTLLCLCVAAAHLAGARGTPDAEEPTVTAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCSSPAGDACPGRPSEAQKCVRPRCPGPSTCGCPDHILLGSVVTPSGRPLPGARVSLRDGTIATSDAHGTFRMPGVCASSQANVSAQMDGFSAGMTQAQANSSMSSVATVVLNKLEKPYLVKHPESQVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELHGLRPDQAGTYHCKAWNDAGAVRSGAARLTVLAPGQPACDPRPREHLIKLPDDCGQPGRGPTYLDVGLCPDTLCPSPAGSSPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKVVAECGCQKCLPLRGLIRGRVVAADSREPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEVKAMRKKAPIILDARQSNTISLGEMGEEAPLGELIIPPGAFRRADGQPYTGAVEAQVTFVDPRNLTSAAAAPSDLLFVDGDGELAPLRTYGMFSVDLRAAGSAEQLQTGLVAVRVAADQIRMPGHMEALKLWSLNPDTGLWEEESGFQRERQRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATLGGEELEPAPSRPRPLPAAVGVAQPYLDRLDYRRTDHDDPALKRSGFRINLAKPRPGEPTEANGPVYPWRSLRECQEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPLAPTDDLASFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPSAALGDIRREMGESARARASSPLRTRRGRAQQ >XP_043323422.1 cartilage intermediate layer protein 2 isoform X1 [Cervus canadensis] MASLPTLLYLCVAAAHLAGARGTPDTEEPTVTAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCPSPAGDACPGRPSEAQKCVRPRCPGPNTCGCPDHILLGSVVTPSGRPLPGARVSLRDGTIATSDAHGTFRMPGICASSRANISAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELHGLRPDQAGAYHCKAWNDAGAVRSGIARLTVLAPGQPACDPRPREHLIKLPDDCGQPGRGPTYLDVGLCPDTLCPSPAGSRPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAADSREPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEIKAMRKKAPIILDASQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGVVEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRTYGMFSVDLRAAGSAEQLQTGLVAVRVATDQIRMPGHLEALKLWSLNPDTGLWEEESSFQRERQRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATLGGEELEPAPSRPRPLPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRSLRECQEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPSAALGDIRREMGDVTRARASSPLRTRRGRAQQ >KAB0361517.1 hypothetical protein FD754_005673 [Muntiacus muntjak] MASLPTLLCLCVAAAHLAGARGTPDTEEPTVTAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCPSPARDACPGRPSEAQKCVRPRCPDPNTCGCPDHILLGSVVTPSGRPLPGARVSLRDGTIATSDAHGTFRMPGICASSRANVSAQMDGFSAGMAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLNRRTHRYGAHLELHGLRPDQAGAYHCKAWNDAGAVRSGIARLTVLAPGQPACDPRPREHLIKLPDDCGQPGRGPTYLDVGLCPDTLCPSPAGSRPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAADSREPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEIKAMRKKAPIILDSSQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGAVEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRTYGMFSVDLRAAGSAEQLQTGLVAVRVATDQIRMPGHLEALKLWSLNPDTGLWEEESGFQRERQRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATLGGEELEPAPSRPRPLPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRSLRECQEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPSAALGDIRREMGDVTRARASSPLRTRRGRAQQ >KAB0385514.1 hypothetical protein FD755_000470 [Muntiacus reevesi] MASLPTLLCLCVAAAHLAGARGTPDTEEPTVTAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCPSPARDACPGRPSEAQKCVRPRCPDPNTCGCPDHILLGSVVTPSGRPLPGARVSLRDGTIATSDAHGTFRMPGICASSRANVSAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELHGLRPDQAGAYHCKAWNDAGAVRSGIARLTVLAPGQPACDPRPREHLIKLPDDCGQPGRGPTYLDVGLCPDTLCPSPAGSRPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAADSREPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEIKAMRKKAPIILDSSQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGAVEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRTYGMFYVDLRAAGSTEQLQTGLVAVRVATDQIRMPGHLEALKLWSLNPDTGLWEEESSFQRERQRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATLGGEELEPAPSRPRPLPAAVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRSLRECQEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPSAALGDIRREMGDVTRARASSPLRTRRGRAQQ >OWK11996.1 CILP2 [Cervus elaphus hippelaphus] MASLPTLLYLCVAAAHLAGAR----------------GSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCPSPAGDACPGRPSEAQKCVRPRCPGPNTCGCPDHILLGSVVTPSGRPLPGARVSFRDGTIATSDAHGTFRMPGICASSRANISAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELHGLRPDQAGAYHCKAWNDAGAVRSGIARLTVLAPGQPACDPRPREHLIKLPDDCGQPGRGPTYLDVGLCPDTLCPSPAGSRPRCGEAGSRCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAADSREPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEIKAMRKKAPIILDASQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGVVEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRTYGMFSVDLRAAGSAEQLQTGLVAVRVATDQIRMPGHLEALKLWSLNPDTGLWEEESSFQRERQWARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATLGGEELEPAPSRPRPLPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRSLRECQEAPVTAGHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPSAALGDIRREMGDVTRARASSPLRTRRGRAQQ >KAF4014309.1 hypothetical protein G4228_006190 [Cervus hanglu yarkandensis] MASLPTLLYLCVAAAHLAGAR----------------------ARVVPA-----EASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPL----------------------------------------------------GPNTCGCPDHILLGSVVTPSGRPLPGARVSLRDGTIATSDAHGTFRMPGICASSRANISAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELHGLRPDQAGAYHCKAWNDAGAVRSGIARLTVLAPGQPACDPRPREHLIKLPDDCGQPGRGPTYLDVGLCPDTLCPSPAGSRPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAADSREPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEIKAMRKKAPIILDASQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGVVEAQVTFVDPRNLTSAAAAPSDLRFVDRDGELAPLRTYGMFSVDLRASGSAEQLQTGLVAVRVATDQIRMPGHLEALKLWSLNPDTGLWEEESSFQRERQRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATLGGEELEPAPSRPRPLPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRSLRECQEAPVTAGHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPSAALGDIRREMGDVTRARASSPLRTRRGRAQQ >XP_018112382.1 cartilage intermediate layer protein 2 [Xenopus laevis] MPALLSSLLIFVFL-------------------------------------KISGASEWTSWFNVDHPEGEGDYETVEAVRFYY-PDRLCSRPIALEARTTEWMAPEDTMEVVHSSPEKGFWCSNKEQKDGNLCSNYHVRFKCPLEDYWSHWEAWTPCTRTCGGGRRIRRRVC-TSKKNNCSGRTYQLQKCGKAPCKACRRCNCDSHTLVGKVQSSRGSALHGARVFLKYELLGTTDLRGNIRIAGICSDDHVNVTVVLDGYTSVTLQNVKNGSSSSYFLALLKREEKPYMVQHPYSKIRKEGQKVTFCCEATGNPIPTKYYWYHNSTLLDKQIFKYDKALTLRNLQAVQTGTYQCRASNGLGVVKSSVAQLTIVGKQENSCSKSPQEHLIKLPAGCFQTTTRSLYHNVGKCPNAQCVGSVSSEILCKDKVDYCCGVKQMMLQEVQCPGYILPIMVVKECGCVKCIQPKVLVRGRVTAYDTGEPLRFGQIFVSGENMGFTGYKGEFTLEVPAGTKRLVVTFIDREDKFVETIKVFPFDPKGSTVYQDVKIMRKSQPKNLDPGIINIIPLGTVEAEDPMAEIVIPPYSFTRTSGEVYNGTVKASVTFLDPRNISTASAASSDLNFVNRDGEIAPLRTYGMFAVDFRQEDTNAILLAGKVEVHLNTEQVKMPQHLKEMKLWSLNEETGMWEEESRFQVV-QRKRREERSFLIGQLEIRERRLFNLDVPEHRRCFVKVRAYMNEKFIPSEQLEGVVINLINLEPVAGFSSNPRAWGRFDSVITGKNGACLPAFCDAQRPDAYTAYVTAIMGGEELEAAPSSPKLNPNVVGVSQPYLSKLGYQRSDHEDTAGKKTAFKLNLAKPNPNNLDETSGPIYAYRNLRGCEGAPVSDNHFRFYRVEEDKYEFNVVPFVETDLTSWIGGYLSWWPNPQEFRACYIKIRIQGTQEYMIRSRNAGGSHPRTTGQLYGLRDIRSVRDLHVDRSSAACVEFKCSGMLYDQSVVDRTHVVINPQGSCRIIEINRLLKEYLARHPPVVLGNDTGTFNMLAPVDPLGHNYGIYTVTDQNPKLAKEIAIGRCFDGTSDGFSREMKSTAGVALTFRCQEKPVTHESFFQRLLNNPGETLREIRRGMLENEQSRTRRPIQRRPGQVRR >XP_008267106.1 PREDICTED: LOW QUALITY PROTEIN: cartilage intermediate layer protein 1 [Oryctolagus cuniculus] MAGTKAWVCLVLEVASVLGRRPML-----TQSVRRVQPGKRTPSILAKPADPSESPGEWTTWFNIDHPGGLGDYERLDAIRFYY-GDRVCARPLRLEARTTNWMPAGSNGQVVHGSPHEGFWCLNREQRPGQNCSNYTVRFLCPPERIWSPWSRWSKCSAACGHGVQTRTRTCLAESMALCTEATEEGRLCETQACTDCDACMCQDFLLHGAVSLPGGAPAAGATVYLLNKLLTQTDSNGRFRVPGLCPDGTTILKIMKTKFAPIVLTMPKTRLNVATVNAEFRRAETPYMLTSPQTKARRAGQSVSLCCKATGKPSPDKYLWYHNNTLLHPSLYKHESKLVLRNLRQEQAGEYFCKAQSDAGAVKSQVAQLMVIAPDETPCNPVPESYLIRLPHDCFQNATNSFYYDVGRCPVKTCAGQQDNGLRCQDAE-NCCGISKMKEKEIQCSGYTLPTKVAVQCSCQRCTETRSIVRGRVSAADTGEPMRFGHVYMGNSRVSMTGYKGTFTLHVPQDTERLVLTFVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRRKEPITLEALETNIIPLGEVDGEDPVAELEIPPKSFFRQNGEPYTGKVKASVTFLDPRNVSTATAAQSDLNFVNDEGDTLPLRTYGMFSLDFTDEATAEPLNAGKVKVHLDSTQVKMPEHVAAMKLWSLNPDTGLWEEEGDFKL--RRNKREQRTFLVGNMEIRERRLFNLDVPESRRCFLKVRAYRSERFLPSEQIQGVVVSAINLEPRAGFSSNPRAWGRFDSVITGPNGACVPAFCDDQSPDAYSAYVLASLAGEELEAVESSPKFNPNAIGVPQPYLNKLKYRRTDHEDPQVKKTAFQISMAKPRPNSAEESNGPIYAFENLRACEDAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIVGAVEVNVRSRNMGGTHRRTVGKLYGIRDVKSTRDRDQPNVSSACLEFKCSGMLYDQDRVDRTLVKVIPQGSCQRASVNSMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVTDQDPRTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCAERQVGRQSAFQYLQSTPARTPAA-----GTGQGGGQRQPELRFSGAAQQ >XP_009251325.1 cartilage intermediate layer protein 2 isoform X1 [Pongo abelii] MASLLPLLCLCVVAAHLAGARDATPTEEPMATALGLERRSVYPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEASWGAWGPWGPCSGSCGPGRRLRRRHCPSPAGDACPGRPLEAQKCLRPRCPSLDTCECPDHILLGSVVTPSGQPLPGARVSLRDGTVATSDAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQANGSIS-VVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRAHGYGAHLELRGLRPDQAGIYHCKAWNEAGAVRSGAARLTVLAPGQPACDPRPREYLIKLPEDCGQPDSGPAYLDVGLCPDTRCPSLAGSGPRCGDASSRCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAADSGEPLRFARILLGQEPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDPRGAGVYHEVKAMRKKAPVILDASQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGPVEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVAVRVAASQIHMPGHVEALKLWSLNPETGLWEEESGFRREGPRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSLPRPLPATVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERPGTSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLRDYLTRHPPPVPAEDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMSEVAQARASGPLRTRRGRVRQ >XP_003123618.1 cartilage intermediate layer protein 2 isoform X1 [Sus scrofa] MASLPTLLCLCVAAAHLAGARGTTTPEEPTATAWDLEGPSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGAWGPWGPCSGSCGPGRRLRRRRCPSSAGDACPGRPLEAQKCIRSPCPSLNICGCPDHILLGSVVTPTGRPLPGARVSLRDGTVATSNAHGTFRMPGVCASSRVNVSAQMDGFSAGMAQAQANSSISAVVTVVLKKLEKPYLVKQPESRVREAGQNVTFCCKASGTPIPKKYSWFHNGTLLDRRTHRYGAHLELHGLHPDQAGTYHCKAWNDAGAVRSGTARLTVLAPGQPACDPQPREHLIKLPDDCSQPGSGPTYLDVGLCPDTLCPSATGSSPRCGDAGSRCCSVRRLESRKIRCSGYNLPVKIVAECGCQKCLPRRGLIRGRVVAADSGEPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVITFVDTSGQFVDTVRVLPFDPRGAGVYHEVKAMRKKAPVILDASQSNTIPLGELEDEAPLGELVIPPGAIRRADGEPYVGSVEARVTFVDPRDLTSAAAAPSDLRFVDSDGELAPLRTYGMFSVDLRAPDSTEQLQTGPVAVRVAASQIRMAGHVEALKLWSLNPDTGLWEEESGFQRERQRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPNEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDTDRPDAYTALVTATLGGEELEPATSRPRPLPATVGVAQPYLDKLGYRRTDHDDPSLKRNGFRINLAKPRSGDPDEANGPVYPWRNLRECQEAPVTANHFRFARVEADKYEYNVVPFREGVPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTQGQLYGLRDARSVRDPERPSMSAACVEFKCGGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPPAPADDLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPAAGRPSLFQRLLESPSTALGDIRREMGEVARARASVPLRTRRGRARQ >XP_003817771.2 cartilage intermediate layer protein 2 [Pan paniscus] MASLLPLLCLCVVAAHLAGARDATPTEEPMATALGLERRSVYTGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEASWGAWGPWGPCSGSCGPGRRLRRRHCPSPAGDACPGRPLEAQKCVRPRCPSLDTCECPDHILLGSVVTPSGQPLLGARVSLRDGTVATSDAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQANGSIS-VVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRAHGYGAHLELRGLRPDQAGIYHCKAWNEAGAVRSGTARLTVLAPGQPACDPRPREYLIKLPEDCGQPGSGPAYLDVGLCPDTRCPSLAGSSPRCGDASSRCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAADSGEPLRFARILLGQEPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDPRGAGVYHEVKAMRKKAPVILHASQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGPVEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVAVRVAASQIHMPGHVEALKLWSLNPETGLWEEESGFRREGPRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSLPRPLPAAVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERPGTSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAINGLLRDYLTWHPPPVPAEDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMSEVAQARASGPLRTRRGRVRQ >XP_003982175.1 cartilage intermediate layer protein 2 [Felis catus] MASLPPLLCLFVAAAHLAGARVTTPPEEPTATAWGFEGPSLRPGQPSPALEDWEEASQWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSTVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGAWGPWGPCSGSCGPGRRLRRRRCPSPSGDACPGRPLEAQKCVRPPCPSSKTCTCPDHILLGSVVTPSGRPLPGARVSLRDGTVAITDAHGTFRIPGVCASSRANISAQMDGFSAGLGQAQANGSISAVVTVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRREHRYGAHLELRGLRPDQAGTYHCKAWNDAGTVRSGSARLTVLAPGQPACNPQPQEHLIKLPDDCGQPGSGPAYLDVGLCSDTLCPSPAGSSSRCGDSGSRCCSVRRLESKEIHCSNYVLPVKVVAECGCQKCLPPRGLVRGRVVATDSGEPLRFAQILLGREPIGFTSYQGDFTIEVPPSTQRLVVTFVDPSGEFMDTVRVLPFAPRGGGVYHDVKAMRKKAPVILDASQSNTIPLGELEEEDPLGELVLPPGAFRRADGAPYTGAVEARVTFVDPRDLTSAAAAPSDLRFVDSDGELAPLRTYGMFAVDLRAAGSAEQLQAGPVAVRVNAGQIHMEGHVEALKLWSLNPDTGLWEEESGFQREGPRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPNEQVEGVVVTLVNLEPAPGFAANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSRPRPHAATVGVAQPYLDKLGYRRTDHDDPALKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQEAPVTASHFRFARVEADKYEYNVVPFREGVPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTQGQLYGLRDARSVRDPEHPGTSAACVEFKCSGMLFDQRQVDRTLVTITPQGSCRRVAVNGLLRDYLARHPPAAPADDPAAFAMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMGEVTRAQAAGPLRTRRGRARQ >XP_027825142.1 cartilage intermediate layer protein 2 [Ovis aries] MASLPTLLWLCVAAAHLAGARGTPDAEEPTVTAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRSCSNYHVRFRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCPSPAGDACPGRPSEAQKCVRPRCPGPNTCGCPDHILLGSVVTPSGHPLPGARVSLRDGTVATSDAHGTFRMPGVCASSRANVSAQMDGFSAGMAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELHGLRPDQAGTYHCKAWNDAGAVRSGTARLTVLAPGQPACDPRPQEHLIKLPDDCGQPGRGPTYLDVGLCPDTLCPSPAGSSPRCGDAGSRCCSVSRLESRKVHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAADSSEPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEVKAMRKKAPIILDARQSNTISLGEMGEEAPLGELVIPPGAFRSADGQPYTGAVEAQVTFVDPRNLTSAAAAPSDLRFVDADGELAPLRTYGMFSVDLRAAGSAEQLHTGLVAVRVAADQIRMPGHVEALKLWSLNPDTGLWEEESGFQRERRRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFSPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTAVVTATLGGEELEPAPSRPRPLPAAVGVAQPYLDRLAYRRTDHDDPALKRSGFRINLAKPRPGDPSEANGPVYPWRSLRECQEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGTHPQTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTVMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPSAALGDIRREMGQASRARASGPLRTRRGRAQQ >KYO23576.1 cartilage intermediate layer protein 2 [Alligator mississippiensis] MRESECPTV---------------------------------------------SGTEWTSWFNIDHPGGDGDYETLEAIRFYY-QGRVCAQPLALEARTTEWELPRDVGEFVHASPRKGFWCINQEQPEGRTCSNYHVRFLCPL----------------------------------------------------DCSGCTCPDHTLLGTVVSAEGSALANARVALQDATLARTDQRGRFRVPGVCAGSAANVTVQLERFSPGAAPVIASGPQTSTVQVTLRRLEKPYMVMHPDSKVRTAGQQVTLCCKASGTPVPRKYYWYHNGTLLDRKVYRYDGRLVLKELQPRHAGAYHCKASSDAGAIKSAIARLTVLGKGQPSCRARPEQSLIRLPGECFPDASGSPYYDVGRCPATRCAGSLAEKRQCRDDKERCCGVRRMELREVRCAGYVLPIKVVAECGCETCAQPKVLVQGRVVAADDGEPLRFGQVFLGQKSIGFTGYQGAFTIEVPPGTRRLVVRFVDPLQKFLDTVKVLPFDSQGSAVYQDVRVMRKKTPMDLDAAQTNALPLGELAGEGPVGELVFPAGAFRRASGEPYNGTVKASVTFLDPRDAATVATASSDLSFVNAEGDMVPLRTYGMFAVDLRARAGGERLQASGVEVRMDAGQVRMPEHLPKMKLWSLNPTTGLWEEEGALRP--RRGKREERTFLVGNLEIRERRLFNLDVSENRRCFVKVRAYGSEKFSPLEQLQGVVVTLVNLEPRPGYPANPRAWGRFDSAVTGRNGACLPAFCDGQRADAYTAYVTATLGGEELEAAASRPSPDPSTVGVSQPYLSKLGYRRLDHTDPRAKKTAFRVNLAKPNPNNVDEVNGPLYPYRSLRECEEAPVSANHFRFSRAEVDKYEYNVVPFEEGDLTSWTRDYLAWWPNPQEFRACYIKVKVEGPQEYMVRSRNVGGSHPWTQGQLYGLRDARSVKDPELEHSSAACVEFKAAA------------TARPPTASCGST------------------------------------------------------------------------------------------------------------------------------------- >XP_018871353.1 cartilage intermediate layer protein 2 isoform X1 [Gorilla gorilla gorilla] MASLLPLLCLCVVAAHLAGARDATPTEEPMATALGLERRSVYPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEASWGAWGPWGPCSGSCGPGRRLRRRHCPSPAGDACPGRPLEAQKCVRPRCPSLDTCECPRHILLGSVVTPSGQPLLGARVSLRDGTVATSDAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQANGSIS-VVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRQAHGYGAHLELRGLRPDQAGIYHCKAWNEAGAVRSGTARLTVLAPGQPACDPRPREYLIKLPEDCGQPGSGPAYLDVGLCPDTRCPSLAGSSPRCGDASSRCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRIVAADSGEPLRFARILLGREPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDPRGAGVYHEVKAMRKKAPVILHASQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGPVEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVAVRVAASQIHMPGHVEALKLWSLNPETGLWEEESGFRREGPRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSVNPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSLPRPLPATVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERPGTSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLRDYLTRHPPLVPAEDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMSEVAQARASGPLRTRRGRVRQ >XP_011471792.1 cartilage intermediate layer protein 2 [Oryzias latipes] MLELNKLRLLLSLLAYVTLGQG---------SLRTRNISDRSKRTASNRFSDTQGVTEWTSWFNIDHPGGNGDYERLEAIRFYY-RERVCSRPTAIEARTSDWLTAADTGEVVHSSLEKGFWCINKEQPKGNICSNYHVRFQCPPTAKWSPWGHWGMCSVTCGGGQRTRRRTCRTSVSVQCAGRSVDIQKCGKTPCPDCSLCVCEDHVLHGDVHSVTGVPVEGARVSLASALHAQTNAKGQFVLAGVCSSTSSSIIIKKEKYVPTIVSTSSNTTGLSRLKAVLRSAEKPYVVKHPEDKVRYEGGRVLLCCSATGSPAPSKYYWYHNGTLLDRKIYKYEEDLMLQDLKFEHSGEYYCKTSNPAGSIKSSVAILSVIAKGTPACDSTPEAHLIRLPLDCVQPGTQSKYYNAGRCPHNKCAGSLEFDMRCKDGAGFCCGVQSMESRVIDCGSYSLPIRAVTKCICQKCMQPTVIVRGRVVTADNNEPLRFGHIYIGKERVGTTGYQGGFTLKIAQDTQRLVVNFVDPTETFLNTPKVFIFDKKSGSIYHDVKVMRKQKPIDINSRETNVIDLGEIKGEDPIGQLVIPPNSFHKDTGEVYEGTVKASVTFIDPRNITTAAATPGDLNFVDDEGDMLPLRTYGMFSVDFRDNSSNKVLGAGAVQVLLDTQHVKMQEHIPQMKLWSLNPDTGVWEEESKFSYSTGRSKREERTFLIGNMEIRERRLFNLDVPESRRCYVKVRAYMSDKFLPTEQLEGVVITLINLEPKPGYSSNPRAWGRFDSVITGPNGACLPAFCDAMRPDAYTAYVTAMLNGEELEAAPSTPKMNPNIIGVSKPFLDKLDYQRSDHTDSALKKTAFKINLAKPNQNNLDETNGPIYPYQSMIACENAPIDANHFRFFRVEKDKYEYNVVPFEENDLTSWTGDYLSWWPNPQEFRACFIKVRIHGQKEVMVRSRNHGGTHPETKDKLYGIRDIRSTRDMREANTSAACVEFKCSGMLYDQSEVDRSLISVLPQGNCRRININNLLQEYLIKHPPFTQSNGSHSFTMMAPVDPLGHNYGIYTVTDQNPRVAKEIAIGRCFDGTSDGFSREMKSDSGVALTFSCPERKINRQSLFQRLQTNPGQTLSQMARDMRDFQGTQSRRMSARRTVPVRE >XP_005505580.2 LOW QUALITY PROTEIN: cartilage intermediate layer protein 2 [Columba livia] -------------------------MENDSEPGKSDGGRKPWKAAPSLAELDLDRGAEWTSWFNIDHPGGDGDFESLDAI---X-XXXXXXXXXAIQARTTAWELPEEVGEVVHASPKKGFRCLNKEQPQGKTCSNYHIRFLCP---------------------------------------------------------------------------------------------------------------------------------------------LEKPYMVLHPKAKVRVAGQEVTFCCKASGTPVPKKYYWYHNGTLLDRKVLRYGSRLVLRGVTPEQTGTYHCKASTEAGVTKSAPAQLTVLAQGQQSCKPEPEPSLVELPSECPQDATGSRYYNVGRCPPTPCPGSPAKESGCGGGPGRCCGVRRMELREIPCAGSLLPVKVVAECGCGPCAQPRVLVQGRVTAADTGEPLRFGQIFLGGRKVGFTGYKGSFTIEVPPDTQRLVVRFVDRHQRFIDAIKVLPFDRRGGTVYQEVKMLRKKEPVELDSNQSNVIPLGEARGQEPIGELVLPAGTFLHPSGEVFKGTVKASVTFLDPRDMATASAASSDLSFTNAEGEIVPLRTYGMFAVDFQEGETGAALQTGPVEVRMDAGQVWMPEHLQKMKLWSLNPETGLWEEEGVL----XXXKREERTFLVGNLEIRERRLFNLDVPEDRRCFVKVRAYANEKFNPYEQLEGVVISLINLEPQPGYPANPRAWGRFDSVVTGPNGACLPAFCDSQRPDAYSAYVTATLGGEELEAVASSPKLNPNTIGVSQPYLGKLGYRRSDHDDPNLKKTAFQINVAKPDPNNVDETNGPIYPYRSLEECEEAPVSANHLRFYRVEVDKYEYNVVPFKESDLTSWTGDYLSWWPNPQEFRACFIKVQIEGPQEYMVRSRNLGGTHPRTRGQLFGLRDTRSVRDMLLENTSGACVEFKCSGMLFDQSLVDRTLVSIIPQGSCRRTAVNSLLRDYLSRHPPVAENNHTAAFTMLAPVDPLGHNYGIYTVTDQNPRLAKEIAIGRCFDGTSDGFSREMKADTGTAVTFTCQERPAGRQSFFQRLLTAPAQALDEIRREMGAGEMRPSAARRRQRTGRSRG >XP_017906987.1 PREDICTED: cartilage intermediate layer protein 2 [Capra hircus] MASLPTLLCLCVAAAHLAGARGTPDAEEPTVTTWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRSCSNYHVRFRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCPSPAGDACPGRPSEAQKCVRPRCPGPNTCGCPDHILLGSVVTPSGRPLPGARVSLRDGAVATSDAHGTFRMPGVCASSRANISAQMDGFSAGMAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVRQAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELRGLRPDQAGTYHCKAWNDAGAVRSGTARLTVLAPGQLACDPRPQEHLIKLPDDCGQPGRGPTYLDVGLCPDTLCPGPAGSSPRCGDTGSRCCSVRRLESRKIHCSGYTLPVKVVAECGCQKCLPLRGLIRGRVVAADSSEPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEVKAMRKKAPIILDARQSNTISLGEMGEEAPLGELVIPPGAFRRADGQPYTGAVEAQVTFVDPRNLTSAAAAPSDLRFVDADGELAPLRTYGMFSVDLRAAGSAEQLHTGLVAVRVAADQIRMPGHVEALKLWSLNPDTGLWEEESGFQRERRRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTAVVTATLGGEELEPAPSRPRPLPAAVGVAQPYLDRLAYRRTDHDDPALKRSGFRINLAKPRPGDPTEANGPVYPWRSLRECQEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGTHPRTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTVMPQGSCRRVAVNGLLQDYLTRHPPPAPSDDLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPAAGRPSLFQRLLESPSAALGDIRREMGQASRARASGPLRTRRGRAQQ >XP_025052336.1 cartilage intermediate layer protein 2 [Alligator sinensis] MGALAPAL-LFLAALHCAGARAE-PEENDSRLAKTKPPGKRRKKVPNGTSPDVDAGTEWTSWFNIDHPGGDGDYETLEAIRFYY-QGRVCAQPLALEARTTEWELPRDVGEFVHASPRKGFWCVNQEQPEGRTCSNYHVRFLCPLEATWGPWGAWSPCSKTCGSGRRLRRRSCKKSRTSRCAGRPSEVQKCARTPCPDCSGCTCPDHTLLGTVVSAEGSALANARVTLQDATLARTDQRGRFRVPGMCAGSTANVTVQLERFSPGAAPVIASGPRMSTVQVTLRRLEKPYMVMHPDSKVRTAGQQVTLCCKASGTPVPRKYYWYHNGTLLDRKVYRYDGRLVLKELQPRHAGAYHCKASSDAGAIKSAIARLTVLGKGQPSCRARPEQSLIRLPGECFPDASSSPYYDVGRCPATRCAGSPAEERQCRDDEERCCGVRRMELREVRCAGYVLPVKVVAECGCD-------------------------QVFLGQKSIGFTGYQGAFTIEVPPDTRRLVVRFVDPLQKFLDTVKVLPFDSQGRAVYQDVP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELEAAASRPSPDPSTVGVSQPYLSKLGYRRLDHTDPRAKKTAFRVNLAKPNPNNVDEVNGPLYPYRSLRECEEAPVSANHFRFSRAEVDKYEYNVVPFEEGDLTSWTRDYLAWWPNPQEFRACYIKVKVEGPQEYMVRSRNVGGSHPWTQGQLYGLRDARSVKDPELEHSSAACVEFKCSGMLFDHSGMDRTLVSIVPQGSCYRTATNSLLREYLGRHPPAAPNNDTRAFHMLAPVDPLGHNYGIYTVTDQNPRLAKEIALGRCFHGTSDGFSREMKSEVGTAVTFLCQERPAGRQSLFQRLLEAPAEDLTEIRQEMGRSGQ---------------- >XP_015827098.1 PREDICTED: cartilage intermediate layer protein 2 [Nothobranchius furzeri] MLELTKLALLLSFLTSVALGQG---------SVRSRMLSDRSKRTTFQAFSDPQGVTEWTSWFNIDHPGGNGDYERLEAIRFYY-RERVCVRPTAMEARTTDWVAAADTGEVVHSSLEKGFWCINKEQPLGRACSNYHVRFQCPPTAKWSPWGPWGMCSVTCGGGRRTRRRTCRTSATIQCKGRPVEVHKCGKSPCPDCSSCVCEGHMLQGDVQGVAGFPIAGAAVGLASVIRARTDAKGQFRLPGVCSSSSMLLTIRKEKFVPINVSTSSNTTGLSWLRAVLKSAEKPYIVKHPEDKVRYEGGRLLMCCTATGSPAPDKYYWYHNGTLLDRRVYKYEEDLVLRDLKLEQSGEYYCKASSPAGSIKSAPALLTVVGKGTPACNSTPEFHLIRLPMDCIQLGTDSKYYNAGRCPHNQCAGSLDYDMRCRDGAGFCCGVQKMESRIIDCGNYKLPIRAVSHCGCQKCMQPTVLVRGRVVTADNGEPLRFGHIYIGKERVGTTGYQGGFTLQITPDTQRLVVNFVDPTQRFLDTPKVFILDKKGGSIYHDVKVMRKQTPIDIDAGETNFIDLGEIKGEDPIGQLVIPPNSFHKDNGETYEGTVKASVTFIDPRNITTAAAAPGDLNFVDDEGDMLPLRTYGMFSVDFRDESNKEVLGAGAVQVLLDTQHVKMQEHIPEMKLWSLNPDTGVWEEESDFSYSTGRSKREERTFLIGNMEIRERRLFNLDVPESRRCYVKVRAYMSDKFLPTEQLEGVVISLINLEPKPGYSSNPRAWGRFDSVLSGSNGACLPAFCDAMRPDAYTAYVTAMLGGEELEAAPSSPKMNPNIIGVSQPYLDKINYQRSDHDDPALKKTAFKINLAKPNQNNFDETNGPIYPYQNLLGCENAPVDANHFRFFRVEKDKYEYNVVPFEETDLTTWTRDYLSWWPNPQEFRACFIKIKIHGQKEVMVRSRNLGGTHRETRGKLYGIRDIRSTRDMREANTSAACLEFKCSGMLFDQAEVDRSIISVLPQGNCRRISINGLLQEYLIKHPPVAQNNESHAFTMLAPVDPLGHNYGIYTVTDQNPRVAKEIAIGRCFDGTSDGFSREMKSDYGVAVTFSCPEKKINRESLFQRLQTNPGQTLAQMARDMRELEGTQSRRVSARRRASIRA >XP_016792564.1 cartilage intermediate layer protein 2 [Pan troglodytes] MASLLPLLCLCVVAAHLAGARDATPTEEPMATALGLERRSVYTGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEASWGAWGPWGPCSGSCGPGRRLRRRHCPSPAGDACPGRPLEAQKCVRPRCPSLDTCECPDHILLGSVVTPSGQPLLGARVSLRDGTVATSDAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQANGSIS-VVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRAHGYGAHLELRGLRPDQAGIYHCKAWNEAGAVRSGTARLTVLAPGQPACDPRPREYLIKLPEDCGQPGSGPAYLDVGLCPDTRCPSLAGSSPRCGDASSRCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAADSGEPLRFARILLGQEPIGFTAYQGDFTIEVLPSTQRLVVTFVDPSGEFMDAVRVLPFDPRGAGVYHEVKAMRKKAPVILHASQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGPVEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVAVRVAASQIHMPGHVEALKLWSLNPETGLWEEESGFRREGPRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSLPRPLPATVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERPGTSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAINGLLRDYLTRHPPPVPAEDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMSEVAQARASGPLRTRRGRVRQ >XP_020766171.1 cartilage intermediate layer protein 2 [Odocoileus virginianus texanus] MASLPTLLCLCVAAAHLAGARGTPDTEEPTVAAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCPSPAGDACPGRPSEAQKCVRPRCPGPNTCGCPDHILLGSVVTPSGRPLPGARVSLRDGTIATSDAHGTFRMPGICASSRANVSAQMDGFSAGTAQAQANSSMSAVATVVLNKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELHGLRPDQAGAYHCKAWNDAGAVRSGTARLTVLAPGQPACDPRPREHLIKLPDDCGQPGRGPTYLDVGLCPDTLCPSPAGSRPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKIVAECGCQKCLPLRGLIRGRVVAADSREPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEIKAMRKKAPIILDASQSNTISLGEMGDEAPLGELVIPPGAFRRADGQPYTGAVEAQVTFVDPRNLTSVAAAPSDLRFVDRDGELAPLRTYGMFSVELRAAGSAEQLQTGLVAVRVATDQIRMPGHLEALKLWSLNPDTGLWEEEGGFQRERQRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATLGGEELEPAPSRPRPLPATVGVAQPYLDRLAYRRTDHDDPALKRTGFRINLAKPRPGDPTEANGPVYPWRNLRECQEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNVGGSHPRTQGQLYGLRDSRSVRDPQHPSSSAACVEFKCSGMLFDQRQVDRTLVTVTPQGSCRRVAVNGLLQDYLARHPPSAPAEGLAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPSAALGDIRREMGDVARARASSPLRTRRGRAQQ >XP_030289610.1 cartilage intermediate layer protein 1-like [Sparus aurata] MLGLNKVALLLSFMASLALGQG---------SVRTRRQLDRSRRVALNTFTDTQGVTEWTSWFNIDHPGGNGDYERLEAIRFYY-RERVCVRPMAMEARTTDWVAAADTGEVVHSSLEKGFWCINKEQPHGRICSNYHVRFQCPPTAKWSPWGRWGTCSVTCGGGRRIRRRTCRTSLTIQCTGRPVEVQKCGKSPCPDCSRCVCDSHVLQGEVLTVTGVPVAGALVALASAIRARTDAKGQFGLKGICSSSSTLISIRKEKYAPVTVSTSSNTTGLSWVQALLKSAEKPYIVKHPEDKVRYEGGRVLLCCKATGSPAPDKYYWYHNGTLLDRKVYKYEEDLVLRDLKPEQSGQYYCKTSSPAGSIKSSPSLLTVIAKGTPACNSTPETHLIRLPMDCVQPGTVSKYYNAGRCLLNKCAGSLDFDMRCRDGSAFCCGVQNMESRIIDCGSYSLPIRAVTQCGCQKCVQPTVLVRGRVVTADNNEPLRFGHIYIGKERVGTTGYQGGFTLQISPDTQRLVVHFVDPTQKFLDTPKVFILDKKGGSIYHDVKVMRKQMPIDINAGEINSINLGEIKGEDPIGQLVIPPNSFHKDNGEIYEGTVKASVTFIDPRNITTAAAAPGDLNFVDDEGDMLPLRTYGMFSVDFRDETNKEVLGAGAVQVLLDTQHVKMQEHIPKMKLWSLNPDTGVWEEESDF-YATGRSKREERTFLIGNMEIRERRLFNLDVPENRRCYVKVRAYMSDKFLPTEQLEGVVISLINLEPKPGYSSNPRAWGRFDSVITGPNGACLPAFCDAQRPDAYTAYVTAMMGGEELEAAPSSPKMNPNIIGVSQPYLDKIDYQRSDHEDPALKKTAFRINLAKPNQNNLDETNGPIYPYQNLIACENAPIDANHFRFFRVEKDKYEYNVVPFEENDLTTWTGDYLSWWPNPQEFRACFIKVKIQGQKEVMIRSRNLGGTHRETKAKLYGIRDIRSTRDMREANTSAACVEFKCSGMLFDQAEVDRSLISVLPQGNCRRINTNSLLQEYLIKHPPVAQNNESHAFTMLAPVDPLGHNYGIYTVTDQNPRVAKEIAIGRCFDGTSDGFSREMKSDSGVALTFSCPERKINRESLFQRLQTNPGQTLSQMARDMRESEGSQSRRVSTRRRVSTRI >XP_040176473.1 cartilage intermediate layer protein 2 isoform X1 [Rana temporaria] MLACHFALLLSVLF---------------------------------------TGATDWTSWFNVDHPGDDGDFETIEAIRFYY-PHRLCLRPVAIEARTTEWATPKDTKEVVHTDPEKGFWCINKEQKKGYNCSNYHVRFQCPLVGRWSSWGAWTPCTKTCGGGKSVRRRIC-SSKTAPCSGRTFQIQKCGRTLCRLCPGCHCNNHTLLGKIQSIHGFVLHNAKVFMNKKILGVTDQHGLFMLKGVCMDTPSNITIKMDGFSSVTLQSMRKEPKVSYFEAALKKLEKPYMVQNPYSKIRRIGHKVTMCCEATGNPVPTKYYWYHNGTLLDKHTLKYDKSLTLRNIQATHGGIYQCKASNGVGVIRSSVAHLNVISKSESLCNKSPNEHLIKLPMDCFQNKTGSYYYNVGRCPNTQCMDHLSSNLQCKDEINYCCGVKQMKLQEVKCPGYILPVMVVVQCGCAECSRYKIMVRGRVTAYDTGEPLRFGQIFLSGENKGFTGYKGDFTLEVPEGTKRLVVTFVDRQEKFVETTKVIPFDPKGNTVYQDVKVMRKKDPTDLNPRVTNIISLGDLLGEDPIGEIIIPPNSFRRTSGEPYNSTVKASLTFLDPRNISSASAASSDLNFVSRDGDISPLRTYGMFHLDFREDSTNSLLQTGKVEVRLDVEQIKMPQHVKEMKLWSLNPQTGLWEEESHFRLP-KRKKREERSFLIGQLEIRERRLFNLDVPEFRRCFVKVRTFMNEKFMVNEQLEGIVVTLINLEPMPGFSSNPRAWGRFDSVVTGSNGACLPAFCDAVKPDAYSAYVTATMGGEELEAAPSSPKRNPNVIGVTQPYLSKLNYQRTDHDDSAGKKTAFKINLAKPNPNSLAENRGPIYAYRNLQGCEEASILDNHFRFFRAEEDKYEYNVVPFDETDLTSWIGSYLSWWPNPQEFRACYIKIGIQGPQEYMVRTRNIGGTHTHTVGQLYGLRDTRSVRDLEVESSSAACLEFKCSGMLFDQDLVDRTLVTVTPQGSCHVTKINRLLEEYLSRHPPLALGNNTETFNMLAPVDPLGHNYGIYTVTDQNPRLAKEIAIGRCFDGTSDGLSREMKSQVGIAVTFRCQEKPITRKSLFHRLLNNPGETLSEIRQNMQENEQSQSRKPSQRRPRMAQS >XP_039261724.1 cartilage intermediate layer protein 1-like [Styela