PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0075 | P14543 | Nidogen-1 | NID1 | NID | Homo_sapiens | Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions. |
Domains | Gene Ontology |
PF00058 (3_Ldl_recept_b) PF00086 (Thyroglobulin_1) PF06119 (NIDO) PF07474 (G2F) PF07645 (EGF_CA) PF12662 (cEGF) PF12947 (2_EGF_3) |
GO:0005201 (enables) extracellular matrix structural constituent
GO:0005509 (enables) calcium ion binding GO:0005518 (enables) collagen binding GO:0043236 (enables) laminin binding GO:0043237 (enables) laminin-1 binding GO:0043394 (enables) proteoglycan binding GO:0050840 (enables) extracellular matrix binding GO:0007155 (involved in) cell adhesion GO:0007160 (involved in) cell-matrix adhesion GO:0010811 (involved in) positive regulation of cell-substrate adhesion GO:0030198 (involved in) extracellular matrix organization GO:0032836 (involved in) glomerular basement membrane development GO:0071711 (involved in) basement membrane organization GO:0005886 (is active in) plasma membrane GO:0005576 (located in) extracellular region GO:0005604 (located in) basement membrane GO:0031012 (located in) extracellular matrix GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome GO:0071944 (located in) cell periphery |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |