PB0078

DATABASE

Click here to access PB0078 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0078	P10915	Hyaluronan and proteoglycan link protein 1	HAPLN1	CRT1, CRTL1	Homo_sapiens	Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.

Domains

Gene Ontology

PF00193 (2_Xlink) PF07686 (V-set)

GO:0005540 (enables) hyaluronic acid binding GO:0030021 (enables) extracellular matrix structural constituent conferring compression resistance GO:0001501 (involved in) skeletal system development GO:0007155 (involved in) cell adhesion GO:0007417 (involved in) central nervous system development GO:0031012 (is active in) extracellular matrix GO:0005576 (located in) extracellular region GO:0045202 (located in) synapse GO:0062023 (located in) collagen-containing extracellular matrix

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P10915|HPLN1_HUMAN Hyaluronan and proteoglycan link protein 1 OS=Homo sapiens OX=9606 GN=HAPLN1 PE=2 SV=2 MKSLLLLVLISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLP CKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDS DASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQA CLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF WDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILG YDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN >tr|E7FBW8|E7FBW8_DANRE Hyaluronan and proteoglycan link protein 1b OS=Danio rerio OX=7955 GN=hapln1b PE=4 SV=1 MTFLLLFLLVLSESRADNFEEAYSDLETYRTIYISENGPRLSVDTAQPKVISQRGGNATL PCKFNRDSSLPPNPKLRIKWTKLTSDYLKEIDVFVAMGFHKKSYGRFHGRVHLQAASESD ATLVITEITLEDYGKYKCEVIDGLEDDTAVVSLDLQGIVFPYFPRLGRYNLNFLEAEKAC RDQDAIVASFEQLYDAWRDGLDWCNAGWLSDGSVQYPITKPREPCGGKNTIPGVRNYGIR DKQKEQYDVFCFTSNYKGRFYYLIHSSKLTYDEAVQACQKDGAQIAKVGQMYAAWKLLGY DRCDAGWLADGSVRYPISKPRRRCSPTEAAVRFSGFPDKKHKLYGVYCYKSNN >tr|Q1LXE1|Q1LXE1_DANRE Hyaluronan and proteoglycan link protein 1a OS=Danio rerio OX=7955 GN=hapln1a PE=1 SV=1 MIALFSVALMVFASSLHVEAQDSESRVKVYANRGDNITLPCRLDGQSTLFGNRIKWTKIE DDSTETDVLISMGFHKKAYGSYQDRAYLLEVDDSDATLVITDLDVNDYGTYRCEFIDGMN DMTLEVDLEVQGKDSLSFTGVVFPYSPRLGRYNLNFQNAVAACQEQDAVVASFEQLYGEW KSGLDWCNAGWLSDGTVQYPITKPREPCGGARATAGLRNYGQRDKSNSRYDVFCFTAGLK GRFYYMIQPKKLNFDEAVDACKGDGAEIAKVGHMFAAWKLQGYDRCDAGWLADGSVRYPI SRPRKNCSPTEAAVRFVGFPDKKQKLYGVYCYKAQQ
Selected proteins from model organisms >sp|P10915|HPLN1_HUMAN Hyaluronan and proteoglycan link protein 1 OS=Homo sapiens OX=9606 GN=HAPLN1 PE=2 SV=2 MKSLLLLVLISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLP CKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDS DASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQA CLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF WDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILG YDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN >tr|E7FBW8|E7FBW8_DANRE Hyaluronan and proteoglycan link protein 1b OS=Danio rerio OX=7955 GN=hapln1b PE=4 SV=1 MTFLLLFLLVLSESRADNFEEAYSDLETYRTIYISENGPRLSVDTAQPKVISQRGGNATL PCKFNRDSSLPPNPKLRIKWTKLTSDYLKEIDVFVAMGFHKKSYGRFHGRVHLQAASESD ATLVITEITLEDYGKYKCEVIDGLEDDTAVVSLDLQGIVFPYFPRLGRYNLNFLEAEKAC RDQDAIVASFEQLYDAWRDGLDWCNAGWLSDGSVQYPITKPREPCGGKNTIPGVRNYGIR DKQKEQYDVFCFTSNYKGRFYYLIHSSKLTYDEAVQACQKDGAQIAKVGQMYAAWKLLGY DRCDAGWLADGSVRYPISKPRRRCSPTEAAVRFSGFPDKKHKLYGVYCYKSNN >tr|Q1LXE1|Q1LXE1_DANRE Hyaluronan and proteoglycan link protein 1a OS=Danio rerio OX=7955 GN=hapln1a PE=1 SV=1 MIALFSVALMVFASSLHVEAQDSESRVKVYANRGDNITLPCRLDGQSTLFGNRIKWTKIE DDSTETDVLISMGFHKKAYGSYQDRAYLLEVDDSDATLVITDLDVNDYGTYRCEFIDGMN DMTLEVDLEVQGKDSLSFTGVVFPYSPRLGRYNLNFQNAVAACQEQDAVVASFEQLYGEW KSGLDWCNAGWLSDGTVQYPITKPREPCGGARATAGLRNYGQRDKSNSRYDVFCFTAGLK GRFYYMIQPKKLNFDEAVDACKGDGAEIAKVGHMFAAWKLQGYDRCDAGWLADGSVRYPI SRPRKNCSPTEAAVRFVGFPDKKQKLYGVYCYKAQQ >NP_038528.3 hyaluronan and proteoglycan link protein 1 precursor [Mus musculus] MRSLLLLVLISVCWADHHLSDSYTPPDQDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPT AFGSGIHKIRIKWTKLTSDYLREVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLVITDLTLEDYGRYK CEVIEGLEDDTAVVALELQGVVFPYFPRLGRYNLNFHEARQACLDQDAVIASFDQLYDAWRGGLDWCNAG WLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQA CLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVY CFRAYN >XP_043320652.1 hyaluronan and proteoglycan link protein 1 isoform X1 [Cervus canadensis] MKKIIWATKMKSLLLLVLISICWADHPDNYTVDHDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGS GTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVV ALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTV PGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADG SVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCFRAYN >KAB0363570.1 hypothetical protein FD754_007726 [Muntiacus muntjak] MRGYVHPGVLTALSHFQSLHILKRAHQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTS DYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPR LGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKS RYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCS PSEAAVRFVGFPDKKHKLYGVYCFRAYN >KAB0387446.1 hypothetical protein FD755_002402 [Muntiacus reevesi] MRGYVHPGVLIALSHFQSLHILKRAHQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTS DYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPR LGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKS RYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCS PSEAAVRFVGFPDKKHKLYGVYCFRAYN >OWK12308.1 HAPLN1 [Cervus elaphus hippelaphus] MGVVIEDIAAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKT YGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQ DAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYL IHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKL YGVYCFRAYN >XP_005515977.1 hyaluronan and proteoglycan link protein 1 isoform X1 [Columba livia] MKSLLFLVLISACWAEPHPNNSSLEHERIIHIQAENGPRLLVVAEQAKIFSHRGGNVTLPCKFYHEHTSTAGSGTHKIRV KWTKLTSDYLKEVDVFVAMGHHRKSYGNYQGRVFLRESSENDASLVITNIMLEDYGRYKCEVIEGLEDDTAVVALNLEGV VFPYSPRLGRYNLNFHEAQRACLDQDSVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGKNTVPGVRNYG FWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLKDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPIS RPRKRCSPNEAAVRFVGFPDKKHKLYGVYCFRAYI >XP_018099885.1 hyaluronan and proteoglycan link protein 1 [Xenopus laevis] MKSLLCLVLIPLCWAAHHGNSTVYLDRIIHIHENGPRLVVEVEQTKVITHRGGNATLPCKFQHESITAGSPSHKIRIKWT KLTSDYLKEIDVFVSMGHHKRTYGSYQGRVYLQGASENDASLVITDITLEDYGRYKCEVIEGLEDDTAVISLDLQGVVYP FFPRMGRYNLNFHEAQQACQDQDAIIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITNPREPCGGKHTVPGVRNYGYRD KDKGRYDVFCFTSNFKGRFYYLIHPTKLTYDEAVQACINDGAQIAKVGQMYAAWKLLAYDRCDGGWLADGSVRYPISRPR RRCSPNEAAVRFVGFPDKKHKLYGVYCYKA >XP_030290935.1 hyaluronan and proteoglycan link protein 1-like [Sparus aurata] MIPVLICALISLSVAENNDLDTLFPELEHSRTIYVTENGPRLSVVADQLKVVTRRGGNVTLPCTIQRDQSMAPNRKMRIK WTKLTSDYLKEVDVFVAMDYHKRSYGTFHGRVHLQGSSPMDASLVITEITLEDYGRYKCEVIDGLEDGTVVVSLDLEGVV FPYYPRLGRYNLNFYDAERACHDQDAIVASFDQLYDAWRGNMDWCNAGWLSDGTVQYPITNPREPCGGKNMVPGIRNYGL RDKDKNHYDVFCFTSYYKGRFYYLIHPSKLTYDEAVRACQKDGAQIAKVGQMYAAWKLLGYDRCDAGWLADGSVRYPISH PRRRCSPTEAAVRFNGFPDKKHKLYGVYCFKGHN >XP_023816569.1 hyaluronan and proteoglycan link protein 1 isoform X1 [Oryzias latipes] MIPALICALVSVSVAENALDVLYPDLEFSRTIYVTEDGPRLTLVAEQSKVVSRRGGNVTLPCKIQRDQSLAPSRKMRIKW TKLTSDYLKEEDVFVAMDYNKKSFGSYHGRVHLQSSSPMECSLVITDITLEDYGKYKCEVIDGLEDGTVVVSLDLEGVIF PYFPRLGRYNLNFYDAERACRDQDAVVASFDQLYDAWRGGMDWCNAGWLSDGTVQYPITTPREPCGGKDTTPGIRNYGLR DKDKGHYDVFCFTSYHKGRFYYLIHPSKLTYDEAVRACQKDGAQIAKVGQMFAAWKLLGYDRCDAGWLADGSVRYPISRP RRRCSPTEAAVRFHGFPDKKHKLYGVYCFKGNN >XP_015829432.1 PREDICTED: hyaluronan and proteoglycan link protein 1 [Nothobranchius furzeri] MIPVLICALVSLSVAQHDLDILYPDLEHSRTIYVIEDGPRLSVVAEQSKVVSRRGGNVTLPCKIQRDQSLAPNHKMRIKW TKLTSDYLKELDVFVAMEHHKRSYGSFHRRVHLQGSSPTDASLVITELRLDDYGSYKCEVIDGLEDGTAVVSLDLEGVVF PYFPRLGRYNLNFYDADRACREQDAILASADQLYEAFQEGMNWCNAGWLSDGSVRYPITTPREPCGGKNMAPGVRTYGLR DKDKNHYDAFCFSSHYNGRFYYLIHPSKLTYDEAVSACQKDGAEIAKVGQMFVAWKLKGYDRCDPGWLADGSVRYPISNP KRRCSPTEAAVRFNGFPNKKHKLYGVYCFKGQN >XP_010723327.1 hyaluronan and proteoglycan link protein 4 [Meleagris gallopavo] MLMALLSLLSPQMCPQGPWAALLLLVGVLASDTPPNARGRKKVVHVLEGDSGAVVVQTAPGKVVTHRGGTIILPCRYHYD VSAHDPDEIRLKWTKVTEPMAFVDVFVALGKARRAFGSYRGRTALQEDGFGDASLIIRNVTLQDYGRYECEVTNELEDDT GMVKLDLEGVIFPYHPRLGRYTLNFHEAQQACLQQDGILASHDQLHQAWLEGMDWCNAGWLQDGSVQYPISHPREECGRK DTPVGVRNYGYRHKESEHYDAFCFTSNLNGKVYFLKTFRKLSYTEAVQACKNNGAAVAKVGQLYAAWKIQLLDRCEAGWL EDGSIRYPIVNPRARCGGREPGVRNLGFPDKKYKLFGVYCFKKAGDAPPEKKKGEGHPNRV >NP_062062.2 hyaluronan and proteoglycan link protein 1 precursor [Rattus norvegicus] MRSLLFLVLISVCRADHLSDSYTPDQDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAF GSGIHKIRIKWTKLTSDYLREVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLIITDLTLEDYGRYKCE VIEGLEDDTAVVALELQGVVFPYFPRLGRYNLNFHEACQACLDQDAVIASFDQLYDAWRGGLDWCNAGWL SDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL NDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCF RAYN >NP_776713.1 hyaluronan and proteoglycan link protein 1 precursor [Bos taurus] MKSLLLLVLISFCWADHHSDNYTVDHDRVIHIQAENGPRLLVEAEQAKVFSRRGGNVTLPCKFYRDPTAF GSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCE VIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWL SDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL NDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCF RAYN >NP_990813.1 hyaluronan and proteoglycan link protein 1 precursor [Gallus gallus] MTSLLFLVLISVCWAEPHPDNSSLEHERIIHIQEENGPRLLVVAEQAKIFSQRGGNVTLPCKFYHEHTST AGSGTHKIRVKWTKLTSDYLKEVDVFVAMGHHRKSYGKYQGRVFLRESSENDASLIITNIMLEDYGRYKC EVIEGLEDDTAVVALNLEGVVFPYSPRLGRYNLNFHEAQQACLDQDSIIASFDQLYEAWRSGLDWCNAGW LSDGSVQYPITKPREPCGGKNTVPGVRNYGFWDKERSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQAC LKDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRKRCSPNEAAVRFVGFPDKKHKLYGVYC FRAYN >NP_001004028.1 hyaluronan and proteoglycan link protein 1 precursor [Sus scrofa] MKSLLLLVLISVCWADHLSNNYTLDHDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFFRDPTAF GSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCE VIEGLEDDTAVVALDLEGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWL SDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL NDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCRPNEAAVRFVGFPDKKHKLYGVYCF RAYN >XP_001147083.1 hyaluronan and proteoglycan link protein 1 [Pan troglodytes] MKSLLLLVLISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAF GSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCE VIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWL SDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL NDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTESAVRFVGFPDKKHKLYGVYCF RAYN >XP_849484.1 hyaluronan and proteoglycan link protein 1 [Canis lupus familiaris] MKSLLLLVLISICWADHHSDNYTLNYDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAF GSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHRKAYGGYQGRVFLKGGSENDASLVIADLTLEDYGKYKCE VIEGLEDDTAVVALELQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYEAWRGGLDWCNAGWL SDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL NDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCF RAYN >XP_002713942.1 PREDICTED: hyaluronan and proteoglycan link protein 1 isoform X1 [Oryctolagus cuniculus] MKSLLFLVLISICWADHQSNNYTLGHDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAF GSGIHKIRIKWTKLTSDYLREVDVFVSMGYHQKTYGGYQGRVFLKGGSENDASLVITGLTLEDYGRYKCE VIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLEQDAVIASFDQLYDAWRGGLDWCNAGWL SDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL NDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCF RAYN >XP_002815765.2 hyaluronan and proteoglycan link protein 1 [Pongo abelii] MKSLLLLVLISICWADHLSDNYTLDHDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAF GSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLVITDLTLEDYGRYKCE VIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAAIASFDQLYDAWRGGLDWCNAGWL SDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL NDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCF RAYN >XP_003822290.1 hyaluronan and proteoglycan link protein 1 [Pan paniscus] MKSLLLLVLISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAF GSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCE VIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWL SDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL NDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTESAVRFVGFPDKKHKLYGVYCF RAYN >XP_006927896.1 hyaluronan and proteoglycan link protein 1 isoform X1 [Felis catus] MMKSLLLLVLISICWADHHSDNYTLDHDRVIHIQAENGPRLLVEAEQTKVFSHRGGNVTLPCKFYRDPTA FGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKAYAGYQGRVFLKGGSDNDASLVIADLTLEDYGRYKC EVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGW LSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQAC LNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYC FRAYN >XP_004009120.1 hyaluronan and proteoglycan link protein 1 [Ovis aries] MKSLLLLVLISICWADHHSNNYTVDHDRVIHIQAENGPRLLVEAEQAKVFSRRGGNVTLPCKFYRDPTAF GSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCE VIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWL SDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL NDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCF RAYN >XP_018884172.1 hyaluronan and proteoglycan link protein 1 [Gorilla gorilla gorilla] MKSLLLLVLISICWADHLSDNYTLDHDRVIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAF GSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCE VIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWL SDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL NDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCF RAYN >XP_005683456.1 PREDICTED: hyaluronan and proteoglycan link protein 1 [Capra hircus] MKSLLLLVLISICWADHHSNNYTVDHDRVIHIQAENGPRLLVEAEQAKVFSRRGGNVTLPCKFYRDPTAF GSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCE VIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWL SDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL NDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCF RAYN >XP_006021303.1 hyaluronan and proteoglycan link protein 1 [Alligator sinensis] MKSLLFLVLISICCAEPHIGNYTLDHERIIHIQEDDGPRLSVVAEQSKVFSHRGGNVTLPCKFYRESISA GSGTHRIRVKWTKLTSDYLKEVDVFVAMGHHRKSYGNYQDRVFLKEGSSNDASLVITALTLEDYGKYKCE VIEGLEDDTAMVTLDLQGVVFPYFPWLGRYNLNFHEAQQACLDQDSVIASFDQLYEAWRSGLDWCNAGWL SDGSVQYPITKPREPCGGKNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIQPTKLTYDEAVQACL KDGSQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRKRCSPNEAAVRFVGFPDKKHKLYGVYCF RSYN >XP_006270247.1 PREDICTED: hyaluronan and proteoglycan link protein 1 isoform X1 [Alligator mississippiensis] MKSLLFLVLISICCAEPHIGNYTLDHERIIHIQEDDGPRLSVVAEQSKVFSHRGGNITLPCKFYRESISA GSGTHRIRVKWTKLTSDYLKEVDVFVAMGHHRKSYGNYQDRVFLKEGSSNDASLVITAVTLEDYGKYKCE VIEGLEDDTAMVTLDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDSVIASFDQLYEAWRSGLDWCNAGWL SDGSVQYPITKPREPCGGKNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL KDGSQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRKRCSPNEAAVRFVGFPDKKHKLYGVYCF RAYN >XP_020749849.1 hyaluronan and proteoglycan link protein 1 [Odocoileus virginianus texanus] MKSLLLLVLISICWADHHPGNYTVDHDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAF GSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCE VIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWL SDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACL NDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCF RAYN >XP_040197640.1 hyaluronan and proteoglycan link protein 1 [Rana temporaria] MKRVLFLVLISFCWADHHGSNSPVYNDRIIHVHENGPRLVVEVDQTKVISHRGGNATLPCKFHHESVSAG SLSHKIRIKWTKLTSDYLKEVDVFVSMGHHKKSYGSYQGRVYLQGSSANDASLVITDITLEDYGRYKCEV IEGLEDDTAVVSLDLQGIVFPFFPRLGRYNLNFNEAQQACQDQDSIIASFDQLYDGWRSGLDWCNAGWLS DGSVQYPITNPREQCGGKNIVPGVRNYGYRDKDKGRYDVFCFTSNFKGRFYYLIHPVKLTYDEAIQACIN DGAQIAKVGQMYAAWKLLGYDRCDGGWLADGSVRYPISKPRRRCSPNEAAVRFVGYPDKKHKLYGVYCYK A >XP_031573871.1 stabilin-1-like [Actinia tenebrosa] MNEGTYHCNCSIQIPXLPYLDQHCAVDHSLMKKSGTFRNVFNLTIKLLRYALNYYEAERACAIFGAQXSSLTQLDDAWKA GFDSCRYGWLVDGTVRFPIIYPRQGCSSSPPSIRGSTTPQDKWNSRHDVYCYRETDNCNDGKDWHQNRQACYKFFLDTKA RQTPAAQTCALEGGILGVFNSKAKLIFLQDYLQRRSIADQQILVGLSQDAGGAWKWTNGEAVRSSLWNXTQPTGPIGTVN XAXKALDNVPDSDEWKLPFVCQKPVP
