PB0070

DATABASE

Click here to access PB0070 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0070	Q14112	Nidogen-2	NID2	NID-2	Homo_sapiens	Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions.

Domains

Gene Ontology

PF00058 (2_Ldl_recept_b) PF00086 (2_Thyroglobulin_1) PF06119 (NIDO) PF07474 (G2F) PF07645 (EGF_CA) PF12662 (cEGF) PF12947 (EGF_3)

GO:0005201 (enables) extracellular matrix structural constituent GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0005518 (enables) collagen binding GO:0007155 (involved in) cell adhesion GO:0007160 (involved in) cell-matrix adhesion GO:0071711 (involved in) basement membrane organization GO:0005615 (is active in) extracellular space GO:0005576 (located in) extracellular region GO:0005604 (located in) basement membrane GO:0005886 (located in) plasma membrane GO:0031012 (located in) extracellular matrix GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|Q14112|NID2_HUMAN Nidogen-2 OS=Homo sapiens OX=9606 GN=NID2 PE=1 SV=3 MEGDRVAGRPVLSSLPVLLLLPLLMLRAAALHPDELFPHGESWGDQLLQEGDDESSAVVK LANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRG RVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELN TFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGP YFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGRSF SHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDTKPLEESST LDPHTKEGTSLGEVGGPDLKGQVEPWDERETRSPAPPEVDRDSLAPSWETPPPYPENGSI QPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASGHTTPLSRGTYEVGLEDNIGSNTEVFTY NAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHL HVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPG SENGFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVSANFT AHISPYKELYHYSDSTVTSTSSRDYSLTFGAINQTWSYRIHQNITYQVCRHAPRHPSFPT TQQLNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPGNPCYDGSHMCDTTARCHPGT GVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRH TCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVDECSENR CHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQQRHAQAQYAYPGARFHI PQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTICE RWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQPGT TPACIPTVAPPMVRPTPRPDVTPPSVGTFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLH GSIIVGIDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTM YWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSL DGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFS IVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYLPEQRSHLYGITAVYPYCPTGRK >tr|X1WE42|X1WE42_DANRE Nidogen 2a (osteonidogen) OS=Danio rerio OX=7955 GN=nid2a PE=1 SV=1 MLTSCMCTSCSPKMTRDKIALLFLQLSWAFHHVAGIDRHDIYPYGMFYGDVTLQEGDDET SKVITLSKPMHFYEAPFTNLYVTTNGIISTQDLPMEKQYVDDGFPTDFPVIAPFLADIDT SKGKGSIYYRQTESPTVLKRAEADVKRGFPDATFSPTHAFIATWENVSAYEEVARSSSPS HRVNTFQVVLAYNEKDTYALFLYPEDGLQFFGTRPKESYNVEIELPARVGFSRGEISYLI FSRTEGPYYSLTSNEQSVKNLYQKGNIGEPGVWLFHVGNLYSFQNVVPAQQEAVSSKSPT VQDTVFTDEDYTDEEEYDPIDPDFQDPTTTEFLEPEPDSSLLERLNQETPLGQSPLQPSV SGPEDLPQPDPHHVQPEDNTQPQWPLPKHAILQVYPNRVKDVPTHPSDGQVFSVEEKVDF DSGVIHYSTDNKETCERFQQQCSLNAHCTDHSTGFCCHCNSGFYGNGRHCLPNGAPQRVN GKVRGTVLVGGTAVDLGNIDLHAYIVVGDGRAYTAISEVPEPAGWALMPVAPIGGLFGWL FALELPNSLNGFSITGAEFTRRADVTFSPGNQRLSIVQTATGLDNQNYLNVDTHLQGSVP FIPPGATVQMEPFKDTYQYYPSLITSTSVREFKVVSAENGAETFTFQVKQNITYRDCSHR PRSRLETLELKMERVFVMYVREERILRYAITNKIGPLGAVDPEPENVNPCYSGNHDCDTT ARCVPGEGQLFSCQCATGYRGDGRNCYDVDECAEGLSSCGAHSHCVNLPGSHRCQCESGF QFGFDGRTCQDVDECGEQPCHAQALCSNSPGSFRCQCQPGYHGDGFQCHPQNGHPKTRCE QHRDSLQSGDGGVPAVGAFIPQCDEEGQYRPLQCHGSTGHCWCVDNRGQERAGTRTPPGS PPRNCDEPVRPKTHCEQHRDSLQSENGGVPVVGAFIPQCDEEGQYRPQQCHGSTGHCWCV DNRGQERAGTRTPPGSPRVNCDQPVHLRTRCEQHRDSLQSGDGGVPAVGAFIPQCDEEGQ YRPQQCHGSTGHCWCVDNRGQERAGTRTPPGSPRVNCDQPVRPKTHCEQHRDSLQSGDGG IPVVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDSRGQERAGTRTPPGSPRVNCDQPVRSK THCEQHRDSLQSGDGGVPVVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDNRGQERAGTRT PPGSPRVNCDQPVIVPPTQRPESVCERWRASLLQQYGGQPDSQHYLPQCDSAGEFNPVQC YGGSSYCWCVDANGREVPGTRSHDAVKPACIPTVASPTVHPLPRPDVTPPPTGTSLLYAQ GQQIGVLPLNGTQMDKERSSVLLALHGSIVVGIDYDCRERKVYWTDLAGRTINRASLDPG SEPEIIINTALTSPEGLAVDVARRRLFWVDSTLDKIETANLDGSDRHVLFATDLVNPRAM IVDSSTGTLYWTDWNREAPKIESSSVDGQNRRVLVQEGIGLPNALTYDSTMRQVCWADAG TKRLECISPNGTGRRVIQSNLNYPFSMVYFANHYYYTDWRRDGVISLGRDNQLTDEYLPD QRSHLYGITVAPPQCL
Selected proteins from model organisms >sp|Q14112|NID2_HUMAN Nidogen-2 OS=Homo sapiens OX=9606 GN=NID2 PE=1 SV=3 MEGDRVAGRPVLSSLPVLLLLPLLMLRAAALHPDELFPHGESWGDQLLQEGDDESSAVVK LANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRG RVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELN TFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGP YFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGRSF SHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDTKPLEESST LDPHTKEGTSLGEVGGPDLKGQVEPWDERETRSPAPPEVDRDSLAPSWETPPPYPENGSI QPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASGHTTPLSRGTYEVGLEDNIGSNTEVFTY NAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHL HVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPG SENGFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVSANFT AHISPYKELYHYSDSTVTSTSSRDYSLTFGAINQTWSYRIHQNITYQVCRHAPRHPSFPT TQQLNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPGNPCYDGSHMCDTTARCHPGT GVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRH TCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVDECSENR CHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQQRHAQAQYAYPGARFHI PQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTICE RWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQPGT TPACIPTVAPPMVRPTPRPDVTPPSVGTFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLH GSIIVGIDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTM YWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSL DGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFS IVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYLPEQRSHLYGITAVYPYCPTGRK >tr|X1WE42|X1WE42_DANRE Nidogen 2a (osteonidogen) OS=Danio rerio OX=7955 GN=nid2a PE=1 SV=1 MLTSCMCTSCSPKMTRDKIALLFLQLSWAFHHVAGIDRHDIYPYGMFYGDVTLQEGDDET SKVITLSKPMHFYEAPFTNLYVTTNGIISTQDLPMEKQYVDDGFPTDFPVIAPFLADIDT SKGKGSIYYRQTESPTVLKRAEADVKRGFPDATFSPTHAFIATWENVSAYEEVARSSSPS HRVNTFQVVLAYNEKDTYALFLYPEDGLQFFGTRPKESYNVEIELPARVGFSRGEISYLI FSRTEGPYYSLTSNEQSVKNLYQKGNIGEPGVWLFHVGNLYSFQNVVPAQQEAVSSKSPT VQDTVFTDEDYTDEEEYDPIDPDFQDPTTTEFLEPEPDSSLLERLNQETPLGQSPLQPSV SGPEDLPQPDPHHVQPEDNTQPQWPLPKHAILQVYPNRVKDVPTHPSDGQVFSVEEKVDF DSGVIHYSTDNKETCERFQQQCSLNAHCTDHSTGFCCHCNSGFYGNGRHCLPNGAPQRVN GKVRGTVLVGGTAVDLGNIDLHAYIVVGDGRAYTAISEVPEPAGWALMPVAPIGGLFGWL FALELPNSLNGFSITGAEFTRRADVTFSPGNQRLSIVQTATGLDNQNYLNVDTHLQGSVP FIPPGATVQMEPFKDTYQYYPSLITSTSVREFKVVSAENGAETFTFQVKQNITYRDCSHR PRSRLETLELKMERVFVMYVREERILRYAITNKIGPLGAVDPEPENVNPCYSGNHDCDTT ARCVPGEGQLFSCQCATGYRGDGRNCYDVDECAEGLSSCGAHSHCVNLPGSHRCQCESGF QFGFDGRTCQDVDECGEQPCHAQALCSNSPGSFRCQCQPGYHGDGFQCHPQNGHPKTRCE QHRDSLQSGDGGVPAVGAFIPQCDEEGQYRPLQCHGSTGHCWCVDNRGQERAGTRTPPGS PPRNCDEPVRPKTHCEQHRDSLQSENGGVPVVGAFIPQCDEEGQYRPQQCHGSTGHCWCV DNRGQERAGTRTPPGSPRVNCDQPVHLRTRCEQHRDSLQSGDGGVPAVGAFIPQCDEEGQ YRPQQCHGSTGHCWCVDNRGQERAGTRTPPGSPRVNCDQPVRPKTHCEQHRDSLQSGDGG IPVVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDSRGQERAGTRTPPGSPRVNCDQPVRSK THCEQHRDSLQSGDGGVPVVGAFIPQCDEEGQYRPQQCHGSTGHCWCVDNRGQERAGTRT PPGSPRVNCDQPVIVPPTQRPESVCERWRASLLQQYGGQPDSQHYLPQCDSAGEFNPVQC YGGSSYCWCVDANGREVPGTRSHDAVKPACIPTVASPTVHPLPRPDVTPPPTGTSLLYAQ GQQIGVLPLNGTQMDKERSSVLLALHGSIVVGIDYDCRERKVYWTDLAGRTINRASLDPG SEPEIIINTALTSPEGLAVDVARRRLFWVDSTLDKIETANLDGSDRHVLFATDLVNPRAM IVDSSTGTLYWTDWNREAPKIESSSVDGQNRRVLVQEGIGLPNALTYDSTMRQVCWADAG TKRLECISPNGTGRRVIQSNLNYPFSMVYFANHYYYTDWRRDGVISLGRDNQLTDEYLPD QRSHLYGITVAPPQCL >NP_032721.2 nidogen-2 precursor [Mus musculus] MFRDPTAGWLTPPSPLSLLVMLLLLSRVGALRPDELFPYGESWGDQLLPEGDDESSAAVKLAIPLRFYDA QFSSLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSHSRGRILYREDTSGAVLSLAARYV RTGFPLSGSSFTPTHAFLATWEHVGAYEEVSRGAAPSGELNTFQAVLASDESDTYALFLYPANGLQFFGT RPKESYNVQLQLPARVGFCRGEADDLKREALYFSLTNTEQSVKNLYQLSNLGIPGVWAFHIGSRFALDNV RPATVGGDPSTARSSALEHPFSHAAALESYTEDSFHYYDENEEDVEYPPVEPGEAPEGHSRIDVSFNSKA DPGLVDVGTSSPGSDRASPWPYPAPGNWPSYRETESASLDPQTKQGRPVGEGEVLDFRDPAELLDQMGTR APAPPEADAALLTPVNEDLGGRNTQSYPEAGPVPSEPDVPVPPLEGEVLPHYPESGHVPPLRGGKYVIGL EDHVGSNDQVFTYNGANLETCEHSHGRCSQHAFCTDYTTGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVS GRLRVGHIPVHFTDVDLHAYIVGNDGRAYTAISHVPQPAAQALLPVLPIGGLFGWLFALEKPGSENGFSL TGATFVHDVEVTFHPGEERVRITQTAEGLDPENYLSIKTNIEGQVPFIPANFTAHITPYKEFYHYRDSVV TSSSSRSFSLTSGSINQTWSYHIDQNITYQACRHAPRHLAIPATQQLTVDRAFALYSEDEGVLRFAVTNQ IGPVEVDSAPVGVNPCYDGSHTCDTTARCHPGTGVDYTCECTPGFQGDGRSCVDVNECATGFHRCGPNSV CVNLVGSYRCECRSGYEFADDQHTCILIAPPPNPCLDGSHTCAPEGQARCIHHGGSSFSCACLPGFIGTG HQCSDVDECAENRCHEAAICYNTPGSFSCRCQPGYRGDGFHCTSDTVPEDSISGLKPCEYQQRYAQTQHA YPGSRIHIPQCDDQGNFVPLQCHGSTGFCWCVDRNGHEVPGTQTPPGSTPPHCGPPPEPTQRPRTVCERW RESLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGRELQGTRSQPGTRPACIPTVAPPV VRPTPRPDVTPPSVGTFLLYAQGQQIGHLPLNGSRLQKDAARTLLSLHGSIVVGIDYDCRERMVYWTDVA GRTISRASLEAGAEPETIITSGLISPEGLAIDHFRRTMYWTDSGLDKIERAELDGSERKVLFHTDLVNPR AITVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINKDIGLPNGLTFDPFSKLLCWADAGTKKLECTL PDGTGRRVIQNHLNYPFSIVSYADHFYHTDWRRDGVISVNKDSGQFTDEFLPEQRSHLYGITAVYPYCPT GRK >NP_001012005.2 nidogen-2 precursor [Rattus norvegicus] MSWDPTAGRLAPPSPLSLLLVLVLLSRVGALRPEELFPYGESWGDRLLPEGDDESSAAVKLAVPLRFYDA QFSNLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSHSRGRILYREDTSQAVLSLAARYV RTGFPLTGSSFTPTHAFLATWEHVGAYEEVRRGAAPSGELNTFQAVLASDESDTYALFLYPANGLQFFGT RPKESYNVQLQLPARVGFCRGEADDLKREALYFSLTNTEQSVKNLYQLSNLGIPGAWAFHIGSRLALDNV RPATVGGDHSTARSSALEHSFNHAAALESYTEDSFDYYNENEEDVEYPPIEPGEALEGHSRIDVSFNSEV NPTSPDSDHASPLPHPAPGNWPSYRETESASLDPQTKQGPPVGEVEVLDFKDPAELLDQTGTRTPAPPGA DAAFLTPGREDLGNRDTQSYPEARPVPSEPDVPVAPLEREILPNYPESGHVPPLSGGRYVVGLEDHVSSK DQVFTYNGANRETCEHSHGQCSRHAFCTDYTTGFCCHCQSRFYGNGRHCVPEGAPHRVNGKVSGHLQVGH MPVHFTDVDLHAYIVSNDGRAYTAISQIPQPAAQALLPVLPIGGLFGWLFALEKPGSENGFSLTGATFVH DVEVTFHPGEERVRITQTAEGLDPENYLSLNTNIEGQVPFIPANFTAHIAPYQEFYHHRDSVVTSSSSRS FSLISGSINQTRSYRIDQNITYKACSHAPRHLAVPATQQLTVDRAFALYSEEEGVLRFAVTNQIGPVEVD SAPTAVNPCYDGSHTCDTTARCHPGTGVDYTCECTPGFQGDGRSCVDVNECATGFHRCGPNSVCVNLVGS YRCECRSGYEFADDRHTCVLIAPPPNPCLDGSHTCAPEGQARCIHHGGSSFSCACLPGFVGTGHQCSDVD ECAENRCHGAAICYNTPGSFSCRCQPGYHGDGFHCASDTVPEDSISGLKPCEYQQRYAQAQHAHAGSRIH IPQCDDQGNFVPLQCHGSTGFCWCVDQNGHEVPGTQTPPGSTPPHCGPPPEPTQRPRTVCERWRESLLEH YGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGRELPGTRSQPGTMPACIPTVAPPVVRPTPRP DVTPPAVGTFLLYAQGQQIGHLPLNGSRLQKDAARTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRA SLEAGAEPETIITSGLISPEGLAIDHFRRTMYWTDSGLDKIERAGLDGSERKVLFHTDLVNPRAITVDPI RGNLYWTDWNREAPKIETSSLDGENRRILINKDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRR VIQNHLNYPFSVVSYADHFYHTDWRRDGVISVSKDSGQLTDEYLPEQRSHLYGITAVYPYCPTGRK >CAE1293091.1 LRP5_6 [Sepia pharaonis] MLPPGYIKYHSQHSCVGSIERGFLCFGSPLLLFANRKDVRLVDAANSRNSSVIISGLEDAAAVDFYYAENSVFWTDVSLE MIKRTYVNGSQTSTNVITFGLLSPDGLALDWLGEKLYWTDSETNRIEVSNLNGSCRKILFWEHLDQPRAIALDPLNGYMY WTDWGERPKIERAGMDGSKQNRSVIISERIHWPNGLTLDYEDSKIYWADAKLNFIHSCNFDGSDRQPVVQGSLPHPFALT LFEERLFWTDWHTRAIHSCHKRTGGNREVVHSDIYSPMDIHVYTAKRQPASNNPCGNNNGGCSHLCLMSPQPPFFSCACP TGVRLHENGHTCASSPKEILLLARRSDLRRISLDTPDYTDVILQLSDIRHTIAIDYDTVEDYVYWTDDEVHLIRRAHMDG SGQEVIVSTEVEHPDGVAVDWIGRNLYWTDTGTDRIEVCRLNGTSRKVLISEGLVEPRAICLDPMRGHMYWTDWGANPKI ERANMDGTERIALINSSLGWPNGVAIDYQEKKLYWGDAKTDMIEVANLDGTDRKVLVSNNLPHIFGFSLLGDYVYWTDWQ RRSIERVHKVTGGERQVIIDQLPDLMGLKAVNMNHVEGSNGCAENNGGCSHLCLNTHPKGPVCACPTGIFFELLDDQKTC VVPDGFLLFSRKEDIRRMSLETNHNDVLIPIQGVKDAHALDFDNSDNRIYWTDASLKQISRAFMNGSSLEHIIEFGIEFP EGMAVDWVAKNLYWTDIGTKRIEVARLDGKSRRVLIWKDLSDPRSIVLDPPNGYMYWTDWGENPKLERATLDGKNRKTSD MLGQDRRVMVDTHLLSPRGITQYKDFIYWTDLEKKSIERAHKLTGHNRTTIHQGHGDYVMDILVFQESRQPGWNPCGVDN GNCSHLCLAHPSPPDQTGTANMTFSCACPTHYTLDADNKTCLRK >XP_015132255.2 nidogen-2 isoform X1 [Gallus gallus] MRAAVAALAAAAVAVAAALPRTELLPYGAAHGDGRLRHGDDESSPGVVLRPPMRLYGRAARRLFVGTNGV ISTQDFPGETQYVDDDFPTDFPVIAPFLADLDTSGGRGDIYYRQDRAPTVLEWAAGYVHAGFPDTAGTFV PSSAFIATWEDVGAHGEPPGKLNTFQAILAYNEEETYAIFLYPEGGLQFLGTRPKESYNVQLELPARVGF SRGDGDDGKREGHSYSVASSQQELQRLERESNVGVPGVWVFRVGTLENVEPGDVPGAALSPAPHGTDDTS VPTELLAQPGSRTTSPHPHPALLSIVPSGLPASPLGQEWSPRLHSIGDAPQGHPVSYSSGQHGVGVEEDV HFNTNVFTYSAGSRETCAQHHGRCSPHAFCTDYATGLCCHCRAAYYGNGRQCLPEGAVHRLNGKVSGSLV VGRTPVRFQDVDLHAYIVGSDGRAYTAISGVPAPAARALLPLLPLGGLFGWLFALEEPGSENGFSITGAE FTQYLEVTFYPGEEQVRITQMAEGLGADNYLSLRTHIEGQVPFVPENTSVHIAPYKELYHYSSSAVTSSA HRDYVLTSGSTNQTLSYRLRQNITVVGCPHARGRLPTVQQLSVARAFALYDGHEQVLRYALTSRISSSRG DAEVPPVNPCHDGTHACEETARCQPGTGLGYTCECAAGYRGDGRGCQDVDECEEGLGQCGPFSVCLNVLG SYRCECHSGYRPAEDGHGCVLPTPAADPCEVGRHPCAPRDRARCLPRAGGQPACECLPGYAGDGRVCSDV NECTLNLCHPAAICYNTPGSFSCQCQPGYEGDGFQCTHAQSSTQRLTPCEHEQLYPRTPGHVPQCDEQGG YQPLQCHSGSGHCWCVDSSGQEIAGTRTAAGSTPPRCGNPGSSQQLTPCEHERLYPRAVPPGPSPVGNGH VPQCDEQGNYRPLQCHGSTGYCWCVDGAGQEIAGTRTAPGSTPPRCGSPEPSERPPTMCERWRQSLLEHY GGSPRGDQYVPQCDAHGHFTPLQCHGDSGYCWCVDESGREIQGTRSEPGSPPPCLPSVAPPTVRPSPRPD VSPPAAGTFLLYAQGQQIGYLPLNGTRLQKEAAKTLLSLHGSIVVGIDYDCREKTIYWTDVAGRTISRAS LEPGAEPETIINSGLISPEGLAVDHLRRAMFWTDSGLDKIERAQLDGSERRVLFDTDLVNPRAITVDPVR GNLYWTDWNREAPKIETSTVSGANRRVLVNTDIGLPNGLTFDPFSKLLCWADAGTKKLECTFPDGAGRRI IHNNLNYPFSIISYASHFYHTDWRRDGVIAVNKETGSFTDEYLPEHRSHLYGITAVYPYCPGARK >XP_009426087.1 nidogen-2 isoform X1 [Pan troglodytes] MEGDRVAGRPVLSSLPVLLLLPLLMSRAAALHPDELFPHGESWGDQLLQEGDDESSAVVKLANPLHFYEA RFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAMAPFLADIDTSHGRGRVLYREDTSPAVLGLAARYV RAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTR PKESYNVQLQLPARVGFCRGEADDLKSEGPYFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVR PAAVGDLSAAHSSVPLGRSFSHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKV DTKPLEGRISPPDSHLSSPLHPTPTYWPFYPETESSTLDPHTKEGTSLGEVEGPDLKGQVEPWDERGTRS PAPPEVDRDSLAPSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASGHTTPLSRGTY EVGLEDNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVN GKVSGHLHVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGSEN GFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVPANFTAHISPYKELYHYS DSAVTSTSSRDYSLTFGAINQTWSYRIHQNITYQVCRHAPRRPSFPTTQQLNVDRVFALYNDEERVLRFA VTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCG PNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAAAGQARCVHHGGSTFSCACLPGY AGDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSQTPCEQQQRHAQAQYAY PGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTICERWR ENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMV RPTPRPDVTPPSVGTFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAG RTISRASLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRA IAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLP DGTGRRVIHNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYLPEQRSHLYGITAVYPYCPTG RK >XP_038443101.1 nidogen-2 isoform X1 [Canis lupus familiaris] MRGDRAARRLALPPLPLPPPPLLLLLLLARAAALHPGELFPYGQSRGDQLLQEGDDESSAAVKLASPLHF YEAQFSYLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSQGRGRVLYREDTSLAVLGQAA RYVRAGFPRTAARFTPTHAFLATWEQVGAYEEATSRAPPSGELNTFQAVLASDESDTYALFLYPANGLQF FGTRPKESYNVQLELPARVGFCRGETDDLKREGPYFSLTSTEQSVKNLYQQSNLGIPGVWAFHIGSTSPL DNIRPATIGGDLTKAHPSPPPEQSFRPEAALESDYTEDNLDYYDENEGEVEYPPSEPEEAWNGHSSIDVS FQAKAELGPGGGGISPPDSVPASPLPPHLTASDGQSYPETESATLDPQTKEGRVLEGRDVPDLNGRVESS EQPGTRGPAPSEIESDSLDPTRGTPPPHPGRGAPLSEEDVPPAHPGGKEVLLNYSVPAHTPLGQGRQVLG VEDVIGSSTEVFTYNAANKETCEHNHRQCSRHAFCTDYTTGFCCHCQSRFYGNGKHCLPAGAPHRVNGKV SGHLRVGHLPVHFSDVDLHAYIVSNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFS FTGATFTHDMEITFYPGEERVQITQTAEGLDPENYLSIKTNIQGQVPYIPANFTAHIAPYKEVYHYLDSA VTSTSSRDYSLIFGAINQTRSYRIYQNITYQACRHAPRHWAIPTTRQLNVDRVFALYTEEESLLRFAVTN QIGPVEENSEPTPVNPCYDGSHTCDITARCHPGTDVDYTCECASGYQGDGRSCVDVNECATGSHHCGPNS MCVNLPGSYRCECRSGYELADDRHTCVLIAPPSNPCEDDSHTCAPAGQARCIYHGGSTFSCACLPGYTGS GHQCTDVDECSENRCHPSATCYNTPGSFSCQCHPGYHGDGFQCTPDPASGLKPCEQQQHHAHAQQAYPGS QLHIPQCDDQGHFLPLQCHSSTGFCWCVDPDGHEVPGTRTPPGSTPPHCRPPEPTQRPQTVCERWRENLL EHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTVRPVP RPDVTPPSVGTFLLYAQGQQIGHLPLNGTKLQKDLAKTLLSLHGSIVVGIDYDCHERMVYWTDVAGRTIS RASLQPGAEPETIINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERKALFHTELVNPRAIAVD PIRGNLYWTDWNREAPKIETSSLEGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTG RRVIQNNLNYPFSIVSYADHFYHTDWRRDGVISVNRDSGQFTDEYLPEQRSHLYGITAVYPYCPAGRK >NP_001095535.1 nidogen-2 precursor [Bos taurus] MRGDQAAGWPAPPPPPLLLMLLLLLSRAAALHPSELFPYGQSRGDQLLQEGDDESSAAVKLTLSLRFYDA QFSDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLYRQDTSPGVLGLAASYV RTGFPLSGAHFTPTHAFLATWEQVGAYEEAKRGAPPSGELNTFQAVLASDEFDTYALFLYPANGLQFFGT RPKESYNVQLQLPARVGFCRGEVDDLNRQGPYFSLTSTEQSVKNLYQHSNLGIPGVWAFHIGSTSPLDNV RPATIGGDLSKARPSAPLGQSFSHAVALEDDYTQDTLDDYDENEEEIEYPPSEPAEASNGHSSVDVSLGG RISAPDSDLASPEPRSASQSGPETESSPLDPHTKERRLQGETDAPDLKGRVKSSEQPGTRVPAPPETEGD SPAPPGEAPPPSPEGGAGPADQDALPAHPGGEAALPNYPGPDHGPHLGQRGQVVGVEDDISSNTEVFTYN AANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKQCLPEGAPHRVNGKVSGHLLVGHTPVHFTD VDLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFY PGEERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFSAHVAPYKELYHYADSAVTCTSTRTYSLMSGA INQTQTYRIHQNITYQVCRHAPRHWAVPVTQQLNVDRVFALYSDEEKVLRFAVTNQIGPVEGDSEPTPVN PCYDGSHTCATTARCHPATGVDYTCECASGYQGDGRNCVDVNECATGFHRCGPNSVCVNLLGSYRCECRS GYEFADDRHTCILITPPPNPCEDGHHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTDVDECSENRC HPSATCSNTPGSFSCRCQPGYYGDGFQCTPEPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHF TPLQCHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTVRPTPRPDVTPPPVGTFLLYAQGQQIG HLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPEMVVNSGLISPE GLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSS LDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQNNLNYPFNIVSYADHFY HTDWRRDGVIAVNRDTGQFTDEYLPEQRSHLYGITAVYPYCPGRK >XP_020957573.1 nidogen-2 isoform X1 [Sus scrofa] MRGYRGARRPALRAPPLLLLLLLSRAVALQPDELFPYGQSLGDQLLQEGDDESSAAVKLALPLRFYDAQF SDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSHGRGRVLYREDTSPDVLSLAARYVRT GFPRSAAHFVPTHAFLATWERVGAYEEPKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRP KESYNVQLELPARVGFSRGEVDDLKREEQYFSLTSTEQSVKNLYQHSNLGIPGVWAFHIGSASPLDNVKP AIAGGDLSKAHPSVPLRHSSSHAVAPEGEDTEDNLDYYDENEEEVEYPPGETEEESNGHSPDDVSFHSRA DLKPSGGGISLPGSDLPSPLPRPTSRDGLETESATLDPQTKEGRPQEEIDAPDLKGRGETSEQPGAQVPA PPKTERDSPDPSWAALPPHPDEGALPAERDVPPVPSGGEVVLPNYPRRPDHAPPLGRGRQVVGVEDDIGS NTKVFTYNAANRETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVG HTPVHFTDVDLHAYVVGNDGRAYTAISHIPQPAAQALLPLMPIGGLFGWLFALEKPGWENGFSLTGATFI HDMEVTFHPGGERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFTVHITPYKELYHYSGSAVTSTSSR AYSLTYGAINQTRSYSIHQNITYQTCRHAPRHWAIPTTQQLNVDRVFALYTDEEKVLRFAVTNQIGPVEG DSEPAPVNPCYDGSHTCATTAQCHPATGVDYTCECASGYQGDGRRCVDVNECATGFHRCGPNSVCVNLPG SYRCQCRSGYEFVDDRHTCVLIAPPPNPCEDGSHNCAPTSQARCIHHGGRSFSCACLPGYAGDGHQCADV DECSENRCHPSATCSNTPGSFSCHCQPGYHGDGFQCTPDPALGLKPCEHQQREAQAQRTHPGARLHIPQC DEQGHFLPLQCHGSTGFCWCVDPNGQEVPGTRTPPGSLPPHCGPPEPTQRPRTVCERWRESLLEHYGGTP RDDQYVPQCDDLGHFTPLQCHGKSDFCWCVDQDGREVQGTRSQPGTTPACIPTVAPPTMRPTPRPDVTPP PVGTFLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPG AEPETIVNSGLISPEGLAIDHFRGTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIRGNLY WTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNN LNYPFSIVSYADHFYHTDWRRDGVISVNRDSGQFTDEYLPEQRSHLYGITAVYPYCPTGRK >XP_008267875.2 PREDICTED: LOW QUALITY PROTEIN: nidogen-2 [Oryctolagus cuniculus] MARTLGRQRPRTPRLPPGAWDWARRGPLLPRRRPWTWTAPGSPDGRAAGAAEDEGSAQPRPAAASPSPYV DDDLPXDFPAIAPFLADIDTSGGRGRVLYRQDSSPAVLGLAARYVSAGFPRAAAPFSPTHAFVATWDQVG AYEEVRRGAAPSEELNTFQAVLVSDESDAYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEADD LKREGQYLSLTRTEQSVKNLYQLSNVGIPGLWAFHIGSASPLDNVRPAAVGGALPAAHSSTPLKHPFSHA VALKADHPEDSLDYYDENEEEVEYPPAEPEAATVDIAFHSSTDSGPVAGGLSPPDSDLASPLPPPASSER PSHLHSESTTGEPPSKQEARLQEVPSPERRPGAQPLGQTGAGSVAVPAVDGDSVAPAQEAPTRYPDDAGD TLPRYSVPSLSAPVGGGRYVAGVEEDITSNAEVFTYNAAHKETCERNHGQCSAHAFCTDYTTGFCCHCQS SFYGDGKHCLPEGAPHRVNGKVSGHLRVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPPPAAQALLPLT PLGGLFGWLFALEKPGSENGFSLTGATFVQDTEVTFYPGEERLRITQTAEGLDPENYLSMKTSIQGQVPY VPANSTAHLAPYKEIYHHSDSAVTSTSSRDYYLTFGAVNQTGSYRIHQNITYQGCRHAPSHRAIPAAQQL TVDRVFALYSEEEGVLRFAVANQIGPVEGDSDPAPVNPCYDGSHTCDMTARCHPGPGTHYTCECTPGYQG DGRSCVDVNECATGFHRCGPNSMCVNLPGSYRCECRSGYTFADDQHTCILMAPPPNPCENGTHTCAPAEQ ARCIPHGDGTFSCACLPGYAGDGHQCSDVDECSENSCHPAATCYNTPGSFSCHCQPGYLGDGFQCTPDSS SGLKACQQQQLYAQAQHARPGTRLHIPQCDEQGDFLPLQCHGSTGFCWCVNSDGHEVPGTRTPPGSTPPH CGPPPGPTQRPRTVCERWKESLLEHYGGTARDDQYVPQCDDLGRFVPLQCHGKSDFCWCVDKDGREVAGT RTQPGVTPTCLPEAVPPLIGAMPRPEDSLTGSFLVYAQGQRLGRLPFKRTKLLKDQASTLLSMHGSIIVG LDYDCHERKVYWTDVAGRVISRIGMQPGAEPEVIINSGLLRPEGVAIDFIHRTMYWTDSGLDQIVRTNLD GSEREILFYVDLVNPRAITVDPVGGNLYWTDWNRDAPKIERSSLDGTGRRILIGKDIGLPNGLNFDPVTE MLCWADAGTRKLECTLRDGTGRRVIQSNLNYPFSMVSYIDHFYYTDWRRDAVISVNANTGAVTEEYLPEQ RSHLYGITAVFPYCPTGSK >XP_002824786.2 nidogen-2 isoform X1 [Pongo abelii] MEEDRVAGRPALSSLPVLLLLPLLMSRSAALHPDELFPHGESWGDQLLQEGDDESSAVVKLANPLHFYEA RFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRGRVLYREDTSPAVLGLAARYV RAGFPRSARFTPTHAFLATWKQVGAYEEVKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTR PKESYNVQLQLPARVGFCRGEADDLKSEGPYLSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSLLDNVR PAAVGDLSAAHSSVPLGRSFSHATALESDYNEDNLDYYDVNEEEAEYLPGELEEALNGHSSIDVSFQSKV DTKPLEESSTLDPHTKEGTSLGEVEGPNLKGQVEPWDERGTRSPAPPEVDRDSLAPSWETPPPYPENGSI QPYPDGGPVPSEMDVPPAHPEEEIVLRNYPASGHTTPLSRGTYEVGLEDNIGSNTEVITYNAANKETCEH NHRQCSWHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHLHVGHTPVHFTDVDLHAYIVG NDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGSENGFSLAGAAFTHDMEVTFYPGEERVRIT QTAEGLDPENYLSIKTNIQGQVPYFPANFTAHISPYKELYHYSDSAVTSTSSRDYSLTFGAINQTWSYRI HQNITYQVCRHAPRHPSFPTTQQLNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPVNPCYDGSHMC DTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRH TCILITRPANPCEDGSHTCAPAGQAQCIHHGGSMFSCACLPGYAGDGHQCTDVDECSENRCHPAATCYNT PGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQHRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGF CWCVDPDGHEVPGTQTPPGSTPPHCGPPPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFI PLQCHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTIAPPTARPTPRPDVTPPSVGTFLLYTQGQQIGY LPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRASLELGAEPETIVNSGLISPEG LAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSL DGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRHVIQNNLKYPFSIVSYADHFYH TDWRRDGVVSVNKHSGQFTDEYLPEQRSHLYGITAVYPYCPTGRKM >XP_010710486.1 nidogen-2 [Meleagris gallopavo] MFLPGCGERREERSSGPPGPARPQLAAIPAPGAAPRYPARRGMGMREEEEKGGREGRTTPGRILGRAARR LFVGTNGVISSQDFPGETQYVDDDFPTDFPVIAPFLADLDTSGGRGDIYYRQDHTPSVLEQAAGYVHAGF PYTTGTFVPSSVFVATWEDVGAHGEPPGKLNTFQAILAYNEEDTYAIFLYPEGGLQFLGTRPKESYNVQL ELPARVGFSRGDGDDGKREGHSYNVASSQQELQRLERESNVGMPGVWVFHVSTLENVEPRNGPGAALSSA PHGTDDTSVPTELLAQPGSRTTSPHPHPALLSIVPSGLPASPLGQEWSPRLHFGDAPQGHPVSYSSGQHG VGVEEDVHFNTNVFTYSAGSRETCAQHHGRCSPHAFCTDYATGLCCHCRAAYYGNGRQCLPEGAVHRLNG KVSGSLVVGRTPVRFQDVDLHAYIVGSDGRAYTAISGVPAPAARALLPLLPLGGLFGWLFALEEPGSENG FSITGAEFTQYLEVTFYPGEEQVHITQTAEGLGADNYLSLKTHIEGQVPFVPESTSVHIAPYEELYRYSS SAVTSSAHRDYVLTSGSTNQTLSYRLHQNITVTGCPHARSHLPTVQQLSVARAFALYDGHEQVLRYALTS RISSTHDDAEVPPVNPCHDGTHACEETARCQPGTGLGYTCECAAGYRGDGRGCKDVDECEEGLSQCGPFS ICLNVPGSYRCECHSGYRPAEDGHGCVLPTPAADPCEVGRHPCAPRDRARCLPRAGGQPACECLPGYAGD GRVCSDVDECTLNLCHPAATCYNTPGSFSCQCQPGYEGDGFQCTHAQSSTQRLTPCEHERLYPRTPGHVP QCDEQGSYRPLQCHSGSGYCWCVDASGQEIAGTRTAAGSTPPRCGNPGSSQQLTPCEHERLYPRAVPPGP SPVGNGHVPQCDEQGNYRPLQCHGSTGYCWCVDSAGQEIAGTRTAPGSTPPRCGNPEPSERPPTMCERWR QSLLEHYGGSPRGDQYVPQCDAQGHFTPLQCHGDSGYCWCVDESGREIQGTRSEPGSPPPCLPSVAPPSI RPSPRPDVSPPAAGTFLLYAQGQQIGYLPLNGTRLQKEAAKTLLSLHGSIVVGIDYDCREKTIYWTDVAG RTISRASLEPGAEPETIINSGLISPEGLAVDHLRRAMFWTDSGLDKIERAQLDGSERRVLFDTDLVNPRA ITVDPVRGNLYWTDWNREAPKIETSTVSGANRRVLVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECTFP DGAGRRIIHNNLNYPFSIISYASHFYHTDWRRDGVIAVNKETGSFTDEYLPEHRSHLYGITAVYPYCPGA RK >XP_008955315.2 nidogen-2 isoform X1 [Pan paniscus] MEGDRVAGRPVLSSLPVLLLLPLLMSRAAALHPDELFPHGESWGDQLLQEGDDESSAVVKLANPLHFYEA RFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAMAPFLADIDTSHGRGRVLYREDTSPAVLGLAARYV RAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTR PKESYNVQLQLPARVGFCRGEADDLKSEGPYFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVR PAAVGDLSAAHSSVPLGRSFSHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKV DTKPLEGRISPPDSHLSSPLHPTPTYWPFYPETESSTLDPHTKEGTSLGEVEGPDLKGQVEPWDERGTRS PAPPEVDRDSLAPSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASGHTTPLSRGTY EVGLEDNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVN GKVSGHLHVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGSEN GFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVPANFTAHISPYKELYHYS DSAVTSTSSRDYSLTFGAINQTWSYRIHQNITYQVCRHAPRRPSFPTTQQLNVDRVFALYNDEERVLRFA VTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCG PNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGY AGDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSQTPCEQQQRHAQAQYAY PGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTICERWR ENLLEHYGGTPRDDQYVPQCDDLGLFIPLQCHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMV RPTPRPDVTPPSVGTFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAG RTISRASLELGAEPETIVNSGLISPEGLAVDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRA IAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLP DGTGRRVIHNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYLPEQRSHLYGITAVYPYCPTG RK >XP_023111456.1 nidogen-2 [Felis catus] MRGDRALPPPLLPLLLLLLLSRAAALRPDELFPYGQSWGDQLLQEGDDESSAAVKLASPLRFYEAQFSYL YVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSQGRGQVLYREDTSRAVLDLAARYVRSGFP RTAAHFTPTHTFLVTWKQVGAYEETTRRAPPSEERNTFQAVLASDESDTYALFLYPANGLQFFGTRPKES YNVQLELPARVGFCRGEVDDLKREGPYFSLTSTEQSVKNLYQQSNLGAPGVWAFHIGSTPRLDNIRPATV GGDLSKGHSAAPPERSFGLPEVLASDYTEDNLDYYDENENEGGVEYTPSEPEEALNGHSSVDVSFQSKAE SRPMGGGMSPPNSDLASPLPHLTSSNWPFYPETESATLNPQPKEGRHPWGMDTPDLNVRVESSEQPGTRG PAPSEVEGESLDPSQGTLPPYPENKSINPYTYGGAPPSEADVPPALPEGKVVLLNYPLPAHSIPLGRGRQ VLGVEDVITSNTEVFTYNAADKETCERNHGQCSPHAFCTDYTTGFCCHCQSRFYGNGKHCLPEGVPHRVN GKVSGHLRVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWEN GFRLTGATFTHDMEVIFYPGEERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFTAHMAPYKELYHYT DSAVTSTSSRDYSLILGGINQTLSYRIYQNITYQACRHAPRHRAIPKTQQLNVDRVFALYTDGEGVLRFA