PB0075

DATABASE

Click here to access PB0075 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0075	P14543	Nidogen-1	NID1	NID	Homo_sapiens	Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions.

Domains

Gene Ontology

PF00058 (3_Ldl_recept_b) PF00086 (Thyroglobulin_1) PF06119 (NIDO) PF07474 (G2F) PF07645 (EGF_CA) PF12662 (cEGF) PF12947 (2_EGF_3)

GO:0005201 (enables) extracellular matrix structural constituent GO:0005509 (enables) calcium ion binding GO:0005518 (enables) collagen binding GO:0043236 (enables) laminin binding GO:0043237 (enables) laminin-1 binding GO:0043394 (enables) proteoglycan binding GO:0050840 (enables) extracellular matrix binding GO:0007155 (involved in) cell adhesion GO:0007160 (involved in) cell-matrix adhesion GO:0010811 (involved in) positive regulation of cell-substrate adhesion GO:0030198 (involved in) extracellular matrix organization GO:0032836 (involved in) glomerular basement membrane development GO:0071711 (involved in) basement membrane organization GO:0005886 (is active in) plasma membrane GO:0005576 (located in) extracellular region GO:0005604 (located in) basement membrane GO:0031012 (located in) extracellular matrix GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome GO:0071944 (located in) cell periphery

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P14543|NID1_HUMAN Nidogen-1 OS=Homo sapiens OX=9606 GN=NID1 PE=1 SV=3 MLASSSRIRAAWTRALLLPLLLAGPVGCLSRQELFPFGPGQGDLELEDGDDFVSPALELS GALRFYDRSDIDAVYVTTNGIIATSEPPAKESHPGLFPPTFGAVAPFLADLDTTDGLGKV YYREDLSPSITQRAAECVHRGFPEISFQPSSAVVVTWESVAPYQGPSRDPDQKGKRNTFQ AVLASSDSSSYAIFLYPEDGLQFHTTFSKKENNQVPAVVAFSQGSVGFLWKSNGAYNIFA NDRESVENLAKSSNSGQQGVWVFEIGSPATTNGVVPADVILGTEDGAEYDDEDEDYDLAT TRLGLEDVGTTPFSYKALRRGGADTYSVPSVLSPRRAATERPLGPPTERTRSFQLAVETF HQQHPQVIDVDEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTG NGRQCVAEGSPQRVNGKVKGRIFVGSSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETV GYSLLPLAPVGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGI DEHGHLTIDTELEGRVPQIPFGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGAS PSRIYTYQWRQTITFQECVHDDSRPALPSTQQLSVDSVFVLYNQEEKILRYALSNSIGPV REGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSV CGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYT GGSSYTCSCLPGFSGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV PGEVEKTRCQHEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVD RDGREVEGTRTRPGMTPPCLSTVAPPIHQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLE GNTMRKTEAKAFLHVPAKVIIGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDL GSPEGIAVDHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYW TDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAFSSQLCWVDAGTNRAECLNPSQ PSRRKALEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAFQPHKQTRLYGITT ALSQCPQGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIEQK >tr|F1RAG3|F1RAG3_DANRE Nidogen 1a OS=Danio rerio OX=7955 GN=nid1a PE=1 SV=2 MGRHGHRHPFWVILFGLTLSVSGITRHELFPFGRNAGDQSLREGNDETQEVNLDKPITFH DEQFSKIYINTNGFVALEKPTGESEYLENMPASFKMIAALQGDLDTSDGVGKVFFRQDFS TALLQQAADHINRAFPEDDLVNPIHALVVTWLDVASHKAESRGDGLEHSIRRNTFQLVIA SVETSSYAILLYPRDSIQFQSTGSGYTVHAGFSKTQELYYRNTEDTEASVKDLPEQTNSG KRGVWVYEIGTFPHFTNIAPGEVPDLPLDSLRRSETQNQQQQVYPDVQQENLDGVYHHPE HPPPIQVHTVQFTPQDPQVVEIENDDNIQVDVFTYNSGQCGGQKCSKFAECSGRCCVCKP GYYGSGVHCVPEGVPQRMNGKVSGRVFVGNSPVPVDFASNDLHSYVVANDGRAYVAISAI PPVIGFSLQPLSSVGGVIGWAFALQQPGFKNGFSIIGGEFKRQADVSFQPGGEKLTISQE FRGIDEHDHLMVDTRLEGKIPEVPQGATVQIDSYSEIYQYSINLITSSSTREYVISLPDG STQSRSYNFRETITFQGCQFDEVPSTQMLSVEQVFVMYDMGAQLLRYAMSNKIGDVNGGQ SEENACFTGRHGCDTNAVCKPGQGNQFTCECAAGFTGDGRACYDIDECRETPQICGQNSI CNNQPGTFRCECLDGFQFASDGQTCVEVHRPVDPCRSGTHDCDVPERARCSYTGGSSYIC TCAPGFMGDGRRCQDIDECQVNQCHENAVCFNTPGSFSCQCNPGFHGDGFYCSTEREKTR CELHKESVVGFGPHSARPQPGRFVPTCDAQGRYEPMQCHASIGQCWCVDRDGEEISGTRT GPGRFPVCRGHDESGPIRPTPNPNISPLPPGSHILFTQSGKIEYIPLDGHNLKKNEAKTA LHLPEKVVIGIAYDCVEKMIYWTDISTPAISRANLQGGEPVQLIKSDIGSPEGIAIDHLG RNMFWTDSMKDRIEVSSLDGTQRRVLVNTDLVNPRAILTDSTNGYIYWADWNRESPKIEM AYMDGTNRRVLAKDDLSLPNGLTYDPQTSLLCWADAGTHKVECMNPQQGRRTQLMEEIQY PFGLTTDGKNFYYTDWTRVSVVVVDRHLRREVDEFQPQKRTRLYGITTAHARCPAGQNYC SSNNGGCTHLCLATPAGRSCRCPDNAAELGCVERE
Selected proteins from model organisms >sp|P14543|NID1_HUMAN Nidogen-1 OS=Homo sapiens OX=9606 GN=NID1 PE=1 SV=3 MLASSSRIRAAWTRALLLPLLLAGPVGCLSRQELFPFGPGQGDLELEDGDDFVSPALELS GALRFYDRSDIDAVYVTTNGIIATSEPPAKESHPGLFPPTFGAVAPFLADLDTTDGLGKV YYREDLSPSITQRAAECVHRGFPEISFQPSSAVVVTWESVAPYQGPSRDPDQKGKRNTFQ AVLASSDSSSYAIFLYPEDGLQFHTTFSKKENNQVPAVVAFSQGSVGFLWKSNGAYNIFA NDRESVENLAKSSNSGQQGVWVFEIGSPATTNGVVPADVILGTEDGAEYDDEDEDYDLAT TRLGLEDVGTTPFSYKALRRGGADTYSVPSVLSPRRAATERPLGPPTERTRSFQLAVETF HQQHPQVIDVDEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTG NGRQCVAEGSPQRVNGKVKGRIFVGSSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETV GYSLLPLAPVGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGI DEHGHLTIDTELEGRVPQIPFGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGAS PSRIYTYQWRQTITFQECVHDDSRPALPSTQQLSVDSVFVLYNQEEKILRYALSNSIGPV REGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSV CGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYT GGSSYTCSCLPGFSGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV PGEVEKTRCQHEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVD RDGREVEGTRTRPGMTPPCLSTVAPPIHQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLE GNTMRKTEAKAFLHVPAKVIIGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDL GSPEGIAVDHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYW TDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAFSSQLCWVDAGTNRAECLNPSQ PSRRKALEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAFQPHKQTRLYGITT ALSQCPQGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIEQK >tr|F1RAG3|F1RAG3_DANRE Nidogen 1a OS=Danio rerio OX=7955 GN=nid1a PE=1 SV=2 MGRHGHRHPFWVILFGLTLSVSGITRHELFPFGRNAGDQSLREGNDETQEVNLDKPITFH DEQFSKIYINTNGFVALEKPTGESEYLENMPASFKMIAALQGDLDTSDGVGKVFFRQDFS TALLQQAADHINRAFPEDDLVNPIHALVVTWLDVASHKAESRGDGLEHSIRRNTFQLVIA SVETSSYAILLYPRDSIQFQSTGSGYTVHAGFSKTQELYYRNTEDTEASVKDLPEQTNSG KRGVWVYEIGTFPHFTNIAPGEVPDLPLDSLRRSETQNQQQQVYPDVQQENLDGVYHHPE HPPPIQVHTVQFTPQDPQVVEIENDDNIQVDVFTYNSGQCGGQKCSKFAECSGRCCVCKP GYYGSGVHCVPEGVPQRMNGKVSGRVFVGNSPVPVDFASNDLHSYVVANDGRAYVAISAI PPVIGFSLQPLSSVGGVIGWAFALQQPGFKNGFSIIGGEFKRQADVSFQPGGEKLTISQE FRGIDEHDHLMVDTRLEGKIPEVPQGATVQIDSYSEIYQYSINLITSSSTREYVISLPDG STQSRSYNFRETITFQGCQFDEVPSTQMLSVEQVFVMYDMGAQLLRYAMSNKIGDVNGGQ SEENACFTGRHGCDTNAVCKPGQGNQFTCECAAGFTGDGRACYDIDECRETPQICGQNSI CNNQPGTFRCECLDGFQFASDGQTCVEVHRPVDPCRSGTHDCDVPERARCSYTGGSSYIC TCAPGFMGDGRRCQDIDECQVNQCHENAVCFNTPGSFSCQCNPGFHGDGFYCSTEREKTR CELHKESVVGFGPHSARPQPGRFVPTCDAQGRYEPMQCHASIGQCWCVDRDGEEISGTRT GPGRFPVCRGHDESGPIRPTPNPNISPLPPGSHILFTQSGKIEYIPLDGHNLKKNEAKTA LHLPEKVVIGIAYDCVEKMIYWTDISTPAISRANLQGGEPVQLIKSDIGSPEGIAIDHLG RNMFWTDSMKDRIEVSSLDGTQRRVLVNTDLVNPRAILTDSTNGYIYWADWNRESPKIEM AYMDGTNRRVLAKDDLSLPNGLTYDPQTSLLCWADAGTHKVECMNPQQGRRTQLMEEIQY PFGLTTDGKNFYYTDWTRVSVVVVDRHLRREVDEFQPQKRTRLYGITTAHARCPAGQNYC SSNNGGCTHLCLATPAGRSCRCPDNAAELGCVERE >NP_035047.2 nidogen-1 precursor [Mus musculus] MLDASGCSWAMWTWALLQLLLLVGPGGCLNRQELFPFGPGQGDLELEAGDDVVSPSLELIGELSFYDRTD ITSVYVTTNGIIAMSEPPATEYHPGTFPPSFGSVAPFLADLDTTDGLGNVYYREDLSPFIIQMAAEYVQR GFPEVSFQPTSVVVVTWESVAPYGGPSSSPAEEGKRNTFQAVLASSNSSSYAIFLYPEDGLQFFTTFSKK DESQVPAVVGFSKGLVGFLWKSNGAYNIFANDRESIENLAKSSNAGHQGVWVFEIGSPATAKGVVSADVN LDLDDDGADYEDEDYDLVTSHLGLEDVATPSPSHSPRRGYPDPHNVPRILSPGYEATERPRGVPTERTRS FQLPAERFPQHHPQVIDVDEVEETGVVFSYNTGSQQTCANNRHQCSVHAECRDYATGFCCRCVANYTGNG RQCVAEGSPQRVNGKVKGRIFVGSSQVPVVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGG IIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFLGHPGKLVLKQQFSGIDEHGHLTISTELEGRVPQIPYG ASVHIEPYTELYHYSSSVITSSSTREYTVMEPDQDGAAPSHTHIYQWRQTITFQECAHDDARPALPSTQQ LSVDSVFVLYNKEERILRYALSNSIGPVRDGSPDALQNPCYIGTHGCDSNAACRPGPGTQFTCECSIGFR GDGQTCYDIDECSEQPSRCGNHAVCNNLPGTFRCECVEGYHFSDRGTCVAAEDQRPINYCETGLHNCDIP QRAQCIYMGGSSYTCSCLPGFSGDGRACRDVDECQHSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCMPG EVSKTRCQLEREHILGAAGGADAQRPTLQGMFVPQCDEYGHYVPTQCHHSTGYCWCVDRDGRELEGSRTP PGMRPPCLSTVAPPIHQGPVVPTAVIPLPPGTHLLFAQTGKIERLPLERNTMKKTEAKAFLHIPAKVIIG LAFDCVDKVVYWTDISEPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRTIFWTDSQLDRIEVAKMDG TQRRVLFDTGLVNPRGIVTDPVRGNLYWTDWNRDNPKIETSHMDGTNRRILAQDNLGLPNGLTFDAFSSQ LCWVDAGTHRAECLNPAQPGRRKVLEGLQYPFAVTSYGKNLYYTDWKTNSVIAMDLAISKEMDTFHPHKQ TRLYGITIALSQCPQGHNYCSVNNGGCTHLCLPTPGSRTCRCPDNTLGVDCIERK >XP_043332969.1 nidogen-1 isoform X1 [Cervus canadensis] MLATVRRSGAAWTRALLLQLLLAGPGGCLSRQELFPFGPEHGDLELEAGDDLVSPALELSTALHFFDRSDIDSVYVTTNG IIAMSEPPAKETHPGPFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSVTQLAAECVQRGFPEVSFKPSSAVVVTWESV APYQGPSKDPALEGKRNTFQSILASSDSSTYAIFLYPEDGLQFYTTFSKKEENQVPAVVAFSQGLVGLIWKSDGAYNIFA NDRESIGNLAKSSNSGQQGIWVFEIGSPATASGVVPADVNLGLDDGAEYDDEDYDSVTRLGLEDVVTTSFPYEAPRRGDS GTYNTPSDLSPRRMATERPLTPPTERTRSFQLPGERFPQQQPQVIDVDEVEETGIVFSYNTDSRQTCATNRHQCSVHAQC RDFATGFCCRCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGASQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYS LLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPDKLIVKQQFSGIDEHGHLTIDTELEGRVPQIAFGS TVHIEPYMELYHYSRRVITSSSTREYTVTEPERDGTSPSHVHTYQWRQTITFQECVHDDSGPVLPSTQQLSVDSVFVLYN QEERILRYALSNSIGPVRDGSPDALQNPCYIGSHGCDANAACRPGPGTRFSCECSVGFRGDGRACYDIDECSEQPSVCGN HAICNNHPGTFRCECVEGYRFSEAGTCVAVMDQRPVNYCETGLHDCDIPQRAQCIYTGGSSYTCSCLPGFSGDGRACKDV DECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFHCVPGEVEKTRCQLEREHILGAVDSQRPRPPGLFVPECDEHGHYAP VQCHGSTGYCWCVDRDGREVQGTRTRPGMRPPCLSTVAPPVHHGPPVPTAVIPVPPGTHLLFAQTGKIEHLPLEGSTMTK SEAKALLHAPDKVIIGLAFDCVDKMVYWTDISQPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSHLDRIE VAKLDGTQRRVLFETDLVNPRGIATDSVRGNLYWADWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCWV DAGTHRAECLKPGQPNRRTVLEGLQYPFGVTSFGKNLYYTDWKTNSVVAVDLAISKETDSFHPHKQTRLYGITSALSQCP EGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIEQK >KAF4018772.1 hypothetical protein G4228_010616 [Cervus hanglu yarkandensis] MLATVRRSGAAWTRALLLQLLLAGPGGCLSRQELFPFGPEHGDLELEAGDDLVSPALELSTALHFFDRSDIDSVYVTTNG IIAMSEPPAKETHPGPFPPTFGAVAPFLADLDTTDGLGKIYYREDLSPSVTQLAAECVQRGFPEVSFKPSSAVVVTWESV APYQGPSKDPALEGKRNTFQSILASSDSSTYAIFLYPEDGLQFYTTFSKKEENQVPAVVAFSQGLVGLIWKSDGAYNIFA NDRESIGNLAKSSNSGQQGIWVFEIGSPATASGVVPADVNLGLDDGAEYDDEDYDSVTRLGLEDVVTTSFPYEAPRRGDS GTYNTPSDLSPRRMATERPLTPPTERTRSFQLPGERFPQQQPQVIDVDEVEETGIAVFSYNTDSRQTCATNRHQCSVHAQ CRDFATGFCCRCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGASQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGY SLLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPDKLIVKQQFSGIDEHGHLTIDTELEGRVPQIAFG STVHIEPYTELYHYSRRVITSSSTREYTVTEPERDGTAPSHVHTYQWRQTITFQECVHDDSGPVLPSTQQLSVDSVFVLY NQEERILRYALSNSIGPVRDGSPDALQNPCYIGSHGCDANAACRPGPGTRFSCECSVGFRGDGRACYDIDECSEQPSVCG NHAICNNHPGTFRCECVEGYRFSEAGTCVAVMDQRPVNYCETGLHDCDIPQRAQCIYTGGSSYTCSCLPGFSGDGRACKD VDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFHCVPGEVEKTRCQLEREHILGAVDSQRPRPPGLFVPECDEHGHYA PVQCHGSTGYCWCVDRDGREVQGTRTRPGMRPPCLSTVAPPVHHGPPVPTAVIPVPPGTHLLFAQTGKIEHLPLEGSTMT KSEAKALLHAPDKVIIGLAFDCVDKMVYWTDISQPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSHLDRI EVAKLDGTQRRVLFETDLVNPRGIATDSVRGNLYWADWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCW VDAGTHRAECLKPGQPNRHTVLEGLQYPFGVTSFGKNLYYTDWKTNSVVAVDLAISKETDSFHPHKQTRLYGITSALSQC PEGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIEQK >XP_018118629.1 nidogen-1 isoform X1 [Xenopus laevis] MLYFKQKGLFFGGLLHVLFCLLPNPGSFIKVDTFFPYGRDVGDLLLTPGDDSDSEPLRPNQSLHFYDGTISTLFVTTNGM IATSKPPPEDDYLEQFPPDFGLIAPFLSDIDTSEGGNVFYREDTSQDVLHLASKHINRGFPGSTFIPKSALVFTWEDVLP YYSQRGDAIPHNKGNTFQAVLASDESKSYAIFLYPEDGLNFHGTQPKNNYNEENSARVGFSKGAEAFILWKTKGPHNEFA NDYYSLEMLRWKTNSGMQGVWIYEIGGPSTLKSVVAANVEHFATLDEKEENHSEETEDFNDHYVTEQDYENNPLKPNIPG LNLIPVDPYLDQEDVILGNVNFQVPSFPQNNPQIVIVDDELEDTGVVFQYNTGNQQTCANNRHQCSSQAFCKDYSTGFCC TCIPGYYGNGRQCVAEGSPQRVNGKVKGKIYVGSNPIPVVFEGIDLHSYVVVNDGRAYTAISTIADSLGYSLLPLASIGG VIGWMFSVQQPGYKNGFSITGGEFTRKTEVTFLHSNKKLVILQKFSGIDEHGHLTISTELDGSVPEIPYGSTVHIEPYTE LYQTSSSVITSSSNREYTVEFPQDGSETFTYQWKQTITFTECVHDTAAPTVPAIQQLSVDRVFVLYNREEKILRYASSNS IGPITDSPVDTNRNPCYIGAHNCDTNAVCRPAQGNQYICECTSGFRGDGRTCYEIDECQEQQDICGDNAICNNQPGTFRC ECNDGYQFLEDGRTCASVERTINHCLTGTHNCDIAERAHCIYTGGSSYICACLSGYSGDGRVCEDVDECETSQCHPDAVC YNIPGSFSCHCKPGYQGNGFQCFPGEPQKTPCQLHQDSILGSPSVRGARPVGQFLPQCDESGNYVPRQCHSGSGYCWCVD KDGNELPGTRTRPGLSPPCLDIVTHPPPTVGPVVRPDVAPLPPGTHLLFVQSGKIEHVPLEGNSMKKSDAKTLLHIPDKV IIGVSYDCVDKTVYWTDITGPSISRASINGGEPTAIIKTELGSPEGIAVDHLGRNIFWTDSVLNTIEVAKLDGSNRRILF DTDLENPRGIVADALKGNLYWTDWNRVAPKIETSYMDGTNRRILVKDDLGLPNGLTIDAYSSMLCWVDAGTKRMECMNPS QPARRKIVEGIQYPFGITSYGKNIFYTDWKRDSIVAIDRTISKENDNFQPPKRSRLYGITTAYSQCPQGQNYCAVNNGGC KHLCLATPGGRSCLCPENSTGVDCLDRN >XP_040188888.1 nidogen-2 [Rana temporaria] MVSRVLRILHWHCLLLGFSAAISRQELFPYGESRGDRLLPDGDDETSEVVTLTQPILFYEADFKELYVGTNGIISTQDFP RETQYVDDGFPTDFPVIAPFLSDIDTSNGKGKIYYRQDNSPDILSTVARQVDRGFPQAAFSPTNVFMVTWDNVGAYEEVT RHAEPSNKLNTFQAVLAYDDSDTYAIFLYPEHGLQFFGTRPKESYNVHLDLPARVGFSRGDSEMLKKEAPFYSVTSSEQS VKNLYQTSNVGVPGVWVFHIGSLSEIDNVIPAKVPHHHPQQRFVPLINSHNDFPEQQQQQQLENQFNGENNYEDNYEDED YPAGQTTEAPTTDSAVLNPDRTHDFIDAEDHATLYTPNNPLPPSQEEPSWTPYNPDEPLVEPEIQRSESRVLGNIPSYET QEEPSESVSEDFNNVTPNPVDPQRSDVYRSNRFYGNEEVGGLDTDVLTFNPVSRETCDRKPGYCSPYAFCTDYATGFCCH CQDSYYGNGVHCLPKGAPHRVNGKVSGNLLVGQRPVTFDGIDMHAYIVVNDGRAYTAISQVPEPASWSLTPLTAIGGLFG WLFALEKPGHQNGFSITGAKFVHNLEAVFSPGEEVIHVTQTADGFDSDNYIHVRTTIKGKIPYIPETSTVQIAPYYEIYQ HSGSVVTSTAYREYTVTSQSGDVQKFSYRLKQNITYQECGHAQKYPPTAQKLSVDRVFAMHNKDEKVLRFAITSHIGSLH DSSQEPTQGNPCFDGTHQCDTRAQCQPATGLNYSCVCASGYRGDGRDCTDYDECEDQLDNCGQNTRCVNLPGSFRCECVP GYVFSADGQNCILGSSFGNPCEDGTHSCDLTTSQCVPRGDGVFTCECFPGYTRSGQSCIDVDECAERRCHPDATCANVPG SFSCRCNPGFTGDGFQCTQAPEEPRPSTPCLEKRHAAQPRGPRPPLIGAFLPECDEEGNYVPLQCHGSTGHCWCVDRNGN EIEGTRRPAGSGRPQCGIPEPTQRPQTMCERWKQSLVDHYGGSPSAEHYIPQCDAYGEFSPLQCHGNSGYCWCVDKDGRE IEGSRTQPGMTPACLPSVAPPTVRPTPRPDVTPPTSGTYLLYAQGQQIGYLPLDGVKFRKDKARTLLALHGSIVVGIDYD CQEKKVYWTDVSGRTISRAGLEPGAEPEVLISTDLMSPEGLAIDYLRKTMFWTDSGTDKIESARLDGTFRKTLFDTNLVN PRAITVDAVRGNLYWTDWNREAPKIETSYVDGSNRRILVNDNIGLPNGLTFDPFSKQICWADAGTKKLECILSDGSGRRV IQSNLNYPFSVVGFANHFYHTDWRRDGVISINKENGQITEEYLPEQRSHLYGITAIYPYCPSGKK >OWK09497.1 NID2 [Cervus elaphus hippelaphus] MGATRVPPQLVAIRRQVWPTPASVHLDVDECATGFHRCGPNSVCVNLLGSYRCECRSGYEFADDRHTCILITPPPDPCED GRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTDVDECSENRCHPSATCSNTPGSFSCRCQPGYYGDGFQCTPEPT QRPRTVCERWRESLLEHYGGTPRDDQYVPQCEGLGHFTPLQCHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPT IRPTPRPDVTPPPVGTFLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLE PGAEPETVINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREA PKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQNNLNYPFNIVSYADHFYHTD WRRDGVIAVNRDTSQFTDEYLPEQRSHLYGITAVYPYCPGKQLLRQRLGISRVEEHRSSS >XP_213954.4 nidogen-1 [Rattus norvegicus] MLDASGWSWEMWTWALLQLLLLAGPAGCLSRQELFPFGPGQGDLELEAGDDVVSPSLELIGELSFYDRSD ITSVYVTTNGIIAMSEPPATEFHPGTFPPSFGSVAPFLADLDTTDGLGNVYYREDLSPFIIQMAAEYVQR GFPEVSFQPTSVVVVTWESMAPYGGPSGSLVEEGKRNTFQAVLASSNSSSYAIFLYPDDGLQFFTTFSKK DENQVPAVVGFSKGLEGFLWKSNGAYNIFANDRESIENLAKSSNAGHQGVWVFEIGSPATAKGVVPADVN LDVDDDGADYEDEDYDLQTSHLGLEDVATQPFPSHSPRRGYPDPHNVPRTLAPSYEATERPHGIPTERTK SFQLPVERFPQKHPQVIDVDEVEETGVVFSYNTGSQQTCANNRHQCSVHAECRDYATGFCCRCVANYTGN GRQCVAEGSPQRVNGKVKGRIFVGNSQVPVVFENTDLHSYVVMNHGRSYTAISTIPESVGYSLLPLAPIG GIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFLGHPGKLILKQQFSGIDEHGHLTINTELEGRVPQIPY GASVHIEPYTELYHYSSSVITSSSTREYTVTEPDQDSAVPSHTHVYQWRQTITFQECAHDDSRPALPSTQ QLSVDSVFVLYNKEERILRYALSNSIGPVRDGSPDALQNPCYIGTHGCDSNAACRPGPGTQFTCECSVGF RGDGKACYDIDECSEQPSRCGNHAICNNHPGTFRCECMEGYHFSDRGICVAAVDQRPINYCETGLHNCDI PQRAQCIYMGGSSYTCSCLPGFSGDGRACQDVDECQHSRCHPDAFCYNTPGSFRCQCKPGYQGDGFRCVP GEVGKTRCQLEREHILGAAGATDAQRPTLQGMFVPQCDEYGHYTPTQCHHSTGYCWCVDRDGQELEDTRT PPGMRPPCLSTVAPPIHQGPVVPTAVIPLPPGTHLLFAQTGKIERLPLERNTMKKTEAKAFLHIPAKVII GLAFDCVDKVVYWTDISEPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRTIFWTDSHLDRIEVAKMD GTQRRVLFDTGLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSHMDGTNRRILAQDNLGLPNGLTFDAFSS QLCWVDAGTHRAECLNPAQPSRRKVLEGLQYPFAVTSYGKNLYYTDWKTNSVIAMDLAVSKEMDAFHPHK HTRLYGITIALSQCPQGHNYCSVNNGGCTHLCLPTPGSRTCRCPDNTLGVDCIERK >XP_040524442.1 nidogen-1 isoform X1 [Gallus gallus] MGVGTRCAPCALLALALPLALPAELLLPHGAERGDAALEPGDDARSAALELGTALHFYGAAVRSLYVATN GIIAVNEPKNEEKYLGQFPVSFGAIAPFMADLDTTDGRGNVYYREDSSSDVLQLASDYIKGGFPEAAFDP SSAVIVTWKLVAPYQGPGEDLTLEEKRNTFQAVLASSDSSSYAIFLYPEDGLQFYSAYSKNDDGKIPAMV GFSQASTNYYFWENPGSYNVIANDEDSIRNLHKSSNAGRQGVWVFEIGSSSDTIVPAKVSSVLASLEPSE EDQELTSKPFMSDYGSTEIRPQYVTSSTDSIEEDQHVTYSVPQLAVEDFITSYQDVTGTPSTESFYRHRE FPTAKAPPRQFPAQQFPPQGPQVIDVEEFDETGIVFRYHTDVQQTCANNRHQCSVHAICKDYPNGFCCSC IAGYKGNGRQCVAEGSPQRVNGKVKGRVFVGNNPVPVTFENTDLHSYVVMNHGRAYTAISTIPEALGYSL LPLASIGGVIGWMFAVEQQGYKNGFSITGGEFTRQTEVTFLGNNEKLVIKQKFSGIDEHGHLTISTEMEG RVPEVPSGASVHIEPYTELYHASSSVITSSSTREYTVTEPERDGVASTYTGAYQWRQTISFDECIHDDSL HAASATQQLSVDSIFVLYNRDEQILRYAMSNSIGPISDGSADISRNPCYTGTHNCDTNAVCRAGTGNRFS CECSIGFRGDGNVCYDIDECSEQPGLCGSNAVCNNQPGTYRCECVDGYQFAADGRTCVAVEYAINHCQTG THGCDIPQRAQCVYTGGSAYICTCLPGFSGDGRACEDIDECQQGHCHPDAFCYNTPGSFSCQCKAGYRGD GFQCVLGGVVKTKCQHEKEVALGSGGTFFQREIRVGQFIPQCDEHGNYVPTQCHGSTGYCWCVDRDGNEI DGTRSGPGVRPPCLSTAAPPVGIGPSVRPDTIPLPPGTHLLFAQSGKIEHVPLEGNNMKKNGAKALLHIP DKVIIGVAYDCMDKMVYWTDISGPSISRASLHGGEPTTIIRTDLGSPEGIALDHLGRNIFWTDSQLDRIE VARLDGRQRRILFDTGLVNPRAIVVDPVRGNLYWTDWNREAPKIETSYMDGTNRRILVKDDLGLPNGLTF DPYSSMLCWVDAGTKRLECMNPNQLGRRKIVEGIQYPFGVTSYGKNLYYTDWRRDAVVAVDRMISVENDN FQPHKRSRLYGITTAFAQCPGGHNYCTVNNGGCTHLCLATPEGRSCRCPDNTVGVDCIERN >XP_001156001.1 nidogen-1 [Pan troglodytes] MLASSSRIRAAWTRALLLPLLLAGPVGCLSRQELFPFGPGQGDLELEDGDDLVSPALELSGALRFYDRSD IDSVYVTTNGIIATSEPPAKESHPGLFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSITQRAAECVHR GFPEISFQPSSAVVVTWESVAPYQGPSRDPDQKGKRNTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKK ENNQVPAVVAFSQGSVGFLWKSNGAYNIFANDRESIENLAKSSNSGQQGVWVFEIGSPVTTNGVVPADVI LGTEDGAEYDDEDEDYDLATTRLGLEDVGTTPFSYKALRRGGADTYSVPSVLSPRRAATERPLGPPTERT RSFQLAVETFHQQQPQVIDVDEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTG NGRQCVAEGSPQRVNGKVKGRIFVGSSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPV GGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGIDEHGHLTIDTELEGRVPQIP FGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPSRIYTYQWRQTITFQECVHDDSRPALPST QQLSVDSVFVLYNQEEKILRYALSNSIGPVREGSPDALQNPCYLGTHGCDTNAACRPGPRTQFTCECSIG FRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCD IPQRARCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV PGEVEKTRCQHEREHILGAAGAADPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTR TRPGMTPPCLSTVAPPIHQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLEGNTMRKTEAKAFLHVPAKVI IGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAKL DGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDVFS SQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAFQPH KQTRLYGITTALSQCPRGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIERK >XP_791550.3 nidogen-1 [Strongylocentrotus purpuratus] MKLLLGIFAVLIAVVNCLPRDQFFPFGEGTTDKKLNRRSKKPLTLSFREPFTFLGEEQSLLYIVRDGYVSFSSGARGSKI APFHTKLKLIRGQSSVWYRTTVSSNEEDEIINLIQRNFRSRGSTDFTTFSPSSFVIVTWENMAVRNSDHEVIGTVTFQLI LVADAMHSFAFFLYDENNDYPRPDRIGSNIDAGFTSGKAHNQWEFEMVYTTEDNKAATLFEAMRDSNVGMNGMWAYKIDG RMDGNIIPAVAYVPVESLPQNDEPPQDAVNIQLDNTFDVVLDFENQCTRETCSVDGRCVPYPTGHCCACNEGFMGNGIHC LSINDNGRMNGRVNGTINGVTIPDEVYLHTFIMGGGGRTFTAISPVPSSIAYSMQILLPIGELMGWMFAEPAAKGINGFM QTGGDLLYSANIRFENGDEVSIIQRYTGVDESEEGGGVIGGYVTIDGNVPNLSPGTSVSVDRHSEVYTKYRPGYVYSSEQ RSLDADGQTIRFSIEQTITYQECEADDINTDASLTAMRMNTTYAYSIFEPQGDILRYAMITNVGPDIGVPTDACQDNNCG TNAECFPQANTFTCRCRAGYTGNGYTCTESPSDPCDNNDCDRNANCYPAGNSYTCQCNTGFNGDGRVCVADQASDPCDTN DCSLYAYCYPTNDGQSFYCQCATGFTGDGRNCEREQRGNACDNNNCSPYAYCRPRGDTDFTCECAPGYVGDGYNCEEESQ DPCLNNRCHPYADCSPVPGGYTCSCRSGYQGDGYLCEEADQLVNLCSDCGRDADCLPEGRGYRCICRAGFNGDGLTCEDV DECLEGADIACDANARCQNNRGSYTCRCNAGYRGDGFTCEALPEADGSLVFGQGMSVMNLPRDGSAGNKVYMKSRQTVVG LGYDCRHEYVYWTDISGRAIMKASLDGRDVSVVVNTSLSSPEGVAVDHLSRNLYWTDSGFDRIEVANLDGTNRHVLFDTD LVNPRAIVIDPVGGYLYWVDWDRSYPRIEVSGMDGSGRAVFLDEDLIMPNGLTIDLVSQLLCWADAGTQKVECMNLDGDP LSRYPVYRPAQYPFGLASLGNNLYWTDWQTSNIQFINKNGGEVQSLALPRGGNGRTYGIAAVTQCTDGNNRCAYENGGCR NLCLPAPGVRATCVCPNALAPNDIPCN >NP_001256467.1 NIDogen (basement membrane protein) [Caenorhabditis elegans] MKHKKMLILLFLYLLIETTTANPAFYPYGQPAGDNRLDYSMEQSAIALKIPLTYMEQSVDELFLSHNGIVGLGKPTPEKI GGLMTISTPAIAVFYVPVTSGVIDYRVSSDDQGLLTKLTQDVKQVFADAVEFHGLQAVIITWTQIENAEKDGPASFQLAI VSDGISTYAIFRYESLPWSSSMGYYAQAGFVRSIGKIQTNVNSGGPDVKELVNLSNNQFGNFFIFRVSGSAIEDPKDEGA DDYDYNNYDQEYEGEHPADCPKDKFVDNCPAECRTVRDERGCERCICAERPHAPRAPQEPRPELENTVEDDEDDEQVDGT RYEEPARQAQEQHHQQHHQPDQPQQQPQRSQEGSLPKMSCSQRDDKSCHANSVCQDFEGGFCCNCDTGFYGNGKECLPKG EPQRISGSFEGVINRIPIDKTELHTFATSTDGNVHTAVSKIPSDLGHPLRFLYSIGGVMGWLFADVQSPNVYNGFQLTGG LFNRTVALHIEQNYYVTIKQEFSGRNIHDYFKSHLFVSGTLPDIAPGSEVIFPDYEEEYVRERRGYLTSKAAFDVIVRDG GNVQTYRMSVDQQITFEECPNKEFDRDHSMKLHVKRINVVYNDDEGVVRYGAKNFATRSVGPAVSAPSGGHFDRRQHGQS NMASERPIEIPSQSESISTDSVCAPGRHQCTLPNMKCRVVDPSYRCECEPGYQAAHDASSHIGWICQDLDECQRGDHNCD QHAKCTNRPGSFSCQCLQGYQGDGRSCIREHQASHHEHNQQTPQEMAGVGATTEGFCTAHNQCHQWGECVFTSEHPTGRC KCRGWYVGDGVNHCGPPEENMPKHNANIPQRGGQACGSYVCDVNAECMPEPSGGSECVCKAGFSGNGVTCESLLDDRHAH SSHNRHEQQQQTGSLGKVCRSHDECSEHGSCAYHHSLGYYQCACTEPYVGNGVECTLPGSSASAESSTRSDKLLVARGMA IFERSTNPDEYGKQLIVIPHHIPVGIDFDCKEEKIVWSDMSGHSIRTSSLNGTEHKSYFNKELSSPEGIAVDWSSRNVYY ADSMNDEIGVASLNGKFKKSLVTEGLVNPRSVVLDLYGRHLYYSDWHRENPYIGRVDMDGKNNRVFLNEDVHLPNGLTIL PNRRELCWVDAGNHRLSCIQYNGAGRRTVFSSLQYPFGLTHDEEQKFYWTDWKDNRIHSVGVYGEGYRSFQISLGGSGKV FGILAVPKSCVGPSTPCSEDNGGCQHLCLPGQNGAVCECPDNVKVKGC >XP_038046995.1 fibropellin-1-like isoform X27 [Patiria miniata] MAWLFALPSGKGYNGFMLTGGKFRQTLNITFSTGEQMLITQDFQGVDENGYIRVIADWNGNIPEITPSDYVFVDDHKEEY VRHRLGVIHTFAKRSLQVNDDTISYTMDQTIEYDECSADEADTEYILNFMRVSMTETYLIYEASEEILRFSMIGKVTPAS EQIDDPCVSNNCDRNAQCLPAGDSGFRCKCNEGYEGNGQTCTGSNPCAQNSCDVNGYCIPQADRYTCACNAGYQGDGYTC SVDRCASSRCDPNARCVETTQGYECYCNAGFTGDGFRCQEEESDHCANNNCDPNARCVSAVFGYQCFCDPGYRGDGYTCQ ANNATDPCANHTCDTNARCVASAQDTYECYCFEGYTGDGFTCEVDPANPCASNTCDANARCVASAQDAYECSCLEGYTGD GFTCEVNPANPCAINTCDANARCVASAQDAYECSCLEGYTGDGFTCEVNPTNPCAINTCDANARCVASAQDAYECSCLEG YTGDGFTCEVNPANPCAINTCDVNARCVATAQDAYECSCLEGYTGDGFTCEVAVDPANPCAINTCDANARCVASAQDAYE CSCLEGYTGDGFTCNATDPCASNVCDPNARCVAFSPAIYECSCLEGYTGDGLTCEANTTDPCVNNACDMNARCVASAQDA YECSCLEGYSGDGFTCMANTTDPCVNNACDTNARCVASAQDAYECYCFEGYTGDGFTCEAEQINFCANNNCDRNARCVPT QTGYQCFCNQGYEGDGYSCRATQIDRCANNACDVNAYCVSTASAYNCYCNDGFSGDGFVCREIVDPCANNNCDVNARCVP SQSGYQCYCNQGFNGDGFTCQAVSVDLCYNNRCDFNAECSPAQDGGYSCTCNQGYEGDGFTCRNTLVNLCSACDASAQCI PEGRGFRCVCRSGFQGNGLVCEDIDECSQSGAACHRYATCYNVRGSFSCYCQPGYEGDGFSCQEVTQPELDDGALIYARG MAVMRVPLNANKPGNKIVFRSGQTIVGLGYDCQEEYIYWTDVSGRTISRAKADGSSTEVLISRGLSSPEGVAVDWLSRNM YWTDSGYDRIEVANLDGSNRRVLLKTDMINPRAIAVDPIGGLMYWTDWNRDAPKIERANMDGSERSVLVDSNLGLPNGLS LDYTTSQICWTDAGTKRIECMNMNGDPLTRFTVLPNSNYPFSIASYGFKLYWSDWETKSIQTISKTGGSESTDLKLPRGG NGRIYSVTAITSCPSTSNACSSNNGGCSSLCLPTQGGQRYCACPTNLEGNEVPCV >XP_031557799.1 nidogen-like [Actinia tenebrosa] MASRNLVFLLVLLVIQSSCLVLGARIQEFYPDGIDGPRGSSELLARRISPPVTLGTTYNLYGKPYTSLRVYKNGLITLGE EPISFSPQKHRKFLFPPEAKVIAPFYGQGDFTNTSRISYGETRDSDILTRASKDVKQSFSGEDEFNASAVFIVTWCQVKH AQHSQHKKNNTFQAVLVTNGDQTFVIFNYLTRGLQWAKGYHSQWKGAKYAYAQVGFSAGDFVRYSTLPGSGTNQVHWLAS KSNMNTPGRWIYKVGWPGMHGNEVQSADSFEIDDSTNTDFFAAQFYDGCFVVHGYLTANRSQIWKDVSIRSCIALCFERR QKYAALHNGSQCACLNDIRHLIKTNTDQDCDMACSVNDDEVCGGQMTASVYQSVGLAAVQSDQSGGQRKRKDVDECAVGV VSCHANATCINKSPGYCCQCNEGFYGNGITCIEIGAVQRMVGFLSGTVNGEEFISLNMDTIAFSDDGRAYVSVRAFPPYL AHSARVLTPLTDVVGWMYAKPKPSGFYNGYNVVGARFVRRASLRFDSGEELAILQKYQGRDVLSHYMKVETTMNGAIPRI HPKAEVRMRKFRQEFQRTAAGRVQSRGTVKYQVDGREHYFTVDQFIDYDEQKRCGQHVVRGVLEADVLTSNYDPAQAFLG IAVKGTFINTTLDSIDVQSQEADKMCGSKKVTCHTRGVCIQYRGDKECRCNHGYLGDGVTYCDDADECKLGRYRCAPDAD CVNTVGSYRCVCKKGYVGDGKTCQKDSVIQCPRPCGANAKCVKIALGLLCNCNPDYQGDGFDCKPDGTCAGIKCDPNAKC ATSSDKSRKCVCNDGYQGDGQTCTALEGRCGGVVCSTNAQCVQSKCVCNPGFQGNGKNCSDENECELKTHRCDTNADCIN TVGSYSCRCRLGYQGDGLSCQKASASCGGEKCHRFAYCDVDPQTKKQQCKCRRGFRGNGAECLDFNECIPILKTCDVNAL CRNTLGSYECICKRGFIQGSDDDKTCIVDDRCNGIKCDVNARCDRVQGCTCKTGFVGDGKTCNDIDECKSEMTRCDPNAD CRNTAGSFTCSCRSGFEGDGVRCRVDNSCDGVVCNVNARCEVQPDGRTRRCVCSNGWQGNGTLCTDVDECQSSRFSCPPN TDCINSNGSYECRCKRGFEKKGSSCVEDDSCGGVTCDAKARCVQTPQGTRQCVCNTGWQKNGNRCIDKDECQTNPCHPNA DCINSIGSFSCRCKPGYNGNGQACNDVDECQSGQSRCPANTDCINREGSYECRCTTGFVSNGSSCIVDESCGGVKCDPNA KCIQIAQGVRQCVCNAGWEKNGNTCIDVDECRASISPCHSNANCINSIGSFSCRCRPGFKGDGQFCEDDGTCGGVQCHPD ASCHKNTAEGTRCVCKPGYLGDGRKCADIDECIQGKDECHEHATCTNSAGSYKCSCNLGYVGDGFNCTDDGSCQGIDCDP NAKCVASSPTDGNRTCVCNDGFSGNGELCRDVDECDLGHAKCHRKAECVNQVGSYRCRCIRGYVGDGKQCESDGTCEGKV CDFNADCVTTNTTRGIDKTCKCKDGFSGDGVICTDVDECIKDPCPPMSQCVNAFGTYVCQCKPGYKKSNGLCEKICTRCR NGGSCIGENECKCPKGYSGNVCQWYGEASLIYTKGNSVQRMSLPPRSNAIGLVYNHEGMVNVGLDYDCVEEYIYWTEVME GCIMRAKYDGTNRELVFQRSEVRSPEGLSVDWIGRNLYWTDSGLDVIEVSRLNGSNRKVLISNGLYDPRAILVDPPSGKM YWSDWTRRRPRIETADMDGTNRRVLVYDDLGLPNGLTLVQTTNELCYTDAGSWSIRCVDLAGLNVRKVLTRVTYPFGIAY FNRTLYWTDWNQNLIHRIGVESSTPDSSLATFVGKTGKIFDVKAVQPCPAKVPRNPCSDKNGGCLGLCLLKPHGGYTCSC PKGQFPVKDGNQTTCRGKCDDPLGMEKGLISDAQLTASSAWSNNPKRHGAHRARLNLDTWPAGWSTKKFDPKPWVQIDLG THTMVTGVATQGLGKSIGEWVKTYRVAYSDDGVTWYVLRNGGRKKIFVANSDSTTVKRNKFPAALKTRWLRILPRTWHNH