PB0067

DATABASE

Click here to access PB0067 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0067	P00740	Coagulation factor IX	F9	F9 p22, FIX, HEMB, P19, PTC, THPH8	Homo_sapiens	Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ ions, phospholipids, and factor VIIIa.

Domains

Gene Ontology

PF00008 (EGF) PF00089 (Trypsin) PF00594 (Gla)

GO:0004175 (enables) endopeptidase activity GO:0004252 (enables) serine-type endopeptidase activity GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0008233 (enables) peptidase activity GO:0008236 (enables) serine-type peptidase activity GO:0016787 (enables) hydrolase activity GO:0046872 (enables) metal ion binding GO:0006508 (involved in) proteolysis GO:0007596 (involved in) blood coagulation GO:0007599 (involved in) hemostasis GO:0031638 (involved in) zymogen activation GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005788 (located in) endoplasmic reticulum lumen GO:0005796 (located in) Golgi lumen GO:0005886 (located in) plasma membrane GO:0070062 (located in) extracellular exosome GO:0062023 (part of) collagen-containing extracellular matrix

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P00740|FA9_HUMAN Coagulation factor IX OS=Homo sapiens OX=9606 GN=F9 PE=1 SV=2 MQRVNMIMAESPGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGNL ERECMEEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCP FGFEGKNCELDVTCNIKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGR VSVSQTSKLTRAETVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPW QVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRII PHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVF HKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVE GTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >tr|E7F301|E7F301_DANRE Christmas factor OS=Danio rerio OX=7955 GN=f9a PE=4 SV=2 MASFILVLFPFLLLQAALGSVFLDGEKADSVLWRRRRANTWLFEEFLPGNVERECIEEKC VLEEAREAFENDEKTMEFWASYVDGNQCKPSPCQNQGTCEDQMGTYSCNCLPGFVGKNCE IVTAKKCDVDNGGCEHFCVLLESHKTQCQCAYGYKLSEDGLTCEPIVKFPCGKTSKPAVK TYGTASVTNTTAQFSNMTVKSTSSIPKPDNLTNPTNSKDIKEKLAPPRAKLPKWAFEEYL TSPAPTVSGPKSRIIGGNSALPGEIPWQVALVSRSTQQVFCGGSILNPLWVITAAHCLLG NHNGSFYIRVGEHDVSKIEGTEQNVDVIKLISHPRYNSKVSLFNHDIALLRLRSPIRLTP TVRPICLGPMVFSNTLLQSGTLATVSGWGRVRFQGRSAATLQKIELPYVDRTVCKESSSD PITHFMFCAGHSDSPKDACQGDSGGPHVMRYHNTWFLTGIISWGEECAKKGKYGVYTQVG NYYRWIQHTMGVTTGALLTNVDQ >tr|Q1RLV2|Q1RLV2_DANRE Christmas factor OS=Danio rerio OX=7955 GN=f9b PE=2 SV=1 MVKIYPVILMCSLLLEFWLSSGASVFLPRDLAESLLKRQKRYNTGGLEEMMKDNLERECY EERCSLEEAREVFENNEKTMKFWITYMDGDQCLSSPCQNGGKCEDGMNTYTCWCPARFSG KNCELEMAKQCHVNNGGCMHFCIVDKIYGAVCDCAEGYRLAVDGRSCEPRGQYPCGRLGK IIAQTLNSRALESTETVNQNQTISHINGTEYNTTESSPTDLSEMNSTSTPRNSLQNVSSS PILTNINNTTNNKYRIVGGDEAIPGEIPWQVVFLEKVNKIVFCGGSLLSEEWVITAAHCV EGKQGSFFIRVGEHDVSKMEGTESDHGIEEYHIHPRYNSQRSLYNHDIALLKLKKPVILF DYAVPICLGSKDFTENLLQSAENSLVSGWGRLRYGGIESNVLQKVELPYVDRIKCKGSST DSISRFMFCAGYSTVRKDACQGDSGGPHATRYKDTWFLTGIVSWGEECAKEGKYGIYTRI SKYMAWITNITRIRTGHMSNGDQQSLN
Selected proteins from model organisms >sp|P00740|FA9_HUMAN Coagulation factor IX OS=Homo sapiens OX=9606 GN=F9 PE=1 SV=2 MQRVNMIMAESPGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGNL ERECMEEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCP FGFEGKNCELDVTCNIKNGRCEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGR VSVSQTSKLTRAETVFPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPW QVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEETEHTEQKRNVIRII PHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVF HKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVE GTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >tr|E7F301|E7F301_DANRE Christmas factor OS=Danio rerio OX=7955 GN=f9a PE=4 SV=2 MASFILVLFPFLLLQAALGSVFLDGEKADSVLWRRRRANTWLFEEFLPGNVERECIEEKC VLEEAREAFENDEKTMEFWASYVDGNQCKPSPCQNQGTCEDQMGTYSCNCLPGFVGKNCE IVTAKKCDVDNGGCEHFCVLLESHKTQCQCAYGYKLSEDGLTCEPIVKFPCGKTSKPAVK TYGTASVTNTTAQFSNMTVKSTSSIPKPDNLTNPTNSKDIKEKLAPPRAKLPKWAFEEYL TSPAPTVSGPKSRIIGGNSALPGEIPWQVALVSRSTQQVFCGGSILNPLWVITAAHCLLG NHNGSFYIRVGEHDVSKIEGTEQNVDVIKLISHPRYNSKVSLFNHDIALLRLRSPIRLTP TVRPICLGPMVFSNTLLQSGTLATVSGWGRVRFQGRSAATLQKIELPYVDRTVCKESSSD PITHFMFCAGHSDSPKDACQGDSGGPHVMRYHNTWFLTGIISWGEECAKKGKYGVYTQVG NYYRWIQHTMGVTTGALLTNVDQ >sp|P00741|FA9_BOVIN Coagulation factor IX OS=Bos taurus OX=9913 GN=F9 PE=1 SV=2 MWCLNMIMAESPGLVTICLLGYLLSAECTVFLDRENATKILHRPKRYNSGKLEEFVRGNL ERECKEEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGMCKDDINSYECWCQ AGFEGTNCELDATCSIKNGRCKQFCKRDTDNKVVCSCTDGYRLAEDQKSCEPAVPFPCGR VSVSHISKKLTRAETIFSNTNYENSSEAEIIWDNVTQSNQSFDEFSRVVGGEDAERGQFP WQVLLHGEIAAFCGGSIVNEKWVVTAAHCIKPGVKITVVAGEHNTEKPEPTEQKRNVIRA IPYHSYNASINKYSHDIALLELDEPLELNSYVTPICIADRDYTNIFLKFGYGYVSGWGKV FNRGRSASILQYLKVPLVDRATCLRSTKFSIYSHMFCAGYHEGGKDSCQGDSGGPHVTEV EGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >XP_031561359.1 atrial natriuretic peptide-converting enzyme-like isoform X3 [Actinia tenebrosa] MSKLQSMMCKLFVVCSLLAVCLQTTVSLECSYSLGVEKYIIPDSSLTASSEIDYWQGAAQARLNLVPYYTWYPSGWTPGA NDGHPWLQIYLKHPYVVTGIATQGRGSLNVVQDWVRSYNLSYSMDGKTWKFCRSNVGSIKVFPGNTDANTVRKNTISPPF TATYVRINPLTWSGQPSLRVELYGCLDSRYCGAKLGMQNGSIPDKHITSSTQLSALYAASQGRLNNVPSALSGGCWRTGD MDYSPWLAVNLXKIFKVMAIGTQGNPVADEWVTYYYVRFGHDGIHWNYIYDADMIKYYIGNEDRNTKTQNVLDQPIISQY IRIDPILWNGERVALRVEFFGCMSVNKCFLSLGMEDRRIPDASLSASSALSNTNSPTYSRLHNQVAFQSLTGWSPSTTDQ NPWLQISLGQLAIVAGVGIQGGSVQNWWETGKWVTSYKVGYSKDGITWMTYSVNGVDKIFPGNTDSTSVVTNTFPTPIKA LKIRIYPKTWNGGAYLRMELYGCRENQSVAVDHCDSNPCKNNATCVDHVANYTCTCASGFTGRNCGTDIDDCNPNPCRNG ATCTDLVNGYICACRTGFTGQNCETDIDDCQSSPCRNYATCTDLVNNYTCACASGFTGRNCEIDINECQSTPCKNQATCI DQVNNYTCACANGFSGRNCEIDIDDCENFPCENNATCIDHVYNYTCSCVSGFTGRNCEINFDECQSTPCQNNATCIDHVN SYTCSCASGFTGSNCETDIDDCLPKPCENNATCTDLVNNYTCACASGFTGRNCEIDVNECQSEPCLNNATCTDHVNNYTC SCASGFTGERCETDIDECQSSPCQNNGTCIDEVNGYICSCTSKYIGEQCEEVKTHCSSNPCMNGGICVNKPTTYWCQCLY GYDGNQCEIVLNPNKECGRRVQARIVGGESAFPGSWPWQVGLLAKEDKKHYCGGTLISKEWIVTAGHCVLFREPDEILVV LGEYDLSVAEGNEVIKNVSTIISHPLYRWWTSDYDIALIKITEPLKMYNRFIYPICLPLNTELPPAGTQFTITGFGKLAH GGAAAKRLQQAIVPLISHDLCKKTYEGKAIITDRMMCAGHAEGGIDSCQGDSGGPFIKEKSNYCWYLYGVISWGIGCANP NSYGVYTNVLIARSWIKNQTNV >XP_016769420.1 trypsin-1 [Apis mellifera] MCIRTTICLAVIVAVVACTVNCEEVQSSVIKEGINLNATQYNATINDDKNFWDWILAGILSPSDSTTENPKPGTPEECLP CKCGLTNVQRRIVGGVETQVNQYPWMVLLMYRGRFYCGGSVISSFYVVTAAHCVDRFDPKLISVRILEHDRNSTTEAKTQ EFRVDKVIKHSGYSTYNYNNDIALIKLKDAIRFEGKMRPVCLPERAKTFAGLNGTVTGWGATAESGAISQTLQEVTVPIL SNADCRASKYPSQRITDNMLCAGYKEGSKDSCQGDSGGPLHVVNVDTYQIVGIVSWGEGCARPGYPGVYTRVNRYLSWIS RNTEDSCYC >XP_038051917.1 trypsin-like [Patiria miniata] MLKFLVLCALAASVYADCGVQVISPSLSKIVGGDEAVPGSWPWQVMLRKKYWGGDYQFCGGTLINDQWVVTAAHCFYNYG NINLYSAVVGAHDRDAVDATQSSVGLAQVFLHEDYNTRTLDNDITLLKLSSPVSLSDYVTPACLPQREVATGTDCVVTGW GDQETTVDDPALQQVVVPIISTAQCNKATWYGGDITDNMICAGYSQGGKDSCQGDSGGPFVCAASSGAYELVGVVSWGYG CADARNPGVYAKVLNYVDWINNIVANN >XP_039268100.1 A disintegrin and metalloproteinase with thrombospondin motifs adt-1-like [Styela clava] MQIRLTILLLCLTLMKARAEEEECKDKVSYCKRMKSFCDHATYKQYMLDNCIATCKKCRKDIDPDGLCLKDNGGCEHTCD VEDKTIKKCSCFSGYTLKKDGLTCTDVDECTIKGICLRGKHCTNVEGGFFCDEAKCTNPEKPYLGRPDCCTKEPDTAECG VTARGVERIVGGNDSFLGQWPWQVYINIDTSIICGGTLINRNWVVTAGHCFKGFSSETKMELFFGVLELSKLKQGHVQKR NMKKHILYPNWNEDKFEINDIALIELDKPVRFNRWVRPVCLPNGEKPKIGTKCYAAGWGLQHEDDLSPATKLQHVDLPIV EPQKCIKAYKDEDTKVNRTIMMCAGYDEGGKDSCRGDSGGPFVCQRCNSCGWYLAGVVSFGSGCAQKGFYGVYADVHYFE KWISEMTKIPVNNAKSCTGPYMETWSKWSTCTVTCGIGGKHTRTRQCLHKGKVSDQCNGPLKQTDDCPRIRCPRFGRFSD WSKCTKTCGGGLRTRIRECLHGKIGQDGCPADDAVENEDCNKQTCPVWEDWSEWKTCTKTCGTGVEARTRKCIGGKPSDE GCDGKATEERKCNEELCPGWSDWGPFGRCSKTCGGGTQVSERQCIGKKCPGEDNKSQVCNKQLCPVFGKWSNWESCDVTC GGGLSQRRRSCENGKIGEIGCEKDKESEQQKCNTQLCPEFTSWSDFTKCSVTCGGGTQKATRTCKNGRVGQEGCIGDTTK TRKCGEDECIGNFGTWSVWTKCSETCGNGIRTRSRSCEGGTKCIGKSQESEDCKVKECPVFGKWSQWTVCSNTCGGGQQS RSRDCLHTNNPEDCVGEASQSQNCNEQRCPGVWMPWTEWSECDVTCGEGTETKTRNCEGGEIGKPNCDSGEAEETRRCVL DACPSKWGNWGTWTFCSKSCDRGMKTRRRPCDGGKPGDGDCVPASAQKEEEACNEVTCRDCFDVAGFTWCATYFTIKENC KEYPAQARQYCALTCSLCPGLHEHWQSWGPCSSSCGTGFRTRTRECKNKELGCEGESSEEDVCKGPCQGFNPWGKWTTCT ESCNGGTRTRQRTCSFKKCDPDENGNTSKTDKENCNLEPCPGKWGDWGAWESCSTTCGDNGEQIARRTCEGGRAGGPGCL