VTNQLGPVEVDSTPTPVNPCFDGSHTCDTKARCHPGTGVDYTCKCASGYQGDGRSCVDVNECATGFHHCG PNSVCTNLPGSYSCDCRSGYEFADDHHTCILIAPPPNPCADGSHSCAPADQARCIYHGGSTFSCTCLPGY TGNGHQCTDVDECSENRCHPSATCYNTPGSFSCRCLPGYHGDGFQCAPDPTSGLKPCERQQRSAHAQHTY PGSRVHIPQCDEQGHFLPLQCHGSTGFCWCVDPNGHEVPGTRTPPGSTPPHCGPAEPTRRPRTVCERWRE NLLEHYGGTPRDDQYVPQCDDLGHFTPLQCHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPTAR PLPRPDVTPPSVGTFLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGR AISRASLEPGAEPETIISSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERKALFHTDLVNPRAI AVDPIRGNLYWTDWNREAPKIETSSLEGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPD GTGRRVIQNHLNYPFSIVSFADHFYHTDWRRDGVISVNRDSGQFTDEYLPEQRSHLYGITAVYPYCPTGR K >XP_004010577.3 nidogen-2 [Ovis aries] MRADRAAGRPALPPPPLLLMLLLLLSRAAALHPSELFPYGQSRGDQLLQEGDDESSAAVKLTLSLRFYDA QFSDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLYRQDTSPAVLGLAANYV RTGFPLSGAHFTPTHAFLATWEQVGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGT RPKESYNVQLQLPARVGFCRGEVDDLNRQGPYFSLTSTEQSVKNLYQHSNLGIPGVWAFHIGSTSPLDNV RPATVGGVLSKAHPWAPLGQSFSHAVALEDDYTQDTLDEYDENEEEIEYPPSEPAEASNGHSTIDVSLGG RISAPDSDLASPVPRSASRGGPETEASPLDPHTEERRPQGETNAPDLKQRVESSQQPGTRVPAPPETEGE SPAPPGEAPPPSLEGGAGPADQDALPAHPGGEAALPNYPGPDHAPHLGHRRQVVGVEDDISSNTEVFTYN AANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTD VDLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFY PGEERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHHADSAVTSTSTRTYSLMSGA INQTQSYRIHQNITYQVCRHAPRHWAVPVTQQLNVDRVFALYSDEEKVLRFAVTNQIGPVEGDSEPTPVN PCYDGSHTCATTARCHPATGVDYTCECASGYQGDGRSCVDVNECATGFHRCGPNSVCVNLLGSYRCECRS GYEFADDRHTCISITPPPNPCENGRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTDVDECSENRC HPLATCSNTPGSFSCRCQPGYYGDGFQCTPEPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHF TPLQCHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTSRPTPRPDVTPPPVGTFLLYAQGQQIG HLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPEMVINSGLISPE GLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSS LDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQSNLNYPFNIVSYADHFY HTDWRRDGVIAVNRDTGQFTDEYLPEQRSHLYGITAVYPYCPGRK >XP_011482732.1 nidogen-2 [Oryzias latipes] MDRGSLLTVSLLCWSCGAVTAIRRADLFPFGTSSGDSLLAEGDDETSKVLILPKPFYFYNSQFSLLYVAT NGIVSAQDLPMEKQYVDDGFPTDFPVVAPFLADIDTSGGRGQIYYRVTETPSVLNRLTWEVSRGFPDAKF TPTHAVVATWENVAAYEEPSRSSGSSNRVNTFQAVIAYDETDSYVLFLYPEDGLNFFGTRPKESYNVEIE LPARVGFSRGEVTYFFFSRSEGPSYSVTSDEQSVKNLNRVGNTGTPGLWLFHTGHRYSFDNVIPASVGGP IVTAPPRRFVPDTTTPEYEVIYTLGPEIHEDDEYSLTGRGPAASNHFQYLQPGSPEPSYSPPEDSGHQVL LGSEPRYGPEPAGRQYAPPEQPQRVLEGGARQGQEQIPQLPLEVVDLYPPDRNTPGGYVVNVEEDDVHFD TRVIQYTTDNKETCARFQQQCSQNAFCSDYATGFCCHCQPGFYGNGRDCLPEGAPQRVSGKVSGTVSVQS TPVTLNNIDLHAYIVVGDGRAYSAISEVPEPLGWALMPVSPIGELFGWLFALELPNSQAGFKSTGAKFTR HAEVQFYPGNHRLSILQTGRGLDEHNLLNVDTVVSGNVPFIPPEAEITVEPFKETYQYYPSVVTSTSARE IKVVSASRGAESYSLNLKQNITYRECRHDNRASNPETLQITMERVFVMYDKDERILRYAVTNKIGPVGAD PVAPELINPCYSGNHDCDTTAMCIPQEDQNYECQCATGYGGDGRNCYDIDECAEGVSSCGEHSECLNLPG SHRCLCSRGFEFAYDGRTCVDIDECSSSPCHINARCINELGSFQCLCQPGFTGDGFFCSQQEDLPARPKT RCEHHRESVQRTTEEGAPLLGVYVPQCDESGKYLPQQCHDSTGYCWCVDSTGQERTGTRTPPGSALVDCS RTDEQPHYKTRCERHREHVLASEREDRPSVGAYVPQCDQNGEYVPQQCHTSTGYCWCVDGMGQERSGTRS APGSPSMDCSKPDEALQPKTPCERLRESVLASSAGGRPLAGAYAPQCDEDGHYVPRQCHGSSGYCWCVDS SGQERPGTRTSPGAPSVDCSRAEEPEAPKTECELLRERAMASSPEAVPAAGRFVPQCDAEGRYLSQQCHG STGHCWCVDSRGQERPGTRTPPGVAQVDCYQRPEPEPPYTRPESVCERWRASLMEHYGGKPQPQQYLPQC RSDGEFSPVQCYGETTYCWCVDQDGREIDGTRSHDAVKPACLSSVAPPTVLPLPRPDVTPPTNADVTLLY AQGQKIDALPLNGTKLHANGSKTLLTLHGSIVVGIAYDCRENQVYWTDLSARTINRASLVSGSEPEILIS SNLESPEGLAVDVQRRLMFWVDSSPDNIEVANLDGSERRTLFDTDLVNPRAIIVVSSKGTLYWTDWNREA PKIECSTVNGQNRRVVVSDGVGLPNALAYDHATDQVCWADAGTKRLECVSPNGSGRRVIHRNLNYPFSMV YYRDHFYYTDWRRDGVIAVNRDSNKLTEEYLPDQRSHLYGIAVATNHCLQGSH >XP_013223751.1 nidogen-2 isoform X1 [Columba livia] MAREGHVVSRLSTLCPRGGTCWGTHGRGTSAAPEHLVPLSLQVGTNGVISTQDFPRETQYVDDDFPTDFP VIAPFLADLDTSGDRGNIYYRQDDSPDVLHQAAGYIQAGFPHIAGSFMPTNAFIATWEDVGAYQELSQDT KPSQKLNTFQAVVAYDDEDTYAIFLYPKGGLQFLGTRPKESYNVQLELPARVGFSWGDGDDPKRDGLFHS LASSERALRLLERESNTGIPGVWVFHVGSVSPLEHVEPGGGGGASPGVPQSPEPHVPDTAGYTHALYSHA DHVATNLPVRHGSAAMSPHPDHGHHAPTLLGIVPRGLPVSPSGQERSRRLHLDGDVGTQQSYSPNPSSYS SGHHGVGVEEDVHFNPDVFTYSAASKETCARHHGRCSPHAFCTDYATGVCCHCQATYYGNGRQCLPEGAV HRLNGKVSGSLMVGRMSVSFQDVDLHAYIVGSDGRAYTAITGVPQPAGRALLPLLPLGGLFAWLFALEDP GSENGFSITGAEFTQSLEVTFYPGGETVRVTQTAEGLGPDNYLSLKTHIQGQVPFLPENVTVHITPYKEL YHYSSSVVTSSAQREYVLAAGTANQTLSYRLRQNITFSGCPHTRLPAQQRLSVARAFALYDGHEHVLRYA LAARIGSAPDDAENPLVNPCHDGTHRCEAPARCQPGTGMEYTCECVAGYRRDGWGCRDVDECAEGLSQCG PFAICLNAPGSYRCECRSGYQPAGDGQMCVPLVPATDPCEDGSHPCAPPDRARCLSHAGGHPTCECLPGY AGDGIYCSDVDECAENPCHPAATCYNTPGSFSCQCPPGYEGDGFQCVHAAGSTQRLSPCQHEQLYPREVP SGPSPVGDRHMPQCDEEGGYRPLQCHSSTGHCWCVDTAGQEIAGTRTAPGSTPPRCGNPESTQRLTPCQH ERLYPRGVPPGPSPVGDRHVPQCDEDGGYRPLQCHSSTGHCWCVDAAGQEIAGTRTAPGSTPPRCGNPEP TERPRSMCERWRQSLLEHYGGSPRRDQYVPQCEAGGEFTPLQCHGDSGYCWCVDESGREIPGTRSEPGST PPCLPSVAPPSVRPSPRPDVSPPATGTFLLYAQGQQIGYLPLNGTRLQKEAAKTLLSLHGSIVVGIGYDC REKTIYWTDVAGRTISRASLEPGAEPETIISSGLISPEGLAVDHLRRAIFWTDSGLDKIERARLDGSERQ VLFDTELVNPRAIAVDPVRGNLYWTDWNREAPKIETSTVNGANRRVLVNRDIGLPNGLTFDPFSKLLCWA DAGTKHLECTFPDGTGRRIIQNNLNYPFSIISYANHFYHTDWRRDGVIAIDKETGSFTDEYLPEQRSHLY GITAVYPYCPGARK >XP_017909832.1 PREDICTED: nidogen-2 [Capra hircus] MRADRAAGRPALPLPPLLLLLLLLLSRAAALHPSELFPYGQSRGDQLLQEGDDESSAAVKLTLSLRFYDA QFSDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLYRQDTSPAVLGLAANYV RTGFPLSGAHFTPTHAFLATWEQVGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGT RPKESYNVQLQLPARVGFCRGEVDDLNRQGPYFSLTSTEQSVKNLYQHSNLGIPGVWAFHIGSTSPLDNV RPATVGGVLSKARPWAPLGQSFSPAVALEDDYTQDTLDEYDENEEEIEYPPSEPAEASNGHSAIDVSLRG RISAPDSDLASPVPRSASRGGPETEASPLDPHAEERRPQGETNAPDLKQRVESSQQPGTRVPAPPETEGE SPAPPREAPPPSLEGGAGPADQDALPAHPGGEAALPNYPGPDHAPHLGHRRQVVGVEDDISSNTEVFTYN AANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTD VDLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDAEVTFL PGEERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYADSAVTSTSTRTYSLMSGA INQTQSYRIHQNITYQVCRHAPRHWAVPVTQQLNVDRVFALYSDEEKVLRFAVTNQIGPVEGDSEPTPVN PCYDGSHTCATTARCHPATGVDYTCECASGYQGDGRSCVDVNECATGFHRCGPNSVCVNLLGSYRCECRS GYEFADDRHTCISITPPPNPCENGRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTDVDECSENRC HPLATCSNTPGSFSCRCQPGYYGDGFQCTPEPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHF TPLQCHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTIRPTPRPDVTPPPVGTFLLYAQGQQIG HLPLNGTRLQKDTAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPEMVINSGLISPE GLAIDHFRRTMYWTDSGLDKIERARLDGSERRVLFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSS LDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECIFPDGTGRRVIQNNLNYPFNIVSYADHFY HTDWRRDGVIAVNRDTGQFTDEYLPEQRSHLYGITAVYPYCPGRK >XP_014375969.1 nidogen-2 [Alligator sinensis] MTDVNKTLGTRRRAVLSRAAGYIRAGFPSTAFAPTRAVVATWEDVGAYEEVSRDAEPSRQRNTFQAVLAY DHADAYALFLYPDDGIQFFGTRPKESYHIQLELPARVGFSRGETDPRRENLHYSVASSEQGLKNLYQSSN VLTPGVWVFHIGSASPLENIVPAGAARQLLGGALPTGPESASHHATAEHDYPDGAFAIFSYDENEEDNEE FPFVEPTEVVAEDYDELGISLHTDINLQDRVQEGLEFASKLPMPASSHLPSSPEARPVPSQEPSSLETDE DLLELVSVESPTYRQREDVQPYPDGGAIPAETDVHLGYPEGEVVLQSYPDSPLPFPRGRHIVGVDEDISF NTDVFTYSAASQETCEQHHGLCSPHAFCTDYATGFCCHCQTKFYGNGRHCLPEGAAHRLNGKVSGNLLVG RTPVHFADVDLHAYVVGNDGRAYTAISRIPQLAARALMPLTPIGGLFGWLFALEKPGYENGFSITGAEFT HSLEATFYPGEETVHITQTAEGLGLENYLSLRTRIQGRVPYIPENFTVHIAPYKELYYYSSSAVTSTSHR EYSLLFGHHNQTLSYRLHQNVTFRDCPHARARRTMPATQQLSVERVFALYNEEEQVLRYAVTNQIGSAEG DSDTAVVNPCYDGTHVCDTTARCQPGAGLQYSCECTAGYCGDGQDCMDIDECAEGESRCGPFSVCLNSLG SYRCECQHGYRLTDDRRTCVLAAPPPDPCAAGRHSCAAADQARCIPRGGGAFSCECLPGYTGDGHNCSDV NECTQGRCHPAATCLNTPGSFSCQCRPGYDGDGFQCTPANLQRLTPCEHERLYSQPEPGHHIPVCDDQGN YHPLQCHSSTGFCWCVDEAGQEITGTRTPPSSTPPRCGEPEPTVRPQTMCERWRQSLLDHYGGRPREDQY VPQCDTAGSFSPLQCHGNSGFCWCVDEHGREIHGTRSEPGTAPPCLPSVAPPTVQPSPRPDVSPPAAGTF LLYAQGHQIGYLPLNGTRLQKEAAKTLLALHGSIVVGIDYDCRGKMVYWTDVAGRTVNRASLEPGAEPET VINSGLMSPEGLVVDHLRRAMFWTDSGLDKIERANLDGSQRRALFSTDLVNPRAITVDPIRGNLYWTDWN REAPKIETSTVEGANRRILVNEDIGLPNGLTFDPFSKLLCWADAGTKKLECMFPDGTGRHVVQNNLNYPF SIVSYANHFYHTDWRRDGVIAVNKDTGSLTEEYLPEQRSHLYGITAVYPYCPGVRK >XP_015807982.1 PREDICTED: nidogen-2 isoform X1 [Nothobranchius furzeri] MRPVTNQVEPNILDPAPAPLLTSSGAAGPSSDCSPPFLLLPCVLVPRTQSSLLGVDMDGGSVLAAALLYW SCGVCVVSALHRTDLVSYGALSGDLILAEGDDETSRVLTLPRPLYFYDTPFHQLYVATNGIISAQDLPME KQYVDDGFPTDFPVVAPFLADIDTSGGRGHIYYRVTETPSVLNRVAQEVRRGFPDAKFAPTHAVVATWEN VAAYEDQTQGTELSNKVNTFQAVIGYDETDSYTLFLYPEDGLNFFGTQPKELYNVKIELPARVGFSRGEV TFFIFSRSEGPFYSVTTDEKSVKRLSQVGNTGIPGVWLFHTGNRHSFENIIPAAIGGLLSTLPPEGHALS PDTTTPEYGDYPDNTFESESPEEVDGYTATGKDLEFQPVPDGGDSGSLQPGSPGSTPPSSEDSDHQVTYN GEEGEEGQYVPPNHPERRAQQLQEQKPQLPLEVVEVNPSPENEPPLSPGGYVVSVDEEDVDFDTGVIQYT TENKETCARFQQQCSQNAICSDYATGFCCHCRPGFYGNGRQCLPDGAPQRVSGKVSGTVTVGSFPIVLDN IDLHAYIVVGDGRAYTAISQVPEPVGWALMPVSPVGELFGWLFALELPNSQAGFKTTGAEFTRHAEVLFN PGNQRLSIIQTGSGLDEHNHLRVETIVSGHVPLLPPGAEVTVQPFKETYQYYPSVITSSSVREFVVVSAE RGSQSYTFHLKQNITYRDCRHDNRATPETLQITMERVFVMYVKEERILRYAITNKISPVGAGSDDELLNP CYVGNHDCDTTAQCIPLEGQAFKCQCATGYTGDGHNCYDIDECAEGSDLCGDHSQCLNLPGSHRCQCWEG FEMAFDGRNCVDIDECSSSPCHINARCINDLGSFRCHCQPGFHGDGFYCALQEGRPKSQCEQHRDSLQSG GHGDGAHIPQCDSDGRYRSLQCHGSNGYCWCVDDRGQERPGTRTSPGTTPKDCDKPDDPQRPKTHCEHHR DSIQTTSPDGRPLLGAYAPQCDEHGHYKPQQCLGSTGYCWCVDSRGQERPGTRTAPGTPHVDCDKPDRPK THCERHRDSVQTTSPDGHPLLGAYVPQCDEHGHYQPQQCHGSTGHCWCVDDKGQERPGTRTPPGTPHVDC RRPEGPKTHCELHRDRVQHTGPDGHPIVGAHIPQCDEHGHYQPQQCHGSTGHCWCVDDRGQERPGTRTPP GTPHVDCRRPERPKTHCELHRDRVQHTGPDGHPIVGAHIPQCDEHGHYQPQQCHGSTGHCWCVDDKGQER PGTRTPPGTPHVDCRRPDDPQRPKTHCEHHRDSVQTTSPDGHPLVGAYVPQCDEHGHYKAQQCHGSTGHC WCVDDKGQERPGTRTPPGTPHVDCRRPKRPKTHCELHRDRVQQTGPDGHPIVGAHIPQCDEHGHYQPQQC HGSTGHCWCVDDKGQERPGTRTSPGTPHVDCRRPERPKTHCELHRDRVQHTGPDGHPIVGAHIPQCDEHG HYQPQQCHGSTGHCWCVDDKGQERPGTRTPPGTPHVDCRRPERPKTHCELHRDRVQHTGPDGHPIVGAHI PQCDEHGHYQPQQCHGSTGHCWCVDDKGQERPGTRTPPGTPHVDCRRPEHPKTHCEQHRDRVQVTSPGGH PIEGTYVPQCDEHGHYQPQQCHGSTGQCWCVDDRGQERPGTRTPPGTPRVDCSRSERPKTSCEQHKERAE ATSSEGYPIAGAYVPQCDAKGQYIPLQCFGSTGHCWCVDPSGQERPGTRTPPGTPPKDCAKPGRPKTPCE QHRDRVQATTREGYPVVGGYEPRCDAEGQYLPQQCHGSNGHCWCVDSSGQERPGTRTPPDTPPKDCSKPA STSRPESVCERWRASLMEHYGGKPDPQQYLPQCEPAGEFSPVQCYGHTTYCWCVDENGREVPGTRSHDVV KPACLPSVTPPTARPLPRPNVTPPPNADVTLLYAQGQKIGALPLNGTRLDSSRSRTLLTLHGSIVVGIAY DCKENQVYWTDLSARTINRASMVSGAEPEILINSNLVSPEGLAVDVKRRLMFWVDSSPDVIESANLDGSR RRILFDTDLVNPRAIIVVSSTGTLYWTDWNREAPKIESSSVDGLNRRVVVSDGVGLPNALTYDSSSGQVC WADAGTKRLECISPNGSGRRVIHPTLNYPFSMVYYRNHFYYTDWRRDGVIAVSKDSSKFTDEYLPEQRSH LYGVTIATTYCLPGNH >XP_030857550.1 nidogen-2 isoform X1 [Gorilla gorilla gorilla] MEGDRVAGRPVLSSLPVLLLLPLLMSRAAALHPDELFPHGESWGDQLLQEGDDESSAVVKLENPLHFYEA RFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRGRVLYREDTSPAVLGLAARYV LAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTR PKESYNVQLQLPARVGFCRGEADDLKSEGPYFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVR PAAVGDLSAAHSSVPLGRSFSHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKV DTKPLEGRISPPDSHLSSPLHPTPTYWPFYPETESSTLDPHTKEGTSLGEVEGPDLKGQVEPWDERGTRS PAPPEVDRDSLAPSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEIVLRNYPASGHTTPLSRGTY EVGLEDNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGSGKHCLPEGAPHRVN GKVSGHLHVGLTPVHFTDVDLHAYIVGNDGRAYTAISDIPQPAAQALLPLTPIGGLFGWLFALEKPGSEN GFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVPANFTAHISPYKELYHYS DSTVTSTSSRDYSLTFGAINQTWSYRIHQNVTYQVCRHAPRRPSFPTTQQLNVDRVFALYNDEERVLRFA VTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCG PNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGY AGDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQQRHAQAQYAY PGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTICERWR ENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMV RPTPRPDVTPPSVGTFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAG RTISRASLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRA IAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLP DGTGRRVIQNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYLPEQRSHLYGITAVYPYCPTG KKYALEKYALGCSFKLAG >XP_030265795.1 nidogen-2 isoform X1 [Sparus aurata] MERGRLLAVCVLCWSCSVRVVTAIQRADMFPYGSLSGDMILAEGDDETSRVLSLPRPVYFYDSLFSQLYV ATNGIVSAQDLPMEKQYVDDGFPTDFPVVAPFLADIDTSGGRGQIYYRVTETPSVLNRVAQEVHRGFPDA KFTPTHVVVATWENVAAYEEPTRTSGPSNKFNTFQAVIGYDEVDSYVLFLYPEGGLNFFGTRPKESYNVE IELPARVGFSRGEVTYLIFSRTEGPHYSVTSDEQSVKNLYQVGNTGIPGVWLFHTGNRYSFDNIVPASVG GLLATPPTRGHGLSLDTTTPDYPEFEEYPDNTFDPDSQDEEDDYPLTGGDAEFQPAPASDHSEAPQPASP DAPSSPSEDVPHGSQPSNRQYAPPNPPEAAPEEQQPQVPLEVVDVYPPHRNEPPLSPGGHVVSVDEDDVD FDTGVIQYTTENKETCARFQQQCSQNAFCSDYATGYCCHCRPGFYGNGRHCLPEGAPQRVSGKVSGTVTV GSTPVDLNNIDLHAYIVVGDGRAYTAISEVPEPVGWALMPVAPIGELFGWLFALELPNSQAGFKITGAEF TRRAEVIFYPGNQRLSIIQTGRGLDDHNHLTVDTVLSGSVPFLPPGAEVTMDPFKETYQYYPSVATSTSV REYSVVSADRGSESFSFQLKQNITYRDCRHDSSTTALETLQITMERVFVMYVKEERILRYAITNKISPVG VEPTGPELVNPCYAGTHDCDTTAQCIPQEGQAFRCQCATGYRGDGRNCYDIDECAEGLSTCGAHAQCMNL PGSHRCQCQSGFEFGFDGRTCVDVDECSSSPCHVDARCINGLGSFQCQCQAGFYGDGFYCSQQEGQTVRP KSHCEQHRDSLQSGGDGRPSVGAFIPQCDSDGRYRLLQCHGSTGHCWCVDSRGQERAGTRTPPGTAPKDC DRPDEPERPKTHCEHYRDSVQTTSPEGYPITGAYVPQCDANGQYIPLQCHGSSGHCWCVDSNGQERVGTR TAPGTTPIDCDKPEEQERVKTQCEHHRDSVQTTSPEGYPIVGAYVPQCDANGQYRSLQCHGSTGHCWCVD TRGQERAGTRTPPGTATKDCDRPDEPERPKTHCEHHRESVQTTGPEGYPIVGAYVPQCDANGLYTPLQCH GSSGHCWCMDSRGQERAGTRTLPGAPPTDCDKPDEPERPKTHCEHHRDSVETTGPEGYPIVGAYVPQCDA NGQYRSLQCHGSSGHCWCVDSRGQERAGTRTPPGTAPKDCDKPDEPERPKTHCEHHRDSAQTTSPEGYPI PGAFVPQCDANGQYASQQCHGSSGHCWCVDRTGQERAGTRTPPGTAPIDCNKQDEPEHPKTHCEQHRERA QATSSDGYPIVGAYVPQCDANGQYRPLQCHSSSGHCWCVDRTGQERAGTRTPPGTATKDCDRPDEPEHPK THCEHHRERAQATSSDGYPIVGAYVPQCDANGQYRPLQCHSSSGHCWCVDRKGQERAGTRTPPGTATKDC DRPDEPEHPKTHCEQHRERAQATSSDGYPIVGAYVPQCDANGQYRPLQCHSSSGHCWCVDRTGKERAGTR TPPGTATKDCDRPDEPEHPKTHCEHHRERAQATSSDGYPIVGAYVPQCDANGQYTPLQCHSSSGHCWCVD RTGQERAGTRTPPGTAPKDCDRPDEPERPKTQCEQHRDSVQTTSPEGYPLFGAFVPQCDPNGQYSAQQCH SSTGHCWCVDGRGEERAGTRTTAGIPPVNCDESVPVVPTQRLESVCERWRSSLIEHYGGKPEPQQYLPQC EPDGQFSPVQCYGETTYCWCVDQDGREVPGTRSHDVVKPACLPSAAPPTVRPLPRPDVTPPTNADITLLY AQGQKIGALPLNGTRLDATRAKTLLTLHGSIVVGIAYDCRENRVYWTDLSARTINRASMAPGAEPEILIN TNLVSPEGLAVDVKRRLIFWVDSNPDMIESANLDGSGRRTLFDTDLVNPRAIIVVSSSGTLFWTDWNREA PKIESSSVDGQNRRVVVSDGVGLPNALTFDSSSGQVCWADAGTKRLECVSPDGSGRRVIHSSLNYPFSMV YYRNHFYYTDWRRDGVIVVSKESSQFTDEYLPDQRSHLYGIAIATSQCLSGTH >XP_040188888.1 nidogen-2 [Rana temporaria] MVSRVLRILHWHCLLLGFSAAISRQELFPYGESRGDRLLPDGDDETSEVVTLTQPILFYEADFKELYVGT NGIISTQDFPRETQYVDDGFPTDFPVIAPFLSDIDTSNGKGKIYYRQDNSPDILSTVARQVDRGFPQAAF SPTNVFMVTWDNVGAYEEVTRHAEPSNKLNTFQAVLAYDDSDTYAIFLYPEHGLQFFGTRPKESYNVHLD LPARVGFSRGDSEMLKKEAPFYSVTSSEQSVKNLYQTSNVGVPGVWVFHIGSLSEIDNVIPAKVPHHHPQ QRFVPLINSHNDFPEQQQQQQLENQFNGENNYEDNYEDEDYPAGQTTEAPTTDSAVLNPDRTHDFIDAED HATLYTPNNPLPPSQEEPSWTPYNPDEPLVEPEIQRSESRVLGNIPSYETQEEPSESVSEDFNNVTPNPV DPQRSDVYRSNRFYGNEEVGGLDTDVLTFNPVSRETCDRKPGYCSPYAFCTDYATGFCCHCQDSYYGNGV HCLPKGAPHRVNGKVSGNLLVGQRPVTFDGIDMHAYIVVNDGRAYTAISQVPEPASWSLTPLTAIGGLFG WLFALEKPGHQNGFSITGAKFVHNLEAVFSPGEEVIHVTQTADGFDSDNYIHVRTTIKGKIPYIPETSTV QIAPYYEIYQHSGSVVTSTAYREYTVTSQSGDVQKFSYRLKQNITYQECGHAQKYPPTAQKLSVDRVFAM HNKDEKVLRFAITSHIGSLHDSSQEPTQGNPCFDGTHQCDTRAQCQPATGLNYSCVCASGYRGDGRDCTD YDECEDQLDNCGQNTRCVNLPGSFRCECVPGYVFSADGQNCILGSSFGNPCEDGTHSCDLTTSQCVPRGD GVFTCECFPGYTRSGQSCIDVDECAERRCHPDATCANVPGSFSCRCNPGFTGDGFQCTQAPEEPRPSTPC LEKRHAAQPRGPRPPLIGAFLPECDEEGNYVPLQCHGSTGHCWCVDRNGNEIEGTRRPAGSGRPQCGIPE PTQRPQTMCERWKQSLVDHYGGSPSAEHYIPQCDAYGEFSPLQCHGNSGYCWCVDKDGREIEGSRTQPGM TPACLPSVAPPTVRPTPRPDVTPPTSGTYLLYAQGQQIGYLPLDGVKFRKDKARTLLALHGSIVVGIDYD CQEKKVYWTDVSGRTISRAGLEPGAEPEVLISTDLMSPEGLAIDYLRKTMFWTDSGTDKIESARLDGTFR KTLFDTNLVNPRAITVDAVRGNLYWTDWNREAPKIETSYVDGSNRRILVNDNIGLPNGLTFDPFSKQICW ADAGTKKLECILSDGSGRRVIQSNLNYPFSVVGFANHFYHTDWRRDGVISINKENGQITEEYLPEQRSHL YGITAIYPYCPSGKK >KYO47226.1 nidogen-1 [Alligator mississippiensis] MLHRCRRGGMPRLFPHGPARGDRALPPGDDEGSALPLAPLLPFYGLRLARLHVGTNGLLSGQDFPRETQYVDDDLPTDFP AIAPFLADLDTSGGRGQIYYRQDGASDVLSRAAGYIRAGFPSAAFAPTHAVVATWEDVAAYEAVSRDAEPSRQRNTFQAV LAYDHADAYALFLYPDDGIQFFGTRPKESYHIQLELPARVGFSRGETDPGRENLHYSVASSEQGLKNLYQSSNVLTPGVW VFHIGSASPLENIVPAGAGRQLLGGALPTAPESVSRHATAEHDYPDGAFAIFSYDENEEDNEEFPFVEPTEVVAEDYDEL GISLHTDINLQDRPSSLETDEDLLELVSVESPTYRQREDVQPYPDGGAVPAETDVHLGYPEGEVVLQSYPDSPLPFPRGR HIVGVDEDVSFNTDVFTYSAASQETCEQHHGLCSPHAFCTDYATGFCCHCQTKFYGNGRHCLPEGAAHRLNGKVSGNLLV GRTPVHFADVDLHAYVVGNDGRAYTAISRIPQLAARALMPLTPIGGLFGWLFALEKPGYENGFSITGAEFTHSLEATFYP GKETVHITQTAEGLGLENYLSLRTHIQGRVPYIPENFTVHIAPYKELYYYSSSAVTSMSHREYSLLFGHHNQTLSYRLHQ NVTFQDCPHARARRTMPATQQLSVERVFALYNEEEQVLRYAVTNQIGSAEGDSDTAIVNPCYDGTHVCDTTARCQPGAGL QYSCECTAGYRGDGQDCVDIDECAEGESRCGPFSVCLNSLGSYRCECQHGYHLADDRHTCVLAAPPPDPCAAGRHSCAAA DQARCIPRGGGAFSCECLPGYTGDGHNCSDVNECTQDRCHPAATCLNTPGSFSCQCRPGYDGDGFQCTPANLQRLTPCEH ERLYSQPDPGHHIPVCDDQGNYQPLQCHSSTGFCWCVDEAGQEIAGTRTPPGSTPPRCGEPEPTARPQTMCERWRQSLLD HYGGRPREDQYVPQCDAAGSFSPLQCHGNSGFCWCVDEHGREIHGTRSEPGTAPPCLPSVAPPTVQPSPRPDVSPPAVGT FLLYAQGHQIGYLPLNGTRLQKEAAKTLLALHGSIVVGIDYDCRGKMVYWTDVAGRTVNRASLEPGAEPETVINSGLMSP EGLVVDHLRRAMFWTDSGLDKIERANLDGSQRRALFSTDLVNPRAITVDPIRGNLYWTDWNREAPKIETSTVEGANRRIL VNEDIGLPNGLTFDPFSKLLCWADAGTKKLECTFPDGTGRHVVQNNLNYPFSIVSYANHFYHTDWRRDGVIAVNKDTGSL TEEYLPEQRSHLYGITAVYPYCPGARK >XP_043327612.1 nidogen-2 [Cervus canadensis] MRGDPAAGRPALPPPLLLMLLLLSRAAALHPSELFPYGQSRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNGI ISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLFRQDTSPAVLGLAASYVRAGFPLSGAHFTPTHAFLATWE QVGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGPY FSLTSTEQSVKNLYQHSNLGIPGVWAFHIGSTSSLDNVRPATVGGDLSKARPSAPLGQSFSHAVALEDDYTQDPLDDYDE NEEEIEYPPSEPAEASNGYSSVDVSLRGRISAPDSDLASPVPRSASQGGPESESSPLDPHTKERRPQGETDASDLKGQVE SSEQPGTRVPAPPETEGESPAPPEVAPPPSPEGGAGPADQDALPAHPGGEAALPNYPGPDHTPHLGHRRQVVGVEDDISS NTEVFTYNAANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDVD LHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFYPGEERVRITQTA EGLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYADSAVTSTSTRAYSLMSGAINQTRSYRIHQNITYQVCRHAP RHWAVPITQQLNVDRVFALYSDEEKVLRFAVTNQIGPVEGGSEPTPVSPCYDGSHTCATTARCHPATGVAYTCECASGYQ GDGRSCVDVDECATGFHRCGPNSVCVNLLGSYRCECRSGYEFADDRHTCILITPPPDPCEDGRHNCAPASQARCIHHGDG SFSCACLPGYAGDGHRCTDVDECSENRCHPSATCSNTPGSFSCRCQPGYYGDGFQCTPEPTQRPRTVCERWRESLLEHYG GTPRDDQYVPQCDGLGHFTPLQCHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTIRPTPRPDVTPPPVGTFLL YAQGQQIGHLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPETVINSGLISPEGL AIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVNK DIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQNNLNYPFNIVSYADHFYHTDWRRDGVIAVNRDTSQFTDE YLPEQRSHLYGITAVYPYCPGRK >KAF4017381.1 hypothetical protein G4228_009148 [Cervus hanglu yarkandensis] MLLLLSRASALHPSELFPYGQSRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNGIISTQDFPRETQYVDDDFP TDFPAIAPFLADIDTSGGRGRVLFRQDTSPAVLGLAASYVRAGFPLSGAHFTPTHAFLATWEQVGAYEEAKRGAPPSGEL NTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGPYFSLTSTEQSVKNLYQHSN LGIPGVWAFHIGSTSSLDNVRPATVGGDLSKARPSAPLGQSFSHAVALEDDYTQDPLDDYDENEEEIEYPPSEPAEASNG YSSVDVSLRGRISAPDSDLASPVPRSASQGGPESESSPLDPHTKERRPQGETDASDLKGQVESSEQPGTRVPAPPETEGE SPAPPEVAPPPSPEGGAGPADQDALPAHPGGEAALPNYPGPDHAPHLGHRRQVVGVEDDISSNTEVFTYNAANKETCEHN HERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDVDLHAYVVGNDGRAYTAISH IPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFYPGEERVRITQTAEGLDPENYLSIKTNIQGQ VPYIPANFSAHMAPYKELYHYADSAVTSTSTRTYSLMSGAINQTRSYRIHQNITYQVCRHAPRHWAVPITQQLNVDRVFA LYSDEEKVLRFAVTNQIGPVEGGSQPTPVSPCYDGSHTCATTARCHPATGVAYTCECASGYQGDGRSCVDVDECATGFHR CGPNSVCVNLLGSYRCECRSGYEFADDRHTCILITPPPDPCEDGRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCT DVDECSENRCHPSATCSNTPGSFSCRCQPGYYGDGFQCTPEPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDGLGHF TPLQCHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTIRPTPRPDVTPPPVGTFLLYAQGQQIGHLPLNGTRLQ KDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPETVINSGLISPEGLAIDHFRRTMYWTDSGLDK IERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLC WADAGTKKLECILPDGTGRRVIQNNLNYPFNIVSYADHFYHTDWRRDGVIAVNRDTSQFTDEYLPEQRSHLYGITAVYPY CPGKQLLRQRLGISRVEEDRSSS >KAB0344697.1 hypothetical protein FD754_021623 [Muntiacus muntjak] MRGDPAAGRPALPPPLLLLLLLSRAAALHPSELFPYGQSRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNGII STQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLYRQDTSPAVLGLAASYVRAGFPLSSVHFTPTHAFLATWEQ VGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGPYF SLTSTEQSVKNLYQHSNLGIPGVWAFHIGSTSPLDNIRPATVGGDLSKARPSAPLGQSFSHAVALEGDYTQDPLDDYDEI EEEIEYPPSEPAEASNGHSSVDVSLRDRISAPDSDLASPVPPSASQGGPETESSPLDPHTKERRPQGETDASDLKGRVES SEQPGTRVPTPAETEGDLPAPPGEAPPPSPEGGAGPVDQDALPAHPGGEAALPNYPGPDHAPHLGHRRQVVGVEDDISSN TEVFTYNAANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDVDL HAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFYPGEERARITQTAE GLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYADSAVTSTSTRTYSLMSGAINQTRSYRIHQNITYQVCRHAPR HWAVPITQQLNVDRVFALYSDEEKVLRFAVTNQIGPVEDVNECATGFHRCGPNSVCVNLLGSYRCECRSGYEFADDRHTC ILITPPPDPCEDGRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTDVDECSENRCHPSATCSNTPGSFSCRCQPGY YGDGFQCTPEPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDGLGHFTPLQCHGKSDFCWCVDQDGREVQGTRSQPGI TPACIPTVAPPTFRPTPRPDVTPPPVGTFLLYAQGQQIGHLPLNGTRLQKDVAKTLLSLHGSIVVGIDYDCRERMVYWTD VAGRTISRASLEPGAEPETVINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQ GNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQNNLNYPFN IVSYADHFYHTDWRRDGVIAVNRDTGQFTDEYLPEQRSHLYGITAVYPYCPGRK >KAB0375038.1 hypothetical protein FD755_013530 [Muntiacus reevesi] MRGDPAAGRPALPPPLLLLLLLLLSRAAALHPSELFPYGQSRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNG IISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLYRQDTSPAVLGLAASYVRAGFPLSGAHFTPTHAFLATW EQVGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGP YFSLTSTEQSVKNLYQHSNLGIPGVWAFHIGSTSSLDNVRPATVGGDLSKARPLAPLGQSFSHAVALEGDYTQDPLDDYD EIEEEIEYPPSEPAEASNGHSSVDVSLRDRISAPDSDLASPVPPSASRGGPETESSRLDPHTKERRPQGETDASDLKGRV ESSEQPGTRVPTPPETEGDLPAPPGEALPPSPEGGAGPADQDALPAHPGGEAALPNYPGPDHAPHLGHRRQVVGVEDDIS SNTEVFTYNAANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDV DLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFYPGEERARITQT AEGLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYTDSAVTSTSTRTYSLMSGAINQTRSYRIHQNITYQVCRHA PRHWAVPITQQLNVDRVFALYSDEEKVLRFAVTNQIGPVEVITPPPDPCEDGRHNCAPASQAQCIHHGDGSFSCACLPGY AGDGHRCTDVDECSENRCHPSATCSNTPGSFSCRCQPGYYGDGFQCTPEPTQRPRTVCERWRESLLEHYGGTPRDDQYVP QCDGLGHFTPLQCHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTFRPTPRPDVTPPPVGTFLLYAQGQQIGHL PLNGTRLQKDVAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPETVINSGLISPEGLAIDHFRRTMY WTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTF DPFSKLLCWADAGTKKLECILPDGTGRRVIQNNLNYPFNIVSYADHFYHTDWRRDGVIAVNRDTGQFTDEYLPEQRSHLY GITAVYPYCPGRK >XP_020724590.1 nidogen-2-like [Odocoileus virginianus texanus] MRGDPAAGRPALPPPLLLMLLLLLSRAAALHPSELFPYGQSRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNG IISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLYRQDTSPEVLGLAASYVRAGFPLSGAHFTPTHAFLATW EQVGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGP YFSLTSTEQSVKNLYQHSNLGIPGVWAFHIGSTSPLDNVRPATIGGDLSKARPSAPLGQSFSHAVALEDDYTQDPLDDYD ENEEEIEYPPSEPAEASNGHSSVDVSLRGRISAPDSDLASPVPRSASRGGPETESSPLDPHTKERRPQGETDASDLKGRV ESSEQPGTRVPAPPETEGDSPAPPGEAPPPSPEGGAGPADQDALPAHPGGEAALPNYPGPDHAPHLGHRRQVVGVEDDIS SNTEVFTYNAANKETCEHNHERCSRHAFCTDYAAGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDV DLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFYPGEERVRITQT AEGLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYADSAVTSTSTRTYSLMSGATNQTRSYRIHQNITYQVCRHA PRHWAVPITQQLNVDRVFALYSDEEKVLRFAVTNQIGPVEDKVVSMSKI >XP_018084587.1 nidogen 2 L homeolog isoform X1 [Xenopus laevis] MHIPTAIPAGTAATARSKSLFPSNQCARREEPGVILRLGLSAPCSSVYWSATATPTLGSALGSDVEAPGSELLSTLGRGA YPLALNVGLASIRIVAMWDRTVRLLLPLHCLLAFSAAISRRELFPYGELKGDVLLQEGDDETSEVVKLSQPLLFYEAQFS NLYVGTNGIISTQDFPRETQYVDDGFPTDFPVIAPFLSDIDTSNGKGKIFYRQDNSEPVLNHAAREIQRGFPEATFIPNH AFLVTWENVGTYEEVTRHSASSDRRNTFQAVLAYDHSDAYAIFLYPEDGLQFFGTRPKESYNVHIELPARVGFSRSEAGP YYSVTSNEQSVKNLYQTGNVGVPGIWVFHIGSIWELDNVIPAKFFGAPANEQSLENSHTSFPEHRLFENHENEDSIDYPE SFYEESEDELEDNTSDATPTHETHQEGDSNTGNQGYLDIDDQASKLTHAEDEQKATSSAVLSSSHQNPNWTPYTPSESET DRDGPLQEPQIQTGENLDLTREDTLLTDDLPSHNAPDSIPSNSEDLPIYPESAVLVGSHPEQENNFERGRQTDADPGLQT DVFSFKPAGKETCERNHGRCSRFAFCADYSTGFCCHCQEDYYGNGVHCLPRGAPHRVNGKVSGNILVGQTPVNFIDADLH AYIVANDGRAYTAISNVPDPASWSLTPLAPIGGLFGWLFALEKPGFQNGFSFTGAKFVHNIDVTFYPGEEAIHITQTANG FDSEGYMNVKTAIQGKIPYIPETSTIKLSPYTELYQYSGSVVTSTAYREYTVLSESNEEQKLSYRLRQNVTYQECSHSQK QSVSAQKLYVDRVFALYNKEEKVLRYAITNYIGSVHDSTGEEDLKVNPCYDGTHLCDTRAKCQPGSGLEYICVCASGYQG DGRDCTDVNECEVGFTRCGQNTVCVNLQGSYRCECASGFTLSGDEHNCILASSINPCEDGRHMCNRDTSRCVPHGDGVYT CQCFPGFIMSGEKCVDVDECTEHRCHPDASCTNTLGSFSCRCNSGYEGDGFQCTQILDPEPLRTPCLEKRQQLLGQLHPR GPRPVVGQFVPECDAEGNYVPLQCHGSTGHCWCVDKLGEEVAETRTPPGRPSPNCGDKGPEPLRTPCLEKRQQLLGQLHP RGSRPVVGQFVPECDAEGNYVPLQCHGSTGHCWCVDKLGEEIAGTRTQPGRTSPNCADKGPEPLRTPCLEKRQQLLGQLH SRGPHPIVGQFVPECDVEGNYVPLQCHGSTGHCWCVDKLGEEVAGTRTPPGRPSPNCGDTAEPTQRPQTVCERWKQSLIE HYGGKPSGEHYVPQCDQYGDFSPLQCHGNSGYCWCVDKEGREIEGSRTEPGMTPACIPTVAPPTMHPTPRPDVTPPATGT FLLYAQGQQIGYLPLNGTRLHKDKARTLLSLHGSIVVGIDYDCHEKMVYWTDVAGRTINRASLEPGAEAEIIINTGLMST EGLAIDYLRRTLFWTDSGLDKIESSRLDGTERKILFDTQLVNPRAITVDAVRGNLYWTDWNREAPKIESSFVDGSNRRIL VNDNIGLPNGLTFDPFSKQVCWADAGTKKLECILSDGTGRRVIQSNLNYPFSVVAYANHFYHTDWRRDGVISIKKDTGHI VEEYLPEQRSHLYGITAVYPYCPSGRK >OWK09497.1 NID2 [Cervus elaphus hippelaphus] MGATRVPPQLVAIRRQVWPTPASVHLDVDECATGFHRCGPNSVCVNLLGSYRCECRSGYEFADDRHTCILITPPPDPCED GRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTDVDECSENRCHPSATCSNTPGSFSCRCQPGYYGDGFQCTPEPT QRPRTVCERWRESLLEHYGGTPRDDQYVPQCEGLGHFTPLQCHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPT IRPTPRPDVTPPPVGTFLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLE PGAEPETVINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREA PKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQNNLNYPFNIVSYADHFYHTD WRRDGVIAVNRDTSQFTDEYLPEQRSHLYGITAVYPYCPGKQLLRQRLGISRVEEHRSSS >XP_791550.3 nidogen-1 [Strongylocentrotus purpuratus] MKLLLGIFAVLIAVVNCLPRDQFFPFGEGTTDKKLNRRSKKPLTLSFREPFTFLGEEQSLLYIVRDGYVSFSSGARGSKI APFHTKLKLIRGQSSVWYRTTVSSNEEDEIINLIQRNFRSRGSTDFTTFSPSSFVIVTWENMAVRNSDHEVIGTVTFQLI LVADAMHSFAFFLYDENNDYPRPDRIGSNIDAGFTSGKAHNQWEFEMVYTTEDNKAATLFEAMRDSNVGMNGMWAYKIDG RMDGNIIPAVAYVPVESLPQNDEPPQDAVNIQLDNTFDVVLDFENQCTRETCSVDGRCVPYPTGHCCACNEGFMGNGIHC LSINDNGRMNGRVNGTINGVTIPDEVYLHTFIMGGGGRTFTAISPVPSSIAYSMQILLPIGELMGWMFAEPAAKGINGFM QTGGDLLYSANIRFENGDEVSIIQRYTGVDESEEGGGVIGGYVTIDGNVPNLSPGTSVSVDRHSEVYTKYRPGYVYSSEQ RSLDADGQTIRFSIEQTITYQECEADDINTDASLTAMRMNTTYAYSIFEPQGDILRYAMITNVGPDIGVPTDACQDNNCG TNAECFPQANTFTCRCRAGYTGNGYTCTESPSDPCDNNDCDRNANCYPAGNSYTCQCNTGFNGDGRVCVADQASDPCDTN DCSLYAYCYPTNDGQSFYCQCATGFTGDGRNCEREQRGNACDNNNCSPYAYCRPRGDTDFTCECAPGYVGDGYNCEEESQ DPCLNNRCHPYADCSPVPGGYTCSCRSGYQGDGYLCEEADQLVNLCSDCGRDADCLPEGRGYRCICRAGFNGDGLTCEDV DECLEGADIACDANARCQNNRGSYTCRCNAGYRGDGFTCEALPEADGSLVFGQGMSVMNLPRDGSAGNKVYMKSRQTVVG LGYDCRHEYVYWTDISGRAIMKASLDGRDVSVVVNTSLSSPEGVAVDHLSRNLYWTDSGFDRIEVANLDGTNRHVLFDTD LVNPRAIVIDPVGGYLYWVDWDRSYPRIEVSGMDGSGRAVFLDEDLIMPNGLTIDLVSQLLCWADAGTQKVECMNLDGDP LSRYPVYRPAQYPFGLASLGNNLYWTDWQTSNIQFINKNGGEVQSLALPRGGNGRTYGIAAVTQCTDGNNRCAYENGGCR NLCLPAPGVRATCVCPNALAPNDIPCN >XP_038046990.1 fibropellin-1-like isoform X23 [Patiria miniata] MAWLFALPSGKGYNGFMLTGGKFRQTLNITFSTGEQMLITQDFQGVDENGYIRVIADWNGNIPEITPSDYVFVDDHKEEY VRHRLGVIHTFAKRSLQVNDDTISYTMDQTIEYDECSADEADTEYILNFMRVSMTETYLIYEASEEILRFSMIGKVTPAS EQIDDPCVSNNCDRNAQCLPAGDSGFRCKCNEGYEGNGQTCTGSNPCAQNSCDVNGYCIPQADRYTCACNAGYQGDGYTC SVDRCASSRCDPNARCVETTQGYECYCNAGFTGDGFRCQVSNPCDNNACDANAYCVPTQSGYQCYCNDGYSGDGYNCQEE ESDHCANNNCDPNARCVSAVFGYQCFCDPGYRGDGYTCQANNATDPCANHTCDTNARCVASAQDTYECYCFEGYTGDGFT CEVDPANPCASNTCDANARCVASAQDAYECSCLEGYTGDGFTCEVNPANPCAINTCDANARCVASAQDAYECSCLEGYTG DGFTCEVNPTNPCAINTCDANARCVASAQDAYECSCLEGYTGDGFTCEVNPANPCAINTCDVNARCVATAQDAYECSCLE GYTGDGFTCEVAVDPANPCAINTCDANARCVASAQDAYECSCLEGYTGDGFTCNATDPCASNVCDPNARCVAFSPAIYEC SCLEGYTGDGLTCEANTTDPCVNNACDMNARCVASAQDAYECSCLEGYSGDGFTCMANTTDPCVNNACDTNARCVASAQD AYECYCFEGYTGDGFTCEAEQINFCANNNCDRNARCVPTQTGYQCFCNQGYEGDGYSCRATQIDRCANNACDVNAYCVST ASAYNCYCNDGFSGDGFVCREIVDPCANNNCDVNARCVPSQSGYQCYCNQGFNGDGFTCQAVSVDLCYNNRCDFNAECSP AQDGGYSCTCNQGYEGDGFTCRNTLVNLCSACDASAQCIPEGRGFRCVCRSGFQGNGLVCEDIDECSQSGAACHRYATCY NVRGSFSCYCQPGYEGDGFSCQEVTQPELDDGALIYARGMAVMRVPLNANKPGNKIVFRSGQTIVGLGYDCQEEYIYWTD VSGRTISRAKADGSSTEVLISRGLSSPEGVAVDWLSRNMYWTDSGYDRIEVANLDGSNRRVLLKTDMINPRAIAVDPIGG LMYWTDWNRDAPKIERANMDGSERSVLVDSNLGLPNGLSLDYTTSQICWTDAGTKRIECMNMNGDPLTRFTVLPNSNYPF SIASYGFKLYWSDWETKSIQTISKTGGSESTDLKLPRGGNGRIYSVTAITSCPSTSNACSSNNGGCSSLCLPTQGGQRYC ACPTNLEGNEVPCV >XP_026296012.1 LOW QUALITY PROTEIN: nidogen-2 [Apis mellifera] MVENNQSRESSPILACEEASVGAMEGGPRHEIIGGTGRESRETTVFHAFERRAAERTSGQRRLGGGKRELVVAFVAVSID SSVKAVRERMTRRACRLSVSWPALVLATLVIAPFAVALNKNDLYPYSIPGTSILQTDPNGLLLSAETILKTPIAFYDQIF NSIFVNGNGVLSFARAMHRFFNIAFPLDDPVIAPLYTHVDTRGSGRVYYGETDAPEILARAGGMVRSAFTDAADFVPTHA FLATWVDVGYYNGKSDKVNTYQVAISSNGTHSYVELLYPDDGIQWIQGESHPNGLPDAKAQAGLMSEGRMYTLRGSGTDQ IQNVDKWSNVNRPGQWVFQVGPISDEEDIKVPDNVEDSSATNEVANCRTGATACHSKATCVDYEVGFCCHCKQGFFGNGK SCQPNDVPLRVNGRISGTINGVEFLARDLQCYVQTKDGRTYTALSRVPEEIGASFQLLGNLGGVIGWLFAKPIGETKNGY ELTGGLFNHTAELTFPSTGDKVTIRSNYLGLDVFGQLKMQAQIEGTLPQLGRDTGLDYGDYDELYTRVQTGVIRSRAERV CKLAEGVESRELDFVQDETIYYNECPYLTVEPEDDTTRLKFFRGVTTYEATEGIIRFAVNTKVAPLEEEDPCIQGRETCG DHSYCVVDGDSFKCVCNPGYQYLYEEDGSAICIDVNECTAGKHMCSPDAQCINQEGSHTCQCRPGFSGDGRTCDKLPSCE DTRCDNYEQCVMIEGAPNCICLPGFEDTEQGCYPATQRAPCDVEDNCSPNGFCNIDAEKQKYVCVCLPGFIGDGYTCYPD AEVTTTDEPPKPQCIEEMCWCSSGWEYRNNECVRQEEETRTADYDRDLSARPLPECYEDNCICPWGHNYDRSKEICVPRP GYKHETMGPSGVHLSCNVMNRCHPYAQCIYVTSTADYECRCNQGYEGDGMECIKTEVSCLEVDICDPNASCQQEESLAKC VCNPGFEGDGTMCSPIDECSSSSYCLENERCLYNSASSRYECTCNPGYSMVDSRCVVSDCSTNPSQCHVNAQCTSIGEGG YRCVCAEGYNGDGIRQCVEDHIGCNVLNNCGRNAVCGYNQTSANFVCVCQQGYYGDGFTCLPQSSCRHDPAICSPDATCV AAGENQYACVCNEGFIGDGTNCKSRPKHEANFLLVNQGMATLRIPFAPTYEDPGSPIYIAYMQMAIAIDIDCMNGKAYSS DISGNRIIELTYNGSMAETFLPKVSNPEGLAIDWVSRNIFWTGKTTVEVANLETKKRKVLVSDGLVNPRGIAVHPYRGKI FWSDWNRASPKLEWANEDGTDRAIFLQGDYVKLPNSLSIDWAMDELCWADAGTFTISCMEIDSRKINVVANQLTYPFGLA ISQQHYYWTDWKTHKIEVAMKSTGDRKQAISVPPGGSGKLYGIVVVPESCPRVTNACQFEGGRCSKNQLCLPNGQNGRSC VCADDADGPCTDNL >XP_039259166.1 nidogen-like [Styela clava] MKTVAVLLAVFAVGQSAVFNDFYPFDRENDHRVPKGDNTSSPQFELDLPIIFYDSVYNGIKVNADGFVTLGVVEHEIEEH LLEPVLVPFGFNLNNTDASEIYYQEHKDEATLSRATNDIQKAFVETAEAFVAKSAFIVTWVRLESPEHPGLTFTFQCVVV SNHLSSFAIFLYADDELAAGQSEEIRNQLIAKAGFSDKGGDQLESMTATELLEGGNAWSTGEWIFQIGGVLLSLEEEEEI PSHHLKAEPIHHRRESGFEVPEVNFNEDYGSDQQDCDSLECDPEFSTCTAFADGYCCQCSEGSFGNGYACIREDDDVRYN GQVDGYSIVMSDPWSNETAKGVDMHSYVVTKDGRAFSVMNGEISAKLYRALQPMAIFGTTLGWLFAQAEAPAINGFQYSG GKIVSETYIRYTTGQYEFRIRQEYDQVINDPEGGEGKVLNGRMTFSGRLPPVEEGENINVDDYTQIYKRTGADSIRSRDT RRYIVGDTEHIFTVDQSIRFEGCEASFEEVPADLAVDVSEVFLKFFPDENNLRFAVNSRIRPAEEVGVRPVEPSIIPDTP VPDTPVPDTPEPTPSETPVEKPEEPEIPEVVVTPATQTVCERQLQQVQQFQRENPGIVDEIFFPTCTDVGTFAPRQCLTY NSICWCVDEDTGEEIHGTRTEPLVGYQLDCSDVRAPPPAQTPCQEDRSNAETDRIVAGSEANSIFMPRCMESGAYEPVQQ LPDGSFMCVDFDGEEISRSTEMPNCLTPCQLAAYVAESSNIFLETNEFVVRCKADGDYNPEQCVETYCYCVDENGLEITN SRVETTFGEDVDLDCGKFNSKPVTSTVTTPTTTTGPIVGQEVRRLLFAQTMGINVIDLPVTRENSVSRRLFARSDQITIA LGYDCSSKKYYWTDVSKRRIYSSVLDGDGSRAQFLGDRLRSPEGISVDFLSGNVYWTDSEYDRIEVASADGSNRMTVVSG DIVNPRGIAVDPIRGRMYWTDWNRKAPKVWVANMDGSDRRVLLSEGLGLPNDITIDFYRQRVCFVDAGTFKVECMSLNGE GRETIYQMKQVPRPHPFGLAVDGDVLYYSSWGGSKVVHAVNWRTGDSIAIAGPRGAHGQMYGVEIAHSQCPRGYNYCSSN NGGCSHLCLPTPTGRECVCPPGAQDCQ >NP_001256467.1 NIDogen (basement membrane protein) [Caenorhabditis elegans] MKHKKMLILLFLYLLIETTTANPAFYPYGQPAGDNRLDYSMEQSAIALKIPLTYMEQSVDELFLSHNGIVGLGKPTPEKI GGLMTISTPAIAVFYVPVTSGVIDYRVSSDDQGLLTKLTQDVKQVFADAVEFHGLQAVIITWTQIENAEKDGPASFQLAI VSDGISTYAIFRYESLPWSSSMGYYAQAGFVRSIGKIQTNVNSGGPDVKELVNLSNNQFGNFFIFRVSGSAIEDPKDEGA DDYDYNNYDQEYEGEHPADCPKDKFVDNCPAECRTVRDERGCERCICAERPHAPRAPQEPRPELENTVEDDEDDEQVDGT RYEEPARQAQEQHHQQHHQPDQPQQQPQRSQEGSLPKMSCSQRDDKSCHANSVCQDFEGGFCCNCDTGFYGNGKECLPKG EPQRISGSFEGVINRIPIDKTELHTFATSTDGNVHTAVSKIPSDLGHPLRFLYSIGGVMGWLFADVQSPNVYNGFQLTGG LFNRTVALHIEQNYYVTIKQEFSGRNIHDYFKSHLFVSGTLPDIAPGSEVIFPDYEEEYVRERRGYLTSKAAFDVIVRDG GNVQTYRMSVDQQITFEECPNKEFDRDHSMKLHVKRINVVYNDDEGVVRYGAKNFATRSVGPAVSAPSGGHFDRRQHGQS NMASERPIEIPSQSESISTDSVCAPGRHQCTLPNMKCRVVDPSYRCECEPGYQAAHDASSHIGWICQDLDECQRGDHNCD QHAKCTNRPGSFSCQCLQGYQGDGRSCIREHQASHHEHNQQTPQEMAGVGATTEGFCTAHNQCHQWGECVFTSEHPTGRC KCRGWYVGDGVNHCGPPEENMPKHNANIPQRGGQACGSYVCDVNAECMPEPSGGSECVCKAGFSGNGVTCESLLDDRHAH SSHNRHEQQQQTGSLGKVCRSHDECSEHGSCAYHHSLGYYQCACTEPYVGNGVECTLPGSSASAESSTRSDKLLVARGMA IFERSTNPDEYGKQLIVIPHHIPVGIDFDCKEEKIVWSDMSGHSIRTSSLNGTEHKSYFNKELSSPEGIAVDWSSRNVYY ADSMNDEIGVASLNGKFKKSLVTEGLVNPRSVVLDLYGRHLYYSDWHRENPYIGRVDMDGKNNRVFLNEDVHLPNGLTIL PNRRELCWVDAGNHRLSCIQYNGAGRRTVFSSLQYPFGLTHDEEQKFYWTDWKDNRIHSVGVYGEGYRSFQISLGGSGKV FGILAVPKSCVGPSTPCSEDNGGCQHLCLPGQNGAVCECPDNVKVKGC >NP_610575.1 Nidogen/entactin, isoform A [Drosophila melanogaster] MPTFGSKLLACLLLSSVILVSGQFEHYLDSLRASELYEFEDGSLGSIHLLPKGDSETIVLQLEQPIHFYGEQYEQLYINT NGILTFNSEFPEYLNQPFPLEYASIAAFYSNVDTSFSDEGTSISLFESKEQSILDRASSLVRYAFSSQSEFEARQVIVAT WRNVGYFDSKTDRLNTFQVALIANEQSTFVQFIYPDGGLNWLQGETAGLGLPDIRAQAGFVAEDGRFYTLNGSGSENARF LSESTNLGVPGVWLFEVAPIENEQNVRSPDNAESLTESPALALSCQAHAHQCHEKAECHDKAEGYCCVCGSGFYGNGKSC LANDQPIRVTGTLTGELNKQPVSEEAKLQSYVVTSEGRTYTTINPLTPELGAQLRLVLPLLTTVPWLFAKSVGGVANGYQ LTGGVYTHVSRLQFDSGENLHVNQTFEGLNYWDQLSVKIEIYGEVPAVAADAVLILPDYVEEYTFERPGELKSVQVLNIN ITEEQRVLGLQVEQRILYRSCLRDDEADPSATKVLQKISKVALDYVERDQALRIGAMSKVGVTPESNACNDGTADCVENS VCVPYEDTYRCDCYHGFAAQLDERGVEVCLDIDECATGSHVCDENAVCDNTEGGFNCYCTEGFEGNGYRCLSNSTADNIE YPPAVEGQAEPTSEPSPNPSPYPDQGQDQEREREDDQYPQPNPYPYPEEQIPQHPDECYRCSKDADCYQGRCTCHEGFDG DGYTCTNICGHGEVWENGRCEPLLLERHDVDPLCDALGECRCPYGYELSEDSQRCTYVQEFDGERNADLIPCDVDENCHI NATCNWYGQELRHICTCQPGFRGDGYNCDPISDDSCAIRPDICDVHADCVYEEHLGKSECQCQAGYTGNGFNCQLAAECQ SAEHCGENAFCDDGVCRCQADFERDVSDRCVPAGRCGSVFCGSNAICKWDSAEGVQYCDCLDGYQGDALTGCTSKPLSCH VLNNCGIHATCEPTEDPANYECQCIAGFKGDGYVCIEEQNCLNNPTLCDMNAQCRSTNSGLVCVCNQGFFGNGSLCQERQ HQDSDFLIVSQGVMIARVPLNGRNVRPISVAQMAIGLDKDCVEGRVYWGDISTKKIVSTKYDGTDLRPFITTDIESPEGI AIDVISRRLYWADSAKDTIEVASLDDPSLRAVIINKQLVNPRGIAVDPYREKLFWSDWDRESPKIEMSNLDGTGRELLLG KDDVTLPNSLVVLENSGEVCYADAGTKKVECIEPQNRQIRTISNELSYPFGITFTHDQFYWTDWTTKKVEIVDSLGARQT PIQPPFFGSHKMYGMTVVEQHCPQYQSPCQISNGGCTDSRLCLVNRQAPSGKSCKCTSASTGCTVLAPGY >XP_031557799.1 nidogen-like [Actinia tenebrosa] MASRNLVFLLVLLVIQSSCLVLGARIQEFYPDGIDGPRGSSELLARRISPPVTLGTTYNLYGKPYTSLRVYKNGLITLGE EPISFSPQKHRKFLFPPEAKVIAPFYGQGDFTNTSRISYGETRDSDILTRASKDVKQSFSGEDEFNASAVFIVTWCQVKH AQHSQHKKNNTFQAVLVTNGDQTFVIFNYLTRGLQWAKGYHSQWKGAKYAYAQVGFSAGDFVRYSTLPGSGTNQVHWLAS KSNMNTPGRWIYKVGWPGMHGNEVQSADSFEIDDSTNTDFFAAQFYDGCFVVHGYLTANRSQIWKDVSIRSCIALCFERR QKYAALHNGSQCACLNDIRHLIKTNTDQDCDMACSVNDDEVCGGQMTASVYQSVGLAAVQSDQSGGQRKRKDVDECAVGV VSCHANATCINKSPGYCCQCNEGFYGNGITCIEIGAVQRMVGFLSGTVNGEEFISLNMDTIAFSDDGRAYVSVRAFPPYL AHSARVLTPLTDVVGWMYAKPKPSGFYNGYNVVGARFVRRASLRFDSGEELAILQKYQGRDVLSHYMKVETTMNGAIPRI HPKAEVRMRKFRQEFQRTAAGRVQSRGTVKYQVDGREHYFTVDQFIDYDEQKRCGQHVVRGVLEADVLTSNYDPAQAFLG IAVKGTFINTTLDSIDVQSQEADKMCGSKKVTCHTRGVCIQYRGDKECRCNHGYLGDGVTYCDDADECKLGRYRCAPDAD CVNTVGSYRCVCKKGYVGDGKTCQKDSVIQCPRPCGANAKCVKIALGLLCNCNPDYQGDGFDCKPDGTCAGIKCDPNAKC ATSSDKSRKCVCNDGYQGDGQTCTALEGRCGGVVCSTNAQCVQSKCVCNPGFQGNGKNCSDENECELKTHRCDTNADCIN TVGSYSCRCRLGYQGDGLSCQKASASCGGEKCHRFAYCDVDPQTKKQQCKCRRGFRGNGAECLDFNECIPILKTCDVNAL CRNTLGSYECICKRGFIQGSDDDKTCIVDDRCNGIKCDVNARCDRVQGCTCKTGFVGDGKTCNDIDECKSEMTRCDPNAD CRNTAGSFTCSCRSGFEGDGVRCRVDNSCDGVVCNVNARCEVQPDGRTRRCVCSNGWQGNGTLCTDVDECQSSRFSCPPN TDCINSNGSYECRCKRGFEKKGSSCVEDDSCGGVTCDAKARCVQTPQGTRQCVCNTGWQKNGNRCIDKDECQTNPCHPNA DCINSIGSFSCRCKPGYNGNGQACNDVDECQSGQSRCPANTDCINREGSYECRCTTGFVSNGSSCIVDESCGGVKCDPNA KCIQIAQGVRQCVCNAGWEKNGNTCIDVDECRASISPCHSNANCINSIGSFSCRCRPGFKGDGQFCEDDGTCGGVQCHPD ASCHKNTAEGTRCVCKPGYLGDGRKCADIDECIQGKDECHEHATCTNSAGSYKCSCNLGYVGDGFNCTDDGSCQGIDCDP NAKCVASSPTDGNRTCVCNDGFSGNGELCRDVDECDLGHAKCHRKAECVNQVGSYRCRCIRGYVGDGKQCESDGTCEGKV CDFNADCVTTNTTRGIDKTCKCKDGFSGDGVICTDVDECIKDPCPPMSQCVNAFGTYVCQCKPGYKKSNGLCEKICTRCR NGGSCIGENECKCPKGYSGNVCQWYGEASLIYTKGNSVQRMSLPPRSNAIGLVYNHEGMVNVGLDYDCVEEYIYWTEVME GCIMRAKYDGTNRELVFQRSEVRSPEGLSVDWIGRNLYWTDSGLDVIEVSRLNGSNRKVLISNGLYDPRAILVDPPSGKM YWSDWTRRRPRIETADMDGTNRRVLVYDDLGLPNGLTLVQTTNELCYTDAGSWSIRCVDLAGLNVRKVLTRVTYPFGIAY FNRTLYWTDWNQNLIHRIGVESSTPDSSLATFVGKTGKIFDVKAVQPCPAKVPRNPCSDKNGGCLGLCLLKPHGGYTCSC PKGQFPVKDGNQTTCRGKCDDPLGMEKGLISDAQLTASSAWSNNPKRHGAHRARLNLDTWPAGWSTKKFDPKPWVQIDLG THTMVTGVATQGLGKSIGEWVKTYRVAYSDDGVTWYVLRNGGRKKIFVANSDSTTVKRNKFPAALKTRWLRILPRTWHNH VSMRLELYGC
Mafft alignment of selected proteins >sp|Q14112|NID2_HUMAN Nidogen-2 OS=Homo sapiens OX=9606 GN=NID2 PE=1 SV=3 ME--------------------------------GDRVAGRPV----------------- ------LS---------------------------------------------------- -----SLPVLLLLPLLMLRAAALHP----DELFPH---GESWGDQLLQEGDDE--SSAVV KLANPLHFYEARFSNLYVGTNGIISTQDFPRE---TQYVDYDFPTDFPAIAPFLADIDTS HG--RGRVLYR-EDTSPAVLGLAARYVRAGFPRS-----ARFTPTHAFLATWEQVGAYEE VKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQ----LPAR VGFCRGEADDL---KSEGPYFSLT-STEQSVKNLYQLSNLGIPGVWAFHIGST----SPL DNVRPAAV-GD-LSAAHSSVP---LGRSFSHATALESDYNEDNL-D----YYDVNEEE-- -------AEYLPGEPEE-ALNGHSSIDVSFQSKVDTKPLE-------------------- ------------ESSTLDPHTKEGTSLGEVGGPDLKGQVEPWDERETRSPAPPEVDRDSL APSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEI-VLRSYP-ASGHTTPLSRG- TYEVGL-EDNIGSNTEVFTYNAANKETCE--HNHRQCSRH-AFCTDYATGFCCHCQSKFY GNGKHCLPEGAPHRVNGKVSGHLHVGHTPVH---FTDVDLHAYIVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGS-ENGFSLAGAAFTHDMEVTFYPGEETVRITQT AEGLDPE------NYLSIKTNIQGQVPYVSANFTAHISPYKELYHYS-DSTVTSTSSRDY SLTF-GAINQTWSYRIHQNITYQV---CRHAPRHPS-FPTTQQL--NVDRVFALYNDEER VLRFAVTN----QIGPVKEDS----------------------------DPTPGNPCYDG SHMCD-TTARCHPGTGVDYTCECASGYQG----DGRN---CVDENECATGFHRCGPNSVC INLPGSYRCECRSGYEFADDRHTCILI--------------------------------- ----------------------------------------------------------TP PANPCEDGSHTCAPAGQARCVHHGGS-TFSCACLPGYAGDGHQCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPAATC--YNTPGSFSCRCQPGYYGDGFQ- CI---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PDST-SSLTPCEQQQR ----HAQAQYAYP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARF----- ---HIPQCD-EQGNFLPLQCHGSTG----------FCWCVDP-DGH-------------- ----EVPGTQTPPGSTPPHCGPS------------------------------------- ------------------------------------------P-------EPTQRP-PTI CERWRENLLEHYGGT-------PRDDQYVPQCDDLGHFIPLQ------------------ -----------------C------HGKSDFCWCVDK-DGREVQGTRSQPGTTPA------ ---CIPTV-APPMVRPTPR-------PDVTP-------PSVG-T---------------- ---FLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHG-SIIVGIDYDCRERMVYWTDVAGR TISRAGLELGAEPETIVN-SGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDG-SERKV LFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILIN-TDIGLPNGLTF DPFSKLLCWADAGTKKLECTLPDG--TGRRVIQN----NLKYPFSIVS-YADHFYHTDWR RDGV-VSVNKHSG-QFTDE--YLPE-QRSHLYGITAVYPYCPTG--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >tr|X1WE42|X1WE42_DANRE Nidogen 2a (osteonidogen) OS=Danio rerio OX=7955 GN=nid2a PE=1 SV=1 ML---------------------------TSCMCTS------------------------ ----CSPK--------------------------------MTRDK--------------- -----IALLFLQLSWAFHHVAGIDR----HDIYPY---GMFYGDVTLQEGDDE--TSKVI TLSKPMHFYEAPFTNLYVTTNGIISTQDLPME---KQYVDDGFPTDFPVIAPFLADIDTS KG--KGSIYYR-QTESPTVLKRAEADVKRGFPD------ATFSPTHAFIATWENVSAYEE VARSSSPSHRVNTFQVVLAYNEKDTYALFLYPEDGLQFFGTRPKESYNVEIE----LPAR VGFSRGEISYLIFSRTEGPYYSLT-SNEQSVKNLYQKGNIGEPGVWLFHVGNL----YSF QNVVPAQQEAV-SSKSPTVQDTVFTDE----------DYTDE------------------ -------EEYDPIDPDF-------------------------QDPTTTEFLEPE---PDS SLLERLNQE-----TPLGQSP----------------------------------LQPSV SGPEDLPQPDPHHVQP-------EDNTQPQWPLPKHA----ILQVYP-NRVKDVPTHPSD GQVFSV-EEKVDFDSGVIHYSTDNKETCE--RFQQQCSLN-AHCTDHSTGFCCHCNSGFY GNGRHCLPNGAPQRVNGKVRGTVLVGGTAVD---LGNIDLHAYIVVGDGRAYTAIS-EVP EPAGWALMPVAPIGGLFGWLFALELPNS-LNGFSITGAEFTRRADVTFSPGNQRLSIVQT ATGLDNQ------NYLNVDTHLQGSVPFIPPGATVQMEPFKDTYQYY-PSLITSTSVREF KVVSAENGAETFTFQVKQNITYRD---CSHRPRS---RLETLEL--KMERVFVMYVREER ILRYAITN----KIGPLGAVD---------------------------PEPENVNPCYSG NHDCD-TTARCVPGEGQLFSCQCATGYRG----DGRN---CYDVDECAEGLSSCGAHSHC VNLPGSHRCQCESGFQFGFDGRTCQ----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------DVD-------ECG---------------- --------------------------EQPCHAQALC--SNSPGSFRCQCQPGYHGDGFQ- CHPQNGH---------------PKTRCEQHRDSLQSGDGGVPAVG-----AFIPQCDEEG QYRPLQCHGS---TGHCWCVDNRGQERAGTRTPPGSPPRNC-----DEPVRPKTHCEQHR DSLQSE--------------------------------------NG-------------- -----------------------------GVPVVGAFIPQCDEEGQYRPQQCHGSTGHCW CVDNRGQERAGTRTPPGSPRVNC------------------------------------- -DQPVHL-----------------------------------------------RTRCE- QHRDSLQ-SGDGGV------------PAVGAFIPQCDEEGQYRPQQCHGS---TGHCWCV D-NRGQERAGT--------------------RTPPGSPRVNCDQPV---RPKTHCEQHRD S---LQSGDGGIPVVGAFI----------------------------------------- ---------------------------------------PQCDEEGQYRPQQCHGSTGHC ----WCVDSRGQERAGTRTPPGSPRVNCD------------------------------- ----------------------------------------------------QPVRSKTH CEQHRDSLQS-------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------GDGGVPVVGA----- ---FIPQCD-EEGQYRPQQCHGSTG----------HCWCVDN-RGQ-------------- ----ERAGTRTPPGSPRVNCDQ-------------------------------------- ------------------------------------------PVI----VPPTQRP-ESV CERWRASLLQQYGGQ-------PDSQHYLPQCDSAGEFNPVQ------------------ -----------------C------YGGSSYCWCVDA-NGREVPGTRSHDAVKPA------ ---CIPTV-ASPTVHPLPR-------PDVTP-------PPTG-T---------------- ---SLLYAQGQQIGVLPLNGTQMDKERSSVLLALHG-SIVVGIDYDCRERKVYWTDLAGR TINRASLDPGSEPEIIIN-TALTSPEGLAVDVARRRLFWVDSTLDKIETANLDG-SDRHV LFATDLVNPRAMIVDSSTGTLYWTDWNREAPKIESSSVDGQNRRVLVQ-EGIGLPNALTY DSTMRQVCWADAGTKRLECISPNG--TGRRVIQS----NLNYPFSMVY-FANHYYYTDWR RDGV-ISLGRDN--QLTDE--YLPD-QRSHLYGITVAPPQCL------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >NP_032721.2 nidogen-2 precursor [Mus musculus] MF--------------------------------RDPTAGWLT----------------- ------PP---------------------------------------------------- -----SPLSLLVMLLLLSRVGALRP----DELFPY---GESWGDQLLPEGDDE--SSAAV KLAIPLRFYDAQFSSLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS HS--RGRILYR-EDTSGAVLSLAARYVRTGFPLS----GSSFTPTHAFLATWEHVGAYEE VSRGAAPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQ----LPAR VGFCRGEADDL---KREALYFSLT-NTEQSVKNLYQLSNLGIPGVWAFHIGSR----FAL DNVRPATVGGD-PSTARSSA----LEHPFSHAAALES-YTEDSF-H----YYDENEED-- -------VEYPPVEPGE-APEGHSRIDVSFNSKADPGLVDVGTSSPGSDRASPW----PY PAPGNWPSYRETESASLDPQTKQGRPVGEGEVLDFRDPAELLDQMGTRAPAPPEADAALL TPVNEDL----GGRNTQSYPEAGPVPSEPDV-PVPPLEGE-VLPHYP-ESGHVPPLRGG- KYVIGL-EDHVGSNDQVFTYNGANLETCE--HSHGRCSQH-AFCTDYTTGFCCHCQSRFY GNGKHCLPEGAPHRVNGKVSGRLRVGHIPVH---FTDVDLHAYIVGNDGRAYTAIS-HVP QPAAQALLPVLPIGGLFGWLFALEKPGS-ENGFSLTGATFVHDVEVTFHPGEERVRITQT AEGLDPE------NYLSIKTNIEGQVPFIPANFTAHITPYKEFYHYR-DSVVTSSSSRSF SLTS-GSINQTWSYHIDQNITYQA---CRHAPRHLA-IPATQQL--TVDRAFALYSEDEG VLRFAVTN----QIGPVEVDS----------------------------APVGVNPCYDG SHTCD-TTARCHPGTGVDYTCECTPGFQG----DGRS---CVDVNECATGFHRCGPNSVC VNLVGSYRCECRSGYEFADDQHTCILI--------------------------------- ----------------------------------------------------------AP PPNPCLDGSHTCAPEGQARCIHHGGS-SFSCACLPGFIGTGHQCS--------------- -------------------------------DVD-------ECA---------------- --------------------------ENRCHEAAIC--YNTPGSFSCRCQPGYRGDGFH- CTSDTVP----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------EDSI-SGLKPCEYQQR ----YAQTQHAYP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GSRI----- ---HIPQCD-DQGNFVPLQCHGSTG----------FCWCVDR-NGH-------------- ----EVPGTQTPPGSTPPHCGPP------------------------------------- ------------------------------------------P-------EPTQRP-RTV CERWRESLLEHYGGT-------PRDDQYVPQCDDLGHFIPLQ------------------ -----------------C------HGKSDFCWCVDK-DGRELQGTRSQPGTRPA------ ---CIPTV-APPVVRPTPR-------PDVTP-------PSVG-T---------------- ---FLLYAQGQQIGHLPLNGSRLQKDAARTLLSLHG-SIVVGIDYDCRERMVYWTDVAGR TISRASLEAGAEPETIIT-SGLISPEGLAIDHFRRTMYWTDSGLDKIERAELDG-SERKV LFHTDLVNPRAITVDPIRGNLYWTDWNREAPKIETSSLDGENRRILIN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECTLPDG--TGRRVIQN----HLNYPFSIVS-YADHFYHTDWR RDGV-ISVNKDSG-QFTDE--FLPE-QRSHLYGITAVYPYCPTG--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >NP_001012005.2 nidogen-2 precursor [Rattus norvegicus] MS--------------------------------WDPTAGRLA----------------- ------PP---------------------------------------------------- -----SPLSLLLVLVLLSRVGALRP----EELFPY---GESWGDRLLPEGDDE--SSAAV KLAVPLRFYDAQFSNLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS HS--RGRILYR-EDTSQAVLSLAARYVRTGFPLT----GSSFTPTHAFLATWEHVGAYEE VRRGAAPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQ----LPAR VGFCRGEADDL---KREALYFSLT-NTEQSVKNLYQLSNLGIPGAWAFHIGSR----LAL DNVRPATVGGD-HSTARSSA----LEHSFNHAAALES-YTEDSF-D----YYNENEED-- -------VEYPPIEPGE-ALEGHSRIDVSFNSEVNP-------TSPDSDHASPL----PH PAPGNWPSYRETESASLDPQTKQGPPVGEVEVLDFKDPAELLDQTGTRTPAPPGADAAFL TPGREDL----GNRDTQSYPEARPVPSEPDV-PVAPLERE-ILPNYP-ESGHVPPLSGG- RYVVGL-EDHVSSKDQVFTYNGANRETCE--HSHGQCSRH-AFCTDYTTGFCCHCQSRFY GNGRHCVPEGAPHRVNGKVSGHLQVGHMPVH---FTDVDLHAYIVSNDGRAYTAIS-QIP QPAAQALLPVLPIGGLFGWLFALEKPGS-ENGFSLTGATFVHDVEVTFHPGEERVRITQT AEGLDPE------NYLSLNTNIEGQVPFIPANFTAHIAPYQEFYHHR-DSVVTSSSSRSF SLIS-GSINQTRSYRIDQNITYKA---CSHAPRHLA-VPATQQL--TVDRAFALYSEEEG VLRFAVTN----QIGPVEVDS----------------------------APTAVNPCYDG SHTCD-TTARCHPGTGVDYTCECTPGFQG----DGRS---CVDVNECATGFHRCGPNSVC VNLVGSYRCECRSGYEFADDRHTCVLI--------------------------------- ----------------------------------------------------------AP PPNPCLDGSHTCAPEGQARCIHHGGS-SFSCACLPGFVGTGHQCS--------------- -------------------------------DVD-------ECA---------------- --------------------------ENRCHGAAIC--YNTPGSFSCRCQPGYHGDGFH- CASDTVP----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------EDSI-SGLKPCEYQQR ----YAQAQHAHA----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GSRI----- ---HIPQCD-DQGNFVPLQCHGSTG----------FCWCVDQ-NGH-------------- ----EVPGTQTPPGSTPPHCGPP------------------------------------- ------------------------------------------P-------EPTQRP-RTV CERWRESLLEHYGGT-------PRDDQYVPQCDDLGHFIPLQ------------------ -----------------C------HGKSDFCWCVDK-DGRELPGTRSQPGTMPA------ ---CIPTV-APPVVRPTPR-------PDVTP-------PAVG-T---------------- ---FLLYAQGQQIGHLPLNGSRLQKDAARTLLSLHG-SIVVGIDYDCRERMVYWTDVAGR TISRASLEAGAEPETIIT-SGLISPEGLAIDHFRRTMYWTDSGLDKIERAGLDG-SERKV LFHTDLVNPRAITVDPIRGNLYWTDWNREAPKIETSSLDGENRRILIN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECTLPDG--TGRRVIQN----HLNYPFSVVS-YADHFYHTDWR RDGV-ISVSKDSG-QLTDE--YLPE-QRSHLYGITAVYPYCPTG--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >CAE1293091.1 LRP5_6 [Sepia pharaonis] ML---------------------------------------------------------- ------------------------------------------------------------ ---------------------------------PP------------------------- ------------------------------------------------------------ -----GYIKYH-SQHS------CVGSIERGF--------LCFGSPLLLFANRKDVRLVDA -------ANSRNS-SVIISGLEDAAAVDFYYAENSVFWT--------DVSLE----MIKR TYV----------------------NGSQTSTNVITFGLLSPDGLALDWLGEKLYWTDSE TNRIEV------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------SNLNGSCRKILFWEHLDQPRAIALDPLNGYMYWTDWG-- --------------------------ERP-K---IERAGM-------DGSKQNRSV---- -----------IISERIHW----------PNGLTLD----YEDSKIYWADAKLNFIHSCN FDGSDRQ------------PVVQGSLPH---PFALTLFEERLFWTDWHTRAIHSCHKRT- -----GGN---------REVVHSD-------------IYSPMDI---------------- ------------HVYTAKRQP------------------------------ASNNPCGNN NGGCS------------------------------------------------------- ---------------------HLCLMS--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------P----------------- ------------------------------------------------------------ ------------------------QPPFFSCACPTG------------------------ -----------------VRLHENGHTCASSPK-----------E---------------- ---ILLLARRSDLRRISLDTPD----YTDVILQLSDIRHTIAIDYDTVEDYVYWTDDEVH LIRRAHMD-GSGQEVIVS-TEVEHPDGVAVDWIGRNLYWTDTGTDRIEVCRLNG-TSRKV LISEGLVEPRAICLDPMRGHMYWTDWGAN-PKIERANMDGTERIALIN-SSLGWPNGVAI DYQEKKLYWGDAKTDMIEVANLDG--TDRKVLVSN---NLPHIFGFSL-LGDYVYWTDWQ RRSI-ERVHKVTGGERQVIIDQLPD-----LMGLKAVNMNHVEG--SNGCAENNGGCSH- -LCLNTHP--KGPVCACPTGIFFELLDDQKTCVVPDGFLLFSRKEDIRRMSLETNHNDVL IPIQGVKDAHALDFDNSDNRIYWTDASLKQISRAFMNGSSLEHIIEFGIEFPEGMAVDWV AKNLYWTDIGTKRIEVARLDGKSRRVLIWKDLSDPRSIVLDPPNGYMYWTDWGENPKLER ATLDGKNRKTSDMLGQDRRVMVDTHLLSPRGITQYK-DFIYWTDLEKKSIERAHKL-TGH NRTTIHQGHGDYVMDILVFQESRQPGWNPCGVDNGNCSHLCLAHPSPPDQTGTANMTFSC ACPT------------HYTLDADNKTCLRK >XP_015132255.2 nidogen-2 isoform X1 [Gallus gallus] MR---------------------------------------------------------- ------------------------------------------------------------ ------AAVAALAAAAVAVAAALPR----TELLPY---GAAHGDGRLRHGDDE--SSPGV VLRPPMRLYGRAARRLFVGTNGVISTQDFPGE---TQYVDDDFPTDFPVIAPFLADLDTS GG--RGDIYYR-QDRAPTVLEWAAGYVHAGFPDT----AGTFVPSSAFIATWEDVGAHGE ------PPGKLNTFQAILAYNEEETYAIFLYPEGGLQFLGTRPKESYNVQLE----LPAR VGFSRGDGDDG---KREGHSYSVA-SSQQELQRLERESNVGVPGVWVFRVGT-------L ENVEPGDV----PGAALSPAPHGTDDTS-----------VPTEL---------------- ------------------------------------------LAQPGSRTTSPH----PH --------------------------------------------------------PALL SIVPSGLPASPLG--------------QEWSPRLHSIGD-----APQ---GHPVSYSSG- QHGVGV-EEDVHFNTNVFTYSAGSRETCA--QHHGRCSPH-AFCTDYATGLCCHCRAAYY GNGRQCLPEGAVHRLNGKVSGSLVVGRTPVR---FQDVDLHAYIVGSDGRAYTAIS-GVP APAARALLPLLPLGGLFGWLFALEEPGS-ENGFSITGAEFTQYLEVTFYPGEEQVRITQM AEGLGAD------NYLSLRTHIEGQVPFVPENTSVHIAPYKELYHYS-SSAVTSSAHRDY VLTS-GSTNQTLSYRLRQNITVVG---CPHARGR---LPTVQQL--SVARAFALYDGHEQ VLRYALTS----RISSSRGDA----------------------------EVPPVNPCHDG THACE-ETARCQPGTGLGYTCECAAGYRG----DGRG---CQDVDECEEGLGQCGPFSVC LNVLGSYRCECHSGYRPAEDGHGCVLP--------------------------------- ----------------------------------------------------------TP AADPCEVGRHPCAPRDRARCLPRAGG-QPACECLPGYAGDGRVCS--------------- -------------------------------DVN-------ECT---------------- --------------------------LNLCHPAAIC--YNTPGSFSCQCQPGYEGDGFQ- CTHAQSS----------------------------------------------------- -------------------------------------------------TQRLTPCEHE- ------------------------------------------------------------ ---------------------------------------------QLYPRT--------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------PGHVPQCDEQGGYQPLQCHSG---SGHCWCV D-SSGQEIAGT--------------------RTAAGSTPPRCGNPGSS-QQLTPCEHERL ----YPRAVPPGP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------SPVGNG----- ---HVPQCD-EQGNYRPLQCHGSTG----------YCWCVDG-AGQ-------------- ----EIAGTRTAPGSTPPRCGS-------------------------------------- ------------------------------------------P-------EPSERP-PTM CERWRQSLLEHYGGS-------PRGDQYVPQCDAHGHFTPLQ------------------ -----------------C------HGDSGYCWCVDE-SGREIQGTRSEPGSPPP------ ---CLPSV-APPTVRPSPR-------PDVSP-------PAAG-T---------------- ---FLLYAQGQQIGYLPLNGTRLQKEAAKTLLSLHG-SIVVGIDYDCREKTIYWTDVAGR TISRASLEPGAEPETIIN-SGLISPEGLAVDHLRRAMFWTDSGLDKIERAQLDG-SERRV LFDTDLVNPRAITVDPVRGNLYWTDWNREAPKIETSTVSGANRRVLVN-TDIGLPNGLTF DPFSKLLCWADAGTKKLECTFPDG--AGRRIIHN----NLNYPFSIIS-YASHFYHTDWR RDGV-IAVNKETG-SFTDE--YLPE-HRSHLYGITAVYPYCPGA--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_009426087.1 nidogen-2 isoform X1 [Pan troglodytes] ME--------------------------------GDRVAGRPV----------------- ------LS---------------------------------------------------- -----SLPVLLLLPLLMSRAAALHP----DELFPH---GESWGDQLLQEGDDE--SSAVV KLANPLHFYEARFSNLYVGTNGIISTQDFPRE---TQYVDYDFPTDFPAMAPFLADIDTS HG--RGRVLYR-EDTSPAVLGLAARYVRAGFPRS-----ARFTPTHAFLATWEQVGAYEE VKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQ----LPAR VGFCRGEADDL---KSEGPYFSLT-STEQSVKNLYQLSNLGIPGVWAFHIGST----SPL DNVRPAAV-GD-LSAAHSSVP---LGRSFSHATALESDYNEDNL-D----YYDVNEEE-- -------AEYLPGEPEE-ALNGHSSIDVSFQSKVDTKPLEGRISPPDSHLSSPL-----H PTPTYWPFYPETESSTLDPHTKEGTSLGEVEGPDLKGQVEPWDERGTRSPAPPEVDRDSL APSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEI-VLRSYP-ASGHTTPLSRG- TYEVGL-EDNIGSNTEVFTYNAANKETCE--HNHRQCSRH-AFCTDYATGFCCHCQSKFY GNGKHCLPEGAPHRVNGKVSGHLHVGHTPVH---FTDVDLHAYIVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGS-ENGFSLAGAAFTHDMEVTFYPGEETVRITQT AEGLDPE------NYLSIKTNIQGQVPYVPANFTAHISPYKELYHYS-DSAVTSTSSRDY SLTF-GAINQTWSYRIHQNITYQV---CRHAPRRPS-FPTTQQL--NVDRVFALYNDEER VLRFAVTN----QIGPVKEDS----------------------------DPTPVNPCYDG SHMCD-TTARCHPGTGVDYTCECASGYQG----DGRN---CVDENECATGFHRCGPNSVC INLPGSYRCECRSGYEFADDRHTCILI--------------------------------- ----------------------------------------------------------TP PANPCEDGSHTCAAAGQARCVHHGGS-TFSCACLPGYAGDGHQCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPAATC--YNTPGSFSCRCQPGYYGDGFQ- CI---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PDST-SSQTPCEQQQR ----HAQAQYAYP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARF----- ---HIPQCD-EQGNFLPLQCHGSTG----------FCWCVDP-DGH-------------- ----EVPGTQTPPGSTPPHCGPS------------------------------------- ------------------------------------------P-------EPTQRP-PTI CERWRENLLEHYGGT-------PRDDQYVPQCDDLGHFIPLQ------------------ -----------------C------HGKSDFCWCVDK-DGREVQGTRSQPGTTPA------ ---CIPTV-APPMVRPTPR-------PDVTP-------PSVG-T---------------- ---FLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHG-SIIVGIDYDCRERMVYWTDVAGR TISRASLELGAEPETIVN-SGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDG-SERKV LFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILIN-TDIGLPNGLTF DPFSKLLCWADAGTKKLECTLPDG--TGRRVIHN----NLKYPFSIVS-YADHFYHTDWR RDGV-VSVNKHSG-QFTDE--YLPE-QRSHLYGITAVYPYCPTG--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_038443101.1 nidogen-2 isoform X1 [Canis lupus familiaris] MR--------------------------------GDRAARRLALP--------------- -----PLP---------------------------------------------------- -----LPPPPLLLLLLLARAAALHP----GELFPY---GQSRGDQLLQEGDDE--SSAAV KLASPLHFYEAQFSYLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS QG--RGRVLYR-EDTSLAVLGQAARYVRAGFPRT----AARFTPTHAFLATWEQVGAYEE ATSRAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLE----LPAR VGFCRGETDDL---KREGPYFSLT-STEQSVKNLYQQSNLGIPGVWAFHIGST----SPL DNIRPATIGGD-LTKAHPSPP---PEQSFRPEAALESDYTEDNL-D----YYDENEGE-- -------VEYPPSEPEE-AWNGHSSIDVSFQAKAELGPGGGGISPPDSVPASPL---PPH LTASDGQSYPETESATLDPQTKEGRVLEGRDVPDLNGRVESSEQPGTRGPAPSEIESDSL DPTRGTPPPHPGR---------GAPLSEEDVPPAHPGGKE-VLLNYS-VPAH-TPLGQG- RQVLGV-EDVIGSSTEVFTYNAANKETCE--HNHRQCSRH-AFCTDYTTGFCCHCQSRFY GNGKHCLPAGAPHRVNGKVSGHLRVGHLPVH---FSDVDLHAYIVSNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGW-ENGFSFTGATFTHDMEITFYPGEERVQITQT AEGLDPE------NYLSIKTNIQGQVPYIPANFTAHIAPYKEVYHYL-DSAVTSTSSRDY SLIF-GAINQTRSYRIYQNITYQA---CRHAPRHWA-IPTTRQL--NVDRVFALYTEEES LLRFAVTN----QIGPVEENS----------------------------EPTPVNPCYDG SHTCD-ITARCHPGTDVDYTCECASGYQG----DGRS---CVDVNECATGSHHCGPNSMC VNLPGSYRCECRSGYELADDRHTCVLI--------------------------------- ----------------------------------------------------------AP PSNPCEDDSHTCAPAGQARCIYHGGS-TFSCACLPGYTGSGHQCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPSATC--YNTPGSFSCQCHPGYHGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PDPA-SGLKPCEQQQH ----HAHAQQAYP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GSQL----- ---HIPQCD-DQGHFLPLQCHSSTG----------FCWCVDP-DGH-------------- ----EVPGTRTPPGSTPPHCRP-------------------------------------- ------------------------------------------P-------EPTQRP-QTV CERWRENLLEHYGGT-------PRDDQYVPQCDDLGHFIPLQ------------------ -----------------C------HGKSDFCWCVDQ-DGREVQGTRSQPGITPA------ ---CIPTV-APPTVRPVPR-------PDVTP-------PSVG-T---------------- ---FLLYAQGQQIGHLPLNGTKLQKDLAKTLLSLHG-SIVVGIDYDCHERMVYWTDVAGR TISRASLQPGAEPETIIN-SGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDG-SERKA LFHTELVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLEGENRRILVN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECTLPDG--TGRRVIQN----NLNYPFSIVS-YADHFYHTDWR RDGV-ISVNRDSG-QFTDE--YLPE-QRSHLYGITAVYPYCPAG--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >NP_001095535.1 nidogen-2 precursor [Bos taurus] MR--------------------------------GDQAAGWPA----------------- ------PP---------------------------------------------------- -----PPPLLLMLLLLLSRAAALHP----SELFPY---GQSRGDQLLQEGDDE--SSAAV KLTLSLRFYDAQFSDLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS GG--RGRVLYR-QDTSPGVLGLAASYVRTGFPLS----GAHFTPTHAFLATWEQVGAYEE AKRGAPPSGELNTFQAVLASDEFDTYALFLYPANGLQFFGTRPKESYNVQLQ----LPAR VGFCRGEVDDL---NRQGPYFSLT-STEQSVKNLYQHSNLGIPGVWAFHIGST----SPL DNVRPATIGGD-LSKARPSAP---LGQSFSHAVALEDDYTQDTL-D----DYDENEEE-- -------IEYPPSEPAE-ASNGHSSVDVSLGGR---------ISAPDSDLASPE----PR SASQSGP---ETESSPLDPHTKERRLQGETDAPDLKGRVKSSEQPGTRVPAPPETEGDSP APPGEAPPPSPEG---------GAGPADQDALPAHPGGEA-ALPNYP-GPDHGPHLGQR- GQVVGV-EDDISSNTEVFTYNAANKETCE--HNHERCSRH-AFCTDYATGFCCHCQSRFY GNGKQCLPEGAPHRVNGKVSGHLLVGHTPVH---FTDVDLHAYVVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGW-ENGFSLTGATFIHDVEVTFYPGEERVRITQT AEGLDPE------NYLSIKTNIQGQVPYIPANFSAHVAPYKELYHYA-DSAVTCTSTRTY SLMS-GAINQTQTYRIHQNITYQV---CRHAPRHWA-VPVTQQL--NVDRVFALYSDEEK VLRFAVTN----QIGPVEGDS----------------------------EPTPVNPCYDG SHTCA-TTARCHPATGVDYTCECASGYQG----DGRN---CVDVNECATGFHRCGPNSVC VNLLGSYRCECRSGYEFADDRHTCILI--------------------------------- ----------------------------------------------------------TP PPNPCEDGHHNCAPASQARCIHHGDG-SFSCACLPGYAGDGHRCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPSATC--SNTPGSFSCRCQPGYYGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------P-------EPTQRP-RTV CERWRESLLEHYGGT-------PRDDQYVPQCDDLGHFTPLQ------------------ -----------------C------HGKSDFCWCVDQ-DGREVQGTRSQPGITPA------ ---CIPTV-APPTVRPTPR-------PDVTP-------PPVG-T---------------- ---FLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHG-SIVVGIDYDCRERMVYWTDVAGR TISRASLEPGAEPEMVVN-SGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDG-SERRA LFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECILPDG--TGRRVIQN----NLNYPFNIVS-YADHFYHTDWR RDGV-IAVNRDTG-QFTDE--YLPE-QRSHLYGITAVYPYCP-G--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_020957573.1 nidogen-2 isoform X1 [Sus scrofa] MR--------------------------------GYRGARRPA----------------- ------LR---------------------------------------------------- -----AP--PLLLLLLLSRAVALQP----DELFPY---GQSLGDQLLQEGDDE--SSAAV KLALPLRFYDAQFSDLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS HG--RGRVLYR-EDTSPDVLSLAARYVRTGFPRS----AAHFVPTHAFLATWERVGAYEE PKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLE----LPAR VGFSRGEVDDL---KREEQYFSLT-STEQSVKNLYQHSNLGIPGVWAFHIGSA----SPL DNVKPAIAGGD-LSKAHPSVP---LRHSSSHAVAPEGEDTEDNL-D----YYDENEEE-- -------VEYPPGETEE-ESNGHSPDDVSFHSRADLKPSGGGISLPGSDLPSPL----PR PTSRDGL---ETESATLDPQTKEGRPQEEIDAPDLKGRGETSEQPGAQVPAPPKTERDSP DPSWAALPPHPDE---------GALPAERDVPPVPSGGEV-VLPNYPRRPDHAPPLGRG- RQVVGV-EDDIGSNTKVFTYNAANRETCE--HNHERCSRH-AFCTDYATGFCCHCQSRFY GNGKHCLPEGAPHRVNGKVSGHLLVGHTPVH---FTDVDLHAYVVGNDGRAYTAIS-HIP QPAAQALLPLMPIGGLFGWLFALEKPGW-ENGFSLTGATFIHDMEVTFHPGGERVRITQT AEGLDPE------NYLSIKTNIQGQVPYIPANFTVHITPYKELYHYS-GSAVTSTSSRAY SLTY-GAINQTRSYSIHQNITYQT---CRHAPRHWA-IPTTQQL--NVDRVFALYTDEEK VLRFAVTN----QIGPVEGDS----------------------------EPAPVNPCYDG SHTCA-TTAQCHPATGVDYTCECASGYQG----DGRR---CVDVNECATGFHRCGPNSVC VNLPGSYRCQCRSGYEFVDDRHTCVLI--------------------------------- ----------------------------------------------------------AP PPNPCEDGSHNCAPTSQARCIHHGGR-SFSCACLPGYAGDGHQCA--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPSATC--SNTPGSFSCHCQPGYHGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PDPA-LGLKPCEHQQR ----EAQAQRTHP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARL----- ---HIPQCD-EQGHFLPLQCHGSTG----------FCWCVDP-NGQ-------------- ----EVPGTRTPPGSLPPHCGP-------------------------------------- ------------------------------------------P-------EPTQRP-RTV CERWRESLLEHYGGT-------PRDDQYVPQCDDLGHFTPLQ------------------ -----------------C------HGKSDFCWCVDQ-DGREVQGTRSQPGTTPA------ ---CIPTV-APPTMRPTPR-------PDVTP-------PPVG-T---------------- ---FLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHG-SIVVGIDYDCRERMVYWTDVAGR TISRASLEPGAEPETIVN-SGLISPEGLAIDHFRGTMYWTDSGLDKIERARLDG-SERRA LFHTDLVNPRAIAVDPIRGNLYWTDWNREAPKIEMSSLDGENRRILVN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECTLPDG--TGRRVIQN----NLNYPFSIVS-YADHFYHTDWR RDGV-ISVNRDSG-QFTDE--YLPE-QRSHLYGITAVYPYCPTG--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_008267875.2 PREDICTED: LOW QUALITY PROTEIN: nidogen-2 [Oryctolagus cuniculus] MA--------------------------------RTLGRQRPRTPR-------------- ----LPPG---------------------------------------------------- -----AWDWARRGPLLPRRRPWTWT----APGSPD---GRAAG-----AAEDE--GSAQP RPAA-------------------------ASP---SPYVDDDLPXDFPAIAPFLADIDTS GG--RGRVLYR-QDSSPAVLGLAARYVSAGFPRA----AAPFSPTHAFVATWDQVGAYEE VRRGAAPSEELNTFQAVLVSDESDAYALFLYPANGLQFFGTRPKESYNVQLQ----LPAR VGFCRGEADDL---KREGQYLSLT-RTEQSVKNLYQLSNVGIPGLWAFHIGSA----SPL DNVRPAAVGGA-LPAAHSSTP---LKHPFSHAVALKADHPEDSL-D----YYDENEEE-- -------VEYPPAEPEA-A-----TVDIAFHSSTDSGPVAGGLSPPDSDLASPL----PP PASSERPSHLHSESTTGEPPSKQEARLQEVPSPERRPGAQPLGQTGAGSVAVPAVDGDSV APAQEAPTRYPDD------------------------AGD-TLPRYS-VPSLSAPVGGG- RYVAGV-EEDITSNAEVFTYNAAHKETCE--RNHGQCSAH-AFCTDYTTGFCCHCQSSFY GDGKHCLPEGAPHRVNGKVSGHLRVGHTPVH---FTDVDLHAYIVGNDGRAYTAIS-HIP PPAAQALLPLTPLGGLFGWLFALEKPGS-ENGFSLTGATFVQDTEVTFYPGEERLRITQT AEGLDPE------NYLSMKTSIQGQVPYVPANSTAHLAPYKEIYHHS-DSAVTSTSSRDY YLTF-GAVNQTGSYRIHQNITYQG---CRHAPSHRA-IPAAQQL--TVDRVFALYSEEEG VLRFAVAN----QIGPVEGDS----------------------------DPAPVNPCYDG SHTCD-MTARCHPGPGTHYTCECTPGYQG----DGRS---CVDVNECATGFHRCGPNSMC VNLPGSYRCECRSGYTFADDQHTCILM--------------------------------- ----------------------------------------------------------AP PPNPCENGTHTCAPAEQARCIPHGDG-TFSCACLPGYAGDGHQCS--------------- -------------------------------DVD-------ECS---------------- --------------------------ENSCHPAATC--YNTPGSFSCHCQPGYLGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PDSS-SGLKACQQQQL ----YAQAQHARP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTRL----- ---HIPQCD-EQGDFLPLQCHGSTG----------FCWCVNS-DGH-------------- ----EVPGTRTPPGSTPPHCGPP------------------------------------- ------------------------------------------P-------GPTQRP-RTV CERWKESLLEHYGGT-------ARDDQYVPQCDDLGRFVPLQ------------------ -----------------C------HGKSDFCWCVDK-DGREVAGTRTQPGVTPT------ ---CLPEA-VPPLIGAMPR-------PEDS---------LTG-S---------------- ---FLVYAQGQRLGRLPFKRTKLLKDQASTLLSMHG-SIIVGLDYDCHERKVYWTDVAGR VISRIGMQPGAEPEVIIN-SGLLRPEGVAIDFIHRTMYWTDSGLDQIVRTNLDG-SEREI LFYVDLVNPRAITVDPVGGNLYWTDWNRDAPKIERSSLDGTGRRILIG-KDIGLPNGLNF DPVTEMLCWADAGTRKLECTLRDG--TGRRVIQS----NLNYPFSMVS-YIDHFYYTDWR RDAV-ISVNANTG-AVTEE--YLPE-QRSHLYGITAVFPYCPTG--SK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_002824786.2 nidogen-2 isoform X1 [Pongo abelii] ME--------------------------------EDRVAGRPA----------------- ------LS---------------------------------------------------- -----SLPVLLLLPLLMSRSAALHP----DELFPH---GESWGDQLLQEGDDE--SSAVV KLANPLHFYEARFSNLYVGTNGIISTQDFPRE---TQYVDYDFPTDFPAIAPFLADIDTS HG--RGRVLYR-EDTSPAVLGLAARYVRAGFPRS-----ARFTPTHAFLATWKQVGAYEE VKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQ----LPAR VGFCRGEADDL---KSEGPYLSLT-STEQSVKNLYQLSNLGIPGVWAFHIGST----SLL DNVRPAAV-GD-LSAAHSSVP---LGRSFSHATALESDYNEDNL-D----YYDVNEEE-- -------AEYLPGELEE-ALNGHSSIDVSFQSKVDTKPLE-------------------- ------------ESSTLDPHTKEGTSLGEVEGPNLKGQVEPWDERGTRSPAPPEVDRDSL APSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEI-VLRNYP-ASGHTTPLSRG- TYEVGL-EDNIGSNTEVITYNAANKETCE--HNHRQCSWH-AFCTDYATGFCCHCQSKFY GNGKHCLPEGAPHRVNGKVSGHLHVGHTPVH---FTDVDLHAYIVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGS-ENGFSLAGAAFTHDMEVTFYPGEERVRITQT AEGLDPE------NYLSIKTNIQGQVPYFPANFTAHISPYKELYHYS-DSAVTSTSSRDY SLTF-GAINQTWSYRIHQNITYQV---CRHAPRHPS-FPTTQQL--NVDRVFALYNDEER VLRFAVTN----QIGPVKEDS----------------------------DPTPVNPCYDG SHMCD-TTARCHPGTGVDYTCECASGYQG----DGRN---CVDENECATGFHRCGPNSVC INLPGSYRCECRSGYEFADDRHTCILI--------------------------------- ----------------------------------------------------------TR PANPCEDGSHTCAPAGQAQCIHHGGS-MFSCACLPGYAGDGHQCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPAATC--YNTPGSFSCRCQPGYYGDGFQ- CI---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PDST-SSLTPCEQQHR ----HAQAQYAYP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARF----- ---HIPQCD-EQGNFLPLQCHGSTG----------FCWCVDP-DGH-------------- ----EVPGTQTPPGSTPPHCGPP------------------------------------- ------------------------------------------P-------EPTQRP-PTI CERWRENLLEHYGGT-------PRDDQYVPQCDDLGHFIPLQ------------------ -----------------C------HGKSDFCWCVDK-DGREVQGTRSQPGTTPA------ ---CIPTI-APPTARPTPR-------PDVTP-------PSVG-T---------------- ---FLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHG-SIIVGIDYDCRERMVYWTDVAGR TISRASLELGAEPETIVN-SGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDG-SERKV LFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILIN-TDIGLPNGLTF DPFSKLLCWADAGTKKLECTLPDG--TGRHVIQN----NLKYPFSIVS-YADHFYHTDWR RDGV-VSVNKHSG-QFTDE--YLPE-QRSHLYGITAVYPYCPTG--RKM----------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_010710486.1 nidogen-2 [Meleagris gallopavo] MF------------------------LP----GCGERREERSSG---------------- ------------------------------------------------------------ -----PPGPARPQLAAIPAPGAAPR---------Y---PARRGMGMREEEEKG--GREGR T--TPGRILGRAARRLFVGTNGVISSQDFPGE---TQYVDDDFPTDFPVIAPFLADLDTS GG--RGDIYYR-QDHTPSVLEQAAGYVHAGFPYT----TGTFVPSSVFVATWEDVGAHGE ------PPGKLNTFQAILAYNEEDTYAIFLYPEGGLQFLGTRPKESYNVQLE----LPAR VGFSRGDGDDG---KREGHSYNVA-SSQQELQRLERESNVGMPGVWVFHVST-------L ENVEPRNG----PGAALSSAPHGTDDTS-----------VPTEL---------------- ------------------------------------------LAQPGSRTTSPH----PH --------------------------------------------------------PALL SIVPSGLPASPLG--------------QEWSPRLH-FGD-----APQ---GHPVSYSSG- QHGVGV-EEDVHFNTNVFTYSAGSRETCA--QHHGRCSPH-AFCTDYATGLCCHCRAAYY GNGRQCLPEGAVHRLNGKVSGSLVVGRTPVR---FQDVDLHAYIVGSDGRAYTAIS-GVP APAARALLPLLPLGGLFGWLFALEEPGS-ENGFSITGAEFTQYLEVTFYPGEEQVHITQT AEGLGAD------NYLSLKTHIEGQVPFVPESTSVHIAPYEELYRYS-SSAVTSSAHRDY VLTS-GSTNQTLSYRLHQNITVTG---CPHARSH---LPTVQQL--SVARAFALYDGHEQ VLRYALTS----RISSTHDDA----------------------------EVPPVNPCHDG THACE-ETARCQPGTGLGYTCECAAGYRG----DGRG---CKDVDECEEGLSQCGPFSIC LNVPGSYRCECHSGYRPAEDGHGCVLP--------------------------------- ----------------------------------------------------------TP AADPCEVGRHPCAPRDRARCLPRAGG-QPACECLPGYAGDGRVCS--------------- -------------------------------DVD-------ECT---------------- --------------------------LNLCHPAATC--YNTPGSFSCQCQPGYEGDGFQ- CTHAQSS----------------------------------------------------- -------------------------------------------------TQRLTPCEHE- ------------------------------------------------------------ ---------------------------------------------RLYPRT--------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------PGHVPQCDEQGSYRPLQCHSG---SGYCWCV D-ASGQEIAGT--------------------RTAAGSTPPRCGNPGSS-QQLTPCEHERL ----YPRAVPPGP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------SPVGNG----- ---HVPQCD-EQGNYRPLQCHGSTG----------YCWCVDS-AGQ-------------- ----EIAGTRTAPGSTPPRCGN-------------------------------------- ------------------------------------------P-------EPSERP-PTM CERWRQSLLEHYGGS-------PRGDQYVPQCDAQGHFTPLQ------------------ -----------------C------HGDSGYCWCVDE-SGREIQGTRSEPGSPPP------ ---CLPSV-APPSIRPSPR-------PDVSP-------PAAG-T---------------- ---FLLYAQGQQIGYLPLNGTRLQKEAAKTLLSLHG-SIVVGIDYDCREKTIYWTDVAGR TISRASLEPGAEPETIIN-SGLISPEGLAVDHLRRAMFWTDSGLDKIERAQLDG-SERRV LFDTDLVNPRAITVDPVRGNLYWTDWNREAPKIETSTVSGANRRVLVN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECTFPDG--AGRRIIHN----NLNYPFSIIS-YASHFYHTDWR RDGV-IAVNKETG-SFTDE--YLPE-HRSHLYGITAVYPYCPGA--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_008955315.2 nidogen-2 isoform X1 [Pan paniscus] ME--------------------------------GDRVAGRPV----------------- ------LS---------------------------------------------------- -----SLPVLLLLPLLMSRAAALHP----DELFPH---GESWGDQLLQEGDDE--SSAVV KLANPLHFYEARFSNLYVGTNGIISTQDFPRE---TQYVDYDFPTDFPAMAPFLADIDTS HG--RGRVLYR-EDTSPAVLGLAARYVRAGFPRS-----ARFTPTHAFLATWEQVGAYEE VKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQ----LPAR VGFCRGEADDL---KSEGPYFSLT-STEQSVKNLYQLSNLGIPGVWAFHIGST----SPL DNVRPAAV-GD-LSAAHSSVP---LGRSFSHATALESDYNEDNL-D----YYDVNEEE-- -------AEYLPGEPEE-ALNGHSSIDVSFQSKVDTKPLEGRISPPDSHLSSPL-----H PTPTYWPFYPETESSTLDPHTKEGTSLGEVEGPDLKGQVEPWDERGTRSPAPPEVDRDSL APSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEI-VLRSYP-ASGHTTPLSRG- TYEVGL-EDNIGSNTEVFTYNAANKETCE--HNHRQCSRH-AFCTDYATGFCCHCQSKFY GNGKHCLPEGAPHRVNGKVSGHLHVGHTPVH---FTDVDLHAYIVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGS-ENGFSLAGAAFTHDMEVTFYPGEETVRITQT AEGLDPE------NYLSIKTNIQGQVPYVPANFTAHISPYKELYHYS-DSAVTSTSSRDY SLTF-GAINQTWSYRIHQNITYQV---CRHAPRRPS-FPTTQQL--NVDRVFALYNDEER VLRFAVTN----QIGPVKEDS----------------------------DPTPVNPCYDG SHMCD-TTARCHPGTGVDYTCECASGYQG----DGRN---CVDENECATGFHRCGPNSVC INLPGSYRCECRSGYEFADDRHTCILI--------------------------------- ----------------------------------------------------------TP PANPCEDGSHTCAPAGQARCVHHGGS-TFSCACLPGYAGDGHQCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPAATC--YNTPGSFSCRCQPGYYGDGFQ- CI---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PDST-SSQTPCEQQQR ----HAQAQYAYP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARF----- ---HIPQCD-EQGNFLPLQCHGSTG----------FCWCVDP-DGH-------------- ----EVPGTQTPPGSTPPHCGPS------------------------------------- ------------------------------------------P-------EPTQRP-PTI CERWRENLLEHYGGT-------PRDDQYVPQCDDLGLFIPLQ------------------ -----------------C------HGKSDFCWCVDK-DGREVQGTRSQPGTTPA------ ---CIPTV-APPMVRPTPR-------PDVTP-------PSVG-T---------------- ---FLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHG-SIIVGIDYDCRERMVYWTDVAGR TISRASLELGAEPETIVN-SGLISPEGLAVDHIRRTMYWTDSVLDKIESALLDG-SERKV LFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILIN-TDIGLPNGLTF DPFSKLLCWADAGTKKLECTLPDG--TGRRVIHN----NLKYPFSIVS-YADHFYHTDWR RDGV-VSVNKHSG-QFTDE--YLPE-QRSHLYGITAVYPYCPTG--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_023111456.1 nidogen-2 [Felis catus] MR--------------------------------GDRA---------------------- ------LP---------------------------------------------------- -----PPLLPLLLLLLLSRAAALRP----DELFPY---GQSWGDQLLQEGDDE--SSAAV KLASPLRFYEAQFSYLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS QG--RGQVLYR-EDTSRAVLDLAARYVRSGFPRT----AAHFTPTHTFLVTWKQVGAYEE TTRRAPPSEERNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLE----LPAR VGFCRGEVDDL---KREGPYFSLT-STEQSVKNLYQQSNLGAPGVWAFHIGST----PRL DNIRPATVGGD-LSKGHSAAP---PERSFGLPEVLASDYTEDNL-D----YYDENENEG- ------GVEYTPSEPEE-ALNGHSSVDVSFQSKAESRPMGGGMSPPNSDLASPL----PH LTSSNWPFYPETESATLNPQPKEGRHPWGMDTPDLNVRVESSEQPGTRGPAPSEVEGESL DPSQGTLPPYPENKSINPYTYGGAPPSEADVPPALPEGKV-VLLNYP-LPAHSIPLGRG- RQVLGV-EDVITSNTEVFTYNAADKETCE--RNHGQCSPH-AFCTDYTTGFCCHCQSRFY GNGKHCLPEGVPHRVNGKVSGHLRVGHTPVH---FTDVDLHAYIVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGW-ENGFRLTGATFTHDMEVIFYPGEERVRITQT AEGLDPE------NYLSIKTNIQGQVPYIPANFTAHMAPYKELYHYT-DSAVTSTSSRDY SLIL-GGINQTLSYRIYQNITYQA---CRHAPRHRA-IPKTQQL--NVDRVFALYTDGEG VLRFAVTN----QLGPVEVDS----------------------------TPTPVNPCFDG SHTCD-TKARCHPGTGVDYTCKCASGYQG----DGRS---CVDVNECATGFHHCGPNSVC TNLPGSYSCDCRSGYEFADDHHTCILI--------------------------------- ----------------------------------------------------------AP PPNPCADGSHSCAPADQARCIYHGGS-TFSCTCLPGYTGNGHQCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPSATC--YNTPGSFSCRCLPGYHGDGFQ- CA---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PDPT-SGLKPCERQQR ----SAHAQHTYP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GSRV----- ---HIPQCD-EQGHFLPLQCHGSTG----------FCWCVDP-NGH-------------- ----EVPGTRTPPGSTPPHCGP-------------------------------------- ------------------------------------------A-------EPTRRP-RTV CERWRENLLEHYGGT-------PRDDQYVPQCDDLGHFTPLQ------------------ -----------------C------HGKSDFCWCVDK-DGREVQGTRSQPGTTPA------ ---CIPTV-APPTARPLPR-------PDVTP-------PSVG-T---------------- ---FLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHG-SIVVGIDYDCRERMVYWTDVAGR AISRASLEPGAEPETIIS-SGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDG-SERKA LFHTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLEGENRRILVN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECTLPDG--TGRRVIQN----HLNYPFSIVS-FADHFYHTDWR RDGV-ISVNRDSG-QFTDE--YLPE-QRSHLYGITAVYPYCPTG--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_004010577.3 nidogen-2 [Ovis aries] MR--------------------------------ADRAAGRPA----------------- ------LP---------------------------------------------------- -----PPPLLLMLLLLLSRAAALHP----SELFPY---GQSRGDQLLQEGDDE--SSAAV KLTLSLRFYDAQFSDLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS GG--RGRVLYR-QDTSPAVLGLAANYVRTGFPLS----GAHFTPTHAFLATWEQVGAYEE AKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQ----LPAR VGFCRGEVDDL---NRQGPYFSLT-STEQSVKNLYQHSNLGIPGVWAFHIGST----SPL DNVRPATVGGV-LSKAHPWAP---LGQSFSHAVALEDDYTQDTL-D----EYDENEEE-- -------IEYPPSEPAE-ASNGHSTIDVSLGGR---------ISAPDSDLASPV----PR SASRGGP---ETEASPLDPHTEERRPQGETNAPDLKQRVESSQQPGTRVPAPPETEGESP APPGEAPPPSLEG---------GAGPADQDALPAHPGGEA-ALPNYP-GPDHAPHLGHR- RQVVGV-EDDISSNTEVFTYNAANKETCE--HNHERCSRH-AFCTDYATGFCCHCQSRFY GNGKHCLPEGAPHRVNGKVSGHLLVGHTPVH---FTDVDLHAYVVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGW-ENGFSLTGATFIHDVEVTFYPGEERVRITQT AEGLDPE------NYLSIKTNIQGQVPYIPANFSAHMAPYKELYHHA-DSAVTSTSTRTY SLMS-GAINQTQSYRIHQNITYQV---CRHAPRHWA-VPVTQQL--NVDRVFALYSDEEK VLRFAVTN----QIGPVEGDS----------------------------EPTPVNPCYDG SHTCA-TTARCHPATGVDYTCECASGYQG----DGRS---CVDVNECATGFHRCGPNSVC VNLLGSYRCECRSGYEFADDRHTCISI--------------------------------- ----------------------------------------------------------TP PPNPCENGRHNCAPASQARCIHHGDG-SFSCACLPGYAGDGHRCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPLATC--SNTPGSFSCRCQPGYYGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------P-------EPTQRP-RTV CERWRESLLEHYGGT-------PRDDQYVPQCDDLGHFTPLQ------------------ -----------------C------HGKSDFCWCVDQ-DGREVQGTRSQPGITPA------ ---CIPTV-APPTSRPTPR-------PDVTP-------PPVG-T---------------- ---FLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHG-SIVVGIDYDCRERMVYWTDVAGR TISRASLEPGAEPEMVIN-SGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDG-SERRA LFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECILPDG--TGRRVIQS----NLNYPFNIVS-YADHFYHTDWR RDGV-IAVNRDTG-QFTDE--YLPE-QRSHLYGITAVYPYCP-G--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_011482732.1 nidogen-2 [Oryzias latipes] ------------------------------------------------------------ ----------------------------------------MDRGSL-------------- -----LTVSLLCWSCG--AVTAIRR----ADLFPF---GTSSGDSLLAEGDDE--TSKVL ILPKPFYFYNSQFSLLYVATNGIVSAQDLPME---KQYVDDGFPTDFPVVAPFLADIDTS GG--RGQIYYR-VTETPSVLNRLTWEVSRGFPD------AKFTPTHAVVATWENVAAYEE PSRSSGSSNRVNTFQAVIAYDETDSYVLFLYPEDGLNFFGTRPKESYNVEIE----LPAR VGFSRGEVTYFFFSRSEGPSYSVT-SDEQSVKNLNRVGNTGTPGLWLFHTGHR----YSF DNVIPASVGGP-IVTAPPR--RFVPDTTTPEYEVIY------TL------GPEIH-ED-- -------DEYSLTGRGP-------------------------AASNHFQYLQPGSPEPSY SPPEDSGHQ-----VLLGSEPR---------------------------------YGPEP AGRQYAPPEQPQRVLE-----GGARQGQEQIPQLPLE----VVDLYP-PDRN----TPG- GYVVNVEEDDVHFDTRVIQYTTDNKETCA--RFQQQCSQN-AFCSDYATGFCCHCQPGFY GNGRDCLPEGAPQRVSGKVSGTVSVQSTPVT---LNNIDLHAYIVVGDGRAYSAIS-EVP EPLGWALMPVSPIGELFGWLFALELPNS-QAGFKSTGAKFTRHAEVQFYPGNHRLSILQT GRGLDEH------NLLNVDTVVSGNVPFIPPEAEITVEPFKETYQYY-PSVVTSTSAREI KVVSASRGAESYSLNLKQNITYRE---CRHDNRAS--NPETLQI--TMERVFVMYDKDER ILRYAVTN----KIGPVGADP---------------------------VAPELINPCYSG NHDCD-TTAMCIPQEDQNYECQCATGYGG----DGRN---CYDIDECAEGVSSCGEHSEC LNLPGSHRCLCSRGFEFAYDGRTCV----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------DID-------ECS---------------- --------------------------SSPCHINARC--INELGSFQCLCQPGFTGDGFF- CSQQE------------------------------------------------------- ----------------------------------------------DLPARPKTRCEHHR ESVQRTTEE--------------------------------------------------- -----------------------------GAPLLGVYVPQCDESGKYLPQQCHDSTGYCW CVDSTGQERTGTRTPPGSALVDCSRT---------------------------------- -DEQPHY-----------------------------------------------KTRCE- RHREHVLASEREDR------------PSVGAYVPQCDQNGEYVPQQCHTS---TGYCWCV D-GMGQERSGT--------------------RSAPGSPSMDCSKPDEALQPKTPCERLRE S--VLASSAGGRPLAGAYA----------------------------------------- ---------------------------------------PQCDEDGHYVPRQCHGSSGYC ----WCVDSSGQERPGTRTSPGAPSVDCSRA---E------------------------- ----------------------------------------------------EPEAPKTE CELLRERAMAS------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------SPEAVPAAGR----- ---FVPQCD-AEGRYLSQQCHGSTG----------HCWCVDS-RGQ-------------- ----ERPGTRTPPGVAQVDCYQR------------------------------------- ------------------------------------------PEP----EPPYTRP-ESV CERWRASLMEHYGGK-------PQPQQYLPQCRSDGEFSPVQ------------------ -----------------C------YGETTYCWCVDQ-DGREIDGTRSHDAVKPA------ ---CLSSV-APPTVLPLPR-------PDVTP-------PTNADV---------------- ---TLLYAQGQKIDALPLNGTKLHANGSKTLLTLHG-SIVVGIAYDCRENQVYWTDLSAR TINRASLVSGSEPEILIS-SNLESPEGLAVDVQRRLMFWVDSSPDNIEVANLDG-SERRT LFDTDLVNPRAIIVVSSKGTLYWTDWNREAPKIECSTVNGQNRRVVVS-DGVGLPNALAY DHATDQVCWADAGTKRLECVSPNG--SGRRVIHR----NLNYPFSMVY-YRDHFYYTDWR RDGV-IAVNRDSN-KLTEE--YLPD-QRSHLYGIAVATNHCLQG--SH------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_013223751.1 nidogen-2 isoform X1 [Columba livia] MA--------------------------------------REGH---------------- ------------------------------------------------------------ ---------------VVSRLSTLCPRG-----------GTCWG----THGRG---TSAAP EHLVPL--------SLQVGTNGVISTQDFPRE---TQYVDDDFPTDFPVIAPFLADLDTS GD--RGNIYYR-QDDSPDVLHQAAGYIQAGFPHI----AGSFMPTNAFIATWEDVGAYQE LSQDTKPSQKLNTFQAVVAYDDEDTYAIFLYPKGGLQFLGTRPKESYNVQLE----LPAR VGFSWGDGDDP---KRDGLFHSLA-SSERALRLLERESNTGIPGVWVFHVGSV----SPL EHVEPGGGGGASPGVPQSPEPHVPDTAGYTHALYSHADHVATNL---------------- ------------------------------------------PVRHGSAAMSPH----PD HGHHA---------------------------------------------------PTLL GIVPRGLPVSPSG--------------QERSRRLHLDGDVGTQQSYS---PNPSSYSSG- HHGVGV-EEDVHFNPDVFTYSAASKETCA--RHHGRCSPH-AFCTDYATGVCCHCQATYY GNGRQCLPEGAVHRLNGKVSGSLMVGRMSVS---FQDVDLHAYIVGSDGRAYTAIT-GVP QPAGRALLPLLPLGGLFAWLFALEDPGS-ENGFSITGAEFTQSLEVTFYPGGETVRVTQT AEGLGPD------NYLSLKTHIQGQVPFLPENVTVHITPYKELYHYS-SSVVTSSAQREY VLAA-GTANQTLSYRLRQNITFSG---CPHTR-----LPAQQRL--SVARAFALYDGHEH VLRYALAA----RIGSAPDDA----------------------------ENPLVNPCHDG THRCE-APARCQPGTGMEYTCECVAGYRR----DGWG---CRDVDECAEGLSQCGPFAIC LNAPGSYRCECRSGYQPAGDGQMCVPL--------------------------------- ----------------------------------------------------------VP ATDPCEDGSHPCAPPDRARCLSHAGG-HPTCECLPGYAGDGIYCS--------------- -------------------------------DVD-------ECA---------------- --------------------------ENPCHPAATC--YNTPGSFSCQCPPGYEGDGFQ- CVHAAGS----------------------------------------------------- -------------------------------------------------TQRLSPCQHE- ------------------------------------------------------------ ---------------------------------------------QLYPRE--------- ------------------------------------------------------------ ------------------------------------------------------------ --------VPSGPS------------PVGDRHMPQCDEEGGYRPLQCHSS---TGHCWCV D-TAGQEIAGT--------------------RTAPGSTPPRCGNPEST-QRLTPCQHERL ----YPRGVPPGP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------SPVGDR----- ---HVPQCD-EDGGYRPLQCHSSTG----------HCWCVDA-AGQ-------------- ----EIAGTRTAPGSTPPRCGN-------------------------------------- ------------------------------------------P-------EPTERP-RSM CERWRQSLLEHYGGS-------PRRDQYVPQCEAGGEFTPLQ------------------ -----------------C------HGDSGYCWCVDE-SGREIPGTRSEPGSTPP------ ---CLPSV-APPSVRPSPR-------PDVSP-------PATG-T---------------- ---FLLYAQGQQIGYLPLNGTRLQKEAAKTLLSLHG-SIVVGIGYDCREKTIYWTDVAGR TISRASLEPGAEPETIIS-SGLISPEGLAVDHLRRAIFWTDSGLDKIERARLDG-SERQV LFDTELVNPRAIAVDPVRGNLYWTDWNREAPKIETSTVNGANRRVLVN-RDIGLPNGLTF DPFSKLLCWADAGTKHLECTFPDG--TGRRIIQN----NLNYPFSIIS-YANHFYHTDWR RDGV-IAIDKETG-SFTDE--YLPE-QRSHLYGITAVYPYCPGA--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_017909832.1 PREDICTED: nidogen-2 [Capra hircus] MR--------------------------------ADRAAGRPA----------------- ------LP---------------------------------------------------- -----LPPLLLLLLLLLSRAAALHP----SELFPY---GQSRGDQLLQEGDDE--SSAAV KLTLSLRFYDAQFSDLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS GG--RGRVLYR-QDTSPAVLGLAANYVRTGFPLS----GAHFTPTHAFLATWEQVGAYEE AKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQ----LPAR VGFCRGEVDDL---NRQGPYFSLT-STEQSVKNLYQHSNLGIPGVWAFHIGST----SPL DNVRPATVGGV-LSKARPWAP---LGQSFSPAVALEDDYTQDTL-D----EYDENEEE-- -------IEYPPSEPAE-ASNGHSAIDVSLRGR---------ISAPDSDLASPV----PR SASRGGP---ETEASPLDPHAEERRPQGETNAPDLKQRVESSQQPGTRVPAPPETEGESP APPREAPPPSLEG---------GAGPADQDALPAHPGGEA-ALPNYP-GPDHAPHLGHR- RQVVGV-EDDISSNTEVFTYNAANKETCE--HNHERCSRH-AFCTDYATGFCCHCQSRFY GNGKHCLPEGAPHRVNGKVSGHLLVGHTPVH---FTDVDLHAYVVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGW-ENGFSLTGATFIHDAEVTFLPGEERVRITQT AEGLDPE------NYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYA-DSAVTSTSTRTY SLMS-GAINQTQSYRIHQNITYQV---CRHAPRHWA-VPVTQQL--NVDRVFALYSDEEK VLRFAVTN----QIGPVEGDS----------------------------EPTPVNPCYDG SHTCA-TTARCHPATGVDYTCECASGYQG----DGRS---CVDVNECATGFHRCGPNSVC VNLLGSYRCECRSGYEFADDRHTCISI--------------------------------- ----------------------------------------------------------TP PPNPCENGRHNCAPASQARCIHHGDG-SFSCACLPGYAGDGHRCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPLATC--SNTPGSFSCRCQPGYYGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------P-------EPTQRP-RTV CERWRESLLEHYGGT-------PRDDQYVPQCDDLGHFTPLQ------------------ -----------------C------HGKSDFCWCVDQ-DGREVQGTRSQPGITPA------ ---CIPTV-APPTIRPTPR-------PDVTP-------PPVG-T---------------- ---FLLYAQGQQIGHLPLNGTRLQKDTAKTLLSLHG-SIVVGIDYDCRERMVYWTDVAGR TISRASLEPGAEPEMVIN-SGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDG-SERRV LFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECIFPDG--TGRRVIQN----NLNYPFNIVS-YADHFYHTDWR RDGV-IAVNRDTG-QFTDE--YLPE-QRSHLYGITAVYPYCP-G--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_014375969.1 nidogen-2 [Alligator sinensis] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TDVNKT LG--TRR---------RAVLSRAAGYIRAGFPS------TAFAPTRAVVATWEDVGAYEE VSRDAEPSRQRNTFQAVLAYDHADAYALFLYPDDGIQFFGTRPKESYHIQLE----LPAR VGFSRGETDP----RRENLHYSVA-SSEQGLKNLYQSSNVLTPGVWVFHIGSA----SPL ENIVPAGAARQLLGGALPTGP-----ESASHHATAEHDYPDGAF-AI--FSYDENEED-- ------NEEFPFVEPTEVVAEDYDELGISLHTDINLQDR----VQEGLEFASKL----PM PASSHLPSSPEARPVPSQE------------------------------PSSLETDEDLL ELVSVESPTYRQREDVQPYPDGGAIPAETDVHLGYPEGEV-VLQSYP---DSPLPFPRG- RHIVGV-DEDISFNTDVFTYSAASQETCE--QHHGLCSPH-AFCTDYATGFCCHCQTKFY GNGRHCLPEGAAHRLNGKVSGNLLVGRTPVH---FADVDLHAYVVGNDGRAYTAIS-RIP QLAARALMPLTPIGGLFGWLFALEKPGY-ENGFSITGAEFTHSLEATFYPGEETVHITQT AEGLGLE------NYLSLRTRIQGRVPYIPENFTVHIAPYKELYYYS-SSAVTSTSHREY SLLF-GHHNQTLSYRLHQNVTFRD---CPHARARRT-MPATQQL--SVERVFALYNEEEQ VLRYAVTN----QIGSAEGDS----------------------------DTAVVNPCYDG THVCD-TTARCQPGAGLQYSCECTAGYCG----DGQD---CMDIDECAEGESRCGPFSVC LNSLGSYRCECQHGYRLTDDRRTCVLA--------------------------------- ----------------------------------------------------------AP PPDPCAAGRHSCAAADQARCIPRGGG-AFSCECLPGYTGDGHNCS--------------- -------------------------------DVN-------ECT---------------- --------------------------QGRCHPAATC--LNTPGSFSCQCRPGYDGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PANL-QRLTPCEHERL ----YSQPE--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------PGH----- ---HIPVCD-DQGNYHPLQCHSSTG----------FCWCVDE-AGQ-------------- ----EITGTRTPPSSTPPRCGE-------------------------------------- ------------------------------------------P-------EPTVRP-QTM CERWRQSLLDHYGGR-------PREDQYVPQCDTAGSFSPLQ------------------ -----------------C------HGNSGFCWCVDE-HGREIHGTRSEPGTAPP------ ---CLPSV-APPTVQPSPR-------PDVSP-------PAAG-T---------------- ---FLLYAQGHQIGYLPLNGTRLQKEAAKTLLALHG-SIVVGIDYDCRGKMVYWTDVAGR TVNRASLEPGAEPETVIN-SGLMSPEGLVVDHLRRAMFWTDSGLDKIERANLDG-SQRRA LFSTDLVNPRAITVDPIRGNLYWTDWNREAPKIETSTVEGANRRILVN-EDIGLPNGLTF DPFSKLLCWADAGTKKLECMFPDG--TGRHVVQN----NLNYPFSIVS-YANHFYHTDWR RDGV-IAVNKDTG-SLTEE--YLPE-QRSHLYGITAVYPYCPGV--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_015807982.1 PREDICTED: nidogen-2 isoform X1 [Nothobranchius furzeri] MR---------PVTNQVEPNI--LDPAP-APLLTSSGAAGPSSD---------------- ----CSPPFLLLPCVLVPR-TQSSLLGVD-----------MDGGSV-------------- -----LAAALLYWSCGVCVVSALHR----TDLVSY---GALSGDLILAEGDDE--TSRVL TLPRPLYFYDTPFHQLYVATNGIISAQDLPME---KQYVDDGFPTDFPVVAPFLADIDTS GG--RGHIYYR-VTETPSVLNRVAQEVRRGFPD------AKFAPTHAVVATWENVAAYED QTQGTELSNKVNTFQAVIGYDETDSYTLFLYPEDGLNFFGTQPKELYNVKIE----LPAR VGFSRGEVTFFIFSRSEGPFYSVT-TDEKSVKRLSQVGNTGIPGVWLFHTGNR----HSF ENIIPAAIGGL-LSTLPPEGHALSPDTTTPEYG----DYPDNTF------ESESPEEV-- -------DGYTATGKDL-----------EFQPV---------PDGGDSGSLQPGSPGSTP PSSEDSDHQ-----VTYN--------------------------------------GEEG EEGQYVPPNHPERR---------AQQLQEQKPQLPLE----VVEVNP-SPENEPPLSPG- GYVVSVDEEDVDFDTGVIQYTTENKETCA--RFQQQCSQN-AICSDYATGFCCHCRPGFY GNGRQCLPDGAPQRVSGKVSGTVTVGSFPIV---LDNIDLHAYIVVGDGRAYTAIS-QVP EPVGWALMPVSPVGELFGWLFALELPNS-QAGFKTTGAEFTRHAEVLFNPGNQRLSIIQT GSGLDEH------NHLRVETIVSGHVPLLPPGAEVTVQPFKETYQYY-PSVITSSSVREF VVVSAERGSQSYTFHLKQNITYRD---CRHDNRA---TPETLQI--TMERVFVMYVKEER ILRYAITN----KISPVGAGS----------------------------DDELLNPCYVG NHDCD-TTAQCIPLEGQAFKCQCATGYTG----DGHN---CYDIDECAEGSDLCGDHSQC LNLPGSHRCQCWEGFEMAFDGRNCV----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------DID-------ECS---------------- --------------------------SSPCHINARC--INDLGSFRCHCQPGFHGDGFY- CALQEGR---------------PKSQCEQHRDSLQSGGHGD---G-----AHIPQCDSDG RYRSLQCHGS---NGYCWCVDDRGQERPGTRTSPGTTPKDCD--KPDDPQRPKTHCEHHR DSIQTTSPDGRPLLGAYAPQCDEHGHYKPQQCLGSTGYCWCVDSRGQERPGTRTAPGTPH VDCDKP---DRPKTHCERHRDSVQTTSPDGHPLLGAYVPQCDEHGHYQPQQCHGSTGHCW CVDDKGQERPGTRTPPGTPHVDCRRP---EGPKTHCELHRDRVQHTGPDGHPIVGAHIPQ CDEHGHYQPQQCHGSTGHCWCVDDRGQERPGTRTPPGTPHV--DCRR---PERPKTHCE- LHRDRVQHTGPDGH------------PIVGAHIPQCDEHGHYQPQQCHGS---TGHCWCV D-DKGQERPGT--------------------RTPPGTPHVDCRRPDDPQRPKTHCEHHRD S--VQTTSPDGHPLVGAYVPQCDEHGHYKAQQCHGSTGHCWCVDDKGQERPGTRTPPGTP HVDCRR---PKRPKTHCELHRDRVQQTGPDGHPIVGAHIPQCDEHGHYQPQQCHGSTGHC ----WCVDDKGQERPGTRTSPGTPHVDCRRP---ERPKTHCELHRDRVQHTGPDGHPIVG AHIPQCDEHGHYQPQQCHGSTGHCWCVDDKGQERPGTRTPPGTPHVDCR---RPERPKTH CELHRDRVQHTGPDGHPIVGAHIPQCDEHGHYQPQQCHGSTGHCWCVDDKGQERPGTRTP PGTPHVDCRRPEHPKTHCEQHRDRVQVTSPGGHPIEGTYVPQCDEHGHYQPQQCHGSTGQ CWCVDDRGQERPGTRTPPGTPRVDCSRSERPKTSCEQHKERAEATSSEGYPIAGA----- ---YVPQCD-AKGQYIPLQCFGSTG----------HCWCVDP-SGQ-------------- ----ERPGTRTPPGTPPKDCAKPG---RPKTPCEQHRDRVQATTREGYPVVGGYEPRCDA EGQYLPQQCHGSNGHCWCVDSSGQERPGTRTPPDTPPKDCSKP-------ASTSRP-ESV CERWRASLMEHYGGK-------PDPQQYLPQCEPAGEFSPVQ------------------ -----------------C------YGHTTYCWCVDE-NGREVPGTRSHDVVKPA------ ---CLPSV-TPPTARPLPR-------PNVTP-------PPNADV---------------- ---TLLYAQGQKIGALPLNGTRLDSSRSRTLLTLHG-SIVVGIAYDCKENQVYWTDLSAR TINRASMVSGAEPEILIN-SNLVSPEGLAVDVKRRLMFWVDSSPDVIESANLDG-SRRRI LFDTDLVNPRAIIVVSSTGTLYWTDWNREAPKIESSSVDGLNRRVVVS-DGVGLPNALTY DSSSGQVCWADAGTKRLECISPNG--SGRRVIHP----TLNYPFSMVY-YRNHFYYTDWR RDGV-IAVSKDSS-KFTDE--YLPE-QRSHLYGVTIATTYCLPG--NH------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_030857550.1 nidogen-2 isoform X1 [Gorilla gorilla gorilla] ME--------------------------------GDRVAGRPV----------------- ------LS---------------------------------------------------- -----SLPVLLLLPLLMSRAAALHP----DELFPH---GESWGDQLLQEGDDE--SSAVV KLENPLHFYEARFSNLYVGTNGIISTQDFPRE---TQYVDYDFPTDFPAIAPFLADIDTS HG--RGRVLYR-EDTSPAVLGLAARYVLAGFPRS-----ARFTPTHAFLATWEQVGAYEE VKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQ----LPAR VGFCRGEADDL---KSEGPYFSLT-STEQSVKNLYQLSNLGIPGVWAFHIGST----SPL DNVRPAAV-GD-LSAAHSSVP---LGRSFSHATALESDYNEDNL-D----YYDVNEEE-- -------AEYLPGEPEE-ALNGHSSIDVSFQSKVDTKPLEGRISPPDSHLSSPL-----H PTPTYWPFYPETESSTLDPHTKEGTSLGEVEGPDLKGQVEPWDERGTRSPAPPEVDRDSL APSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEI-VLRNYP-ASGHTTPLSRG- TYEVGL-EDNIGSNTEVFTYNAANKETCE--HNHRQCSRH-AFCTDYATGFCCHCQSKFY GSGKHCLPEGAPHRVNGKVSGHLHVGLTPVH---FTDVDLHAYIVGNDGRAYTAIS-DIP QPAAQALLPLTPIGGLFGWLFALEKPGS-ENGFSLAGAAFTHDMEVTFYPGEETVRITQT AEGLDPE------NYLSIKTNIQGQVPYVPANFTAHISPYKELYHYS-DSTVTSTSSRDY SLTF-GAINQTWSYRIHQNVTYQV---CRHAPRRPS-FPTTQQL--NVDRVFALYNDEER VLRFAVTN----QIGPVKEDS----------------------------DPTPVNPCYDG SHMCD-TTARCHPGTGVDYTCECASGYQG----DGRN---CVDENECATGFHRCGPNSVC INLPGSYRCECRSGYEFADDRHTCILI--------------------------------- ----------------------------------------------------------TP PANPCEDGSHTCAPAGQARCVHHGGS-TFSCACLPGYAGDGHQCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPAATC--YNTPGSFSCRCQPGYYGDGFQ- CI---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PDST-SSLTPCEQQQR ----HAQAQYAYP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARF----- ---HIPQCD-EQGNFLPLQCHGSTG----------FCWCVDP-DGH-------------- ----EVPGTQTPPGSTPPHCGPS------------------------------------- ------------------------------------------P-------EPTQRP-PTI CERWRENLLEHYGGT-------PRDDQYVPQCDDLGHFIPLQ------------------ -----------------C------HGKSDFCWCVDK-DGREVQGTRSQPGTTPA------ ---CIPTV-APPMVRPTPR-------PDVTP-------PSVG-T---------------- ---FLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHG-SIIVGIDYDCRERMVYWTDVAGR TISRASLELGAEPETIVN-SGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDG-SERKV LFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILIN-TDIGLPNGLTF DPFSKLLCWADAGTKKLECTLPDG--TGRRVIQN----NLKYPFSIVS-YADHFYHTDWR RDGV-VSVNKHSG-QFTDE--YLPE-QRSHLYGITAVYPYCPTG--KKYALEKYALGCSF KL-----------------------AG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_030265795.1 nidogen-2 isoform X1 [Sparus aurata] ------------------------------------------------------------ ----------------------------------------MERGRL-------------- -----LAVCVLCWSCSVRVVTAIQR----ADMFPY---GSLSGDMILAEGDDE--TSRVL SLPRPVYFYDSLFSQLYVATNGIVSAQDLPME---KQYVDDGFPTDFPVVAPFLADIDTS GG--RGQIYYR-VTETPSVLNRVAQEVHRGFPD------AKFTPTHVVVATWENVAAYEE PTRTSGPSNKFNTFQAVIGYDEVDSYVLFLYPEGGLNFFGTRPKESYNVEIE----LPAR VGFSRGEVTYLIFSRTEGPHYSVT-SDEQSVKNLYQVGNTGIPGVWLFHTGNR----YSF DNIVPASVGGL-LATPPTRGHGLSLDTTTPDYPEFE-EYPDNTF------DPDSQDEE-- -------DDYPLTGGDA-----------EFQPA---------PASDHSEAPQPASPDAPS SPSEDVPH------------------------------------------------GSQP SNRQYAPPNPPEAAP------------EEQQPQVPLE----VVDVYP-PHRNEPPLSPG- GHVVSVDEDDVDFDTGVIQYTTENKETCA--RFQQQCSQN-AFCSDYATGYCCHCRPGFY GNGRHCLPEGAPQRVSGKVSGTVTVGSTPVD---LNNIDLHAYIVVGDGRAYTAIS-EVP EPVGWALMPVAPIGELFGWLFALELPNS-QAGFKITGAEFTRRAEVIFYPGNQRLSIIQT GRGLDDH------NHLTVDTVLSGSVPFLPPGAEVTMDPFKETYQYY-PSVATSTSVREY SVVSADRGSESFSFQLKQNITYRD---CRHDSSTT--ALETLQI--TMERVFVMYVKEER ILRYAITN----KISPVGVEP---------------------------TGPELVNPCYAG THDCD-TTAQCIPQEGQAFRCQCATGYRG----DGRN---CYDIDECAEGLSTCGAHAQC MNLPGSHRCQCQSGFEFGFDGRTCV----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------DVD-------ECS---------------- --------------------------SSPCHVDARC--INGLGSFQCQCQAGFYGDGFY- CSQQEGQT------------VRPKSHCEQHRDSLQSGGDGRPSVG-----AFIPQCDSDG RYRLLQCHGS---TGHCWCVDSRGQERAGTRTPPGTAPKDCD--RPDEPERPKTHCEHYR DSVQTTSPEGYPITGAYVPQCDANGQYIPLQCHGSSGHCWCVDSNGQERVGTRTAPGTTP IDCDKPEEQERVKTQCEHHRDSVQTTSPEGYPIVGAYVPQCDANGQYRSLQCHGSTGHCW CVDTRGQERAGTRTPPGTATKDCDRPDEPERPKTHCEHHRESVQTTGPEGYPIVGAYVPQ CDANGLYTPLQCHGSSGHCWCMDSRGQERAGTRTLPGAPPT--DCDKPDEPERPKTHCE- HHRDSVETTGPEGY------------PIVGAYVPQCDANGQYRSLQCHGS---SGHCWCV D-SRGQERAGT--------------------RTPPGTAPKDCDKPDEPERPKTHCEHHRD S--AQTTSPEGYPIPGAFVPQCDANGQYASQQCHGSSGHCWCVDRTGQERAGTRTPPGTA PIDCNKQDEPEHPKTHCEQHRERAQATSSDGYPIVGAYVPQCDANGQYRPLQCHSSSGHC ----WCVDRTGQERAGTRTPPGTATKDCDRPDEPEHPKTHCEHHRERAQATSSDGYPIVG AYVPQCDANGQYRPLQCHSSSGHCWCVDRKGQERAGTRTPPGTATKDCDRPDEPEHPKTH CEQHRERAQATSSDGYPIVGAYVPQCDANGQYRPLQCHSSSGHCWCVDRTGKERAGTRTP PGTATKDCDRPDEP---------------------------------------------- ----------------------------EHPKTHCEHHRERAQATSSDGYPIVGA----- ---YVPQCD-ANGQYTPLQCHSSSG----------HCWCVDR-TGQ-------------- ----ERAGTRTPPGTAPKDCDRPDEPERPKTQCEQHRDSVQTTSPEGYPLFGAFVPQCDP NGQYSAQQCHSSTGHCWCVDGRGEERAGTRTTAGIPPVNCDESVP----VVPTQRL-ESV CERWRSSLIEHYGGK-------PEPQQYLPQCEPDGQFSPVQ------------------ -----------------C------YGETTYCWCVDQ-DGREVPGTRSHDVVKPA------ ---CLPSA-APPTVRPLPR-------PDVTP-------PTNADI---------------- ---TLLYAQGQKIGALPLNGTRLDATRAKTLLTLHG-SIVVGIAYDCRENRVYWTDLSAR TINRASMAPGAEPEILIN-TNLVSPEGLAVDVKRRLIFWVDSNPDMIESANLDG-SGRRT LFDTDLVNPRAIIVVSSSGTLFWTDWNREAPKIESSSVDGQNRRVVVS-DGVGLPNALTF DSSSGQVCWADAGTKRLECVSPDG--SGRRVIHS----SLNYPFSMVY-YRNHFYYTDWR RDGV-IVVSKESS-QFTDE--YLPD-QRSHLYGIAIATSQCLSG--TH------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_040188888.1 nidogen-2 [Rana temporaria] M----------------------------------------------------------- ------------------------------------------------------------ --VSRVLRILHWHCLLLGFSAAISR----QELFPY---GESRGDRLLPDGDDE--TSEVV TLTQPILFYEADFKELYVGTNGIISTQDFPRE---TQYVDDGFPTDFPVIAPFLSDIDTS NG--KGKIYYR-QDNSPDILSTVARQVDRGFPQ------AAFSPTNVFMVTWDNVGAYEE VTRHAEPSNKLNTFQAVLAYDDSDTYAIFLYPEHGLQFFGTRPKESYNVHLD----LPAR VGFSRGDSEML---KKEAPFYSVT-SSEQSVKNLYQTSNVGVPGVWVFHIGSL----SEI DNVIPAKVPHH-HPQQR-FVPLINSHNDFPEQQQQQQLENQFNGEN----NYEDNYED-- -------EDYPAGQTTEAPTTDSAVLNPDRTHDFI-------DAEDHATLYTPN---NPL PPSQEEPSW-----TPYNPDE---------------PLVEPEIQRSE-----SRVLGNIP SYETQEEPSESVSEDF----------NNVTPNPVDPQRSD-V--------------YRS- NRFYGN-EEVGGLDTDVLTFNPVSRETCD--RKPGYCSPY-AFCTDYATGFCCHCQDSYY GNGVHCLPKGAPHRVNGKVSGNLLVGQRPVT---FDGIDMHAYIVVNDGRAYTAIS-QVP EPASWSLTPLTAIGGLFGWLFALEKPGH-QNGFSITGAKFVHNLEAVFSPGEEVIHVTQT ADGFDSD------NYIHVRTTIKGKIPYIPETSTVQIAPYYEIYQHS-GSVVTSTAYREY TVTSQSGDVQKFSYRLKQNITYQE---CGHAQKY---PPTAQKL--SVDRVFAMHNKDEK VLRFAITS----HIGSLHDSS---------------------------QEPTQGNPCFDG THQCD-TRAQCQPATGLNYSCVCASGYRG----DGRD---CTDYDECEDQLDNCGQNTRC VNLPGSFRCECVPGYVFSADGQNCILG--------------------------------- ----------------------------------------------------------SS FGNPCEDGTHSCD-LTTSQCVPRGDG-VFTCECFPGYTRSGQSCI--------------- -------------------------------DVD-------ECA---------------- --------------------------ERRCHPDATC--ANVPGSFSCRCNPGFTGDGFQ- CTQA-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PEEP-RPSTPCLEKRH ----AAQPRGPRP----------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------PLIGA----- ---FLPECD-EEGNYVPLQCHGSTG----------HCWCVDR-NGN-------------- ----EIEGTRRPAGSGRPQCGI-------------------------------------- ------------------------------------------P-------EPTQRP-QTM CERWKQSLVDHYGGS-------PSAEHYIPQCDAYGEFSPLQ------------------ -----------------C------HGNSGYCWCVDK-DGREIEGSRTQPGMTPA------ ---CLPSV-APPTVRPTPR-------PDVTP-------PTSG-T---------------- ---YLLYAQGQQIGYLPLDGVKFRKDKARTLLALHG-SIVVGIDYDCQEKKVYWTDVSGR TISRAGLEPGAEPEVLIS-TDLMSPEGLAIDYLRKTMFWTDSGTDKIESARLDG-TFRKT LFDTNLVNPRAITVDAVRGNLYWTDWNREAPKIETSYVDGSNRRILVN-DNIGLPNGLTF DPFSKQICWADAGTKKLECILSDG--SGRRVIQS----NLNYPFSVVG-FANHFYHTDWR RDGV-ISINKENG-QITEE--YLPE-QRSHLYGITAIYPYCPSG--KK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >KYO47226.1 nidogen-1 [Alligator mississippiensis] M----------------------------------------------------------- ------------------------------------------------------------ ----------------LHRCRRGGM----PRLFPH---GPARGDRALPPGDDE--GS-AL PLAPLLPFYGLRLARLHVGTNGLLSGQDFPRE---TQYVDDDLPTDFPAIAPFLADLDTS GG--RGQIYYR-QDGASDVLSRAAGYIRAGFPS------AAFAPTHAVVATWEDVAAYEA VSRDAEPSRQRNTFQAVLAYDHADAYALFLYPDDGIQFFGTRPKESYHIQLE----LPAR VGFSRGETDP----GRENLHYSVA-SSEQGLKNLYQSSNVLTPGVWVFHIGSA----SPL ENIVPAGAGRQLLGGALPTAP-----ESVSRHATAEHDYPDGAF-AI--FSYDENEED-- ------NEEFPFVEPTEVVAEDYDELGISLHTDINLQDR--------------------- -------------------------------------------------PSSLETDEDLL ELVSVESPTYRQREDVQPYPDGGAVPAETDVHLGYPEGEV-VLQSYP---DSPLPFPRG- RHIVGV-DEDVSFNTDVFTYSAASQETCE--QHHGLCSPH-AFCTDYATGFCCHCQTKFY GNGRHCLPEGAAHRLNGKVSGNLLVGRTPVH---FADVDLHAYVVGNDGRAYTAIS-RIP QLAARALMPLTPIGGLFGWLFALEKPGY-ENGFSITGAEFTHSLEATFYPGKETVHITQT AEGLGLE------NYLSLRTHIQGRVPYIPENFTVHIAPYKELYYYS-SSAVTSMSHREY SLLF-GHHNQTLSYRLHQNVTFQD---CPHARARRT-MPATQQL--SVERVFALYNEEEQ VLRYAVTN----QIGSAEGDS----------------------------DTAIVNPCYDG THVCD-TTARCQPGAGLQYSCECTAGYRG----DGQD---CVDIDECAEGESRCGPFSVC LNSLGSYRCECQHGYHLADDRHTCVLA--------------------------------- ----------------------------------------------------------AP PPDPCAAGRHSCAAADQARCIPRGGG-AFSCECLPGYTGDGHNCS--------------- -------------------------------DVN-------ECT---------------- --------------------------QDRCHPAATC--LNTPGSFSCQCRPGYDGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PANL-QRLTPCEHERL ----YSQPD--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------------PGH----- ---HIPVCD-DQGNYQPLQCHSSTG----------FCWCVDE-AGQ-------------- ----EIAGTRTPPGSTPPRCGE-------------------------------------- ------------------------------------------P-------EPTARP-QTM CERWRQSLLDHYGGR-------PREDQYVPQCDAAGSFSPLQ------------------ -----------------C------HGNSGFCWCVDE-HGREIHGTRSEPGTAPP------ ---CLPSV-APPTVQPSPR-------PDVSP-------PAVG-T---------------- ---FLLYAQGHQIGYLPLNGTRLQKEAAKTLLALHG-SIVVGIDYDCRGKMVYWTDVAGR TVNRASLEPGAEPETVIN-SGLMSPEGLVVDHLRRAMFWTDSGLDKIERANLDG-SQRRA LFSTDLVNPRAITVDPIRGNLYWTDWNREAPKIETSTVEGANRRILVN-EDIGLPNGLTF DPFSKLLCWADAGTKKLECTFPDG--TGRHVVQN----NLNYPFSIVS-YANHFYHTDWR RDGV-IAVNKDTG-SLTEE--YLPE-QRSHLYGITAVYPYCPGA--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_043327612.1 nidogen-2 [Cervus canadensis] MR--------------------------------GDPAAGRPA----------------- ------LP---------------------------------------------------- ------PP-LLLMLLLLSRAAALHP----SELFPY---GQSRGDQLLQEGDDE--SSAAV KLTLSLRFYDAQFSDLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS GG--RGRVLFR-QDTSPAVLGLAASYVRAGFPLS----GAHFTPTHAFLATWEQVGAYEE AKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQ----LPAR VGFCRGEVDDL---NRQGPYFSLT-STEQSVKNLYQHSNLGIPGVWAFHIGST----SSL DNVRPATVGGD-LSKARPSAP---LGQSFSHAVALEDDYTQDPL-D----DYDENEEE-- -------IEYPPSEPAE-ASNGYSSVDVSLRGR---------ISAPDSDLASPV----PR SASQGGP---ESESSPLDPHTKERRPQGETDASDLKGQVESSEQPGTRVPAPPETEGESP APPEVAPPPSPEG---------GAGPADQDALPAHPGGEA-ALPNYP-GPDHTPHLGHR- RQVVGV-EDDISSNTEVFTYNAANKETCE--HNHERCSRH-AFCTDYATGFCCHCQSRFY GNGKHCLPEGAPHRVNGKVSGHLLVGHTPVH---FTDVDLHAYVVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGW-ENGFSLTGATFIHDVEVTFYPGEERVRITQT AEGLDPE------NYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYA-DSAVTSTSTRAY SLMS-GAINQTRSYRIHQNITYQV---CRHAPRHWA-VPITQQL--NVDRVFALYSDEEK VLRFAVTN----QIGPVEGGS----------------------------EPTPVSPCYDG SHTCA-TTARCHPATGVAYTCECASGYQG----DGRS---CVDVDECATGFHRCGPNSVC VNLLGSYRCECRSGYEFADDRHTCILI--------------------------------- ----------------------------------------------------------TP PPDPCEDGRHNCAPASQARCIHHGDG-SFSCACLPGYAGDGHRCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPSATC--SNTPGSFSCRCQPGYYGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------P-------EPTQRP-RTV CERWRESLLEHYGGT-------PRDDQYVPQCDGLGHFTPLQ------------------ -----------------C------HGKSDFCWCVDQ-DGREVQGTRSQPGITPA------ ---CIPTV-APPTIRPTPR-------PDVTP-------PPVG-T---------------- ---FLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHG-SIVVGIDYDCRERMVYWTDVAGR TISRASLEPGAEPETVIN-SGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDG-SERRA LFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECILPDG--TGRRVIQN----NLNYPFNIVS-YADHFYHTDWR RDGV-IAVNRDTS-QFTDE--YLPE-QRSHLYGITAVYPYCP-G--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >KAF4017381.1 hypothetical protein G4228_009148 [Cervus hanglu yarkandensis] ------------------------------------------------------------ ------------------------------------------------------------ ------------MLLLLSRASALHP----SELFPY---GQSRGDQLLQEGDDE--SSAAV KLTLSLRFYDAQFSDLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS GG--RGRVLFR-QDTSPAVLGLAASYVRAGFPLS----GAHFTPTHAFLATWEQVGAYEE AKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQ----LPAR VGFCRGEVDDL---NRQGPYFSLT-STEQSVKNLYQHSNLGIPGVWAFHIGST----SSL DNVRPATVGGD-LSKARPSAP---LGQSFSHAVALEDDYTQDPL-D----DYDENEEE-- -------IEYPPSEPAE-ASNGYSSVDVSLRGR---------ISAPDSDLASPV----PR SASQGGP---ESESSPLDPHTKERRPQGETDASDLKGQVESSEQPGTRVPAPPETEGESP APPEVAPPPSPEG---------GAGPADQDALPAHPGGEA-ALPNYP-GPDHAPHLGHR- RQVVGV-EDDISSNTEVFTYNAANKETCE--HNHERCSRH-AFCTDYATGFCCHCQSRFY GNGKHCLPEGAPHRVNGKVSGHLLVGHTPVH---FTDVDLHAYVVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGW-ENGFSLTGATFIHDVEVTFYPGEERVRITQT AEGLDPE------NYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYA-DSAVTSTSTRTY SLMS-GAINQTRSYRIHQNITYQV---CRHAPRHWA-VPITQQL--NVDRVFALYSDEEK VLRFAVTN----QIGPVEGGS----------------------------QPTPVSPCYDG SHTCA-TTARCHPATGVAYTCECASGYQG----DGRS---CVDVDECATGFHRCGPNSVC VNLLGSYRCECRSGYEFADDRHTCILI--------------------------------- ----------------------------------------------------------TP PPDPCEDGRHNCAPASQARCIHHGDG-SFSCACLPGYAGDGHRCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPSATC--SNTPGSFSCRCQPGYYGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------P-------EPTQRP-RTV CERWRESLLEHYGGT-------PRDDQYVPQCDGLGHFTPLQ------------------ -----------------C------HGKSDFCWCVDQ-DGREVQGTRSQPGITPA------ ---CIPTV-APPTIRPTPR-------PDVTP-------PPVG-T---------------- ---FLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHG-SIVVGIDYDCRERMVYWTDVAGR TISRASLEPGAEPETVIN-SGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDG-SERRA LFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECILPDG--TGRRVIQN----NLNYPFNIVS-YADHFYHTDWR RDGV-IAVNRDTS-QFTDE--YLPE-QRSHLYGITAVYPYCP-G--KQLLRQRLGISRVE ----------EDRSSS-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >KAB0344697.1 hypothetical protein FD754_021623 [Muntiacus muntjak] MR--------------------------------GDPAAGRPA----------------- ------LP---------------------------------------------------- ------PP--LLLLLLLSRAAALHP----SELFPY---GQSRGDQLLQEGDDE--SSAAV KLTLSLRFYDAQFSDLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS GG--RGRVLYR-QDTSPAVLGLAASYVRAGFPLS----SVHFTPTHAFLATWEQVGAYEE AKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQ----LPAR VGFCRGEVDDL---NRQGPYFSLT-STEQSVKNLYQHSNLGIPGVWAFHIGST----SPL DNIRPATVGGD-LSKARPSAP---LGQSFSHAVALEGDYTQDPL-D----DYDEIEEE-- -------IEYPPSEPAE-ASNGHSSVDVSLRDR---------ISAPDSDLASPV----PP SASQGGP---ETESSPLDPHTKERRPQGETDASDLKGRVESSEQPGTRVPTPAETEGDLP APPGEAPPPSPEG---------GAGPVDQDALPAHPGGEA-ALPNYP-GPDHAPHLGHR- RQVVGV-EDDISSNTEVFTYNAANKETCE--HNHERCSRH-AFCTDYATGFCCHCQSRFY GNGKHCLPEGAPHRVNGKVSGHLLVGHTPVH---FTDVDLHAYVVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGW-ENGFSLTGATFIHDVEVTFYPGEERARITQT AEGLDPE------NYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYA-DSAVTSTSTRTY SLMS-GAINQTRSYRIHQNITYQV---CRHAPRHWA-VPITQQL--NVDRVFALYSDEEK VLRFAVTN----QIGPVE------------------------------------------ ------------------------------------------DVNECATGFHRCGPNSVC VNLLGSYRCECRSGYEFADDRHTCILI--------------------------------- ----------------------------------------------------------TP PPDPCEDGRHNCAPASQARCIHHGDG-SFSCACLPGYAGDGHRCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPSATC--SNTPGSFSCRCQPGYYGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------P-------EPTQRP-RTV CERWRESLLEHYGGT-------PRDDQYVPQCDGLGHFTPLQ------------------ -----------------C------HGKSDFCWCVDQ-DGREVQGTRSQPGITPA------ ---CIPTV-APPTFRPTPR-------PDVTP-------PPVG-T---------------- ---FLLYAQGQQIGHLPLNGTRLQKDVAKTLLSLHG-SIVVGIDYDCRERMVYWTDVAGR TISRASLEPGAEPETVIN-SGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDG-SERRA LFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECILPDG--TGRRVIQN----NLNYPFNIVS-YADHFYHTDWR RDGV-IAVNRDTG-QFTDE--YLPE-QRSHLYGITAVYPYCP-G--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >KAB0375038.1 hypothetical protein FD755_013530 [Muntiacus reevesi] MR--------------------------------GDPAAGRPA----------------- ------LP---------------------------------------------------- ------PPLLLLLLLLLSRAAALHP----SELFPY---GQSRGDQLLQEGDDE--SSAAV KLTLSLRFYDAQFSDLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS GG--RGRVLYR-QDTSPAVLGLAASYVRAGFPLS----GAHFTPTHAFLATWEQVGAYEE AKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQ----LPAR VGFCRGEVDDL---NRQGPYFSLT-STEQSVKNLYQHSNLGIPGVWAFHIGST----SSL DNVRPATVGGD-LSKARPLAP---LGQSFSHAVALEGDYTQDPL-D----DYDEIEEE-- -------IEYPPSEPAE-ASNGHSSVDVSLRDR---------ISAPDSDLASPV----PP SASRGGP---ETESSRLDPHTKERRPQGETDASDLKGRVESSEQPGTRVPTPPETEGDLP APPGEALPPSPEG---------GAGPADQDALPAHPGGEA-ALPNYP-GPDHAPHLGHR- RQVVGV-EDDISSNTEVFTYNAANKETCE--HNHERCSRH-AFCTDYATGFCCHCQSRFY GNGKHCLPEGAPHRVNGKVSGHLLVGHTPVH---FTDVDLHAYVVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGW-ENGFSLTGATFIHDVEVTFYPGEERARITQT AEGLDPE------NYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYT-DSAVTSTSTRTY SLMS-GAINQTRSYRIHQNITYQV---CRHAPRHWA-VPITQQL--NVDRVFALYSDEEK VLRFAVTN----QIGPVE------------------------------------------ ------------------------------------------------------------ -------------------------VI--------------------------------- ----------------------------------------------------------TP PPDPCEDGRHNCAPASQAQCIHHGDG-SFSCACLPGYAGDGHRCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPSATC--SNTPGSFSCRCQPGYYGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------P-------EPTQRP-RTV CERWRESLLEHYGGT-------PRDDQYVPQCDGLGHFTPLQ------------------ -----------------C------HGKSDFCWCVDQ-DGREVQGTRSQPGITPA------ ---CIPTV-APPTFRPTPR-------PDVTP-------PPVG-T---------------- ---FLLYAQGQQIGHLPLNGTRLQKDVAKTLLSLHG-SIVVGIDYDCRERMVYWTDVAGR TISRASLEPGAEPETVIN-SGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDG-SERRA LFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECILPDG--TGRRVIQN----NLNYPFNIVS-YADHFYHTDWR RDGV-IAVNRDTG-QFTDE--YLPE-QRSHLYGITAVYPYCP-G--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_020724590.1 nidogen-2-like [Odocoileus virginianus texanus] MR--------------------------------GDPAAGRPA----------------- ------LP---------------------------------------------------- ------PPLLLMLLLLLSRAAALHP----SELFPY---GQSRGDQLLQEGDDE--SSAAV KLTLSLRFYDAQFSDLYVGTNGIISTQDFPRE---TQYVDDDFPTDFPAIAPFLADIDTS GG--RGRVLYR-QDTSPEVLGLAASYVRAGFPLS----GAHFTPTHAFLATWEQVGAYEE AKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQ----LPAR VGFCRGEVDDL---NRQGPYFSLT-STEQSVKNLYQHSNLGIPGVWAFHIGST----SPL DNVRPATIGGD-LSKARPSAP---LGQSFSHAVALEDDYTQDPL-D----DYDENEEE-- -------IEYPPSEPAE-ASNGHSSVDVSLRGR---------ISAPDSDLASPV----PR SASRGGP---ETESSPLDPHTKERRPQGETDASDLKGRVESSEQPGTRVPAPPETEGDSP APPGEAPPPSPEG---------GAGPADQDALPAHPGGEA-ALPNYP-GPDHAPHLGHR- RQVVGV-EDDISSNTEVFTYNAANKETCE--HNHERCSRH-AFCTDYAAGFCCHCQSRFY GNGKHCLPEGAPHRVNGKVSGHLLVGHTPVH---FTDVDLHAYVVGNDGRAYTAIS-HIP QPAAQALLPLTPIGGLFGWLFALEKPGW-ENGFSLTGATFIHDVEVTFYPGEERVRITQT AEGLDPE------NYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYA-DSAVTSTSTRTY SLMS-GATNQTRSYRIHQNITYQV---CRHAPRHWA-VPITQQL--NVDRVFALYSDEEK VLRFAVTN----QIGPVE------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------DKV------------- --------------------------------VSMSKI---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_018084587.1 nidogen 2 L homeolog isoform X1 [Xenopus laevis] MH------------------------IP-TAIPAGTAATARSKSLFPSNQCARREEPGVI LRLGLSAPCSSVYWSATATPTLGSALGSDVEAPGSELLSTLGRGAYPLALNVGLASIRIV AMWDRTVRLLLPLHCLLAFSAAISR----RELFPY---GELKGDVLLQEGDDE--TSEVV KLSQPLLFYEAQFSNLYVGTNGIISTQDFPRE---TQYVDDGFPTDFPVIAPFLSDIDTS NG--KGKIFYR-QDNSEPVLNHAAREIQRGFPE------ATFIPNHAFLVTWENVGTYEE VTRHSASSDRRNTFQAVLAYDHSDAYAIFLYPEDGLQFFGTRPKESYNVHIE----LPAR VGFSRSEA---------GPYYSVT-SNEQSVKNLYQTGNVGVPGIWVFHIGSI----WEL DNVIPAKFFGA-PANEQSLEN---SHTSFPEHRLFENHENEDSI-DYPESFYEESEDELE DNTSDATPTHETHQEGDSNTGNQGYLDIDDQASKL-------THAEDEQKATSS---AVL SSSHQNPNW-----TPYTPSESE--------TDRDGPLQEPQIQTGE-----NLDLTRED TLLTDDLPSHNAPDSI---------PSNSEDLPIYPESAV-LVGSHP---EQENNFERG- ---RQT-DADPGLQTDVFSFKPAGKETCE--RNHGRCSRF-AFCADYSTGFCCHCQEDYY GNGVHCLPRGAPHRVNGKVSGNILVGQTPVN---FIDADLHAYIVANDGRAYTAIS-NVP DPASWSLTPLAPIGGLFGWLFALEKPGF-QNGFSFTGAKFVHNIDVTFYPGEEAIHITQT ANGFDSE------GYMNVKTAIQGKIPYIPETSTIKLSPYTELYQYS-GSVVTSTAYREY TVLSESNEEQKLSYRLRQNVTYQE---CSHSQKQ---SVSAQKL--YVDRVFALYNKEEK VLRYAITN----YIGSVHDST--------------------------GEEDLKVNPCYDG THLCD-TRAKCQPGSGLEYICVCASGYQG----DGRD---CTDVNECEVGFTRCGQNTVC VNLQGSYRCECASGFTLSGDEHNCILA--------------------------------- -----------------------------------------------------------S SINPCEDGRHMCN-RDTSRCVPHGDG-VYTCQCFPGFIMSGEKCV--------------- -------------------------------DVD-------ECT---------------- --------------------------EHRCHPDASC--TNTLGSFSCRCNSGYEGDGFQ- CTQILDP----------------------------------------------------- -------------------------------------------------EPLRTPCLEKR QQLL-------------------------------------------------------- --------------------------------------------GQLHPRG--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------PR------------PVVGQFVPECDAEGNYVPLQCHGS---TGHCWCV D-KLGEEVAET--------------------RTPPGRPSPNCGDKGPE-PLRTPCLEKRQ QLLGQLHPRGSRPVVGQFV----------------------------------------- ---------------------------------------PECDAEGNYVPLQCHGSTGHC ----WCVDKLGEEIAGTRTQPGRTSPNCADK----------------------------- ----------------------------------------------------GPEPLRTP CLEKRQQLLGQLH----------------------------------------------- ------------------------------------------------------------ ---------------------------------------------SRGPHPIVGQ----- ---FVPECD-VEGNYVPLQCHGSTG----------HCWCVDK-LGE-------------- ----EVAGTRTPPGRPSPNCGDT------------------------------------- ------------------------------------------A-------EPTQRP-QTV CERWKQSLIEHYGGK-------PSGEHYVPQCDQYGDFSPLQ------------------ -----------------C------HGNSGYCWCVDK-EGREIEGSRTEPGMTPA------ ---CIPTV-APPTMHPTPR-------PDVTP-------PATG-T---------------- ---FLLYAQGQQIGYLPLNGTRLHKDKARTLLSLHG-SIVVGIDYDCHEKMVYWTDVAGR TINRASLEPGAEAEIIIN-TGLMSTEGLAIDYLRRTLFWTDSGLDKIESSRLDG-TERKI LFDTQLVNPRAITVDAVRGNLYWTDWNREAPKIESSFVDGSNRRILVN-DNIGLPNGLTF DPFSKQVCWADAGTKKLECILSDG--TGRRVIQS----NLNYPFSVVA-YANHFYHTDWR RDGV-ISIKKDTG-HIVEE--YLPE-QRSHLYGITAVYPYCPSG--RK------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >OWK09497.1 NID2 [Cervus elaphus hippelaphus] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------GAT------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------RVP P----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------QL---------------- ---VAIRR----QVWPTPASV--------------------------------------- ----------------------------------------HLDVDECATGFHRCGPNSVC VNLLGSYRCECRSGYEFADDRHTCILI--------------------------------- ----------------------------------------------------------TP PPDPCEDGRHNCAPASQARCIHHGDG-SFSCACLPGYAGDGHRCT--------------- -------------------------------DVD-------ECS---------------- --------------------------ENRCHPSATC--SNTPGSFSCRCQPGYYGDGFQ- CT---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------P-------EPTQRP-RTV CERWRESLLEHYGGT-------PRDDQYVPQCEGLGHFTPLQ------------------ -----------------C------HGKSDFCWCVDQ-DGREVQGTRSQPGITPA------ ---CIPTV-APPTIRPTPR-------PDVTP-------PPVG-T---------------- ---FLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHG-SIVVGIDYDCRERMVYWTDVAGR TISRASLEPGAEPETVIN-SGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDG-SERRA LFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVN-KDIGLPNGLTF DPFSKLLCWADAGTKKLECILPDG--TGRRVIQN----NLNYPFNIVS-YADHFYHTDWR RDGV-IAVNRDTS-QFTDE--YLPE-QRSHLYGITAVYPYCP-G--KQLLRQRLGISRVE ----------EHRSSS-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_791550.3 nidogen-1 [Strongylocentrotus purpuratus] MK---------------------------------------------------------- ------------------------------------------------------------ -------LLLGIFAVLIAVVNCLPR----DQFFPF---GEGTTDKKLNRRSKK---PLTL SFREPFTFLGEEQSLLYIVRDGYVSFSSGARG---------------SKIAPFHTKLKLI RG--QSSVWYR-TTVSSNEEDEIINLIQRNFRSRGSTDFTTFSPSSFVIVTWENMAVRNS ----DHEVIGTVTFQLILVADAMHSFAFFLYDENN--------DYPRPDRIG----SNID AGFTSGKAHNQ---WEFEMVYTTEDNKAATLFEAMRDSNVGMNGMWAYKIDGR-----MD GNIIPA------------------------------------------------------ -------VAYVPVESLP------------------------------------------- -------QNDE---PPQD------------------------------------------ ------------------------------------------------------------ --AVNI-QLDNTFDVVL-----DFENQCT----RETCSVD-GRCVPYPTGHCCACNEGFM GNGIHCLSINDNGRMNGRVNGTINGVTIP------DEVYLHTFIMGGGGRTFTAIS-PVP SSIAYSMQILLPIGELMGWMFAEPAAKG-INGFMQTGGDLLYSANIRFENGDE-VSIIQR YTGVDESEEG--GGVIGGYVTIDGNVPNLSPGTSVSVDRHSEVYTKYRPGYVYSSEQRSL -----DADGQTIRFSIEQTITYQE---CEADDINTDASLTAMRM--NTTYAYSIFEPQGD ILRYAMIT----NVGPDIGVP--------------------------------TDACQDN N--CG-TNAECFPQAN-TFTCRCRAGYTG----NGYT---CTESPSDPCDNNDCDRNANC YPAGNSYTCQCNTGFN--GDGRVCVAD--------------------------------- -----------------------------------------------------------Q ASDPCDTND--CS--LYAYCYPTNDGQSFYCQCATGFTGDGRNCE--------------- ----------------------------REQRGN-------ACD---------------- --------------------------NNNCSPYAYCR-PRGDTDFTCECAPGYVGDGYN- CEEESQD----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------PCLNNRCHPY-----ADC------------- -------------------------------SPVPGGYTCSCR-SGYQ-GDGYLCEEADQ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---LVNLCS--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------DCGRDADCLP-------------------- ------------------------EGRGYRCICRAGFNGDGLTCEDVDECLEGADIACDA NARCQNNR-GSYTCRCNAGYRGDGFTCEALP-------EADG------------------ ---SLVFGQGMSVMNLPRDGSA-----GNKVYMKSR-QTVVGLGYDCRHEYVYWTDISGR AIMKASLD-GRDVSVVVN-TSLSSPEGVAVDHLSRNLYWTDSGFDRIEVANLDG-TNRHV LFDTDLVNPRAIVIDPVGGYLYWVDWDRSYPRIEVSGMDGSGRAVFLD-EDLIMPNGLTI DLVSQLLCWADAGTQKVECMNLDGDPLSRYPVYR----PAQYPFGLAS-LGNNLYWTDWQ TSNI-QFINKNGG-EVQSL--ALPRGGNGRTYGIAAVTQ-CTDG--NNRCAYENGGCRN- -LCLPAPG--VRATCVCPNAL----APNDIPCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_038046990.1 fibropellin-1-like isoform X23 [Patiria miniata] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------AWLFALPSGKG-YNGFMLTGGKFRQTLNITFSTGEQ-MLITQD FQGVDEN------GYIRVIADWNGNIPEITPSDYVFVDDHKEEYVRHRLGVIHTFAKRSL QV-----NDDTISYTMDQTIEYDE---CSADEADTEYILNFMRV--SMTETYLIYEASEE ILRFSMIG----KVTPASEQI--------------------------------DDPCVSN N--CD-RNAQCLPAGDSGFRCKCNEGYEG----NGQT---CTGSNPCA--QNSCDVNGYC IPQADRYTCACNAGYQ--GDGYTCSVD--------------------------------- --------RCASSRCDPNARCVETTQ--------GYECYCNAGFTG-------DG-FRCQ VSNPCDNNA--CD--ANAYCVPTQSG--YQCYCNDGYSGDGYNCQ--------------- -----------------------------EEESD-------HCA---------------- --------------------------NNNCDPNARC--VSAVFGYQCFCDPGYRGDGYT- CQANNAT--------------DPCAN---------------------------HTCDTNA R-----CVASAQDTYECYCFEGY---TGDGFTCEVDPANPCASNTCDANARCVASAQDAY ECSCLEGYTG----------------------------------DGFT------------ ---------------CE------------VNPANPCAINTCDANARCVASA--QDAYECS CLE--GYTGDGFTCEVNPTNP-CAIN---------------------------------T CDANARC--VASAQDAYECSCLEGYTGDGFTCEVNPANPCAINTCD-------VNARCVA TAQDAYECSCLEGYTGDGFTCEVAVDPANPCAINTCDAN-----ARCVASAQDAYECSCL E---GYTGDGFTCNATDPCASNVCDPNARCVAFSPAIYECSCL-EGYT-GDGLTCEANTT D--PCVNNA--CDMNARCV----------------------------------------- -----------------------------------------ASAQDAY---ECSCLEGYS GDGFTCMANTTDPCVNNACDTNARCVASAQD----------------------------- --------------------AYECYC--FEGYTGDGFT---------CEAEQINFCANNN CDRNARCVPTQTG----------------------------------------------- ------------------------------------------------------------ --------------------------------------------YQCFCNQGYEGDGYSC RATQIDRCA-NNACDVNAYCVSTASA--------YNCYCNDGFSGD-------------- ----GFVCREIVDPCANNNCDV-------------------------------------- -------------------------------------------NARC---VPSQSGYQCY CN-------QGFNGDGFTCQAVSVDLCYNNRCDFNAECSPAQDGGYSCTCNQGYEGDGFT CRNTLVNLCSACDASAQCI----PEGRGFRCVCRSGFQGNGLVCEDIDECSQSGAA-CHR YATCYNVR-GSFSCYCQPGYEGDGFSCQEVTQ------PELDDG---------------- ---ALIYARGMAVMRVPLNANK----PGNKIVFRSG-QTIVGLGYDCQEEYIYWTDVSGR TISRAKAD-GSSTEVLIS-RGLSSPEGVAVDWLSRNMYWTDSGYDRIEVANLDG-SNRRV LLKTDMINPRAIAVDPIGGLMYWTDWNRDAPKIERANMDGSERSVLVD-SNLGLPNGLSL DYTTSQICWTDAGTKRIECMNMNGDPLTRFTVLP----NSNYPFSIAS-YGFKLYWSDWE TKSI-QTISKTGGSESTDL--KLPRGGNGRIYSVTAITS-CPST--SNACSSNNGGCSS- -LCLPTQG--GQRYCACPTNL----EGNEVPCV--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_026296012.1 LOW QUALITY PROTEIN: nidogen-2 [Apis mellifera] MVENNQSRESSPILACEEASVGAMEGGPRHEIIGGTGRESRETTVFHAFERRAAERTSGQ RRLGGGKRELVVAFVAV---SIDSSVKAVRER--------MTRRACRLSVS--------- -----WPALVLATLVIAPFAVALNK----NDLYPY----SIPGTSILQTDPNGLLLSAET ILKTPIAFYDQIFNSIFVNGNGVLSFARAM-----HRFFNIAFPLDDPVIAPLYTHVDTR GS---GRVYYG-ETDAPEILARAGGMVRSAFTDA-----ADFVPTHAFLATWVDVGYYNG ------KSDKVNTYQVAISSNGTHSYVELLYPDDGIQWI-----QGESHPNGL-PDAKAQ AGLMS-----------EGRMYTLRGSGTDQIQNVDKWSNVNRPGQWVFQVGPI----SDE EDIK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPDNVEDSSA----TNEVANCR--TGATACHSK-ATCVDYEVGFCCHCKQGFF GNGKSCQPNDVPLRVNGRISGTINGVE-------FLARDLQCYVQTKDGRTYTALS-RVP EEIGASFQLLGNLGGVIGWLFAKPIGET-KNGYELTGGLFNHTAELTFPSTGDKVTIRSN YLGLDVF------GQLKMQAQIEGTLPQLGRDTGLDYGDYDELYTRVQTGVIRSRAERVC KLAE-GVESRELDFVQDETIYYNE---CPYLTVEP--EDDTTRL--KFFRGVTTYEATEG IIRFAVNT----KVAPLEE----------------------------------EDPCIQG RETCG-DHSYCVVDGD-SFKCVCNPGYQYLYEEDGSA--ICIDVNECTAGKHMCSPDAQC INQEGSHTCQCRPGFS--GDGRTCDKLP-------------------------------- --------SCEDTRCDNYEQCVMIEG--------APNCICLPGFED-----TEQGCYPAT QRAPCDVED-NCS--PNGFCNIDAEKQKYVCVCLPGFIGDGYTCYPDAEVTTTDEPPKPQ CIEEMCWCSSGWEYRNNECVRQEEETRTADYDRDLSARPLPECYEDNCICPWGHNYDRSK EICVPRPGYKHETMGPSGVHL-SCNVMNRCHPYAQCIYVTSTADYECRCNQGYEGDGME- CIKTEVS----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------CLEVDICDPN-----ASCQQ----------- -------------------------------EESLA--KCVCN-PGFE-GDGTMCSPIDE ----CSSSS--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------Y CLENERCLYNSAS----------------------------------------------- ------------------------------------------------------------ ------------------------------------------SRYECTCNPGYSM----- ---VDSRCVVSDCSTNPSQCHVNAQCT-SIGEGGYRCVCAEGYNGD-------------- ----GIRQCVED------------------------------------------------ ---------------------------------------------------------HIG CN-------------------------VLNNCGRNAVCGYNQ------------------ ------------------------TSANFVCVCQQGYYGDGFTCLPQSSCRHDPAI-CSP DATCVAAGENQYACVCNEGFIGDGTNCKSRP-------KHEA-N---------------- ---FLLVNQGMATLRIPFAPTY--EDPGSPIYIAYM-QMAIAIDIDCMNGKAYSSDISGN RIIELTYN-GSMAETFLP--KVSNPEGLAIDWVSRNIFWT--GKTTVEVANLET-KKRKV LVSDGLVNPRGIAVHPYRGKIFWSDWNRASPKLEWANEDGTDRAIFLQGDYVKLPNSLSI DWAMDELCWADAGTFTISCMEIDS--RKINVVAN----QLTYPFGLAI-SQQHYYWTDWK THKI-EVAMKSTGDRKQAI--SVPPGGSGKLYGIVVVPESCPRV--TNACQFEGGRCSKN QLCLPNGQ--NGRSCVCADDA----DG---PCT------------------------DNL ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_039259166.1 nidogen-like [Styela clava] MK---------------------------------------------------------- ------------------------------------------------------------ ------TVAVLLAVFAVGQSAVF------NDFYPF----DRENDHRVPKGDNT--SSPQF ELDLPIIFYDSVYNGIKVNADGFVTLGVVEHE--IEEHLLE------PVLVPFGFNLNNT DA---SEIYYQ-EHKDEATLSRATNDIQKAFVET----AEAFVAKSAFIVTWVRLESPEH -------PGLTFTFQCVVVSNHLSSFAIFLYADDELA-----AGQSEEIRNQ----LIAK AGFSDKGGDQL---------------ESMTATELLEGGNAWSTGEWIFQIGGVLLSLEEE EEIP-------------------------------------------------------- -------SHHLKAEPIH------------------------------------------- -------HRRE---SGFE------------------------------------------ ------------------------------------------------------------ -------VPEVNFNEDY----GSDQQDCD----SLECDPEFSTCTAFADGYCCQCSEGSF GNGYACIREDDDVRYNGQVDGYSIVMSDPWSNETAKGVDMHSYVVTKDGRAFSVMNGEIS AKLYRALQPMAIFGTTLGWLFAQAEAPA-INGFQYSGGKIVSETYIRYTTGQYEFRIRQE YDQVINDPEGGEGKVLNGRMTFSGRLPPVEEGENINVDDYTQIYKRTGADSIRSRDTRRY IV-----GDTEHIFTVDQSIRFEG---CEASFEE---VPADLAV--DVSEVFLKFFPDEN NLRFAVNS----RIRPAEEVG-----------------VRPVE-----PSIIPDTPVPDT P---------------------------------------VPDTPE-------------- ------------------------------------------------------------ ---------------------------------------------------------PTP SETPVEKPE--------------------------------------------------- -----------------------------EPEIP-------EVV----VTP--------- ------------------------ATQTVCERQ-----LQQVQQFQ-RENPGIVDEIFF- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------PTCTDVGTFAPRQCLTY---NSICWCV DEDTGEEIHGTR-------------------TEPLVGYQLDCSDVRAPPPAQTPCQEDRS ----NAETD--RIVAG-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------SEANSI----- ---FMPRCM-ESGAYEPVQQLPDGS-----------FMCVDF-DGE-------------- ----EISRSTEMP-----NC---------------------------------------- -------------------------------------------------LTPCQLA-AYV AESSNIFL---------------ETNEFVVRCKADGDYNPEQ------------------ -----------------C--------VETYCYCVDE-NGLEITNSRVETTFGED-----V DLDCGKFN-SKPVTSTVTT-------PTTTT------GPIVGQEV--------------- --RRLLFAQTMGINVIDLPVTR-ENSVSRRLFARSD-QITIALGYDCSSKKYYWTDVSKR RIYSSVLDGDGSRAQFLG-DRLRSPEGISVDFLSGNVYWTDSEYDRIEVASADG-SNRMT VVSGDIVNPRGIAVDPIRGRMYWTDWNRKAPKVWVANMDGSDRRVLLS-EGLGLPNDITI DFYRQRVCFVDAGTFKVECMSLNG--EGRETIYQMKQVPRPHPFGLAV-DGDVLYYSSWG GSKVVHAVNWRTG-DSIAI--AGPRGAHGQMYGVEIAHSQCPRG--YNYCSSNNGGCSH- -LCLPTP---TGRECVCPPGA----QD----CQ--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >NP_001256467.1 NIDogen (basement membrane protein) [Caenorhabditis elegans] MK---------------------------------------------------------- ------------------------------------------------------------ -----HKKMLILLFLYLLIETTTAN----PAFYPY---GQPAGDNRLDYSMEQ----SAI ALKIPLTYMEQSVDELFLSHNGIVGLGKPT-----PEKIGGLMTISTPAIAVFYVPVTS- -----GVIDYRVSSDDQGLLTKLTQDVKQVFADA-----VEFHGLQAVIITWTQIENAEK --------DGPASFQLAIVSDGISTYAIFRYES-----------LPWSSSMG----YYAQ AGFVRSI----------GKIQTNVNSGGPDVKELVNLSNNQFGNFFIFRVSGS----AIE DPKDEGAD------------------------------------------DYDYNNYD-- -------QEYEGEHPAD------CPKDKFVDNCPA-------ECRTVRDER-----GCER CICAERPHAPR---APQEPRPELENTVED-----------------------DE-DDEQV DGTRYEEP---------------ARQAQEQHHQQHHQ----------------------- -------PDQPQQQPQRSQEGSLPKMSCSQ-RDDKSCHAN-SVCQDFEGGFCCNCDTGFY GNGKECLPKGEPQRISGSFEGVIN--RIPI-----DKTELHTFATSTDGNVHTAVS-KIP SDLGHPLRFLYSIGGVMGWLFADVQSPNVYNGFQLTGGLFNRTVALHIEQNYY-VTIKQE FSGRNIH------DYFKSHLFVSGTLPDIAPGSEVIFPDYEEEYVRERRGYLTSKAAFDV IVRD-GGNVQTYRMSVDQQITFEE---CPNKEFD---RDHSMKL--HVKRINVVYNDDEG VVRYGAKNFATRSVGPAVSAPSGGHFDRRQHGQSNMASERPIEIPSQSESISTDSVCAPG RHQCTLPNMKCRVVDP-SYRCECEPGYQAAHDASSHIGWICQDLDECQRGDHNCDQHAKC TNRPGSFSCQCLQGYQ--GDGRSCIRE--------------------------------- ------------HQASHHEH---------------------------------------N QQTPQEM--------------------AGVGATTEGF----------------------- ------------------------------------------CT---------------- -------------------------AHNQCHQWGECVFTSEHPTGRCKCRGWYVGDGVNH CGPPEEN--------------MPKHN---------------------------------- ---------------------------------------------ANIPQR--------- ---------G-------------------------------------------------- ------------------------------------------------------------ -----GQ----------------------------------------------------- ------------------------------------------------------------ -----------------------------ACGSYVCDVN-----AECM------------ -------------------------------PEPSGGSECVCK-AGFS-GNGVTCESLLD D--RHAHSSHN------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---RHEQQQ-QTGS-----------------------------LGK-------------- ------------------------------------------------------------ -----------------------------------------------------------V CR-------------------------SHDECSEHGSCAYHH------------------ ------------------------SLGYYQCACTEPYVGNGVE----------------- ---CTLPG-SSASAESSTR-------------S----------D---------------- ---KLLVARGMAIFERSTNPDE----YGKQLIVIPH-HIPVGIDFDCKEEKIVWSDMSGH SIRTSSLN-GTEHKSYFN-KELSSPEGIAVDWSSRNVYYADSMNDEIGVASLNG-KFKKS LVTEGLVNPRSVVLDLYGRHLYYSDWHRENPYIGRVDMDGKNNRVFLN-EDVHLPNGLTI LPNRRELCWVDAGNHRLSCIQYNG--AGRRTVFS----SLQYPFGLTHDEEQKFYWTDWK DNRI-HSVGVYGE-GYRSF--QISLGGSGKVFGILAVPKSCVGP--STPCSEDNGGCQH- -LCLPGQ---NGAVCECPDNV--KVKG----C---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >NP_610575.1 Nidogen/entactin, isoform A [Drosophila melanogaster] MP---------------------------------------------------------- --------------------TFGSKLL-----------------ACLL------------ -----LSSVILVSGQFEHYLDSLRA----SELYEFE-DGSLGSIHLLPKGDSE---TIVL QLEQPIHFYGEQYEQLYINTNGILTFNSEF-----PEYLNQPFPLEYASIAAFYSNVDTS FSDEGTSISLF-ESKEQSILDRASSLVRYAFSSQ-----SEFEARQVIVATWRNVGYFDS ------KTDRLNTFQVALIANEQSTFVQFIYPDGGLNWL-----QGETAGLGL-PDIRAQ AGFVAED----------GRFYTLNGSGSENARFLSESTNLGVPGVWLFEVAPI----ENE QNVR-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------SPD---NAESLTESPALALSCQ--AHAHQCHEK-AECHDKAEGYCCVCGSGFY GNGKSCLANDQPIRVTGTLTGELN--KQPVS----EEAKLQSYVVTSEGRTYTTIN-PLT PELGAQLRLVLPLLTTVPWLFAKSVGGV-ANGYQLTGGVYTHVSRLQFDSGEN-LHVNQT FEGLNYW------DQLSVKIEIYGEVPAVAADAVLILPDYVEEYTFERPGELKSVQVLNI NITE---EQRVLGLQVEQRILYRS---CLRDDEA---DPSATKVLQKISKVALDYVERDQ ALRIGAMS----KVGVTPE----------------------------------SNACNDG TADCV-ENSVCVPYED-TYRCDCYHGFAAQLDERGVE--VCLDIDECATGSHVCDENAVC DNTEGGFNCYCTEGFE--GNGYRCLSN--------------------------------- ------------STADNIEYPPAVEGQAEPTSEPSPNPSPYPDQGQDQEREREDDQYPQP NPYPYPEEQIPQHPDECYRCSKDADCYQGRCTCHEGFDGDGYTCTN-------------- ------ICGHGEVWENGRC----EPLLLERHDVDPLCDALGECR-----CPYGYELSEDS QRCT----YVQEFDGERNADLIPCDVDENCHINATCNWYGQELRHICTCQPGFRGDGYN- CDPISDD----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------SC------------------------------------- ------------------------------------------------------------ -----------------------------AIRPDICDVH-----ADCVY----------- -------------------------------EEHLGKSECQCQ-AGYT-GNGFNCQLAAE ----CQSAE--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------H CGENAFC----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------DDGVCRCQADFERD---- ---VSDRCV-PAGRCGSVFCGSNAICKWDSAEGVQYCDCLDGYQGD-------------- ----ALTGCTSKP----------------------------------------------- ----------------------------------------------------------LS CH-------------------------VLNNCGIHATCEPTE------------------ ------------------------DPANYECQCIAGFKGDGYVCIEEQNCLNNPTL-CDM NAQCRSTN-SGLVCVCNQGFFGNGSLCQERQ-------HQDS-D---------------- ---FLIVSQGVMIARVPLNGRNVRP-------ISVA-QMAIGLDKDCVEGRVYWGDISTK KIVSTKYD-GTDLRPFIT-TDIESPEGIAIDVISRRLYWADSAKDTIEVASLDDPSLRAV IINKQLVNPRGIAVDPYREKLFWSDWDRESPKIEMSNLDGTGRELLLGKDDVTLPNSLVV LENSGEVCYADAGTKKVECIEPQN--RQIRTISN----ELSYPFGITF-THDQFYWTDWT TKKV-EIVDSLGA-RQTPI--QPPFFGSHKMYGMTVVEQHCPQY--QSPCQISNGGCTDS RLCLVNRQAPSGKSCKCTSAS----TG----CT--------------------------- ------------------------------------------------------------ --------------------------------------VLAP--GY-------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ >XP_031557799.1 nidogen-like [Actinia tenebrosa] MA---------------------------------------------------------- ------------------------------------------------------------ -----SRNLVFLLVLLVIQSSCLVLGARIQEFYPDGIDGPRGSSELLARR-----ISPPV TLGTTYNLYGKPYTSLRVYKNGLITLGEEPISFSPQKHRKFLFPPEAKVIAPFYGQGDFT NT---SRISYG-ETRDSDILTRASKDVKQSFSGE-----DEFNASAVFIVTWCQVKHAQH -----SQHKKNNTFQAVLVTNGDQTFVIFNYLTRGLQWA-----KGYHSQWKGAKYAYAQ VGFSAGD---------FVRYSTLPGSGTNQVHWLASKSNMNTPGRWIYKVGWP----GMH GNEVQSADSFE-------------IDDSTNT------DFFAAQF-------YDGCFVV-- -------HGYLTANRSQ------IWKDVSIRSCIA-------LCFERRQKYAALHNGSQC ACLNDIRHLIK---TNTDQDCDMACSVND-----------------------DEVCGGQM TASVYQ------------------------------------------------------ ----SVGLAAVQSDQSGGQRKRKDVDECA--VGVVSCHAN-ATCINKSPGYCCQCNEGFY GNGITCIEIGAVQRMVGFLSGTVNGEE-------FISLNMDTIAFSDDGRAYVSVR-AFP PYLAHSARVLTPLTDVVGWMYAKPKPSGFYNGYNVVGARFVRRASLRFDSGEE-LAILQK YQGRDVL-----SHYMKVETTMNGAIPRIHPKAEVRMRKFRQEFQRTAAGRVQSRGTVKY QV-----DGREHYFTVDQFIDYDEQKRCGQHVVRG--VLEADVL-------TSNYDPAQA FLGIAVKG--T-FINTTLDSI-------------------------DVQSQEADKMCGSK KVTCH-TRGVCIQYRG-DKECRCNHGYLG----DGVT--YCDDADECKLGRYRCAPDADC VNTVGSYRCVCKKGYV--GDGKTCQKDSVIQCPRPCGANAKCVKIALGLLCNCNPDYQGD GFDCKPDGTCAGIKCDPNAKCATSSDK-------SRKCVCNDGYQG-------DGQTCTA LEGRCGGVV--CS--TNAQCV------QSKCVCNPGFQGNGKNCS--------------- -------------------------------DEN-------ECE---------------- ------------------------LKTHRCDTNADC--INTVGSYSCRCRLGYQGDGLS- CQKASASCGGEKCHRFAYCDVDPQTKKQQCKCRRGFRGNGAECLDFNECIPILKTCDVNA L-----CRNT-LGSYECICKRGFIQGSDDDKTCIVD--DRCNGIKCDVNAR----CDRVQ GCTCKTGFVG----------------------------------DGKT------------ ---------------CN------------DIDECKSEMTRCDPNADCRNTA---GSFTCS CRS--GFEGDGVRCRVDN---SCDGV---------------------------------V CNVNARCE-VQPDGRTRRCVCSNGWQGNGTLCTDVDECQSSRFSCP-------PNTDCI- NSNGSYECRCKRGFEKKGSSCV----EDDSCGGVTCDAK-----ARCVQTPQGTRQCVC- --NTGWQKNGNRCIDKDECQTNPCHPNADC-INSIGSFSCRCK-PGYN-GNGQACNDVDE ----CQSGQSRCPANTDCI----------------------------------------- ------------------------------------------NREGSY---ECRCTTGFV SNGSSCIVD--ESCGGVKCDPNAKCIQIAQG----------------------------- --------------------VRQCVC--NAGWEKNGNT---------CIDVDECRASISP CHSNANCINSIGS----------------------------------------------- ------------------------------------------------------------ --------------------------------------------FSCRCRPGFKG----- ---DGQFCE-DDGTCGGVQCHPDASCHKNTAEG-TRCVCKPGYLGDGRKCADIDECIQGK DECHEHATCTNSAGSYKCSCNLGY-------------------VGDGF--------NCTD DG-----SCQG--------------------------IDCD-PNAKCVASSPTDGNRTCV CN-------DGFSGNGELCRDVDECDLGHAKCHRKAECVNQV-GSYRCRCIRGYVGDGKQ CESDGTCEGKVCDFNADCVTTNTTRGIDKTCKCKDGFSGDGVICTDVDECIKDP---CPP MSQCVNAF-GTYVCQCKPGYKKSNGLCEKICTRCRNGGSCIGENECKCPKGYSGNVCQWY GEASLIYTKGNSVQRMSLPPRS---NAIGLVYNHEG-MVNVGLDYDCVEEYIYWTEVMEG CIMRAKYD-GTNRELVFQRSEVRSPEGLSVDWIGRNLYWTDSGLDVIEVSRLNG-SNRKV LISNGLYDPRAILVDPPSGKMYWSDWTRRRPRIETADMDGTNRRVLVY-DDLGLPNGLTL VQTTNELCYTDAGSWSIRCVDLAG--LNVRKVLT----RVTYPFGIAY-FNRTLYWTDWN QNLI-HRIGVESSTPDSSL--ATFVGKTGKIFDVKAVQP-CPAKVPRNPCSDKNGGCLG- -LCLLKPH--GGYTCSCPKGQFPVKDGNQTTCR--------------------GKCDDPL -----------------------------------------------GME--KGLISD-- ----------------AQLTASSA---------------------------WSNNPKRH- ----GAHRA---------RLNLDTW---PAGWSTKKFDPKPWVQIDLGT----HTMVTGV ATQGLGKSIGEWVKTYRVAYSDDGVTWYV--LRNGGRKKIFVAN---SDSTTVKRNKFPA ALKTRWLRILPRTWHNHVSMRLELYGC---