VSMRLELYGC >XP_039259166.1 nidogen-like [Styela clava] MKTVAVLLAVFAVGQSAVFNDFYPFDRENDHRVPKGDNTSSPQFELDLPIIFYDSVYNGIKVNADGFVTLGVVEHEIEEH LLEPVLVPFGFNLNNTDASEIYYQEHKDEATLSRATNDIQKAFVETAEAFVAKSAFIVTWVRLESPEHPGLTFTFQCVVV SNHLSSFAIFLYADDELAAGQSEEIRNQLIAKAGFSDKGGDQLESMTATELLEGGNAWSTGEWIFQIGGVLLSLEEEEEI PSHHLKAEPIHHRRESGFEVPEVNFNEDYGSDQQDCDSLECDPEFSTCTAFADGYCCQCSEGSFGNGYACIREDDDVRYN GQVDGYSIVMSDPWSNETAKGVDMHSYVVTKDGRAFSVMNGEISAKLYRALQPMAIFGTTLGWLFAQAEAPAINGFQYSG GKIVSETYIRYTTGQYEFRIRQEYDQVINDPEGGEGKVLNGRMTFSGRLPPVEEGENINVDDYTQIYKRTGADSIRSRDT RRYIVGDTEHIFTVDQSIRFEGCEASFEEVPADLAVDVSEVFLKFFPDENNLRFAVNSRIRPAEEVGVRPVEPSIIPDTP VPDTPVPDTPEPTPSETPVEKPEEPEIPEVVVTPATQTVCERQLQQVQQFQRENPGIVDEIFFPTCTDVGTFAPRQCLTY NSICWCVDEDTGEEIHGTRTEPLVGYQLDCSDVRAPPPAQTPCQEDRSNAETDRIVAGSEANSIFMPRCMESGAYEPVQQ LPDGSFMCVDFDGEEISRSTEMPNCLTPCQLAAYVAESSNIFLETNEFVVRCKADGDYNPEQCVETYCYCVDENGLEITN SRVETTFGEDVDLDCGKFNSKPVTSTVTTPTTTTGPIVGQEVRRLLFAQTMGINVIDLPVTRENSVSRRLFARSDQITIA LGYDCSSKKYYWTDVSKRRIYSSVLDGDGSRAQFLGDRLRSPEGISVDFLSGNVYWTDSEYDRIEVASADGSNRMTVVSG DIVNPRGIAVDPIRGRMYWTDWNRKAPKVWVANMDGSDRRVLLSEGLGLPNDITIDFYRQRVCFVDAGTFKVECMSLNGE GRETIYQMKQVPRPHPFGLAVDGDVLYYSSWGGSKVVHAVNWRTGDSIAIAGPRGAHGQMYGVEIAHSQCPRGYNYCSSN NGGCSHLCLPTPTGRECVCPPGAQDCQ >ACK77669.1 RE69505p [Drosophila melanogaster] MPTFGSKLLACLLLSSVILVSGQFEHYLDSLRASELYEFEDGSLGSIHLLPKGDSETIVLQLEQPIHFYGEQYEQLYINT NGILTFNSEFPEYLNQPFPLEYASIAAFYSNVDTSFSDEGTSISLFESKEQSILDRASSLVRYAFSSQSEFEARQVIVAT WRNVGYFDSKTDRLNTFQVALIANEQSTFVQFIYPDGGLNWLQGETAGLGLPDIRAQAGFVAEDGRFYTLNGSGSENARF LSESTNLGVPGVWLFEVAPIENEQNVRSPDNAESLTESPALALSCQAHAHQCHEKAECHDKAEGYCCVCGSGFYGNGKSC LANDQPIRVTGTLTGELNKQPVSEEAKLQSYVVTSEGRTYTTINPLTPELGAQLRLVLPLLTTVPWLFAKSVGGVANGYQ LTGGVYTHVSRLQFDSGENLHVNQTFEGLNYWDQLSVKIEIYGEVPAVAADAVLILPDYVEEYTFERPGELKSVQVLNIN ITEEQRVLGLQVEQRILYRSCLRDDEADPSATKVLQKISKVALDYVERDQALRIGAMSKVGVTPESNACNDGTADCVENS VCVPYEDTYRCDCYHGFAAQLDERGVEVCLDIDECATGSHVCDENAVCDNTEGGFNCYCTEGFEGNGYRCLSNSTADNIE YPPAVEGQAEPTSEPSPNPSPYPDQGQDQEREREDDQYPQPNPYPYPEEQIPQHPDECYRCSKDADCYQGRCTCHEGFDG DGYTCTNICGHGEVWENGRCEPLLLERHDVDPLCDALGECRCPYGYELSEDSQRCTYVQEFDGERNADLIPCDVDENCHI NATCNWYGQELRHICTCQPGFRGDGYNCDPISDDSCAIRPDICDVHADCVYEEHLGKSECQCQAGYTGNGFNCQLAAECQ SAEHCGENAFCDDGVCRCQADFERDVSDRCVPAGRCGSVFCGSNAICKWDSAEGVQYCDCLDGYQGDALTGCTSKPLSCH VLNNCGIHATCEPTEDPASYECQCIAGFKGDGYVCIEEQNCLNNPTLCDMNAQCRSTNSGLVCVCNQGFFGNGSLCQERQ HQDSDFLIVSQGVMIARVPLNGRNVRPISVAQMAIGLDKDCVEGRVYWGDISTKKIVSTKYDGTDLRPFITTDIESPEGI AIDVISRRLYWADSAKDTIEVASLDDPSLRAVIINKQLVNPRGIAVDPYREKLFWSDWDRESPKIEMSNLDGTGRELLLG KDDVTLPNSLVVLENSGEVCYADAGTKKVECIEPQNRQIRTISNELSYPFGITFTHDQFYWTDWTTKKVEIVDSLGARQT PIQPPFFGSHKMYGMTVVEQHCPQYQSPCQISNGGCTDSRLCLVNRQAPSGKSCKCTSASTGCTVLAPGY >KAG9432604.1 nidogen-2 [Apis mellifera carnica] MTRRACRLSVSWPALVLATLVIAPFAVALNKNDLYPYSIPGTSILQTDPNGLLLSAETILKTPIAFYDQIFNSIFVNGNG VLSFARAMHRFFNIAFPLDDPVIAPLYTHVDTRGSGRVYYGETDAPEILARAGGMVRSAFTDAADFVPTHAFLATWVDVG YYNGKSDKVNTYQVAISSNGTHSYVELLYPDDGIQWIQGESHPNGLPDAKAQAGLMSEGRMYTLRGSGTDQIQNVDKWSN VNRPGQWVFQVGPISDEEDIKVPDNVEDSSATNEVANCRTGATACHSKATCVDYEVGFCCHCKQGFFGNGKSCQPNDVPL RVNGRISGTINGVEFLARDLQCYVQTKDGRTYTALSRVPEEIGASFQLLGNLGGVIGWLFAKPIGETKNGYELTGGLFNH TAELTFPSTGDKVTIRSNYLGLDVFGQLKMQAQIEGTLPQLGRDTGLDYGDYDELYTRVQTGVIRSRAERVCKLAEGVES RELDFVQDETIYYNECPYLTVEPEDDTTRLKFFRGVTTYEATEGIIRFAVNTKVAPLEEEDPCIQGRETCGDHSYCVVDG DSFKCVCNPGYQYLYEEDGSAICIDVNECTAGKHMCSPDAQCINQEGSHTCQCRPGFSGDGRTCDKLPSCEDTRCDNYEQ CVMIEGAPNCICLPGFEDTEQGCYPATQRAPCDVEDNCSPNGFCNIDAEKQKYVCVCLPGFIGDGYTCYPDAEVTTTDEP PKPQCIEEMCWCSSGWEYRNNECVRQEEETRTADYDRDLSARPLPECYEDNCICPWGHNYDRSKEICVPRPGYKHETMGP SGVHLSCNVMNRCHPYAQCIYVTSTADYECRCNQGYEGDGMECIKTEVSCLEVDICDPNASCQQEESLAKCVCNPGFEGD GTMCSPIDECSSSSYCLENERCLYNSASSRYECTCNPGYSMVDSRCVVSDCSTNPSQCHVNAQCTSIGEGGYRCVCAEGY NGDGIRQCVEDHIGCNVLNNCGRNAVCGYNQTSANFVCVCQQGYYGDGFTCLPQSSCRHDPAICSPDATCVAAGENQYAC VCNEGFVGDGTNCKSRPKHEANFLLVNQGMATLRIPFAPTYEDPGSPIYIAYMQMAIAIDIDCMNGKAYSSDISGNRIIE LTYNGSMAETFLPKVSNPEGLAIDWVSRNIFWTGKTTVEVANLETKKRKVLVSDGLVNPRGIAVHPYRGKIFWSDWNRAS PKLEWANEDGTDRAIFLQGDYVKLPNSLSIDWAMDELCWADAGTFTISCMEIDSRKINVVANQLTYPFGLAISQQHYYWT DWKTHKIEVAMKSTGDRKQAISVPPGGSGKLYGIVVVPESCPRVTNACQFEGGRCSKDQLCLPNGQNGRSCVCADDADGP CTDNL >CAE1252257.1 LRP4 [Sepia pharaonis] MCRSPPPPNKKAIPSCISSSPDEAGNKQGMKAIVTIIIAFGYFYVLNATNCQCPENMFNCGDSKCTCIQQSWVCDEDQDC VNRNDEKYCKHPSCSSLQFTCSNHKCIKKDWQCDGDNDCGDDSDELDCMTKNCTDEEFRCDNGRCILVQWKCDGDDDCKD GSDEHCDQEECSQTDIRCGDGKCIPKAWICDEEVDCLDQIDEINCEFRKITCKSDEMYCPGSRRCIRARLKCDGQNDCGD WEDEIDCGNATLCHKGEFRCENGACINGTWRCDGEFDCHEKSDEFDCPLPSCSPRKFQCHTGHCIESSWHCDGHADCDDG SDEANCDIENCSSGQFQCRSGKCIGSNKVCNGLSECPDGSDEMHCNLPPSCRENNGGCNQNCLQTSRGARCSCYMGYHLQ RDGKTCIDFNECEMVGACSQVCTNHPGSYKCSCATGYILKPDGRGCKATGGEVNLIFANRIEIRKGNPSKSEFSFILDNL DNAIALDFHYDLGLLFWSDVSLDVIKRVYLNGSNIQTIVECGLKNTGGLAVDWIHDKLFWTDSGTSRIEVTELDGADRRV LVWKGIDKPRAIVAHPGKGMIFWTDWGSSPKIESSGMDGHERRTIVNSSLIWPNGLTIDYAAGKLYWADAKYHVIECAYL DGSYRRTIISHGLPHPFALTLFEDELYWTDWHTRSIWRANKFTGNRVERVRSRLHYPMDIHTYHPLRQPQAMNRCGSDNG GCSHLCLPTKRNYICACPTGLALRKDGKTCRDRLDNFLLFSTKSDLRRISFDTAEMIDMIIPLPNVQNVVAVEWDSDTNT ILWTDVSTDTINRAKWDGSQAEVLIDSSLDSPAGLAVDWVGNKIYWTDQGTNVIEVANSDGLFRKVLIWENLDKPRDIVL EPYARYLFWTNWGHEPKIERAGMDGNGRTVLVSSNLTLPNGLSVDVKSSRLYWTDAGTQTIESATFDGLYRRIVIGVGLP HPFGLIVYEDSIFWTDWNTKSVQMASKFNGTNHQTLKKGLDNVMDITVFHRGRPYLSTPCRKGNGGCSHLCLLAPGPKTH TCACPTGILIKPDGKTCEKEMKNFLIFTRRNDIRKISMDVDYFADVVVPLGHLKNAVALDIDPLQGMIYWSDTVVDKIQR SNLDGSQVEDVISHGLDTTDGLAVDYIGKKIYWTENGNNRIEVANLDGTMRKVLFWQNLDSPRAIVLHYEAGYMYWTDWG NQPRIERADMDGNNRLTVIANDLGWPNGLTIDKETRRLIWNDATTEVIECSDLNGNFRKVLVSKLLHPYGLTVAGRYIFW TDWRTRSIHRADKITGEDVTVIRSNIPGLMDLRAVYIDKTDHPSNRCGQSNGGCSHLCLPNPQGYSCVCPTGLLLTQDGK TCQSMPSVYLLFASRGSIRRISLDSHDYTDVYIPLPDVHNAVALDFDIQESKIYYTDVTLDVIRRASLNGSNMEEVIHKG LSTTDGLAVDWVARNIYWTDTGRDVIEVARIDGTSRRTLVSENLDEPRAVAVFPKKGFMFWTDWGKSPKIERAYLDGTSR KAIVTNDLGYPNGLSIDYVTKHLYWVDAQLDKIEMSDLNGKNRIEIIRDVPHPFGLSVFGDYIYWTDWRTKSIHRANKMT GLNRIVIQNNMEGLMAISVVSPLRQTGTNQCAIRNGGCTHLCLARPNGYKCACPTYPDSRPCLVVPLISSSNDDDLFAKK SSSTQGSHQSNRCNKSQIKAGLCQPEDGHEAESRHFSTFVIPGVLSSAVIIGFIFILVMWKRQRRRSAPEFITLTFTNPS YQRTSTETIDTERQSHGSSSWRLFRFDRAEEQLLMLPQNDEKLNNLDQVQCDRPDIPENNAHVALKAEKHCRKVLLTLPK KITNTTKTNLDFSSS >XP_546076.2 nidogen-1 [Canis lupus familiaris] MSAARRRGETAWTRALLLQLLLVGPGGCLSRQELFPFGPGHGDLQLEPGDDRVSPALELRRALRFFDKSD IDSVYVTTNGIIAMSEPPAKESYPGVFPPTFGVVAPFLADLDTTDGLGKVYYREDLSPSVTQLAAECVQR GFPEVSFQPSSVVVVTWESVAPYQGPSKDPEQEGKRNTFQAVLASSDYSSYAIFLYPEDGLQFYTTFSKK DENQVPAVVAFSQGIQGLFWKSEGAYNIFANDRESIGNLAKSSNSGQQGVWVFEIGSPATASGVVPSDVS LGLDDGAEYDDEDYESVTHLGLGDVSTTPFPYEDPRRGDPGTYSAPRVLSPRRLPTERHPGPPTERTRSF QPPAETFPQQHAQVIDVDEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDFATGFCCSCVAGYTGNGR QCVAEGSPQRVNGKVKGRIFVGNSPVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGI IGWMFAVEQDAFKNGFSITGGEFTRQAEVTFVGYPGKLVIKQQFSGIDEHGHLTINTELEGHVPHIPFGS SVHIEPYTELYHYSRGVITSSSTREYTVTEPEQGGAASSNIYTYQWRQTITFQECAHDTSRPVLPSTQQL SVDSVFVLYNQEERILRYALSNSIGPVRDGSPDALQNPCYIGTHGCDTNAACRPGPGVQFTCECSIGFRG DGRTCSDIDECSEQPSVCGSHAICNNHPGTFRCECVEGYQFSEEGTCVATVDQRPINYCETGLHDCDIPQ RAQCIYMGGSSYTCSCLPGFSGDGRACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYHGDGFHCVPGE MEKTRCQLEREHILRAAGLTDPQQPVMPGLFVPECDEHGHYTPTQCHGSTGHCWCVDRDGRELEGTRTRP GMTPPCLSTVAPPIHHGPSVPTAVIPLPPGTHLLFAQTGKIEHLPLEGSIMQKTEAKTLLHAPDKVIIGL AFDCVDKMVYWTDISEPSIGRASMHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSHLDRIEVAKLDGT QRRVLFETDLVNPRGIITDSVRGNLYWTDWNRDSPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQL CWVDAGTNRVECLKPDESGRRRVLEGLQYPFAVTSYGKNLYYTDWKTNSVVAVDLAISKETDAFHPHKQT RLYGVTTALSQCPQGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIERK >NP_001094625.1 nidogen-1 precursor [Bos taurus] MLATVRRSGAAWTRALLLQLLLAGPGGCLSRQELFPFGPEHGDLELEAGDDLVSPALELSTALHFFDRSD IDSVYVTTNGIIAMSEPPAKETHPGPFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSVTQLAAECVQR GFPEVSFKPSSAVVVTWESVAPYQGPSKDPTLEGKRNTFQSILASSDSSTYAIFLYPEDGLQFYTTFSKK EENQVPAVVAFSQGLVGLIWKSDGAYNIFANDKESIGNLAKSSNSGLQGIWVFEIGSPATASGVVPADVN LGLDDGTEYDDEDYDSVTRVGLEDAVTTSFPYEAPGRGDSGTYNTPSDLSPRRMATERPLTPPTEKTRSF QLPGERFPQQQPQVIDVDEVEETEIVFRYNTDSRQTCANNRHQCSVHAECRDFATGFCCRCVAGYTGNGR QCVAEGSPQRVNGKVKGRIFVGDSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGI IGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHRDKLIIKQQFSGIDEHGHLTIDTELEGRVPQIAFGS SVHIEPYTELYHYSRQVITSFSTREYTVTEPERHGTAPSHAHTYRWRQTITFRECLHDDSRPALPSTQQL SVDSVFVLYNQEERILRYALSNSIGPVRDGSPDALQNPCYIGSHGCDSNAACRPGPGTQFTCECSIGFRG DGRTCYDIDECSEQPSVCGNHAICNNHPGTFRCECVEGYQFSEAGTCVAAVGLRPVNHCETGLHDCDIPQ RARCIYMGGSSYTCSCLPGFSGDGRACQDVDECQPSRCHPDAFCYNTPGSFTCRCKSGYQGDGFHCVPGV VEKTRCQHEREHILGTADSSRPRPPGLFVPECDEHGQYVPTQCHSSTGYCWCVDRDGREVQGTRTRSGMR PPCLSTVAPPVHYGPPVPTTVIPLPPGTHLLFAQTGKIERLPLEGSTMTKSEAKTLLHAPGKVIIGLAFD CVDKMVYWTDISQPSIGRASLHGGEPATIVRQDLGSPEGIALDHLGRNIFWTDSQLDRIEVAKLDGTQRR VLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCWV DAGAHRAECLKPGQSSRRKVLEGLQYPFAVTSFGKNLYYTDWKTNSVVAVDLAVSKETDSFHPHKQTRLY GITSALSQCPEGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIERK >XP_017203089.1 PREDICTED: nidogen-1 [Oryctolagus cuniculus] MRAAWMRALLLQLLLAGPGGCLSRQELFPFGPGQGDLELEDGDDLVSPALELSGALHFYDRSDIDSVYVT TNGIIAMSEPLAKESHPGLFPPGFGVVTPFLVDLDTTDGLRKVYYREDLSPSIMQLAAECVQRGFPEVSF QPSSVVVVTWESVAAYQGPNQDPIQEGKVSTCPGTSSSHLTHCALCSFGLKYPYAPYACVIDKHETQSRI LFSKAVEICFSDDQTECRDYATGFCCSCVAGYTGNGKQCVAEGSPQRVNGKVKGRIFVGTSQVPVVFENT DLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVG YPGKLVIKQQFSGIDEHGHLTIDTELEGRVPQIPFGSSVHIEPYTELYHYSSSVITSSSTREYTVTEPER DGTAPSHTYTYQWRQTITFQECVHDDSRPALASTQQLSVDSVFVLYNQEEQILRYALSNSIGPVRDGSPD ALQNPCYIGTHGCDTNAACRPGPGTQFTCECSIGFRGDGKTCYDIDECVEQPSVCGSHALCNNHPGTFRC ECVEGYRFSDQGTCVAIMDQRPINYCVTGLHDCDIPQRAQCVYTGGSSYTCSCLPGFSGDGRACQDVDEC QPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCIPGELEKTRCQLEREHILGAAGAADAQRPRPPGLFVP ECDEHGHYSPTQCHGSTGYCWCVDRDGREVEGTRTRPGMRPPCLSTVAPPIHQRPLVPTAVIPLPPGTHL LFAQTGKIENVPLDGNTMKKTEAKALLHMPDKVIIGLAFDCVDKMVYWTDISEPSIGRASLHGGEPSTII RQDLGSPEGIAVDHLGRNIFWTDSQLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRD NPKIETSYMDGTNRRILVQDDLGLPNGLTFDAFSSQLCWVDAGTNRAECLHPSQPSRRKVLEGLQYPFAV TSYGKNLYYTDWKTNSVVAVDLAVSKETDSFHPHKQTRLYGITTALSQCPQGHNYCSVNNGGCTHLCLAT PGSRTCRCPDNTMGVDCIERK >XP_024106979.1 nidogen-1 [Pongo abelii] MLASRSRIRAAWTRALLLPLLLAGPVGCLSRQELFPFGPEQGDLELEDGDDLVSPALELSGALRFYDRSD IDSVYVTTNGIIATSEPPAKESHPGLFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSITQRAAECVHR GFPEISFQPSSAVVVTWESMAPYQGPSRDPDQEGKRNTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKK ENNQVPAVVAFSQGSVGFLWKSNGAYNIFANDRESIENLAKSSNSGQQGVWVFEIGSPATTNGVVPADVI LGTEDGAEYDDEDEDYDLATTRLGLEDVGTTPFSYKALRRGGADTYSVPSILSPRRAATERPLGPPTERT RSFQLAVETFHQQHPQVIDVDEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTG NGRQCVAEGSPQRVNGKVKGRIFVGSSQIPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPV GGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGIDEHGHLTIDTELEGRVPQIP FGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPSHIYTYQWRQTITFQECVHDDSRPALPST QQLSVDSVFVLYNQEERILRYALSNSIGPVREGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIG FRGDGRTCYDIDECSEQPSVCGSHAICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCD IPQRARCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV PGEVEKTRCQHEREHILGAAGAADPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTR TRPGMTPPCLSTVAPPIHQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLEGNTMRKTEAKAFLHVPAKVV IGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAKL DGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDVFS SQLCWVDAGTNRAECLNPSQPSRRKVLEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAVSRETDAFQPH KQTRLYGITTALSQCPQGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIERK >XP_020929417.1 nidogen-1 isoform X1 [Sus scrofa] MLAAIRWSQAAWTLALLLQLLLAGPGGCLSHQELFPFGPGHGDLELEAGDDLVSPALELSTALRFFDKSN IHSIYVTTNGLIATSEPPAKEAHPGLFPPTFGAVAPFLADLDTTDGLGKVYYREDVSPSTTQLAMECVQR GFPEVTFKPSSVVVVTWENVAPYQGPGKDPAQEDKRNTFQAVLASSDASSYAIFLYPEDGLQFYTTFSKK DEDQVPAVVAFSQGVVGLIWKSDGAYNIFANDRESLGNLAKSSNSGQQGVWVFEIGSPATASGVVPSDVN LGLDDGTEYDDEDYDSVTGVGLEVVGTTSFPHETPRRGDAGTYNMPSDLAPRRLATERPPTPPTERTRSF QLPAETFPQQQPQVIDVDEVEETGVVFSYNTDNRQTCANNRHQCSVHAECRDFATGFCCSCVAGYTGNGR QCVAEGSPQRVNGKVKGRIFVGNSPAPIVFENTDLHSYVVMNHGRSYTAISTIPETIGYSLLPLAPIGGI IGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPDKLVIKQQFSGIDEHGHLTIDTELEGRVPHIPFGS SVHIEPYTELYHYSRQVITSSSTREYTVMEPEQDSTAPSHVHTYQWRQTITFQECVHDDSRPALPSTQQL SVDSVFVLYNQEERILRYALSNSIGPVRDGSPDALQNPCYIGTHGCDTNAACRPGPGTQFTCECSIGFRG DGRTCYDINECSEQPAVCGSHAICNNHPGTFRCECVEGYRFSEEGTCVAVVDQRPINYCETGLHDCDIPE RAQCIYLGGALYTCSCLPGFSGDGRACQDVDECQPSRCHPDAFCYNTPGSFMCQCKPGYQGDGFRCVPGA EVEKTRCQLEREHLLGPADAQRPWPPGLFVPECDEHGHYAPTQCHGSTGYCWCVDRDGREVEGTRTRPGM RPPCLSTVAPPIHHGPAVPTAVIPLPPGTHLLFAQTGKIERLPLAGSTMTKTDAKALLHAPDKVIIGLAF DCVDQMVYWTDISEPSIGRASLHGGEPTTILRQDLGSPEGIALDHLGRNIFWTDSHLDRIEVAKLDGTQR RVLFDTDLVNPRGIVTDSVRGNLYWTDWNRDSPKIETSYMDGTNRRVLVQDDLGLPNGLTFDAYSSQLCW VDAGTSRAECLKPGQPSRRKVLEGLQYPFAVTSYGKNLYYTDWKMNSVVAIDLAVSKETDTFHPHKQARL YGITTALSQCPEGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIEQK >XP_031408053.1 LOW QUALITY PROTEIN: nidogen-1 [Meleagris gallopavo] MSAVRRRAPCGRPASRCAPSTPRFPSYRSCSQHQREGRAGGCRQTPPRLRTPALWCERRRRLMRAGLEVL ATVATNGIIAVNEPKNEENYLGQFPVSFGAIAPFMADLDTTDGRGSVYYREDSSSDVLQLASDYIKGGFP EAAFDPSSVVIVTWKLVAPYQGPGEDLTLEEKRNTFQAVLASSDSSSYAIFLYPEDGLQFYSAYSKNNDG KIPAMVGFSQASTNYYFWENPGSYNVIANDEDSIRNLHKSSNAGRQGVWVFEIGSSSDTIVPAKVSNVLA SLEPSEEDQELTSKPFMSDYGSTEIRPQYVTSSTDSTEEDQHVTYSVPQLAVEDFITSYQDVTGTPSTES FYRHREFPTAKAPPRQFPAQQFPPQGPQVIDVEEFDETGIVFRYHTDVQQTCANNRHQCSVHAICKDYPN GFCCSCIAGYKGNGRQCVAEGSPQRVNGKVKGRIFVGNNPVPVTFENTDLHSYVVMNHGRAYTAISTIPE ALGYSLLPLASIGGVIGWMFAVEQQGYKNGFSITGGEFTRQTEVTFLGNNEKVVIKQKFSGIDEHGHLTI STEMEGRVPEVPAGASVHIEPYTELYHASSSVITSSSTREYTVTEPERDGVASTYTGAYQWRQTISFDEC IHDDTLHAAPATQQLSVDSIFVLYNRDEQILRYAMSNSIGPISDGSADISRNPCYTGTHNCDTNAVCRAG SGNRFSCECSIGFRGDGNVCYDIDECSEQAGACGSNAVCNNQPGTYRCECVDGYQFAADGRTCVAVEYAV NHCQTGTHGCDIPQRAQCVYTGGSAYVCTCLPGFSGDGRACEDIDECQQGRCHPDAFCYNTPGSFSCQCK AGYRGDGFQCVLGGVVKTKCQREKEVALGSGGTFFQREIRVGQFIPQCDEHGNYVPTQCHGSTGYCWCVD RDGNEIDGTRSXPGVRPPCLSTAAPPVVIGPSVRPDTIPLPPGTHLLFAQSGKIEHVPLEGNSMKKNGAK ALLHIPDKVIIGVAYDCMDKMVYWTDISGPSISRASLHGGEPTTIIRTDLGSPEGIALDHLGRNIFWTDS QLDRIEVARLDGRQRRILFDTGLVNPRAIVVDPVRGNLYWTDWNREAPKIETSYMDGTNRRILVKDDLGL PNGLTFDPYSSMLCWVDAGTKRLECMNPNQLGRRKIVEGIQYPFGVTSYGKNLYYTDWRRDAVVAVDRMV SVENDNFQPHKRSRLYGITTAFAQCPGGHNYCTVNNGGCTHLCLATPEGRSCRCPDNTVGVDCIERN >XP_003824554.1 nidogen-1 [Pan paniscus] MLASSSRIRAAWTRALLLPLLLAGPVGCLSRQELFPFGPGQGDLELEDGDDLVSPALELSGALRFYDRSD IDSVYVTTNGIIATSEPPAKESHPGLFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSITQRAAECVHR GFPEISFQPSSAVVVTWESVAPYQGPSRDPDQKGKRNTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKK ENNQVPAVVAFSQGSVGFLWKSNGAYNIFANDRESIENLAKSSNSGQQGVWVFEIGSPATTNGVVPADVI LGTEDGAEYDDEDEDYDLATTRLGLEDVGTTPFSYKALRRGGADTYSVPSVLSPRRAATERPLGPPTERT RSFQLAVETFHQQQPQVIDVDEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTG NGRQCVAEGSPQRVNGKVKGRIFVGSSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPV GGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGIDEHGHLTIDTELEGRVPQIP FGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPSHIYTYQWRQTITFQECVHDDSRPALPST QQLSVDSVFVLYNQEEKILRYALSNSIGPVREGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIG FRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCD IPQRARCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV PGEVEKTRCQHEREHILGAAGAADPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTR TRPGMTPPCLSTVAPPIQQGPALPTAVIPLPPGTHLLFAQTGKIERLPLEGNTMRKTEAKAFLHVPAKVI IGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAKL DGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDVFS SQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAFQPH KQTRLYGITTALSQCPRGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIERK >XP_003993948.1 nidogen-1 [Felis catus] MLAAIRRSGAAWTRALLLQLLLAGPGGCLSRQELFPFGPGHGDLELEAGDDQVSPALELRRALRFFDKSD INSVYVTTNGIIAMSEPPAKESSPGLFPPTFGVVAPFLADLDTTDGFGKVYYREDLSPSVTRLAAECVQR GFPEISFQPSSAVVVTWESVAPYQGPSKDPAQEGKRNTFQAVLASSDSSSYAIFLYPEDGLQFDTTFSKK DETQVPAVVAFSQGVQGFIWKSDGAYNIFANDRESIGNLAKSSNSGQQGVWVFEIGSPATASGVVPSDVS LGLDDGAEYDDEDYDSVTHLGLEDVGTTSFPYEAPRSGDPSMHSVPWVLSPRRLPTERPPGPPGPPTERT RSFQLPGERFHQQHPQVIDVDEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDFATGFCCSCVAGYTG NGRQCVAEGSPQRVNGKVRGRILVGNSPVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPV GGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGYPGKLVIKQRFSGIDEHGHLTITTELEGRVPQIP FGSSVHIEPYTELYHYSPGVITSSSTREYTVMEPEQDGAAPSTIYTYQWRQTITFQECAHDTSRLALPNT QQLSVDSVFVLYNQEESILRYALSNSIGPVKDGSPDALQNPCYIGTHGCDTNAACRPGPGVQFACECSIG FRGDGRTCSDIDECSEQPSVCGSHAICNNHPGTFRCECVEGYQFSEEGTCVAVVDQRPINYCTTGLHDCD IPQRAQCIYMGGSSYTCSCLPGFSGDGRACRDMDECQPSQCHPDAFCYNTPGSFTCQCKPGYRGDGFHCV PGEMEKTRCQLEREHILGAAGAADPPRPGLFVPECDEHGHYVPTQCHGSTGYCWCVDRDGRELEGTRTRP GMRPPCLSTVAPPIHHGPSVPTAVIPLPPGTHLLFAQTGKIERLPLEGSTMQKSEAKTLLHAPDKVIIGL AFDCVDKMVYWTDISEPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSHLDRIEVAKLDGT QRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRESPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSAQL CWVDAGTSRVECLKPGQPSRRKVLEGLQYPFAVTSYGKHLYYTDWKMSSVVAVDLAISKETDTFHPHKQT RLYGVTTALSQCPQGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIERK >XP_011960995.3 nidogen-1 [Ovis aries] MLATVRRSGAAWTRALLLQLLLAGPGGCLSRQELFPFGPEHGDLELEAGDDLVSPALELSTALHFFDRSD IDSVYVTTNGIIAMSEPPAKETHPGPFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSVTQLAAECVQR GFPEVSFKPSSAVVVTWESVAPYQGPSKDPTLEGKRNTFQCILASSDSSTYAIFLYPEDGLQFYTAFSKK EENQVPAVVAFSQGLTGLIWKSDGAYNIFANDRESVGNLAKSSNSGLQGIWVFEIGSPATASGVIPADVN LELDDGAEYDDEDYDSVTHLGLEDAVTTSFPYEAPRREDSGTHNTPSDLSPRRMATERPLTPPTEKTRSF QLPGERFPQQQPQVIDVDEVEETGIVFSYNTDSRQTCTNNRHQCSVHAQCRDFATGFCCSCVAGYTGNGR QCVAEGSPQRVNGKVKGRIFVGDSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGI IGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPDKLTIKQQFSGIDEHGHLTIDTELEGRVPQIAFGS SVHIEPYTELYHYSRQVITSSSTREYTVTEPEQHGTAPSHVHTYQWRQTITFQECVHDDSRPVLPSTQQL SVDSVFVLYNQEERILRYALSNSIGPVRDGSPDALQNPCYIGSHGCDANAACRPGPGTQFTCECSIGFRG DGRTCYDIDECSEQPSVCGNHAVCNNHPGTFRCECVEGYRFSEAGTCVADVDLRPINHCETGLHDCDIPQ RAQCKFMGHGSYTCICLPGFSGDGRACQDVNECQPSRCHPDAFCYNTPGSFVCRCKYGYQGDGFHCVPGE VEKTRCQQERERVVGTADSPRPQPPGLFVPECDEQGHYVPTQCHSSTGYCWCVDRDGQEVEGTRTGSGMR PPCLSTVAPPVHFGPPVLTAVIPPPPGTHLLFAQTGKIERLPLEGSTMTKSEAKTLLHAPDKVIIGLAFD CVDKMIYWTDISQPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSQLDRIEVAKLDGTQRR VLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCWV DAGTHRAECLNPGQPNIRKVLEGLQYPFAVTSFGKNLYYTDWKTNSVVAVDLAVSKEMDSFHPHKQTRLY GITSALSQCPEGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIEQK >XP_018887566.2 nidogen-1 [Gorilla gorilla gorilla] MLASSSRIRAAWTRALLLPLLLAGPVGCLSRQELFPFGPGQGDLELEDGDDLVSPALELSGALRFYDRSD IDSVYVTTNGIIATSEPPAKESHPGLFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSITQRAAECVHR GFPEISFQPSSAVVVTWESVAPYQGPSRDPDQKGKRNTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKK EKNQVPAVVAFSQGSVGFLWKSNGAYNIFANDRESIENLAKSSNSGQQGVWVFEIGSPATTNGVVPADVI LGTEDGAEYDDEDEDYDLETTRLGLEDVGTTPFSYKALRRGGADTYSVPSVLSPRRAATERPLGPPTERT RSFQLAVETFHQQHPQVIDVDEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTG NGRQCVAEGSPQRVNGKVKGRIFVGSSQIPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPV GGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGIDEHGHLTIDTELEGRVPQIP FGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPSRIYTYQWRQTITFQECIHDDSRPALPST QQLSVDSVFVLYNQEERILRYALSNSIGPVREGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIG FRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCD IPQRARCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCV PGEVEKTRCQHEREHILGAAGAADPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTR TRPGMTPPCLSTVAPPIHQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLEGNTMRKTEAKAFLHVPAKVI IGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAKL DGTQRRVLFETDLVNPRGIVTDSVTGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAFS SQLCWVDAGTNRAECLNPSQPPRRKVLEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAFQPH KQTRLYGITTALSQCPQGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIERK >XP_004077531.1 nidogen-1 [Oryzias latipes] MFWRDQGWLLWATFLGLVASAHSIRRDEFFPFGESAGDQVLEPENDRTQRLDLSAPLLFYDRSFDSIFIN TNGFVATEEPPSESTYLGKMPPSFGMIAALHGDLDTSAGVGKVFFRQDSRADVLRRAAEHINRAFPYNDE VDPTHAVVVTWVDVAPHTPHTRGDGLEKKRNSFQLVLASLQKASYAILLYARDGVQFSSTLVQGSDVIVH AGFSKGQVPGFWFTSQGPYYRTTSDEEISVRELAEQTNSGQRGVWVYEIGTSPTFSNVVPGEVTDLPTEP PPPLAQTTEPSWPLYTEYDPEQIEIHSNQYQPLQPHDPEVVVLDETDINVDVFSYNFGTCSNNRNKCSQF ADCRDYSSGFCCHCRPGFYGNGIQCVAEGKPQRMNGKIHGRVFVGSSPYPVELGGVDLHSYVVVNDGRSY VAISDIPETLGPSLLPLSVLGGVIGWAFALEQPGYRNGFSIIGGEFTREAEVTFMPWNEKLIIRQEFKGT DELDHLVVKTTLEGKVPEMPLGSTVTMDPYAEIYQYGSNLITSSSTREYKVTMPDGSAETRTYQCRQTIT FQSCQHGDSLRDVKPSQMLSVDQVFVLYDVNNKILRYAMSNKVGDVNGGEPQQNPCFTGRHGCDNNAVCR PGQGSQFTCECAAGFLDNGRNCDDIDECRENPQICGYNAVCNNQPGTYRCECEDGFQFGSDGRTCVEVDR PVNHCEEGTHDCDAPERAQCSYTGSSSFICSCLPGFVGDGRNCQDIDECQSRRCHQDADCFNTPGSFVCR CRQGYRGDGSYCYSDRRRTRCEEERDSLLGGTVFGPRGPRPSESHIPACDGNGEYEPLQCDRRTGSCWCV DRNGVEVRGTRSAPGSTPMCIHDDGGPPDVRPTPRPDVDPLPPGTHLLFAQSGRIEHVPLESYEMRKEGA KAVLHLPERVIIGVAYDCVEKVVYWTDITSPAISKASIQGGEPTTVIRTDLGSPEGITVDHIGRTIFWTD SMKDRIEVASLDGSRRRVIVDSDLINPRAIVADPVHGHLYWTDWNREAPKIETSYMDGSNRRVLVQNDLG LPNGLTYDFQSSLLCWADAGTHKMECMHPDRGDRQSVMEGIQYPFGITSYGRKIFYTDWKRNAVVAMDRH SGRESDEFQPSKQTKLYGITSAYSQCPPGRNYCSVNNGGCTHLCLATPNGRSCKCPNNPATAACVERPAE Y >XP_021151656.1 nidogen-1 isoform X1 [Columba livia] MSRSLGGKNMIMIIIPNLTLHCKLPNKVATNGIIAVNEPSSEEKYLGQFPVSFGAIAPFMADLDTTDGRG NVYYREDSSSDVLQRASDYIRSGFPETTFDPSSVVIVTWKLVAPYQAPGEDHGLEEKRNTFQAVLASSDS SSYAIFLYPEDSLQFYSTYSKNNDEKIPAMVGFSQASTNYYFWEKPGSYNVIANDEDSIRNLHKSSNAGK QGVWVFEIGSSSDSIVPAKISDVLESLEFDEQDQEMTSKPFMSDYGSTEIRQQYVTSSTDSTEDDQHHIT YSVPQLAAEDFQTLYQDVTETPPTESFYGHQDFPTAKAPPRPFQVQQFPPQQPQVIDVEEFDETGIVFRY HTDVQQTCANNRHQCSVHAICTDYPNGFCCSCIAGYKGNGRQCVAEGSPQRVNGKVKGRIFVGNNPVPVT FENTDLHSYVVMNQGRAYTAISTIPETLGYSLLPLASIGGIIGWMFAVEQQGYKNGFSVTGGEFTRQTEV TFLGNNEKLVIKQRFSGIDEHGHLTISTEIEGRIPEIPSGASVHIEPYTELYHTSSSVITSSSTREYTVT EPERDGVASTYTGAYQWRQTISFDECIHDDSHHAASATQQLSVDSVFVLYNRDEQILRYAMSNSIGPISD GSADINRNPCYTGTHNCDTNAICRPGTGNRFLCECSIGFRGDGNVCYDVDECSEQPALCGNNAVCNNQPG TYRCECVEGYQFAADGRTCVAVDYAINHCQTGTHNCDIPQRAQCVYTGGSAYICTCLPGFSGDGRACEDV DECQQGHCHPDAFCYNTPGSFSCQCKAGYRGDGFRCVLGEAEKTKCQREREVALGSVGTFFPREIRVSHF IPQCDEHGNYLPTQCHSSSGYCWCVDRDGNEIDGTRSGPGVRPPCLSTAAPPVVIGPSVRPDTVPLPPGT HLLFAQSGKIEHVPLEGNNMKKNGAKALLHIPDKVVIGVAYDCTDKMVYWTDISGPSISRASLHGGEPTT IIKTDLGSPEGIAVDHLGRNIFWTDSQLDRIEVARLDGRQRRILFDTGLVNPRAIVVDPMRGNLYWTDWN REAPKIETSYMDGTNRRILVKDDLGLPNGLTFDPYSSMLCWVDAGTKRLECMNPNQLGRRKIVEGIQYPF SVTSYGKNLYYTDWRRDAVVAVDRTISIENDNFQPHKRSRLYGITTAFAQCPGGHNYCTVNNGGCTHLCL ATPGGRSCRCPDNTVGVDCIERN >XP_017897955.1 PREDICTED: nidogen-1 [Capra hircus] MLATVRRSGAAWTWALLLQLLLAGPGGCLSRQELFPFGPEHGDLELEAGDDLVSPALELSTALHFFDRSD IDSVYVTTNGIIAMSEPPAKETHPGPFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSVTQLAAECVQR GFPEISFKPSSAVVVTWESVAPYQGPSKDPTLEGKRNTFQCILASSDSSTYAIFLYPEDGLQFYTAFSKK EENQVPAVVAFSQGLTGLIWKSDGAYNIFANDRESVGNLAKSSNSGLQGIWVFEIGSPATASGVIPADVN LELDDEAEYDDEDYDSVTHLGLEDAVTTSFPYEAPRRGDSGTYNTPSDLSPRRMATERPLTPPTEKTRSF QLPGERFPQQQPQVIDVDEVEETGIVFSYNTDSRQTCTSNRHQCSVHAQCRDFATGFCCSCVAGYTGNGR QCVAEGSPQRVNGKVKGRIFVGDSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGI IGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPDKLTIKQQFSGIDEHGHLTIDTELEGRVPQIAFGS SVHIEPYTELYHYSRQVITSSSTREYTVTEPEQHGTAPSHVHTYQWRQTITFQECVHDDSRLVLPSTQQL SVDSVFVLYNQEERILRYALSNSIGPVRDGSPDALQNPCYIGSHGCDANAACRPGPGTQFTCECSIGFRG DGRTCYDIDECSEQPSVCGNHAVCNNHPGTFRCECVEGYRFSEAGTCVADMDLRPINHCETGLHDCDIPQ RAQCKFMGHGSYTCICLPGFSGDGRACQDVNECQPSRCHPDAFCYNTPGSFVCRCKYGYQGDGFHCVPGG VEKTRCQQERERVVGTADSPRPQPPGLFVPECDEQGHYVPTQCHSSTGYCWCVDRDGQEVEGTRTGSGMR PPCLSTVAPPVHFGPPVLTAVIPPPPGTHLLFAQTGKIERLPLEGSTMTKSEAKTLLHAPDKVIIGLAFD CVDKMIYWTDISQPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSQLDRIEVAKLDGTQRR VLFETDLVNPRGIVTDSMRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCWV DAGTHRAECLNPGQPNIRKVLEGLQYPFAVTSFGKNLYYTDWKTNSVVAVDLAVSKEMDSFHPHKQTRLY GITSALSQCPEGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIEQK >XP_006258247.1 PREDICTED: nidogen-1 [Alligator mississippiensis] MGWGWGLLALLALAGPGRCGPPLLPFGSEGGDAELEAGDDVTSPALELSAPLHFYGSAVHSVHVATNGII GMNKPSKEEKYLGRFPISFGAIAPFMADLDTTSGHGKVFYREDSSPDVLQLVVSYIRRGFPEVTFDPISV VIVTWARVAPYRTPSEDAVLEDKRNTFQAVLASSDSSSYAVFLYPEDGLQFWSTHSKNAKEKIPATVGFS QASTNYLLWEKLGSYNIVAHDEESIRSLYKSSNIGKPGVWVFEIGSSSIILPAKVSSSPESLEYNDYEEY QEVTLQPSVSYHNSAETGQQHVTYDVHRKGGDQQHISYGVPQSATEEDLKSSVVTGIPPIESSLNRQADF VTGKTPPDPFQVQRFYQQEPQVIDVEEFDETGIVFRYNTDVQQTCANNRHQCSIHAVCKDYSNGFCCSCI AGYKGNGRQCVAEGSPQRVNGKVKGRIFVGNNPVPVVFENTDLHSYVVMNQGRAYTAISTIPETLGYSLL PLASVGGIIGWMFSVEQQGYKNGFSLTGGEFTRQAEVIFLGNNEKLVIKQKFNGIDEHGHLTISTEMEGR IPEISFGASVHIEPYTELYHSSTSVITSSSTREYTVTPPERDGSSSSYTAAYQWRQTISFDECIHDDSHH PVSATQQLSVDSIFVLYNKDEQILRYAMSNSIGPVSDGSADINRNPCYTNSHDCDSNAVCRPGTGNQFSC ECSVGFQGDGRFCYDVNECSEQPTVCGSNAVCNNQPGTYRCECVDGYQFSADGRSCVAIEHVINHCLAGT HNCDIPQRAQCTYVGGSSFICSCLSGFSGDGRACVDVDECQQNRCHPDAFCYNTPGSFRCQCKAGYRGDG FQCVLGEVEKTKCQHERELALGSHIPRGSRPVGDFIPQCDEYGNYKPTQCHSSSGYCWCVDSYGNEIDGT RSGPGIRPPCLSTAAPPVVIGPSVRPDSIPLPPGTHLLFAQSGKIEHVPLEGNNMKKTDAKALLYVPDKV VIGVAYDCKDKMVYWTDISGPSISQVSLHGGEPTAIIKTDLGSPEGIAIDHLGRNIFWTDSQLDRIEVAR LDGNQRRVLFDSDLVNPRAIVADAVKGNLYWTDWNRDAPKIETSYMDGTNRRILVKDDLGLPNGLTFDIY SSMLCWADAGTKKLECMNLSQPGRRKVLEGILYPFSITSYGKNLYYTDWRRDAVVAVDRTVSKENDNFQP HKRSRLYGITTALAQCPPGHSYCEVNNGGCTHLCLTTPAGRSCRCPDNTVGVDCIEQN >XP_015799438.1 PREDICTED: nidogen-1 [Nothobranchius furzeri] MSGHPRTPVTGLQRLGRREKTPPAVCSAPRPKKPLNSQRRAILGSASPCSSNSLLTPFIQKESNMGWQNQ GWLFSASLVVFWASVRSIRREEFFPFGPSAGDQLLESGDDQTFRLTLSKPVLFYDGSFDSLYINTNGFVA TKEPLNESTYLGKLPPEFGAMAPLHGDLDTSDGVGKVYFRQDNSPDVLRQAAEHINRGFPEEDEVNPINT VVITWVDIASHKPQTRGDGAERKRNTFQLVIASLETASYAIVLYARNGIQFTSTLVEDNGVVMHAGFSQG LVKGFFYSSQGNYYRTTTDDEASVRALAEETNSGLRGVWVYGIGTSPQFRNVVPGVVTDLPAETVDTQQH TDGQVKYSPAAEQIEINPLRYQPQNPEVVVVEDPEINVDVFSYNLGSCANNRNKCSQFADCRDYASGFCC HCRPGYYGNGLQCVAEGKPQRMNGKLRGKVFVENSPSPVEFNGNDLHSYVVVNDGRSYVAISDIPTSVGP SLMPLLALSNVIGWVFALEQPGFRNGFSIIGGEFTRQAEVTFQPGNEKLIIRQEFEGTDELDHLVVSTTM DGRVPAVPPGSTVQIDPYTDVYQYDSNLITSSSTRYYTVTNPDGSVETRSYQCRETITFQSCQHDESLRD VTTQMLKVDQIFVLYDVNNNLLRYAMSNKIGDVNGGQTEENPCFTGRHGCDTNAVCRPDQGSQFTCQCAS GFSGDGRRCYDIDECTENQQICGPNAICNNQPGTFRCECEDGYQFGSDGRTCIEVDRPVDHCEDGTHTCD IPDRAQCSYTGGSSYICSCLPGFVGDGRICQDIDECQPGRCHQNAVCVNTQGSFLCQCLPGYSGNGVYCS SERTKTRCEAHRDNVLSTMEAHPRGARPPISQYIPECDENGNYLPMQCHGSTGYCWCVDRNGLEISGTRS APSSRPMCIDHNTVTPTVGPWPRPDVIAPPPGTNLLFAQSGRIEHIPLEGYDMKKHDAKAVLHLPEKVII GVAYDCVEKMVYWTEITSPSISKASMLGGEPTAVIRTDLESPEGITIDHLGRTMFWTDSMRDRIEVASLD GSQRRVLIDTDLVNPRAVIADPVSGNLYWSDWNRDAPKIETSHMDGSNRRVLVKDSLTLPNGLTYDSQSS LLCWADAGTHKMECMNPSRGDRSTVLEGIRYPFGMTSFGKTIYYTDWQRDAVVSVDRYAEKETDEFQPQK RTRPYGIAAAYPQCLSGQNYCSVNNGGCTHLCLATPNGRSCKCPDNAVAVGCVESGY >XP_020764015.1 nidogen-1 [Odocoileus virginianus texanus] MLATVRRSGAAWTRALLLQLLLAGPGGCLSRQELFPFGPEHGDLELEAGDDLVSPALKLSTALHFFDRSD IDSVYVTTNGIIAMSEPPAKETHPGLFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSVTQLAAECVQR GFPEVSFKPSSVVVVTWESVAPYQGPSKDPALEGKRNTFQSILASSDSSTYAIFLYPEDGLQFYTTFSKK EENQVPAVVAFSQGLVGLIWKSDGAYNIFANDRESIGNLAKSSNSGQQGIWVFEIGSPATASGVVPADVN LGLDDGAEYDDEDYDSVTHLGLEDVVATSFPHEAPRGGDGGIYNTPSDLSPRRVATERPLTPPTERTRSF QLPGERFPQQQPQVIDVDEVEETGIVFSYNTDSRQTCTNNRHQCSVHAQCRDFATGFCCHCVAGYTGNGR QCVAEGSPQRVNGKVKGRIFVGASQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGI IGWMFAVEQDGFKNGFSITGGEFTRRAEVAFVGHPDKLIIKQQFSGIDEHGHLTISTELEGRVPQVAFGS VVHIEPYTELYHYSRQVITSSSTREYTVTEPERDGTAPSHVHTYQWRQTITFQECVHDDSRPVLPSTQQL SVDSVFVLYNQEERILRYALSNSIGPVRDGSPDALQNPCYIGSHGCDANAACRPGPGTQFTCECSIGFRG DGRTCYDIDECSEQPSVCGNHAICNNHPGTFRCECVEGYRFSEAGTCVAVMDQRPVNYCETGLHDCDISQ RAQCIYTGGSSYTCSCLPGFSGDGRACKDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFHCVPGE VEKTRCQREREHILGAVDSQRPRPPGLFVPECDDHGHYAPMQCHGSTGYCWCVDRDGREVQGTRTRPGMR PPCLSTVAPPVHHGPPVPTAVIPLPPGTHLLFAQTGKIEHLPLEGSTMTKSEAKTLLHTPDKVIIGLAFD CVDKMVYWTDISQPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSHLDRIEVAKLDGTQRR VLFETDLVNPRGIAADSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCWV DAGTHRAECLKPGQPNRRTVLEGLQYPFGVTSFGKNLYYTDWKTNSVAAVDLAISKETDSFHPHKQTRLY GITSALSQCPEGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIEQK >XP_030297897.1 nidogen-1 [Sparus aurata] MGWQERGWLVCASFLGFVASVESITRGELFPFGPSARDRLMEAGNDQTHRLQLDNPVLFYDGSFDSIFIN TNGFVATAEPTSESTYLGKMPPGFGMIAALQGDLDTRDGEGRVYFRQDSSRDALRRSAEIINRAFPEDDE FNPTHAVVITWVDVTAHEPHSRGDGNRKRNTFQLVIASMETASYAIVLYPRDGIQFTSTPANGQSVVMHG GFSKGLVKGFLFSSQGPYYRTTTEDEASIRALAEETNSGQRGVWVYEIGTSPYFTNVVAGEVTDLPAEAT RRPAYTDGQQVEYPHFESEGAQIEVHPVQYQPHQPGNPEVVVVDDTDINVDVFSYNLGTCANNANKCSQF ADCKDYSSGYCCHCRPGFYGNGIQCVAEGKPQRMNGKVYGKVYVGNSPSPVEFTSNDLHSYVVVNDGRSY VAISEVPYTLGPSLQPLSALGGVIGWAFALEQPGFKNGFSIIGGEFTRQAEVTFLPGNEKLTIRQEFKGI DEHDHLAVSTTLEGRVPEVPRGSTVQIERYSEIYQYSNNLITSSSTRDYVVSLPDGSTETRMYQWRQTIT FQSCQHGDSLRDMKPTQMLSVDQVFVMYDANNELIRFAMSNKIGDVNGGQPQENPCFTGRHGCDTNAVCR PGEGTQFNCECAAGFNGDGRTCYDIDECAENPQICGFHAICNNQPGTFRCECEDGYQFGNDGHTCTEIDR VVDACEEGTHDCDIPERAQCSYTGGSSFICSCLPGFFGDGRVCKDIDECQPGRCHQDAVCYNTQGSFTCQ CRSGYYGDGFYCSAERTKTQCETHRDSLLGAGPRGPRPPIGQYVPTCDENGAYEPMQCHSSTGHCWCVDR NGQEIPGTRSGPGSRPMCINHGGVPPPVGPTPRPDVHPLPPGTHLLFAQSGRIEHVPLEGHDMKKEDAKA VLHLPEKVIIGVAYDCVEKMVYWTEITSPSISKASIQGGEPTEVIRSDLDSPEGIAVDHLGRTLFWTDSV KDRIEVASLDGSQRRVIIDSDLVNPRAIITDPPNGNLYWTDWNRDAPKIETSYMDGSNRRVLVKDDLGLP NGLTYDPQSSMLCWADAGTHKMECTHPARGDRRQVMEGIQYPFGITSFGKNIYYTDWRRDAVVAVDRYAG KESDQFQPQKRTKLYGITTAYAQCPSGQNYCAVNNGGCTHLCLATPAGRSCKCPNNAVGVGCVERDGGY
Mafft alignment of selected proteins >sp|P14543|NID1_HUMAN Nidogen-1 OS=Homo sapiens OX=9606 GN=NID1 PE=1 SV=3 ------------------------------------------------------------ ----MLASSSRIRAAWTRALL------------------LPLLLAGPV------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPG---------QGD--LELEDGDDFVSPALE LSG-----------ALRFYDRSDIDAV--------------------------------- ---------------------------YVTTNGIIATSE--------PPAKESHPGL-FP PTFGAVAPFLADLDTT----------------DGLGKVYYR-EDLSPSITQ------RAA ECVHRGFPEI-------------------------------------------------- -SFQPSSAV-------------------------------VVTWESVA-PYQGPSRDPDQ KG--KRNTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKKE---------NNQVPAVVAF SQGSVG-FLWKSNGA-YNIFANDRESVENLAKS-----------------SNSGQQGVWV FEIGSP----------ATTNGVVPADVI--------LGT--------------------- -EDGAEYD---DEDED-----------YDLATTRLGLEDVGTTPF-----SYKALRRGGA D---TYSVPSVLS-----------------PRRA-ATER---PLGPPTERTR-------S FQLAVETFHQQ-----HPQVIDV----------D-EVEETGV-VFSYNTDSR----QTCA N-NRHQCSVH-AECRDYATGFCCSCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGSS Q-VPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APVGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGHPGNLVI--- -------------KQRFSGIDEH------GHLTIDTELEGRVPQIPFGSSVHIEPYTELY -HYSTSVITSSS----TREYTVTEPERDGASPSRIYTYQWRQTITFQE---C-------- -VHDDSRPA---LPSTQQLSVDSVFVLYNQEEKILRYALSN------SIGPVREGS---- ---------------------------PDALQ-NPCYIGTHGCD-TNAACRPG------- ---------------------------------PRTQFTCECSIGFRG-------DG--- ----RTCY---------------------------------------------------- ------------------------DIDECSEQPSVCG--SHTICN-------NHPGTFRC ECVEGYQFS-DEG-TCVAVV---DQRPINY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHNCDIPQRAQCIYTGGS-SYTCSC-------LPGF SGDG-QACQD----------VDE----------------C--QPSRCHPDAFCYNTP--G SFTCQCKP------GYQGDGFRCV------------------------------------ --------------------------------------------PG--EVEKTRCQHERE HILGAA---------GATDPQRPI---------------------------PPGLF---- -----VPE-----------------------------------CDAHGH---YAPTQCHG ST--------GYCWCVDRDGREVEGTR------------TRPGMTPPCLSTVA-PPIH-- ------------------------------------------------------------ -------------------------------QGPAVPTAVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIERLPLEGNTMRKTE AKAFLHVPA-KVIIGLAFDCVDKMVYWTDITEPSIGRASLH-GGEPTTII-RQDLGSPEG IAVDHLGRNIFWTDSNLDRIEVAKLDG-TQRRVLFETDLVNPRGIVTDSVRGNLYWTDWN RDNPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDAFSSQLCWVDAGTNRAECLNPSQ--P SRRKALEGLQ----YPFAVT-SYGKNLYFTDWKMNSV-VALDLAIS-KETDAFQPH-KQT RLYGITTALSQCPQG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------EQK------------ ----------------------------- >tr|F1RAG3|F1RAG3_DANRE Nidogen 1a OS=Danio rerio OX=7955 GN=nid1a PE=1 SV=2 ------------------------------------------------------------ ----MGRHG-------HRHPFWV----------------ILFGLTLSV------------ ------------------------------------------------------------ -------------SGITR----HELFPFGRN---------AGD--QSLREGNDE-TQEVN LDK-----------PITFHDEQ-FSKI--------------------------------- ---------------------------YINTNGFVALEK--------PTGESEYLEN-MP ASFKMIAALQGDLDTS----------------DGVGKVFFR-QDFSTALLQ------QAA DHINRAFPED-------------------------------------------------- DLVNPIHAL-------------------------------VVTWLDVA-SHKAESRGDGL EHSIRRNTFQLVIASVETSSYAILLYPRDSIQFQST--------------GSGYTVHAGF SK---------TQELYYRNTEDTEASVKDLPEQ-----------------TNSGKRGVWV YEIGTF----------PHFTNIAPGEVP-------------------------------- -----------DLPLD--------------SLRRSETQNQQQQVY-----PDV-QQENLD G---VYHHPEH-------------------PPPI-------------------------- -QVHTVQFTPQ-----DPQVVEI----------ENDDNIQVD-VFTYNSG-------QCG G---QKCSKF-AEC----SGRCCVCKPGYY--GSGVHCVPEGVPQRMNGKVSGRVFVGNS P-VPVDFASNDL-----------HSYVVANDGRAYVAIS-AIPPVI-------GFSLQPL ------SSVGGVIGW----AFALQQP-GFKNGFSIIGGEFKRQADVSFQPGGEKLTI--- -------------SQEFRGIDEH------DHLMVDTRLEGKIPEVPQGATVQIDSYSEIY -QYSINLITSSS----TREYVISLPD----GSTQSRSYNFRETITFQG---C-------- -QFDE-------VPSTQMLSVEQVFVMYDMGAQLLRYAMSN------KIGDVNGGQ---- ---------------------------SE--E-NACFTGRHGCD-TNAVCKPG------- ---------------------------------QGNQFTCECAAGFTG-------DG--- ----RACY---------------------------------------------------- ------------------------DIDECRETPQICG--QNSICN-------NQPGTFRC ECLDGFQFA-SDGQTCVEV-----HRPVDP------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CRSG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------THDCDVPERARCSYTGGS-SYICTC-------APGF MGDG-RRCQD----------IDE----------------C--QVNQCHENAVCFNTP--G SFSCQCNP------GFHGDGFYC------------------------------------- --------------------------------------------ST--EREKTRCELHKE SVVG-----------FGPHSARP----------------------------QPGRF---- -----VPT-----------------------------------CDAQGR---YEPMQCHA SI--------GQCWCVDRDGEEISGTR------------TGPGRFPVCRGHDE-SGP--- ------------------------------------------------------------ -------------------------------IRPTPNPNISPLPPG-------------- ------------------------------------------------------------ -----------------------------------SHILFTQSGKIEYIPLDGHNLKKNE AKTALHLPE-KVVIGIAYDCVEKMIYWTDISTPAISRANLQ-GGEPVQLI-KSDIGSPEG IAIDHLGRNMFWTDSMKDRIEVSSLDG-TQRRVLVNTDLVNPRAILTDSTNGYIYWADWN RESPKIEMAYMDGTNRRVLAK-DDLSLPNGLTYDPQTSLLCWADAGTHKVECMNPQQ--G RRTQLMEEIQ----YPFGLT-TDGKNFYYTDWTRVSV-VVVDRHLR-REVDEFQPQ-KRT RLYGITTAHARCPAG--QNYCSSNNGGCT--HLCLAT---PAG-RSCRCPDNAAE----- -LGCV------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERE------------ ----------------------------- >NP_035047.2 nidogen-1 precursor [Mus musculus] ------------------------------------------------------------ ----MLDASGCSWAMWTWALL------------------QLLLLVGPG------------ ------------------------------------------------------------ -------------GCLNR----QELFPFGPG---------QGD--LELEAGDDVVSPSLE LIG-----------ELSFYDRTDITSV--------------------------------- ---------------------------YVTTNGIIAMSE--------PPATEYHPGT-FP PSFGSVAPFLADLDTT----------------DGLGNVYYR-EDLSPFIIQ------MAA EYVQRGFPEV-------------------------------------------------- -SFQPTSVV-------------------------------VVTWESVA-PYGGPSSSPAE EG--KRNTFQAVLASSNSSSYAIFLYPEDGLQFFTTFSKKD---------ESQVPAVVGF SKGLVG-FLWKSNGA-YNIFANDRESIENLAKS-----------------SNAGHQGVWV FEIGSP----------ATAKGVVSADVN--------LDLD-------------------- -DDGADYE---DEDYD-------------LVTSHLGLEDVAT-PS-----PSHSPRRGYP D---PHNVPRILS-----------------PGYE-ATER---PRGVPTERTR-------S FQLPAERFPQH-----HPQVIDV----------D-EVEETGV-VFSYNTGSQ----QTCA N-NRHQCSVH-AECRDYATGFCCRCVANYT--GNGRQCVAEGSPQRVNGKVKGRIFVGSS Q-VPVVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APIGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFLGHPGKLVL--- -------------KQQFSGIDEH------GHLTISTELEGRVPQIPYGASVHIEPYTELY -HYSSSVITSSS----TREYTVMEPDQDGAAPSHTHIYQWRQTITFQE---C-------- -AHDDARPA---LPSTQQLSVDSVFVLYNKEERILRYALSN------SIGPVRDGS---- ---------------------------PDALQ-NPCYIGTHGCD-SNAACRPG------- ---------------------------------PGTQFTCECSIGFRG-------DG--- ----QTCY---------------------------------------------------- ------------------------DIDECSEQPSRCG--NHAVCN-------NLPGTFRC ECVEGYHFS-DRG-TCVAAE---DQRPINY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHNCDIPQRAQCIYMGGS-SYTCSC-------LPGF SGDG-RACRD----------VDE----------------C--QHSRCHPDAFCYNTP--G SFTCQCKP------GYQGDGFRCM------------------------------------ --------------------------------------------PG--EVSKTRCQLERE HILGAA---------GGADAQRPT---------------------------LQGMF---- -----VPQ-----------------------------------CDEYGH---YVPTQCHH ST--------GYCWCVDRDGRELEGSR------------TPPGMRPPCLSTVA-PPIH-- ------------------------------------------------------------ -------------------------------QGPVVPTAVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIERLPLERNTMKKTE AKAFLHIPA-KVIIGLAFDCVDKVVYWTDISEPSIGRASLH-GGEPTTII-RQDLGSPEG IALDHLGRTIFWTDSQLDRIEVAKMDG-TQRRVLFDTGLVNPRGIVTDPVRGNLYWTDWN RDNPKIETSHMDGTNRRILAQ-DNLGLPNGLTFDAFSSQLCWVDAGTHRAECLNPAQ--P GRRKVLEGLQ----YPFAVT-SYGKNLYYTDWKTNSV-IAMDLAIS-KEMDTFHPH-KQT RLYGITIALSQCPQG--HNYCSVNNGGCT--HLCLPT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERK------------ ----------------------------- >XP_043332969.1 nidogen-1 isoform X1 [Cervus canadensis] ------------------------------------------------------------ ----MLATVRRSGAAWTRALL------------------LQLLLAGPG------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPE---------HGD--LELEAGDDLVSPALE LST-----------ALHFFDRSDIDSV--------------------------------- ---------------------------YVTTNGIIAMSE--------PPAKETHPGP-FP PTFGAVAPFLADLDTT----------------DGLGKVYYR-EDLSPSVTQ------LAA ECVQRGFPEV-------------------------------------------------- -SFKPSSAV-------------------------------VVTWESVA-PYQGPSKDPAL EG--KRNTFQSILASSDSSTYAIFLYPEDGLQFYTTFSKKE---------ENQVPAVVAF SQGLVG-LIWKSDGA-YNIFANDRESIGNLAKS-----------------SNSGQQGIWV FEIGSP----------ATASGVVPADVN--------LGL--------------------- -DDGAEYD---DEDYD--------------SVTRLGLEDVVTTSF-----PYEAPRRGDS G---TYNTPSDLS-----------------PRRM-ATER---PLTPPTERTR-------S FQLPGERFPQQ-----QPQVIDV----------D-EVEETGI-VFSYNTDSR----QTCA T-NRHQCSVH-AQCRDFATGFCCRCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGAS Q-VPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APIGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGHPDKLIV--- -------------KQQFSGIDEH------GHLTIDTELEGRVPQIAFGSTVHIEPYMELY -HYSRRVITSSS----TREYTVTEPERDGTSPSHVHTYQWRQTITFQE---C-------- -VHDDSGPV---LPSTQQLSVDSVFVLYNQEERILRYALSN------SIGPVRDGS---- ---------------------------PDALQ-NPCYIGSHGCD-ANAACRPG------- ---------------------------------PGTRFSCECSVGFRG-------DG--- ----RACY---------------------------------------------------- ------------------------DIDECSEQPSVCG--NHAICN-------NHPGTFRC ECVEGYRFS-EAG-TCVAVM---DQRPVNY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHDCDIPQRAQCIYTGGS-SYTCSC-------LPGF SGDG-RACKD----------VDE----------------C--QPSRCHPDAFCYNTP--G SFTCQCKP------GYQGDGFHCV------------------------------------ --------------------------------------------PG--EVEKTRCQLERE HIL------------GAVDSQRPR---------------------------PPGLF---- -----VPE-----------------------------------CDEHGH---YAPVQCHG ST--------GYCWCVDRDGREVQGTR------------TRPGMRPPCLSTVA-PPVH-- ------------------------------------------------------------ -------------------------------HGPPVPTAVIPVPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIEHLPLEGSTMTKSE AKALLHAPD-KVIIGLAFDCVDKMVYWTDISQPSIGRASLH-GGEPTTII-RQDLGSPEG IALDHLGRNIFWTDSHLDRIEVAKLDG-TQRRVLFETDLVNPRGIATDSVRGNLYWADWN RDNPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDAYSSQLCWVDAGTHRAECLKPGQ--P NRRTVLEGLQ----YPFGVT-SFGKNLYYTDWKTNSV-VAVDLAIS-KETDSFHPH-KQT RLYGITSALSQCPEG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------EQK------------ ----------------------------- >KAF4018772.1 hypothetical protein G4228_010616 [Cervus hanglu yarkandensis] ------------------------------------------------------------ ----MLATVRRSGAAWTRALL------------------LQLLLAGPG------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPE---------HGD--LELEAGDDLVSPALE LST-----------ALHFFDRSDIDSV--------------------------------- ---------------------------YVTTNGIIAMSE--------PPAKETHPGP-FP PTFGAVAPFLADLDTT----------------DGLGKIYYR-EDLSPSVTQ------LAA ECVQRGFPEV-------------------------------------------------- -SFKPSSAV-------------------------------VVTWESVA-PYQGPSKDPAL EG--KRNTFQSILASSDSSTYAIFLYPEDGLQFYTTFSKKE---------ENQVPAVVAF SQGLVG-LIWKSDGA-YNIFANDRESIGNLAKS-----------------SNSGQQGIWV FEIGSP----------ATASGVVPADVN--------LGL--------------------- -DDGAEYD---DEDYD--------------SVTRLGLEDVVTTSF-----PYEAPRRGDS G---TYNTPSDLS-----------------PRRM-ATER---PLTPPTERTR-------S FQLPGERFPQQ-----QPQVIDV----------D-EVEETGIAVFSYNTDSR----QTCA T-NRHQCSVH-AQCRDFATGFCCRCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGAS Q-VPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APIGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGHPDKLIV--- -------------KQQFSGIDEH------GHLTIDTELEGRVPQIAFGSTVHIEPYTELY -HYSRRVITSSS----TREYTVTEPERDGTAPSHVHTYQWRQTITFQE---C-------- -VHDDSGPV---LPSTQQLSVDSVFVLYNQEERILRYALSN------SIGPVRDGS---- ---------------------------PDALQ-NPCYIGSHGCD-ANAACRPG------- ---------------------------------PGTRFSCECSVGFRG-------DG--- ----RACY---------------------------------------------------- ------------------------DIDECSEQPSVCG--NHAICN-------NHPGTFRC ECVEGYRFS-EAG-TCVAVM---DQRPVNY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHDCDIPQRAQCIYTGGS-SYTCSC-------LPGF SGDG-RACKD----------VDE----------------C--QPSRCHPDAFCYNTP--G SFTCQCKP------GYQGDGFHCV------------------------------------ --------------------------------------------PG--EVEKTRCQLERE HIL------------GAVDSQRPR---------------------------PPGLF---- -----VPE-----------------------------------CDEHGH---YAPVQCHG ST--------GYCWCVDRDGREVQGTR------------TRPGMRPPCLSTVA-PPVH-- ------------------------------------------------------------ -------------------------------HGPPVPTAVIPVPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIEHLPLEGSTMTKSE AKALLHAPD-KVIIGLAFDCVDKMVYWTDISQPSIGRASLH-GGEPTTII-RQDLGSPEG IALDHLGRNIFWTDSHLDRIEVAKLDG-TQRRVLFETDLVNPRGIATDSVRGNLYWADWN RDNPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDAYSSQLCWVDAGTHRAECLKPGQ--P NRHTVLEGLQ----YPFGVT-SFGKNLYYTDWKTNSV-VAVDLAIS-KETDSFHPH-KQT RLYGITSALSQCPEG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------EQK------------ ----------------------------- >XP_018118629.1 nidogen-1 isoform X1 [Xenopus laevis] ------------------------------------------------------------ ----MLYFKQ--KGLFFGGLLHV----------------LFCLLPNPG------------ ------------------------------------------------------------ -------------SFIKV----DTFFPYGRD---------VGD--LLLTPGDDSDSEPLR PNQ-----------SLHFYDGT-ISTL--------------------------------- ---------------------------FVTTNGMIATSK--------PPPEDDYLEQ-FP PDFGLIAPFLSDIDTS----------------EG-GNVFYR-EDTSQDVLH------LAS KHINRGFPGS-------------------------------------------------- -TFIPKSAL-------------------------------VFTWEDVL-PYYSQRGDAIP HN--KGNTFQAVLASDESKSYAIFLYPEDGLNFHGTQPKNNY--------NEENSARVGF SKGAEAFILWKTKGP-HNEFANDYYSLEMLRWK-----------------TNSGMQGVWI YEIGGP----------STLKSVVAANVEH------FATL--------------------- -DEKEENH---SEETE-------------------------------DFNDHYVTEQDYE NNPLKPNIPGLNL-------------IPVDPYLD--------QEDVILGNV--------- -NFQVPSFPQN-----NPQIVIVD---------D-ELEDTGV-VFQYNTGNQ----QTCA N-NRHQCSSQ-AFCKDYSTGFCCTCIPGYY--GNGRQCVAEGSPQRVNGKVKGKIYVGSN P-IPVVFEGIDL-----------HSYVVVNDGRAYTAIS-TIADSL-------GYSLLPL ------ASIGGVIGW----MFSVQQP-GYKNGFSITGGEFTRKTEVTFLHSNKKLVI--- -------------LQKFSGIDEH------GHLTISTELDGSVPEIPYGSTVHIEPYTELY -QTSSSVITSSS----NREYTVEFPQ----DGSETFTYQWKQTITFTE---C-------- -VHDTAAPT---VPAIQQLSVDRVFVLYNREEKILRYASSN------SIGPITDSP---- ---------------------------VDTNR-NPCYIGAHNCD-TNAVCRPA------- ---------------------------------QGNQYICECTSGFRG-------DG--- ----RTCY---------------------------------------------------- ------------------------EIDECQEQQDICG--DNAICN-------NQPGTFRC ECNDGYQFL-EDGRTCASV-----ERTINH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CLTG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------THNCDIAERAHCIYTGGS-SYICAC-------LSGY SGDG-RVCED----------VDE----------------C--ETSQCHPDAVCYNIP--G SFSCHCKP------GYQGNGFQCF------------------------------------ --------------------------------------------PG--EPQKTPCQLHQD SILGS----------PSVRGARP-----------------------------VGQF---- -----LPQ-----------------------------------CDESGN---YVPRQCHS GS--------GYCWCVDKDGNELPGTR------------TRPGLSPPCLDIVTHPPPT-- ------------------------------------------------------------ -------------------------------VGPVVRPDVAPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFVQSGKIEHVPLEGNSMKKSD AKTLLHIPD-KVIIGVSYDCVDKTVYWTDITGPSISRASIN-GGEPTAII-KTELGSPEG IAVDHLGRNIFWTDSVLNTIEVAKLDG-SNRRILFDTDLENPRGIVADALKGNLYWTDWN RVAPKIETSYMDGTNRRILVK-DDLGLPNGLTIDAYSSMLCWVDAGTKRMECMNPSQ--P ARRKIVEGIQ----YPFGIT-SYGKNIFYTDWKRDSI-VAIDRTIS-KENDNFQPP-KRS RLYGITTAYSQCPQG--QNYCAVNNGGCK--HLCLAT---PGG-RSCLCPENSTG----- -VDCL------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------DRN------------ ----------------------------- >XP_040188888.1 nidogen-2 [Rana temporaria] ------------------------------------------------------------ ----MVSRV-------LRILH------------------WHCLLLGFS------------ ------------------------------------------------------------ -------------AAISR----QELFPYGES---------RGD--RLLPDGDDETSEVVT LTQ-----------PILFYEAD-FKEL--------------------------------- ---------------------------YVGTNGIISTQD--------FPRETQYVDDGFP TDFPVIAPFLSDIDTS----------------NGKGKIYYR-QDNSPDILS------TVA RQVDRGFPQA-------------------------------------------------- -AFSPTNVF-------------------------------MVTWDNVG-AYEEVTRHAEP SN--KLNTFQAVLAYDDSDTYAIFLYPEHGLQFFGTRPKESY------NVHLDLPARVGF SRGDSE--MLKKEAPFYS-VTSSEQSVKNLYQT-----------------SNVGVPGVWV FHIGSL----------SEIDNVIPAKVPHHHPQQRFVPLINSHNDFPEQQQQQQLENQFN GENNYEDNYE-DEDYPA-----G-------QTTEAPTTDSAVLN------PDRTHDFIDA EDHATLYTPNNPLPPSQEEPSWT-PYNPDEPLVEPEIQR---SESRVLGNIPSYETQEEP SESVSEDFNNVTPNPVDPQRSDVYRSN-RFYGNEEVGGLDTD-VLTFNPVSR----ETCD R-KPGYCSPY-AFCTDYATGFCCHCQDSYY--GNGVHCLPKGAPHRVNGKVSGNLLVGQR ---PVTFDGIDM-----------HAYIVVNDGRAYTAIS-QVPEPA-------SWSLTPL ------TAIGGLFGW----LFALEKP-GHQNGFSITGAKFVHNLEAVFSPGEEVIHV--- -------------TQTADGFDSD------NYIHVRTTIKGKIPYIPETSTVQIAPYYEIY -QHSGSVVTSTA----YREYTVTSQS----GDVQKFSYRLKQNITYQE---C-------- -GHAQKYP-----PTAQKLSVDRVFAMHNKDEKVLRFAITS------HIGSLHDSS---- ---------------------------QEPTQGNPCFDGTHQCD-TRAQCQPA------- ---------------------------------TGLNYSCVCASGYRG-------DG--- ----RDCT---------------------------------------------------- ------------------------DYDECEDQLDNCG--QNTRCV-------NLPGSFRC ECVPGYVFS-ADGQNCILG-----SSFGNP------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CEDG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------THSCDLT-TSQCVPRGDG-VFTCEC-------FPGY TRSG-QSCID----------VDE----------------C--AERRCHPDATCANVP--G SFSCRCNP------GFTGDGFQCTQAPEEPRPSTPCLEKRHAAQPRGPRPPLIGAFLPEC DEEGNYVPLQCHGSTGHCWCVDRNGNEIEGTRRPAGSGRPQCGIPEPTQRPQTMCERWKQ SLVDHY-------------GGSP----------------------------SAEHY---- -----IPQ-----------------------------------CDAYGE---FSPLQCHG NS--------GYCWCVDKDGREIEGSR------------TQPGMTPACLPSVA-PPT--- ------------------------------------------------------------ -------------------------------VRPTPRPDVTPPTSG-------------- ------------------------------------------------------------ -----------------------------------TYLLYAQGQQIGYLPLDGVKFRKDK ARTLLALHG-SIVVGIDYDCQEKKVYWTDVSGRTISRAGLEPGAEPEVLI-STDLMSPEG LAIDYLRKTMFWTDSGTDKIESARLDG-TFRKTLFDTNLVNPRAITVDAVRGNLYWTDWN REAPKIETSYVDGSNRRILVN-DNIGLPNGLTFDPFSKQICWADAGTKKLECILSDG--S GRRVIQSNLN----YPFSVV-GFANHFYHTDWRRDGV-ISINKENG-QITEEYLPE-QRS HLYGITAIYPYCPSG--KK----------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------- >OWK09497.1 NID2 [Cervus elaphus hippelaphus] ------------------------------------------------------------ ----M------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GATRV---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------PPQLVAIRR----------------------------------- ------------------------------------------------------------ ----------------------------------------QV------------------ --------------W--------------------------------------------- ---------------------------------------------PTPASVHL------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------DVDECATGFHRCG--PNSVCV-------NLLGSYRC ECRSGYEFA-DDRHTCILI-----TPPPDP------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CEDG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------RHNCAPASQARCIHHGDG-SFSCAC-------LPGY AGDG-HRCTD----------VDE----------------C--SENRCHPSATCSNTP--G SFSCRCQP------GYYGDGFQCT------------------------------------ --------------------------------------------PEPTQRPRTVCERWRE SLLEHY-------------GGTP----------------------------RDDQY---- -----VPQ-----------------------------------CEGLGH---FTPLQCHG KS--------DFCWCVDQDGREVQGTR------------SQPGITPACIPTVA-PPT--- ------------------------------------------------------------ -------------------------------IRPTPRPDVTPPPVG-------------- ------------------------------------------------------------ -----------------------------------TFLLYAQGQQIGHLPLNGTRLQKDM AKTLLSLHG-SIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPETVI-NSGLISPEG LAIDHFRRTMYWTDSGLDKIERARLDG-SERRALFHTDLVNPRAIAVDPIQGNLYWTDWN REAPKIEMSSLDGENRRILVN-KDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDG--T GRRVIQNNLN----YPFNIV-SYADHFYHTDWRRDGV-IAVNRDTS-QFTDEYLPE-QRS HLYGITAVYPYCPGK--QLLRQ---------RLGISRV--EEH-RSSS------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------- >XP_213954.4 nidogen-1 [Rattus norvegicus] ------------------------------------------------------------ ----MLDASGWSWEMWTWALL------------------QLLLLAGPA------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPG---------QGD--LELEAGDDVVSPSLE LIG-----------ELSFYDRSDITSV--------------------------------- ---------------------------YVTTNGIIAMSE--------PPATEFHPGT-FP PSFGSVAPFLADLDTT----------------DGLGNVYYR-EDLSPFIIQ------MAA EYVQRGFPEV-------------------------------------------------- -SFQPTSVV-------------------------------VVTWESMA-PYGGPSGSLVE EG--KRNTFQAVLASSNSSSYAIFLYPDDGLQFFTTFSKKD---------ENQVPAVVGF SKGLEG-FLWKSNGA-YNIFANDRESIENLAKS-----------------SNAGHQGVWV FEIGSP----------ATAKGVVPADVN--------LDVD-------------------- -DDGADYE---DEDYD-------------LQTSHLGLEDVATQPF-----PSHSPRRGYP D---PHNVPRTLA-----------------PSYE-ATER---PHGIPTERTK-------S FQLPVERFPQK-----HPQVIDV----------D-EVEETGV-VFSYNTGSQ----QTCA N-NRHQCSVH-AECRDYATGFCCRCVANYT--GNGRQCVAEGSPQRVNGKVKGRIFVGNS Q-VPVVFENTDL-----------HSYVVMNHGRSYTAIS-TIPESV-------GYSLLPL ------APIGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFLGHPGKLIL--- -------------KQQFSGIDEH------GHLTINTELEGRVPQIPYGASVHIEPYTELY -HYSSSVITSSS----TREYTVTEPDQDSAVPSHTHVYQWRQTITFQE---C-------- -AHDDSRPA---LPSTQQLSVDSVFVLYNKEERILRYALSN------SIGPVRDGS---- ---------------------------PDALQ-NPCYIGTHGCD-SNAACRPG------- ---------------------------------PGTQFTCECSVGFRG-------DG--- ----KACY---------------------------------------------------- ------------------------DIDECSEQPSRCG--NHAICN-------NHPGTFRC ECMEGYHFS-DRG-ICVAAV---DQRPINY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHNCDIPQRAQCIYMGGS-SYTCSC-------LPGF SGDG-RACQD----------VDE----------------C--QHSRCHPDAFCYNTP--G SFRCQCKP------GYQGDGFRCV------------------------------------ --------------------------------------------PG--EVGKTRCQLERE HILGAA---------GATDAQRPT---------------------------LQGMF---- -----VPQ-----------------------------------CDEYGH---YTPTQCHH ST--------GYCWCVDRDGQELEDTR------------TPPGMRPPCLSTVA-PPIH-- ------------------------------------------------------------ -------------------------------QGPVVPTAVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIERLPLERNTMKKTE AKAFLHIPA-KVIIGLAFDCVDKVVYWTDISEPSIGRASLH-GGEPTTII-RQDLGSPEG IALDHLGRTIFWTDSHLDRIEVAKMDG-TQRRVLFDTGLVNPRGIVTDSVRGNLYWTDWN RDNPKIETSHMDGTNRRILAQ-DNLGLPNGLTFDAFSSQLCWVDAGTHRAECLNPAQ--P SRRKVLEGLQ----YPFAVT-SYGKNLYYTDWKTNSV-IAMDLAVS-KEMDAFHPH-KHT RLYGITIALSQCPQG--HNYCSVNNGGCT--HLCLPT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERK------------ ----------------------------- >XP_040524442.1 nidogen-1 isoform X1 [Gallus gallus] ------------------------------------------------------------ ----MGV--------GTRCAPC-----------------ALLALALPL------------ ------------------------------------------------------------ --------------ALPA----ELLLPHGAE---------RGD--AALEPGDDARSAALE LGT-----------ALHFYGAA-VRSL--------------------------------- ---------------------------YVATNGIIAVNE--------PKNEEKYLGQ-FP VSFGAIAPFMADLDTT----------------DGRGNVYYR-EDSSSDVLQ------LAS DYIKGGFPEA-------------------------------------------------- -AFDPSSAV-------------------------------IVTWKLVA-PYQGPGEDLTL EE--KRNTFQAVLASSDSSSYAIFLYPEDGLQFYSAYSKND---------DGKIPAMVGF SQASTNYYFWENPGS-YNVIANDEDSIRNLHKS-----------------SNAGRQGVWV FEIGSS------------SDTIVPAKVS--------SVL--------------------- --ASLEPS---EEDQE--------------LTSKPFMSDYGSTEIRPQYVTSSTDSIEED Q-HVTYSVPQLAV----EDFITSYQDVTGTPSTE-SFYR---HREFPTAKAP-------P RQFPAQQFPPQ-----GPQVIDV----------E-EFDETGI-VFRYHTDVQ----QTCA N-NRHQCSVH-AICKDYPNGFCCSCIAGYK--GNGRQCVAEGSPQRVNGKVKGRVFVGNN P-VPVTFENTDL-----------HSYVVMNHGRAYTAIS-TIPEAL-------GYSLLPL ------ASIGGVIGW----MFAVEQQ-GYKNGFSITGGEFTRQTEVTFLGNNEKLVI--- -------------KQKFSGIDEH------GHLTISTEMEGRVPEVPSGASVHIEPYTELY -HASSSVITSSS----TREYTVTEPERDGVASTYTGAYQWRQTISFDE---C-------- -IHDDSLHA---ASATQQLSVDSIFVLYNRDEQILRYAMSN------SIGPISDGS---- ---------------------------ADISR-NPCYTGTHNCD-TNAVCRAG------- ---------------------------------TGNRFSCECSIGFRG-------DG--- ----NVCY---------------------------------------------------- ------------------------DIDECSEQPGLCG--SNAVCN-------NQPGTYRC ECVDGYQFA-ADGRTCVAV-----EYAINH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CQTG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------THGCDIPQRAQCVYTGGS-AYICTC-------LPGF SGDG-RACED----------IDE----------------C--QQGHCHPDAFCYNTP--G SFSCQCKA------GYRGDGFQCV------------------------------------ --------------------------------------------LG--GVVKTKCQHEKE VALGS----------GGTFFQREI---------------------------RVGQF---- -----IPQ-----------------------------------CDEHGN---YVPTQCHG ST--------GYCWCVDRDGNEIDGTR------------SGPGVRPPCLSTAA-PPVG-- ------------------------------------------------------------ -------------------------------IGPSVRPDTIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQSGKIEHVPLEGNNMKKNG AKALLHIPD-KVIIGVAYDCMDKMVYWTDISGPSISRASLH-GGEPTTII-RTDLGSPEG IALDHLGRNIFWTDSQLDRIEVARLDG-RQRRILFDTGLVNPRAIVVDPVRGNLYWTDWN REAPKIETSYMDGTNRRILVK-DDLGLPNGLTFDPYSSMLCWVDAGTKRLECMNPNQ--L GRRKIVEGIQ----YPFGVT-SYGKNLYYTDWRRDAV-VAVDRMIS-VENDNFQPH-KRS RLYGITTAFAQCPGG--HNYCTVNNGGCT--HLCLAT---PEG-RSCRCPDNTVG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERN------------ ----------------------------- >XP_001156001.1 nidogen-1 [Pan troglodytes] ------------------------------------------------------------ ----MLASSSRIRAAWTRALL------------------LPLLLAGPV------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPG---------QGD--LELEDGDDLVSPALE LSG-----------ALRFYDRSDIDSV--------------------------------- ---------------------------YVTTNGIIATSE--------PPAKESHPGL-FP PTFGAVAPFLADLDTT----------------DGLGKVYYR-EDLSPSITQ------RAA ECVHRGFPEI-------------------------------------------------- -SFQPSSAV-------------------------------VVTWESVA-PYQGPSRDPDQ KG--KRNTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKKE---------NNQVPAVVAF SQGSVG-FLWKSNGA-YNIFANDRESIENLAKS-----------------SNSGQQGVWV FEIGSP----------VTTNGVVPADVI--------LGT--------------------- -EDGAEYD---DEDED-----------YDLATTRLGLEDVGTTPF-----SYKALRRGGA D---TYSVPSVLS-----------------PRRA-ATER---PLGPPTERTR-------S FQLAVETFHQQ-----QPQVIDV----------D-EVEETGV-VFSYNTDSR----QTCA N-NRHQCSVH-AECRDYATGFCCSCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGSS Q-VPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APVGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGHPGNLVI--- -------------KQRFSGIDEH------GHLTIDTELEGRVPQIPFGSSVHIEPYTELY -HYSTSVITSSS----TREYTVTEPERDGASPSRIYTYQWRQTITFQE---C-------- -VHDDSRPA---LPSTQQLSVDSVFVLYNQEEKILRYALSN------SIGPVREGS---- ---------------------------PDALQ-NPCYLGTHGCD-TNAACRPG------- ---------------------------------PRTQFTCECSIGFRG-------DG--- ----RTCY---------------------------------------------------- ------------------------DIDECSEQPSVCG--SHTICN-------NHPGTFRC ECVEGYQFS-DEG-TCVAVV---DQRPINY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHNCDIPQRARCIYTGGS-SYTCSC-------LPGF SGDG-QACQD----------VDE----------------C--QPSRCHPDAFCYNTP--G SFTCQCKP------GYQGDGFRCV------------------------------------ --------------------------------------------PG--EVEKTRCQHERE HILGAA---------GAADPQRPI---------------------------PPGLF---- -----VPE-----------------------------------CDAHGH---YAPTQCHG ST--------GYCWCVDRDGREVEGTR------------TRPGMTPPCLSTVA-PPIH-- ------------------------------------------------------------ -------------------------------QGPAVPTAVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIERLPLEGNTMRKTE AKAFLHVPA-KVIIGLAFDCVDKMVYWTDITEPSIGRASLH-GGEPTTII-RQDLGSPEG IAVDHLGRNIFWTDSNLDRIEVAKLDG-TQRRVLFETDLVNPRGIVTDSVRGNLYWTDWN RDNPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDVFSSQLCWVDAGTNRAECLNPSQ--P SRRKALEGLQ----YPFAVT-SYGKNLYFTDWKMNSV-VALDLAIS-KETDAFQPH-KQT RLYGITTALSQCPRG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERK------------ ----------------------------- >XP_791550.3 nidogen-1 [Strongylocentrotus purpuratus] ------------------------------------------------------------ ----------------MKLLL----------G-------IFAVLIAVV------------ ------------------------------------------------------------ -------------NCLPR----DQFFPFGEG---------TTD--KKLNRR-SKKPLTLS FRE-----------PFTFLGEE-QSLL--------------------------------- ---------------------------YIVRDGYVSFSS--------GARGSK------- -----IAPFHTKLKLI----------------RGQSSVWYR-TTVSSNEED------EII NLIQRNFRSR--GSTDF------------------------------------------- TTFSPSSFV-------------------------------IVTWENMA-VRNSDHEVI-- ----GTVTFQLILVADAMHSFAFFLYDEN-----NDYPRPD---------RIGSNIDAGF TSGKAH-NQWEFE-MVYTTEDNKAATLFEAMRD-----------------SNVGMNGMWA YKIDGR-----------MDGNIIPAVAY--------VPV--------------------- --ESLPQND--EPPQD-------------------------------------------- ------------------------------------------------------------ ----------------AVNIQL-----------D-N-------TFDVVLDFE----NQC- --TRETCSVD-GRCVPYPTGHCCACNEGFM--GNGIHCLSINDNGRMNGRVNGTINGVTI P------DEVYL-----------HTFIMGGGGRTFTAIS-PVPSSI-------AYSMQIL ------LPIGELMGW----MFAEPAA-KGINGFMQTGGDLLYSANIRF-ENGDEVSI--- -------------IQRYTGVDESEEG--GGVIGGYVTIDGNVPNLSPGTSVSVDRHSEVY TKYRPGYVYSSE----QRSLD---------ADGQTIRFSIEQTITYQE---C-------- -EADDINTDA--SLTAMRMNTTYAYSIFEPQGDILRYAMIT------NVGPDIGVPT--- ---------------------------------DACQDNN--CG-TNAECFP-------- ---------------------------------QANTFTCRCRAGYTG-------NG--- ----YTCT---------------------------------------------------- ------------------------ESPSDPCDNNDCD--RNANCY-------PAGNSYTC QCNTGFN---GDGRVCVADQ---ASDPCDTNDCSLYA-------------YCYPTNDG-- ------------------------------------------------------------ -------------------QSFYCQCATGFTGDGRNCER--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------EQRG-------------------------------------- ------------------------------------------------------------ ---------------------------------------------NACD----------- ------------------------NNNCSP--YAYCRPRGDT-DFTCEC-------APGY VGDG-YNCEEE--------SQDP----------------C--LNNRCHPYADCSPVP--G GYTCSCRS------GYQGDGYLCEE----------------------------------- --------------------------------------------ADQLVNLCSDCGRDAD CL-------------PEGRGYRCI---------------------------CRAGFNGDG LTCEDVDE-----------------------------------CLEGADIACDANARCQN NR--------GSYTCRCNAGYRGDGFT--------------------C------------ ------------------------------------------------------------ --------------------------------------EALPEADG-------------- ------------------------------------------------------------ ------------------------------------SLVFGQGMSVMNLPRDGSA----- GNKVYMKSR-QTVVGLGYDCRHEYVYWTDISGRAIMKASLD-GRDVSVVV-NTSLSSPEG VAVDHLSRNLYWTDSGFDRIEVANLDG-TNRHVLFDTDLVNPRAIVIDPVGGYLYWVDWD RSYPRIEVSGMDGSGRAVFLD-EDLIMPNGLTIDLVSQLLCWADAGTQKVECMNLDGDPL SRYPVYRPAQ----YPFGLA-SLGNNLYWTDWQTSNI-QFINKNGG-EVQSLALPRGGNG RTYGIAAV-TQCTDG--NNRCAYENGGCR--NLCLPA---PGVRATCVCPNALAPN---- DIPCN------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------- >NP_001256467.1 NIDogen (basement membrane protein) [Caenorhabditis elegans] ------------------------------------------------------------ ----MKH---------KKMLI------------------LLFLYLLIE------------ ------------------------------------------------------------ -------------TTTAN----PAFYPYGQP---------AGD--NRLDY--SMEQSAIA LKI-----------PLTYMEQS-VDEL--------------------------------- ---------------------------FLSHNGIVGLGK--------PTPE-KIGGL-MT ISTPAIAVFYVPV--------------------TSGVIDYRVSSDDQGLLT------KLT QDVKQVFADA-------------------------------------------------- VEFHGLQAV-------------------------------IITWTQIE---NAEKD---- ----GPASFQLAIVSDGISTYAIFRYES--LPWSS---------------SMGYYAQAGF VR---------SIGKIQTNVNSGGPDVKELVNL-----------------SNNQFGNFFI FRVSGS----------AIEDPKDEGADD-------------------------------- ----YDYNNY-DQEYEG---------EHPADCPKDKFVDNCPAEC------RTVRDERGC ERCICAERPHAPR-------------APQEPRPELENTV---EDDE------------DD EQVDGTRYE-------EPARQAQEQHHQQHHQPD-QPQQQPQ-RSQEGSLPK----MSCS QRDDKSCHAN-SVCQDFEGGFCCNCDTGFY--GNGKECLPKGEPQRISGSFEGVINR--- ----IPIDKTEL-----------HTFATSTDGNVHTAVS-KIPSDL-------GHPLRFL ------YSIGGVMGW----LFADVQSPNVYNGFQLTGGLFNRTVALHI-EQNYYVTI--- -------------KQEFSGRNIH------DYFKSHLFVSGTLPDIAPGSEVIFPDYEEEY VRERRGYLTSKA----AFDVIVRDG-----GNVQTYRMSVDQQITFEE---C-------- -PNKEFDRDH-----SMKLHVKRINVVYNDDEGVVRYGAKNFA--TRSVGPAVSAPS--- -GGHFDRRQHGQSNMASERPIEIPSQSESISTDSVCAPGRHQCTLPNMKCRV-------- ---------------------------------VDPSYRCECEPGYQAAHDASSHIG--- ----WICQ---------------------------------------------------- ------------------------DLDECQRGDHNCD--QHAKCT-------NRPGSFSC QCLQGYQ---GDGRSCIRE-----HQASHHEHNQQT------------------------ -------------------------------------------------------PQE-- -----------------------------MAGVGA------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTEGF------------------------------------- ------------------------------------------------------------ -----------------------------------------------CT----------- -----------------------AHNQCHQ--WGECVFTSEHPTGRCKC-------RGWY VGDGVNHCGP----------PEENMPKHNANIPQRGGQAC--GSYVCDVNAECMPEPS-G GSECVCKA------GFSGNGVTCESL---------------------------------- --------------------------------------------LDDRHAHSSHNRHEQQ QQTGSL-----------------------------------------------------G KVCRSHDE-----------------------------------CSEHGS------CAYHH SL--------GYYQCACTEPYVGNGVE--------------------C------------ ------------------------------------------------------------ -------------------------------TLPGSSASAESSTRS-------------- ------------------------------------------------------------ -----------------------------------DKLLVARGMAIFERSTNPDE----Y GKQLIVIPH-HIPVGIDFDCKEEKIVWSDMSGHSIRTSSLN-GTEHKSYF-NKELSSPEG IAVDWSSRNVYYADSMNDEIGVASLNG-KFKKSLVTEGLVNPRSVVLDLYGRHLYYSDWH RENPYIGRVDMDGKNNRVFLN-EDVHLPNGLTILPNRRELCWVDAGNHRLSCIQYNG--A GRRTVFSSLQ----YPFGLTHDEEQKFYWTDWKDNRI-HSVGVYGE-GYRSFQISLGGSG KVFGILAVPKSCVGP--STPCSEDNGGCQ--HLCLPG---QNG-AVCECPDNVKV----- -KGC-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------- >XP_038046995.1 fibropellin-1-like isoform X27 [Patiria miniata] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MAW----LFALPSG-KGYNGFMLTGGKFRQTLNITF-STGEQMLI--- -------------TQDFQGVDEN------GYIRVIADWNGNIPEITPSDYVFVDDHKEEY VRHRLGVIHTFA----KRSLQV---------NDDTISYTMDQTIEYDE---C-------- -SADEADTEY--ILNFMRVSMTETYLIYEASEEILRFSMIG------KVTPASEQID--- ---------------------------------DPCVSNN--CD-RNAQCLPAGDSGFRC KCNEGYEGNGQTCTGSNPC-AQNSCDVNGYCIPQADRYTCACNAGYQG-------DG--- ----YTCSVD-RCASSRCDPNARCVETT-QGYECYCNAGFTGDGFRCQEE---------- ------------------------ESDHCA--NNNCD--PNARCV-------SAVFGYQC FCDPGYR---GDGYTCQANN---ATDPCANHTCDTNARCVASAQD-TYECYCFEGYTGDG FTCEVDPANPCAS--NTCDANARCVASAQDAYECSCLEGY---TGDGFTCEVN--PA--N PCAINT-CDANARCVASAQDAYECSCLEGYTGDGFTCEVNPTNPCAINTCD--ANARCVA SAQDAYECSCLEGYTGDGFTCEVNPANPCAINTCDVNARC-VATAQDAYECSCLEGYTGD GFTCEVAVDPANPCAINTCDANARCVASAQDAYECSCLEGYTGDGFTCNATDPCASN--V CDPNARCVAFSPAIYECSCLEGYTGDGLTCEANTTDPCVNNACDMNARCVASAQDAYECS CLEGYSGDGFTCMANTTDPCVNNACDTNARCVASAQDAYECYCFEGYTGDGFTCEAEQIN FCANNNCDRNARCVPTQTGYQCFCNQGYEGDGYSCRATQIDRCANNACDVNAYCVSTASA YNCYCNDGFSGDGFVCREIVDPCANNNCDV--NARCVPSQSG--YQCYC-------NQGF NGDG-FTCQAV--------SVDL----------------C--YNNRCDFNAECSPAQD-G GYSCTCNQ------GYEGDGFTCR------------------------------------ ---------------------------------------------NTLVNLCSACDASAQ CI-------------PEGRGFRCV---------------------------CRSGFQGNG LVCEDIDE-----------------------------------CSQSGA-ACHRYATCYN VR--------GSFSCYCQPGYEGDGFS--------------------C------------ ------------------------------------------------------------ ------------------------------------QEVTQPELDD-------------- ------------------------------------------------------------ -----------------------------------GALIYARGMAVMRVPLNANK----P GNKIVFRSG-QTIVGLGYDCQEEYIYWTDVSGRTISRAKAD-GSSTEVLI-SRGLSSPEG VAVDWLSRNMYWTDSGYDRIEVANLDG-SNRRVLLKTDMINPRAIAVDPIGGLMYWTDWN RDAPKIERANMDGSERSVLVD-SNLGLPNGLSLDYTTSQICWTDAGTKRIECMNMNGDPL TRFTVLPNSN----YPFSIA-SYGFKLYWSDWETKSI-QTISKTGGSESTDLKLPRGGNG RIYSVTAI-TSCPST--SNACSSNNGGCS--SLCLPT---QGGQRYCACPTNLEGN---- EVPCV------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------- >XP_031557799.1 nidogen-like [Actinia tenebrosa] ------------------------------------------------------------ ----MAS---------RNLVF------------------LLVLLVIQS------------ ------------------------------------------------------------ -------------SCLVLGARIQEFYPDGIDG-------PRGSS-ELLA---RRISPPVT LGT-----------TYNLYGKP-YTSL--------------------------------- ---------------------------RVYKNGLITLGEEPI--SFSPQKHRKFL---FP PEAKVIAPFYGQGDFT-----------------NTSRISYG-ETRDSDILT------RAS KDVKQSFSGE-------------------------------------------------- DEFNASAVF-------------------------------IVTWCQVKHAQHSQHK---- ----KNNTFQAVLVTNGDQTFVIFNYLTRGLQWAKGYHSQW------KG-AKYAYAQVGF SAGDFV--------RYSTLPGSGTNQVHWLASK-----------------SNMNTPGRWI YKVGWP----------GMHGNEVQSADS--------FEI--------------------- -DDSTNTDFFAAQFYDGCFVVHGYLTANRSQIWKDVSIRSCIALCF-ERRQKYAALHNGS QCACLNDIRHLIK-------------TNTDQDCDMACSV---NDDEVC-----------G GQMTASVYQ-------SVGLAAVQS--------D-----------QSGGQRKRKDVDECA V-GVVSCHAN-ATCINKSPGYCCQCNEGFY--GNGITCIEIGAVQRMVGFLSGTVNG--- ----EEFISLNM-----------DTIAFSDDGRAYVSVR-AFPPYL-------AHSARVL ------TPLTDVVGW----MYAKPKPSGFYNGYNVVGARFVRRASLRF-DSGEELAI--- -------------LQKYQGRDVL-----SHYMKVETTMNGAIPRIHPKAEVRMRKFRQEF QRTAAGRVQSRG----TVKYQV---------DGREHYFTVDQFIDYDEQKRCGQHVVRGV LEADVLTSNYDPAQAFLGIAVKGTFINTTLDSIDVQSQEADKMCGSKKVTCHTRGVCIQY RGDKECRCNHGY----------LGDGVTYCDDADECKLGRYRCA-PDADCVNTV-GSYRC VCKKGYVGDGKTCQKDSVIQCPRPCGANAKCVKIALGLLCNCNPDYQG-------DG--- ----FDCKPDGTCAGIKCDPNAKCATSSDKSRKCVCNDGYQGDGQTCTALEGRCGGVVCS TNAQCVQSKCVCNPGFQGNGKNCSDENECELKTHRCD--TNADCI-------NTVGSYSC RCRLGYQ---GDGLSCQKA-----SASCGGEKCHRFAYCDVDPQTKKQQCKCRRGFRGNG AEC-LD-FNECIPILKTCDVNALCR-NTLGSYECICKRGFIQGSDDDKTCIVD------D RCNGIK-CDVNARC----DRVQGCTCKTGFVGDGKTCNDIDECKSEMTRCD--PNADCRN TAG-SFTCSCRSGFEGDGVRCRVD--NSCDGVVCNVNARCEVQPDGRTRRCVCSNGWQGN GTLC--------------------------------------------TDVDECQSSRFS CPPNTDCINSNGS-YECRCKRGFEKKG--------------------------------- ------------------------------------------------------------ ----------SSCV--------------------------E---DDSCG----------- ------------------------GVTCDA--KARCVQTPQG-TRQCVC-------NTGW QKNG-NRCID----------KDE----------------C--QTNPCHPNADCINSI--G SFSCRCKP------GYNGNGQACND----------------------------------- --------------------------------------------VDECQSGQSRCPANTD CINREGSYECRCTTGFVSNGSSCIVDESCGGVKCDPNAKCIQIAQGVRQCVCNAGWEKNG NTCIDVDECRASISPCHSNANCINSIGSFSCRCRPGFKGDGQFCEDDGT---CGGVQCHP DASCHKNTA-EGTRCVCKPGYLGDGRK-CADIDECIQGKDECHEHATC--TNS-AGSYKC SCNLGYVGDGFNCTDDGSCQG--IDCDPNAKCVASSPTDGNRTCVCNDGFSGNGELCRDV DECDLGHAKCHRKAECVNQVGSYRCRCIRGYVGDGKQCESDGTCEGKVCDFNADCVTTNT TRGIDKTCKCKDGFSGDGVICTDVDECIKDPCPPMSQCVNAFGTYVCQCKPGYKKSNGLC EKICTRCRNGGSCIGENECKCPKGYSGNVCQWYGEASLIYTKGNSVQRMSLPPRS---NA IGLVYNHEG-MVNVGLDYDCVEEYIYWTEVMEGCIMRAKYD-GTNRELVFQRSEVRSPEG LSVDWIGRNLYWTDSGLDVIEVSRLNG-SNRKVLISNGLYDPRAILVDPPSGKMYWSDWT RRRPRIETADMDGTNRRVLVY-DDLGLPNGLTLVQTTNELCYTDAGSWSIRCVDLAG--L NVRKVLTRVT----YPFGIA-YFNRTLYWTDWNQNLI-HRIGVESSTPDSSLATFVGKTG KIFDVKAV-QPCPAKVPRNPCSDKNGGCL--GLCLLK---PHGGYTCSCPKGQFPVKDGN QTTCR------GKCDDPLGMEKGLISDAQLTASSAWSNNPK----------RHGAHRARL NLDTWPA---------------GWSTKKFDPKPWVQIDLGTHTMVTGVATQGLGKSIGEW VKTYRVAYSDDGVTWYVLR-NGGRKKIF--------VANSDSTTVKRNKFP-----AALK T-----RWLRILPRTWHNHVSMRLELYGC >XP_039259166.1 nidogen-like [Styela clava] ------------------------------------------------------------ ----------------MKTVA------------------VLLAVFAVG------------ ------------------------------------------------------------ -------------QSAVF----NDFYPFDRE----------ND--HRVPKGDNTSSPQFE LDL-----------PIIFYDSV-YNGI--------------------------------- ---------------------------KVNADGFVTLGV--------VEHEIE-----EH LLEPVLVPFGFNLNNT-----------------DASEIYYQ-EHKDEATLS------RAT NDIQKAFVETA------------------------------------------------- EAFVAKSAF-------------------------------IVTWVRLE-SPEHPG----- ----LTFTFQCVVVSNHLSSFAIFLYADDELAAGQSEEI-----------RNQLIAKAGF SDKGGD--------------QLESMTATELLEG-----------------GNAWSTGEWI FQIGGVLLS-------LEEEEEIPSHHLK------------------------------- -AEPIHHRR--ESGFE-------------------------------------------- ------------------------------------------------------------ ----------------VPEVNFNE---------D------------YGSD-Q----QDC- --DSLECDPEFSTCTAFADGYCCQCSEGSF--GNGYACIREDDDVRYNGQVDGYSIVMSD PWSNETAKGVDM-----------HSYVVTKDGRAFSVMNGEISAKL-------YRALQPM ------AIFGTTLGW----LFAQAEA-PAINGFQYSGGKIVSETYIRYTTGQYEFRI--- -------------RQEYDQVINDPEGGEGKVLNGRMTFSGRLPPVEEGENINVDDYTQIY KRTGADSIRSRD----TRRYIVGDT---------EHIFTVDQSIRFEG---C-------- -EASFEE-----VPADLAVDVSEVFLKFFPDENNLRFAVNS------RIRPAEEVG---- ---------------------------VRPVE-PSIIPDTPVPD-TPVPDTPE------- -----------PTPSETPVEKPEEPEIPEVVVTPATQTVCERQLQQVQQFQREN-PGIVD EIFFPTCT---------------------------------------------------- ------------------------DVGTFA--PRQCL-TYNSICWCVDEDTGEEIHGTRT EPLVGYQLDCSDVRAPPPA-----QTP--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CQED-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------RSNAETD----------------RI-------VAGS EANS------I--------FMPR----------------C-MESGAYEP---VQQLPD-G SFMCV---------DFDGEEISRS------------------------------------ ---------------------------------------------TEMPNCLTPCQLAAY VAESSNIF------------------------------------------LETNEF---- -----VVR-----------------------------------CKADGD---YNPEQCVE ----------TYCYCVDENGLEITNSR--VETTFGEDVDLDCGKFNSKPVTST------- ------------------------------------------------------------ ------------------------------VTTPTTTTGPIVGQEV-------------- ------------------------------------------------------------ -----------------------------------RRLLFAQTMGINVIDLPVTR-ENSV SRRLFARSD-QITIALGYDCSSKKYYWTDVSKRRIYSSVLDGDGSRAQFL-GDRLRSPEG ISVDFLSGNVYWTDSEYDRIEVASADG-SNRMTVVSGDIVNPRGIAVDPIRGRMYWTDWN RKAPKVWVANMDGSDRRVLLS-EGLGLPNDITIDFYRQRVCFVDAGTFKVECMSLNG--E GRETIYQMKQVPRPHPFGLA-VDGDVLYYSSWGGSKVVHAVNWRTG-DSIAIAGPRGAHG QMYGVEIAHSQCPRG--YNYCSSNNGGCS--HLCLPT---PTG-RECVCPPGAQD----- ---CQ------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------- >ACK77669.1 RE69505p [Drosophila melanogaster] ------------------------------------------------------------ ----MPTFG-------SKLLACL----------------LLSSVILVSG----------- --------------------------------------------QF-------------- ---------EHYLDSLRA----SELYEFEDGS--------LGSI-HLLPKG-DSETIVLQ LEQ-----------PIHFYGEQ-YEQL--------------------------------- ---------------------------YINTNGILTFNS--------EFPE-YLNQP-FP LEYASIAAFYSNVDTSF--------------SDEGTSISLF-ESKEQSILD------RAS SLVRYAFSSQ-------------------------------------------------- SEFEARQVI-------------------------------VATWRNVG-YFDSKTD---- ----RLNTFQVALIANEQSTFVQFIYPDGGLNWLQGETAGL-------G-LPDIRAQAGF VA---------EDGRFYTLNGSGSENARFLSES-----------------TNLGVPGVWL FEVAPI----------ENEQNVRSPDNA-------------------------------- -----------ESLTE-------------------------------------------- ------------------------------------------------------------ ----------------SPALAL-----------------------------------SCQ A-HAHQCHEK-AECHDKAEGYCCVCGSGFY--GNGKSCLANDQPIRVTGTLTGELNK--- --QPVS-EEAKL-----------QSYVVTSEGRTYTTIN-PLTPEL-------GAQLRLV ------LPLLTTVPW----LFAKSVG-GVANGYQLTGGVYTHVSRLQF-DSGENLHV--- -------------NQTFEGLNYW------DQLSVKIEIYGEVPAVAADAVLILPDYVEEY TFERPGELKSVQ----VLNINITE-------EQRVLGLQVEQRILYRS---C-------- -LRDDEADP---SATKVLQKISKVALDYVERDQALRIGAMS------KVGVTPES----- ---------------------------------NACNDGTADCV-ENSVCVP-------- ---------------------------------YEDTYRCDCYHGFAAQLDE---RGV-- ----EVCL---------------------------------------------------- ------------------------DIDECATGSHVCD--ENAVCD-------NTEGGFNC YCTEGFE---GNGYRCLSN-----STADNIEYPPAVEGQAEPTSEPSPNPSPYPDQGQD- ----------------------QEREREDDQYP----------QPNPYPYPEEQIPQHPD ECYR---CSKDADC-----YQGRCTCHEGFDGDGYTCTNI-------------------- ---------CGHGEVWE-------------------NGRC-------------------E PLLLE------------------------------------------RHDVDP------L CDALGECR----------CPYGYELSE--------------------------------- ------------------------------------------------------------ --------DSQRCT-------------YVQEFDGERNADL-----IPCD----------- -----------------------VDENCHI--NATCNWYGQELRHICTC-------QPGF RGDG-YNCDPI--------SDDS----------------CAIRPDICDVHADCVYEEHLG KSECQCQA------GYTGNGFNCQ------------------------------------ --------------------------------------------------LAAECQSAEH CGENAF-----C------DDGVCR---------------------------CQADFER-- ----DVSD----------------------------------RCVPAGR---CGSVFCGS NAICKWDSAEGVQYCDCLDGYQGDALTGCTSKPLSCHVLNNCGIHATCEPTED-PASYEC QCIAGFKGDGYVCIEEQNCLNNPTLCDMNAQCRSTN---SGLVCVCNQGF---------- -------------------------------FGNGSLCQERQHQDS-------------- ------------------------------------------------------------ -----------------------------------DFLIVSQGVMIARVPLNGRNVRP-- -----ISVA-QMAIGLDKDCVEGRVYWGDISTKKIVSTKYD-GTDLRPFI-TTDIESPEG IAIDVISRRLYWADSAKDTIEVASLDDPSLRAVIINKQLVNPRGIAVDPYREKLFWSDWD RESPKIEMSNLDGTGRELLLGKDDVTLPNSLVVLENSGEVCYADAGTKKVECIEPQN--R QIRTISNELS----YPFGIT-FTHDQFYWTDWTTKKV-EIVDSLGA-RQTPIQPPFFGSH KMYGMTVVEQHCPQY--QSPCQISNGGCTDSRLCLVNRQAPSG-KSCKCTSASTG----- ---CTVL----------------------------------------------------- -------------------------------AP--------------------------- ------------------------------------------------------------ ---------------------------GY >KAG9432604.1 nidogen-2 [Apis mellifera carnica] ------------------------------------------------------------ ----MTRRA-------CRLSVSW--------------PALVLATLVIA------------ ------------------------------------------------------------ ----------PFAVALNK----NDLYPYSIP---------GTSILQTDPNG-LLLSAETI LKT-----------PIAFYDQI-FNSI--------------------------------- ---------------------------FVNGNGVLSFAR--------AMHR-FFNIA-FP LDDPVIAPLYTHVDTR-----------------GSGRVYYG-ETDAPEILA------RAG GMVRSAFTDA-------------------------------------------------- ADFVPTHAF-------------------------------LATWVDVG-YYNGKSD---- ----KVNTYQVAISSNGTHSYVELLYPDDGIQWIQGESHPN-------G-LPDAKAQAGL MS----------EGRMYTLRGSGTDQIQNVDKW-----------------SNVNRPGQWV FQVGPI----------SDEEDIKVPDNV-------------------------------- -----------EDSSA-------------------------------------------- ------------------------------------------------------------ ----------------TNEVA------------------------------------NCR T-GATACHSK-ATCVDYEVGFCCHCKQGFF--GNGKSCQPNDVPLRVNGRISGTING--- ----VEFLARDL-----------QCYVQTKDGRTYTALS-RVPEEI-------GASFQLL ------GNLGGVIGW----LFAKPIG-ETKNGYELTGGLFNHTAELTFPSTGDKVTI--- -------------RSNYLGLDVF------GQLKMQAQIEGTLPQLGRDTGLDYGDYDELY TRVQTGVIRSRA----ERVCKLAEG-----VESRELDFVQDETIYYNE---C-------- -PYLTVEPED----DTTRLKFFRGVTTYEATEGIIRFAVNT------KVAPLEEE----- ---------------------------------DPCIQGRETCG-DHSYCVV-------- ---------------------------------DGDSFKCVCNPGYQYLYEE---DGS-- ----AICI---------------------------------------------------- ------------------------DVNECTAGKHMCS--PDAQCI-------NQEGSHTC QCRPGFS---GDGRTCDKLPSCEDTRCDNYEQCVMIEG--------APNCICLPGF---- ------------------------EDTEQGCYP----------ATQRAPCDVE------D NCSPNGFCNIDAE-----KQKYVCVCLPGFIGDGYTCYPDA----EVTTTDEPPKPQCIE EM-----CWCSSGWEYR-------------------NNEC-VR--------------QEE ETRTA------------------------------------------DYDRDL------S ARPLPECYEDN-----CICPWGHNYDR--------------------------------- ------------------------------------------------------------ --------SKEICVP---------RPGYKHETMGPSGVHL------SCN----------- -----------------------VMNRCHP--YAQCIYVTSTADYECRC-------NQGY EGDG-MECIK----------TEVS---------------C-LEVDICDPNASCQQEE--S LAKCVCNP------GFEGDGTMCS------------------------------------ --------------------------------------------------PIDECSSSSY CLENER-----CLYNSASSRYECT---------------------------CNPGYSM-- -----VDS----------------------------------RCVVSDC--STNPSQCHV NAQCT-SIGEGGYRCVCAEGYNGDGIRQCVEDHIGCNVLNNCGRNAVCGYNQT-SANFVC VCQQGYYGDGFTCLPQSSCRHDPAICSPDATCVAAG--ENQYACVCNEGF---------- -------------------------------VGDGTNCKSRPKHEA-------------- ------------------------------------------------------------ -----------------------------------NFLLVNQGMATLRIPFAPTY--EDP GSPIYIAYM-QMAIAIDIDCMNGKAYSSDISGNRIIELTYN-GSMAETFL--PKVSNPEG LAIDWVSRNIFWT--GKTTVEVANLET-KKRKVLVSDGLVNPRGIAVHPYRGKIFWSDWN RASPKLEWANEDGTDRAIFLQGDYVKLPNSLSIDWAMDELCWADAGTFTISCMEIDS--R KINVVANQLT----YPFGLA-ISQQHYYWTDWKTHKI-EVAMKSTGDRKQAISVPPGGSG KLYGIVVVPESCPRV--TNACQFEGGRCSKDQLCLPNG--QNG-RSCVCADDADG----- --PCT----------DNL------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------- >CAE1252257.1 LRP4 [Sepia pharaonis] ------------------------------------------------------------ ----MCRSPP---PPNKKAIPSCISSSPDEAGNKQGMKAIVTIIIAFGYFYVLNATNCQC PENMFNCGDSKCTCIQQSWVCDEDQDCVNRNDEKYCKHPSCSSLQFTCSNHKCIKKDWQC DGDNDCGDDSDELDCMTKNCT-DEEFRCDNGRCILVQWKCDGD--DDCKDGSDEHCDQEE CSQTDIRCGDGKCIPKAWICDEEVDCLDQIDEINCEFRKITCKSDEMYCPGSRRCIRARL KCDGQNDCGDWEDEIDCGNATLCHKGEFRCENGACINGTWRCDGEF-DCHEKSDE---FD CPLPSCSPRKFQCHTGHCIESSWHCDGHADCDDGSDEANCDIENCSSGQFQCRSGKCIGS NKVCNGLSECPDGSDEMHCNLPPSCRENNGGCNQNCLQTSRGARCSCYMGYHLQRDGKTC IDFNECEMVGACSQVCTNHPGSYKCSCATGYILKPDGRGCKATGGEVNLIFANRIEIRKG NP--SKSEFSFILDNLDNAIALDFHY-DLGLLFWSDVSLDVIKRVYLNGSNIQTIVECGL KNTGGLAVDWIHDKLFWTDSGTSRIEVTELDGADRRVLVWKGIDKPRAIVAHPGKGMIFW TDWGSSPKIESSGMDGHERRTIVNSSLI----WPNGLTI--------------------- -DYAAGKLYWADAKYH---------------VIECAYLDGSYRRT--------------- --IISHGLPHPFA-----------------------LTL---FEDELYWTDW-----HTR SIWRANKFT-------GNRVERVRSR--LHYPMD---------IHTYHPLRQPQAMNRCG S-DNGGCS---HLCLPTKRNYICACPTGLALRKDGKTCRD-----RLDNFLLFSTKSDLR R---ISFDTAEMIDMIIPLPNVQNVVAVEWDSDTNTILWTDVSTDTINRAKWDGSQAEVL IDSSLDSPAGLAVDWVGNKIYWTDQG-TNVIEVANSDGLFRKVLIWENLDKPRDIVLEPY ARYLFWTNWGHEPKIERAGMDGN----------GRTVLVSSNLTLPNGLSVDVKSSRLYW TDAGTQTIESATFDGLYRRIVIGVG-----LPHPFGLIVYEDSIFWTD------------ ---------------WNTKSVQMASKFNGTNHQTLKKGLDNVM----DITVFHRGR---- ---------------------------PYLS--TPCRKGNGGCS-HLCLLAP-------- ---------------------------------GPKTHTCACPTGILI-----KPDG--- ----KTCE---------------------KEMKNFLIFTRRNDIRKISM----------- ------------------------DVDYFADVVVPLGHLKNAVAL--DIDPLQGMIYWSD TVVDKIQRSNLDGSQVEDVI----SHGLDTTDGLAVD----------------------- ------------------------------------------------------------ -----------------------------YIGKKIYWTENG------------------- ------------------------------------NNRIEVA----------------- ------------------------------------------------------------ ------------------NLDGTMRKVL-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------FWQNLDSP-RAIVLHYEAGYMYWTDWGNQPRIERADM DGNNRLTVIANDLGWPNGLTIDKETRR------------L-IWNDATTEVIECSDLN--G NFRKVLVSKLLHPYGLTVAGRYIF------------------------------------ --------------------------------------------W---TDWRTRSIHRAD KITGEDV--------TVIRSNIPGLMD------------------------LRAVY---- -----IDK---TDHP--SN-----------------------RCGQSNG---GCSHLCLP NP--------QGYSCVCPTGLLL------------------------------------- ------------------------------------------------------------ -------------------------------TQDGKTCQSMPS----------------- ------------------------------------------------------------ -----------------------------------VYLLFASRGSIRRISLDSHD----Y TDVYIPLPDVHNAVALDFDIQESKIYYTDVTLDVIRRASLN-GSNMEEVI-HKGLSTTDG LAVDWVARNIYWTDTGRDVIEVARIDG-TSRRTLVSENLDEPRAVAVFPKKGFMFWTDWG K-SPKIERAYLDGTSRKAIVT-NDLGYPNGLSIDYVTKHLYWVDAQLDKIEMSDLNG--K NRIEIIRDVP----HPFGLS-VFGDYIYWTDWRTKSI-HRANKMTG---LNRIVIQNNME GLMAISVVSPLRQTG--TNQCAIRNGGCT--HLCLAR---PNG-YKCACPTYPDS----- -RPCLVVPLISSSNDDDLFAKKS--SSTQGSHQSNRCNKSQIKAGLCQPEDGHEAESRHF STFVIPGVLSSAVIIGFIFILVMWKRQRRRSAP----EFITLTF-TNPSYQ---RTSTET IDTERQSHGSS--SWRLFRFDRAEEQLLMLPQNDEKLNNLDQVQCDRPDIPENNAHVALK AEKHCRKVLLTLPKKITNTTKTNLDFSSS >XP_546076.2 nidogen-1 [Canis lupus familiaris] ------------------------------------------------------------ ----MSAARRRGETAWTRALL------------------LQLLLVGPG------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPG---------HGD--LQLEPGDDRVSPALE LRR-----------ALRFFDKSDIDSV--------------------------------- ---------------------------YVTTNGIIAMSE--------PPAKESYPGV-FP PTFGVVAPFLADLDTT----------------DGLGKVYYR-EDLSPSVTQ------LAA ECVQRGFPEV-------------------------------------------------- -SFQPSSVV-------------------------------VVTWESVA-PYQGPSKDPEQ EG--KRNTFQAVLASSDYSSYAIFLYPEDGLQFYTTFSKKD---------ENQVPAVVAF SQGIQG-LFWKSEGA-YNIFANDRESIGNLAKS-----------------SNSGQQGVWV FEIGSP----------ATASGVVPSDVS--------LGL--------------------- -DDGAEYD---DEDYE--------------SVTHLGLGDVSTTPF-----PYEDPRRGDP G---TYSAPRVLS-----------------PRRL-PTER---HPGPPTERTR-------S FQPPAETFPQQ-----HAQVIDV----------D-EVEETGV-VFSYNTDSR----QTCA N-NRHQCSVH-AECRDFATGFCCSCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGNS P-VPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APIGGIIGW----MFAVEQD-AFKNGFSITGGEFTRQAEVTFVGYPGKLVI--- -------------KQQFSGIDEH------GHLTINTELEGHVPHIPFGSSVHIEPYTELY -HYSRGVITSSS----TREYTVTEPEQGGAASSNIYTYQWRQTITFQE---C-------- -AHDTSRPV---LPSTQQLSVDSVFVLYNQEERILRYALSN------SIGPVRDGS---- ---------------------------PDALQ-NPCYIGTHGCD-TNAACRPG------- ---------------------------------PGVQFTCECSIGFRG-------DG--- ----RTCS---------------------------------------------------- ------------------------DIDECSEQPSVCG--SHAICN-------NHPGTFRC ECVEGYQFS-EEG-TCVATV---DQRPINY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHDCDIPQRAQCIYMGGS-SYTCSC-------LPGF SGDG-RACQD----------VDE----------------C--QPSRCHPDAFCYNTP--G SFTCQCKP------GYHGDGFHCV------------------------------------ --------------------------------------------PG--EMEKTRCQLERE HILRAA---------GLTDPQQPV---------------------------MPGLF---- -----VPE-----------------------------------CDEHGH---YTPTQCHG ST--------GHCWCVDRDGRELEGTR------------TRPGMTPPCLSTVA-PPIH-- ------------------------------------------------------------ -------------------------------HGPSVPTAVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIEHLPLEGSIMQKTE AKTLLHAPD-KVIIGLAFDCVDKMVYWTDISEPSIGRASMH-GGEPTTII-RQDLGSPEG IALDHLGRNIFWTDSHLDRIEVAKLDG-TQRRVLFETDLVNPRGIITDSVRGNLYWTDWN RDSPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDAYSSQLCWVDAGTNRVECLKPDE--S GRRRVLEGLQ----YPFAVT-SYGKNLYYTDWKTNSV-VAVDLAIS-KETDAFHPH-KQT RLYGVTTALSQCPQG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERK------------ ----------------------------- >NP_001094625.1 nidogen-1 precursor [Bos taurus] ------------------------------------------------------------ ----MLATVRRSGAAWTRALL------------------LQLLLAGPG------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPE---------HGD--LELEAGDDLVSPALE LST-----------ALHFFDRSDIDSV--------------------------------- ---------------------------YVTTNGIIAMSE--------PPAKETHPGP-FP PTFGAVAPFLADLDTT----------------DGLGKVYYR-EDLSPSVTQ------LAA ECVQRGFPEV-------------------------------------------------- -SFKPSSAV-------------------------------VVTWESVA-PYQGPSKDPTL EG--KRNTFQSILASSDSSTYAIFLYPEDGLQFYTTFSKKE---------ENQVPAVVAF SQGLVG-LIWKSDGA-YNIFANDKESIGNLAKS-----------------SNSGLQGIWV FEIGSP----------ATASGVVPADVN--------LGL--------------------- -DDGTEYD---DEDYD--------------SVTRVGLEDAVTTSF-----PYEAPGRGDS G---TYNTPSDLS-----------------PRRM-ATER---PLTPPTEKTR-------S FQLPGERFPQQ-----QPQVIDV----------D-EVEETEI-VFRYNTDSR----QTCA N-NRHQCSVH-AECRDFATGFCCRCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGDS Q-VPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APIGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGHRDKLII--- -------------KQQFSGIDEH------GHLTIDTELEGRVPQIAFGSSVHIEPYTELY -HYSRQVITSFS----TREYTVTEPERHGTAPSHAHTYRWRQTITFRE---C-------- -LHDDSRPA---LPSTQQLSVDSVFVLYNQEERILRYALSN------SIGPVRDGS---- ---------------------------PDALQ-NPCYIGSHGCD-SNAACRPG------- ---------------------------------PGTQFTCECSIGFRG-------DG--- ----RTCY---------------------------------------------------- ------------------------DIDECSEQPSVCG--NHAICN-------NHPGTFRC ECVEGYQFS-EAG-TCVAAV---GLRPVNH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHDCDIPQRARCIYMGGS-SYTCSC-------LPGF SGDG-RACQD----------VDE----------------C--QPSRCHPDAFCYNTP--G SFTCRCKS------GYQGDGFHCV------------------------------------ --------------------------------------------PG--VVEKTRCQHERE HIL------------GTADSSRPR---------------------------PPGLF---- -----VPE-----------------------------------CDEHGQ---YVPTQCHS ST--------GYCWCVDRDGREVQGTR------------TRSGMRPPCLSTVA-PPVH-- ------------------------------------------------------------ -------------------------------YGPPVPTTVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIERLPLEGSTMTKSE AKTLLHAPG-KVIIGLAFDCVDKMVYWTDISQPSIGRASLH-GGEPATIV-RQDLGSPEG IALDHLGRNIFWTDSQLDRIEVAKLDG-TQRRVLFETDLVNPRGIVTDSVRGNLYWTDWN RDNPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDAYSSQLCWVDAGAHRAECLKPGQ--S SRRKVLEGLQ----YPFAVT-SFGKNLYYTDWKTNSV-VAVDLAVS-KETDSFHPH-KQT RLYGITSALSQCPEG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERK------------ ----------------------------- >XP_017203089.1 PREDICTED: nidogen-1 [Oryctolagus cuniculus] ------------------------------------------------------------ ----M-------RAAWMRALL------------------LQLLLAGPG------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPG---------QGD--LELEDGDDLVSPALE LSG-----------ALHFYDRSDIDSV--------------------------------- ---------------------------YVTTNGIIAMSE--------PLAKESHPGL-FP PGFGVVTPFLVDLDTT----------------DGLRKVYYR-EDLSPSIMQ------LAA ECVQRGFPEV-------------------------------------------------- -SFQPSSVV-------------------------------VVTWESVA-AYQGPNQDPIQ EG--KVST---------------------------------------------------- ------------------------------------------------------------ ----CP----------GTSSS--------------------------------------- ------------------------------HLTHCALCSFGL-KY-----PYA------- ------------------------------P----------------------------- ----------------YACVIDK----------H-ET-QSRI-LFS---KAV----EICF S-DD-----Q-TECRDYATGFCCSCVAGYT--GNGKQCVAEGSPQRVNGKVKGRIFVGTS Q-VPVVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APIGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGYPGKLVI--- -------------KQQFSGIDEH------GHLTIDTELEGRVPQIPFGSSVHIEPYTELY -HYSSSVITSSS----TREYTVTEPERDGTAPSHTYTYQWRQTITFQE---C-------- -VHDDSRPA---LASTQQLSVDSVFVLYNQEEQILRYALSN------SIGPVRDGS---- ---------------------------PDALQ-NPCYIGTHGCD-TNAACRPG------- ---------------------------------PGTQFTCECSIGFRG-------DG--- ----KTCY---------------------------------------------------- ------------------------DIDECVEQPSVCG--SHALCN-------NHPGTFRC ECVEGYRFS-DQG-TCVAIM---DQRPINY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CVTG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHDCDIPQRAQCVYTGGS-SYTCSC-------LPGF SGDG-RACQD----------VDE----------------C--QPSRCHPDAFCYNTP--G SFTCQCKP------GYQGDGFRCI------------------------------------ --------------------------------------------PG--ELEKTRCQLERE HILGAA---------GAADAQRPR---------------------------PPGLF---- -----VPE-----------------------------------CDEHGH---YSPTQCHG ST--------GYCWCVDRDGREVEGTR------------TRPGMRPPCLSTVA-PPIH-- ------------------------------------------------------------ -------------------------------QRPLVPTAVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIENVPLDGNTMKKTE AKALLHMPD-KVIIGLAFDCVDKMVYWTDISEPSIGRASLH-GGEPSTII-RQDLGSPEG IAVDHLGRNIFWTDSQLDRIEVAKLDG-TQRRVLFETDLVNPRGIVTDSVRGNLYWTDWN RDNPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDAFSSQLCWVDAGTNRAECLHPSQ--P SRRKVLEGLQ----YPFAVT-SYGKNLYYTDWKTNSV-VAVDLAVS-KETDSFHPH-KQT RLYGITTALSQCPQG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTMG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERK------------ ----------------------------- >XP_024106979.1 nidogen-1 [Pongo abelii] ------------------------------------------------------------ ----MLASRSRIRAAWTRALL------------------LPLLLAGPV------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPE---------QGD--LELEDGDDLVSPALE LSG-----------ALRFYDRSDIDSV--------------------------------- ---------------------------YVTTNGIIATSE--------PPAKESHPGL-FP PTFGAVAPFLADLDTT----------------DGLGKVYYR-EDLSPSITQ------RAA ECVHRGFPEI-------------------------------------------------- -SFQPSSAV-------------------------------VVTWESMA-PYQGPSRDPDQ EG--KRNTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKKE---------NNQVPAVVAF SQGSVG-FLWKSNGA-YNIFANDRESIENLAKS-----------------SNSGQQGVWV FEIGSP----------ATTNGVVPADVI--------LGT--------------------- -EDGAEYD---DEDED-----------YDLATTRLGLEDVGTTPF-----SYKALRRGGA D---TYSVPSILS-----------------PRRA-ATER---PLGPPTERTR-------S FQLAVETFHQQ-----HPQVIDV----------D-EVEETGV-VFSYNTDSR----QTCA N-NRHQCSVH-AECRDYATGFCCSCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGSS Q-IPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APVGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGHPGNLVI--- -------------KQRFSGIDEH------GHLTIDTELEGRVPQIPFGSSVHIEPYTELY -HYSTSVITSSS----TREYTVTEPERDGASPSHIYTYQWRQTITFQE---C-------- -VHDDSRPA---LPSTQQLSVDSVFVLYNQEERILRYALSN------SIGPVREGS---- ---------------------------PDALQ-NPCYIGTHGCD-TNAACRPG------- ---------------------------------PRTQFTCECSIGFRG-------DG--- ----RTCY---------------------------------------------------- ------------------------DIDECSEQPSVCG--SHAICN-------NHPGTFRC ECVEGYQFS-DEG-TCVAVV---DQRPINY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHNCDIPQRARCIYTGGS-SYTCSC-------LPGF SGDG-QACQD----------VDE----------------C--QPSRCHPDAFCYNTP--G SFTCQCKP------GYQGDGFRCV------------------------------------ --------------------------------------------PG--EVEKTRCQHERE HILGAA---------GAADPQRPI---------------------------PPGLF---- -----VPE-----------------------------------CDAHGH---YAPTQCHG ST--------GYCWCVDRDGREVEGTR------------TRPGMTPPCLSTVA-PPIH-- ------------------------------------------------------------ -------------------------------QGPAVPTAVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIERLPLEGNTMRKTE AKAFLHVPA-KVVIGLAFDCVDKMVYWTDITEPSIGRASLH-GGEPTTII-RQDLGSPEG IAVDHLGRNIFWTDSNLDRIEVAKLDG-TQRRVLFETDLVNPRGIVTDSVRGNLYWTDWN RDNPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDVFSSQLCWVDAGTNRAECLNPSQ--P SRRKVLEGLQ----YPFAVT-SYGKNLYFTDWKMNSV-VALDLAVS-RETDAFQPH-KQT RLYGITTALSQCPQG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERK------------ ----------------------------- >XP_020929417.1 nidogen-1 isoform X1 [Sus scrofa] ------------------------------------------------------------ ----MLAAIRWSQAAWTLALL------------------LQLLLAGPG------------ ------------------------------------------------------------ -------------GCLSH----QELFPFGPG---------HGD--LELEAGDDLVSPALE LST-----------ALRFFDKSNIHSI--------------------------------- ---------------------------YVTTNGLIATSE--------PPAKEAHPGL-FP PTFGAVAPFLADLDTT----------------DGLGKVYYR-EDVSPSTTQ------LAM ECVQRGFPEV-------------------------------------------------- -TFKPSSVV-------------------------------VVTWENVA-PYQGPGKDPAQ ED--KRNTFQAVLASSDASSYAIFLYPEDGLQFYTTFSKKD---------EDQVPAVVAF SQGVVG-LIWKSDGA-YNIFANDRESLGNLAKS-----------------SNSGQQGVWV FEIGSP----------ATASGVVPSDVN--------LGL--------------------- -DDGTEYD---DEDYD--------------SVTGVGLEVVGTTSF-----PHETPRRGDA G---TYNMPSDLA-----------------PRRL-ATER---PPTPPTERTR-------S FQLPAETFPQQ-----QPQVIDV----------D-EVEETGV-VFSYNTDNR----QTCA N-NRHQCSVH-AECRDFATGFCCSCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGNS P-APIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETI-------GYSLLPL ------APIGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGHPDKLVI--- -------------KQQFSGIDEH------GHLTIDTELEGRVPHIPFGSSVHIEPYTELY -HYSRQVITSSS----TREYTVMEPEQDSTAPSHVHTYQWRQTITFQE---C-------- -VHDDSRPA---LPSTQQLSVDSVFVLYNQEERILRYALSN------SIGPVRDGS---- ---------------------------PDALQ-NPCYIGTHGCD-TNAACRPG------- ---------------------------------PGTQFTCECSIGFRG-------DG--- ----RTCY---------------------------------------------------- ------------------------DINECSEQPAVCG--SHAICN-------NHPGTFRC ECVEGYRFS-EEG-TCVAVV---DQRPINY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHDCDIPERAQCIYLGGA-LYTCSC-------LPGF SGDG-RACQD----------VDE----------------C--QPSRCHPDAFCYNTP--G SFMCQCKP------GYQGDGFRCV------------------------------------ --------------------------------------------PG-AEVEKTRCQLERE HLL------------GPADAQRPW---------------------------PPGLF---- -----VPE-----------------------------------CDEHGH---YAPTQCHG ST--------GYCWCVDRDGREVEGTR------------TRPGMRPPCLSTVA-PPIH-- ------------------------------------------------------------ -------------------------------HGPAVPTAVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIERLPLAGSTMTKTD AKALLHAPD-KVIIGLAFDCVDQMVYWTDISEPSIGRASLH-GGEPTTIL-RQDLGSPEG IALDHLGRNIFWTDSHLDRIEVAKLDG-TQRRVLFDTDLVNPRGIVTDSVRGNLYWTDWN RDSPKIETSYMDGTNRRVLVQ-DDLGLPNGLTFDAYSSQLCWVDAGTSRAECLKPGQ--P SRRKVLEGLQ----YPFAVT-SYGKNLYYTDWKMNSV-VAIDLAVS-KETDTFHPH-KQA RLYGITTALSQCPEG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------EQK------------ ----------------------------- >XP_031408053.1 LOW QUALITY PROTEIN: nidogen-1 [Meleagris gallopavo] ------------------------------------------------------------ ----MSA--------VRRRAPCGR-------------PASRCAPSTPR------------ ------------------------------------------------------------ --------------FPSY----RSCSQHQREG--------RAG--GCRQTPPRLRTPALW CER-----------RRRLMRAG-LEVL--------------------------------- --------------------------ATVATNGIIAVNE--------PKNEENYLGQ-FP VSFGAIAPFMADLDTT----------------DGRGSVYYR-EDSSSDVLQ------LAS DYIKGGFPEA-------------------------------------------------- -AFDPSSVV-------------------------------IVTWKLVA-PYQGPGEDLTL EE--KRNTFQAVLASSDSSSYAIFLYPEDGLQFYSAYSKNN---------DGKIPAMVGF SQASTNYYFWENPGS-YNVIANDEDSIRNLHKS-----------------SNAGRQGVWV FEIGSS------------SDTIVPAKVS--------NVL--------------------- --ASLEPS---EEDQE--------------LTSKPFMSDYGSTEIRPQYVTSSTDSTEED Q-HVTYSVPQLAV----EDFITSYQDVTGTPSTE-SFYR---HREFPTAKAP-------P RQFPAQQFPPQ-----GPQVIDV----------E-EFDETGI-VFRYHTDVQ----QTCA N-NRHQCSVH-AICKDYPNGFCCSCIAGYK--GNGRQCVAEGSPQRVNGKVKGRIFVGNN P-VPVTFENTDL-----------HSYVVMNHGRAYTAIS-TIPEAL-------GYSLLPL ------ASIGGVIGW----MFAVEQQ-GYKNGFSITGGEFTRQTEVTFLGNNEKVVI--- -------------KQKFSGIDEH------GHLTISTEMEGRVPEVPAGASVHIEPYTELY -HASSSVITSSS----TREYTVTEPERDGVASTYTGAYQWRQTISFDE---C-------- -IHDDTLHA---APATQQLSVDSIFVLYNRDEQILRYAMSN------SIGPISDGS---- ---------------------------ADISR-NPCYTGTHNCD-TNAVCRAG------- ---------------------------------SGNRFSCECSIGFRG-------DG--- ----NVCY---------------------------------------------------- ------------------------DIDECSEQAGACG--SNAVCN-------NQPGTYRC ECVDGYQFA-ADGRTCVAV-----EYAVNH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CQTG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------THGCDIPQRAQCVYTGGS-AYVCTC-------LPGF SGDG-RACED----------IDE----------------C--QQGRCHPDAFCYNTP--G SFSCQCKA------GYRGDGFQCV------------------------------------ --------------------------------------------LG--GVVKTKCQREKE VALGS----------GGTFFQREI---------------------------RVGQF---- -----IPQ-----------------------------------CDEHGN---YVPTQCHG ST--------GYCWCVDRDGNEIDGTR------------SXPGVRPPCLSTAA-PPVV-- ------------------------------------------------------------ -------------------------------IGPSVRPDTIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQSGKIEHVPLEGNSMKKNG AKALLHIPD-KVIIGVAYDCMDKMVYWTDISGPSISRASLH-GGEPTTII-RTDLGSPEG IALDHLGRNIFWTDSQLDRIEVARLDG-RQRRILFDTGLVNPRAIVVDPVRGNLYWTDWN REAPKIETSYMDGTNRRILVK-DDLGLPNGLTFDPYSSMLCWVDAGTKRLECMNPNQ--L GRRKIVEGIQ----YPFGVT-SYGKNLYYTDWRRDAV-VAVDRMVS-VENDNFQPH-KRS RLYGITTAFAQCPGG--HNYCTVNNGGCT--HLCLAT---PEG-RSCRCPDNTVG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERN------------ ----------------------------- >XP_003824554.1 nidogen-1 [Pan paniscus] ------------------------------------------------------------ ----MLASSSRIRAAWTRALL------------------LPLLLAGPV------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPG---------QGD--LELEDGDDLVSPALE LSG-----------ALRFYDRSDIDSV--------------------------------- ---------------------------YVTTNGIIATSE--------PPAKESHPGL-FP PTFGAVAPFLADLDTT----------------DGLGKVYYR-EDLSPSITQ------RAA ECVHRGFPEI-------------------------------------------------- -SFQPSSAV-------------------------------VVTWESVA-PYQGPSRDPDQ KG--KRNTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKKE---------NNQVPAVVAF SQGSVG-FLWKSNGA-YNIFANDRESIENLAKS-----------------SNSGQQGVWV FEIGSP----------ATTNGVVPADVI--------LGT--------------------- -EDGAEYD---DEDED-----------YDLATTRLGLEDVGTTPF-----SYKALRRGGA D---TYSVPSVLS-----------------PRRA-ATER---PLGPPTERTR-------S FQLAVETFHQQ-----QPQVIDV----------D-EVEETGV-VFSYNTDSR----QTCA N-NRHQCSVH-AECRDYATGFCCSCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGSS Q-VPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APVGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGHPGNLVI--- -------------KQRFSGIDEH------GHLTIDTELEGRVPQIPFGSSVHIEPYTELY -HYSTSVITSSS----TREYTVTEPERDGASPSHIYTYQWRQTITFQE---C-------- -VHDDSRPA---LPSTQQLSVDSVFVLYNQEEKILRYALSN------SIGPVREGS---- ---------------------------PDALQ-NPCYIGTHGCD-TNAACRPG------- ---------------------------------PRTQFTCECSIGFRG-------DG--- ----RTCY---------------------------------------------------- ------------------------DIDECSEQPSVCG--SHTICN-------NHPGTFRC ECVEGYQFS-DEG-TCVAVV---DQRPINY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHNCDIPQRARCIYTGGS-SYTCSC-------LPGF SGDG-QACQD----------VDE----------------C--QPSRCHPDAFCYNTP--G SFTCQCKP------GYQGDGFRCV------------------------------------ --------------------------------------------PG--EVEKTRCQHERE HILGAA---------GAADPQRPI---------------------------PPGLF---- -----VPE-----------------------------------CDAHGH---YAPTQCHG ST--------GYCWCVDRDGREVEGTR------------TRPGMTPPCLSTVA-PPIQ-- ------------------------------------------------------------ -------------------------------QGPALPTAVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIERLPLEGNTMRKTE AKAFLHVPA-KVIIGLAFDCVDKMVYWTDITEPSIGRASLH-GGEPTTII-RQDLGSPEG IAVDHLGRNIFWTDSNLDRIEVAKLDG-TQRRVLFETDLVNPRGIVTDSVRGNLYWTDWN RDNPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDVFSSQLCWVDAGTNRAECLNPSQ--P SRRKALEGLQ----YPFAVT-SYGKNLYFTDWKMNSV-VALDLAIS-KETDAFQPH-KQT RLYGITTALSQCPRG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERK------------ ----------------------------- >XP_003993948.1 nidogen-1 [Felis catus] ------------------------------------------------------------ ----MLAAIRRSGAAWTRALL------------------LQLLLAGPG------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPG---------HGD--LELEAGDDQVSPALE LRR-----------ALRFFDKSDINSV--------------------------------- ---------------------------YVTTNGIIAMSE--------PPAKESSPGL-FP PTFGVVAPFLADLDTT----------------DGFGKVYYR-EDLSPSVTR------LAA ECVQRGFPEI-------------------------------------------------- -SFQPSSAV-------------------------------VVTWESVA-PYQGPSKDPAQ EG--KRNTFQAVLASSDSSSYAIFLYPEDGLQFDTTFSKKD---------ETQVPAVVAF SQGVQG-FIWKSDGA-YNIFANDRESIGNLAKS-----------------SNSGQQGVWV FEIGSP----------ATASGVVPSDVS--------LGL--------------------- -DDGAEYD---DEDYD--------------SVTHLGLEDVGTTSF-----PYEAPRSGDP S---MHSVPWVLS-----------------PRRL-PTERPPGPPGPPTERTR-------S FQLPGERFHQQ-----HPQVIDV----------D-EVEETGV-VFSYNTDSR----QTCA N-NRHQCSVH-AECRDFATGFCCSCVAGYT--GNGRQCVAEGSPQRVNGKVRGRILVGNS P-VPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APVGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGYPGKLVI--- -------------KQRFSGIDEH------GHLTITTELEGRVPQIPFGSSVHIEPYTELY -HYSPGVITSSS----TREYTVMEPEQDGAAPSTIYTYQWRQTITFQE---C-------- -AHDTSRLA---LPNTQQLSVDSVFVLYNQEESILRYALSN------SIGPVKDGS---- ---------------------------PDALQ-NPCYIGTHGCD-TNAACRPG------- ---------------------------------PGVQFACECSIGFRG-------DG--- ----RTCS---------------------------------------------------- ------------------------DIDECSEQPSVCG--SHAICN-------NHPGTFRC ECVEGYQFS-EEG-TCVAVV---DQRPINY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CTTG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHDCDIPQRAQCIYMGGS-SYTCSC-------LPGF SGDG-RACRD----------MDE----------------C--QPSQCHPDAFCYNTP--G SFTCQCKP------GYRGDGFHCV------------------------------------ --------------------------------------------PG--EMEKTRCQLERE HILGAA---------GAADPPR------------------------------PGLF---- -----VPE-----------------------------------CDEHGH---YVPTQCHG ST--------GYCWCVDRDGRELEGTR------------TRPGMRPPCLSTVA-PPIH-- ------------------------------------------------------------ -------------------------------HGPSVPTAVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIERLPLEGSTMQKSE AKTLLHAPD-KVIIGLAFDCVDKMVYWTDISEPSIGRASLH-GGEPTTII-RQDLGSPEG IALDHLGRNIFWTDSHLDRIEVAKLDG-TQRRVLFETDLVNPRGIVTDSVRGNLYWTDWN RESPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDAYSAQLCWVDAGTSRVECLKPGQ--P SRRKVLEGLQ----YPFAVT-SYGKHLYYTDWKMSSV-VAVDLAIS-KETDTFHPH-KQT RLYGVTTALSQCPQG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERK------------ ----------------------------- >XP_011960995.3 nidogen-1 [Ovis aries] ------------------------------------------------------------ ----MLATVRRSGAAWTRALL------------------LQLLLAGPG------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPE---------HGD--LELEAGDDLVSPALE LST-----------ALHFFDRSDIDSV--------------------------------- ---------------------------YVTTNGIIAMSE--------PPAKETHPGP-FP PTFGAVAPFLADLDTT----------------DGLGKVYYR-EDLSPSVTQ------LAA ECVQRGFPEV-------------------------------------------------- -SFKPSSAV-------------------------------VVTWESVA-PYQGPSKDPTL EG--KRNTFQCILASSDSSTYAIFLYPEDGLQFYTAFSKKE---------ENQVPAVVAF SQGLTG-LIWKSDGA-YNIFANDRESVGNLAKS-----------------SNSGLQGIWV FEIGSP----------ATASGVIPADVN--------LEL--------------------- -DDGAEYD---DEDYD--------------SVTHLGLEDAVTTSF-----PYEAPRREDS G---THNTPSDLS-----------------PRRM-ATER---PLTPPTEKTR-------S FQLPGERFPQQ-----QPQVIDV----------D-EVEETGI-VFSYNTDSR----QTCT N-NRHQCSVH-AQCRDFATGFCCSCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGDS Q-VPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APIGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGHPDKLTI--- -------------KQQFSGIDEH------GHLTIDTELEGRVPQIAFGSSVHIEPYTELY -HYSRQVITSSS----TREYTVTEPEQHGTAPSHVHTYQWRQTITFQE---C-------- -VHDDSRPV---LPSTQQLSVDSVFVLYNQEERILRYALSN------SIGPVRDGS---- ---------------------------PDALQ-NPCYIGSHGCD-ANAACRPG------- ---------------------------------PGTQFTCECSIGFRG-------DG--- ----RTCY---------------------------------------------------- ------------------------DIDECSEQPSVCG--NHAVCN-------NHPGTFRC ECVEGYRFS-EAG-TCVADV---DLRPINH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHDCDIPQRAQCKFMGHG-SYTCIC-------LPGF SGDG-RACQD----------VNE----------------C--QPSRCHPDAFCYNTP--G SFVCRCKY------GYQGDGFHCV------------------------------------ --------------------------------------------PG--EVEKTRCQQERE RVV------------GTADSPRPQ---------------------------PPGLF---- -----VPE-----------------------------------CDEQGH---YVPTQCHS ST--------GYCWCVDRDGQEVEGTR------------TGSGMRPPCLSTVA-PPVH-- ------------------------------------------------------------ -------------------------------FGPPVLTAVIPPPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIERLPLEGSTMTKSE AKTLLHAPD-KVIIGLAFDCVDKMIYWTDISQPSIGRASLH-GGEPTTII-RQDLGSPEG IALDHLGRNIFWTDSQLDRIEVAKLDG-TQRRVLFETDLVNPRGIVTDSVRGNLYWTDWN RDNPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDAYSSQLCWVDAGTHRAECLNPGQ--P NIRKVLEGLQ----YPFAVT-SFGKNLYYTDWKTNSV-VAVDLAVS-KEMDSFHPH-KQT RLYGITSALSQCPEG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------EQK------------ ----------------------------- >XP_018887566.2 nidogen-1 [Gorilla gorilla gorilla] ------------------------------------------------------------ ----MLASSSRIRAAWTRALL------------------LPLLLAGPV------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPG---------QGD--LELEDGDDLVSPALE LSG-----------ALRFYDRSDIDSV--------------------------------- ---------------------------YVTTNGIIATSE--------PPAKESHPGL-FP PTFGAVAPFLADLDTT----------------DGLGKVYYR-EDLSPSITQ------RAA ECVHRGFPEI-------------------------------------------------- -SFQPSSAV-------------------------------VVTWESVA-PYQGPSRDPDQ KG--KRNTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKKE---------KNQVPAVVAF SQGSVG-FLWKSNGA-YNIFANDRESIENLAKS-----------------SNSGQQGVWV FEIGSP----------ATTNGVVPADVI--------LGT--------------------- -EDGAEYD---DEDED-----------YDLETTRLGLEDVGTTPF-----SYKALRRGGA D---TYSVPSVLS-----------------PRRA-ATER---PLGPPTERTR-------S FQLAVETFHQQ-----HPQVIDV----------D-EVEETGV-VFSYNTDSR----QTCA N-NRHQCSVH-AECRDYATGFCCSCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGSS Q-IPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APVGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGHPGNLVI--- -------------KQRFSGIDEH------GHLTIDTELEGRVPQIPFGSSVHIEPYTELY -HYSTSVITSSS----TREYTVTEPERDGASPSRIYTYQWRQTITFQE---C-------- -IHDDSRPA---LPSTQQLSVDSVFVLYNQEERILRYALSN------SIGPVREGS---- ---------------------------PDALQ-NPCYIGTHGCD-TNAACRPG------- ---------------------------------PRTQFTCECSIGFRG-------DG--- ----RTCY---------------------------------------------------- ------------------------DIDECSEQPSVCG--SHTICN-------NHPGTFRC ECVEGYQFS-DEG-TCVAVV---DQRPINY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHNCDIPQRARCIYTGGS-SYTCSC-------LPGF SGDG-QACQD----------VDE----------------C--QPSRCHPDAFCYNTP--G SFTCQCKP------GYQGDGFRCV------------------------------------ --------------------------------------------PG--EVEKTRCQHERE HILGAA---------GAADPQRPI---------------------------PPGLF---- -----VPE-----------------------------------CDAHGH---YAPTQCHG ST--------GYCWCVDRDGREVEGTR------------TRPGMTPPCLSTVA-PPIH-- ------------------------------------------------------------ -------------------------------QGPAVPTAVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIERLPLEGNTMRKTE AKAFLHVPA-KVIIGLAFDCVDKMVYWTDITEPSIGRASLH-GGEPTTII-RQDLGSPEG IAVDHLGRNIFWTDSNLDRIEVAKLDG-TQRRVLFETDLVNPRGIVTDSVTGNLYWTDWN RDNPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDAFSSQLCWVDAGTNRAECLNPSQ--P PRRKVLEGLQ----YPFAVT-SYGKNLYFTDWKMNSV-VALDLAIS-KETDAFQPH-KQT RLYGITTALSQCPQG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERK------------ ----------------------------- >XP_004077531.1 nidogen-1 [Oryzias latipes] ------------------------------------------------------------ ----MFWRD-------QGWLLWA----------------TFLGLVASA------------ ------------------------------------------------------------ -------------HSIRR----DEFFPFGES---------AGD--QVLEPENDR-TQRLD LSA-----------PLLFYDRS-FDSI--------------------------------- ---------------------------FINTNGFVATEE--------PPSESTYLGK-MP PSFGMIAALHGDLDTS----------------AGVGKVFFR-QDSRADVLR------RAA EHINRAFPYN-------------------------------------------------- DEVDPTHAV-------------------------------VVTWVDVA-PHTPHTRGDGL EK--KRNSFQLVLASLQKASYAILLYARDGVQFSSTLVQ-----------GSDVIVHAGF SKGQVPGFWFTSQGPYYRTTSDEEISVRELAEQ-----------------TNSGQRGVWV YEIGTS----------PTFSNVVPGEVT-------------------------------- -----------DLPTE--------------PP--PPLAQTTEPSW-----PLYTEYD--- ------------------------------PEQI-------------------------- -EIHSNQYQPLQPH--DPEVVVL----------D-ETDINVD-VFSYNFG-------TCS N-NRNKCSQF-ADCRDYSSGFCCHCRPGFY--GNGIQCVAEGKPQRMNGKIHGRVFVGSS P-YPVELGGVDL-----------HSYVVVNDGRSYVAIS-DIPETL-------GPSLLPL ------SVLGGVIGW----AFALEQP-GYRNGFSIIGGEFTREAEVTFMPWNEKLII--- -------------RQEFKGTDEL------DHLVVKTTLEGKVPEMPLGSTVTMDPYAEIY -QYGSNLITSSS----TREYKVTMPD----GSAETRTYQCRQTITFQS---C-------- -QHGDSLRD---VKPSQMLSVDQVFVLYDVNNKILRYAMSN------KVGDVNGGE---- ---------------------------PQ--Q-NPCFTGRHGCD-NNAVCRPG------- ---------------------------------QGSQFTCECAAGFLD-------NG--- ----RNCD---------------------------------------------------- ------------------------DIDECRENPQICG--YNAVCN-------NQPGTYRC ECEDGFQFG-SDGRTCVEV-----DRPVNH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CEEG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------THDCDAPERAQCSYTGSS-SFICSC-------LPGF VGDG-RNCQD----------IDE----------------C--QSRRCHQDADCFNTP--G SFVCRCRQ------GYRGDGSYC------------------------------------- --------------------------------------------YS--DRRRTRCEEERD SLLGGTV--------FGPRGPRP----------------------------S-ESH---- -----IPA-----------------------------------CDGNGE---YEPLQCDR RT--------GSCWCVDRNGVEVRGTR------------SAPGSTPMCIHDDG-GPPD-- ------------------------------------------------------------ -------------------------------VRPTPRPDVDPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQSGRIEHVPLESYEMRKEG AKAVLHLPE-RVIIGVAYDCVEKVVYWTDITSPAISKASIQ-GGEPTTVI-RTDLGSPEG ITVDHIGRTIFWTDSMKDRIEVASLDG-SRRRVIVDSDLINPRAIVADPVHGHLYWTDWN REAPKIETSYMDGSNRRVLVQ-NDLGLPNGLTYDFQSSLLCWADAGTHKMECMHPDR--G DRQSVMEGIQ----YPFGIT-SYGRKIFYTDWKRNAV-VAMDRHSG-RESDEFQPS-KQT KLYGITSAYSQCPPG--RNYCSVNNGGCT--HLCLAT---PNG-RSCKCPNNPAT----- -AACV------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERP------------ --------------------------AEY >XP_021151656.1 nidogen-1 isoform X1 [Columba livia] ------------------------------------------------------------ ----MSRSL-----GGKNMIMIII-------------PNLTLHCKLPN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------KVATNGIIAVNE--------PSSEEKYLGQ-FP VSFGAIAPFMADLDTT----------------DGRGNVYYR-EDSSSDVLQ------RAS DYIRSGFPET-------------------------------------------------- -TFDPSSVV-------------------------------IVTWKLVA-PYQAPGEDHGL EE--KRNTFQAVLASSDSSSYAIFLYPEDSLQFYSTYSKNN---------DEKIPAMVGF SQASTNYYFWEKPGS-YNVIANDEDSIRNLHKS-----------------SNAGKQGVWV FEIGSS------------SDSIVPAKIS--------DVL--------------------- --ESLEFD---EQDQE--------------MTSKPFMSDYGSTEIRQQYVTSSTDSTEDD QHHITYSVPQLAA----EDFQTLYQDVTETPPTE-SFYG---HQDFPTAKAP-------P RPFQVQQFPPQ-----QPQVIDV----------E-EFDETGI-VFRYHTDVQ----QTCA N-NRHQCSVH-AICTDYPNGFCCSCIAGYK--GNGRQCVAEGSPQRVNGKVKGRIFVGNN P-VPVTFENTDL-----------HSYVVMNQGRAYTAIS-TIPETL-------GYSLLPL ------ASIGGIIGW----MFAVEQQ-GYKNGFSVTGGEFTRQTEVTFLGNNEKLVI--- -------------KQRFSGIDEH------GHLTISTEIEGRIPEIPSGASVHIEPYTELY -HTSSSVITSSS----TREYTVTEPERDGVASTYTGAYQWRQTISFDE---C-------- -IHDDSHHA---ASATQQLSVDSVFVLYNRDEQILRYAMSN------SIGPISDGS---- ---------------------------ADINR-NPCYTGTHNCD-TNAICRPG------- ---------------------------------TGNRFLCECSIGFRG-------DG--- ----NVCY---------------------------------------------------- ------------------------DVDECSEQPALCG--NNAVCN-------NQPGTYRC ECVEGYQFA-ADGRTCVAV-----DYAINH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CQTG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------THNCDIPQRAQCVYTGGS-AYICTC-------LPGF SGDG-RACED----------VDE----------------C--QQGHCHPDAFCYNTP--G SFSCQCKA------GYRGDGFRCV------------------------------------ --------------------------------------------LG--EAEKTKCQRERE VALGS----------VGTFFPREI---------------------------RVSHF---- -----IPQ-----------------------------------CDEHGN---YLPTQCHS SS--------GYCWCVDRDGNEIDGTR------------SGPGVRPPCLSTAA-PPVV-- ------------------------------------------------------------ -------------------------------IGPSVRPDTVPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQSGKIEHVPLEGNNMKKNG AKALLHIPD-KVVIGVAYDCTDKMVYWTDISGPSISRASLH-GGEPTTII-KTDLGSPEG IAVDHLGRNIFWTDSQLDRIEVARLDG-RQRRILFDTGLVNPRAIVVDPMRGNLYWTDWN REAPKIETSYMDGTNRRILVK-DDLGLPNGLTFDPYSSMLCWVDAGTKRLECMNPNQ--L GRRKIVEGIQ----YPFSVT-SYGKNLYYTDWRRDAV-VAVDRTIS-IENDNFQPH-KRS RLYGITTAFAQCPGG--HNYCTVNNGGCT--HLCLAT---PGG-RSCRCPDNTVG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERN------------ ----------------------------- >XP_017897955.1 PREDICTED: nidogen-1 [Capra hircus] ------------------------------------------------------------ ----MLATVRRSGAAWTWALL------------------LQLLLAGPG------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPE---------HGD--LELEAGDDLVSPALE LST-----------ALHFFDRSDIDSV--------------------------------- ---------------------------YVTTNGIIAMSE--------PPAKETHPGP-FP PTFGAVAPFLADLDTT----------------DGLGKVYYR-EDLSPSVTQ------LAA ECVQRGFPEI-------------------------------------------------- -SFKPSSAV-------------------------------VVTWESVA-PYQGPSKDPTL EG--KRNTFQCILASSDSSTYAIFLYPEDGLQFYTAFSKKE---------ENQVPAVVAF SQGLTG-LIWKSDGA-YNIFANDRESVGNLAKS-----------------SNSGLQGIWV FEIGSP----------ATASGVIPADVN--------LEL--------------------- -DDEAEYD---DEDYD--------------SVTHLGLEDAVTTSF-----PYEAPRRGDS G---TYNTPSDLS-----------------PRRM-ATER---PLTPPTEKTR-------S FQLPGERFPQQ-----QPQVIDV----------D-EVEETGI-VFSYNTDSR----QTCT S-NRHQCSVH-AQCRDFATGFCCSCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGDS Q-VPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APIGGIIGW----MFAVEQD-GFKNGFSITGGEFTRQAEVTFVGHPDKLTI--- -------------KQQFSGIDEH------GHLTIDTELEGRVPQIAFGSSVHIEPYTELY -HYSRQVITSSS----TREYTVTEPEQHGTAPSHVHTYQWRQTITFQE---C-------- -VHDDSRLV---LPSTQQLSVDSVFVLYNQEERILRYALSN------SIGPVRDGS---- ---------------------------PDALQ-NPCYIGSHGCD-ANAACRPG------- ---------------------------------PGTQFTCECSIGFRG-------DG--- ----RTCY---------------------------------------------------- ------------------------DIDECSEQPSVCG--NHAVCN-------NHPGTFRC ECVEGYRFS-EAG-TCVADM---DLRPINH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHDCDIPQRAQCKFMGHG-SYTCIC-------LPGF SGDG-RACQD----------VNE----------------C--QPSRCHPDAFCYNTP--G SFVCRCKY------GYQGDGFHCV------------------------------------ --------------------------------------------PG--GVEKTRCQQERE RVV------------GTADSPRPQ---------------------------PPGLF---- -----VPE-----------------------------------CDEQGH---YVPTQCHS ST--------GYCWCVDRDGQEVEGTR------------TGSGMRPPCLSTVA-PPVH-- ------------------------------------------------------------ -------------------------------FGPPVLTAVIPPPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIERLPLEGSTMTKSE AKTLLHAPD-KVIIGLAFDCVDKMIYWTDISQPSIGRASLH-GGEPTTII-RQDLGSPEG IALDHLGRNIFWTDSQLDRIEVAKLDG-TQRRVLFETDLVNPRGIVTDSMRGNLYWTDWN RDNPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDAYSSQLCWVDAGTHRAECLNPGQ--P NIRKVLEGLQ----YPFAVT-SFGKNLYYTDWKTNSV-VAVDLAVS-KEMDSFHPH-KQT RLYGITSALSQCPEG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------EQK------------ ----------------------------- >XP_006258247.1 PREDICTED: nidogen-1 [Alligator mississippiensis] ------------------------------------------------------------ ----M---------GWGWGLL------------------ALLALAGPG------------ ------------------------------------------------------------ ---------------RCG----PPLLPFGSE---------GGD--AELEAGDDVTSPALE LSA-----------PLHFYGSA-VHSV--------------------------------- ---------------------------HVATNGIIGMNK--------PSKEEKYLGR-FP ISFGAIAPFMADLDTT----------------SGHGKVFYR-EDSSPDVLQ------LVV SYIRRGFPEV-------------------------------------------------- -TFDPISVV-------------------------------IVTWARVA-PYRTPSEDAVL ED--KRNTFQAVLASSDSSSYAVFLYPEDGLQFWSTHSKNA---------KEKIPATVGF SQASTNYLLWEKLGS-YNIVAHDEESIRSLYKS-----------------SNIGKPGVWV FEIGSS-------------SIILPAKVS--------SSP--------------------- --ESLEYNDY-EEYQE--------------VTLQPSVSYHNSAETGQQHVTYDVHRKGGD QQHISYGVPQSAT----EEDLKS-SVVTGIPPIESSLNR---QADFVTGKTP-------P DPFQVQRFYQQ-----EPQVIDV----------E-EFDETGI-VFRYNTDVQ----QTCA N-NRHQCSIH-AVCKDYSNGFCCSCIAGYK--GNGRQCVAEGSPQRVNGKVKGRIFVGNN P-VPVVFENTDL-----------HSYVVMNQGRAYTAIS-TIPETL-------GYSLLPL ------ASVGGIIGW----MFSVEQQ-GYKNGFSLTGGEFTRQAEVIFLGNNEKLVI--- -------------KQKFNGIDEH------GHLTISTEMEGRIPEISFGASVHIEPYTELY -HSSTSVITSSS----TREYTVTPPERDGSSSSYTAAYQWRQTISFDE---C-------- -IHDDSHHP---VSATQQLSVDSIFVLYNKDEQILRYAMSN------SIGPVSDGS---- ---------------------------ADINR-NPCYTNSHDCD-SNAVCRPG------- ---------------------------------TGNQFSCECSVGFQG-------DG--- ----RFCY---------------------------------------------------- ------------------------DVNECSEQPTVCG--SNAVCN-------NQPGTYRC ECVDGYQFS-ADGRSCVAI-----EHVINH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CLAG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------THNCDIPQRAQCTYVGGS-SFICSC-------LSGF SGDG-RACVD----------VDE----------------C--QQNRCHPDAFCYNTP--G SFRCQCKA------GYRGDGFQCV------------------------------------ --------------------------------------------LG--EVEKTKCQHERE LALGS----------HIPRGSRP-----------------------------VGDF---- -----IPQ-----------------------------------CDEYGN---YKPTQCHS SS--------GYCWCVDSYGNEIDGTR------------SGPGIRPPCLSTAA-PPVV-- ------------------------------------------------------------ -------------------------------IGPSVRPDSIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQSGKIEHVPLEGNNMKKTD AKALLYVPD-KVVIGVAYDCKDKMVYWTDISGPSISQVSLH-GGEPTAII-KTDLGSPEG IAIDHLGRNIFWTDSQLDRIEVARLDG-NQRRVLFDSDLVNPRAIVADAVKGNLYWTDWN RDAPKIETSYMDGTNRRILVK-DDLGLPNGLTFDIYSSMLCWADAGTKKLECMNLSQ--P GRRKVLEGIL----YPFSIT-SYGKNLYYTDWRRDAV-VAVDRTVS-KENDNFQPH-KRS RLYGITTALAQCPPG--HSYCEVNNGGCT--HLCLTT---PAG-RSCRCPDNTVG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------EQN------------ ----------------------------- >XP_015799438.1 PREDICTED: nidogen-1 [Nothobranchius furzeri] MSGHPRTPVTGLQRLGRREKTPPAVCSAPRPKKPLNSQRRAILGSASPCSSNSLLTPFIQ KESNMGWQN-------QGWLFSA----------------SLVVFWASV------------ ------------------------------------------------------------ -------------RSIRR----EEFFPFGPS---------AGD--QLLESGDDQ-TFRLT LSK-----------PVLFYDGS-FDSL--------------------------------- ---------------------------YINTNGFVATKE--------PLNESTYLGK-LP PEFGAMAPLHGDLDTS----------------DGVGKVYFR-QDNSPDVLR------QAA EHINRGFPEE-------------------------------------------------- DEVNPINTV-------------------------------VITWVDIA-SHKPQTRGDGA ER--KRNTFQLVIASLETASYAIVLYARNGIQFTSTLVE-----------DNGVVMHAGF SQGLVKGFFYSSQGNYYRTTTDDEASVRALAEE-----------------TNSGLRGVWV YGIGTS----------PQFRNVVPGVVT-------------------------------- -----------DLPAE--------------TVDTQQHTDGQVKYS-----PAA------- -------------------------------EQI-------------------------- -EINPLRYQPQ-----NPEVVVV----------E-DPEINVD-VFSYNLG-------SCA N-NRNKCSQF-ADCRDYASGFCCHCRPGYY--GNGLQCVAEGKPQRMNGKLRGKVFVENS P-SPVEFNGNDL-----------HSYVVVNDGRSYVAIS-DIPTSV-------GPSLMPL ------LALSNVIGW----VFALEQP-GFRNGFSIIGGEFTRQAEVTFQPGNEKLII--- -------------RQEFEGTDEL------DHLVVSTTMDGRVPAVPPGSTVQIDPYTDVY -QYDSNLITSSS----TRYYTVTNPD----GSVETRSYQCRETITFQS---C-------- -QHDESLRD---VT-TQMLKVDQIFVLYDVNNNLLRYAMSN------KIGDVNGGQ---- ---------------------------TE--E-NPCFTGRHGCD-TNAVCRPD------- ---------------------------------QGSQFTCQCASGFSG-------DG--- ----RRCY---------------------------------------------------- ------------------------DIDECTENQQICG--PNAICN-------NQPGTFRC ECEDGYQFG-SDGRTCIEV-----DRPVDH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CEDG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------THTCDIPDRAQCSYTGGS-SYICSC-------LPGF VGDG-RICQD----------IDE----------------C--QPGRCHQNAVCVNTQ--G SFLCQCLP------GYSGNGVYC------------------------------------- --------------------------------------------SS--ERTKTRCEAHRD NVLSTME--------AHPRGARP----------------------------PISQY---- -----IPE-----------------------------------CDENGN---YLPMQCHG ST--------GYCWCVDRNGLEISGTR------------SAPSSRPMCIDHNT-VTPT-- ------------------------------------------------------------ -------------------------------VGPWPRPDVIAPPPG-------------- ------------------------------------------------------------ -----------------------------------TNLLFAQSGRIEHIPLEGYDMKKHD AKAVLHLPE-KVIIGVAYDCVEKMVYWTEITSPSISKASML-GGEPTAVI-RTDLESPEG ITIDHLGRTMFWTDSMRDRIEVASLDG-SQRRVLIDTDLVNPRAVIADPVSGNLYWSDWN RDAPKIETSHMDGSNRRVLVK-DSLTLPNGLTYDSQSSLLCWADAGTHKMECMNPSR--G DRSTVLEGIR----YPFGMT-SFGKTIYYTDWQRDAV-VSVDRYAE-KETDEFQPQ-KRT RPYGIAAAYPQCLSG--QNYCSVNNGGCT--HLCLAT---PNG-RSCKCPDNAVA----- -VGCV------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ESG------------ ----------------------------Y >XP_020764015.1 nidogen-1 [Odocoileus virginianus texanus] ------------------------------------------------------------ ----MLATVRRSGAAWTRALL------------------LQLLLAGPG------------ ------------------------------------------------------------ -------------GCLSR----QELFPFGPE---------HGD--LELEAGDDLVSPALK LST-----------ALHFFDRSDIDSV--------------------------------- ---------------------------YVTTNGIIAMSE--------PPAKETHPGL-FP PTFGAVAPFLADLDTT----------------DGLGKVYYR-EDLSPSVTQ------LAA ECVQRGFPEV-------------------------------------------------- -SFKPSSVV-------------------------------VVTWESVA-PYQGPSKDPAL EG--KRNTFQSILASSDSSTYAIFLYPEDGLQFYTTFSKKE---------ENQVPAVVAF SQGLVG-LIWKSDGA-YNIFANDRESIGNLAKS-----------------SNSGQQGIWV FEIGSP----------ATASGVVPADVN--------LGL--------------------- -DDGAEYD---DEDYD--------------SVTHLGLEDVVATSF-----PHEAPRGGDG G---IYNTPSDLS-----------------PRRV-ATER---PLTPPTERTR-------S FQLPGERFPQQ-----QPQVIDV----------D-EVEETGI-VFSYNTDSR----QTCT N-NRHQCSVH-AQCRDFATGFCCHCVAGYT--GNGRQCVAEGSPQRVNGKVKGRIFVGAS Q-VPIVFENTDL-----------HSYVVMNHGRSYTAIS-TIPETV-------GYSLLPL ------APIGGIIGW----MFAVEQD-GFKNGFSITGGEFTRRAEVAFVGHPDKLII--- -------------KQQFSGIDEH------GHLTISTELEGRVPQVAFGSVVHIEPYTELY -HYSRQVITSSS----TREYTVTEPERDGTAPSHVHTYQWRQTITFQE---C-------- -VHDDSRPV---LPSTQQLSVDSVFVLYNQEERILRYALSN------SIGPVRDGS---- ---------------------------PDALQ-NPCYIGSHGCD-ANAACRPG------- ---------------------------------PGTQFTCECSIGFRG-------DG--- ----RTCY---------------------------------------------------- ------------------------DIDECSEQPSVCG--NHAICN-------NHPGTFRC ECVEGYRFS-EAG-TCVAVM---DQRPVNY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CETG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------LHDCDISQRAQCIYTGGS-SYTCSC-------LPGF SGDG-RACKD----------VDE----------------C--QPSRCHPDAFCYNTP--G SFTCQCKP------GYQGDGFHCV------------------------------------ --------------------------------------------PG--EVEKTRCQRERE HIL------------GAVDSQRPR---------------------------PPGLF---- -----VPE-----------------------------------CDDHGH---YAPMQCHG ST--------GYCWCVDRDGREVQGTR------------TRPGMRPPCLSTVA-PPVH-- ------------------------------------------------------------ -------------------------------HGPPVPTAVIPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQTGKIEHLPLEGSTMTKSE AKTLLHTPD-KVIIGLAFDCVDKMVYWTDISQPSIGRASLH-GGEPTTII-RQDLGSPEG IALDHLGRNIFWTDSHLDRIEVAKLDG-TQRRVLFETDLVNPRGIAADSVRGNLYWTDWN RDNPKIETSYMDGTNRRILVQ-DDLGLPNGLTFDAYSSQLCWVDAGTHRAECLKPGQ--P NRRTVLEGLQ----YPFGVT-SFGKNLYYTDWKTNSV-AAVDLAIS-KETDSFHPH-KQT RLYGITSALSQCPEG--HNYCSVNNGGCT--HLCLAT---PGS-RTCRCPDNTLG----- -VDCI------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------EQK------------ ----------------------------- >XP_030297897.1 nidogen-1 [Sparus aurata] ------------------------------------------------------------ ----MGWQE-------RGWLVCA----------------SFLGFVASV------------ ------------------------------------------------------------ -------------ESITR----GELFPFGPS---------ARD--RLMEAGNDQ-THRLQ LDN-----------PVLFYDGS-FDSI--------------------------------- ---------------------------FINTNGFVATAE--------PTSESTYLGK-MP PGFGMIAALQGDLDTR----------------DGEGRVYFR-QDSSRDALR------RSA EIINRAFPED-------------------------------------------------- DEFNPTHAV-------------------------------VITWVDVT-AHEPHSRGDG- NR--KRNTFQLVIASMETASYAIVLYPRDGIQFTSTPAN-----------GQSVVMHGGF SKGLVKGFLFSSQGPYYRTTTEDEASIRALAEE-----------------TNSGQRGVWV YEIGTS----------PYFTNVVAGEVT-------------------------------- -----------DLPAE--------------ATRRPAYTDGQQVEY-----PHF-ESE--- ------------------------------GAQI-------------------------- -EVHPVQYQPHQPG--NPEVVVV----------D-DTDINVD-VFSYNLG-------TCA N-NANKCSQF-ADCKDYSSGYCCHCRPGFY--GNGIQCVAEGKPQRMNGKVYGKVYVGNS P-SPVEFTSNDL-----------HSYVVVNDGRSYVAIS-EVPYTL-------GPSLQPL ------SALGGVIGW----AFALEQP-GFKNGFSIIGGEFTRQAEVTFLPGNEKLTI--- -------------RQEFKGIDEH------DHLAVSTTLEGRVPEVPRGSTVQIERYSEIY -QYSNNLITSSS----TRDYVVSLPD----GSTETRMYQWRQTITFQS---C-------- -QHGDSLRD---MKPTQMLSVDQVFVMYDANNELIRFAMSN------KIGDVNGGQ---- ---------------------------PQ--E-NPCFTGRHGCD-TNAVCRPG------- ---------------------------------EGTQFNCECAAGFNG-------DG--- ----RTCY---------------------------------------------------- ------------------------DIDECAENPQICG--FHAICN-------NQPGTFRC ECEDGYQFG-NDGHTCTEI-----DRVVDA------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CEEG-------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------THDCDIPERAQCSYTGGS-SFICSC-------LPGF FGDG-RVCKD----------IDE----------------C--QPGRCHQDAVCYNTQ--G SFTCQCRS------GYYGDGFYC------------------------------------- --------------------------------------------SA--ERTKTQCETHRD SLLG-----------AGPRGPRP----------------------------PIGQY---- -----VPT-----------------------------------CDENGA---YEPMQCHS ST--------GHCWCVDRNGQEIPGTR------------SGPGSRPMCINHGG-VPPP-- ------------------------------------------------------------ -------------------------------VGPTPRPDVHPLPPG-------------- ------------------------------------------------------------ -----------------------------------THLLFAQSGRIEHVPLEGHDMKKED AKAVLHLPE-KVIIGVAYDCVEKMVYWTEITSPSISKASIQ-GGEPTEVI-RSDLDSPEG IAVDHLGRTLFWTDSVKDRIEVASLDG-SQRRVIIDSDLVNPRAIITDPPNGNLYWTDWN RDAPKIETSYMDGSNRRVLVK-DDLGLPNGLTYDPQSSMLCWADAGTHKMECTHPAR--G DRRQVMEGIQ----YPFGIT-SFGKNIYYTDWRRDAV-VAVDRYAG-KESDQFQPQ-KRT KLYGITTAYAQCPSG--QNYCAVNNGGCT--HLCLAT---PAG-RSCKCPNNAVG----- -VGCV------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------ERD------------ --------------------------GGY