Mafft alignment of selected proteins >sp|P10915|HPLN1_HUMAN Hyaluronan and proteoglycan link protein 1 OS=Homo sapiens OX=9606 GN=HAPLN1 PE=2 SV=2 ---------MKSLL------------LLVLISICWADHL-SDNY-T-LDHDRAIHI---- -QAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGIHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTV VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KILGYDRCDAG----WLADGSVRYPISRPRRRCSP----TEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >tr|E7FBW8|E7FBW8_DANRE Hyaluronan and proteoglycan link protein 1b OS=Danio rerio OX=7955 GN=hapln1b PE=4 SV=1 M--------TFLLL------------FLLVLSESRADN--FEEAYSDLETYRTIYI---- --SENGPRLSVDTAQPKVISQRGGNATLPCKFNRDSSL---PPNPKLRIKWTKLTSDYLK EIDVFVAMGFHKKSYGRFHGRVHLQAASESDATLVITEITLEDYGKYKCEVIDGLEDDTA VVSLDLQ--------GIVFPYFPRLGRYNLNFLEAEKACRDQDAIVASFEQLYDAWRDGL DWCNAGWLSDGSVQYPITKPREPCGGKNTIPGVRNYGI-RDKQKEQYDVFCF--TSNYKG ---------RFYYLIHSSKLTYDEAVQACQKDGAQIA----KVGQMY----------AAW KLLGYDRCDAG----WLADGSVRYPISKPRRRCSP----TEAAVRFSGFPDKKHKLYGVY CYKSNN---------------- >tr|Q1LXE1|Q1LXE1_DANRE Hyaluronan and proteoglycan link protein 1a OS=Danio rerio OX=7955 GN=hapln1a PE=1 SV=1 --------------------------MIALFSVAL------------MVFASSLHV---- -EAQDS------ESRVKVYANRGDNITLPCRLDGQSTL---FGN---RIKWTKIEDDS-T ETDVLISMGFHKKAYGSYQDRAYLLEVDDSDATLVITDLDVNDYGTYRCEFIDGMNDMTL EVDLEVQGKDSLSFTGVVFPYSPRLGRYNLNFQNAVAACQEQDAVVASFEQLYGEWKSGL DWCNAGWLSDGTVQYPITKPREPCGGARATAGLRNYGQ-RDKSNSRYDVFCF--TAGLKG ---------RFYYMIQPKKLNFDEAVDACKGDGAEIA----KVGHMF----------AAW KLQGYDRCDAG----WLADGSVRYPISRPRKNCSP----TEAAVRFVGFPDKKQKLYGVY CYKAQQ---------------- >NP_038528.3 hyaluronan and proteoglycan link protein 1 precursor [Mus musculus] ---------MRSLL------------LLVLISVCWADHHLSDSY-TPPDQDRVIHI---- -QAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGIHKIRIKWTKLTSDYLR EVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALELQ--------GVVFPYFPRLGRYNLNFHEARQACLDQDAVIASFDQLYDAWRGGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----TEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_043320652.1 hyaluronan and proteoglycan link protein 1 isoform X1 [Cervus canadensis] MKKIIWATKMKSLL------------LLVLISICWAD-H-PDNY-T-VDHDRVIHI---- -QAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGTHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----SEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >KAB0363570.1 hypothetical protein FD754_007726 [Muntiacus muntjak] ---------MRGYV------------------------H-PGVLTA-LSHFQSLHILKRA HQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGTHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----SEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >KAB0387446.1 hypothetical protein FD755_002402 [Muntiacus reevesi] ---------MRGYV------------------------H-PGVLIA-LSHFQSLHILKRA HQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGTHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----SEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >OWK12308.1 HAPLN1 [Cervus elaphus hippelaphus] ------------------------------MGVVIED------------------I---- -AAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGTHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----SEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_005515977.1 hyaluronan and proteoglycan link protein 1 isoform X1 [Columba livia] ---------MKSLL------------FLVLISACWAEPH-PNNS-S-LEHERIIHI---- -QAENGPRLLVVAEQAKIFSHRGGNVTLPCKFYHEHTSTAGSGTHKIRVKWTKLTSDYLK EVDVFVAMGHHRKSYGNYQGRVFLRESSENDASLVITNIMLEDYGRYKCEVIEGLEDDTA VVALNLE--------GVVFPYSPRLGRYNLNFHEAQRACLDQDSVIASFDQLYDAWRSGL DWCNAGWLSDGSVQYPITKPREPCGGKNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLKDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRKRCSP----NEAAVRFVGFPDKKHKLYGVY CFRAYI---------------- >XP_018099885.1 hyaluronan and proteoglycan link protein 1 [Xenopus laevis] ---------MKSLL------------CLVLIPLCWAAHH--GNS-T-VYLDRIIHI---- --HENGPRLVVEVEQTKVITHRGGNATLPCKFQHESIT-AGSPSHKIRIKWTKLTSDYLK EIDVFVSMGHHKRTYGSYQGRVYLQGASENDASLVITDITLEDYGRYKCEVIEGLEDDTA VISLDLQ--------GVVYPFFPRMGRYNLNFHEAQQACQDQDAIIASFDQLYDAWRSGL DWCNAGWLSDGSVQYPITNPREPCGGKHTVPGVRNYGY-RDKDKGRYDVFCF--TSNFKG ---------RFYYLIHPTKLTYDEAVQACINDGAQIA----KVGQMY----------AAW KLLAYDRCDGG----WLADGSVRYPISRPRRRCSP----NEAAVRFVGFPDKKHKLYGVY CYKA------------------ >XP_030290935.1 hyaluronan and proteoglycan link protein 1-like [Sparus aurata] ---------MIPVL------------ICALISLSVAENNDLDTLFPELEHSRTIYV---- --TENGPRLSVVADQLKVVTRRGGNVTLPCTIQRDQSM---APNRKMRIKWTKLTSDYLK EVDVFVAMDYHKRSYGTFHGRVHLQGSSPMDASLVITEITLEDYGRYKCEVIDGLEDGTV VVSLDLE--------GVVFPYYPRLGRYNLNFYDAERACHDQDAIVASFDQLYDAWRGNM DWCNAGWLSDGTVQYPITNPREPCGGKNMVPGIRNYGL-RDKDKNHYDVFCF--TSYYKG ---------RFYYLIHPSKLTYDEAVRACQKDGAQIA----KVGQMY----------AAW KLLGYDRCDAG----WLADGSVRYPISHPRRRCSP----TEAAVRFNGFPDKKHKLYGVY CFKGHN---------------- >XP_023816569.1 hyaluronan and proteoglycan link protein 1 isoform X1 [Oryzias latipes] ---------MIPAL------------ICALVSVSVAENA-LDVLYPDLEFSRTIYV---- --TEDGPRLTLVAEQSKVVSRRGGNVTLPCKIQRDQSL---APSRKMRIKWTKLTSDYLK EEDVFVAMDYNKKSFGSYHGRVHLQSSSPMECSLVITDITLEDYGKYKCEVIDGLEDGTV VVSLDLE--------GVIFPYFPRLGRYNLNFYDAERACRDQDAVVASFDQLYDAWRGGM DWCNAGWLSDGTVQYPITTPREPCGGKDTTPGIRNYGL-RDKDKGHYDVFCF--TSYHKG ---------RFYYLIHPSKLTYDEAVRACQKDGAQIA----KVGQMF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----TEAAVRFHGFPDKKHKLYGVY CFKGNN---------------- >XP_015829432.1 PREDICTED: hyaluronan and proteoglycan link protein 1 [Nothobranchius furzeri] ---------MIPVL------------ICALVSLSVAQHD-LDILYPDLEHSRTIYV---- --IEDGPRLSVVAEQSKVVSRRGGNVTLPCKIQRDQSL---APNHKMRIKWTKLTSDYLK ELDVFVAMEHHKRSYGSFHRRVHLQGSSPTDASLVITELRLDDYGSYKCEVIDGLEDGTA VVSLDLE--------GVVFPYFPRLGRYNLNFYDADRACREQDAILASADQLYEAFQEGM NWCNAGWLSDGSVRYPITTPREPCGGKNMAPGVRTYGL-RDKDKNHYDAFCF--SSHYNG ---------RFYYLIHPSKLTYDEAVSACQKDGAEIA----KVGQMF----------VAW KLKGYDRCDPG----WLADGSVRYPISNPKRRCSP----TEAAVRFNGFPNKKHKLYGVY