BMGE Cleaned alignment of selected proteins >sp|Q14112|NID2_HUMAN Nidogen-2 OS=Homo sapiens OX=9606 GN=NID2 PE=1 SV=3 GDRVAGRPVVLLLLPLLMLRAAALHDELFPHWGDQLLQEGDDESSAVVKLANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRGRVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGPYFSLTSTEQSVKNLYLSNLGIPGVWAFHIGSPLDNVRPAAV-GDLSAAHSSVPLGRSFSHATALESDYNEDNLYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQ----------ESSTLDPHTKEGTSLGEGPDLKGQVEPWDERETPAPPEVDRDSLATPPPYPENGPVPSEMDVPPAHPEEEIVLRSYPTPLSRGTYEVGLEDNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHLHVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGSENGFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVSANFTAHISPYKELYHYSDSTVTSTSSRDYSLTFGAINQTWSYRIHQNITYQCRHAPTTQQLNVDRVFALYNEERVLRFAVTNQIGPVKDPTPGNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTENRCHPAATCYNTPGSFSCRCQPGYYGDGFQSLTPCEHIPQCDQGNFLPLQCHGSTGFCWCVDPEVPGTQTPPGSTPPHCGPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDVTPFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQRSHLYGITAVYPYCPTG >tr|X1WE42|X1WE42_DANRE Nidogen 2a (osteonidogen) OS=Danio rerio OX=7955 GN=nid2a PE=1 SV=1 TS-------LFLQLSWAFHHVAGIDHDIYPYYGDVTLQEGDDETSKVITLSKPMHFYEAPFTNLYVTTNGIISTQDLPMEKQYVDDGFPTDFPVIAPFLADIDTSKGKGSIYYRQTESPTVLKRAEADVKRGFPD-ATFSPTHAFIATWENVSAYEEVARSSSPSHRVNTFQVVLAYNEKDTYALFLYPEDGLQFFGTRPKESYNVEIELPARVGFSRGEISYLRTEGPYYSLTSNEQSVKNLYKGNIGEPGVWLFHVGNSFQNVVPAQQEAVSSKSPTVQDTDE----------DYTDE----------EEYDPIDPDF-------------PTTTEFLEPE--TPLGQSP------------------------------LQPSVSLPQPDPHH-EDNTQPQWPLPKHA---ILQVYPVPTHPSGQVFSVEEKVDFDSGVIHYSTDNKETCERFQQQCSLNAHCTDHSTGFCCHCNSGFYGNGRHCLPNGAPQRVNGKVRGTVLVGGTAVDLGNIDLHAYIVVGDGRAYTAISEVPEPAGWALMPVAPIGGLFGWLFALELPNSLNGFSITGAEFTRRADVTFSPGNQRLSIVQTATGLDNQNYLNVDTHLQGSVPFIPPGATVQMEPFKDTYQYYPSLITSTSVREFKVVSENGAETFTFQVKQNITYRCSHRPETLELKMERVFVMYVEERILRYAITNKIGPLGEPENVNPCYSGNHDCDTTARCVPGEGQLFSCQCATGYRGCYDVDECAEGLSSCGAHSHCVNLPGSHRCQCESGFQFGFDGRTCQ------------------------------------------------EQPCHAQALCSNSPGSFRCQCQPGYHGDGFQPKTHCEFIPQCDEGQYRPQQCHGSTGHCWCVDNERAGTRTPPGSPRVNCDQPPTQRPESVCERWRASLLQQYGGQPDSQHYLPQCDSAGEFNPVQYGGSSYCWCVDANGREVPGTRSHDAVKPACIPTVASPTVHPLPRPDVTPSLLYAQGQQIGVLPLNGTQMDKERSSVLLALHGSIVVGIDYDCRERKVYWTDLAGRTINRASLDPGSEPEIIINTALTSPEGLAVDVARRRLFWVDSTLDKIETANLDGSDRHVLFATDLVNPRAMIVDSSTGTLYWTDWNREAPKIESSSVDGQNRRVLVQEGIGLPNALTYDSTMRQVCWADAGTKRLECISPNGTGRRVIQSNLNYPFSMVYFANHYYYTDWRRDGVISLGRDN-QRSHLYGITVAPPQCL-- >NP_032721.2 nidogen-2 precursor [Mus musculus] RDPTAGWLTSLLVMLLLLSRVGALRDELFPYWGDQLLPEGDDESSAAVKLAIPLRFYDAQFSSLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSHSRGRILYREDTSGAVLSLAARYVRTGFPLSSSFTPTHAFLATWEHVGAYEEVSRGAAPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEADDLKREALYFSLTNTEQSVKNLYLSNLGIPGVWAFHIGSALDNVRPATVGGDPSTARSSA-LEHPFSHAAALES-YTEDSFYYDENEEDVEYPPVEPGEAPEGHSRIDVSFNSPGSDRASPWESASLDPQTKQGRPVGEVLDFRDPAELLDQMGTPAPPEADAALLTDL----GGGPVPSEPDV-PVPPLEGEVLPHYPPPLRGGKYVIGLEDHVGSNDQVFTYNGANLETCEHSHGRCSQHAFCTDYTTGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGRLRVGHIPVHFTDVDLHAYIVGNDGRAYTAISHVPQPAAQALLPVLPIGGLFGWLFALEKPGSENGFSLTGATFVHDVEVTFHPGEERVRITQTAEGLDPENYLSIKTNIEGQVPFIPANFTAHITPYKEFYHYRDSVVTSSSSRSFSLTSGSINQTWSYHIDQNITYQCRHAPATQQLTVDRAFALYSDEGVLRFAVTNQIGPVEAPVGVNPCYDGSHTCDTTARCHPGTGVDYTCECTPGFQGCVDVNECATGFHRCGPNSVCVNLVGSYRCECRSGYEFADDQHTCILIAPPPNPCLDGSHTCAPEGQARCIHHGGSSFSCACLPGFIGTGHQCSENRCHEAAICYNTPGSFSCRCQPGYRGDGFHGLKPCEHIPQCDQGNFVPLQCHGSTGFCWCVDREVPGTQTPPGSTPPHCGPEPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHFIPLQHGKSDFCWCVDKDGRELQGTRSQPGTRPACIPTVAPPVVRPTPRPDVTPFLLYAQGQQIGHLPLNGSRLQKDAARTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEAGAEPETIITSGLISPEGLAIDHFRRTMYWTDSGLDKIERAELDGSERKVLFHTDLVNPRAITVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINKDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNHLNYPFSIVSYADHFYHTDWRRDGVISVNKDSGQRSHLYGITAVYPYCPTG >NP_001012005.2 nidogen-2 precursor [Rattus norvegicus] WDPTAGRLASLLLVLVLLSRVGALREELFPYWGDRLLPEGDDESSAAVKLAVPLRFYDAQFSNLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSHSRGRILYREDTSQAVLSLAARYVRTGFPLTSSFTPTHAFLATWEHVGAYEEVRRGAAPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEADDLKREALYFSLTNTEQSVKNLYLSNLGIPGAWAFHIGSALDNVRPATVGGDHSTARSSA-LEHSFNHAAALES-YTEDSFYYNENEEDVEYPPIEPGEALEGHSRIDVSFNSPDSDHASPLESASLDPQTKQGPPVGEVLDFKDPAELLDQTGTPAPPGADAAFLTDL----GNRPVPSEPDV-PVAPLEREILPNYPPPLSGGRYVVGLEDHVSSKDQVFTYNGANRETCEHSHGQCSRHAFCTDYTTGFCCHCQSRFYGNGRHCVPEGAPHRVNGKVSGHLQVGHMPVHFTDVDLHAYIVSNDGRAYTAISQIPQPAAQALLPVLPIGGLFGWLFALEKPGSENGFSLTGATFVHDVEVTFHPGEERVRITQTAEGLDPENYLSLNTNIEGQVPFIPANFTAHIAPYQEFYHHRDSVVTSSSSRSFSLISGSINQTRSYRIDQNITYKCSHAPATQQLTVDRAFALYSEEGVLRFAVTNQIGPVEAPTAVNPCYDGSHTCDTTARCHPGTGVDYTCECTPGFQGCVDVNECATGFHRCGPNSVCVNLVGSYRCECRSGYEFADDRHTCVLIAPPPNPCLDGSHTCAPEGQARCIHHGGSSFSCACLPGFVGTGHQCSENRCHGAAICYNTPGSFSCRCQPGYHGDGFHGLKPCEHIPQCDQGNFVPLQCHGSTGFCWCVDQEVPGTQTPPGSTPPHCGPEPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHFIPLQHGKSDFCWCVDKDGRELPGTRSQPGTMPACIPTVAPPVVRPTPRPDVTPFLLYAQGQQIGHLPLNGSRLQKDAARTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEAGAEPETIITSGLISPEGLAIDHFRRTMYWTDSGLDKIERAGLDGSERKVLFHTDLVNPRAITVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINKDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNHLNYPFSVVSYADHFYHTDWRRDGVISVSKDSGQRSHLYGITAVYPYCPTG >CAE1293091.1 LRP5_6 [Sepia pharaonis] -----------------------------PP-----------------------------------------------------------------------------GYIKYHSQHS------CVGSIERGF---LCFGSPLLLFANRKDVRLVDA-------ANSRNS-SVIISGLEDAAAVDFYYAENSVFWT--------DVSLEMIKRTYV------------------NGSQTSTNVIFGLLSPDGLALDWLGESETNRIEV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNLNGSCRLFWEHLDQPAIALDPLNGYMYWTDWG----------------------------ERP-KIERAGM-------DGSKQNRSV--------------IISERIHW---------PNGLTLD----YEDSKIYWADAKLNFIHSCNFDGSDRQ------PVVQGSLPH---PFALTLFEERLFWTDWTRAIHSCHKRT-----GGN---------REVVHS-----SPMDI---------------------HVYTAK--ASNNPCGNNNGGCS----------------------------------------------------------------HLCLMS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------QPPFFSCACPTG------------------------------VRCASSPILLLARRSDLRRISLDTPD----YTDVILQLSDRHTIAIDYDTVEDYVYWTDDEVHLIRRAHMD-GSGQEVIVSTEVEHPDGVAVDWIGRNLYWTDTGTDRIEVCRLNGTSRKVLISEGLVEPRAICLDPMRGHMYWTDWGAN-PKIERANMDGTERIALINSSLGWPNGVAIDYQEKKLYWGDAKTDMIEVANLDGTDRKVLVSNLPHIFGFSLLGDYVYWTDWQRRSIERVHKVTG----LMGLKAVNMNHVEG >XP_015132255.2 nidogen-2 isoform X1 [Gallus gallus] ---------VAALAAAAVAVAAALPTELLPYHGDGRLRHGDDESSPGVVLRPPMRLYGRAARRLFVGTNGVISTQDFPGETQYVDDDFPTDFPVIAPFLADLDTSGGRGDIYYRQDRAPTVLEWAAGYVHAGFPDTGTFVPSSAFIATWEDVGAHGE------PPGKLNTFQAILAYNEEETYAIFLYPEGGLQFLGTRPKESYNVQLELPARVGFSRGDGDDGKREGHSYSVASSQQELQRLEESNVGVPGVWVFRVGT-LENVEPGDV---PGAALSPAPDDTS-----------VPTEL-------------------------------QPGSRTTSPH----------------------------------------PALLSGLPASPLG-----QEWSPRLHSIGD----APQVSYSSGQHGVGVEEDVHFNTNVFTYSAGSRETCAQHHGRCSPHAFCTDYATGLCCHCRAAYYGNGRQCLPEGAVHRLNGKVSGSLVVGRTPVRFQDVDLHAYIVGSDGRAYTAISGVPAPAARALLPLLPLGGLFGWLFALEEPGSENGFSITGAEFTQYLEVTFYPGEEQVRITQMAEGLGADNYLSLRTHIEGQVPFVPENTSVHIAPYKELYHYSSSAVTSSAHRDYVLTSGSTNQTLSYRLRQNITVVCPHARTVQQLSVARAFALYDHEQVLRYALTSRISSSREVPPVNPCHDGTHACEETARCQPGTGLGYTCECAAGYRGCQDVDECEEGLGQCGPFSVCLNVLGSYRCECHSGYRPAEDGHGCVLPTPAADPCEVGRHPCAPRDRARCLPRAGGQPACECLPGYAGDGRVCSLNLCHPAAICYNTPGSFSCQCQPGYEGDGFQQLTPCEHVPQCDQGNYRPLQCHGSTGYCWCVDGEIAGTRTAPGSTPPRCGSEPSERPPTMCERWRQSLLEHYGGSPRGDQYVPQCDAHGHFTPLQHGDSGYCWCVDESGREIQGTRSEPGSPPPCLPSVAPPTVRPSPRPDVSPFLLYAQGQQIGYLPLNGTRLQKEAAKTLLSLHGSIVVGIDYDCREKTIYWTDVAGRTISRASLEPGAEPETIINSGLISPEGLAVDHLRRAMFWTDSGLDKIERAQLDGSERRVLFDTDLVNPRAITVDPVRGNLYWTDWNREAPKIETSTVSGANRRVLVNTDIGLPNGLTFDPFSKLLCWADAGTKKLECTFPDGAGRRIIHNNLNYPFSIISYASHFYHTDWRRDGVIAVNKETGHRSHLYGITAVYPYCPGA >XP_009426087.1 nidogen-2 isoform X1 [Pan troglodytes] GDRVAGRPVVLLLLPLLMSRAAALHDELFPHWGDQLLQEGDDESSAVVKLANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAMAPFLADIDTSHGRGRVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGPYFSLTSTEQSVKNLYLSNLGIPGVWAFHIGSPLDNVRPAAV-GDLSAAHSSVPLGRSFSHATALESDYNEDNLYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQPPDSHLSSPLESSTLDPHTKEGTSLGEGPDLKGQVEPWDERGTPAPPEVDRDSLATPPPYPENGPVPSEMDVPPAHPEEEIVLRSYPTPLSRGTYEVGLEDNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHLHVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGSENGFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVPANFTAHISPYKELYHYSDSAVTSTSSRDYSLTFGAINQTWSYRIHQNITYQCRHAPTTQQLNVDRVFALYNEERVLRFAVTNQIGPVKDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAAAGQARCVHHGGSTFSCACLPGYAGDGHQCTENRCHPAATCYNTPGSFSCRCQPGYYGDGFQSQTPCEHIPQCDQGNFLPLQCHGSTGFCWCVDPEVPGTQTPPGSTPPHCGPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDVTPFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRASLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIHNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQRSHLYGITAVYPYCPTG >XP_038443101.1 nidogen-2 isoform X1 [Canis lupus familiaris] GDRAARRLAPPLLLLLLLARAAALHGELFPYRGDQLLQEGDDESSAAVKLASPLHFYEAQFSYLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSQGRGRVLYREDTSLAVLGQAARYVRAGFPRTARFTPTHAFLATWEQVGAYEEATSRAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLELPARVGFCRGETDDLKREGPYFSLTSTEQSVKNLYQSNLGIPGVWAFHIGSPLDNIRPATIGGDLTKAHPSPPPEQSFRPEAALESDYTEDNLYYDENEGEVEYPPSEPEEAWNGHSSIDVSFQPPDSVPASPLESATLDPQTKEGRVLEGVPDLNGRVESSEQPGTPAPSEIESDSLDTPPPHPGRGAPLSEEDVPPAHPGGKEVLLNYSTPLGQGRQVLGVEDVIGSSTEVFTYNAANKETCEHNHRQCSRHAFCTDYTTGFCCHCQSRFYGNGKHCLPAGAPHRVNGKVSGHLRVGHLPVHFSDVDLHAYIVSNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSFTGATFTHDMEITFYPGEERVQITQTAEGLDPENYLSIKTNIQGQVPYIPANFTAHIAPYKEVYHYLDSAVTSTSSRDYSLIFGAINQTRSYRIYQNITYQCRHAPTTRQLNVDRVFALYTEESLLRFAVTNQIGPVEEPTPVNPCYDGSHTCDITARCHPGTDVDYTCECASGYQGCVDVNECATGSHHCGPNSMCVNLPGSYRCECRSGYELADDRHTCVLIAPPSNPCEDDSHTCAPAGQARCIYHGGSTFSCACLPGYTGSGHQCTENRCHPSATCYNTPGSFSCQCHPGYHGDGFQGLKPCEHIPQCDQGHFLPLQCHSSTGFCWCVDPEVPGTRTPPGSTPPHCRPEPTQRPQTVCERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTVRPVPRPDVTPFLLYAQGQQIGHLPLNGTKLQKDLAKTLLSLHGSIVVGIDYDCHERMVYWTDVAGRTISRASLQPGAEPETIINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERKALFHTELVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLEGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLNYPFSIVSYADHFYHTDWRRDGVISVNRDSGQRSHLYGITAVYPYCPAG >NP_001095535.1 nidogen-2 precursor [Bos taurus] GDQAAGWPALLLMLLLLLSRAAALHSELFPYRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLYRQDTSPGVLGLAASYVRTGFPLSAHFTPTHAFLATWEQVGAYEEAKRGAPPSGELNTFQAVLASDEFDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGPYFSLTSTEQSVKNLYHSNLGIPGVWAFHIGSPLDNVRPATIGGDLSKARPSAPLGQSFSHAVALEDDYTQDTLDYDENEEEIEYPPSEPAEASNGHSSVDVSLGAPDSDLASPEESSPLDPHTKERRLQGEAPDLKGRVKSSEQPGTPAPPETEGDSPAAPPPSPEGGAGPADQDALPAHPGGEAALPNYPPHLGQRGQVVGVEDDISSNTEVFTYNAANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKQCLPEGAPHRVNGKVSGHLLVGHTPVHFTDVDLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFYPGEERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFSAHVAPYKELYHYADSAVTCTSTRTYSLMSGAINQTQTYRIHQNITYQCRHAPVTQQLNVDRVFALYSEEKVLRFAVTNQIGPVEEPTPVNPCYDGSHTCATTARCHPATGVDYTCECASGYQGCVDVNECATGFHRCGPNSVCVNLLGSYRCECRSGYEFADDRHTCILITPPPNPCEDGHHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTENRCHPSATCSNTPGSFSCRCQPGYYGDGFQ---------------------------------------------------EPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHFTPLQHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTVRPTPRPDVTPFLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPEMVVNSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQNNLNYPFNIVSYADHFYHTDWRRDGVIAVNRDTGQRSHLYGITAVYPYCP-G >XP_020957573.1 nidogen-2 isoform X1 [Sus scrofa] GYRGARRPA-PLLLLLLLSRAVALQDELFPYLGDQLLQEGDDESSAAVKLALPLRFYDAQFSDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSHGRGRVLYREDTSPDVLSLAARYVRTGFPRSAHFVPTHAFLATWERVGAYEEPKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLELPARVGFSRGEVDDLKREEQYFSLTSTEQSVKNLYHSNLGIPGVWAFHIGSPLDNVKPAIAGGDLSKAHPSVPLRHSSSHAVAPEGEDTEDNLYYDENEEEVEYPPGETEEESNGHSPDDVSFHLPGSDLPSPLESATLDPQTKEGRPQEEAPDLKGRGETSEQPGAPAPPKTERDSPDALPPHPDEGALPAERDVPPVPSGGEVVLPNYPPPLGRGRQVVGVEDDIGSNTKVFTYNAANRETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDVDLHAYVVGNDGRAYTAISHIPQPAAQALLPLMPIGGLFGWLFALEKPGWENGFSLTGATFIHDMEVTFHPGGERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFTVHITPYKELYHYSGSAVTSTSSRAYSLTYGAINQTRSYSIHQNITYQCRHAPTTQQLNVDRVFALYTEEKVLRFAVTNQIGPVEEPAPVNPCYDGSHTCATTAQCHPATGVDYTCECASGYQGCVDVNECATGFHRCGPNSVCVNLPGSYRCQCRSGYEFVDDRHTCVLIAPPPNPCEDGSHNCAPTSQARCIHHGGRSFSCACLPGYAGDGHQCAENRCHPSATCSNTPGSFSCHCQPGYHGDGFQGLKPCEHIPQCDQGHFLPLQCHGSTGFCWCVDPEVPGTRTPPGSLPPHCGPEPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHFTPLQHGKSDFCWCVDQDGREVQGTRSQPGTTPACIPTVAPPTMRPTPRPDVTPFLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPETIVNSGLISPEGLAIDHFRGTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIRGNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLNYPFSIVSYADHFYHTDWRRDGVISVNRDSGQRSHLYGITAVYPYCPTG >XP_008267875.2 PREDICTED: LOW QUALITY PROTEIN: nidogen-2 [Oryctolagus cuniculus] RTLGRQRPRWARRGPLLPRRRPWTWAPGSPDAG-----AAEDEGSAQPRPAA-------------------------ASPSPYVDDDLPXDFPAIAPFLADIDTSGGRGRVLYRQDSSPAVLGLAARYVSAGFPRAAPFSPTHAFVATWDQVGAYEEVRRGAAPSEELNTFQAVLVSDESDAYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEADDLKREGQYLSLTRTEQSVKNLYLSNVGIPGLWAFHIGSPLDNVRPAAVGGALPAAHSSTPLKHPFSHAVALKADHPEDSLYYDENEEEVEYPPAEPEAA-----TVDIAFHPPDSDLASPLESTTGEPPSKQEARLQESPERRPGAQPLGQTGAVAVPAVDGDSVAAPTRYPDD---------------AGDTLPRYSAPVGGGRYVAGVEEDITSNAEVFTYNAAHKETCERNHGQCSAHAFCTDYTTGFCCHCQSSFYGDGKHCLPEGAPHRVNGKVSGHLRVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPPPAAQALLPLTPLGGLFGWLFALEKPGSENGFSLTGATFVQDTEVTFYPGEERLRITQTAEGLDPENYLSMKTSIQGQVPYVPANSTAHLAPYKEIYHHSDSAVTSTSSRDYYLTFGAVNQTGSYRIHQNITYQCRHAPAAQQLTVDRVFALYSEEGVLRFAVANQIGPVEDPAPVNPCYDGSHTCDMTARCHPGPGTHYTCECTPGYQGCVDVNECATGFHRCGPNSMCVNLPGSYRCECRSGYTFADDQHTCILMAPPPNPCENGTHTCAPAEQARCIPHGDGTFSCACLPGYAGDGHQCSENSCHPAATCYNTPGSFSCHCQPGYLGDGFQGLKACQHIPQCDQGDFLPLQCHGSTGFCWCVNSEVPGTRTPPGSTPPHCGPGPTQRPRTVCERWKESLLEHYGGTARDDQYVPQCDDLGRFVPLQHGKSDFCWCVDKDGREVAGTRTQPGVTPTCLPEAVPPLIGAMPRPEDS-FLVYAQGQRLGRLPFKRTKLLKDQASTLLSMHGSIIVGLDYDCHERKVYWTDVAGRVISRIGMQPGAEPEVIINSGLLRPEGVAIDFIHRTMYWTDSGLDQIVRTNLDGSEREILFYVDLVNPRAITVDPVGGNLYWTDWNRDAPKIERSSLDGTGRRILIGKDIGLPNGLNFDPVTEMLCWADAGTRKLECTLRDGTGRRVIQSNLNYPFSMVSYIDHFYYTDWRRDAVISVNANTGQRSHLYGITAVFPYCPTG >XP_002824786.2 nidogen-2 isoform X1 [Pongo abelii] EDRVAGRPAVLLLLPLLMSRSAALHDELFPHWGDQLLQEGDDESSAVVKLANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRGRVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWKQVGAYEEVKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGPYLSLTSTEQSVKNLYLSNLGIPGVWAFHIGSLLDNVRPAAV-GDLSAAHSSVPLGRSFSHATALESDYNEDNLYYDVNEEEAEYLPGELEEALNGHSSIDVSFQ----------ESSTLDPHTKEGTSLGEGPNLKGQVEPWDERGTPAPPEVDRDSLATPPPYPENGPVPSEMDVPPAHPEEEIVLRNYPTPLSRGTYEVGLEDNIGSNTEVITYNAANKETCEHNHRQCSWHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHLHVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGSENGFSLAGAAFTHDMEVTFYPGEERVRITQTAEGLDPENYLSIKTNIQGQVPYFPANFTAHISPYKELYHYSDSAVTSTSSRDYSLTFGAINQTWSYRIHQNITYQCRHAPTTQQLNVDRVFALYNEERVLRFAVTNQIGPVKDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITRPANPCEDGSHTCAPAGQAQCIHHGGSMFSCACLPGYAGDGHQCTENRCHPAATCYNTPGSFSCRCQPGYYGDGFQSLTPCEHIPQCDQGNFLPLQCHGSTGFCWCVDPEVPGTQTPPGSTPPHCGPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTIAPPTARPTPRPDVTPFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRASLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRHVIQNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQRSHLYGITAVYPYCPTG >XP_010710486.1 nidogen-2 [Meleagris gallopavo] GERREERSSPARPQLAAIPAPGAAP-----YRGMGMREEEEKGGREGRT--TPGRILGRAARRLFVGTNGVISSQDFPGETQYVDDDFPTDFPVIAPFLADLDTSGGRGDIYYRQDHTPSVLEQAAGYVHAGFPYTGTFVPSSVFVATWEDVGAHGE------PPGKLNTFQAILAYNEEDTYAIFLYPEGGLQFLGTRPKESYNVQLELPARVGFSRGDGDDGKREGHSYNVASSQQELQRLEESNVGMPGVWVFHVST-LENVEPRNG---PGAALSSAPDDTS-----------VPTEL-------------------------------QPGSRTTSPH----------------------------------------PALLSGLPASPLG-----QEWSPRLH-FGD----APQVSYSSGQHGVGVEEDVHFNTNVFTYSAGSRETCAQHHGRCSPHAFCTDYATGLCCHCRAAYYGNGRQCLPEGAVHRLNGKVSGSLVVGRTPVRFQDVDLHAYIVGSDGRAYTAISGVPAPAARALLPLLPLGGLFGWLFALEEPGSENGFSITGAEFTQYLEVTFYPGEEQVHITQTAEGLGADNYLSLKTHIEGQVPFVPESTSVHIAPYEELYRYSSSAVTSSAHRDYVLTSGSTNQTLSYRLHQNITVTCPHARTVQQLSVARAFALYDHEQVLRYALTSRISSTHEVPPVNPCHDGTHACEETARCQPGTGLGYTCECAAGYRGCKDVDECEEGLSQCGPFSICLNVPGSYRCECHSGYRPAEDGHGCVLPTPAADPCEVGRHPCAPRDRARCLPRAGGQPACECLPGYAGDGRVCSLNLCHPAATCYNTPGSFSCQCQPGYEGDGFQQLTPCEHVPQCDQGNYRPLQCHGSTGYCWCVDSEIAGTRTAPGSTPPRCGNEPSERPPTMCERWRQSLLEHYGGSPRGDQYVPQCDAQGHFTPLQHGDSGYCWCVDESGREIQGTRSEPGSPPPCLPSVAPPSIRPSPRPDVSPFLLYAQGQQIGYLPLNGTRLQKEAAKTLLSLHGSIVVGIDYDCREKTIYWTDVAGRTISRASLEPGAEPETIINSGLISPEGLAVDHLRRAMFWTDSGLDKIERAQLDGSERRVLFDTDLVNPRAITVDPVRGNLYWTDWNREAPKIETSTVSGANRRVLVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECTFPDGAGRRIIHNNLNYPFSIISYASHFYHTDWRRDGVIAVNKETGHRSHLYGITAVYPYCPGA >XP_008955315.2 nidogen-2 isoform X1 [Pan paniscus] GDRVAGRPVVLLLLPLLMSRAAALHDELFPHWGDQLLQEGDDESSAVVKLANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAMAPFLADIDTSHGRGRVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGPYFSLTSTEQSVKNLYLSNLGIPGVWAFHIGSPLDNVRPAAV-GDLSAAHSSVPLGRSFSHATALESDYNEDNLYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQPPDSHLSSPLESSTLDPHTKEGTSLGEGPDLKGQVEPWDERGTPAPPEVDRDSLATPPPYPENGPVPSEMDVPPAHPEEEIVLRSYPTPLSRGTYEVGLEDNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHLHVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGSENGFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVPANFTAHISPYKELYHYSDSAVTSTSSRDYSLTFGAINQTWSYRIHQNITYQCRHAPTTQQLNVDRVFALYNEERVLRFAVTNQIGPVKDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTENRCHPAATCYNTPGSFSCRCQPGYYGDGFQSQTPCEHIPQCDQGNFLPLQCHGSTGFCWCVDPEVPGTQTPPGSTPPHCGPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGLFIPLQHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDVTPFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRASLELGAEPETIVNSGLISPEGLAVDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIHNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQRSHLYGITAVYPYCPTG >XP_023111456.1 nidogen-2 [Felis catus] GDRA-----LPLLLLLLLSRAAALRDELFPYWGDQLLQEGDDESSAAVKLASPLRFYEAQFSYLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSQGRGQVLYREDTSRAVLDLAARYVRSGFPRTAHFTPTHTFLVTWKQVGAYEETTRRAPPSEERNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLELPARVGFCRGEVDDLKREGPYFSLTSTEQSVKNLYQSNLGAPGVWAFHIGSRLDNIRPATVGGDLSKGHSAAPPERSFGLPEVLASDYTEDNLYYDENENEVEYTPSEPEEALNGHSSVDVSFQPPNSDLASPLESATLNPQPKEGRHPWGTPDLNVRVESSEQPGTPAPSEVEGESLDTLPPYPENGAPPSEADVPPALPEGKVVLLNYPIPLGRGRQVLGVEDVITSNTEVFTYNAADKETCERNHGQCSPHAFCTDYTTGFCCHCQSRFYGNGKHCLPEGVPHRVNGKVSGHLRVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFRLTGATFTHDMEVIFYPGEERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFTAHMAPYKELYHYTDSAVTSTSSRDYSLILGGINQTLSYRIYQNITYQCRHAPKTQQLNVDRVFALYTGEGVLRFAVTNQLGPVETPTPVNPCFDGSHTCDTKARCHPGTGVDYTCKCASGYQGCVDVNECATGFHHCGPNSVCTNLPGSYSCDCRSGYEFADDHHTCILIAPPPNPCADGSHSCAPADQARCIYHGGSTFSCTCLPGYTGNGHQCTENRCHPSATCYNTPGSFSCRCLPGYHGDGFQGLKPCEHIPQCDQGHFLPLQCHGSTGFCWCVDPEVPGTRTPPGSTPPHCGPEPTRRPRTVCERWRENLLEHYGGTPRDDQYVPQCDDLGHFTPLQHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPTARPLPRPDVTPFLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRAISRASLEPGAEPETIISSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERKALFHTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLEGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNHLNYPFSIVSFADHFYHTDWRRDGVISVNRDSGQRSHLYGITAVYPYCPTG >XP_004010577.3 nidogen-2 [Ovis aries] ADRAAGRPALLLMLLLLLSRAAALHSELFPYRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLYRQDTSPAVLGLAANYVRTGFPLSAHFTPTHAFLATWEQVGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGPYFSLTSTEQSVKNLYHSNLGIPGVWAFHIGSPLDNVRPATVGGVLSKAHPWAPLGQSFSHAVALEDDYTQDTLEYDENEEEIEYPPSEPAEASNGHSTIDVSLGAPDSDLASPVEASPLDPHTEERRPQGEAPDLKQRVESSQQPGTPAPPETEGESPAAPPPSLEGGAGPADQDALPAHPGGEAALPNYPPHLGHRRQVVGVEDDISSNTEVFTYNAANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDVDLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFYPGEERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHHADSAVTSTSTRTYSLMSGAINQTQSYRIHQNITYQCRHAPVTQQLNVDRVFALYSEEKVLRFAVTNQIGPVEEPTPVNPCYDGSHTCATTARCHPATGVDYTCECASGYQGCVDVNECATGFHRCGPNSVCVNLLGSYRCECRSGYEFADDRHTCISITPPPNPCENGRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTENRCHPLATCSNTPGSFSCRCQPGYYGDGFQ---------------------------------------------------EPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHFTPLQHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTSRPTPRPDVTPFLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPEMVINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQSNLNYPFNIVSYADHFYHTDWRRDGVIAVNRDTGQRSHLYGITAVYPYCP-G >XP_011482732.1 nidogen-2 [Oryzias latipes] ---------SLLCWSCG--AVTAIRADLFPFSGDSLLAEGDDETSKVLILPKPFYFYNSQFSLLYVATNGIVSAQDLPMEKQYVDDGFPTDFPVVAPFLADIDTSGGRGQIYYRVTETPSVLNRLTWEVSRGFPD-AKFTPTHAVVATWENVAAYEEPSRSSGSSNRVNTFQAVIAYDETDSYVLFLYPEDGLNFFGTRPKESYNVEIELPARVGFSRGEVTYFRSEGPSYSVTSDEQSVKNLNVGNTGTPGLWLFHTGHSFDNVIPASVGGPIVTAPPR--PDTTTPEYEVIY------TLGPEIH-EDDEYSLTGRGP-------------SNHFQYLQPG--VLLGSEPR-----------------------------YGPEPAAPPEQPQRGARQGQEQIPQLPLE---VVDLYP---TPGGYVVNVEDDVHFDTRVIQYTTDNKETCARFQQQCSQNAFCSDYATGFCCHCQPGFYGNGRDCLPEGAPQRVSGKVSGTVSVQSTPVTLNNIDLHAYIVVGDGRAYSAISEVPEPLGWALMPVSPIGELFGWLFALELPNSQAGFKSTGAKFTRHAEVQFYPGNHRLSILQTGRGLDEHNLLNVDTVVSGNVPFIPPEAEITVEPFKETYQYYPSVVTSTSAREIKVVSSRGAESYSLNLKQNITYRCRHDNETLQITMERVFVMYDDERILRYAVTNKIGPVGAPELINPCYSGNHDCDTTAMCIPQEDQNYECQCATGYGGCYDIDECAEGVSSCGEHSECLNLPGSHRCLCSRGFEFAYDGRTCV------------------------------------------------SSPCHINARCINELGSFQCLCQPGFTGDGFFPKTPCEFVPQCDEGRYLSQQCHGSTGHCWCVDSERPGTRTPPGVAQVDCYQPPYTRPESVCERWRASLMEHYGGKPQPQQYLPQCRSDGEFSPVQYGETTYCWCVDQDGREIDGTRSHDAVKPACLSSVAPPTVLPLPRPDVTPTLLYAQGQKIDALPLNGTKLHANGSKTLLTLHGSIVVGIAYDCRENQVYWTDLSARTINRASLVSGSEPEILISSNLESPEGLAVDVQRRLMFWVDSSPDNIEVANLDGSERRTLFDTDLVNPRAIIVVSSKGTLYWTDWNREAPKIECSTVNGQNRRVVVSDGVGLPNALAYDHATDQVCWADAGTKRLECVSPNGSGRRVIHRNLNYPFSMVYYRDHFYYTDWRRDGVIAVNRDSNQRSHLYGIAVATNHCLQG >XP_013223751.1 nidogen-2 isoform X1 [Columba livia] ------REG-------VVSRLSTLC------WG----THGRG-TSAAPEHLVPL--------SLQVGTNGVISTQDFPRETQYVDDDFPTDFPVIAPFLADLDTSGDRGNIYYRQDDSPDVLHQAAGYIQAGFPHIGSFMPTNAFIATWEDVGAYQELSQDTKPSQKLNTFQAVVAYDDEDTYAIFLYPKGGLQFLGTRPKESYNVQLELPARVGFSWGDGDDPKRDGLFHSLASSERALRLLEESNTGIPGVWVFHVGSPLEHVEPGGGGGAPGVPQSPEPDTAGYTHALYSHADHVATNL-------------------------------RHGSAAMSPH----------------------------------------PTLLGGLPVSPSG-----QERSRRLHLDGDVTQQSYSSSYSSGHHGVGVEEDVHFNPDVFTYSAASKETCARHHGRCSPHAFCTDYATGVCCHCQATYYGNGRQCLPEGAVHRLNGKVSGSLMVGRMSVSFQDVDLHAYIVGSDGRAYTAITGVPQPAGRALLPLLPLGGLFAWLFALEDPGSENGFSITGAEFTQSLEVTFYPGGETVRVTQTAEGLGPDNYLSLKTHIQGQVPFLPENVTVHITPYKELYHYSSSVVTSSAQREYVLAAGTANQTLSYRLRQNITFSCPHTRAQQRLSVARAFALYDHEHVLRYALAARIGSAPENPLVNPCHDGTHRCEAPARCQPGTGMEYTCECVAGYRRCRDVDECAEGLSQCGPFAICLNAPGSYRCECRSGYQPAGDGQMCVPLVPATDPCEDGSHPCAPPDRARCLSHAGGHPTCECLPGYAGDGIYCSENPCHPAATCYNTPGSFSCQCPPGYEGDGFQRLTPCQHVPQCDDGGYRPLQCHSSTGHCWCVDAEIAGTRTAPGSTPPRCGNEPTERPRSMCERWRQSLLEHYGGSPRRDQYVPQCEAGGEFTPLQHGDSGYCWCVDESGREIPGTRSEPGSTPPCLPSVAPPSVRPSPRPDVSPFLLYAQGQQIGYLPLNGTRLQKEAAKTLLSLHGSIVVGIGYDCREKTIYWTDVAGRTISRASLEPGAEPETIISSGLISPEGLAVDHLRRAIFWTDSGLDKIERARLDGSERQVLFDTELVNPRAIAVDPVRGNLYWTDWNREAPKIETSTVNGANRRVLVNRDIGLPNGLTFDPFSKLLCWADAGTKHLECTFPDGTGRRIIQNNLNYPFSIISYANHFYHTDWRRDGVIAIDKETGQRSHLYGITAVYPYCPGA >XP_017909832.1 PREDICTED: nidogen-2 [Capra hircus] ADRAAGRPALLLLLLLLLSRAAALHSELFPYRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLYRQDTSPAVLGLAANYVRTGFPLSAHFTPTHAFLATWEQVGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGPYFSLTSTEQSVKNLYHSNLGIPGVWAFHIGSPLDNVRPATVGGVLSKARPWAPLGQSFSPAVALEDDYTQDTLEYDENEEEIEYPPSEPAEASNGHSAIDVSLRAPDSDLASPVEASPLDPHAEERRPQGEAPDLKQRVESSQQPGTPAPPETEGESPAAPPPSLEGGAGPADQDALPAHPGGEAALPNYPPHLGHRRQVVGVEDDISSNTEVFTYNAANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDVDLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDAEVTFLPGEERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYADSAVTSTSTRTYSLMSGAINQTQSYRIHQNITYQCRHAPVTQQLNVDRVFALYSEEKVLRFAVTNQIGPVEEPTPVNPCYDGSHTCATTARCHPATGVDYTCECASGYQGCVDVNECATGFHRCGPNSVCVNLLGSYRCECRSGYEFADDRHTCISITPPPNPCENGRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTENRCHPLATCSNTPGSFSCRCQPGYYGDGFQ---------------------------------------------------EPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDDLGHFTPLQHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTIRPTPRPDVTPFLLYAQGQQIGHLPLNGTRLQKDTAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPEMVINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERRVLFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECIFPDGTGRRVIQNNLNYPFNIVSYADHFYHTDWRRDGVIAVNRDTGQRSHLYGITAVYPYCP-G >XP_014375969.1 nidogen-2 [Alligator sinensis] ---------------------------------------------------------------------------------------------------TDVNKTLGTRR--------RAVLSRAAGYIRAGFPS-TAFAPTRAVVATWEDVGAYEEVSRDAEPSRQRNTFQAVLAYDHADAYALFLYPDDGIQFFGTRPKESYHIQLELPARVGFSRGETDP-RRENLHYSVASSEQGLKNLYSSNVLTPGVWVFHIGSPLENIVPAGAARQLGGALPTGP--ESASHHATAEHDYPDGAFSYDENEEDEEFPFVEPTEVAEDYDELGISLHQEGLEFASKLRPVPSQE--------------------------PSSLETDEDLLEESPTYRQRGAIPAETDVHLGYPEGEVVLQSYPLPFPRGRHIVGVDEDISFNTDVFTYSAASQETCEQHHGLCSPHAFCTDYATGFCCHCQTKFYGNGRHCLPEGAAHRLNGKVSGNLLVGRTPVHFADVDLHAYVVGNDGRAYTAISRIPQLAARALMPLTPIGGLFGWLFALEKPGYENGFSITGAEFTHSLEATFYPGEETVHITQTAEGLGLENYLSLRTRIQGRVPYIPENFTVHIAPYKELYYYSSSAVTSTSHREYSLLFGHHNQTLSYRLHQNVTFRCPHARATQQLSVERVFALYNEEQVLRYAVTNQIGSAEDTAVVNPCYDGTHVCDTTARCQPGAGLQYSCECTAGYCGCMDIDECAEGESRCGPFSVCLNSLGSYRCECQHGYRLTDDRRTCVLAAPPPDPCAAGRHSCAAADQARCIPRGGGAFSCECLPGYTGDGHNCSQGRCHPAATCLNTPGSFSCQCRPGYDGDGFQRLTPCEHIPVCDQGNYHPLQCHSSTGFCWCVDEEITGTRTPPSSTPPRCGEEPTVRPQTMCERWRQSLLDHYGGRPREDQYVPQCDTAGSFSPLQHGNSGFCWCVDEHGREIHGTRSEPGTAPPCLPSVAPPTVQPSPRPDVSPFLLYAQGHQIGYLPLNGTRLQKEAAKTLLALHGSIVVGIDYDCRGKMVYWTDVAGRTVNRASLEPGAEPETVINSGLMSPEGLVVDHLRRAMFWTDSGLDKIERANLDGSQRRALFSTDLVNPRAITVDPIRGNLYWTDWNREAPKIETSTVEGANRRILVNEDIGLPNGLTFDPFSKLLCWADAGTKKLECMFPDGTGRHVVQNNLNYPFSIVSYANHFYHTDWRRDGVIAVNKDTGQRSHLYGITAVYPYCPGV >XP_015807982.1 PREDICTED: nidogen-2 isoform X1 [Nothobranchius furzeri] SSGAAGPSSALLYWSCGVCVVSALHTDLVSYSGDLILAEGDDETSRVLTLPRPLYFYDTPFHQLYVATNGIISAQDLPMEKQYVDDGFPTDFPVVAPFLADIDTSGGRGHIYYRVTETPSVLNRVAQEVRRGFPD-AKFAPTHAVVATWENVAAYEDQTQGTELSNKVNTFQAVIGYDETDSYTLFLYPEDGLNFFGTQPKELYNVKIELPARVGFSRGEVTFFRSEGPFYSVTTDEKSVKRLSVGNTGIPGVWLFHTGNSFENIIPAAIGGLLSTLPPEGHPDTTTPEYG----DYPDNTFESESPEEVDGYTATGKDL----------EFQGGDSGSLQPG--VTYN----------------------------------GEEGEVPPNHPER-AQQLQEQKPQLPLE---VVEVNPPPLSPGGYVVSVEEDVDFDTGVIQYTTENKETCARFQQQCSQNAICSDYATGFCCHCRPGFYGNGRQCLPDGAPQRVSGKVSGTVTVGSFPIVLDNIDLHAYIVVGDGRAYTAISQVPEPVGWALMPVSPVGELFGWLFALELPNSQAGFKTTGAEFTRHAEVLFNPGNQRLSIIQTGSGLDEHNHLRVETIVSGHVPLLPPGAEVTVQPFKETYQYYPSVITSSSVREFVVVSERGSQSYTFHLKQNITYRCRHDNETLQITMERVFVMYVEERILRYAITNKISPVGDDELLNPCYVGNHDCDTTAQCIPLEGQAFKCQCATGYTGCYDIDECAEGSDLCGDHSQCLNLPGSHRCQCWEGFEMAFDGRNCV------------------------------------------------SSPCHINARCINDLGSFRCHCQPGFHGDGFYPKTHCEYVPQCDKGQYIPLQCFGSTGHCWCVDPERPGTRTPPGTPPKDCAKASTSRPESVCERWRASLMEHYGGKPDPQQYLPQCEPAGEFSPVQYGHTTYCWCVDENGREVPGTRSHDVVKPACLPSVTPPTARPLPRPNVTPTLLYAQGQKIGALPLNGTRLDSSRSRTLLTLHGSIVVGIAYDCKENQVYWTDLSARTINRASMVSGAEPEILINSNLVSPEGLAVDVKRRLMFWVDSSPDVIESANLDGSRRRILFDTDLVNPRAIIVVSSTGTLYWTDWNREAPKIESSSVDGLNRRVVVSDGVGLPNALTYDSSSGQVCWADAGTKRLECISPNGSGRRVIHPTLNYPFSMVYYRNHFYYTDWRRDGVIAVSKDSSQRSHLYGVTIATTYCLPG >XP_030857550.1 nidogen-2 isoform X1 [Gorilla gorilla gorilla] GDRVAGRPVVLLLLPLLMSRAAALHDELFPHWGDQLLQEGDDESSAVVKLENPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRGRVLYREDTSPAVLGLAARYVLAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELNTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGPYFSLTSTEQSVKNLYLSNLGIPGVWAFHIGSPLDNVRPAAV-GDLSAAHSSVPLGRSFSHATALESDYNEDNLYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQPPDSHLSSPLESSTLDPHTKEGTSLGEGPDLKGQVEPWDERGTPAPPEVDRDSLATPPPYPENGPVPSEMDVPPAHPEEEIVLRNYPTPLSRGTYEVGLEDNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGSGKHCLPEGAPHRVNGKVSGHLHVGLTPVHFTDVDLHAYIVGNDGRAYTAISDIPQPAAQALLPLTPIGGLFGWLFALEKPGSENGFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVPANFTAHISPYKELYHYSDSTVTSTSSRDYSLTFGAINQTWSYRIHQNVTYQCRHAPTTQQLNVDRVFALYNEERVLRFAVTNQIGPVKDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTENRCHPAATCYNTPGSFSCRCQPGYYGDGFQSLTPCEHIPQCDQGNFLPLQCHGSTGFCWCVDPEVPGTQTPPGSTPPHCGPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDVTPFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRASLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQRSHLYGITAVYPYCPTG >XP_030265795.1 nidogen-2 isoform X1 [Sparus aurata] ---------CVLCWSCSVRVVTAIQADMFPYSGDMILAEGDDETSRVLSLPRPVYFYDSLFSQLYVATNGIVSAQDLPMEKQYVDDGFPTDFPVVAPFLADIDTSGGRGQIYYRVTETPSVLNRVAQEVHRGFPD-AKFTPTHVVVATWENVAAYEEPTRTSGPSNKFNTFQAVIGYDEVDSYVLFLYPEGGLNFFGTRPKESYNVEIELPARVGFSRGEVTYLRTEGPHYSVTSDEQSVKNLYVGNTGIPGVWLFHTGNSFDNIVPASVGGLLATPPTRGHLDTTTPDYPEFE-EYPDNTFDPDSQDEEDDYPLTGGDA----------EFQSDHSEAPQPA----------------------------------------GSQPSAPPNPPEA-----EEQQPQVPLE---VVDVYPPPLSPGGHVVSVEDDVDFDTGVIQYTTENKETCARFQQQCSQNAFCSDYATGYCCHCRPGFYGNGRHCLPEGAPQRVSGKVSGTVTVGSTPVDLNNIDLHAYIVVGDGRAYTAISEVPEPVGWALMPVAPIGELFGWLFALELPNSQAGFKITGAEFTRRAEVIFYPGNQRLSIIQTGRGLDDHNHLTVDTVLSGSVPFLPPGAEVTMDPFKETYQYYPSVATSTSVREYSVVSDRGSESFSFQLKQNITYRCRHDSETLQITMERVFVMYVEERILRYAITNKISPVGGPELVNPCYAGTHDCDTTAQCIPQEGQAFRCQCATGYRGCYDIDECAEGLSTCGAHAQCMNLPGSHRCQCQSGFEFGFDGRTCV------------------------------------------------SSPCHVDARCINGLGSFQCQCQAGFYGDGFYPKTHCEYVPQCDNGQYTPLQCHSSSGHCWCVDRERAGTRTPPGTAPKDCDRVPTQRLESVCERWRSSLIEHYGGKPEPQQYLPQCEPDGQFSPVQYGETTYCWCVDQDGREVPGTRSHDVVKPACLPSAAPPTVRPLPRPDVTPTLLYAQGQKIGALPLNGTRLDATRAKTLLTLHGSIVVGIAYDCRENRVYWTDLSARTINRASMAPGAEPEILINTNLVSPEGLAVDVKRRLIFWVDSNPDMIESANLDGSGRRTLFDTDLVNPRAIIVVSSSGTLFWTDWNREAPKIESSSVDGQNRRVVVSDGVGLPNALTFDSSSGQVCWADAGTKRLECVSPDGSGRRVIHSSLNYPFSMVYYRNHFYYTDWRRDGVIVVSKESSQRSHLYGIAIATSQCLSG >XP_040188888.1 nidogen-2 [Rana temporaria] ---------ILHWHCLLLGFSAAISQELFPYRGDRLLPDGDDETSEVVTLTQPILFYEADFKELYVGTNGIISTQDFPRETQYVDDGFPTDFPVIAPFLSDIDTSNGKGKIYYRQDNSPDILSTVARQVDRGFPQ-AAFSPTNVFMVTWDNVGAYEEVTRHAEPSNKLNTFQAVLAYDDSDTYAIFLYPEHGLQFFGTRPKESYNVHLDLPARVGFSRGDSEMLKKEAPFYSVTSSEQSVKNLYTSNVGVPGVWVFHIGSEIDNVIPAKVPHHHPQQR-FVPSHNDFPEQQQQQQLENQFNGNYEDNYEDEDYPAGQTTEPTTDSAVLNPDRTEDHATLYTPN--TPYNPDE-------------PLVEPEIQRSE---SRVLGNIPSEEPSESVS----NNVTPNPVDPQRSDV--------YRSNRFYGNEEVGGLDTDVLTFNPVSRETCDRKPGYCSPYAFCTDYATGFCCHCQDSYYGNGVHCLPKGAPHRVNGKVSGNLLVGQRPVTFDGIDMHAYIVVNDGRAYTAISQVPEPASWSLTPLTAIGGLFGWLFALEKPGHQNGFSITGAKFVHNLEAVFSPGEEVIHVTQTADGFDSDNYIHVRTTIKGKIPYIPETSTVQIAPYYEIYQHSGSVVTSTAYREYTVTSSGDVQKFSYRLKQNITYQCGHAQTAQKLSVDRVFAMHNDEKVLRFAITSHIGSLHEPTQGNPCFDGTHQCDTRAQCQPATGLNYSCVCASGYRGCTDYDECEDQLDNCGQNTRCVNLPGSFRCECVPGYVFSADGQNCILGSSFGNPCEDGTHSCD-LTTSQCVPRGDGVFTCECFPGYTRSGQSCIERRCHPDATCANVPGSFSCRCNPGFTGDGFQPSTPCLFLPECDEGNYVPLQCHGSTGHCWCVDREIEGTRRPAGSGRPQCGIEPTQRPQTMCERWKQSLVDHYGGSPSAEHYIPQCDAYGEFSPLQHGNSGYCWCVDKDGREIEGSRTQPGMTPACLPSVAPPTVRPTPRPDVTPYLLYAQGQQIGYLPLDGVKFRKDKARTLLALHGSIVVGIDYDCQEKKVYWTDVSGRTISRAGLEPGAEPEVLISTDLMSPEGLAIDYLRKTMFWTDSGTDKIESARLDGTFRKTLFDTNLVNPRAITVDAVRGNLYWTDWNREAPKIETSYVDGSNRRILVNDNIGLPNGLTFDPFSKQICWADAGTKKLECILSDGSGRRVIQSNLNYPFSVVGFANHFYHTDWRRDGVISINKENGQRSHLYGITAIYPYCPSG >KYO47226.1 nidogen-1 [Alligator mississippiensis] -----------------LHRCRRGGPRLFPHRGDRALPPGDDEGS-ALPLAPLLPFYGLRLARLHVGTNGLLSGQDFPRETQYVDDDLPTDFPAIAPFLADLDTSGGRGQIYYRQDGASDVLSRAAGYIRAGFPS-AAFAPTHAVVATWEDVAAYEAVSRDAEPSRQRNTFQAVLAYDHADAYALFLYPDDGIQFFGTRPKESYHIQLELPARVGFSRGETDP-GRENLHYSVASSEQGLKNLYSSNVLTPGVWVFHIGSPLENIVPAGAGRQLGGALPTAP--ESVSRHATAEHDYPDGAFSYDENEEDEEFPFVEPTEVAEDYDELGISLH-------------------------------------------PSSLETDEDLLEESPTYRQRGAVPAETDVHLGYPEGEVVLQSYPLPFPRGRHIVGVDEDVSFNTDVFTYSAASQETCEQHHGLCSPHAFCTDYATGFCCHCQTKFYGNGRHCLPEGAAHRLNGKVSGNLLVGRTPVHFADVDLHAYVVGNDGRAYTAISRIPQLAARALMPLTPIGGLFGWLFALEKPGYENGFSITGAEFTHSLEATFYPGKETVHITQTAEGLGLENYLSLRTHIQGRVPYIPENFTVHIAPYKELYYYSSSAVTSMSHREYSLLFGHHNQTLSYRLHQNVTFQCPHARATQQLSVERVFALYNEEQVLRYAVTNQIGSAEDTAIVNPCYDGTHVCDTTARCQPGAGLQYSCECTAGYRGCVDIDECAEGESRCGPFSVCLNSLGSYRCECQHGYHLADDRHTCVLAAPPPDPCAAGRHSCAAADQARCIPRGGGAFSCECLPGYTGDGHNCSQDRCHPAATCLNTPGSFSCQCRPGYDGDGFQRLTPCEHIPVCDQGNYQPLQCHSSTGFCWCVDEEIAGTRTPPGSTPPRCGEEPTARPQTMCERWRQSLLDHYGGRPREDQYVPQCDAAGSFSPLQHGNSGFCWCVDEHGREIHGTRSEPGTAPPCLPSVAPPTVQPSPRPDVSPFLLYAQGHQIGYLPLNGTRLQKEAAKTLLALHGSIVVGIDYDCRGKMVYWTDVAGRTVNRASLEPGAEPETVINSGLMSPEGLVVDHLRRAMFWTDSGLDKIERANLDGSQRRALFSTDLVNPRAITVDPIRGNLYWTDWNREAPKIETSTVEGANRRILVNEDIGLPNGLTFDPFSKLLCWADAGTKKLECTFPDGTGRHVVQNNLNYPFSIVSYANHFYHTDWRRDGVIAVNKDTGQRSHLYGITAVYPYCPGA >XP_043327612.1 nidogen-2 [Cervus canadensis] GDPAAGRPA-LLLMLLLLSRAAALHSELFPYRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLFRQDTSPAVLGLAASYVRAGFPLSAHFTPTHAFLATWEQVGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGPYFSLTSTEQSVKNLYHSNLGIPGVWAFHIGSSLDNVRPATVGGDLSKARPSAPLGQSFSHAVALEDDYTQDPLDYDENEEEIEYPPSEPAEASNGYSSVDVSLRAPDSDLASPVESSPLDPHTKERRPQGEASDLKGQVESSEQPGTPAPPETEGESPAAPPPSPEGGAGPADQDALPAHPGGEAALPNYPPHLGHRRQVVGVEDDISSNTEVFTYNAANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDVDLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFYPGEERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYADSAVTSTSTRAYSLMSGAINQTRSYRIHQNITYQCRHAPITQQLNVDRVFALYSEEKVLRFAVTNQIGPVEEPTPVSPCYDGSHTCATTARCHPATGVAYTCECASGYQGCVDVDECATGFHRCGPNSVCVNLLGSYRCECRSGYEFADDRHTCILITPPPDPCEDGRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTENRCHPSATCSNTPGSFSCRCQPGYYGDGFQ---------------------------------------------------EPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDGLGHFTPLQHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTIRPTPRPDVTPFLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPETVINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQNNLNYPFNIVSYADHFYHTDWRRDGVIAVNRDTSQRSHLYGITAVYPYCP-G >KAF4017381.1 hypothetical protein G4228_009148 [Cervus hanglu yarkandensis] -------------MLLLLSRASALHSELFPYRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLFRQDTSPAVLGLAASYVRAGFPLSAHFTPTHAFLATWEQVGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGPYFSLTSTEQSVKNLYHSNLGIPGVWAFHIGSSLDNVRPATVGGDLSKARPSAPLGQSFSHAVALEDDYTQDPLDYDENEEEIEYPPSEPAEASNGYSSVDVSLRAPDSDLASPVESSPLDPHTKERRPQGEASDLKGQVESSEQPGTPAPPETEGESPAAPPPSPEGGAGPADQDALPAHPGGEAALPNYPPHLGHRRQVVGVEDDISSNTEVFTYNAANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDVDLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFYPGEERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYADSAVTSTSTRTYSLMSGAINQTRSYRIHQNITYQCRHAPITQQLNVDRVFALYSEEKVLRFAVTNQIGPVEQPTPVSPCYDGSHTCATTARCHPATGVAYTCECASGYQGCVDVDECATGFHRCGPNSVCVNLLGSYRCECRSGYEFADDRHTCILITPPPDPCEDGRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTENRCHPSATCSNTPGSFSCRCQPGYYGDGFQ---------------------------------------------------EPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDGLGHFTPLQHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTIRPTPRPDVTPFLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPETVINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQNNLNYPFNIVSYADHFYHTDWRRDGVIAVNRDTSQRSHLYGITAVYPYCP-G >KAB0344697.1 hypothetical protein FD754_021623 [Muntiacus muntjak] GDPAAGRPA--LLLLLLLSRAAALHSELFPYRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLYRQDTSPAVLGLAASYVRAGFPLSVHFTPTHAFLATWEQVGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGPYFSLTSTEQSVKNLYHSNLGIPGVWAFHIGSPLDNIRPATVGGDLSKARPSAPLGQSFSHAVALEGDYTQDPLDYDEIEEEIEYPPSEPAEASNGHSSVDVSLRAPDSDLASPVESSPLDPHTKERRPQGEASDLKGRVESSEQPGTPTPAETEGDLPAAPPPSPEGGAGPVDQDALPAHPGGEAALPNYPPHLGHRRQVVGVEDDISSNTEVFTYNAANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDVDLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFYPGEERARITQTAEGLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYADSAVTSTSTRTYSLMSGAINQTRSYRIHQNITYQCRHAPITQQLNVDRVFALYSEEKVLRFAVTNQIGPVE-----------------------------------------DVNECATGFHRCGPNSVCVNLLGSYRCECRSGYEFADDRHTCILITPPPDPCEDGRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTENRCHPSATCSNTPGSFSCRCQPGYYGDGFQ---------------------------------------------------EPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDGLGHFTPLQHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTFRPTPRPDVTPFLLYAQGQQIGHLPLNGTRLQKDVAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPETVINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQNNLNYPFNIVSYADHFYHTDWRRDGVIAVNRDTGQRSHLYGITAVYPYCP-G >KAB0375038.1 hypothetical protein FD755_013530 [Muntiacus reevesi] GDPAAGRPALLLLLLLLLSRAAALHSELFPYRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLYRQDTSPAVLGLAASYVRAGFPLSAHFTPTHAFLATWEQVGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGPYFSLTSTEQSVKNLYHSNLGIPGVWAFHIGSSLDNVRPATVGGDLSKARPLAPLGQSFSHAVALEGDYTQDPLDYDEIEEEIEYPPSEPAEASNGHSSVDVSLRAPDSDLASPVESSRLDPHTKERRPQGEASDLKGRVESSEQPGTPTPPETEGDLPAALPPSPEGGAGPADQDALPAHPGGEAALPNYPPHLGHRRQVVGVEDDISSNTEVFTYNAANKETCEHNHERCSRHAFCTDYATGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDVDLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFYPGEERARITQTAEGLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYTDSAVTSTSTRTYSLMSGAINQTRSYRIHQNITYQCRHAPITQQLNVDRVFALYSEEKVLRFAVTNQIGPVE------------------------------------------------------------------------------------VITPPPDPCEDGRHNCAPASQAQCIHHGDGSFSCACLPGYAGDGHRCTENRCHPSATCSNTPGSFSCRCQPGYYGDGFQ---------------------------------------------------EPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCDGLGHFTPLQHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTFRPTPRPDVTPFLLYAQGQQIGHLPLNGTRLQKDVAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPETVINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQNNLNYPFNIVSYADHFYHTDWRRDGVIAVNRDTGQRSHLYGITAVYPYCP-G >XP_020724590.1 nidogen-2-like [Odocoileus virginianus texanus] GDPAAGRPALLLMLLLLLSRAAALHSELFPYRGDQLLQEGDDESSAAVKLTLSLRFYDAQFSDLYVGTNGIISTQDFPRETQYVDDDFPTDFPAIAPFLADIDTSGGRGRVLYRQDTSPEVLGLAASYVRAGFPLSAHFTPTHAFLATWEQVGAYEEAKRGAPPSGELNTFQAVLASDESDTYALFLYPANGLQFFGTRPKESYNVQLQLPARVGFCRGEVDDLNRQGPYFSLTSTEQSVKNLYHSNLGIPGVWAFHIGSPLDNVRPATIGGDLSKARPSAPLGQSFSHAVALEDDYTQDPLDYDENEEEIEYPPSEPAEASNGHSSVDVSLRAPDSDLASPVESSPLDPHTKERRPQGEASDLKGRVESSEQPGTPAPPETEGDSPAAPPPSPEGGAGPADQDALPAHPGGEAALPNYPPHLGHRRQVVGVEDDISSNTEVFTYNAANKETCEHNHERCSRHAFCTDYAAGFCCHCQSRFYGNGKHCLPEGAPHRVNGKVSGHLLVGHTPVHFTDVDLHAYVVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPGWENGFSLTGATFIHDVEVTFYPGEERVRITQTAEGLDPENYLSIKTNIQGQVPYIPANFSAHMAPYKELYHYADSAVTSTSTRTYSLMSGATNQTRSYRIHQNITYQCRHAPITQQLNVDRVFALYSEEKVLRFAVTNQIGPVE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DKV--------------------------------------------VSMSKI-------------------------------------------------------------------------------------------------------- >XP_018084587.1 nidogen 2 L homeolog isoform X1 [Xenopus laevis] GTAATARSKLLLPLHCLLAFSAAISRELFPYKGDVLLQEGDDETSEVVKLSQPLLFYEAQFSNLYVGTNGIISTQDFPRETQYVDDGFPTDFPVIAPFLSDIDTSNGKGKIFYRQDNSEPVLNHAAREIQRGFPE-ATFIPNHAFLVTWENVGTYEEVTRHSASSDRRNTFQAVLAYDHSDAYAIFLYPEDGLQFFGTRPKESYNVHIELPARVGFSRSEA------GPYYSVTSNEQSVKNLYTGNVGVPGIWVFHIGSELDNVIPAKFFGAPANEQSLENSHTSFPEHRLFENHENEDSIFYEESEDEPTHETHQEGDNTGNQGYLDIDDQAEDEQKATSS--TPYTPSESE------TDRDGPLQEPQIQTGE---NLDLTREDTDLPSHNAP---PSNSEDLPIYPESAVLVGSHPNNFERG---RQTDADPGLQTDVFSFKPAGKETCERNHGRCSRFAFCADYSTGFCCHCQEDYYGNGVHCLPRGAPHRVNGKVSGNILVGQTPVNFIDADLHAYIVANDGRAYTAISNVPDPASWSLTPLAPIGGLFGWLFALEKPGFQNGFSFTGAKFVHNIDVTFYPGEEAIHITQTANGFDSEGYMNVKTAIQGKIPYIPETSTIKLSPYTELYQYSGSVVTSTAYREYTVLSSNEEQKLSYRLRQNVTYQCSHSQSAQKLYVDRVFALYNEEKVLRYAITNYIGSVHEDLKVNPCYDGTHLCDTRAKCQPGSGLEYICVCASGYQGCTDVNECEVGFTRCGQNTVCVNLQGSYRCECASGFTLSGDEHNCILA-SSINPCEDGRHMCN-RDTSRCVPHGDGVYTCQCFPGFIMSGEKCVEHRCHPDASCTNTLGSFSCRCNSGYEGDGFQLRTPCLFVPECDEGNYVPLQCHGSTGHCWCVDKEVAGTRTPPGRPSPNCGDEPTQRPQTVCERWKQSLIEHYGGKPSGEHYVPQCDQYGDFSPLQHGNSGYCWCVDKEGREIEGSRTEPGMTPACIPTVAPPTMHPTPRPDVTPFLLYAQGQQIGYLPLNGTRLHKDKARTLLSLHGSIVVGIDYDCHEKMVYWTDVAGRTINRASLEPGAEAEIIINTGLMSTEGLAIDYLRRTLFWTDSGLDKIESSRLDGTERKILFDTQLVNPRAITVDAVRGNLYWTDWNREAPKIESSFVDGSNRRILVNDNIGLPNGLTFDPFSKQVCWADAGTKKLECILSDGTGRRVIQSNLNYPFSVVAYANHFYHTDWRRDGVISIKKDTGQRSHLYGITAVYPYCPSG >OWK09497.1 NID2 [Cervus elaphus hippelaphus] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVPP---------------------------------------------------------------------------------------------------------------------------------------------QL----------------VAIRRQVWPTP---------------------------------------HLDVDECATGFHRCGPNSVCVNLLGSYRCECRSGYEFADDRHTCILITPPPDPCEDGRHNCAPASQARCIHHGDGSFSCACLPGYAGDGHRCTENRCHPSATCSNTPGSFSCRCQPGYYGDGFQ---------------------------------------------------EPTQRPRTVCERWRESLLEHYGGTPRDDQYVPQCEGLGHFTPLQHGKSDFCWCVDQDGREVQGTRSQPGITPACIPTVAPPTIRPTPRPDVTPFLLYAQGQQIGHLPLNGTRLQKDMAKTLLSLHGSIVVGIDYDCRERMVYWTDVAGRTISRASLEPGAEPETVINSGLISPEGLAIDHFRRTMYWTDSGLDKIERARLDGSERRALFHTDLVNPRAIAVDPIQGNLYWTDWNREAPKIEMSSLDGENRRILVNKDIGLPNGLTFDPFSKLLCWADAGTKKLECILPDGTGRRVIQNNLNYPFNIVSYADHFYHTDWRRDGVIAVNRDTSQRSHLYGITAVYPYCP-G >XP_791550.3 nidogen-1 [Strongylocentrotus purpuratus] ---------LLGIFAVLIAVVNCLPDQFFPFTTDKKLNRRSKK-PLTLSFREPFTFLGEEQSLLYIVRDGYVSFSSGARG------------SKIAPFHTKLKLIRGQSSVWYRTTVSSNEEDEIINLIQRNFRSRTTFSPSSFVIVTWENMAVRNS----DHEVIGTVTFQLILVADAMHSFAFFLYDENN--------DYPRPDRIGSNIDAGFTSGKAHNQWEFEMVYTTENKAATLFEAMDSNVGMNGMWAYKIDGMDGNIIPA------------------------------------------VAYVPVESLP-------------------------PPQD-------------------------------------------------------------------------------AVNIQLDNTFDVVL-----DFENQCT--RETCSVDGRCVPYPTGHCCACNEGFMGNGIHCLSINDNGRMNGRVNGTINGVTIP---DEVYLHTFIMGGGGRTFTAISPVPSSIAYSMQILLPIGELMGWMFAEPAAKGINGFMQTGGDLLYSANIRFENGDE-VSIIQRYTGVDESGVIGGYVTIDGNVPNLSPGTSVSVDRHSEVYTKYPGYVYSSEQRSL----DADGQTIRFSIEQTITYQCEADDTAMRMNTTYAYSIFEQGDILRYAMITNVGPDI----TDACQDNN--CGTNAECFPQAN-TFTCRCRAGYTGCTESPSDPCDNNDCDRNANCYPAGNSYTCQCNTGFN--GDGRVCVAD-QASDPCDTND--CS--LYAYCYPTNDGSFYCQCATGFTGDGRNCENNNCSPYAYCPRGDTDFTCECAPGYVGDGYNDGYLCELVNLCS-----------------------------------------------------------------------DCGRDADCLP--EGRGYRCICRAGNGDGLTCEDVDECLEGACQNNRGSYTCRCNAGCEALPSLVFGQGMSVMNLPRDGSA-----GNKVYMKSRQTVVGLGYDCRHEYVYWTDISGRAIMKASLD-GRDVSVVVNTSLSSPEGVAVDHLSRNLYWTDSGFDRIEVANLDGTNRHVLFDTDLVNPRAIVIDPVGGYLYWVDWDRSYPRIEVSGMDGSGRAVFLDEDLIMPNGLTIDLVSQLLCWADAGTQKVECMNLDGLSRYPVYRPAQYPFGLASLGNNLYWTDWQTSNIQFINKNGGGNGRTYGIAAVTQ-CTDG >XP_038046990.1 fibropellin-1-like isoform X23 [Patiria miniata] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AWLFALPSGKGYNGFMLTGGKFRQTLNITFSTGEQ-MLITQDFQGVDENGYIRVIADWNGNIPEITPSDYVFVDDHKEEYVRHLGVIHTFAKRSLQV----NDDTISYTMDQTIEYDCSADENFMRVSMTETYLIYESEEILRFSMIGKVTPAS----DDPCVSNN--CDRNAQCLPAGDSGFRCKCNEGYEGCTGSNPCA--QNSCDVNGYCIPQADRYTCACNAGYQ--GDGYTCSVDCQVSNPCDNNA--CD--ANAYCVPTQSG-YQCYCNDGYSGDGYNCQNNNCDPNARCVSAVFGYQCFCDPGYRGDGYTDGLTCEQIDRCANACDVNAYCVSTASNCYCNDGGFVCREIVDPCANNNCDVVPSQSGQCYCN-------QGFNGDSVDLCYNNRCDFNAECSPAQEGRGFRCVCRSGQGNGLVCEDIDECSQSGCYNVRGSFSCYCQPGCQEVTALIYARGMAVMRVPLNANK----PGNKIVFRSGQTIVGLGYDCQEEYIYWTDVSGRTISRAKAD-GSSTEVLISRGLSSPEGVAVDWLSRNMYWTDSGYDRIEVANLDGSNRRVLLKTDMINPRAIAVDPIGGLMYWTDWNRDAPKIERANMDGSERSVLVDSNLGLPNGLSLDYTTSQICWTDAGTKRIECMNMNGLTRFTVLPNSNYPFSIASYGFKLYWSDWETKSIQTISKTGGGNGRIYSVTAITS-CPST >XP_026296012.1 LOW QUALITY PROTEIN: nidogen-2 [Apis mellifera] GTGRESRETLVLATLVIAPFAVALNNDLYPYPGTSILQTDPNGLSAETILKTPIAFYDQIFNSIFVNGNGVLSFARAM--HRFFNIAFPLDDPVIAPLYTHVDTRGS-GRVYYGETDAPEILARAGGMVRSAFTDAADFVPTHAFLATWVDVGYYNG------KSDKVNTYQVAISSNGTHSYVELLYPDDGIQWI-----QGESHPNGAKAQAGLMS--------EGRMYTLRSGTDQIQNVDWSNVNRPGQWVFQVGPDEEDIK----------------------------------------------------------------------------------------------------------------------------------------------------------------------VPDNVEDSSA----TNEVANCRTGATACHSKATCVDYEVGFCCHCKQGFFGNGKSCQPNDVPLRVNGRISGTINGVE----FLARDLQCYVQTKDGRTYTALSRVPEEIGASFQLLGNLGGVIGWLFAKPIGETKNGYELTGGLFNHTAELTFPSTGDKVTIRSNYLGLDVFGQLKMQAQIEGTLPQLGRDTGLDYGDYDELYTRVTGVIRSRAERVCKLAEGVESRELDFVQDETIYYNCPYLTDTTRLKFFRGVTTYETEGIIRFAVNTKVAPLE----EDPCIQGRETCGDHSYCVVDGD-SFKCVCNPGYQYCIDVNECTAGKHMCSPDAQCINQEGSHTCQCRPGFS--GDGRTCDKLATQRAPCDVED-NCS--PNGFCNIDAEKKYVCVCLPGFIGDGYTCYMNRCHPYAQCVTSTADYECRCNQGYEGDGMEDGTMCSVDSRCVDCSTNPSQCHVNAQRCVCAEGGIRQCVED----------------HIGCN------------------VLNNCGRNAVCGYNQTSANFVCVCQQGYGDGFTCLPQSSCRHDPCVAAGNQYACVCNEGCKSRPFLLVNQGMATLRIPFAPTY--EDPGSPIYIAYMQMAIAIDIDCMNGKAYSSDISGNRIIELTYN-GSMAETFLP-KVSNPEGLAIDWVSRNIFWT--GKTTVEVANLETKKRKVLVSDGLVNPRGIAVHPYRGKIFWSDWNRASPKLEWANEDGTDRAIFLQDYVKLPNSLSIDWAMDELCWADAGTFTISCMEIDSRKINVVANQLTYPFGLAISQQHYYWTDWKTHKIEVAMKSTGGSGKLYGIVVVPESCPRV >XP_039259166.1 nidogen-like [Styela clava] ---------AVLLAVFAVGQSAVF-NDFYPFENDHRVPKGDNTSSPQFELDLPIIFYDSVYNGIKVNADGFVTLGVVEHEEEHLLE------PVLVPFGFNLNNTDA-SEIYYQEHKDEATLSRATNDIQKAFVETEAFVAKSAFIVTWVRLESPEH-------PGLTFTFQCVVVSNHLSSFAIFLYADDELA-----AGQSEEIRNQLIAKAGFSDKGGDQL-----------ESMTATELLGGNAWSTGEWIFQIGGEEEEIP--------------------------------------------SHHLKAEPIH-------------------------SGFE-----------------------------------------------------------------------------------VPEVNFNEDY----GSDQQDCD--SLECDPESTCTAFADGYCCQCSEGSFGNGYACIREDDDVRYNGQVDGYSIVMSDPWSAKGVDMHSYVVTKDGRAFSVMNEISAKLYRALQPMAIFGTTLGWLFAQAEAPAINGFQYSGGKIVSETYIRYTTGQYEFRIRQEYDQVINDKVLNGRMTFSGRLPPVEEGENINVDDYTQIYKRTADSIRSRDTRRYIV----GDTEHIFTVDQSIRFECEASFADLAVDVSEVFLKFFDENNLRFAVNSRIRPAESIIPDTPVPDTP---------------------------VPDTPE-----------------------------------------TPSETPVEKPE-----------------------------------QTVCERQ---LQQVQQFQ-RENPGIVDEIFFAQTPCQFMPRCMSGAYEPVQQLPDGS-FMCVDFEISRSTEMP-----NC--TPCQLAAYVAESSNIFL--------ETNEFVVRCKADGDYNPEQ--VETYCYCVDENGLEITNSRVETTFGEDCGKFNSKPVTSTVTTPTTTTRLLFAQTMGINVIDLPVTR-ENSVSRRLFARSDQITIALGYDCSSKKYYWTDVSKRRIYSSVLDGDGSRAQFLGDRLRSPEGISVDFLSGNVYWTDSEYDRIEVASADGSNRMTVVSGDIVNPRGIAVDPIRGRMYWTDWNRKAPKVWVANMDGSDRRVLLSEGLGLPNDITIDFYRQRVCFVDAGTFKVECMSLNGEGRETIYQPRPHPFGLAVDGDVLYYSSWGGSKVHAVNWRTGAHGQMYGVEIAHSQCPRG >NP_001256467.1 NIDogen (basement membrane protein) [Caenorhabditis elegans] ---------MLILLFLYLLIETTTAPAFYPYAGDNRLDYSMEQ--SAIALKIPLTYMEQSVDELFLSHNGIVGLGKPT--PEKIGGLMTISTPAIAVFYVPVTS----GVIDYRSSDDQGLLTKLTQDVKQVFADAVEFHGLQAVIITWTQIENAEK--------DGPASFQLAIVSDGISTYAIFRYES-----------LPWSSSMGYYAQAGFVRSI-------GKIQTNVSGGPDVKELVLSNNQFGNFFIFRVSGIEDPKDEGAD--------------------------------DYDYNNYDQEYEGEHPAD-----CPKDKFVDRTVRDER-----APQEPRPELENTVED-------------------DE-DDEQVDEEP------ARQAQEQHHQQHHQ---------------------PDQPQQQPQRSQEGSLPKMSCSRDDKSCHANSVCQDFEGGFCCNCDTGFYGNGKECLPKGEPQRISGSFEGVIN--RIPI--DKTELHTFATSTDGNVHTAVSKIPSDLGHPLRFLYSIGGVMGWLFADVQSPNYNGFQLTGGLFNRTVALHIEQNYY-VTIKQEFSGRNIHDYFKSHLFVSGTLPDIAPGSEVIFPDYEEEYVRERGYLTSKAAFDVIVRDGGNVQTYRMSVDQQITFECPNKEHSMKLHVKRINVVYNDEGVVRYGAKNSVGPAVSISTDSVCAPGRHQCTPNMKCRVVDP-SYRCECEPGYQACQDLDECQRGDHNCDQHAKCTNRPGSFSCQCLQGYQ--GDGRSCIRE-NQQTPQEM-------------------AGVGATTEGF--------HNQCHQWGECTSEHPTGRCKCRGWYVGDGVNNGVTCERHEQQQTGS--------------------------------------------VCR------------------SHDECSEHGSCAYHHSLGYYQCACTEPVGNGVE-----------CTLPGSSASAESSTR-----KLLVARGMAIFERSTNPDE----YGKQLIVIPHHIPVGIDFDCKEEKIVWSDMSGHSIRTSSLN-GTEHKSYFNKELSSPEGIAVDWSSRNVYYADSMNDEIGVASLNGKFKKSLVTEGLVNPRSVVLDLYGRHLYYSDWHRENPYIGRVDMDGKNNRVFLNEDVHLPNGLTILPNRRELCWVDAGNHRLSCIQYNGAGRRTVFSSLQYPFGLTHEEQKFYWTDWKDNRIHSVGVYGEGSGKVFGILAVPKSCVGP >NP_610575.1 Nidogen/entactin, isoform A [Drosophila melanogaster] ---------VILVSGQFEHYLDSLRSELYEFGSIHLLPKGDSE-TIVLQLEQPIHFYGEQYEQLYINTNGILTFNSEF--PEYLNQPFPLEYASIAAFYSNVDTSFSGTSISLFESKEQSILDRASSLVRYAFSSQSEFEARQVIVATWRNVGYFDS------KTDRLNTFQVALIANEQSTFVQFIYPDGGLNWL-----QGETAGLGIRAQAGFVAED-------GRFYTLNSGSENARFLSSTNLGVPGVWLFEVAPNEQNVR----------------------------------------------------------------------------------------------------------------------------------------------------------------------SPD---NAESLTESPALALSCQAHAHQCHEKAECHDKAEGYCCVCGSGFYGNGKSCLANDQPIRVTGTLTGELN--KQPVS-EEAKLQSYVVTSEGRTYTTINPLTPELGAQLRLVLPLLTTVPWLFAKSVGGVANGYQLTGGVYTHVSRLQFDSGEN-LHVNQTFEGLNYWDQLSVKIEIYGEVPAVAADAVLILPDYVEEYTFEPGELKSVQVLNINITE--EQRVLGLQVEQRILYRCLRDDSATKVKISKVALDYVRDQALRIGAMSKVGVTP----SNACNDGTADCVENSVCVPYED-TYRCDCYHGFAACLDIDECATGSHVCDENAVCDNTEGGFNCYCTEGFE--GNGYRCLSNQPNPYPYPEEQIPQHPDECYRCSKDADCQGRCTCHEGFDGDGYTCTDENCHINATCYGQELRHICTCQPGFRGDGYNNGFNCQVSDRCVAGRCGSVFCGSNAIYCDCLDGALTGCTSKP----------------LSCH------------------VLNNCGIHATCEPTEDPANYECQCIAGKGDGYVCIEEQNCLNNPCRSTNSGLVCVCNQGCQERQFLIVSQGVMIARVPLNGRNVRP-------ISVAQMAIGLDKDCVEGRVYWGDISTKKIVSTKYD-GTDLRPFITTDIESPEGIAIDVISRRLYWADSAKDTIEVASLDDSLRAVIINKQLVNPRGIAVDPYREKLFWSDWDRESPKIEMSNLDGTGRELLLGDDVTLPNSLVVLENSGEVCYADAGTKKVECIEPQNRQIRTISNELSYPFGITFTHDQFYWTDWTTKKVEIVDSLGAGSHKMYGMTVVEQHCPQY >XP_031557799.1 nidogen-like [Actinia tenebrosa] ---------LVFLLVLLVIQSSCLVQEFYPDGSSELLARR---ISPPVTLGTTYNLYGKPYTSLRVYKNGLITLGEEPISQKHRKFLFPPEAKVIAPFYGQGDFTNT-SRISYGETRDSDILTRASKDVKQSFSGEDEFNASAVFIVTWCQVKHAQH-----SQHKKNNTFQAVLVTNGDQTFVIFNYLTRGLQWA-----KGYHSQWKAYAQVGFSAGD------FVRYSTLPSGTNQVHWLAKSNMNTPGRWIYKVGWMHGNEVQSADSFE---------IDDSTNT------DFFAAQF-YDGCFVVHGYLTANRSQ-----IWKDVSIRFERRQKYAAL--TNTDQDCDMACSVND-------------------DEVCGGQMTQ-----------------------------------------SVLAAVQSDQSGGQRKRKDVDECAVGVVSCHANATCINKSPGYCCQCNEGFYGNGITCIEIGAVQRMVGFLSGTVNGEE----FISLNMDTIAFSDDGRAYVSVRAFPPYLAHSARVLTPLTDVVGWMYAKPKPSGYNGYNVVGARFVRRASLRFDSGEE-LAILQKYQGRDVLHYMKVETTMNGAIPRIHPKAEVRMRKFRQEFQRTAGRVQSRGTVKYQV----DGREHYFTVDQFIDYDCGQHVEADVL-----TSNYDAQAFLGIAVKGFINTTLSQEADKMCGSKKVTCHTRGVCIQYRG-DKECRCNHGYLGCDDADECKLGRYRCAPDADCVNTVGSYRCVCKKGYV--GDGKTCQKDTALEGRCGGVV--CS--TNAQCV-----QSKCVCNPGFQGNGKNCSTHRCDTNADCINTVGSYSCRCRLGYQGDGLSNGQACNDGQFCEDGTCGGVQCHPDASRCVCKPGEHATCTNSAGSYKCSCNLSPTDGNTCVCN-------DGFSGNDECDLGHAKCHRKAECVNQVRGIDKTCKCKDGSGDGVICTDVDECIKDPCVNAFGTYVCQCKPGCEKICSLIYTKGNSVQRMSLPPRS---NAIGLVYNHEGMVNVGLDYDCVEEYIYWTEVMEGCIMRAKYD-GTNRELVFQSEVRSPEGLSVDWIGRNLYWTDSGLDVIEVSRLNGSNRKVLISNGLYDPRAILVDPPSGKMYWSDWTRRRPRIETADMDGTNRRVLVYDDLGLPNGLTLVQTTNELCYTDAGSWSIRCVDLAGLNVRKVLTRVTYPFGIAYFNRTLYWTDWNQNLIHRIGVESSKTGKIFDVKAVQP-CPAK
PhyML tree of selected proteins (NP_610575_1_Nidogen_entactin__isoform_A__Drosophila_melanogaster_:1.46974529,XP_026296012_1_LOW_QUALITY_PROTEIN__nidogen_2__Apis_mellifera_:1.14162392,(XP_031557799_1_nidogen_like__Actinia_tenebrosa_:1.82661293,(NP_001256467_1_NIDogen__basement_membrane_protein___Caenorhabditis_elegans_:1.9954361,((XP_039259166_1_nidogen_like__Styela_clava_:2.2868532,((tr_X1WE42_X1WE42_DANRE_Nidogen_2a__osteonidogen__OS_Danio_rerio_OX_7955_GN_nid2a_PE_1_SV_1:0.23040745,(XP_030265795_1_nidogen_2_isoform_X1__Sparus_aurata_:0.08209025,(XP_011482732_1_nidogen_2__Oryzias_latipes_:0.19892233,XP_015807982_1_PREDICTED__nidogen_2_isoform_X1__Nothobranchius_furzeri_:0.16043096):0.03926619):0.25202394):0.26875929,((((XP_014375969_1_nidogen_2__Alligator_sinensis_:0.03591132,KYO47226_1_nidogen_1__Alligator_mississippiensis_:0.00942927):0.22572113,(XP_013223751_1_nidogen_2_isoform_X1__Columba_livia_:0.18924295,(XP_010710486_1_nidogen_2__Meleagris_gallopavo_:0.05294926,XP_015132255_2_nidogen_2_isoform_X1__Gallus_gallus_:0.02953043):0.12298534):0.21338611):0.11370368,(((XP_020957573_1_nidogen_2_isoform_X1__Sus_scrofa_:0.07015739,((NP_001095535_1_nidogen_2_precursor__Bos_taurus_:0.01646176,(XP_017909832_1_PREDICTED__nidogen_2__Capra_hircus_:0.00839233,XP_004010577_3_nidogen_2__Ovis_aries_:0.00491381):0.01478479):0.00258045,(XP_020724590_1_nidogen_2_like__Odocoileus_virginianus_texanus_:0.01231798,((KAF4017381_1_hypothetical_protein_G4228_009148__Cervus_hanglu_yarkandensis_:0.00185551,(XP_043327612_1_nidogen_2__Cervus_canadensis_:0.000468,OWK09497_1_NID2__Cervus_elaphus_hippelaphus_:0.047929):0.00045935):0.00840871,(KAB0375038_1_hypothetical_protein_FD755_013530__Muntiacus_reevesi_:0.00694998,KAB0344697_1_hypothetical_protein_FD754_021623__Muntiacus_muntjak_:0.00387977):0.00682823):0.00122474):0.00665937):0.06451311):0.02975825,(XP_023111456_1_nidogen_2__Felis_catus_:0.07397018,XP_038443101_1_nidogen_2_isoform_X1__Canis_lupus_familiaris_:0.0676545):0.03086352):0.02161163,((XP_002824786_2_nidogen_2_isoform_X1__Pongo_abelii_:0.01486021,((XP_009426087_1_nidogen_2_isoform_X1__Pan_troglodytes_:0.00088375,XP_008955315_2_nidogen_2_isoform_X1__Pan_paniscus_:0.00177048):0.00307321,(sp_Q14112_NID2_HUMAN_Nidogen_2_OS_Homo_sapiens_OX_9606_GN_NID2_PE_1_SV_3:0.00495251,XP_030857550_1_nidogen_2_isoform_X1__Gorilla_gorilla_gorilla_:0.00581816):0.00087585):0.00388211):0.07950592,(XP_008267875_2_PREDICTED__LOW_QUALITY_PROTEIN__nidogen_2__Oryctolagus_cuniculus_:0.29813805,(NP_032721_2_nidogen_2_precursor__Mus_musculus_:0.03361346,NP_001012005_2_nidogen_2_precursor__Rattus_norvegicus_:0.03680477):0.11009561):0.02044126):0.01012458):0.17867123):0.13927444,(XP_040188888_1_nidogen_2__Rana_temporaria_:0.28749682,XP_018084587_1_nidogen_2_L_homeolog_isoform_X1__Xenopus_laevis_:0.21836458):0.207698):0.1783218):0.78914632):0.35220671,(CAE1293091_1_LRP5_6__Sepia_pharaonis_:3.29989531,(XP_791550_3_nidogen_1__Strongylocentrotus_purpuratus_:1.05853055,XP_038046990_1_fibropellin_1_like_isoform_X23__Patiria_miniata_:0.67325022):0.40289463):0.29315423):0.17967904):0.13385116):0.43785829);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)