BMGE Cleaned alignment of selected proteins >sp|P14543|NID1_HUMAN Nidogen-1 OS=Homo sapiens OX=9606 GN=NID1 PE=1 SV=3 RAAWTLPLLLAGPVGCLSRQELFPFGPGLELEDGDDFVSPALELSALRFYDRSDIDAVYVTTNGIIATSEPPAKEFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSITQRAAECVHRGFPEISFQPSSAVVVTWESVAPYQGPSRDPDQKGKRNTFQAVLASSDSSSYAIFLYPEDGLQFHTFSKKEVPAVVAFSQGSVGFLWKSNGAYNIFANDRESVENLAKSSNSGQQGVWVFEIGSPGVVPADVIEDGAEYDDEDEDTRLGLEDVRGGADTYSVPSVLSPLGPPTERTRSFQLAVETFHQQHPQVIDVEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGSSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPVGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGIDEHGHLTIDTELEGRVPQIPFGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPYQWRQTITFQEVHDDSRPALPSTQQLSVDSVFVLYNEEKILRYALSNSIGPVREGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDIDECSEQSHTICNNHPGTFRCECVEGYQFSDEG-TCVAVVDQRPINYLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVEKTRCQHEREHILGAAGATDPQRPIPPGLFCDAHGHAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPCLSTVAQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLEGNMRKTEAKAFLHVPAKVIIGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAFSSQLCWVDAGTNRAECLNPSQSRRKALEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAKQTRLYGITTALSQCPQGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >tr|F1RAG3|F1RAG3_DANRE Nidogen 1a OS=Danio rerio OX=7955 GN=nid1a PE=1 SV=2 ----HILFGLTLSVSGITRHELFPFGRNQSLREGNDE-TQEVNLDPITFHDEQ-FSKIYINTNGFVALEKPTGESMPASFKMIAALQGDLDTSDGVGKVFFRQDFSTALLQQAADHINRAFPEDLVNPIHALVVTWLDVASHKAESRGDGLEHRRNTFQLVIASVETSSYAILLYPRDSIQFQT-----YTVHAGFSK--------TQELYRNTEDTEASVKDLPEQTNSGKRGVWVYEIGTFNIAPGEVP-------DLPLDRRSETQNQENLDGVYHHPEH--------------QVHTVQFTPQDPQVVEIDDNIQVDVFTYNSG---QCGG--QKCSKFAEC----SGRCCVCKPGYYGSGVHCVPEGVPQRMNGKVSGRVFVGNSPVPVDFASNDLHSYVVANDGRAYVAISAIPPVIGFSLQPLSSVGGVIGWAFALQQPGFKNGFSIIGGEFKRQADVSFQPGGEKLTISQEFRGIDEHDHLMVDTRLEGKIPEVPQGATVQIDSYSEIYQYSINLITSSSTREYVISLPD----GSYNFRETITFQGQFDE----VPSTQMLSVEQVFVMYDGAQLLRYAMSNKIGDVNGGQSE--ENACFTGRHGCDTNAVCKPGQGNQFTCECAAGFTGDIDECRETQNSICNNQPGTFRCECLDGFQFASDGQTCVEV--HRPVDPTHDCDVPERARCSYTGGSSYICTCAPGFMGDGRRCQDQVNQCHENAVCFNTPGSFSCQCNPGFHGDGFYC-EKTRCELHKESVVG--FGPHSARP-QPGRFCDAQGREPMQCHASIGQCWCVDRDGEEISGTRTGPGRFPVCRGHDEIRPTPNPNISPLPPGSHILFTQSGKIEYIPLDGHLKKNEAKTALHLPEKVVIGIAYDCVEKMIYWTDISTPAISRANLQGGEPVQLIKSDIGSPEGIAIDHLGRNMFWTDSMKDRIEVSSLDGTQRRVLVNTDLVNPRAILTDSTNGYIYWADWNRESPKIEMAYMDGTNRRVLAKDDLSLPNGLTYDPQTSLLCWADAGTHKVECMNPQQRRTQLMEEIQYPFGLTTDGKNFYYTDWTRVSVVVVDRHLRREVDEKRTRLYGITTAHARCPAGQNYCSSNNGGCTHLCLATRSCRCPDNAAE >NP_035047.2 nidogen-1 precursor [Mus musculus] WAMWTQLLLLVGPGGCLNRQELFPFGPGLELEAGDDVVSPSLELIELSFYDRTDITSVYVTTNGIIAMSEPPATEFPPSFGSVAPFLADLDTTDGLGNVYYREDLSPFIIQMAAEYVQRGFPEVSFQPTSVVVVTWESVAPYGGPSSSPAEEGKRNTFQAVLASSNSSSYAIFLYPEDGLQFFTFSKKDVPAVVGFSKGLVGFLWKSNGAYNIFANDRESIENLAKSSNAGHQGVWVFEIGSPGVVSADVNDDGADYEDEDYDSHLGLEDVRGYPDPHNVPRILSPRGVPTERTRSFQLPAERFPQHHPQVIDVEVEETGVVFSYNTGSQQTCANNRHQCSVHAECRDYATGFCCRCVANYTGNGRQCVAEGSPQRVNGKVKGRIFVGSSQVPVVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFLGHPGKLVLKQQFSGIDEHGHLTISTELEGRVPQIPYGASVHIEPYTELYHYSSSVITSSSTREYTVMEPDQDGAAPYQWRQTITFQEAHDDARPALPSTQQLSVDSVFVLYNEERILRYALSNSIGPVRDGSPDALQNPCYIGTHGCDSNAACRPGPGTQFTCECSIGFRGDIDECSEQNHAVCNNLPGTFRCECVEGYHFSDRG-TCVAAEDQRPINYLHNCDIPQRAQCIYMGGSSYTCSCLPGFSGDGRACRDQHSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCMSKTRCQLEREHILGAAGGADAQRPTLQGMFCDEYGHVPTQCHHSTGYCWCVDRDGRELEGSRTPPGMRPPCLSTVAQGPVVPTAVIPLPPGTHLLFAQTGKIERLPLERNMKKTEAKAFLHIPAKVIIGLAFDCVDKVVYWTDISEPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRTIFWTDSQLDRIEVAKMDGTQRRVLFDTGLVNPRGIVTDPVRGNLYWTDWNRDNPKIETSHMDGTNRRILAQDNLGLPNGLTFDAFSSQLCWVDAGTHRAECLNPAQGRRKVLEGLQYPFAVTSYGKNLYYTDWKTNSVIAMDLAISKEMDTKQTRLYGITIALSQCPQGHNYCSVNNGGCTHLCLPTRTCRCPDNTLG >XP_043332969.1 nidogen-1 isoform X1 [Cervus canadensis] GAAWTLQLLLAGPGGCLSRQELFPFGPELELEAGDDLVSPALELSALHFFDRSDIDSVYVTTNGIIAMSEPPAKEFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSVTQLAAECVQRGFPEVSFKPSSAVVVTWESVAPYQGPSKDPALEGKRNTFQSILASSDSSTYAIFLYPEDGLQFYTFSKKEVPAVVAFSQGLVGLIWKSDGAYNIFANDRESIGNLAKSSNSGQQGIWVFEIGSPGVVPADVNDDGAEYDDEDYDTRLGLEDVRGDSGTYNTPSDLSPLTPPTERTRSFQLPGERFPQQQPQVIDVEVEETGIVFSYNTDSRQTCATNRHQCSVHAQCRDFATGFCCRCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGASQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPDKLIVKQQFSGIDEHGHLTIDTELEGRVPQIAFGSTVHIEPYMELYHYSRRVITSSSTREYTVTEPERDGTSPYQWRQTITFQEVHDDSGPVLPSTQQLSVDSVFVLYNEERILRYALSNSIGPVRDGSPDALQNPCYIGSHGCDANAACRPGPGTRFSCECSVGFRGDIDECSEQNHAICNNHPGTFRCECVEGYRFSEAG-TCVAVMDQRPVNYLHDCDIPQRAQCIYTGGSSYTCSCLPGFSGDGRACKDQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFHCVEKTRCQLEREHIL---GAVDSQRPRPPGLFCDEHGHAPVQCHGSTGYCWCVDRDGREVQGTRTRPGMRPPCLSTVAHGPPVPTAVIPVPPGTHLLFAQTGKIEHLPLEGSMTKSEAKALLHAPDKVIIGLAFDCVDKMVYWTDISQPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSHLDRIEVAKLDGTQRRVLFETDLVNPRGIATDSVRGNLYWADWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCWVDAGTHRAECLKPGQNRRTVLEGLQYPFGVTSFGKNLYYTDWKTNSVVAVDLAISKETDSKQTRLYGITSALSQCPEGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >KAF4018772.1 hypothetical protein G4228_010616 [Cervus hanglu yarkandensis] GAAWTLQLLLAGPGGCLSRQELFPFGPELELEAGDDLVSPALELSALHFFDRSDIDSVYVTTNGIIAMSEPPAKEFPPTFGAVAPFLADLDTTDGLGKIYYREDLSPSVTQLAAECVQRGFPEVSFKPSSAVVVTWESVAPYQGPSKDPALEGKRNTFQSILASSDSSTYAIFLYPEDGLQFYTFSKKEVPAVVAFSQGLVGLIWKSDGAYNIFANDRESIGNLAKSSNSGQQGIWVFEIGSPGVVPADVNDDGAEYDDEDYDTRLGLEDVRGDSGTYNTPSDLSPLTPPTERTRSFQLPGERFPQQQPQVIDVEVEETGIVFSYNTDSRQTCATNRHQCSVHAQCRDFATGFCCRCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGASQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPDKLIVKQQFSGIDEHGHLTIDTELEGRVPQIAFGSTVHIEPYTELYHYSRRVITSSSTREYTVTEPERDGTAPYQWRQTITFQEVHDDSGPVLPSTQQLSVDSVFVLYNEERILRYALSNSIGPVRDGSPDALQNPCYIGSHGCDANAACRPGPGTRFSCECSVGFRGDIDECSEQNHAICNNHPGTFRCECVEGYRFSEAG-TCVAVMDQRPVNYLHDCDIPQRAQCIYTGGSSYTCSCLPGFSGDGRACKDQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFHCVEKTRCQLEREHIL---GAVDSQRPRPPGLFCDEHGHAPVQCHGSTGYCWCVDRDGREVQGTRTRPGMRPPCLSTVAHGPPVPTAVIPVPPGTHLLFAQTGKIEHLPLEGSMTKSEAKALLHAPDKVIIGLAFDCVDKMVYWTDISQPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSHLDRIEVAKLDGTQRRVLFETDLVNPRGIATDSVRGNLYWADWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCWVDAGTHRAECLKPGQNRHTVLEGLQYPFGVTSFGKNLYYTDWKTNSVVAVDLAISKETDSKQTRLYGITSALSQCPEGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >XP_018118629.1 nidogen-1 isoform X1 [Xenopus laevis] KGLFFLFCLLPNPGSFIKVDTFFPYGRDLLLTPGDDSDSEPLRPNSLHFYDGT-ISTLFVTTNGMIATSKPPPEDFPPDFGLIAPFLSDIDTSEG-GNVFYREDTSQDVLHLASKHINRGFPGSTFIPKSALVFTWEDVLPYYSQRGDAIPHNKGNTFQAVLASDESKSYAIFLYPEDGLNFHTQPKNNNSARVGFSKGAEAILWKTKGPHNEFANDYYSLEMLRWKTNSGMQGVWIYEIGGPSVVAANVEDEKEENHSEETE--------QDYENKPNIPGLNLQEDVILGNV---NFQVPSFPQNNPQIVIVELEDTGVVFQYNTGNQQTCANNRHQCSSQAFCKDYSTGFCCTCIPGYYGNGRQCVAEGSPQRVNGKVKGKIYVGSNPIPVVFEGIDLHSYVVVNDGRAYTAISTIADSLGYSLLPLASIGGVIGWMFSVQQPGYKNGFSITGGEFTRKTEVTFLHSNKKLVILQKFSGIDEHGHLTISTELDGSVPEIPYGSTVHIEPYTELYQTSSSVITSSSNREYTVEFPQ----DGYQWKQTITFTEVHDTAAPTVPAIQQLSVDRVFVLYNEEKILRYASSNSIGPITDSPVDTNRNPCYIGAHNCDTNAVCRPAQGNQYICECTSGFRGEIDECQEQDNAICNNQPGTFRCECNDGYQFLEDGRTCASV--ERTINHTHNCDIAERAHCIYTGGSSYICACLSGYSGDGRVCEDETSQCHPDAVCYNIPGSFSCHCKPGYQGNGFQCFQKTPCQLHQDSILGS-PSVRGARP--VGQFCDESGNVPRQCHSGSGYCWCVDKDGNELPGTRTRPGLSPPCLDIVTVGPVVRPDVAPLPPGTHLLFVQSGKIEHVPLEGNMKKSDAKTLLHIPDKVIIGVSYDCVDKTVYWTDITGPSISRASINGGEPTAIIKTELGSPEGIAVDHLGRNIFWTDSVLNTIEVAKLDGSNRRILFDTDLENPRGIVADALKGNLYWTDWNRVAPKIETSYMDGTNRRILVKDDLGLPNGLTIDAYSSMLCWVDAGTKRMECMNPSQARRKIVEGIQYPFGITSYGKNIFYTDWKRDSIVAIDRTISKENDNKRSRLYGITTAYSQCPQGQNYCAVNNGGCKHLCLATRSCLCPENSTG >XP_040188888.1 nidogen-2 [Rana temporaria] ----LWHCLLLGFSAAISRQELFPYGESRLLPDGDDETSEVVTLTPILFYEAD-FKELYVGTNGIISTQDFPRETFPTDFPVIAPFLSDIDTSNGKGKIYYRQDNSPDILSTVARQVDRGFPQAAFSPTNVFMVTWDNVGAYEEVTRHAEPSNKLNTFQAVLAYDDSDTYAIFLYPEHGLQFFTRPKESLPARVGFSRGDSE-MLKKEAPYS-VTSSEQSVKNLYQTSNVGVPGVWVFHIGSLNVIPAKVPENNYEDNDEDYPTEAPTTDSFIDAETLYTPNNPLSESRVLGNIPPSESVSEDFNNVDPQRSDVVGGLDTDVLTFNPVSRETCDRKPGYCSPYAFCTDYATGFCCHCQDSYYGNGVHCLPKGAPHRVNGKVSGNLLVGQR--PVTFDGIDMHAYIVVNDGRAYTAISQVPEPASWSLTPLTAIGGLFGWLFALEKPGHQNGFSITGAKFVHNLEAVFSPGEEVIHVTQTADGFDSDNYIHVRTTIKGKIPYIPETSTVQIAPYYEIYQHSGSVVTSTAYREYTVTSQS----GDYRLKQNITYQEGHAQKYP--PTAQKLSVDRVFAMHNDEKVLRFAITSHIGSLHDSSQEPTQNPCFDGTHQCDTRAQCQPATGLNYSCVCASGYRGDYDECEDQQNTRCVNLPGSFRCECVPGYVFSADGQNCILG--SSFGNPTHSCDLT-TSQCVPRGDGVFTCECFPGYTRSGQSCIDAERRCHPDATCANVPGSFSCRCNPGFTGDGFQCTPQTMCERWKQSLVDHY----GGSP-SAEHYCDAYGESPLQCHGNSGYCWCVDKDGREIEGSRTQPGMTPACLPSVAVRPTPRPDVTPPTSGTYLLYAQGQQIGYLPLDGVFRKDKARTLLALHGSIVVGIDYDCQEKKVYWTDVSGRTISRAGLEGAEPEVLISTDLMSPEGLAIDYLRKTMFWTDSGTDKIESARLDGTFRKTLFDTNLVNPRAITVDAVRGNLYWTDWNREAPKIETSYVDGSNRRILVNDNIGLPNGLTFDPFSKQICWADAGTKKLECILSDGGRRVIQSNLNYPFSVVGFANHFYHTDWRRDGVISINKENGQITEEQRSHLYGITAIYPYCPSGKK--------------------------- >OWK09497.1 NID2 [Cervus elaphus hippelaphus] ----------------------------------------------------------------------------------------------GATRV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PPQLVAI-------------------------------------------------------------------------------------------------------QV-------------------W---------------------------------------------------------------PTPASVHL---------------------------------------------------------------------------------------------------------------------------------DVDECATGPNSVCVNLLGSYRCECRSGYEFADDRHTCILI--TPPPDPRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTDSENRCHPSATCSNTPGSFSCRCQPGYYGDGFQCTPRTVCERWRESLLEHY----GGTP-RDDQYCEGLGHTPLQCHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAIRPTPRPDVTPPPVGTFLLYAQGQQIGHLPLNGTLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEGAEPETVINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGGRRVIQNNLNYPFNIVSYADHFYHTDWRRDGVIAVNRDTSQFTDEQRSHLYGITAVYPYCPGKQLLRQ-------RLGISRRSSS------- >XP_213954.4 nidogen-1 [Rattus norvegicus] WEMWTQLLLLAGPAGCLSRQELFPFGPGLELEAGDDVVSPSLELIELSFYDRSDITSVYVTTNGIIAMSEPPATEFPPSFGSVAPFLADLDTTDGLGNVYYREDLSPFIIQMAAEYVQRGFPEVSFQPTSVVVVTWESMAPYGGPSGSLVEEGKRNTFQAVLASSNSSSYAIFLYPDDGLQFFTFSKKDVPAVVGFSKGLEGFLWKSNGAYNIFANDRESIENLAKSSNAGHQGVWVFEIGSPGVVPADVNDDGADYEDEDYDSHLGLEDVRGYPDPHNVPRTLAPHGIPTERTKSFQLPVERFPQKHPQVIDVEVEETGVVFSYNTGSQQTCANNRHQCSVHAECRDYATGFCCRCVANYTGNGRQCVAEGSPQRVNGKVKGRIFVGNSQVPVVFENTDLHSYVVMNHGRSYTAISTIPESVGYSLLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFLGHPGKLILKQQFSGIDEHGHLTINTELEGRVPQIPYGASVHIEPYTELYHYSSSVITSSSTREYTVTEPDQDSAVPYQWRQTITFQEAHDDSRPALPSTQQLSVDSVFVLYNEERILRYALSNSIGPVRDGSPDALQNPCYIGTHGCDSNAACRPGPGTQFTCECSVGFRGDIDECSEQNHAICNNHPGTFRCECMEGYHFSDRG-ICVAAVDQRPINYLHNCDIPQRAQCIYMGGSSYTCSCLPGFSGDGRACQDQHSRCHPDAFCYNTPGSFRCQCKPGYQGDGFRCVGKTRCQLEREHILGAAGATDAQRPTLQGMFCDEYGHTPTQCHHSTGYCWCVDRDGQELEDTRTPPGMRPPCLSTVAQGPVVPTAVIPLPPGTHLLFAQTGKIERLPLERNMKKTEAKAFLHIPAKVIIGLAFDCVDKVVYWTDISEPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRTIFWTDSHLDRIEVAKMDGTQRRVLFDTGLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSHMDGTNRRILAQDNLGLPNGLTFDAFSSQLCWVDAGTHRAECLNPAQSRRKVLEGLQYPFAVTSYGKNLYYTDWKTNSVIAMDLAVSKEMDAKHTRLYGITIALSQCPQGHNYCSVNNGGCTHLCLPTRTCRCPDNTLG >XP_040524442.1 nidogen-1 isoform X1 [Gallus gallus] ---GTALLALALPL-ALPAELLLPHGAEAALEPGDDARSAALELGALHFYGAA-VRSLYVATNGIIAVNEPKNEEFPVSFGAIAPFMADLDTTDGRGNVYYREDSSSDVLQLASDYIKGGFPEAAFDPSSAVIVTWKLVAPYQGPGEDLTLEEKRNTFQAVLASSDSSSYAIFLYPEDGLQFYAYSKNDIPAMVGFSQASTNYFWENPGSYNVIANDEDSIRNLHKSSNAGRQGVWVFEIGSSTIVPAKVS-ASLEPSEEDQESKPFMSDYIEEDQTYSVPQLAVHREFPTAKAPPRQFPAQQFPPQGPQVIDVEFDETGIVFRYHTDVQQTCANNRHQCSVHAICKDYPNGFCCSCIAGYKGNGRQCVAEGSPQRVNGKVKGRVFVGNNPVPVTFENTDLHSYVVMNHGRAYTAISTIPEALGYSLLPLASIGGVIGWMFAVEQQGYKNGFSITGGEFTRQTEVTFLGNNEKLVIKQKFSGIDEHGHLTISTEMEGRVPEVPSGASVHIEPYTELYHASSSVITSSSTREYTVTEPERDGVASYQWRQTISFDEIHDDSLHAASATQQLSVDSIFVLYNDEQILRYAMSNSIGPISDGSADISRNPCYTGTHNCDTNAVCRAGTGNRFSCECSIGFRGDIDECSEQSNAVCNNQPGTYRCECVDGYQFAADGRTCVAV--EYAINHTHGCDIPQRAQCVYTGGSAYICTCLPGFSGDGRACEDQQGHCHPDAFCYNTPGSFSCQCKAGYRGDGFQCVVKTKCQHEKEVALGS-GGTFFQREIRVGQFCDEHGNVPTQCHGSTGYCWCVDRDGNEIDGTRSGPGVRPPCLSTAAIGPSVRPDTIPLPPGTHLLFAQSGKIEHVPLEGNMKKNGAKALLHIPDKVIIGVAYDCMDKMVYWTDISGPSISRASLHGGEPTTIIRTDLGSPEGIALDHLGRNIFWTDSQLDRIEVARLDGRQRRILFDTGLVNPRAIVVDPVRGNLYWTDWNREAPKIETSYMDGTNRRILVKDDLGLPNGLTFDPYSSMLCWVDAGTKRLECMNPNQGRRKIVEGIQYPFGVTSYGKNLYYTDWRRDAVVAVDRMISVENDNKRSRLYGITTAFAQCPGGHNYCTVNNGGCTHLCLATRSCRCPDNTVG >XP_001156001.1 nidogen-1 [Pan troglodytes] RAAWTLPLLLAGPVGCLSRQELFPFGPGLELEDGDDLVSPALELSALRFYDRSDIDSVYVTTNGIIATSEPPAKEFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSITQRAAECVHRGFPEISFQPSSAVVVTWESVAPYQGPSRDPDQKGKRNTFQAVLASSDSSSYAIFLYPEDGLQFHTFSKKEVPAVVAFSQGSVGFLWKSNGAYNIFANDRESIENLAKSSNSGQQGVWVFEIGSPGVVPADVIEDGAEYDDEDEDTRLGLEDVRGGADTYSVPSVLSPLGPPTERTRSFQLAVETFHQQQPQVIDVEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGSSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPVGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGIDEHGHLTIDTELEGRVPQIPFGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPYQWRQTITFQEVHDDSRPALPSTQQLSVDSVFVLYNEEKILRYALSNSIGPVREGSPDALQNPCYLGTHGCDTNAACRPGPRTQFTCECSIGFRGDIDECSEQSHTICNNHPGTFRCECVEGYQFSDEG-TCVAVVDQRPINYLHNCDIPQRARCIYTGGSSYTCSCLPGFSGDGQACQDQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVEKTRCQHEREHILGAAGAADPQRPIPPGLFCDAHGHAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPCLSTVAQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLEGNMRKTEAKAFLHVPAKVIIGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDVFSSQLCWVDAGTNRAECLNPSQSRRKALEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAKQTRLYGITTALSQCPRGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >XP_791550.3 nidogen-1 [Strongylocentrotus purpuratus] ----MIFAVLIAVVNCLPRDQFFPFGEGKKLNRR-SKKPLTLSFRPFTFLGEE-QSLLYIVRDGYVSFSSGARGS-------IAPFHTKLKLIRGQSSVWYRTTVSSNEEDEIINLIQRNFRSRTFSPSSFVIVTWENMAVRNSDHEVI----GTVTFQLILVADAMHSFAFFLYDEN-----DYPRPDSNIDAGFTSGKAHNQWEFE-MYTTEDNKAATLFEAMRDSNVGMNGMWAYKIDGRNIIPAVAY-ESLPQNEPPQD--------------------------------------------AVNIQL-N------TFDVVLDFENQC--TRETCSVDGRCVPYPTGHCCACNEGFMGNGIHCLSINDNGRMNGRVNGTINGVTIP-----DEVYLHTFIMGGGGRTFTAISPVPSSIAYSMQILLPIGELMGWMFAEPAAKGINGFMQTGGDLLYSANIRF-ENGDEVSIIQRYTGVDESGVIGGYVTIDGNVPNLSPGTSVSVDRHSEVYKYRPGYVYSSEQRSLD---------ADFSIEQTITYQEEADDINTDSLTAMRMNTTYAYSIFEQGDILRYAMITNVGPDIGVP-----DACQDNN--CGTNAECFP-QANTFTCRCRAGYTGESPSDPCDRNANCYPAGNSYTCQCNTGFN--GDGRVCVADQASDPCDTNNNCSP--YAYCRPRGDTDFTCECAPGYVGDGYNCEELNNRCHPYADCSPVPGGYTCSCRSGYQGDGYLCELCSDCGRDADCL----PEGRGYRCICRAGFCLEGADANARCQNNRGSYTCRCNAGYRGDGFT--------C------------EALPEADG-SLVFGQGMSVMNLPRDGS-----GNKVYMKSRQTVVGLGYDCRHEYVYWTDISGRAIMKASLDGRDVSVVVNTSLSSPEGVAVDHLSRNLYWTDSGFDRIEVANLDGTNRHVLFDTDLVNPRAIVIDPVGGYLYWVDWDRSYPRIEVSGMDGSGRAVFLDEDLIMPNGLTIDLVSQLLCWADAGTQKVECMNLDGSRYPVYRPAQYPFGLASLGNNLYWTDWQTSNIQFINKNGGEVQSLGNGRTYGIAAV-TQCTDGNNRCAYENGGCRNLCLPAATCVCPNALAP >NP_001256467.1 NIDogen (basement membrane protein) [Caenorhabditis elegans] ----KLLFLYLLIETTTANPAFYPYGQPNRLDY--SMEQSAIALKPLTYMEQS-VDELFLSHNGIVGLGKPTPE-MTISTPAIAVFYVPV----TSGVIDYRSSDDQGLLTKLTQDVKQVFADAEFHGLQAVIITWTQIE--NAEKD------GPASFQLAIVSDGISTYAIFRYES--LPWS------YYAQAGFVR--------SIGKQTNVNSGGPDVKELVNLSNNQFGNFFIFRVSGSPKDEGADD---YDYNDQEYEPKDKFVDNERGCECAERPHAPREDDE------DEQVDGTRYE--EPARQAQQPQQQPQRSQEGSLPKMSCSQDDKSCHANSVCQDFEGGFCCNCDTGFYGNGKECLPKGEPQRISGSFEGVINR------IPIDKTELHTFATSTDGNVHTAVSKIPSDLGHPLRFLYSIGGVMGWLFADVQSNVYNGFQLTGGLFNRTVALHI-EQNYYVTIKQEFSGRNIHDYFKSHLFVSGTLPDIAPGSEVIFPDYEEEYRERRGYLTSKAAFDVIVRDG-----GNMSVDQQITFEEPNKEFDRD---SMKLHVKRINVVYNDEGVVRYGAKNSVGPAVSAPESISTSVCAPGRHQCTPNMKCRV-VDPSYRCECEPGYQADLDECQRGQHAKCTNRPGSFSCQCLQGYQ--GDGRSCIRE--HQASHHHNQCHQ--WGECVFTSEHTGRCKCRGWYVGDGNHCGPGSYVCDVNAECMPEPGGSECVCKAGFSGNGVTCEHSSHNRHEQQQQTGSL--------------CSEHGS--CAYHHSLGYYQCACTEPYVGNGVE--------C-----TLPGSSASAESSTRSDKLLVARGMAIFERSTNPD----YGKQLIVIPHHIPVGIDFDCKEEKIVWSDMSGHSIRTSSLNGTEHKSYFNKELSSPEGIAVDWSSRNVYYADSMNDEIGVASLNGKFKKSLVTEGLVNPRSVVLDLYGRHLYYSDWHRENPYIGRVDMDGKNNRVFLNEDVHLPNGLTILPNRRELCWVDAGNHRLSCIQYNGGRRTVFSSLQYPFGLTDEEQKFYWTDWKDNRIHSVGVYGEGYRSFGSGKVFGILAVPKSCVGPSTPCSEDNGGCQHLCLPGAVCECPDNVKV >XP_038046995.1 fibropellin-1-like isoform X27 [Patiria miniata] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAWLFALPSGKGYNGFMLTGGKFRQTLNITF-STGEQMLITQDFQGVDENGYIRVIADWNGNIPEITPSDYVFVDDHKEEYRHRLGVIHTFAKRSLQV---------NYTMDQTIEYDESADEADTEILNFMRVSMTETYLIYESEEILRFSMIGKVTPASEQI-----DPCVSNN--CDRNAQCLPAQADRYTCACNAGYQGESDHCA--PNARCVSAVFGYQCFCDPGYR--GDGYTCQANNATDPCANNNNCDV--NARCVPSQSG-YQCYCNQGFNGDGFTCQAYNNRCDFNAECSPAQGGYSCTCNQGYEGDGFTCRLCSACDASAQCI----PEGRGFRCVCRSGFCSQSGARYATCYNVRGSFSCYCQPGYEGDGFS--------C----------QEVTQPELDDGALIYARGMAVMRVPLNAN----PGNKIVFRSGQTIVGLGYDCQEEYIYWTDVSGRTISRAKADGSSTEVLISRGLSSPEGVAVDWLSRNMYWTDSGYDRIEVANLDGSNRRVLLKTDMINPRAIAVDPIGGLMYWTDWNRDAPKIERANMDGSERSVLVDSNLGLPNGLSLDYTTSQICWTDAGTKRIECMNMNGTRFTVLPNSNYPFSIASYGFKLYWSDWETKSIQTISKTGGESTDLGNGRIYSVTAI-TSCPSTSNACSSNNGGCSSLCLPTRYCACPTNLEG >XP_031557799.1 nidogen-like [Actinia tenebrosa] ----RLLVLLVIQSSCLVLQEFYPDGIDELLA---RRISPPVTLGTYNLYGKP-YTSLRVYKNGLITLGEPQKHRFPPEAKVIAPFYGQGDFT-NTSRISYGETRDSDILTRASKDVKQSFSGEEFNASAVFIVTWCQVKAQHSQHK------KNNTFQAVLVTNGDQTFVIFNYLTRGLQWAGYHSQWAYAQVGFSAGDFV-------RSTLPGSGTNQVHWLASKSNMNTPGRWIYKVGWPNEVQSADSDDSTNTDAQFYDWKDVSIRSHNGSQLNDIRHLIKNDDEVC----GGQMTASVYQ--SVGLAAV---------QSGGQRKDECAVGVVSCHANATCINKSPGYCCQCNEGFYGNGITCIEIGAVQRMVGFLSGTVNG------EEFISLNMDTIAFSDDGRAYVSVRAFPPYLAHSARVLTPLTDVVGWMYAKPKPGFYNGYNVVGARFVRRASLRF-DSGEELAILQKYQGRDVLHYMKVETTMNGAIPRIHPKAEVRMRKFRQEFRTAAGRVQSRGTVKYQV---------DFTVDQFIDYDEEADVLTSNAQAFLGIAVKGTFINTTDSIDVQSQEADKVTCHTRGVTYCDDDECKLGRYRCAPDADCVNTIALGLLCNCNPDYQGDENECELKTNADCINTVGSYSCRCRLGYQ--GDGLSCQKA--SASCGGGVTCDA--KARCVQTPQGTRQCVCNTGWQKNGNRCIDQTNPCHPNADCINSIGSFSCRCKPGYNGNGQACNGQSRCPANTDCINREGFVSNGSSCICNAGWCEDDGTGGVQCHPDAEGTRCVCKPGYLGDGRKDECHEHATC--TNSVGDGKQCESDGTCEGASLIYTKGNSVQRMSLPPR---NAIGLVYNHEGMVNVGLDYDCVEEYIYWTEVMEGCIMRAKYDGTNRELVFRSEVRSPEGLSVDWIGRNLYWTDSGLDVIEVSRLNGSNRKVLISNGLYDPRAILVDPPSGKMYWSDWTRRRPRIETADMDGTNRRVLVYDDLGLPNGLTLVQTTNELCYTDAGSWSIRCVDLAGNVRKVLTRVTYPFGIAYFNRTLYWTDWNQNLIHRIGVESSPDSSLKTGKIFDVKAV-QPCPAKRNPCSDKNGGCLGLCLLKYTCSCPKGQFP >XP_039259166.1 nidogen-like [Styela clava] ----MVLLAVFAVGQSAVFNDFYPFDREHRVPKGDNTSSPQFELDPIIFYDSV-YNGIKVNADGFVTLGVVEHEIEHLLEPVLVPFGFNLNNT-DASEIYYQEHKDEATLSRATNDIQKAFVETAFVAKSAFIVTWVRLESPEHPG-------LTFTFQCVVVSNHLSSFAIFLYADDELAAGSEEI--LIAKAGFSDKGGD------------QLESMTATELLEGGNAWSTGEWIFQIGGVEEIPSHHLAEPIHHRESGFE--------------------------------------------VPEVNFN----------YGSD-QQDC--DSLECDPESTCTAFADGYCCQCSEGSFGNGYACIREDDDVRYNGQVDGYSIVMSDPSNETAKGVDMHSYVVTKDGRAFSVMNEISAKLYRALQPMAIFGTTLGWLFAQAEAPAINGFQYSGGKIVSETYIRYTTGQYEFRIRQEYDQVINDKVLNGRMTFSGRLPPVEEGENINVDDYTQIYRTGADSIRSRDTRRYIVGDT-------FTVDQSIRFEGEASFEE--VPADLAVDVSEVFLKFFDENNLRFAVNSRIRPAEEVGVRPVEPSIIPDTPVPDTPVPDTPEPATQTVCERQLQQVQDVGTFA--YNSICWEEIHGTRTEPLVGYQLDSDVRAPPPA--QTP---RSNAETD---------------RIVAGSEANS-----ESGAYEP---VQQLPGSFMCV---DFDGEEISRSCLTPCQLAAYVAESSN---------ETNEFCKADGDNPEQCVE--TYCYCVDENGLEITNSRLDCGKFNSKPVTSTTTPTTTTGPIVGQEVRRLLFAQTMGINVIDLPVT-ENSVSRRLFARSDQITIALGYDCSSKKYYWTDVSKRRIYSSVLDDGSRAQFLGDRLRSPEGISVDFLSGNVYWTDSEYDRIEVASADGSNRMTVVSGDIVNPRGIAVDPIRGRMYWTDWNRKAPKVWVANMDGSDRRVLLSEGLGLPNDITIDFYRQRVCFVDAGTFKVECMSLNGGRETIYQMKQHPFGLAVDGDVLYYSSWGGSKVHAVNWRTGDSIAIAHGQMYGVEIAHSQCPRGYNYCSSNNGGCSHLCLPTRECVCPPGAQD >ACK77669.1 RE69505p [Drosophila melanogaster] ----SLLSSVILVSDSLRASELYEFEDGHLLPKG-DSETIVLQLEPIHFYGEQ-YEQLYINTNGILTFNSEFPE-FPLEYASIAAFYSNVDTSDEGTSISLFESKEQSILDRASSLVRYAFSSQEFEARQVIVATWRNVGYFDSKTD------RLNTFQVALIANEQSTFVQFIYPDGGLNWLGETAGLIRAQAGFVA--------EDGRYTLNGSGSENARFLSESTNLGVPGVWLFEVAPINVRSPDNA-------ESLTE--------------------------------------------SPALAL------------------SCQAHAHQCHEKAECHDKAEGYCCVCGSGFYGNGKSCLANDQPIRVTGTLTGELNK----QPVS-EEAKLQSYVVTSEGRTYTTINPLTPELGAQLRLVLPLLTTVPWLFAKSVGGVANGYQLTGGVYTHVSRLQF-DSGENLHVNQTFEGLNYWDQLSVKIEIYGEVPAVAADAVLILPDYVEEYFERPGELKSVQVLNINITE-------ELQVEQRILYRSLRDDEADPSATKVLQKISKVALDYVRDQALRIGAMSKVGVTPES------NACNDGTADCVENSVCVP-YEDTYRCDCYHGFAADIDECATGENAVCDNTEGGFNCYCTEGFE--GNGYRCLSN--STADNIDENCHI--NATCNWYGQERHICTCQPGFRGDGYNCDPRPDICDVHADCVYEEGKSECQCQAGYTGNGFNCQLAAECQSAEHCGENAF---DDGVCRCQADFCVPAGRGSVFCGSNAGVQYCDCLDGYQGDALTNNCGIHATCEPTEDFGNGSLCQERQHQDSDFLIVSQGVMIARVPLNGRVRP-------ISVAQMAIGLDKDCVEGRVYWGDISTKKIVSTKYDGTDLRPFITTDIESPEGIAIDVISRRLYWADSAKDTIEVASLDDSLRAVIINKQLVNPRGIAVDPYREKLFWSDWDRESPKIEMSNLDGTGRELLLGDDVTLPNSLVVLENSGEVCYADAGTKKVECIEPQNQIRTISNELSYPFGITFTHDQFYWTDWTTKKVEIVDSLGARQTPIGSHKMYGMTVVEQHCPQYQSPCQISNGGCTRLCLVNKSCKCTSASTG >KAG9432604.1 nidogen-2 [Apis mellifera carnica] ----CLVLATLVIAVALNKNDLYPYSIPQTDPNG-LLLSAETILKPIAFYDQI-FNSIFVNGNGVLSFARAMHR-FPLDDPVIAPLYTHVDTR-GSGRVYYGETDAPEILARAGGMVRSAFTDADFVPTHAFLATWVDVGYYNGKSD------KVNTYQVAISSNGTHSYVELLYPDDGIQWIGESHPNAKAQAGLMS---------EGRYTLRGSGTDQIQNVDKWSNVNRPGQWVFQVGPIDIKVPDNV-------EDSSA--------------------------------------------TNEVA-------------------NCRTGATACHSKATCVDYEVGFCCHCKQGFFGNGKSCQPNDVPLRVNGRISGTING------VEFLARDLQCYVQTKDGRTYTALSRVPEEIGASFQLLGNLGGVIGWLFAKPIGETKNGYELTGGLFNHTAELTFPSTGDKVTIRSNYLGLDVFGQLKMQAQIEGTLPQLGRDTGLDYGDYDELYRVQTGVIRSRAERVCKLAEG-----VEFVQDETIYYNEPYLTVEPE--DTTRLKFFRGVTTYETEGIIRFAVNTKVAPLEEE------DPCIQGRETCGDHSYCVV-DGDSFKCVCNPGYQYDVNECTAGPDAQCINQEGSHTCQCRPGFS--GDGRTCDKLPDTRCDNYMNRCHP--YAQCIYVTSTDYECRCNQGYEGDGMECIKEVDICDPNASCQQEESLAKCVCNPGFEGDGTMCSPIDECSSSSYCLENERSASSRYECTCNPGYCVVSDCNPSQCHVNAGGYRCVCAEGYNGDGIRNNCGRNAVCGYNQTVGDGTNCKSRPKHEANFLLVNQGMATLRIPFAPT--EDPGSPIYIAYMQMAIAIDIDCMNGKAYSSDISGNRIIELTYNGSMAETFL-PKVSNPEGLAIDWVSRNIFWT--GKTTVEVANLETKKRKVLVSDGLVNPRGIAVHPYRGKIFWSDWNRASPKLEWANEDGTDRAIFLQDYVKLPNSLSIDWAMDELCWADAGTFTISCMEIDSKINVVANQLTYPFGLAISQQHYYWTDWKTHKIEVAMKSTGRKQAIGSGKLYGIVVVPESCPRVTNACQFEGGRCSQLCLPNRSCVCADDADG >CAE1252257.1 LRP4 [Sepia