CFKGQN---------------- >XP_010723327.1 hyaluronan and proteoglycan link protein 4 [Meleagris gallopavo] MLMA-----LLSLLSPQMCPQGPWAALLLLVGVLASDTP-PNA----RGRKKVVHV---- -LEGDSGAVVVQTAPGKVVTHRGGTIILPCRYHYDVSA---HDPDEIRLKWTKVT-EPMA FVDVFVALGKARRAFGSYRGRTALQEDGFGDASLIIRNVTLQDYGRYECEVTNELEDDTG MVKLDLE--------GVIFPYHPRLGRYTLNFHEAQQACLQQDGILASHDQLHQAWLEGM DWCNAGWLQDGSVQYPISHPREECGRKDTPVGVRNYGY-RHKESEHYDAFCF--TSNLNG ---------KVYFLKTFRKLSYTEAVQACKNNGAAVA----KVGQLY----------AAW KIQLLDRCEAG----WLEDGSIRYPIVNPRARCGG----REPGVRNLGFPDKKYKLFGVY CFKKAGDAPPEKKKGEGHPNRV >NP_062062.2 hyaluronan and proteoglycan link protein 1 precursor [Rattus norvegicus] ---------MRSLL------------FLVLISVCRADHL-SDSY-T-PDQDRVIHI---- -QAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGIHKIRIKWTKLTSDYLR EVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLIITDLTLEDYGRYKCEVIEGLEDDTA VVALELQ--------GVVFPYFPRLGRYNLNFHEACQACLDQDAVIASFDQLYDAWRGGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----TEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >NP_776713.1 hyaluronan and proteoglycan link protein 1 precursor [Bos taurus] ---------MKSLL------------LLVLISFCWADHH-SDNY-T-VDHDRVIHI---- -QAENGPRLLVEAEQAKVFSRRGGNVTLPCKFYRDPTA-FGSGTHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----SEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >NP_990813.1 hyaluronan and proteoglycan link protein 1 precursor [Gallus gallus] ---------MTSLL------------FLVLISVCWAEPH-PDNS-S-LEHERIIHI---- -QEENGPRLLVVAEQAKIFSQRGGNVTLPCKFYHEHTSTAGSGTHKIRVKWTKLTSDYLK EVDVFVAMGHHRKSYGKYQGRVFLRESSENDASLIITNIMLEDYGRYKCEVIEGLEDDTA VVALNLE--------GVVFPYSPRLGRYNLNFHEAQQACLDQDSIIASFDQLYEAWRSGL DWCNAGWLSDGSVQYPITKPREPCGGKNTVPGVRNYGF-WDKERSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLKDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRKRCSP----NEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >NP_001004028.1 hyaluronan and proteoglycan link protein 1 precursor [Sus scrofa] ---------MKSLL------------LLVLISVCWADHL-SNNY-T-LDHDRVIHI---- -QAENGPRLLVEAEQAKVFSHRGGNVTLPCKFFRDPTA-FGSGTHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLE--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCRP----NEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_001147083.1 hyaluronan and proteoglycan link protein 1 [Pan troglodytes] ---------MKSLL------------LLVLISICWADHL-SDNY-T-LDHDRAIHI---- -QAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGIHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KILGYDRCDAG----WLADGSVRYPISRPRRRCSP----TESAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_849484.1 hyaluronan and proteoglycan link protein 1 [Canis lupus familiaris] ---------MKSLL------------LLVLISICWADHH-SDNY-T-LNYDRVIHI---- -QAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGTHKIRIKWTKLTSDYLK EVDVFVSMGYHRKAYGGYQGRVFLKGGSENDASLVIADLTLEDYGKYKCEVIEGLEDDTA VVALELQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYEAWRGGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----TEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_002713942.1 PREDICTED: hyaluronan and proteoglycan link protein 1 isoform X1 [Oryctolagus cuniculus] ---------MKSLL------------FLVLISICWADHQ-SNNY-T-LGHDRVIHI---- -QAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGIHKIRIKWTKLTSDYLR EVDVFVSMGYHQKTYGGYQGRVFLKGGSENDASLVITGLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLEQDAVIASFDQLYDAWRGGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----TEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_002815765.2 hyaluronan and proteoglycan link protein 1 [Pongo abelii] ---------MKSLL------------LLVLISICWADHL-SDNY-T-LDHDRVIHI---- -QAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGIHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAAIASFDQLYDAWRGGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KILGYDRCDAG----WLADGSVRYPISRPRRRCSP----TEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_003822290.1 hyaluronan and proteoglycan link protein 1 [Pan paniscus] ---------MKSLL------------LLVLISICWADHL-SDNY-T-LDHDRAIHI---- -QAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGIHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KILGYDRCDAG----WLADGSVRYPISRPRRRCSP----TESAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_006927896.1 hyaluronan and proteoglycan link protein 1 isoform X1 [Felis catus] M--------MKSLL------------LLVLISICWADHH-SDNY-T-LDHDRVIHI---- -QAENGPRLLVEAEQTKVFSHRGGNVTLPCKFYRDPTA-FGSGTHKIRIKWTKLTSDYLK EVDVFVSMGYHKKAYAGYQGRVFLKGGSDNDASLVIADLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----TEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_004009120.1 hyaluronan and proteoglycan link protein 1 [Ovis aries] ---------MKSLL------------LLVLISICWADHH-SNNY-T-VDHDRVIHI---- -QAENGPRLLVEAEQAKVFSRRGGNVTLPCKFYRDPTA-FGSGTHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----SEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_018884172.1 hyaluronan and proteoglycan link protein 1 [Gorilla gorilla gorilla] ---------MKSLL------------LLVLISICWADHL-SDNY-T-LDHDRVIHI---- -QAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGIHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KILGYDRCDAG----WLADGSVRYPISRPRRRCSP----TEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_005683456.1 PREDICTED: hyaluronan and proteoglycan link protein 1 [Capra hircus] ---------MKSLL------------LLVLISICWADHH-SNNY-T-VDHDRVIHI---- -QAENGPRLLVEAEQAKVFSRRGGNVTLPCKFYRDPTA-FGSGTHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----SEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_006021303.1 