clava] MQNVIRCKIISWAVLAFLG-----------------------------------AATQ-------SYVGGNGGYANITSV--------------------------------------------------------------VPKFKPWREWSTWSQCDVSCGGGMQERVRKCRQDKSSKCFGREIESRPCGDAPCG-TNTVSCDT---VGTVTDSLNIPLEGVEICLGSITITHTNEEGFFSVEGICADSEAHLLARKNKYVTTRIRLKVNETGRAFATVKLLELVKPTIYYHPESKSRMIGQSVKFCCKARGSTKDHLFTWYHNGNVVDANLYSRDGTLEIRTLRLDDAGEYWCKVSSKTSFAKSQTAVLSVFESEQNACDEKPGVKLIRLPNDCSMASSNKTYFDVGMCSSVECPAKYADSEGCGETMATCCGPSERKEINLNCRDFVLPIYKTTKCGCQECVKPVIKVRGRAYGNDPTDPLRYGYVERSGKRIGRTSYDGGFTVNVPHGSKRLVLTFIDRFGKLMTTTKVVSFKEDGGVTFHDIKMPQKSPEKSFGSQERSVTSLNGVRGQNSVAQIVTAPNGFVRKDGKPYTGKVRASVTFIDPRNETSYQESPTDLAFIDDNGESLPLQTYGMFEMDFRDEDLNE-LNVANAKIVLDQNQMVSTSHARKLKLWSLNLENGMWEEEENFKEMEKRKKREATTFFVGNLEVRERRLYNLDVPVENRCWLKVRAYRSPDFDPNEQVEGVDIVAINMEPKGGFRGNPSAWGRFDSTLTSKYGACVRVFCHEDKPDVYKAIVTATLSSEELYAAPSGHPVNPKVVGVQGDILRALDYRRSDHSLATGKKTSFQINLPKPRPE--VNYTGPIYPEENYAECVRAPVTDNHFRFYRTEDFLYEYNTVYMDEHNCITWTPHYLNWWPKPLEYRACYIKVHVSGLST-VIRAKSMGGTHPETRGKLYGIRDDRSVLAQRLEGDSAACIEFKCSGKLYDMEEPDRTLVSVIPQGECQLHRMNGQLSQYLTEHPPAVEGESASEFRMYAPPDPLGHNYGIYTVTDDDPLIAKKTALGRCYAGSSDTTSRIMHARKGVAIYYWCTDRN------------------------------GEIELP----------
PhyML tree of selected proteins (XP_030289610_1_cartilage_intermediate_layer_protein_1_like__Sparus_aurata_:0.03753626,(XP_011471792_1_cartilage_intermediate_layer_protein_2__Oryzias_latipes_:0.12494434,XP_015827098_1_PREDICTED__cartilage_intermediate_layer_protein_2__Nothobranchius_furzeri_:0.07292625):0.02712561,(tr_F1Q5N7_F1Q5N7_DANRE_Cartilage_intermediate_layer_protein_2_OS_Danio_rerio_OX_7955_GN_cilp2_PE_4_SV_3:0.152352,((XP_039261724_1_cartilage_intermediate_layer_protein_1_like__Styela_clava_:1.54234745,XP_008267106_1_PREDICTED__LOW_QUALITY_PROTEIN__cartilage_intermediate_layer_protein_1__Oryctolagus_cuniculus_:0.42280305):0.22195315,((XP_040176473_1_cartilage_intermediate_layer_protein_2_isoform_X1__Rana_temporaria_:0.25779917,XP_018112382_1_cartilage_intermediate_layer_protein_2__Xenopus_laevis_:0.20667623):0.2690498,(((XP_005505580_2_LOW_QUALITY_PROTEIN__cartilage_intermediate_layer_protein_2__Columba_livia_:0.11865638,XP_015155600_3_cartilage_intermediate_layer_protein_2__Gallus_gallus_:0.10426193):0.17917263,(XP_025052336_1_cartilage_intermediate_layer_protein_2__Alligator_sinensis_:0.0093152,KYO23576_1_cartilage_intermediate_layer_protein_2__Alligator_mississippiensis_:0.05239958):0.21008905):0.06395655,((XP_003982175_1_cartilage_intermediate_layer_protein_2__Felis_catus_:0.02749061,XP_541920_2_cartilage_intermediate_layer_protein_2_isoform_X1__Canis_lupus_familiaris_:0.04433549):0.00946337,(((NP_081094_2_cartilage_intermediate_layer_protein_2_precursor__Mus_musculus_:0.03645793,NP_001100777_1_cartilage_intermediate_layer_protein_2_precursor__Rattus_norvegicus_:0.02034156):0.20984098,(XP_009251325_1_cartilage_intermediate_layer_protein_2_isoform_X1__Pongo_abelii_:0.00370369,(XP_018871353_1_cartilage_intermediate_layer_protein_2_isoform_X1__Gorilla_gorilla_gorilla_:0.0057224,(sp_Q8IUL8_CILP2_HUMAN_Cartilage_intermediate_layer_protein_2_OS_Homo_sapiens_OX_9606_GN_CILP2_PE_2_SV_2:0.0018917,(XP_016792564_1_cartilage_intermediate_layer_protein_2__Pan_troglodytes_:0.00094534,XP_003817771_2_cartilage_intermediate_layer_protein_2__Pan_paniscus_:0.00189212):0.0009406):0.00095691):0.00202369):0.04138567):0.02434414,(XP_003123618_1_cartilage_intermediate_layer_protein_2_isoform_X1__Sus_scrofa_:0.04127038,((NP_001179457_1_cartilage_intermediate_layer_protein_2_precursor__Bos_taurus_:0.01802171,(XP_017906987_1_PREDICTED__cartilage_intermediate_layer_protein_2__Capra_hircus_:0.00892801,XP_027825142_1_cartilage_intermediate_layer_protein_2__Ovis_aries_:0.00791435):0.0111935):0.00437943,(XP_020766171_1_cartilage_intermediate_layer_protein_2__Odocoileus_virginianus_texanus_:0.01316194,((KAB0361517_1_hypothetical_protein_FD754_005673__Muntiacus_muntjak_:0.00207669,KAB0385514_1_hypothetical_protein_FD755_000470__Muntiacus_reevesi_:0.00348305):0.00278629,(XP_043323422_1_cartilage_intermediate_layer_protein_2_isoform_X1__Cervus_canadensis_:0.00000001,(KAF4014309_1_hypothetical_protein_G4228_006190__Cervus_hanglu_yarkandensis_:0.00523351,OWK11996_1_CILP2__Cervus_elaphus_hippelaphus_:0.00284935):0.00094875):0.00347632):0.00210484):0.01086941):0.03958608):0.02389488):0.01920842):0.45018898):0.14003008):0.1403864):0.22123619):0.08337534);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)