pharaonis] -PPNKIVTIIIAFGDCMTKDEEFRCDNGDDCKDGSDEHCDQEECSPKAWICDEEVDCLFRCENGACINGTDCHEKFDCPLPSCSPRKFQCHTGDGSDEANCDENCSSGQFQIGSNKVCNGLSECDFNECEMVKATGGEVNIFANRIEIRKGNPSKSEFSFILDNLDNAIALDFHY-DLGLLFWDVSLDVTIVECGLKNTGGLVDWIHDKLWTDSGTSRIEVTELDGAAHPGKGMIFWTDWGSSTIVNSSLIDYAAGKLDAKYHIECAYLDG-----SHGLPHPFAFEDELYWTDWRSIWRANKFT--GNRVERV-------IHTYHPLRQNRCGSDNGGCS--HLCLPTKRNYICACPTGLAKDGKTCRD-----RLDNFLLFSTKSDLRR--ISFDTAEMNVVAVEWDSDTNTILWDVSTDTGSQAEVLSPAGLAVDWIYWTDQGTNVIEVANSDGLFRKVLIWENLDKPRDIVLKIERAGMDGN----GRTVLVSSNLTLPNGLSVDVKSSRLYWDAGTQTIESATYRRIVIGVG-----LPIVYEDSIFWTD-----------WNTKSVQMASKFNGNHQTLKKGLDNDITVFHRGRPYLS-TPCRKGNGGCSHLCLLAP-GPKTHTCACPTGILIDVDYFADVKNAVALQGMIYWSDTVVDKIQRSLDGSQVEDVI-SHGLDTWQNLDSP-RAIVLHYEAGMYWTDWRADMDGNNLTVIAWNDATTEVIECSDLNGNFRKVLVSGLTVAGRYIFWRTRSIHRADKITGEDTVIRSNIPGLRAVYCGQSNGCSHLCLPNPQGYSCVCPTGLLL------------------TQDGKTCQSMPS---VYLLFASRGSIRRISLDSH----YTDVYIPLPDHNAVALDFDIQESKIYYTDVTLDVIRRASLNGSNMEEVIHKGLSTTDGLAVDWVARNIYWTDTGRDVIEVARIDGTSRRTLVSENLDEPRAVAVFPKKGFMFWTDWGK-SPKIERAYLDGTSRKAIVTNDLGYPNGLSIDYVTKHLYWVDAQLDKIEMSDLNGNRIEIIRDVPHPFGLSVFGDYIYWTDWRTKSIHRANKMTG--LNRNMEGLMAISVVSPLRQTGTNQCAIRNGGCTHLCLARYKCACPTYPDS >XP_546076.2 nidogen-1 [Canis lupus familiaris] ETAWTLQLLLVGPGGCLSRQELFPFGPGLQLEPGDDRVSPALELRALRFFDKSDIDSVYVTTNGIIAMSEPPAKEFPPTFGVVAPFLADLDTTDGLGKVYYREDLSPSVTQLAAECVQRGFPEVSFQPSSVVVVTWESVAPYQGPSKDPEQEGKRNTFQAVLASSDYSSYAIFLYPEDGLQFYTFSKKDVPAVVAFSQGIQGLFWKSEGAYNIFANDRESIGNLAKSSNSGQQGVWVFEIGSPGVVPSDVSDDGAEYDDEDYETHLGLGDVRGDPGTYSAPRVLSHPGPPTERTRSFQPPAETFPQQHAQVIDVEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDFATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGNSPVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGIIGWMFAVEQDAFKNGFSITGGEFTRQAEVTFVGYPGKLVIKQQFSGIDEHGHLTINTELEGHVPHIPFGSSVHIEPYTELYHYSRGVITSSSTREYTVTEPEQGGAASYQWRQTITFQEAHDTSRPVLPSTQQLSVDSVFVLYNEERILRYALSNSIGPVRDGSPDALQNPCYIGTHGCDTNAACRPGPGVQFTCECSIGFRGDIDECSEQSHAICNNHPGTFRCECVEGYQFSEEG-TCVATVDQRPINYLHDCDIPQRAQCIYMGGSSYTCSCLPGFSGDGRACQDQPSRCHPDAFCYNTPGSFTCQCKPGYHGDGFHCVEKTRCQLEREHILRAAGLTDPQQPVMPGLFCDEHGHTPTQCHGSTGHCWCVDRDGRELEGTRTRPGMTPPCLSTVAHGPSVPTAVIPLPPGTHLLFAQTGKIEHLPLEGSMQKTEAKTLLHAPDKVIIGLAFDCVDKMVYWTDISEPSIGRASMHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSHLDRIEVAKLDGTQRRVLFETDLVNPRGIITDSVRGNLYWTDWNRDSPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCWVDAGTNRVECLKPDEGRRRVLEGLQYPFAVTSYGKNLYYTDWKTNSVVAVDLAISKETDAKQTRLYGVTTALSQCPQGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >NP_001094625.1 nidogen-1 precursor [Bos taurus] GAAWTLQLLLAGPGGCLSRQELFPFGPELELEAGDDLVSPALELSALHFFDRSDIDSVYVTTNGIIAMSEPPAKEFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSVTQLAAECVQRGFPEVSFKPSSAVVVTWESVAPYQGPSKDPTLEGKRNTFQSILASSDSSTYAIFLYPEDGLQFYTFSKKEVPAVVAFSQGLVGLIWKSDGAYNIFANDKESIGNLAKSSNSGLQGIWVFEIGSPGVVPADVNDDGTEYDDEDYDTRVGLEDARGDSGTYNTPSDLSPLTPPTEKTRSFQLPGERFPQQQPQVIDVEVEETEIVFRYNTDSRQTCANNRHQCSVHAECRDFATGFCCRCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGDSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHRDKLIIKQQFSGIDEHGHLTIDTELEGRVPQIAFGSSVHIEPYTELYHYSRQVITSFSTREYTVTEPERHGTAPYRWRQTITFRELHDDSRPALPSTQQLSVDSVFVLYNEERILRYALSNSIGPVRDGSPDALQNPCYIGSHGCDSNAACRPGPGTQFTCECSIGFRGDIDECSEQNHAICNNHPGTFRCECVEGYQFSEAG-TCVAAVGLRPVNHLHDCDIPQRARCIYMGGSSYTCSCLPGFSGDGRACQDQPSRCHPDAFCYNTPGSFTCRCKSGYQGDGFHCVEKTRCQHEREHIL---GTADSSRPRPPGLFCDEHGQVPTQCHSSTGYCWCVDRDGREVQGTRTRSGMRPPCLSTVAYGPPVPTTVIPLPPGTHLLFAQTGKIERLPLEGSMTKSEAKTLLHAPGKVIIGLAFDCVDKMVYWTDISQPSIGRASLHGGEPATIVRQDLGSPEGIALDHLGRNIFWTDSQLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCWVDAGAHRAECLKPGQSRRKVLEGLQYPFAVTSFGKNLYYTDWKTNSVVAVDLAVSKETDSKQTRLYGITSALSQCPEGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >XP_017203089.1 PREDICTED: nidogen-1 [Oryctolagus cuniculus] RAAWMLQLLLAGPGGCLSRQELFPFGPGLELEDGDDLVSPALELSALHFYDRSDIDSVYVTTNGIIAMSEPLAKEFPPGFGVVTPFLVDLDTTDGLRKVYYREDLSPSIMQLAAECVQRGFPEVSFQPSSVVVVTWESVAAYQGPNQDPIQEGKVST------------------------------------------------------------------------------------CPS-------------------THCALCSF------------------------------------YACVIDKET-QSRILFS---KAVEICFSDD-----QTECRDYATGFCCSCVAGYTGNGKQCVAEGSPQRVNGKVKGRIFVGTSQVPVVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGYPGKLVIKQQFSGIDEHGHLTIDTELEGRVPQIPFGSSVHIEPYTELYHYSSSVITSSSTREYTVTEPERDGTAPYQWRQTITFQEVHDDSRPALASTQQLSVDSVFVLYNEEQILRYALSNSIGPVRDGSPDALQNPCYIGTHGCDTNAACRPGPGTQFTCECSIGFRGDIDECVEQSHALCNNHPGTFRCECVEGYRFSDQG-TCVAIMDQRPINYLHDCDIPQRAQCVYTGGSSYTCSCLPGFSGDGRACQDQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCIEKTRCQLEREHILGAAGAADAQRPRPPGLFCDEHGHSPTQCHGSTGYCWCVDRDGREVEGTRTRPGMRPPCLSTVAQRPLVPTAVIPLPPGTHLLFAQTGKIENVPLDGNMKKTEAKALLHMPDKVIIGLAFDCVDKMVYWTDISEPSIGRASLHGGEPSTIIRQDLGSPEGIAVDHLGRNIFWTDSQLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAFSSQLCWVDAGTNRAECLHPSQSRRKVLEGLQYPFAVTSYGKNLYYTDWKTNSVVAVDLAVSKETDSKQTRLYGITTALSQCPQGHNYCSVNNGGCTHLCLATRTCRCPDNTMG >XP_024106979.1 nidogen-1 [Pongo abelii] RAAWTLPLLLAGPVGCLSRQELFPFGPELELEDGDDLVSPALELSALRFYDRSDIDSVYVTTNGIIATSEPPAKEFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSITQRAAECVHRGFPEISFQPSSAVVVTWESMAPYQGPSRDPDQEGKRNTFQAVLASSDSSSYAIFLYPEDGLQFHTFSKKEVPAVVAFSQGSVGFLWKSNGAYNIFANDRESIENLAKSSNSGQQGVWVFEIGSPGVVPADVIEDGAEYDDEDEDTRLGLEDVRGGADTYSVPSILSPLGPPTERTRSFQLAVETFHQQHPQVIDVEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGSSQIPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPVGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGIDEHGHLTIDTELEGRVPQIPFGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPYQWRQTITFQEVHDDSRPALPSTQQLSVDSVFVLYNEERILRYALSNSIGPVREGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDIDECSEQSHAICNNHPGTFRCECVEGYQFSDEG-TCVAVVDQRPINYLHNCDIPQRARCIYTGGSSYTCSCLPGFSGDGQACQDQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVEKTRCQHEREHILGAAGAADPQRPIPPGLFCDAHGHAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPCLSTVAQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLEGNMRKTEAKAFLHVPAKVVIGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDVFSSQLCWVDAGTNRAECLNPSQSRRKVLEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAVSRETDAKQTRLYGITTALSQCPQGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >XP_020929417.1 nidogen-1 isoform X1 [Sus scrofa] QAAWTLQLLLAGPGGCLSHQELFPFGPGLELEAGDDLVSPALELSALRFFDKSNIHSIYVTTNGLIATSEPPAKEFPPTFGAVAPFLADLDTTDGLGKVYYREDVSPSTTQLAMECVQRGFPEVTFKPSSVVVVTWENVAPYQGPGKDPAQEDKRNTFQAVLASSDASSYAIFLYPEDGLQFYTFSKKDVPAVVAFSQGVVGLIWKSDGAYNIFANDRESLGNLAKSSNSGQQGVWVFEIGSPGVVPSDVNDDGTEYDDEDYDTGVGLEVVRGDAGTYNMPSDLAPPTPPTERTRSFQLPAETFPQQQPQVIDVEVEETGVVFSYNTDNRQTCANNRHQCSVHAECRDFATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGNSPAPIVFENTDLHSYVVMNHGRSYTAISTIPETIGYSLLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPDKLVIKQQFSGIDEHGHLTIDTELEGRVPHIPFGSSVHIEPYTELYHYSRQVITSSSTREYTVMEPEQDSTAPYQWRQTITFQEVHDDSRPALPSTQQLSVDSVFVLYNEERILRYALSNSIGPVRDGSPDALQNPCYIGTHGCDTNAACRPGPGTQFTCECSIGFRGDINECSEQSHAICNNHPGTFRCECVEGYRFSEEG-TCVAVVDQRPINYLHDCDIPERAQCIYLGGALYTCSCLPGFSGDGRACQDQPSRCHPDAFCYNTPGSFMCQCKPGYQGDGFRCVEKTRCQLEREHLL---GPADAQRPWPPGLFCDEHGHAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMRPPCLSTVAHGPAVPTAVIPLPPGTHLLFAQTGKIERLPLAGSMTKTDAKALLHAPDKVIIGLAFDCVDQMVYWTDISEPSIGRASLHGGEPTTILRQDLGSPEGIALDHLGRNIFWTDSHLDRIEVAKLDGTQRRVLFDTDLVNPRGIVTDSVRGNLYWTDWNRDSPKIETSYMDGTNRRVLVQDDLGLPNGLTFDAYSSQLCWVDAGTSRAECLKPGQSRRKVLEGLQYPFAVTSYGKNLYYTDWKMNSVVAIDLAVSKETDTKQARLYGITTALSQCPEGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >XP_031408053.1 LOW QUALITY PROTEIN: nidogen-1 [Meleagris gallopavo] ---VRSRCAPSTPR-FPSYRSCSQHQREGCRQTPPRLRTPALWCERRRLMRAG-LEVLTVATNGIIAVNEPKNEEFPVSFGAIAPFMADLDTTDGRGSVYYREDSSSDVLQLASDYIKGGFPEAAFDPSSVVIVTWKLVAPYQGPGEDLTLEEKRNTFQAVLASSDSSSYAIFLYPEDGLQFYAYSKNNIPAMVGFSQASTNYFWENPGSYNVIANDEDSIRNLHKSSNAGRQGVWVFEIGSSTIVPAKVS-ASLEPSEEDQESKPFMSDYTEEDQTYSVPQLAVHREFPTAKAPPRQFPAQQFPPQGPQVIDVEFDETGIVFRYHTDVQQTCANNRHQCSVHAICKDYPNGFCCSCIAGYKGNGRQCVAEGSPQRVNGKVKGRIFVGNNPVPVTFENTDLHSYVVMNHGRAYTAISTIPEALGYSLLPLASIGGVIGWMFAVEQQGYKNGFSITGGEFTRQTEVTFLGNNEKVVIKQKFSGIDEHGHLTISTEMEGRVPEVPAGASVHIEPYTELYHASSSVITSSSTREYTVTEPERDGVASYQWRQTISFDEIHDDTLHAAPATQQLSVDSIFVLYNDEQILRYAMSNSIGPISDGSADISRNPCYTGTHNCDTNAVCRAGSGNRFSCECSIGFRGDIDECSEQSNAVCNNQPGTYRCECVDGYQFAADGRTCVAV--EYAVNHTHGCDIPQRAQCVYTGGSAYVCTCLPGFSGDGRACEDQQGRCHPDAFCYNTPGSFSCQCKAGYRGDGFQCVVKTKCQREKEVALGS-GGTFFQREIRVGQFCDEHGNVPTQCHGSTGYCWCVDRDGNEIDGTRSXPGVRPPCLSTAAIGPSVRPDTIPLPPGTHLLFAQSGKIEHVPLEGNMKKNGAKALLHIPDKVIIGVAYDCMDKMVYWTDISGPSISRASLHGGEPTTIIRTDLGSPEGIALDHLGRNIFWTDSQLDRIEVARLDGRQRRILFDTGLVNPRAIVVDPVRGNLYWTDWNREAPKIETSYMDGTNRRILVKDDLGLPNGLTFDPYSSMLCWVDAGTKRLECMNPNQGRRKIVEGIQYPFGVTSYGKNLYYTDWRRDAVVAVDRMVSVENDNKRSRLYGITTAFAQCPGGHNYCTVNNGGCTHLCLATRSCRCPDNTVG >XP_003824554.1 nidogen-1 [Pan paniscus] RAAWTLPLLLAGPVGCLSRQELFPFGPGLELEDGDDLVSPALELSALRFYDRSDIDSVYVTTNGIIATSEPPAKEFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSITQRAAECVHRGFPEISFQPSSAVVVTWESVAPYQGPSRDPDQKGKRNTFQAVLASSDSSSYAIFLYPEDGLQFHTFSKKEVPAVVAFSQGSVGFLWKSNGAYNIFANDRESIENLAKSSNSGQQGVWVFEIGSPGVVPADVIEDGAEYDDEDEDTRLGLEDVRGGADTYSVPSVLSPLGPPTERTRSFQLAVETFHQQQPQVIDVEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGSSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPVGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGIDEHGHLTIDTELEGRVPQIPFGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPYQWRQTITFQEVHDDSRPALPSTQQLSVDSVFVLYNEEKILRYALSNSIGPVREGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDIDECSEQSHTICNNHPGTFRCECVEGYQFSDEG-TCVAVVDQRPINYLHNCDIPQRARCIYTGGSSYTCSCLPGFSGDGQACQDQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVEKTRCQHEREHILGAAGAADPQRPIPPGLFCDAHGHAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPCLSTVAQGPALPTAVIPLPPGTHLLFAQTGKIERLPLEGNMRKTEAKAFLHVPAKVIIGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDVFSSQLCWVDAGTNRAECLNPSQSRRKALEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAKQTRLYGITTALSQCPRGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >XP_003993948.1 nidogen-1 [Felis catus] GAAWTLQLLLAGPGGCLSRQELFPFGPGLELEAGDDQVSPALELRALRFFDKSDINSVYVTTNGIIAMSEPPAKEFPPTFGVVAPFLADLDTTDGFGKVYYREDLSPSVTRLAAECVQRGFPEISFQPSSAVVVTWESVAPYQGPSKDPAQEGKRNTFQAVLASSDSSSYAIFLYPEDGLQFDTFSKKDVPAVVAFSQGVQGFIWKSDGAYNIFANDRESIGNLAKSSNSGQQGVWVFEIGSPGVVPSDVSDDGAEYDDEDYDTHLGLEDVSGDPSMHSVPWVLSPPGPPTERTRSFQLPGERFHQQHPQVIDVEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDFATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVRGRILVGNSPVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPVGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGYPGKLVIKQRFSGIDEHGHLTITTELEGRVPQIPFGSSVHIEPYTELYHYSPGVITSSSTREYTVMEPEQDGAAPYQWRQTITFQEAHDTSRLALPNTQQLSVDSVFVLYNEESILRYALSNSIGPVKDGSPDALQNPCYIGTHGCDTNAACRPGPGVQFACECSIGFRGDIDECSEQSHAICNNHPGTFRCECVEGYQFSEEG-TCVAVVDQRPINYLHDCDIPQRAQCIYMGGSSYTCSCLPGFSGDGRACRDQPSQCHPDAFCYNTPGSFTCQCKPGYRGDGFHCVEKTRCQLEREHILGAAGAADPPR---PGLFCDEHGHVPTQCHGSTGYCWCVDRDGRELEGTRTRPGMRPPCLSTVAHGPSVPTAVIPLPPGTHLLFAQTGKIERLPLEGSMQKSEAKTLLHAPDKVIIGLAFDCVDKMVYWTDISEPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSHLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRESPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSAQLCWVDAGTSRVECLKPGQSRRKVLEGLQYPFAVTSYGKHLYYTDWKMSSVVAVDLAISKETDTKQTRLYGVTTALSQCPQGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >XP_011960995.3 nidogen-1 [Ovis aries] GAAWTLQLLLAGPGGCLSRQELFPFGPELELEAGDDLVSPALELSALHFFDRSDIDSVYVTTNGIIAMSEPPAKEFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSVTQLAAECVQRGFPEVSFKPSSAVVVTWESVAPYQGPSKDPTLEGKRNTFQCILASSDSSTYAIFLYPEDGLQFYAFSKKEVPAVVAFSQGLTGLIWKSDGAYNIFANDRESVGNLAKSSNSGLQGIWVFEIGSPGVIPADVNDDGAEYDDEDYDTHLGLEDAREDSGTHNTPSDLSPLTPPTEKTRSFQLPGERFPQQQPQVIDVEVEETGIVFSYNTDSRQTCTNNRHQCSVHAQCRDFATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGDSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPDKLTIKQQFSGIDEHGHLTIDTELEGRVPQIAFGSSVHIEPYTELYHYSRQVITSSSTREYTVTEPEQHGTAPYQWRQTITFQEVHDDSRPVLPSTQQLSVDSVFVLYNEERILRYALSNSIGPVRDGSPDALQNPCYIGSHGCDANAACRPGPGTQFTCECSIGFRGDIDECSEQNHAVCNNHPGTFRCECVEGYRFSEAG-TCVADVDLRPINHLHDCDIPQRAQCKFMGHGSYTCICLPGFSGDGRACQDQPSRCHPDAFCYNTPGSFVCRCKYGYQGDGFHCVEKTRCQQERERVV---GTADSPRPQPPGLFCDEQGHVPTQCHSSTGYCWCVDRDGQEVEGTRTGSGMRPPCLSTVAFGPPVLTAVIPPPPGTHLLFAQTGKIERLPLEGSMTKSEAKTLLHAPDKVIIGLAFDCVDKMIYWTDISQPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSQLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCWVDAGTHRAECLNPGQNIRKVLEGLQYPFAVTSFGKNLYYTDWKTNSVVAVDLAVSKEMDSKQTRLYGITSALSQCPEGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >XP_018887566.2 nidogen-1 [Gorilla gorilla gorilla] RAAWTLPLLLAGPVGCLSRQELFPFGPGLELEDGDDLVSPALELSALRFYDRSDIDSVYVTTNGIIATSEPPAKEFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSITQRAAECVHRGFPEISFQPSSAVVVTWESVAPYQGPSRDPDQKGKRNTFQAVLASSDSSSYAIFLYPEDGLQFHTFSKKEVPAVVAFSQGSVGFLWKSNGAYNIFANDRESIENLAKSSNSGQQGVWVFEIGSPGVVPADVIEDGAEYDDEDEDTRLGLEDVRGGADTYSVPSVLSPLGPPTERTRSFQLAVETFHQQHPQVIDVEVEETGVVFSYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGSSQIPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPVGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIKQRFSGIDEHGHLTIDTELEGRVPQIPFGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPYQWRQTITFQEIHDDSRPALPSTQQLSVDSVFVLYNEERILRYALSNSIGPVREGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDIDECSEQSHTICNNHPGTFRCECVEGYQFSDEG-TCVAVVDQRPINYLHNCDIPQRARCIYTGGSSYTCSCLPGFSGDGQACQDQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVEKTRCQHEREHILGAAGAADPQRPIPPGLFCDAHGHAPTQCHGSTGYCWCVDRDGREVEGTRTRPGMTPPCLSTVAQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLEGNMRKTEAKAFLHVPAKVIIGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVTGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAFSSQLCWVDAGTNRAECLNPSQPRRKVLEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAKQTRLYGITTALSQCPQGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >XP_004077531.1 nidogen-1 [Oryzias latipes] ----QTFLGLVASAHSIRRDEFFPFGESQVLEPENDR-TQRLDLSPLLFYDRS-FDSIFINTNGFVATEEPPSESMPPSFGMIAALHGDLDTSAGVGKVFFRQDSRADVLRRAAEHINRAFPYNEVDPTHAVVVTWVDVAPHTPHTRGDGLEKKRNSFQLVLASLQKASYAILLYARDGVQFSTLVQ--VIVHAGFSKGQVPFWFTSQGPYRTTSDEEISVRELAEQTNSGQRGVWVYEIGTSNVVPGEVT-------DLPTE--PPLAQTD-------------------------EIHSNQYQPLDPEVVVLETDINVDVFSYNFG---TCSNNRNKCSQFADCRDYSSGFCCHCRPGFYGNGIQCVAEGKPQRMNGKIHGRVFVGSSPYPVELGGVDLHSYVVVNDGRSYVAISDIPETLGPSLLPLSVLGGVIGWAFALEQPGYRNGFSIIGGEFTREAEVTFMPWNEKLIIRQEFKGTDELDHLVVKTTLEGKVPEMPLGSTVTMDPYAEIYQYGSNLITSSSTREYKVTMPD----GSYQCRQTITFQSQHGDSLRDVKPSQMLSVDQVFVLYDNNKILRYAMSNKVGDVNGGEPQ--QNPCFTGRHGCDNNAVCRPGQGSQFTCECAAGFLDDIDECRENYNAVCNNQPGTYRCECEDGFQFGSDGRTCVEV--DRPVNHTHDCDAPERAQCSYTGSSSFICSCLPGFVGDGRNCQDQSRRCHQDADCFNTPGSFVCRCRQGYRGDGSYC-RRTRCEEERDSLLGGTFGPRGPRP-S-ESHCDGNGEEPLQCDRRTGSCWCVDRNGVEVRGTRSAPGSTPMCIHDDGVRPTPRPDVDPLPPGTHLLFAQSGRIEHVPLESYMRKEGAKAVLHLPERVIIGVAYDCVEKVVYWTDITSPAISKASIQGGEPTTVIRTDLGSPEGITVDHIGRTIFWTDSMKDRIEVASLDGSRRRVIVDSDLINPRAIVADPVHGHLYWTDWNREAPKIETSYMDGSNRRVLVQNDLGLPNGLTYDFQSSLLCWADAGTHKMECMHPDRDRQSVMEGIQYPFGITSYGRKIFYTDWKRNAVVAMDRHSGRESDEKQTKLYGITSAYSQCPPGRNYCSVNNGGCTHLCLATRSCKCPNNPAT >XP_021151656.1 nidogen-1 isoform X1 [Columba livia] --GGKLTLHCKLPN--------------------------------------------KVATNGIIAVNEPSSEEFPVSFGAIAPFMADLDTTDGRGNVYYREDSSSDVLQRASDYIRSGFPETTFDPSSVVIVTWKLVAPYQAPGEDHGLEEKRNTFQAVLASSDSSSYAIFLYPEDSLQFYTYSKNNIPAMVGFSQASTNYFWEKPGSYNVIANDEDSIRNLHKSSNAGKQGVWVFEIGSSSIVPAKIS-ESLEFDEQDQESKPFMSDYTEDDQTYSVPQLAAHQDFPTAKAPPRPFQVQQFPPQQPQVIDVEFDETGIVFRYHTDVQQTCANNRHQCSVHAICTDYPNGFCCSCIAGYKGNGRQCVAEGSPQRVNGKVKGRIFVGNNPVPVTFENTDLHSYVVMNQGRAYTAISTIPETLGYSLLPLASIGGIIGWMFAVEQQGYKNGFSVTGGEFTRQTEVTFLGNNEKLVIKQRFSGIDEHGHLTISTEIEGRIPEIPSGASVHIEPYTELYHTSSSVITSSSTREYTVTEPERDGVASYQWRQTISFDEIHDDSHHAASATQQLSVDSVFVLYNDEQILRYAMSNSIGPISDGSADINRNPCYTGTHNCDTNAICRPGTGNRFLCECSIGFRGDVDECSEQNNAVCNNQPGTYRCECVEGYQFAADGRTCVAV--DYAINHTHNCDIPQRAQCVYTGGSAYICTCLPGFSGDGRACEDQQGHCHPDAFCYNTPGSFSCQCKAGYRGDGFRCVEKTKCQREREVALGS-VGTFFPREIRVSHFCDEHGNLPTQCHSSSGYCWCVDRDGNEIDGTRSGPGVRPPCLSTAAIGPSVRPDTVPLPPGTHLLFAQSGKIEHVPLEGNMKKNGAKALLHIPDKVVIGVAYDCTDKMVYWTDISGPSISRASLHGGEPTTIIKTDLGSPEGIAVDHLGRNIFWTDSQLDRIEVARLDGRQRRILFDTGLVNPRAIVVDPMRGNLYWTDWNREAPKIETSYMDGTNRRILVKDDLGLPNGLTFDPYSSMLCWVDAGTKRLECMNPNQGRRKIVEGIQYPFSVTSYGKNLYYTDWRRDAVVAVDRTISIENDNKRSRLYGITTAFAQCPGGHNYCTVNNGGCTHLCLATRSCRCPDNTVG >XP_017897955.1 PREDICTED: nidogen-1 [Capra hircus] GAAWTLQLLLAGPGGCLSRQELFPFGPELELEAGDDLVSPALELSALHFFDRSDIDSVYVTTNGIIAMSEPPAKEFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSVTQLAAECVQRGFPEISFKPSSAVVVTWESVAPYQGPSKDPTLEGKRNTFQCILASSDSSTYAIFLYPEDGLQFYAFSKKEVPAVVAFSQGLTGLIWKSDGAYNIFANDRESVGNLAKSSNSGLQGIWVFEIGSPGVIPADVNDDEAEYDDEDYDTHLGLEDARGDSGTYNTPSDLSPLTPPTEKTRSFQLPGERFPQQQPQVIDVEVEETGIVFSYNTDSRQTCTSNRHQCSVHAQCRDFATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGDSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRQAEVTFVGHPDKLTIKQQFSGIDEHGHLTIDTELEGRVPQIAFGSSVHIEPYTELYHYSRQVITSSSTREYTVTEPEQHGTAPYQWRQTITFQEVHDDSRLVLPSTQQLSVDSVFVLYNEERILRYALSNSIGPVRDGSPDALQNPCYIGSHGCDANAACRPGPGTQFTCECSIGFRGDIDECSEQNHAVCNNHPGTFRCECVEGYRFSEAG-TCVADMDLRPINHLHDCDIPQRAQCKFMGHGSYTCICLPGFSGDGRACQDQPSRCHPDAFCYNTPGSFVCRCKYGYQGDGFHCVEKTRCQQERERVV---GTADSPRPQPPGLFCDEQGHVPTQCHSSTGYCWCVDRDGQEVEGTRTGSGMRPPCLSTVAFGPPVLTAVIPPPPGTHLLFAQTGKIERLPLEGSMTKSEAKTLLHAPDKVIIGLAFDCVDKMIYWTDISQPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSQLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSMRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCWVDAGTHRAECLNPGQNIRKVLEGLQYPFAVTSFGKNLYYTDWKTNSVVAVDLAVSKEMDSKQTRLYGITSALSQCPEGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >XP_006258247.1 PREDICTED: nidogen-1 [Alligator mississippiensis] --GWGALLALAGPG--RCGPPLLPFGSEAELEAGDDVTSPALELSPLHFYGSA-VHSVHVATNGIIGMNKPSKEEFPISFGAIAPFMADLDTTSGHGKVFYREDSSPDVLQLVVSYIRRGFPEVTFDPISVVIVTWARVAPYRTPSEDAVLEDKRNTFQAVLASSDSSSYAVFLYPEDGLQFWTHSKNAIPATVGFSQASTNLLWEKLGSYNIVAHDEESIRSLYKSSNIGKPGVWVFEIGSSIILPAKVS-ESLEYNEEYQELQPSVSYHKGGDQSYGVPQSATQADFVTGKTPPDPFQVQRFYQQEPQVIDVEFDETGIVFRYNTDVQQTCANNRHQCSIHAVCKDYSNGFCCSCIAGYKGNGRQCVAEGSPQRVNGKVKGRIFVGNNPVPVVFENTDLHSYVVMNQGRAYTAISTIPETLGYSLLPLASVGGIIGWMFSVEQQGYKNGFSLTGGEFTRQAEVIFLGNNEKLVIKQKFNGIDEHGHLTISTEMEGRIPEISFGASVHIEPYTELYHSSTSVITSSSTREYTVTPPERDGSSSYQWRQTISFDEIHDDSHHPVSATQQLSVDSIFVLYNDEQILRYAMSNSIGPVSDGSADINRNPCYTNSHDCDSNAVCRPGTGNQFSCECSVGFQGDVNECSEQSNAVCNNQPGTYRCECVDGYQFSADGRSCVAI--EHVINHTHNCDIPQRAQCTYVGGSSFICSCLSGFSGDGRACVDQQNRCHPDAFCYNTPGSFRCQCKAGYRGDGFQCVEKTKCQHERELALGS-HIPRGSRP--VGDFCDEYGNKPTQCHSSSGYCWCVDSYGNEIDGTRSGPGIRPPCLSTAAIGPSVRPDSIPLPPGTHLLFAQSGKIEHVPLEGNMKKTDAKALLYVPDKVVIGVAYDCKDKMVYWTDISGPSISQVSLHGGEPTAIIKTDLGSPEGIAIDHLGRNIFWTDSQLDRIEVARLDGNQRRVLFDSDLVNPRAIVADAVKGNLYWTDWNRDAPKIETSYMDGTNRRILVKDDLGLPNGLTFDIYSSMLCWADAGTKKLECMNLSQGRRKVLEGILYPFSITSYGKNLYYTDWRRDAVVAVDRTVSKENDNKRSRLYGITTALAQCPPGHSYCEVNNGGCTHLCLTTRSCRCPDNTVG >XP_015799438.1 PREDICTED: nidogen-1 [Nothobranchius furzeri] ----QSLVVFWASVRSIRREEFFPFGPSQLLESGDDQ-TFRLTLSPVLFYDGS-FDSLYINTNGFVATKEPLNESLPPEFGAMAPLHGDLDTSDGVGKVYFRQDNSPDVLRQAAEHINRGFPEEEVNPINTVVITWVDIASHKPQTRGDGAERKRNTFQLVIASLETASYAIVLYARNGIQFTTLVE--VVMHAGFSQGLVKFFYSSQGNYRTTTDDEASVRALAEETNSGLRGVWVYGIGTSNVVPGVVT-------DLPAEDTQQHTDG--------------------------EINPLRYQPQNPEVVVVDPEINVDVFSYNLG---SCANNRNKCSQFADCRDYASGFCCHCRPGYYGNGLQCVAEGKPQRMNGKLRGKVFVENSPSPVEFNGNDLHSYVVVNDGRSYVAISDIPTSVGPSLMPLLALSNVIGWVFALEQPGFRNGFSIIGGEFTRQAEVTFQPGNEKLIIRQEFEGTDELDHLVVSTTMDGRVPAVPPGSTVQIDPYTDVYQYDSNLITSSSTRYYTVTNPD----GSYQCRETITFQSQHDESLRDVT-TQMLKVDQIFVLYDNNNLLRYAMSNKIGDVNGGQTE--ENPCFTGRHGCDTNAVCRPDQGSQFTCQCASGFSGDIDECTENPNAICNNQPGTFRCECEDGYQFGSDGRTCIEV--DRPVDHTHTCDIPDRAQCSYTGGSSYICSCLPGFVGDGRICQDQPGRCHQNAVCVNTQGSFLCQCLPGYSGNGVYC-TKTRCEAHRDNVLSTMAHPRGARP-PISQYCDENGNLPMQCHGSTGYCWCVDRNGLEISGTRSAPSSRPMCIDHNTVGPWPRPDVIAPPPGTNLLFAQSGRIEHIPLEGYMKKHDAKAVLHLPEKVIIGVAYDCVEKMVYWTEITSPSISKASMLGGEPTAVIRTDLESPEGITIDHLGRTMFWTDSMRDRIEVASLDGSQRRVLIDTDLVNPRAVIADPVSGNLYWSDWNRDAPKIETSHMDGSNRRVLVKDSLTLPNGLTYDSQSSLLCWADAGTHKMECMNPSRDRSTVLEGIRYPFGMTSFGKTIYYTDWQRDAVVSVDRYAEKETDEKRTRPYGIAAAYPQCLSGQNYCSVNNGGCTHLCLATRSCKCPDNAVA >XP_020764015.1 nidogen-1 [Odocoileus virginianus texanus] GAAWTLQLLLAGPGGCLSRQELFPFGPELELEAGDDLVSPALKLSALHFFDRSDIDSVYVTTNGIIAMSEPPAKEFPPTFGAVAPFLADLDTTDGLGKVYYREDLSPSVTQLAAECVQRGFPEVSFKPSSVVVVTWESVAPYQGPSKDPALEGKRNTFQSILASSDSSTYAIFLYPEDGLQFYTFSKKEVPAVVAFSQGLVGLIWKSDGAYNIFANDRESIGNLAKSSNSGQQGIWVFEIGSPGVVPADVNDDGAEYDDEDYDTHLGLEDVGGDGGIYNTPSDLSPLTPPTERTRSFQLPGERFPQQQPQVIDVEVEETGIVFSYNTDSRQTCTNNRHQCSVHAQCRDFATGFCCHCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGASQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPIGGIIGWMFAVEQDGFKNGFSITGGEFTRRAEVAFVGHPDKLIIKQQFSGIDEHGHLTISTELEGRVPQVAFGSVVHIEPYTELYHYSRQVITSSSTREYTVTEPERDGTAPYQWRQTITFQEVHDDSRPVLPSTQQLSVDSVFVLYNEERILRYALSNSIGPVRDGSPDALQNPCYIGSHGCDANAACRPGPGTQFTCECSIGFRGDIDECSEQNHAICNNHPGTFRCECVEGYRFSEAG-TCVAVMDQRPVNYLHDCDISQRAQCIYTGGSSYTCSCLPGFSGDGRACKDQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFHCVEKTRCQREREHIL---GAVDSQRPRPPGLFCDDHGHAPMQCHGSTGYCWCVDRDGREVQGTRTRPGMRPPCLSTVAHGPPVPTAVIPLPPGTHLLFAQTGKIEHLPLEGSMTKSEAKTLLHTPDKVIIGLAFDCVDKMVYWTDISQPSIGRASLHGGEPTTIIRQDLGSPEGIALDHLGRNIFWTDSHLDRIEVAKLDGTQRRVLFETDLVNPRGIAADSVRGNLYWTDWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAYSSQLCWVDAGTHRAECLKPGQNRRTVLEGLQYPFGVTSFGKNLYYTDWKTNSVAAVDLAISKETDSKQTRLYGITSALSQCPEGHNYCSVNNGGCTHLCLATRTCRCPDNTLG >XP_030297897.1 nidogen-1 [Sparus aurata] ----RSFLGFVASVESITRGELFPFGPSRLMEAGNDQ-THRLQLDPVLFYDGS-FDSIFINTNGFVATAEPTSESMPPGFGMIAALQGDLDTRDGEGRVYFRQDSSRDALRRSAEIINRAFPEDEFNPTHAVVITWVDVTAHEPHSRGDG-NRKRNTFQLVIASMETASYAIVLYPRDGIQFTTPAN--VVMHGGFSKGLVKFLFSSQGPYRTTTEDEASIRALAEETNSGQRGVWVYEIGTSNVVAGEVT-------DLPAERRPAYTDGE-------------------------EVHPVQYQPHNPEVVVVDTDINVDVFSYNLG---TCANNANKCSQFADCKDYSSGYCCHCRPGFYGNGIQCVAEGKPQRMNGKVYGKVYVGNSPSPVEFTSNDLHSYVVVNDGRSYVAISEVPYTLGPSLQPLSALGGVIGWAFALEQPGFKNGFSIIGGEFTRQAEVTFLPGNEKLTIRQEFKGIDEHDHLAVSTTLEGRVPEVPRGSTVQIERYSEIYQYSNNLITSSSTRDYVVSLPD----GSYQWRQTITFQSQHGDSLRDMKPTQMLSVDQVFVMYDNNELIRFAMSNKIGDVNGGQPQ--ENPCFTGRHGCDTNAVCRPGEGTQFNCECAAGFNGDIDECAENFHAICNNQPGTFRCECEDGYQFGNDGHTCTEI--DRVVDATHDCDIPERAQCSYTGGSSFICSCLPGFFGDGRVCKDQPGRCHQDAVCYNTQGSFTCQCRSGYYGDGFYC-TKTQCETHRDSLLG--AGPRGPRP-PIGQYCDENGAEPMQCHSSTGHCWCVDRNGQEIPGTRSGPGSRPMCINHGGVGPTPRPDVHPLPPGTHLLFAQSGRIEHVPLEGHMKKEDAKAVLHLPEKVIIGVAYDCVEKMVYWTEITSPSISKASIQGGEPTEVIRSDLDSPEGIAVDHLGRTLFWTDSVKDRIEVASLDGSQRRVIIDSDLVNPRAIITDPPNGNLYWTDWNRDAPKIETSYMDGSNRRVLVKDDLGLPNGLTYDPQSSMLCWADAGTHKMECTHPARDRRQVMEGIQYPFGITSFGKNIYYTDWRRDAVVAVDRYAGKESDQKRTKLYGITTAYAQCPSGQNYCAVNNGGCTHLCLATRSCKCPNNAVG
PhyML tree of selected proteins (OWK09497_1_NID2__Cervus_elaphus_hippelaphus_:0.28389096,XP_040188888_1_nidogen_2__Rana_temporaria_:0.32272189,((XP_039259166_1_nidogen_like__Styela_clava_:1.85786412,(CAE1252257_1_LRP4__Sepia_pharaonis_:3.16594398,((XP_038046995_1_fibropellin_1_like_isoform_X27__Patiria_miniata_:0.51615245,XP_791550_3_nidogen_1__Strongylocentrotus_purpuratus_:0.82875186):0.44391165,(XP_031557799_1_nidogen_like__Actinia_tenebrosa_:1.34018974,(NP_001256467_1_NIDogen__basement_membrane_protein___Caenorhabditis_elegans_:1.35026421,(KAG9432604_1_nidogen_2__Apis_mellifera_carnica_:0.88962634,ACK77669_1_RE69505p__Drosophila_melanogaster_:1.15310128):0.29752365):0.16373792):0.18694858):0.08651192):0.18640685):0.38621021,((XP_018118629_1_nidogen_1_isoform_X1__Xenopus_laevis_:0.33007608,((XP_006258247_1_PREDICTED__nidogen_1__Alligator_mississippiensis_:0.13307256,(XP_021151656_1_nidogen_1_isoform_X1__Columba_livia_:0.03743813,(XP_031408053_1_LOW_QUALITY_PROTEIN__nidogen_1__Meleagris_gallopavo_:0.05106049,XP_040524442_1_nidogen_1_isoform_X1__Gallus_gallus_:0.00847511):0.0444127):0.07295222):0.09889604,(XP_017203089_1_PREDICTED__nidogen_1__Oryctolagus_cuniculus_:0.07708667,(((NP_035047_2_nidogen_1_precursor__Mus_musculus_:0.01996302,XP_213954_4_nidogen_1__Rattus_norvegicus_:0.02725937):0.08900824,((XP_020929417_1_nidogen_1_isoform_X1__Sus_scrofa_:0.05265423,((XP_020764015_1_nidogen_1__Odocoileus_virginianus_texanus_:0.01755759,(KAF4018772_1_hypothetical_protein_G4228_010616__Cervus_hanglu_yarkandensis_:0.00186603,XP_043332969_1_nidogen_1_isoform_X1__Cervus_canadensis_:0.00185644):0.01129873):0.01186961,(NP_001094625_1_nidogen_1_precursor__Bos_taurus_:0.02474438,(XP_011960995_3_nidogen_1__Ovis_aries_:0.00186689,XP_017897955_1_PREDICTED__nidogen_1__Capra_hircus_:0.00559374):0.03413737):0.0174713):0.0351995):0.01200791,(XP_546076_2_nidogen_1__Canis_lupus_familiaris_:0.04091128,XP_003993948_1_nidogen_1__Felis_catus_:0.036655):0.02181321):0.02378111):0.00635083,(XP_024106979_1_nidogen_1__Pongo_abelii_:0.00611531,(XP_018887566_2_nidogen_1__Gorilla_gorilla_gorilla_:0.00288528,(sp_P14543_NID1_HUMAN_Nidogen_1_OS_Homo_sapiens_OX_9606_GN_NID1_PE_1_SV_3:0.00462276,(XP_003824554_1_nidogen_1__Pan_paniscus_:0.00091831,XP_001156001_1_nidogen_1__Pan_troglodytes_:0.00091651):0.00274916):0.00264286):0.00226519):0.0442174):0.01209087):0.21149509):0.08296659):0.09968948,(tr_F1RAG3_F1RAG3_DANRE_Nidogen_1a_OS_Danio_rerio_OX_7955_GN_nid1a_PE_1_SV_2:0.35940387,(XP_030297897_1_nidogen_1__Sparus_aurata_:0.10898407,(XP_015799438_1_PREDICTED__nidogen_1__Nothobranchius_furzeri_:0.18550737,XP_004077531_1_nidogen_1__Oryzias_latipes_:0.21259906):0.02831284):0.08244269):0.28525508):0.26192566):0.38667262);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)