hyaluronan and proteoglycan link protein 1 [Alligator sinensis] ---------MKSLL------------FLVLISICCAEPH-IGNY-T-LDHERIIHI---- -QEDDGPRLSVVAEQSKVFSHRGGNVTLPCKFYRESIS-AGSGTHRIRVKWTKLTSDYLK EVDVFVAMGHHRKSYGNYQDRVFLKEGSSNDASLVITALTLEDYGKYKCEVIEGLEDDTA MVTLDLQ--------GVVFPYFPWLGRYNLNFHEAQQACLDQDSVIASFDQLYEAWRSGL DWCNAGWLSDGSVQYPITKPREPCGGKNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIQPTKLTYDEAVQACLKDGSQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRKRCSP----NEAAVRFVGFPDKKHKLYGVY CFRSYN---------------- >XP_006270247.1 PREDICTED: hyaluronan and proteoglycan link protein 1 isoform X1 [Alligator mississippiensis] ---------MKSLL------------FLVLISICCAEPH-IGNY-T-LDHERIIHI---- -QEDDGPRLSVVAEQSKVFSHRGGNITLPCKFYRESIS-AGSGTHRIRVKWTKLTSDYLK EVDVFVAMGHHRKSYGNYQDRVFLKEGSSNDASLVITAVTLEDYGKYKCEVIEGLEDDTA MVTLDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDSVIASFDQLYEAWRSGL DWCNAGWLSDGSVQYPITKPREPCGGKNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLKDGSQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRKRCSP----NEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_020749849.1 hyaluronan and proteoglycan link protein 1 [Odocoileus virginianus texanus] ---------MKSLL------------LLVLISICWADHH-PGNY-T-VDHDRVIHI---- -QAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTA-FGSGTHKIRIKWTKLTSDYLK EVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTA VVALDLQ--------GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGL DWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF-WDKDKSRYDVFCF--TSNFNG ---------RFYYLIHPTKLTYDEAVQACLNDGAQIA----KVGQIF----------AAW KLLGYDRCDAG----WLADGSVRYPISRPRRRCSP----SEAAVRFVGFPDKKHKLYGVY CFRAYN---------------- >XP_040197640.1 hyaluronan and proteoglycan link protein 1 [Rana temporaria] ---------MKRVL------------FLVLISFCWADHH-GSNS-P-VYNDRIIHV---- --HENGPRLVVEVDQTKVISHRGGNATLPCKFHHESVS-AGSLSHKIRIKWTKLTSDYLK EVDVFVSMGHHKKSYGSYQGRVYLQGSSANDASLVITDITLEDYGRYKCEVIEGLEDDTA VVSLDLQ--------GIVFPFFPRLGRYNLNFNEAQQACQDQDSIIASFDQLYDGWRSGL DWCNAGWLSDGSVQYPITNPREQCGGKNIVPGVRNYGY-RDKDKGRYDVFCF--TSNFKG ---------RFYYLIHPVKLTYDEAIQACINDGAQIA----KVGQMY----------AAW KLLGYDRCDGG----WLADGSVRYPISKPRRRCSP----NEAAVRFVGYPDKKHKLYGVY CYKA------------------ >XP_031573871.1 stabilin-1-like [Actinia tenebrosa] ------------------------------------------------------------ ------------------------------------------------------------ ------------MNEGTYHCNCSIQ-------------IPXLPYLDQHCAVDHSLMKKSG TF-------------RNVFNLTIKLLRYALNYYEAERACAIFGAQXSSLTQLDDAWKAGF DSCRYGWLVDGTVRFPIIYPRQGC--SSSPPSIRGSTTPQDKWNSRHDVYCYRETDNCND GKDWHQNRQACYKFFLDTKARQTPAAQTCALEGGILGVFNSKAKLIFLQDYLQRRSIADQ QILVGLSQDAGGAWKWTNGEAVRSSLWNXTQPTGPIGTVNXAXKALDNVPDSDEWKLPFV CQKPVP----------------
BMGE Cleaned alignment of selected proteins >sp|P10915|HPLN1_HUMAN Hyaluronan and proteoglycan link protein 1 OS=Homo sapiens OX=9606 GN=HAPLN1 PE=2 SV=2 MKSLLLLVLISICWADHLLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN >tr|E7FBW8|E7FBW8_DANRE Hyaluronan and proteoglycan link protein 1b OS=Danio rerio OX=7955 GN=hapln1b PE=4 SV=1 TFLLLFLLVLSESRADN-LETYRTIYI-SENGPRLSVDTAQPKVISQRGGNATLPCKFNRDSSL--PPNPKLRIKWTKLTSDYLKEIDVFVAMGFHKKSYGRFHGRVHLQAASESDATLVITEITLEDYGKYKCEVIDGLEDDTAVVSLDLQGIVFPYFPRLGRYNLNFLEAEKACRDQDAIVASFEQLYDAWRDGLDWCNAGWLSDGSVQYPITKPREPCGGKNTIPGVRNYGIRDKQKEQYDVFCFTSNYKGRFYYLIHSSKLTYDEAVQACQKDGAQIAKVGQMYAAWKLLGYDRCDAGWLADGSVRYPISKPRRRCSPTEAAVRFSGFPDKKHKLYGVYCYKSNN >tr|Q1LXE1|Q1LXE1_DANRE Hyaluronan and proteoglycan link protein 1a OS=Danio rerio OX=7955 GN=hapln1a PE=1 SV=1 -----MIALFSVAL----MVFASSLHVEAQDS------ESRVKVYANRGDNITLPCRLDGQSTL--FGN---RIKWTKIEDDS-TETDVLISMGFHKKAYGSYQDRAYLLEVDDSDATLVITDLDVNDYGTYRCEFIDGMNDMTLEVDLEVQGVVFPYSPRLGRYNLNFQNAVAACQEQDAVVASFEQLYGEWKSGLDWCNAGWLSDGTVQYPITKPREPCGGARATAGLRNYGQRDKSNSRYDVFCFTAGLKGRFYYMIQPKKLNFDEAVDACKGDGAEIAKVGHMFAAWKLQGYDRCDAGWLADGSVRYPISRPRKNCSPTEAAVRFVGFPDKKQKLYGVYCYKAQQ >NP_038528.3 hyaluronan and proteoglycan link protein 1 precursor [Mus musculus] MRSLLLLVLISVCWADHHPDQDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLREVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALELQGVVFPYFPRLGRYNLNFHEARQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN >XP_043320652.1 hyaluronan and proteoglycan link protein 1 isoform X1 [Cervus canadensis] MKSLLLLVLISICWAD-HVDHDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCFRAYN >KAB0363570.1 hypothetical protein FD754_007726 [Muntiacus muntjak] MRGYV------------HLSHFQSLHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCFRAYN >KAB0387446.1 hypothetical protein FD755_002402 [Muntiacus reevesi] MRGYV------------HLSHFQSLHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCFRAYN >OWK12308.1 HAPLN1 [Cervus elaphus hippelaphus] ---------MGVVIED----------IAAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCFRAYN >XP_005515977.1 hyaluronan and proteoglycan link protein 1 isoform X1 [Columba livia] MKSLLFLVLISACWAEPHLEHERIIHIQAENGPRLLVVAEQAKIFSHRGGNVTLPCKFYHEHTSAGSGTHKIRVKWTKLTSDYLKEVDVFVAMGHHRKSYGNYQGRVFLRESSENDASLVITNIMLEDYGRYKCEVIEGLEDDTAVVALNLEGVVFPYSPRLGRYNLNFHEAQRACLDQDSVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGKNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLKDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRKRCSPNEAAVRFVGFPDKKHKLYGVYCFRAYI >XP_018099885.1 hyaluronan and proteoglycan link protein 1 [Xenopus laevis] MKSLLCLVLIPLCWAAHHVYLDRIIHI-HENGPRLVVEVEQTKVITHRGGNATLPCKFQHESITAGSPSHKIRIKWTKLTSDYLKEIDVFVSMGHHKRTYGSYQGRVYLQGASENDASLVITDITLEDYGRYKCEVIEGLEDDTAVISLDLQGVVYPFFPRMGRYNLNFHEAQQACQDQDAIIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITNPREPCGGKHTVPGVRNYGYRDKDKGRYDVFCFTSNFKGRFYYLIHPTKLTYDEAVQACINDGAQIAKVGQMYAAWKLLAYDRCDGGWLADGSVRYPISRPRRRCSPNEAAVRFVGFPDKKHKLYGVYCYKA-- >XP_030290935.1 hyaluronan and proteoglycan link protein 1-like [Sparus aurata] MIPVLICALISLSVAENNLEHSRTIYV-TENGPRLSVVADQLKVVTRRGGNVTLPCTIQRDQSM--APNRKMRIKWTKLTSDYLKEVDVFVAMDYHKRSYGTFHGRVHLQGSSPMDASLVITEITLEDYGRYKCEVIDGLEDGTVVVSLDLEGVVFPYYPRLGRYNLNFYDAERACHDQDAIVASFDQLYDAWRGNMDWCNAGWLSDGTVQYPITNPREPCGGKNMVPGIRNYGLRDKDKNHYDVFCFTSYYKGRFYYLIHPSKLTYDEAVRACQKDGAQIAKVGQMYAAWKLLGYDRCDAGWLADGSVRYPISHPRRRCSPTEAAVRFNGFPDKKHKLYGVYCFKGHN >XP_023816569.1 hyaluronan and proteoglycan link protein 1 isoform X1 [Oryzias latipes] MIPALICALVSVSVAENALEFSRTIYV-TEDGPRLTLVAEQSKVVSRRGGNVTLPCKIQRDQSL--APSRKMRIKWTKLTSDYLKEEDVFVAMDYNKKSFGSYHGRVHLQSSSPMECSLVITDITLEDYGKYKCEVIDGLEDGTVVVSLDLEGVIFPYFPRLGRYNLNFYDAERACRDQDAVVASFDQLYDAWRGGMDWCNAGWLSDGTVQYPITTPREPCGGKDTTPGIRNYGLRDKDKGHYDVFCFTSYHKGRFYYLIHPSKLTYDEAVRACQKDGAQIAKVGQMFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFHGFPDKKHKLYGVYCFKGNN >XP_015829432.1 PREDICTED: hyaluronan and proteoglycan link protein 1 [Nothobranchius furzeri] MIPVLICALVSLSVAQHDLEHSRTIYV-IEDGPRLSVVAEQSKVVSRRGGNVTLPCKIQRDQSL--APNHKMRIKWTKLTSDYLKELDVFVAMEHHKRSYGSFHRRVHLQGSSPTDASLVITELRLDDYGSYKCEVIDGLEDGTAVVSLDLEGVVFPYFPRLGRYNLNFYDADRACREQDAILASADQLYEAFQEGMNWCNAGWLSDGSVRYPITTPREPCGGKNMAPGVRTYGLRDKDKNHYDAFCFSSHYNGRFYYLIHPSKLTYDEAVSACQKDGAEIAKVGQMFVAWKLKGYDRCDPGWLADGSVRYPISNPKRRCSPTEAAVRFNGFPNKKHKLYGVYCFKGQN >XP_010723327.1 hyaluronan and proteoglycan link protein 4 [Meleagris gallopavo] LLSLLLLLLVGVLASDTPRGRKKVVHVLEGDSGAVVVQTAPGKVVTHRGGTIILPCRYHYDVSA--HDPDEIRLKWTKVT-EPMAFVDVFVALGKARRAFGSYRGRTALQEDGFGDASLIIRNVTLQDYGRYECEVTNELEDDTGMVKLDLEGVIFPYHPRLGRYTLNFHEAQQACLQQDGILASHDQLHQAWLEGMDWCNAGWLQDGSVQYPISHPREECGRKDTPVGVRNYGYRHKESEHYDAFCFTSNLNGKVYFLKTFRKLSYTEAVQACKNNGAAVAKVGQLYAAWKIQLLDRCEAGWLEDGSIRYPIVNPRARCGGREPGVRNLGFPDKKYKLFGVYCFKKAG >NP_062062.2 hyaluronan and proteoglycan link protein 1 precursor [Rattus norvegicus] MRSLLFLVLISVCRADHLPDQDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLREVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLIITDLTLEDYGRYKCEVIEGLEDDTAVVALELQGVVFPYFPRLGRYNLNFHEACQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN >NP_776713.1 hyaluronan and proteoglycan link protein 1 precursor [Bos taurus] MKSLLLLVLISFCWADHHVDHDRVIHIQAENGPRLLVEAEQAKVFSRRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCFRAYN >NP_990813.1 hyaluronan and proteoglycan link protein 1 precursor [Gallus gallus] MTSLLFLVLISVCWAEPHLEHERIIHIQEENGPRLLVVAEQAKIFSQRGGNVTLPCKFYHEHTSAGSGTHKIRVKWTKLTSDYLKEVDVFVAMGHHRKSYGKYQGRVFLRESSENDASLIITNIMLEDYGRYKCEVIEGLEDDTAVVALNLEGVVFPYSPRLGRYNLNFHEAQQACLDQDSIIASFDQLYEAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGKNTVPGVRNYGFWDKERSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLKDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRKRCSPNEAAVRFVGFPDKKHKLYGVYCFRAYN >NP_001004028.1 hyaluronan and proteoglycan link protein 1 precursor [Sus scrofa] MKSLLLLVLISVCWADHLLDHDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFFRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLEGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCRPNEAAVRFVGFPDKKHKLYGVYCFRAYN >XP_001147083.1 hyaluronan and proteoglycan link protein 1 [Pan troglodytes] MKSLLLLVLISICWADHLLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTESAVRFVGFPDKKHKLYGVYCFRAYN >XP_849484.1 hyaluronan and proteoglycan link protein 1 [Canis lupus familiaris] MKSLLLLVLISICWADHHLNYDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHRKAYGGYQGRVFLKGGSENDASLVIADLTLEDYGKYKCEVIEGLEDDTAVVALELQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYEAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN >XP_002713942.1 PREDICTED: hyaluronan and proteoglycan link protein 1 isoform X1 [Oryctolagus cuniculus] MKSLLFLVLISICWADHQLGHDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLREVDVFVSMGYHQKTYGGYQGRVFLKGGSENDASLVITGLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLEQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN >XP_002815765.2 hyaluronan and proteoglycan link protein 1 [Pongo abelii] MKSLLLLVLISICWADHLLDHDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAAIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN >XP_003822290.1 hyaluronan and proteoglycan link protein 1 [Pan paniscus] MKSLLLLVLISICWADHLLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTESAVRFVGFPDKKHKLYGVYCFRAYN >XP_006927896.1 hyaluronan and proteoglycan link protein 1 isoform X1 [Felis catus] MKSLLLLVLISICWADHHLDHDRVIHIQAENGPRLLVEAEQTKVFSHRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKAYAGYQGRVFLKGGSDNDASLVIADLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN >XP_004009120.1 hyaluronan and proteoglycan link protein 1 [Ovis aries] MKSLLLLVLISICWADHHVDHDRVIHIQAENGPRLLVEAEQAKVFSRRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCFRAYN >XP_018884172.1 hyaluronan and proteoglycan link protein 1 [Gorilla gorilla gorilla] MKSLLLLVLISICWADHLLDHDRVIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDSDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN >XP_005683456.1 PREDICTED: hyaluronan and proteoglycan link protein 1 [Capra hircus] MKSLLLLVLISICWADHHVDHDRVIHIQAENGPRLLVEAEQAKVFSRRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCFRAYN >XP_006021303.1 hyaluronan and proteoglycan link protein 1 [Alligator sinensis] MKSLLFLVLISICCAEPHLDHERIIHIQEDDGPRLSVVAEQSKVFSHRGGNVTLPCKFYRESISAGSGTHRIRVKWTKLTSDYLKEVDVFVAMGHHRKSYGNYQDRVFLKEGSSNDASLVITALTLEDYGKYKCEVIEGLEDDTAMVTLDLQGVVFPYFPWLGRYNLNFHEAQQACLDQDSVIASFDQLYEAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGKNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIQPTKLTYDEAVQACLKDGSQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRKRCSPNEAAVRFVGFPDKKHKLYGVYCFRSYN >XP_006270247.1 PREDICTED: hyaluronan and proteoglycan link protein 1 isoform X1 [Alligator mississippiensis] MKSLLFLVLISICCAEPHLDHERIIHIQEDDGPRLSVVAEQSKVFSHRGGNITLPCKFYRESISAGSGTHRIRVKWTKLTSDYLKEVDVFVAMGHHRKSYGNYQDRVFLKEGSSNDASLVITAVTLEDYGKYKCEVIEGLEDDTAMVTLDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDSVIASFDQLYEAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGKNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLKDGSQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRKRCSPNEAAVRFVGFPDKKHKLYGVYCFRAYN >XP_020749849.1 hyaluronan and proteoglycan link protein 1 [Odocoileus virginianus texanus] MKSLLLLVLISICWADHHVDHDRVIHIQAENGPRLLVEAEQAKVFSHRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCFRAYN >XP_040197640.1 hyaluronan and proteoglycan link protein 1 [Rana temporaria] MKRVLFLVLISFCWADHHVYNDRIIHV-HENGPRLVVEVDQTKVISHRGGNATLPCKFHHESVSAGSLSHKIRIKWTKLTSDYLKEVDVFVSMGHHKKSYGSYQGRVYLQGSSANDASLVITDITLEDYGRYKCEVIEGLEDDTAVVSLDLQGIVFPFFPRLGRYNLNFNEAQQACQDQDSIIASFDQLYDGWRSGLDWCNAGWLSDGSVQYPITNPREQCGGKNIVPGVRNYGYRDKDKGRYDVFCFTSNFKGRFYYLIHPVKLTYDEAIQACINDGAQIAKVGQMYAAWKLLGYDRCDGGWLADGSVRYPISKPRRRCSPNEAAVRFVGYPDKKHKLYGVYCYKA-- >XP_031573871.1 stabilin-1-like [Actinia tenebrosa] -------------------------------------------------------------------------------------------------MNEGTYHCNCSIQ-------------IPXLPYLDQHCAVDHSLMKKSGTF-----RNVFNLTIKLLRYALNYYEAERACAIFGAQXSSLTQLDDAWKAGFDSCRYGWLVDGTVRFPIIYPRQGC--SSSPPSIRGSTTQDKWNSRHDVYCYTDNCNDACYKFFLDTKARQTPAAQTCALEGGILGKAKLIFADQQILVGLSQDAGWTNGEAVRSSLWNXTQPTGPNXAXKALDNVPDSDEWKLPFVCQKPVP
PhyML tree of selected proteins (XP_010723327_1_hyaluronan_and_proteoglycan_link_protein_4__Meleagris_gallopavo_:0.95435073,((tr_Q1LXE1_Q1LXE1_DANRE_Hyaluronan_and_proteoglycan_link_protein_1a_OS_Danio_rerio_OX_7955_GN_hapln1a_PE_1_SV_1:0.63010013,(tr_E7FBW8_E7FBW8_DANRE_Hyaluronan_and_proteoglycan_link_protein_1b_OS_Danio_rerio_OX_7955_GN_hapln1b_PE_4_SV_1:0.14555175,(XP_031573871_1_stabilin_1_like__Actinia_tenebrosa_:5.12805464,(XP_015829432_1_PREDICTED__hyaluronan_and_proteoglycan_link_protein_1__Nothobranchius_furzeri_:0.13960951,(XP_030290935_1_hyaluronan_and_proteoglycan_link_protein_1_like__Sparus_aurata_:0.04058062,XP_023816569_1_hyaluronan_and_proteoglycan_link_protein_1_isoform_X1__Oryzias_latipes_:0.0943616):0.01783823):0.13130397):0.00000002):0.09793224):0.05564212,(XP_018099885_1_hyaluronan_and_proteoglycan_link_protein_1__Xenopus_laevis_:0.05204221,XP_040197640_1_hyaluronan_and_proteoglycan_link_protein_1__Rana_temporaria_:0.06307263):0.05208124):0.01942861,(((NP_001004028_1_hyaluronan_and_proteoglycan_link_protein_1_precursor__Sus_scrofa_:0.0172727,((XP_020749849_1_hyaluronan_and_proteoglycan_link_protein_1__Odocoileus_virginianus_texanus_:0.00000001,(XP_043320652_1_hyaluronan_and_proteoglycan_link_protein_1_isoform_X1__Cervus_canadensis_:0.00000001,(NP_776713_1_hyaluronan_and_proteoglycan_link_protein_1_precursor__Bos_taurus_:0.00314618,(XP_004009120_1_hyaluronan_and_proteoglycan_link_protein_1__Ovis_aries_:0.00000001,XP_005683456_1_PREDICTED__hyaluronan_and_proteoglycan_link_protein_1__Capra_hircus_:0.00000001):0.00000001):0.00312154):0.00000001):0.0031468,((KAB0363570_1_hypothetical_protein_FD754_007726__Muntiacus_muntjak_:0.00000001,KAB0387446_1_hypothetical_protein_FD755_002402__Muntiacus_reevesi_:0.00000001):0.00000001,OWK12308_1_HAPLN1__Cervus_elaphus_hippelaphus_:0.00573454):0.05265935):0.00527842):0.00344277,(((XP_002815765_2_hyaluronan_and_proteoglycan_link_protein_1__Pongo_abelii_:0.00314952,(XP_018884172_1_hyaluronan_and_proteoglycan_link_protein_1__Gorilla_gorilla_gorilla_:0.00000001,(sp_P10915_HPLN1_HUMAN_Hyaluronan_and_proteoglycan_link_protein_1_OS_Homo_sapiens_OX_9606_GN_HAPLN1_PE_2_SV_2:0.00315025,(XP_001147083_1_hyaluronan_and_proteoglycan_link_protein_1__Pan_troglodytes_:0.00000001,XP_003822290_1_hyaluronan_and_proteoglycan_link_protein_1__Pan_paniscus_:0.00000001):0.00315328):0.00314901):0.00632758):0.00637358,(XP_002713942_1_PREDICTED__hyaluronan_and_proteoglycan_link_protein_1_isoform_X1__Oryctolagus_cuniculus_:0.02274385,(NP_062062_2_hyaluronan_and_proteoglycan_link_protein_1_precursor__Rattus_norvegicus_:0.01606094,NP_038528_3_hyaluronan_and_proteoglycan_link_protein_1_precursor__Mus_musculus_:0.00000001):0.01943027):0.00295918):0.00319349,(XP_849484_1_hyaluronan_and_proteoglycan_link_protein_1__Canis_lupus_familiaris_:0.02235102,XP_006927896_1_hyaluronan_and_proteoglycan_link_protein_1_isoform_X1__Felis_catus_:0.00636576):0.00638133):0.00327944):0.04200262,((XP_005515977_1_hyaluronan_and_proteoglycan_link_protein_1_isoform_X1__Columba_livia_:0.01129103,NP_990813_1_hyaluronan_and_proteoglycan_link_protein_1_precursor__Gallus_gallus_:0.02597953):0.035649,(XP_006270247_1_PREDICTED__hyaluronan_and_proteoglycan_link_protein_1_isoform_X1__Alligator_mississippiensis_:0.00299888,XP_006021303_1_hyaluronan_and_proteoglycan_link_protein_1__Alligator_sinensis_:0.01250733):0.05736533):0.04520399):0.05140041);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)