GLATKTRPCRNNNKCPGKWSAWTKWSQCSVTCGGKGTRTRTRTCEGGVEGQSDCPGSATQTEDCDEEKCTAKWGDWEDWG DCDKDCSRTRTRKCIGGTKGDRGCEGEGEQTQECDSSQCPTDGCDPNKIDLHIWCNSLTTANCYDPQYEQACPWTCCKVL GQVPCEDDPAQKDSYCVPYQAYCNDPTYIATFKQYCRKTCNFCE >XP_030828169.1 uncharacterized protein LOC752081 [Strongylocentrotus purpuratus] MNTMEFILIRCGRIAGGRNATNNMSRTKRLQSKVAKQTITPLLMIIMYFISSCHATDPGQLRLMGMHNGEGIVEITNQDQ WGLICASRWTMFDGDVACRQLGYEGVTRVMRVTPGREDRINAQVVLNGTNCEGMESRLVDCEHSGFGNFTESCQPMTLPW VSCIGADIPEVTDEVGGGDLDTSNHVPVLSGRILPPVATVPVETFPAISVRHVGHDSVSLSWLDWYDRLRASDPRAYRVR IIIKYRRVEVPGVQSTENYTIAAEVPTYWTDHTIRGLQPQTAYEFIVESVRLSMFGGEVIEPPSAPVYVRTVCGGPPPIR HLHVEAPSNNATVLHIHWTMPADNGCSSDEYVIEYRQENLDQCEETSLLPGQTNRLTLAGVTTMTHLVVAALQPYSSYTV FVSARNQFGRSRKVNSTKRTSETVPSDIPVNINHNFQSQNSLKLTWDPPSCGWRGGHIVTYAYMLIDINTDSVIHRGSTR REFVVLTGVDSLQRYKFLVAASTQRGVGPFAVSDIPVEPNILHICGMAQERTARISTGMRAPRGAAPWMAQLWNVQSGRM FCAGSIINEYWIITAAHCVEAQSHSASTLKIQLGDYDRLMPETHQRAYDVAEIVVHEGSQVQLDHDIALIKLSERIEFNN YVRPICFPTTKLAKSFLKSGSYGSVAGWGRKGDNMDYPRYLNQVFVPVVERKTCRRATDYDFTSNMFCAGFREANRGDAC EGDSGAPFSMQHANGRWYILGTVSWGDACDDQDKYGYYTRLHRYTSWIKRHTRVTTE >NP_611611.1 tracheal-prostasin [Drosophila melanogaster] MNRAWLCLLICLALSCGPSQSASQDRATNQTAASPLLKQSQNTFIQWVLSLLPQRPGSSDSENATLATLSSSSMMPDAAS TTSTTTPAPSSSTTTTRRATTPAPPTLNPPRNCSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQ FLLTASHCVYGFRKERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPG RSFKGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGT REHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKNLTKQACLCQQETKKIK >NP_501379.2 Serine protease svh-1 [Caenorhabditis elegans] MYIVIVTMRTILFFGIFFIFIFQCAKCIELKIFEDLLEVRSQSGLFFPLCSKSFHQKYGEQACASISSTFLSYSTVSLQQ YTYSVGCTTSVCFTFLSSFCKTGVKVFCSPSLCASGTLQIGSKCLSISTVPVQGYSEANYYCNPATLISSLKPTEIESIR DTILPTFADTRLFLTSGLRQGATWKWGNGDTVEQEVTGTGRCLALQAGNLVAIDCDSEAYVFCESGRECIARDKEYSGTA NRTSDGKMCLMWNDPTVLFRRERDLEILNHNFCRFVNDADGKKSATPVCYTKPNELSQCYIPPCPESFNDVVPIESGDSC PIGSISCDNGSKCISEKFQCDYEVDCNDGSDEHNCEDYLQYYELIGAYRLADNIIEVWTFIPHVQGCARKCRESLLMCEA FSYEPKSQTCLLTDTSQTFSSLARKITSLYYRRRFSTKDVEFQVENKVLYATKSAKKGHVCDDNYSREKLSSICRVLGFG DPIYTVESHQSESSLGPLQPTTLHPTNPSFDSPSSVSQMRRTSPSATLAPRLPAWNLSCLREPNCTSTVISTCEPIRCSH CQQAACGDGSCIRFDQLCNGQIDCQSGEDEDYCRANSFRLTNGSDTSGYLEVLFRSRWEPICADHLNGKISNSICDAMRL GEHGFILSTNATISSGYNVNCDVDCSIRRSSSCTRHARISCISQNGMSSASQCGLRYVEVNARDAAKSRIARVVGGFETV PGAFPWTAALRNKATKAHHCGASILDKTHLITAAHCFEEDERVSSYEVVVGDWDNNQTDGNEQIFYLQRIHFYPLYKDIF SHDIAILEIPYPGIEFNEYAQPICLPSKDFVYTPGRQCVVSGWGSMGLRYAERLQAALIPIINRFDCVNSSQIYSSMSRS AFCAGYLEGGIDSCQGDSGGPFACRREDGAFVLAGVISWGDGCAQKKQPGIYTMVAPYLSWISAIINGQPV >CAE1319957.1 F2 [Sepia pharaonis] MAERESHLWLECRHIIDTKGVKLESPGFPESYPSNHQCVYIIRSPPEETVTLTFHKFKLEKGENCQYDYVKIKDGESAAA DVLDKLCGVQDNKTYKSSGRSLRLDFVTDVGVSFMGFSATYTFSNCPLRCYNGGTCHNNTCKCSYGYQGPQCQYHKSCKD KPCENNATCSERRIGYHCHCTTQYTGYNCERKKYEVKLTGRERVQRRDNVEFKCFLNGKAARNAKWFFNENRLQVHTNDR AQIDKHVLYIHHVTEEDEGDYLCAVYKDDNAYYDVKKLKVSARCRLRVEEARNITVSSNQTARLFCPIRTHHGVKVSWKK NGHPIRLSSRKVAAGRTLKFESVISVDEGKYTCIAVGPNGCSAKADVWLTYERKDIPQECGRNNFHMHDHGLLAKIKSGH RAALGSAPWFVNFVEAAVTKSFCGGTLISRTHIVTAAHCIKLFKGPFDNANVHVYLGTQNCSGLGGIKVQIKKVTVHPRY NQSSLFDSDIAIVELQEKLYFNKIIQPLCLVDSAVVEEVAFYSGVFGTVVGCGMTSTGYHPHHLNEVKVPYVSNESCRST LHVGHNITSKMFCAGSIQAHQGDSCQGDSGGPYAVQLPSSSRWILVGIVSWGYKCDQSDSYGVYTNVGQFFDWITRIMSE P >tr|Q1RLV2|Q1RLV2_DANRE Christmas factor OS=Danio rerio OX=7955 GN=f9b PE=2 SV=1 MVKIYPVILMCSLLLEFWLSSGASVFLPRDLAESLLKRQKRYNTGGLEEMMKDNLERECY EERCSLEEAREVFENNEKTMKFWITYMDGDQCLSSPCQNGGKCEDGMNTYTCWCPARFSG KNCELEMAKQCHVNNGGCMHFCIVDKIYGAVCDCAEGYRLAVDGRSCEPRGQYPCGRLGK IIAQTLNSRALESTETVNQNQTISHINGTEYNTTESSPTDLSEMNSTSTPRNSLQNVSSS PILTNINNTTNNKYRIVGGDEAIPGEIPWQVVFLEKVNKIVFCGGSLLSEEWVITAAHCV EGKQGSFFIRVGEHDVSKMEGTESDHGIEEYHIHPRYNSQRSLYNHDIALLKLKKPVILF DYAVPICLGSKDFTENLLQSAENSLVSGWGRLRYGGIESNVLQKVELPYVDRIKCKGSST DSISRFMFCAGYSTVRKDACQGDSGGPHATRYKDTWFLTGIVSWGEECAKEGKYGIYTRI SKYMAWITNITRIRTGHMSNGDQQSLN >XP_043315927.1 coagulation factor IX [Cervus canadensis] MWYLNMIMAESPGLVTICLLGYLLSAECTVFLDRENATKILHRPKRYNSGKLEEFIPGNLERECREEKCSFEEAREVFEN TEKTTEFWKQYVDGDQCESNPCLNGGMCKDDINSYECWCQAGYEGKNCELDATCSIKNGRCKQFCKRDTDNKVVCSCTAG YRLAEDQKSCEPAVPFPCGRVSVSHTSKTLTRAETIFSNMNYENSSEAEIIWDNVTQSNQSFDDFNRVVGGEDAARGQFP WQVLLHGEIAAFCGGSIVNEKWVVTAAHCIKPGVKITVVAGEHNTEEPEPTEQKRNVIRAIPYHGYNASINKYSHDIALL ELDEPLKLNSYVTPICIADREYTNIFLKFGYGYVSGWGKVFNRGRSASILQYLKVPLVDRATCLRSTKFTIYNHMFCAGY HEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >KAB0345414.1 hypothetical protein FD754_022340 [Muntiacus muntjak] MTYVTGTPRTHSNLRGCESEVLKNKKHECRGFSLISSETPGLPLGLCSSKGNVLPIFLDRENATKILHRPKRYNSGKLEE FIPGNLERECREEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGMCKDDINSYECWCQAGYEGKNCELDATC SIKNGRCKQFCKRDTDNKVVCSCTAGYRLAEDQKSCEPAVPFPCGRVSVSHTSKTLTRAETIFSNMNYENSSEAEIILDN VTQSNQSFDDFNRVVGGEDAARGQFPWQVLLHGEIAAFCGGSIVNEKWVVTAAHCIKPGVKITVVAGEHNTEEPEPTEQK RNVIRAIPYHGYNASINKYSHDIALLELDEPLKLNSYVTPICIADREYTNIFLKFGYGYVSGWGKVFNRGRSASILQYLK VPLVDRATCLRSTKFTIYSHMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNW IKEKTKLT >KAF4026817.1 hypothetical protein G4228_019179 [Cervus hanglu yarkandensis] MWYLNMIMAESPGLVTICLLGYLLSAECTVFLDRENATKILHRPKRYNSGKLEEFIPGNLERECREEKCSFEEAREVFEN TEKTTEFWKQYVDATCSIKNGRCKQFCKRDTDNKVVCSCTAGYRLAEDQKSCEPAVPFPCGRVSVSHTSKTLTRAETIFS NMNYENSSEAEIIWDNVTQSNQSFDDFNRVVGGEDAARGQFPWQVLLHGEIAAFCGGSIVNEKWVVTAAHCIKPGVKITV VAGEHNTEEPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLKLNSYVTPICIADREYTNIFLKFGYGYVSGWG KVFNRGRSASILQYLKVPLVDRATCLRSTKFTIYNHMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAM KGKYGIYTKVSRYVNWIKEKTKLT >OWJ99698.1 F9 [Cervus elaphus hippelaphus] MCKDDINSYECWCQAGYEGKNCELDATCSIKNGRCKQFCKRDTDNKVVCSCTAGYRLAEDQKSCEPAVPFPCGRVSVSHT SKTLTRAETIFSNMNYENSSEAEIIWDNVTQSNQSFDDFNRVVGGEDAARGQFPWQVLLHGEIAAFCGGSIVNEKWVVTA AHCIKPGVKITVVAGEHNTEEPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLKLNSYVTPICIADREYTNIF LKFGYGYVSGWGKVFNRGRSASILQYLKVPLVDRATCLRSTKFTIYNHMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFL TGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >OCT66091.1 hypothetical protein XELAEV_18042345mg [Xenopus laevis] MVTFSSILIIYLLTSFCSAEKPVFLSNKSASSILVRQRRYNSGRLEEWVAGNLERECLEEKCNYEEAREVFENDDKTKEF WKQYIDGDQCLSKPCLNGGACKDDVSAYVCWCQQGYSGKNCELALPVICSIMNGGCDHLCRKDPVKKVICSCASGYKLAE NGKTCEAAVPYPCGEVSAPEALPKQETRSLLDFIELNETSTAHPDTTEKIKEVIVPVTADPKVRIVGGTDSLKGEFPWQV HLVSKNNLGFCGGSIINEKWIVTAAHCLLEGGEFKVVAGEHNTDISEGTEQYRKVAKAILYPTYNATMSRYNDDIALLEL ETPLELNDYVRPVCIGSMDFTEKLLKSNAFSMVSGWGDVRYNGRPAIILQKLAVPFINRAACKRSSRFSVYANMFCAGYS EGGKDTCQGDSGGPHVTQYKNLWFLTGITSWGEKCAEKEKYGVYTKVSRFTDWIRTTTKND >KAB0353393.1 hypothetical protein FD755_023904 [Muntiacus reevesi] MPPGTFGGGIMGANLLPPFIPGTEHILTRKLKSPESHHWLMRGKPVFREEGQRLAVIELLGQGSLQIQWGEVEMVGGETR RSAQVLLHGEIAAFCGGSIVNEKWVVTAAHCIKPGVKITVVAGEHNTEEPEPTEQKRNVIRAIPYHGYNASINKYSHDIA LLELDEPLKLNSYVTPICIADREYTNIFLKFGYGYVSGWGKVFNRGRSASILQYLKVPLVDRATCLRSTKFTIYSHMFCA GYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >XP_030252094.1 coagulation factor IX-like isoform X3 [Sparus aurata] MCVRISQLFGMAPFVSLSFLCLLLSDLELVYGAPAPASAPVFLSGEAADGVLRRHKRHNTGIFEEVLEGDLERECMEEVC DLEEAREIFENDGNTMEFWARYVDGDQCKSSPCQNQGSCNDHLGYYTCSCPSGFTGRNCEIVVAKRCDVNNGGCMHFCES MGTFGAKCSCAKGYKLLEDGRNCDPETEFPCGRTAMAPSGSAFTRSLLGHENASLENATSTTSPPSTPAGTTASLPATSE PTTIRSRKKLPWWRHVGAGPTEEPPRALKRIVGGEVVIPGEIPWQAALVARPSGQLFCGGSVLSERWVVTAAHCLVEGQG NFFIRVGEHSVFIHEDTEQDLEVMEQHIHPRYNASVSLYNHDIALIYLKSPITFSPTVRPICIGPKAFTEALVKEASPAT VSGWGRTRFLGFTADTLQKVKVPFTDRTECKSSSSARITPVMFCAGYYDEAKDACQGDSGGPHANSIHDTWFLTGIVSWG EECAKDGKYGVYTRLSLYYRWIKHVTGLTKHRLAFDVEDPDHEPDISPL >XP_015816844.1 PREDICTED: coagulation factor IX isoform X1 [Nothobranchius furzeri] MVRVCFLIVIASFHLEVHGLGDETKEENSGGVFVTQQVAHMVLPRQRRHNSGHVEEVFQKANLERECKEEVCSFEEAREV FEDDEKTNEFWTLYVDGDQCKPQPCQNGGECVDGISSYTCWCKPNYSGKNCEIYMTKLCSINNGGCLHFCVMENQRAACH CAAGYKLGTDKKSCEPLAQFSCGRVVLSHGSVTRSLMMSEYMPQNASTLNSTNDTSKSDDLSLLPPLTALSDIFLDFDTN ASSVDLDYGPTLSPDETEELNDTEMTLGGFSNPPNTTAENNPNRRIVGGNEAIPGEIPWQVTLMSPSASLGRALSFCGGS LLSELWVITAAHCLKDPDHTREYFFVRAGEHDVTVHEGPERDHEVVEQHVHPIYDYTVSRYNHDIALLKLATPVELSNKR RPICLGPKDFIQTLLRESTSSLVSGWGRQQFLGREANKLQKLSIPHVDRTLCKQSSSERITRFMFCAGYPDGEKDSCQGD SGGPHATNYKGTWFLTGIVSWGEECARKGKYGIYTRVSRYYKWVSETTGITETQ >XP_023805491.1 uncharacterized protein LOC101163720 [Oryzias latipes] MLWRLCLFLLTLHLTTAHVFIDGSAANQVLTRPRRANSLFEEMKQGNLERECVEERCDKEEAREIFEDDQKTQEFWSKYF DGDSCLSKPCVNNGRCKDGIGTYSCYCLEGFKGHNCEIVIPQLCETKNGGCEHFCHVRNRAVQCSCADGYYLAPNNKNCH SNNTFKCGAIVTDKVRTIFRYDRNSTEVNSTELIGNETFTDERFTPKHEAATLSTSNNSSQTQLEYVVEETVVPQRARHV RIVNGEDCPPGECPWQALLLNEDHQGFCGGTILSEHIILTAAHCMNQTRYMYVKLGKFDMLKTEKFEATHAVATIISHSK YTPLTYNNDIALIKLQNPIKFTKYILPACLPDQEFAEKVLMRQPEGLVSGFGRLGEGRAPSTILQRLSVPYVDRHVCMES TPLEILPQMFCAGYDKEAKDACQGDSGGPHVTRYHDTYFVTGVVSWGEGCARKGKYGIYTQVSKYIPWIRVATKRLMDLN LNRQRPKRHDGTIRRLFLTNIPRYSSLSSVEQTVNTIKSGSEVKVVGTPSSICESPKGVFVFEVVAAVSALAVDNMSASL LQLCLLACIPQVFSDGKVFPRMPGSEAVFLRSKRANRFLVEEILQGNLERECFEELCNYEEAREVFEDTAKTISFWTVYY DGDQCISSPCLNGGLCTDKVGGFSCSCPAPYHGPACEKGGLSTDEKYKFRGHELSVHQVTAPEISECPTGGPAACHQLCE VSGRSFTCSCTTGFKLHGDGRSCVPDVKFPCGRLPSATRPVCPHGHCPWQVTLMSSKGVELCGGVVLGQHSILTAARCLF LQSDSELRVSDFYVVAGNLLQQSALSDMQACNAEITILDVHLHDQFHSNHHDNNLALLKLSRPLLFGPTLIHLCLPTKDF SENILMHSGRKGNLQRQQLLYVTLDECRKSLNVSHSLTNKMFCMVEQGRKRGHHEDVQDSSVGPNRASAVDNSTQERSRT AGQNQTQINGRENITSSPHRRSEGGARLCNGLLQGSPVATMEKGTAFLTGLLLSSSTDCEGQVFIKVSRYLNWISNRLKV AENHTSSHISQSLVDLSEL >NP_032005.1 coagulation factor IX isoform 1 preproprotein [Mus musculus] MKHLNTVMAESPALITIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVRGNLERECIEERCS FEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDISSYECWCQVGFEGRNCELDATCNIKNGR CKQFCKNSPDNKVICSCTEGYQLAEDQKSCEPTVPFPCGRASISYSSKKITRAETVFSNMDYENSTEAVF IQDDITDGAILNNVTESSESLNDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLK PGDKIEVVAGEYNIDKKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANRE YTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTTFTIYNNMFCAGYREGGKDSCEGD SGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >NP_113728.1 coagulation factor IX precursor [Rattus norvegicus] MADAPGLIPIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVQGNLERECIEERCSFEEAREV FENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQAGFEGRNCELDATCSIKNGRCKQFCKN SPDNKIICSCTEGYQLAEDQKSCEPAVPFPCGRVSVAYNSKKITRAETVFSNTDYGNSTELILDDITNST ILDNLTENSEPINDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVA GEHNIDEKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANKEYTNIFLKFG SGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTKFSIYNNMFCAGYREGGKDSCEGDSGGPHVTEV EGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >NP_989674.1 coagulation factor IX precursor [Gallus gallus] MAKIPLILSFCLLEAFLGAESTVFIENKEASTVLSRTRRGNSNRLEELIPGNLERECIEEKCSFEEAREV FENTEKTMEFWKIYIDGDQCNSNPCKNGAVCKDGVSSYECMCPPGYGGRNCEIDSTCATKNGGCEHFCRH DTPQKAVCSCASGYKLHEDGKSCKPAVPYPCGRITAPEMRGKVTRTENTIERWNITAHDEGDAHDEALDI TEPPPPPTTSAAPAKIVPITKNDTRVVGGYDSVKGQLPWQVHLVDSRGLGFCGGSIINEKWVVTAAHCLE PGDNVTAVAGEYNTKEDDHTEQRRQVVKILPYPTYNRTRNKHHNDIALLELDQPLTFNSYVTPICIGSRD FTNNLLSNGPGTVSGWGSMLYRGRSAIVLQVLTVPFVDRVTCLKSTSTTILHSMFCAGYTAGGKDTCGGD SGGPYTNSIGETWFLTGVTSWGEECAKPGKYGIYTKVAKYVKWIRETTRLT >NP_001157475.1 coagulation factor IX [Sus scrofa] MRRLNVIMAESLGLVSICLLGYLLSAECTVFLDRENATKILHRPKRYNSGKLEEFVRGNLERECIEEKCS FEEAREVFENTEKTNEFWKQYVDGDQCEPNPCLNGGLCKDDINSYECWCQVGFEGKNCELDATCNIKNGR CKQFCKTGADSKVLCSCTTGYRLAPDQKSCEPAVPFPCGRVSVSHSPTTLTRAEIIFSNMDYENSTEVEP ILDSLTESNQSSDDFIRIVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVA GEYNTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNIFLKFG SGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHEGGKDSCQGDSGGPHVTEV EGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEKTKLT >NP_001003323.1 coagulation factor IX preproprotein [Canis lupus familiaris] MAEASGLVTVCLLGYLLSAECAVFLDRENATKILSRPKRYNSGKLEEFVRGNLERECIEEKCSFEEAREV FENTEKTTEFWKQYVDGDQCESNPCLNDGVCKDDINSYECWCRAGFEGKNCELDVTCNIKNGRCKQFCKL GPDNKVVCSCTTGYQLAEDQRSCEPAVPFPCGRVSVPHISMTRTRAETLFSNMDYENSTEVEKILDNVTQ PLNDFTRVVGGKDAKPGQFPWQVLLNGKVDAFCGGSIINEKWVVTAAHCIEPDVKITIVAGEHNTEKREH TEQKRNVIRTILHHSYNATINKYNHDIALLELDEPLTLNSYVTPICIADREYSNIFLKFGSGYVSGWGRV FNKGRSASILQYLKVPLVDRATCLRSTKFTIYNNMFCAGFHEGGKDSCQGDSGGPHVTEVEGISFLTGII SWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >XP_004022354.1 coagulation factor IX [Ovis aries] MWCLNMIMAESPGLVTICLLGYLLSAECTVFLDRENATKILHRPKRYNSGKLEEFVRGNLERECREEKCS FEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGMCKDDINSYECWCQAGFEGKNCELDATCSIKNGR CKQFCKRDADNKVVCSCTAGYRLAQDQKSCEPAVPFPCGRVSVLHTSKKLTRAETIFSNMNYENSSEAEI IWDNVTQSNQSFDDFNRVVGGEDAARGQFPWQVLLHGEIAAFCGGSIVNEKWVVTAAHCIKPGVKITVVA GEHNTEKPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLELNSYVTPICIADREYTNIFLKFG YGYVSGWGKVFNRGRSASILQYLKVPLVDRATCLRSTKFTIYNHMFCAGYHEGGKDSCQGDSGGPHVTEV EGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >NP_001129063.1 coagulation factor IX precursor [Pan troglodytes] MQRVNMIMAESPGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGNLERECMEEKCS FEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGR CEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLTRAETVFPDVDYVNSTEAETI LDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVDTGVKITVVAG EHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGS GYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVE GTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >NP_001009377.1 coagulation factor IX precursor [Felis catus] MRCLNMIMAEPPGLITICLLGYLLGADCTVFLDHEDATKVLSRPKRYNSGKLEEFVQGNLERECMEEKCS FEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQTGFEGKNCELDVTCNIKNGR CKQFCKLDADNKVVCSCTTGYQLAEDQKSCEPAVPFPCGRVSVPHISTTHTRAETLFLNMDYENSTTDYE NSAEAEKNVDNVTQPLNDLTRIVGGKTAKPGQFPWQVLLKGKIDAFCGGSIINEKWVVTAAHCINPDVEI TVVAGEHNTEETEHTEQKRNVIRTILHHSYNASVNKYSHDIALLELDEPLTLNSYVTPICVADREYTNTF LKFGYGYVSGWGKVFNKGRPATILQYLKVPLVDRATCLRSTKFTIYNNMFCAGFHEGGKDSCQGDSGGPH VTEVEGINFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >NP_001182654.1 coagulation factor IX [Oryctolagus cuniculus] MQFLNTIMAESPGLITICLLGYLLSAECTVFLDHENATKILNRAKRYNSGKLEEFVSGNLERECIEERCS FEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGSCKDDINAYECWCQYGFEGKNCELDSTCSIKNGR CEQFCRKNRNNKIICSCTEGYRLAENQKSCEPAVPFPCGRVSVSHASKKITRATTIFSNTEYENFTEAET IRGNVTQDAQSSDDFTRIVGGENAKPGQFPWQVLLNGKVEAFCGGSIINEKWVVTAAHCIKPDDNITVVA GEYNIQETENTEQKRNVIRIIPYHKYNATINKYNHDIALLELDKPLTLNSYVTPICIANREYTNIFLNFG SGYVSGWGRVFNRGRQASILQYLRVPFVDRATCLRSTKFTIYNNMFCAGFDVGGKDSCEGDSGGPHVTEV EGTSFLTGIISWGEECAIKGKYGVYTRVSWYVNWIKEKTKLT >XP_002832230.2 coagulation factor IX isoform X1 [Pongo abelii] MQRVNMIMAESPGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGNLERECMEEKCS FEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGR CKQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLTRAETVFPDVDYVNSTEAETI LDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLNGRRDAFCGGSIVNEKWIVTAAHCIETGDKITVVAG EHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGS GFVSGWGRVFNKGRSASILQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVE GTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >XP_010713519.1 LOW QUALITY PROTEIN: coagulation factor IX [Meleagris gallopavo] MAKIPLILSFCLLEAFLGAESAVFIENKEANTVLSRTRRGNSNRLEEFISGNLERECIEEKCSFEEAREV FENTEKTMEFWKIYIDGDQCNSNPCKNGAMCKDGVSSYECMCPPGYGGRNCEIDSTCATKNGGCEHFCRH DPPQKAVCSCASGYKLHEDGKSCKPEVPYPCGRITAPEMRGKVTRTENTIERWNITAHDEDDAHDEVLDI TELPPPPTTAAAPARTRADNXDDTRVVXGYDSVKGQLPWQVHLVDSSGLGFCGGSIINEKWVVTAAHCLK PGDNVTAVAGEYNTKEDDHTEQWRQVVKILPYPTYNRTRNKHHNDIALLELDQPLTFNSYVTPICIGSRD FTNNLLSNGPGTVSGWGSMLYRGRSAVILQVLTVPFVDRVTCLKSTSTTILQSMFCAGYTAGGKDTCGGD SGGPYANSIGETWFLTGVTSWGEECAKPGKYGIYTKVAKYVKWIRETTRLT >XP_003812356.2 coagulation factor IX [Pan paniscus] MQRVNMIMAESPGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGNLERECMEEKCS FEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGR CEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLTRAETVFPDVDYVNSTEAETI LDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVDTGVKITVVAG EHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGS GYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVE GTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >XP_004064996.1 coagulation factor IX [Gorilla gorilla gorilla] MQRVNMIMAESPGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSGKLEEFVQGNLERECMEEKCS FEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGR CEQFCKNSADNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLTRAETVFPDVDYVNSTEAETI LDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAG EHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFLKFGS GYVSGWGRVFHKGRSALILQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVE GTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >XP_005500580.1 coagulation factor IX [Columba livia] MANIPLVFSICLLGACLGATSTVFIENKEANSILHRQKRANSNRLEEVIPGNLERECIEEKCSFEEAREV FENTEKTMEFWKTYIDGDQCDPNPCKNGAVCKDAVSSYVCWCPAGYEGRNCEIDFTCAIKNGGCKHFCRH DPPQKVVCSCAAGYRLHEDGKSCEPTVPYPCGRITAPEAKSKLTRAINTFEHWNITTDDHDDTHDEVLDN ITETSTAATTKITPIIKTGTRVVGGSDSMRGEVPWQVHLVNSHGVGFCGASIINEKWVVTAAHCLKPGEI MAVAGEYNTNEDDKTEQWRKVVKILPHPTYNATINKHHNDIALLELDQPLSFNSYVTPICLGSRDFTNAL LKHGMGTVSGWGRKKSSATILQVLKVPFVDRPTCLKSTSTTILQNMFCAGYSAGGSDTCGGDSGGPYTTE IEGTWFLTGITSWGEECAKPGKYGIYTRVSKYVKWIKETTRLT >XP_005700488.1 PREDICTED: coagulation factor IX [Capra hircus] MWCLNMIMAESPGLVTICLLGYLLSAECTVFLDRENATKILHRPKRYNSGKLEEFVRGNLERECREEKCS FEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGMCKDDINSYECWCQAGFEGKNCELDATCSIKNGR CKQFCKRDADNKVVCSCTAGYRLAQDQKSCEPAVPFPCGRVSVLHTSKKLTRAETIFSNMNYENSSEAEI IWDNVTQSNQSFDDFNRVVGGEDAARGQFPWQVLLHGEIAAFCGGSIVNEKWIVTAAHCIKPGVKITVVA GEHNTEKPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLELNSYVTPICIADREYTNIFLKFG YGYVSGWGKVFNRGRSASILQYLKVPLVDRATCLRSTKFTIYNHMFCAGYHEGGKDSCQGDSGGPHVTEV EGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >XP_006031120.3 coagulation factor IX [Alligator sinensis] MAKLTLSVSVCLLGLFLQAECSVFIDKQQASSVLPRQKRFNSKRLEEVVAGNLERECIEEKCSYEEAREV FENEEKTMEFWKGYLDGDQCNPNPCKNGGSCQDELNSYVCWCLLGFEGRNCELDSTCATKNGGCKQFCRN DPQHKVVCSCAAGYTLHEDRKTCIPAVPFPCGRISAPEAKGKITRAMNTFEDWDITNSTEDEAADNATGS VTDYMTGNATDDVTPNLRRIVPVTKSDTRVVGGTDSKKGEIPWQVHLRHKDAGFCGGSIVNERWIVTAAH CLEPGAEITVVAGEHDTKAEDDTEQHRKVINIIPHPTYDAKVNKHHNDIALLELESPLQLNSYVTPICIA SKDFTNNLLKNGMGTVSGWGSLLFRGRPAQVLQVLKVPYVDRSTCLKSSSFSILQNMFCAGYPAGGKDTC TGDSGGPYATDIEGTWFLTGITSWGEDCAQKGKYGIYTRVSRYAKWIQNTTKLP >XP_006278300.1 PREDICTED: coagulation factor IX [Alligator mississippiensis] MAKLTLSVSVCLLGLFLQAECSVFIDNQQASSVLPRQKRFNSKRLEEVVSGNLERECIEEKCSYEEAREV FENEEKTMEFWKGYLDGDQCNPNPCKNGGSCQDELNSYVCWCPLGFEGRNCELDSTCATKNGGCKQFCRN DLQHKVVCSCAAGYTLHEDRKTCIPAVPFPCGRISAPEAKSKITRAMNTFEEWDITNSTEDEAADNAAGN VTDYTTGNPTNDVTPTPSRIVPITKPDTRVVGGTDSKKGEIPWQVHLRHKDAGFCGGSIVNERWIVTAAH CLVPGAEITVVAGEHDTKAEDDTEQHRKVINIIPHPTYDAKINKHHNDIALLELESPLQLNSYVTPICIA SKDFTNNLLKNGIGTVSGWGSLLFRGRPAQVLQVLKVPYVDRSTCLKSSSFSILQNMFCAGYPAGGKDTC AGDSGGPYTTDIEGTWFLTGITSWGEDCAQKGKYGIYTRVSRYVKWIQNMTKLP >XP_020770402.1 coagulation factor IX [Odocoileus virginianus texanus] MWYLNMIMAESPGLVTICLLGYLLSAECTVFLDRENATKILHRPKRYNSGKLEEFIPGNLERECKEEKCS FEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGMCKDDINSYECWCQAGYEGKNCELDATCSIKNGR CKQFCKRDTDNKVVCSCTAGYQLAEDQKSCEPAVPFPCGRVSVSHTSKKLTRAETIFSNMNYENSSEAEI IWDNVTQGNQSFDDFNRVVGGEDAARGQFPWQVLLHGEIAAFCGGSIVNEKWVVTAAHCIKPGVKITVVA GEHNTEEPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPFKLNSYVTPICIADREYTNIFLKFG YGYVSGWGKVFNRGRSASILQYLKVPLVDRATCLRSTKFTIYSHMFCAGYHEGGKDSCQGDSGGPHVTEV EGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT >XP_040179710.1 coagulation factor IX [Rana temporaria] MATAKYILIIFLLGYFCRAEKTVFLSAKSASGVLVRQKRYNSGGFEELSAGNLERECLEEKCTYEEAREV FENDEKTSEFWKQYVDGDQCISNPCLNGGVCKDDVSAYVCWCEHGYRGKNCEFELPVTCTINNGGCQQMC RENAEKKVTCSCASGYKLGEDGQTCQEIVQYPCGRVSAPEAVPKEETRTILDLEDFASNISSTEHHNSTE NIHLDDHSDDIVPVTVDPNVRIVGGTDSLKGEFPWQVHFINRNREGFCGGSIVNEKWIVTAAHCFITIPL GSFSVVAGEHNTAIKEGTEQYMEVTRIINHPSYNVSKNKYNNDIALVELEKPMVLNDYARPICIGHKDFT DRLLKIIPHSWVTGWGNLRYQGRPTVKLQKLAVPFVDRATCKRSSRYSVSTTMFCAGFADEEKDACQGDS GGPHATDFRNTWFLTGITSWGDKCAQKDRYGVYTRVSRFTDWILSTTKLP
Mafft alignment of selected proteins >sp|P00740|FA9_HUMAN Coagulation factor IX OS=Homo sapiens OX=9606 GN=F9 PE=1 SV=2 MQR----------------------------VNMI--MAESPGLITICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDHEN ANKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L NRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------QGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CMEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTERTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGSCK-----------------DDINSYECW CPFGFE-GKNCEL-------------------DVTCN--IKNGR-------------CEQ FCKNSADNKVVCSCT--EGYRLAENQKSCEPAVPFPCGRVS-VSQTSK---------LTR AETVFPD-V--DYVNST---------------------EA-------------------- ----------------ETILDNITQ------------STQS---------------FNDF TRVVGGEDAKPGQFPWQVVLNGK------VDAFCGGSIVNEKWIVTAAHCVETG------ VKITVVAGEHNIEE-TEHTEQKRNVIRIIPHHNYNAAINKYN-HDIALLELDEP-LV-LN SYVTPICIADKEYTNIF-LKFG-SGYVSGWGRVFHKG-RSALVLQYLRVPLVDRATCLRS T--KFTIYNN--MFCAGFHEGGR-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >tr|E7F301|E7F301_DANRE Christmas factor OS=Danio rerio OX=7955 GN=f9a PE=4 SV=2 -------------------------------------MASFILVLFPFLLLQ-------- ---------------------AAL------------------------------------ ---------------------------------------------------GSVFLDGEK ADSV-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L WRRRR------------------------------------------------------- ------------------------------------------------------------ ---ANTWLFEEFL----------PGNVE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CIEE--------------------------------------------- ------------------------------------------------------------ --------------------KCVLEEAREA------------------------------ -----------------------------FENDEKTMEFWASY----------------- ----------------VDGNQCKPSPCQNQGTCE-----------------DQMGTYSCN CLPGFV-GKNCEI-----------------VTAKKCD--VDNGG-------------CEH FCVLLESHKTQCQCA--YGYKLSEDGLTCEPIVKFPCGKTS-KPAVKTYGT----ASVTN TTAQFSN-M--TVKSTS---------------------SI-PKPDNLT------------ ---------------NPTNSKDIKEKLAPPRAKLPKWAFEEYLTSPAPT------VSGPK SRIIGGNSALPGEIPWQVALVSRST----QQVFCGGSILNPLWVITAAHCLLGNHN---- GSFYIRVGEHDVSK-IEGTEQNVDVIKLISHPRYNSKVSLFN-HDIALLRLRSP-IR-LT PTVRPICLGPMVFSNTL-LQSGTLATVSGWGRVRFQG-RSAATLQKIELPYVDRTVCKES S--SDPITHF--MFCAGHSDSPK-DACQGDSGGPHVMRYHN--TWFLTGIISWGEECAKK GKYGVYTQVGNYYRWIQHTMG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------VTTGALLT--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------NVDQ----------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >sp|P00741|FA9_BOVIN Coagulation factor IX OS=Bos taurus OX=9913 GN=F9 PE=1 SV=2 MWC----------------------------LNMI--MAESPGLVTICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDREN ATKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L HRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------RGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CKEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGMCK-----------------DDINSYECW CQAGFE-GTNCEL-------------------DATCS--IKNGR-------------CKQ FCKRDTDNKVVCSCT--DGYRLAEDQKSCEPAVPFPCGRVS-VSHISKK--------LTR AETIFSN-T--NYENSS---------------------EA-------------------- ----------------EIIWDNVTQ------------SNQS---------------FDEF SRVVGGEDAERGQFPWQVLLHGE------IAAFCGGSIVNEKWVVTAAHCIKPG------ VKITVVAGEHNTEK-PEPTEQKRNVIRAIPYHSYNASINKYS-HDIALLELDEP-LE-LN SYVTPICIADRDYTNIF-LKFG-YGYVSGWGKVFNRG-RSASILQYLKVPLVDRATCLRS T--KFSIYSH--MFCAGYHEGGK-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_031561359.1 atrial natriuretic peptide-converting enzyme-like isoform X3 [Actinia tenebrosa] MSKL---------------------------------QSMMCKLFVVCSLLAVCLQTTVS LECSYSLGVEKYIIPDSSLTASSEIDYWQGAAQARLNLVPYYTWYPSGWTPGANDGHPWL QIYLKHPYVVTGIATQGRGSLNVVQDWVRSYNLSYSMDGKTWKFCRSNVGSIKVFPGNTD ANTVRKNTISPPFTATYVRINPLTWSGQPSLRVELYGCLDSRYCGAKLGMQNGSIPDKHI TSSTQLSALYAASQGRLNNVPSALSGGCWRTGDMDYSPWLAVNLXKIFKVMAIGTQGNPV ADEWVTYYYVRFGHDGIHWNYIYDADMIKYYIGNEDRNTKTQNVLDQPIISQYIRIDPIL WNGERVALRVEFFGCMSVNKCFLSLGMEDRRIPDASLSASSALSNTNSPTYSRLHNQVAF QSLTGWSPSTTDQNPWLQISLGQLAIVAGVGIQGGSVQNWWETGKWVTSYKVGYSKDGIT WMTYSVNGVDKIF----------PGNTDSTSVVTNTFPTPIKALKIRIYPKTWNGGAYLR MELYGCRENQSVAVDHCDSNPCKNNATCVDHVANYTCTCASGFTGRNC------------ GTDIDDCNPNPCR--------NGAT--C----TDLVNGYICACRTGFTGQNCETDIDDCQ --SSPCRNYATCTDL--VNNYTCACASGFTGRNCEIDINECQSTPCKNQATCIDQVNNYT CACANGFSGRNCEIDIDDCENFPCE-NNATCIDHVYNYTCSCVSG----------FTGRN C-------------------EINFDECQST------------------------------ ----------------------------PCQNNATCIDHVNSYTCS-------------- ----CASGFTGSNCE-TDIDDCLPKPCENNATCT-----------------DLVNNYTCA CASGFT-GRNCEIDVN-------------ECQSEPC---LNNAT-------------C-- ---TDHVNNYTCSCA--SGFTGERCETDIDECQSSPCQNNGTCIDEVNGYI----CSCTS KYIGEQC-E--EVKTHC--------------------SSN-PCMNGGICVNKPTTYWCQC LYGYD-------GNQCEIVLNPNKE---------------------CG--------RRVQ ARIVGGESAFPGSWPWQVGLLAKED----KKHYCGGTLISKEWIVTAGHCVLFREP---- DEILVVLGEYDLSV-AEGNEVIKNVSTIISHPLYRWW--TSD-YDIALIKITEP-LKMYN RFIYPICLP---LNTEL-PPAGTQFTITGFGKLAHGG-AAAKRLQQAIVPLISHDLCKKT YEGKAIITDR--MMCAGHAEGGI-DSCQGDSGGPFIKEKSNY-CWYLYGVISWGIGCANP NSYGVYTNVLIARSWIKNQTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------V---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_016769420.1 trypsin-1 [Apis mellifera] MC-----------------------------------IRTTICLAVIVAVVA-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------C------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------TVNCEE--------------------------VQSSV---------------- -----IKEGINLNATQ-YNATINDDKNFWDWILA-------------------------- --------------------------------------GI-LSPSDSTT----------- ------------ENPKPGT---PEEC----------------LPCKCGL-------TNVQ RRIVGGVETQVNQYPWMVLLMYR------GRFYCGGSVISSFYVVTAAHCVDRFDP---- KLISVRILEHDRNSTTEAKTQEFRVDKVIKHSGYSTY--NYN-NDIALIKLKDA-IR-FE GKMRPVCLPERAK-----TFAGLNGTVTGWGATAESG-AISQTLQEVTVPILSNADCRAS KYPSQRITDN--MLCAGYKEGSK-DSCQGDSGGPLHVVNVD--TYQIVGIVSWGEGCARP GYPGVYTRVNRYLSWISRNTE--------------------------------------- ------------------------------------------------------------ ----------------------------DSCY---------------------------- ------------------------------------------------------------ -------------------C---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_038051917.1 trypsin-like [Patiria miniata] ----------------------------------------MLKFLVLCALAA-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------SVY----------------- ------------------------------ADC--------------------------- ------------------------------------------------------------ ----G------------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------VQV------ISPSL SKIVGGDEAVPGSWPWQVMLRKKYW--GGDYQFCGGTLINDQWVVTAAHCFYNYGN---I NLYSAVVGAHDRDA-VDATQSSVGLAQVFLHEDYNTR--TLD-NDITLLKLSSP-VS-LS DYVTPACLPQREV------ATGTDCVVTGWGDQETT--VDDPALQQVVVPIISTAQCNKA TWYGGDITDN--MICAGYSQGGK-DSCQGDSGGPFVCAASSG-AYELVGVVSWGYGCADA RNPGVYAKVLNYVDWINNIVA--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------NN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_039268100.1 A disintegrin and metalloproteinase with thrombospondin motifs adt-1-like [Styela clava] -------------------------------------MQIRLTILLLCLTLM-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------KARAE-------------------------------- ------EEE--------------------------------------------------- ------------------------------------------------------------ -----------CKD---------------------------------------------- ------------------------------------------------------------ --------------------KVSYCKRMKS------------------------------ -----------------------------FCDHAT----YKQYM---------------- ------------------LDNCI-------ATCK-------------------------- ---------KCRKDI---------------DPDGLCL--KDNGG-------------CEH TCDVEDKTIKKCSCF--SGYTLKKDGLTCTDVDE--CTIKGICLRGKH---------CTN VEGGFFC-D--EAKCTN------------------------------------------- --------------PEKPYLGRPDCC-----------TKEP-DTAECGV------TARGV ERIVGGNDSFLGQWPWQVYINID------TSIICGGTLINRNWVVTAGHCFKGFSS---E TKMELFFGVLELSKLKQGHVQKRNMKKHILYPNWNED--KFEINDIALIELDKP-VR-FN RWVRPVCLPNGEK-----PKIGTKCYAAGWGLQHEDDLSPATKLQHVDLPIVEPQKCIKA YKDEDTKVNRTIMMCAGYDEGGK-DSCRGDSGGPFVCQRCNSCGWYLAGVVSFGSGCAQK GFYGVYADVHYFEKWISEMTKIPVNNAKSCTGPYMETWSKWSTCTVTCGIGGKHTRTRQC LHKGKVSDQCNGPLKQTDDCPRIRCPRFGRFSDWSKCTKTCGG----------GLRTRIR ECLHGKIGQDGCPADDAVENEDCNK---QTCP---VWEDWSEWKTCTKTCGTGVEARTRK CIGGKPSDEGCDGKATEERKCNEELCPGWSDWGPFGRCSKTCGGGTQVSE-RQCIGKKCP GEDNKSQVCNKQL------CPVFGKWSNWESCDVTCGGGLSQRRRSCENGKIGEIGCEKD KESEQQKCNT-------QLCPEFTSWSDFTKCSVTCGGGTQKATRTCKNGRVGQEGCIGD TTKTRKCGEDECIGNFGTWSVWTKCSETCGNGIRTRSRSCEGGTKCIGKSQESEDCKVKE CPVFGKWSQWTVCSNT----CGG---GQQSRSRDCLHTNNPEDCVGEASQSQNCNEQRCP GVWMPWTEWSECDVTCGEGTETKTRNCEGGEIGKPNCDSGEAEETRRCVLDACPSKWGNW GTWTFCSKSCDRGMKTRRRPCDGGKPGDGDCVPASAQKEEEACN-EVTCRDCFDVAGFTW CATYFTIKENCKEYPAQARQYCALTCSLCPGLHEHWQSWGPCSSSCGTGFRTRTRECKNK ELGCEGESSEEDVCKGPCQGFNPWGKWTTCTESCNGGTRTRQRT--CSFKKCDPDENGNT SKTDKENCNLEPCPGKWGDWGAWESCSTTCGDNGEQIARRTCEGGRAGGPGCLGLATKTR PCRNNNKCPGKWSAWTKWSQCSVTCGGKGTRTRTRTCEGGVEGQSDCPGSATQTEDCDEE KCTAKWGDWEDWGDCDKDCSRTRTRKCIGGTKGDRGCEGEGEQTQECDSSQCPTDGCDPN KIDLHIWCNSLTTANCYDPQYEQACPWTCCKVLGQVPCEDDPAQKDSYCVPYQAYCNDPT YIA---TFKQYCRKTCNFCE- >XP_030828169.1 uncharacterized protein LOC752081 [Strongylocentrotus purpuratus] -------------------------------------MNTMEFILIRCGRIA-------- ------GGRNATNNMSRTKRLQSKV-----AKQ-------------------TIT--PLL M-------------------------------------------------IIMYFISSCH ATDPG----------------------QLRLM----------------GMHNGE------ ---------------------------------------------GIVEITNQDQWGLIC ASRWTMF----------------DGDVACRQLGYEG-----------------------V TRVMRV-----------------TPGRED-----------------------RINAQVVL --------------------------------------------------------NG-- ---TNCEGMESRL---VDCEHSGFGNFT-ESCQPMTLP-------------------WVS CIGADIPE-------------------VTDEVG--------------------------- GGDLDTSNHVP----------------------VLSGRILPPVAT-----VPVETFPAI- -----------SVRHVGHDSVSLSWLDWYDRLRASD-------PRAYRVRIIIKYRRVEV PGVQS-------------TENYTIAAEVPT---YWTDHTIRGLQP--------------- --------------------QTAYEFIVESVRLSMFGGEVIEPPSAPVYVRTVC---GGP PPIRHLHVEAPSNNATVLH---IHWTM-PADNGCSSDEYVIEYRQ--------------- ----------------ENLDQCEETSLLPGQTNRLTLAGVTTMTHLVVAALQPYSSYTVF VSARNQFGRSRKV-----------------NSTKRTSETVPSDI---------------- ----PVNINHNFQSQ--NSLKLTWDPPSCGWRGGHIVTYAYMLIDINTDSV------IHR GSTRREF-V--VLTGVDSLQRY---------------KFL-VAASTQRG----------- --------------VGPFAVSDIPV--------------EPNILHICGM------AQERT ARISTGMRAPRGAAPWMAQLWNVQS----GRMFCAGSIINEYWIITAAHCVEAQSHS--A STLKIQLGDYDRLM-PETHQRAYDVAEIVVHEGSQV---QLD-HDIALIKLSER-IE-FN NYVRPICFPTTKLAKSF-LKSGSYGSVAGWGRKGDNM-DYPRYLNQVFVPVVERKTCRRA T--DYDFTSN--MFCAGFREANRGDACEGDSGAPFSMQHANG-RWYILGTVSWGDACDDQ DKYGYYTRLHRYTSWIKRHTR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------VTTE------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >NP_611611.1 tracheal-prostasin [Drosophila melanogaster] -------------------------------------MNRAWLCLLICLALS-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CGP--------------------------SQSAS---------------- -----QDRATNQTAA--SPLLKQSQNTFIQWVLSLLPQRPG-SSDSENATL----ATLSS SSMMPDA-A--STTSTT--------------------T---PAPSSSTTTTRRAT----- -------------TPAPPTLNPPRNC----------------SDCVCGI-------ANIQ KRIVGGQETEVHQYPWVAMLLYG------GRFYCAASLLNDQFLLTASHCVYGFRK---- ERISVRLLEHDRKM-SHMQKIDRKVAEVITHPKYNAR--NYD-NDIAIIKLDEP-VE-FN EVLHPVCMPTPGR-----SFKGENGIVTGWGALKVGG-PTSDTLQEVQVPILSQDECRKS RY-GNKITDN--MLCGGYDEGGK-DSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKA GYPGVYARVNRYGTWIKNLTK--------------------------------------- ------------------------------------------------------------ ----------------------------QACL---------------------------- ------------------------------------------------------------ -------------------C---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------QQETK----------------------------- ------------KIK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >NP_501379.2 Serine protease svh-1 [Caenorhabditis elegans] MYI------------------------------VIVTMRTILFFGIFFIFIFQCAKCI-- ----------ELKIFEDLLEVRSQ----------------------------SGLFFPLC SKSFHQKYGEQACASISSTFLSYSTVSLQQY--TYSVGCTT--------SVCFTFLSSFC KTGVK------------------VFC-SPSL------C-------ASGTLQIGS------ ---------------------------------------------KCLSISTVPVQGYSE A----NY-YCN------------PATLISSLKPTEIESIR------DTILPTFADTRLFL TSGLR------------------------------------------------------- --------------------------------------------------------QGAT WKWGNGDTVEQEVTGTGRCLALQAGNLVAIDCDSE---------------------AYVF CE-SG-RE-------------------CIARDKEYSGTANRTSDGKMCLMWNDPTVLFRR ERDLEILNHNFCRFVNDADGKKSATPVCYTKPNELSQCYIPPCPESFNDVVPIESGDSCP IGSISCDNGSKCISEKFQCDYEVDCNDGSDEHNCEDYLQYYELIGAYRLADNIIEVWTFI PHVQGCA--RKCRESLLMCEAFSYEPKSQTCLLTDTSQTFSSLARKITSLYYRRRFSTKD VEFQVENKVLYATKSAKKGHVCDDNYSREKL-------------------SSICRVLGFG DPIYTVESHQSESSLGPLQPTTLHPTNPSFDSPSSVSQMRRTSPSATLAPRLPAWNLSCL REPNCTSTVI-STCEPIRCSHCQQAACGDGSCIRF----------------DQLCNGQID CQSGED-EDYCRANSF-------------R---------LTNGSDTSGYLEVLFRSRWEP ICADHLNGKISNSIC--DAMRLGEHGFILSTNATISSGYNV-NCDVDCS--------IRR SSSCTRH-A--RISCIS-------------------QNG--------------------- -------------------MSSASQC-----------GLRYVEVNARDA------AKSRI ARVVGGFETVPGAFPWTAALRNKAT----KAHHCGASILDKTHLITAAHCFEEDER---V SSYEVVVGDWDNNQ-TDGNEQIFYLQRIHFYPLYKD---IFS-HDIAILEIPYPGIE-FN EYAQPICLPSKDFV----YTPGRQCVVSGWGSMGL---RYAERLQAALIPIINRFDCVNS SQIYSSMSRS--AFCAGYLEGGI-DSCQGDSGGPFACRREDG-AFVLAGVISWGDGCAQK KQPGIYTMVAPYLSWISAIIN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------GQ-------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------PV------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >CAE1319957.1 F2 [Sepia pharaonis] M------------------------------------AERESHLWLECRHII-------- --------------DTKGVKLESP-------------------------------GFP-- ----------------------------ESYPSNHQ---------------CVYIIRSPP EETVT-----------------LTF--------------------HKFKLEKGE------ --------------------------NC-------------------------------- -----QYDYVK------------------------------------------------I KDGES------------------------------------------------------- ------------------------------------------------------------ ---AAADVLDKLCGV--------QDNKTYKS----------------------------- ---SG-RS---------------------------------------------------- ----------------------------------LRLDFVTDVGVSFMGFSATYTFSNCP L---RCYNGGTCHNN--------------------------------------------- -----------------------------TC----------------------------- --------------------KCSYGYQGPQ------------------------------ ----------------------------------------CQY----------------- ------------------HKSCKDKPCENNATCS-----------------ERRIGYHCH CTTQYT-GYNCERKKYEVKLTGRERVQRRDNVEFKCF--LNGKA----------ARNAKW FFNENRLQVHTNDRAQIDKHVLYIHHVTEEDEGDYLCAVYK-DDNAYYDVK--KLKVSAR CRLRVEEARNITVSSNQTARLFCPIRTHHGVKVSWKKNGH-PIRLSSRKVAAGRTLKFES VISVD------EGKYTCIAVGPNGCS---AKADVWLTYERKDIPQECGRNNFHMHDHGLL AKIKSGHRAALGSAPWFVNFVEAAV----TKSFCGGTLISRTHIVTAAHCIKLFKGPFDN ANVHVYLGTQNCSG-LGGIK--VQIKKVTVHPRYNQS-SLFD-SDIAIVELQEK-LY-FN KIIQPLCLVDSAVVEEVAFYSGVFGTVVGCGMTSTG--YHPHHLNEVKVPYVSNESCRST LHVGHNITSK--MFCAGSIQAHQGDSCQGDSGGPYAVQLPSSSRWILVGIVSWGYKCDQS DSYGVYTNVGQFFDWITRIMSEP------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >tr|Q1RLV2|Q1RLV2_DANRE Christmas factor OS=Danio rerio OX=7955 GN=f9b PE=2 SV=1 -------------------------------------MVKIYPVILMCSLLL-------- -----------------EFWLSSG------------------------------------ ---------------------------------------------------ASVFLPRDL AESL-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L KRQKR------------------------------------------------------- ------------------------------------------------------------ ---YNTGGLEEMM----------KDNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CYEE--------------------------------------------- ------------------------------------------------------------ --------------------RCSLEEAREV------------------------------ -----------------------------FENNEKTMKFWITY----------------- ----------------MDGDQCLSSPCQNGGKCE-----------------DGMNTYTCW CPARFS-GKNCEL-----------------EMAKQCH--VNNGG-------------CMH FCIVDKIYGAVCDCA--EGYRLAVDGRSCEPRGQYPCGRLG-KIIAQTLNS----RALES TETVNQN-Q--TISHIN---------------------GT-EYNTTES------------ ---------------SPTDLSEMNST-STPRNSLQNVSSSPILTNINNT-------TNNK YRIVGGDEAIPGEIPWQVVFLEKVN----KIVFCGGSLLSEEWVITAAHCVEGKQ----- GSFFIRVGEHDVSK-MEGTESDHGIEEYHIHPRYNSQRSLYN-HDIALLKLKKP-VI-LF DYAVPICLGSKDFTENL-LQSAENSLVSGWGRLRYGG-IESNVLQKVELPYVDRIKCKGS S--TDSISRF--MFCAGYSTVRK-DACQGDSGGPHATRYKD--TWFLTGIVSWGEECAKE GKYGIYTRISKYMAWITNITR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------IRTGHMSN--------------------------------------- -------------------------------------GDQQSLN---------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_043315927.1 coagulation factor IX [Cervus canadensis] MWY----------------------------LNMI--MAESPGLVTICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDREN ATKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L HRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFI----------PGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CREE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGMCK-----------------DDINSYECW CQAGYE-GKNCEL-------------------DATCS--IKNGR-------------CKQ FCKRDTDNKVVCSCT--AGYRLAEDQKSCEPAVPFPCGRVS-VSHTSKT--------LTR AETIFSN-M--NYENSS---------------------EA-------------------- ----------------EIIWDNVTQ------------SNQS---------------FDDF NRVVGGEDAARGQFPWQVLLHGE------IAAFCGGSIVNEKWVVTAAHCIKPG------ VKITVVAGEHNTEE-PEPTEQKRNVIRAIPYHGYNASINKYS-HDIALLELDEP-LK-LN SYVTPICIADREYTNIF-LKFG-YGYVSGWGKVFNRG-RSASILQYLKVPLVDRATCLRS T--KFTIYNH--MFCAGYHEGGK-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >KAB0345414.1 hypothetical protein FD754_022340 [Muntiacus muntjak] MTYVTGTPRTHSNLRGCESEVLKNKKHECRGFSLI--SSETPGLP----L---------- -----------------GLCSSKGN----------------------------------- --------------------------------------------------VLPIFLDREN ATKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L HRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFI----------PGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CREE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGMCK-----------------DDINSYECW CQAGYE-GKNCEL-------------------DATCS--IKNGR-------------CKQ FCKRDTDNKVVCSCT--AGYRLAEDQKSCEPAVPFPCGRVS-VSHTSKT--------LTR AETIFSN-M--NYENSS---------------------EA-------------------- ----------------EIILDNVTQ------------SNQS---------------FDDF NRVVGGEDAARGQFPWQVLLHGE------IAAFCGGSIVNEKWVVTAAHCIKPG------ VKITVVAGEHNTEE-PEPTEQKRNVIRAIPYHGYNASINKYS-HDIALLELDEP-LK-LN SYVTPICIADREYTNIF-LKFG-YGYVSGWGKVFNRG-RSASILQYLKVPLVDRATCLRS T--KFTIYSH--MFCAGYHEGGK-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >KAF4026817.1 hypothetical protein G4228_019179 [Cervus hanglu yarkandensis] MWY----------------------------LNMI--MAESPGLVTICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDREN ATKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L HRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFI----------PGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CREE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTTEFWKQY----------------- ----------------V------------------------------------------- --------------------------------DATCS--IKNGR-------------CKQ FCKRDTDNKVVCSCT--AGYRLAEDQKSCEPAVPFPCGRVS-VSHTSKT--------LTR AETIFSN-M--NYENSS---------------------EA-------------------- ----------------EIIWDNVTQ------------SNQS---------------FDDF NRVVGGEDAARGQFPWQVLLHGE------IAAFCGGSIVNEKWVVTAAHCIKPG------ VKITVVAGEHNTEE-PEPTEQKRNVIRAIPYHGYNASINKYS-HDIALLELDEP-LK-LN SYVTPICIADREYTNIF-LKFG-YGYVSGWGKVFNRG-RSASILQYLKVPLVDRATCLRS T--KFTIYNH--MFCAGYHEGGK-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >OWJ99698.1 F9 [Cervus elaphus hippelaphus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------MCK-----------------DDINSYECW CQAGYE-GKNCEL-------------------DATCS--IKNGR-------------CKQ FCKRDTDNKVVCSCT--AGYRLAEDQKSCEPAVPFPCGRVS-VSHTSKT--------LTR AETIFSN-M--NYENSS---------------------EA-------------------- ----------------EIIWDNVTQ------------SNQS---------------FDDF NRVVGGEDAARGQFPWQVLLHGE------IAAFCGGSIVNEKWVVTAAHCIKPG------ VKITVVAGEHNTEE-PEPTEQKRNVIRAIPYHGYNASINKYS-HDIALLELDEP-LK-LN SYVTPICIADREYTNIF-LKFG-YGYVSGWGKVFNRG-RSASILQYLKVPLVDRATCLRS T--KFTIYNH--MFCAGYHEGGK-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >OCT66091.1 hypothetical protein XELAEV_18042345mg [Xenopus laevis] -------------------------------------MVTFSSILIIYLL---------- -----------------TSFCSAE------------------------------------ ---------------------------------------------------KPVFLSNKS ASSI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L VRQRR------------------------------------------------------- ------------------------------------------------------------ ---YNSGRLEEWV----------AGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CLEE--------------------------------------------- ------------------------------------------------------------ --------------------KCNYEEAREV------------------------------ -----------------------------FENDDKTKEFWKQY----------------- ----------------IDGDQCLSKPCLNGGACK-----------------DDVSAYVCW CQQGYS-GKNCEL-----------------ALPVICS--IMNGG-------------CDH LCRKDPVKKVICSCA--SGYKLAENGKTCEAAVPYPCGEVS-APEALPK-------QETR SLLDFIE-L--NETSTA------------------------------------------- ---------------HPDTTEKI-------------------KEVIVPV------TADPK VRIVGGTDSLKGEFPWQVHLVSKN-----NLGFCGGSIINEKWIVTAAHCLLEG------ GEFKVVAGEHNTDI-SEGTEQYRKVAKAILYPTYNATMSRYN-DDIALLELETP-LE-LN DYVRPVCIGSMDFTEKL-LKSNAFSMVSGWGDVRYNG-RPAIILQKLAVPFINRAACKRS S--RFSVYAN--MFCAGYSEGGK-DTCQGDSGGPHVTQYKN--LWFLTGITSWGEKCAEK EKYGVYTKVSRFTDWIRTTTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------ND--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >KAB0353393.1 hypothetical protein FD755_023904 [Muntiacus reevesi] ---------------------------------------MPPGTFG-------------- -----------------GGIMGANL----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------LPPFI----------PG----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------TE-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------HILTRKLKSPE---------------SHHW--------LMR GKPVFRE-E--GQRLAVI--------------------EL-LGQGSL------------- ----------------QIQWGE-------------------------------------- VEMVGGETRRSA----QVLLHGE------IAAFCGGSIVNEKWVVTAAHCIKPG------ VKITVVAGEHNTEE-PEPTEQKRNVIRAIPYHGYNASINKYS-HDIALLELDEP-LK-LN SYVTPICIADREYTNIF-LKFG-YGYVSGWGKVFNRG-RSASILQYLKVPLVDRATCLRS T--KFTIYSH--MFCAGYHEGGK-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_030252094.1 coagulation factor IX-like isoform X3 [Sparus aurata] MCV---------------------------RISQLFGMAPFVSLSFLCLLLS-------- ----------DLE-LVYGAPAPAS------------------------------------ ---------------------------------------------------APVFLSGEA ADGV-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L RRHKR------------------------------------------------------- ------------------------------------------------------------ ---HNTGIFEEVL----------EGDLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CMEE--------------------------------------------- ------------------------------------------------------------ --------------------VCDLEEAREI------------------------------ -----------------------------FENDGNTMEFWARY----------------- ----------------VDGDQCKSSPCQNQGSCN-----------------DHLGYYTCS CPSGFT-GRNCEI-----------------VVAKRCD--VNNGG-------------CMH FCESMGTFGAKCSCA--KGYKLLEDGRNCDPETEFPCGRTA-MAPSGSA--------FTR SLLGHENASLENATSTT---------------------SP-PSTPAGTTASLPAT----- --------------SEPTTIRSRKKLPWWRHVGAGP-TEEP---------------PRAL KRIVGGEVVIPGEIPWQAALVARPS----GQLFCGGSVLSERWVVTAAHCLVEGQ----- GNFFIRVGEHSVFI-HEDTEQDLEVMEQHIHPRYNASVSLYN-HDIALIYLKSP-IT-FS PTVRPICIGPKAFTEAL-VKEASPATVSGWGRTRFLG-FTADTLQKVKVPFTDRTECKSS S--SARITPV--MFCAGYYDEAK-DACQGDSGGPHANSIHD--TWFLTGIVSWGEECAKD GKYGVYTRLSLYYRWIKHVTG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LTKHRLAF--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------DVEDPDHEP------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------DISPL >XP_015816844.1 PREDICTED: coagulation factor IX isoform X1 [Nothobranchius furzeri] -------------------------------------MVRVCFLIVIASFHL-------- ----------EVHGLGDETKEENS------------------------------------ ---------------------------------------------------GGVFVTQQV AHMV-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L PRQRR------------------------------------------------------- ------------------------------------------------------------ ---HNSGHVEEVF---------QKANLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CKEE--------------------------------------------- ------------------------------------------------------------ --------------------VCSFEEAREV------------------------------ -----------------------------FEDDEKTNEFWTLY----------------- ----------------VDGDQCKPQPCQNGGECV-----------------DGISSYTCW CKPNYS-GKNCEI-----------------YMTKLCS--INNGG-------------CLH FCV-MENQRAACHCA--AGYKLGTDKKSCEPLAQFSCGRVV-LSHGSVT------RSLMM SEYMPQNAS--TLNSTN---------------------DT-SKSDDLSLL-PPLTALSDI FLDFDTNASSVDLDYGPTLSPDETEELNDTEMTLGGFSNPPNTTA----------ENNPN RRIVGGNEAIPGEIPWQVTLMSPSASLGRALSFCGGSLLSELWVITAAHCLKDPDHT--R EYFFVRAGEHDVTV-HEGPERDHEVVEQHVHPIYDYTVSRYN-HDIALLKLATP-VE-LS NKRRPICLGPKDFIQTL-LRESTSSLVSGWGRQQFLG-REANKLQKLSIPHVDRTLCKQS S--SERITRF--MFCAGYPDGEK-DSCQGDSGGPHATNYKG--TWFLTGIVSWGEECARK GKYGIYTRVSRYYKWVSETTG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------ITETQ------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_023805491.1 uncharacterized protein LOC101163720 [Oryzias latipes] M------------------------------------------LWRLCLFLL-------- -----------------TLHLTT------------------------------------- ---------------------------------------------------AHVFIDGSA ANQV-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L TRPRR------------------------------------------------------- ------------------------------------------------------------ ---ANS-LFEEMK----------QGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CVEE--------------------------------------------- ------------------------------------------------------------ --------------------RCDKEEAREI------------------------------ -----------------------------FEDDQKTQEFWSKY----------------- ----------------FDGDSCLSKPCVNNGRCK-----------------DGIGTYSCY CLEGFK-GHNCEI-----------------VIPQLCE--TKNGG-------------CEH FCH-VRNRAVQCSCA--DGYYLAPNNKNCHSNNTFKCGAIV-TDKVRTIFRYDRNSTEVN STELIGN-E--TFTDER---------------------FT-PKHEAAT------------ -------------------LSTSNNS-------SQTQLEYVVEETVVPQ-------RARH VRIVNGEDCPPGECPWQALLLNED-----HQGFCGGTILSEHIILTAAHCMNQT------ RYMYVKLGKFDMLK-TEKFEATHAVATIISHSKYTPL--TYN-NDIALIKLQNP-IK-FT KYILPACLPDQEFAEKV-LMRQPEGLVSGFGRLGEGR-APSTILQRLSVPYVDRHVCMES T--PLEILPQ--MFCAGYDKEAK-DACQGDSGGPHVTRYHD--TYFVTGVVSWGEGCARK GKYGIYTQVSKYIPWIRVATKRLMDL--------------------------NLNRQRPK RHDGTIR--------------RLFLTNIPRYSSLSSVEQTVNTIKSGSEVKVVGTPSSIC ESPKGVFVFEVVAAVSALAVDNMSASLLQLCLLACIPQVFSDGKVFPRMPGSEAVFLRSK RANRFLVEEILQGNL--ERECFEELCNYEEAREVFEDTAKTISFWTVYYDGDQCISSPCL ----NGGLCTDKVGGFSCSCPAP---YHGPACE---KGGLSTDEKYKFRGH--ELSVHQV TAPEISECPTGGPAACHQLCE--VSGRSFT-CSCTTGFKLHGDGRSCVPDVKFPCGRLPS ATRP-----------------------VCPHG---------------------------H CP----W-QVTLMSSKGVELCGGVVLGQHSI----------------------------- -------------LTAARCLFLQS-------------DS----ELR--VSD--------- ----FYVVA-------------------GNLLQQSALSDMQACNAEITILD--------- ------VHLHDQFHSNHHDNNLALLKLSRPLL------FGP----------TLIHLC--- ---------------LPTKDFSE----NILMHSGRKGNLQRQQLLYVTLDECRKSLNVSH SLTNKMFCMVE------------------------------------------------- ------------------------------QGRKRGHHEDVQDSSVGPNRASAVDNSTQE RSRTA-GQNQTQINGRENITSSPHRRSEGGAR---------------------------- ------LCNGLLQGSPVATMEKGTAFLTGLLLSSSTDCEGQVFIKVSR---YLNWISNRL KVAENHTSSHISQSLVDLSEL >NP_032005.1 coagulation factor IX isoform 1 preproprotein [Mus musculus] MKH----------------------------LNTV--MAESPALITIFLL---------- -----------------GYLLSTE------------------------------------ ---------------------------------------------------CAVFLDREN ATKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L TRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------RGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CIEE--------------------------------------------- ------------------------------------------------------------ --------------------RCSFEEAREV------------------------------ -----------------------------FENTEKTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGICK-----------------DDISSYECW CQVGFE-GRNCEL-------------------DATCN--IKNGR-------------CKQ FCKNSPDNKVICSCT--EGYQLAEDQKSCEPTVPFPCGRAS-ISYSSKK--------ITR AETVFSN-M--DYENST---------------------EAVFIQDDIT------------ ---------------DGAILNNVTE------------SSES---------------LNDF TRVVGGENAKPGQIPWQVILNGE------IEAFCGGAIINEKWIVTAAHCLKPG------ DKIEVVAGEYNIDK-KEDTEQRRNVIRTIPHHQYNATINKYS-HDIALLELDKP-LI-LN SYVTPICVANREYTNIF-LKFG-SGYVSGWGKVFNKG-RQASILQYLRVPLVDRATCLRS T--TFTIYNN--MFCAGYREGGK-DSCEGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >NP_113728.1 coagulation factor IX precursor [Rattus norvegicus] -------------------------------------MADAPGLIPIFLL---------- -----------------GYLLSTE------------------------------------ ---------------------------------------------------CAVFLDREN ATKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L TRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------QGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CIEE--------------------------------------------- ------------------------------------------------------------ --------------------RCSFEEAREV------------------------------ -----------------------------FENTEKTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGICK-----------------DDINSYECW CQAGFE-GRNCEL-------------------DATCS--IKNGR-------------CKQ FCKNSPDNKIICSCT--EGYQLAEDQKSCEPAVPFPCGRVS-VAYNSKK--------ITR AETVFSN-T--DYGNST---------------------EL--ILDDIT------------ ---------------NSTILDNLTE------------NSEP---------------INDF TRVVGGENAKPGQIPWQVILNGE------IEAFCGGAIINEKWIVTAAHCLKPG------ DKIEVVAGEHNIDE-KEDTEQRRNVIRTIPHHQYNATINKYS-HDIALLELDKP-LI-LN SYVTPICVANKEYTNIF-LKFG-SGYVSGWGKVFNKG-RQASILQYLRVPLVDRATCLRS T--KFSIYNN--MFCAGYREGGK-DSCEGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >NP_989674.1 coagulation factor IX precursor [Gallus gallus] -------------------------------------MAKIPLILSFCLL---------- -----------------EAFLGAE------------------------------------ ---------------------------------------------------STVFIENKE ASTV-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L SRTRR------------------------------------------------------- ------------------------------------------------------------ ---GNSNRLEELI----------PGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CIEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTMEFWKIY----------------- ----------------IDGDQCNSNPCKNGAVCK-----------------DGVSSYECM CPPGYG-GRNCEI-------------------DSTCA--TKNGG-------------CEH FCRHDTPQKAVCSCA--SGYKLHEDGKSCKPAVPYPCGRIT-APEMRGK--------VTR TENTIER-W--NITAHD---------------------EG------DA------------ ---------------HDEALD-ITEP-------PPPPTTSAAPAKIVPI-------TKND TRVVGGYDSVKGQLPWQVHLVDSR-----GLGFCGGSIINEKWVVTAAHCLEPG------ DNVTAVAGEYNTKE-DDHTEQRRQVVKILPYPTYNRTRNKHH-NDIALLELDQP-LT-FN SYVTPICIGSRDFTNNL-LSNG-PGTVSGWGSMLYRG-RSAIVLQVLTVPFVDRVTCLKS T--STTILHS--MFCAGYTAGGK-DTCGGDSGGPYTNSIGE--TWFLTGVTSWGEECAKP GKYGIYTKVAKYVKWIRETTR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >NP_001157475.1 coagulation factor IX [Sus scrofa] MRR----------------------------LNVI--MAESLGLVSICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDREN ATKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L HRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------RGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CIEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTNEFWKQY----------------- ----------------VDGDQCEPNPCLNGGLCK-----------------DDINSYECW CQVGFE-GKNCEL-------------------DATCN--IKNGR-------------CKQ FCKTGADSKVLCSCT--TGYRLAPDQKSCEPAVPFPCGRVS-VSHSPTT--------LTR AEIIFSN-M--DYENST---------------------EV-------------------- ----------------EPILDSLTE------------SNQS---------------SDDF IRIVGGENAKPGQFPWQVLLNGK------IDAFCGGSIINEKWVVTAAHCIEPG------ VKITVVAGEYNTEE-TEPTEQRRNVIRAIPHHSYNATVNKYS-HDIALLELDEP-LT-LN SYVTPICIADKEYTNIF-LKFG-SGYVSGWGRVFNRG-RSATILQYLKVPLVDRATCLRS T--KFTIYSN--MFCAGFHEGGK-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAVK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >NP_001003323.1 coagulation factor IX preproprotein [Canis lupus familiaris] -------------------------------------MAEASGLVTVCLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CAVFLDREN ATKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L SRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------RGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CIEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTTEFWKQY----------------- ----------------VDGDQCESNPCLNDGVCK-----------------DDINSYECW CRAGFE-GKNCEL-------------------DVTCN--IKNGR-------------CKQ FCKLGPDNKVVCSCT--TGYQLAEDQRSCEPAVPFPCGRVS-VPHISMT--------RTR AETLFSN-M--DYENST---------------------EV-------------------- ----------------EKILDNVT---------------QP---------------LNDF TRVVGGKDAKPGQFPWQVLLNGK------VDAFCGGSIINEKWVVTAAHCIEPD------ VKITIVAGEHNTEK-REHTEQKRNVIRTILHHSYNATINKYN-HDIALLELDEP-LT-LN SYVTPICIADREYSNIF-LKFG-SGYVSGWGRVFNKG-RSASILQYLKVPLVDRATCLRS T--KFTIYNN--MFCAGFHEGGK-DSCQGDSGGPHVTEVEG--ISFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_004022354.1 coagulation factor IX [Ovis aries] MWC----------------------------LNMI--MAESPGLVTICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDREN ATKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L HRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------RGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CREE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGMCK-----------------DDINSYECW CQAGFE-GKNCEL-------------------DATCS--IKNGR-------------CKQ FCKRDADNKVVCSCT--AGYRLAQDQKSCEPAVPFPCGRVS-VLHTSKK--------LTR AETIFSN-M--NYENSS---------------------EA-------------------- ----------------EIIWDNVTQ------------SNQS---------------FDDF NRVVGGEDAARGQFPWQVLLHGE------IAAFCGGSIVNEKWVVTAAHCIKPG------ VKITVVAGEHNTEK-PEPTEQKRNVIRAIPYHGYNASINKYS-HDIALLELDEP-LE-LN SYVTPICIADREYTNIF-LKFG-YGYVSGWGKVFNRG-RSASILQYLKVPLVDRATCLRS T--KFTIYNH--MFCAGYHEGGK-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >NP_001129063.1 coagulation factor IX precursor [Pan troglodytes] MQR----------------------------VNMI--MAESPGLITICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDHEN ANKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L NRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------QGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CMEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTERTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGSCK-----------------DDINSYECW CPFGFE-GKNCEL-------------------DVTCN--IKNGR-------------CEQ FCKNSADNKVVCSCT--EGYRLAENQKSCEPAVPFPCGRVS-VSQTSK---------LTR AETVFPD-V--DYVNST---------------------EA-------------------- ----------------ETILDNITQ------------STQS---------------FNDF TRVVGGEDAKPGQFPWQVVLNGK------VDAFCGGSIVNEKWIVTAAHCVDTG------ VKITVVAGEHNIEE-TEHTEQKRNVIRIIPHHNYNAAINKYN-HDIALLELDEP-LV-LN SYVTPICIADKEYTNIF-LKFG-SGYVSGWGRVFHKG-RSALVLQYLRVPLVDRATCLRS T--KFTIYNN--MFCAGFHEGGR-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >NP_001009377.1 coagulation factor IX precursor [Felis catus] MRC----------------------------LNMI--MAEPPGLITICLL---------- -----------------GYLLGAD------------------------------------ ---------------------------------------------------CTVFLDHED ATKV-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L SRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------QGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CMEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGICK-----------------DDINSYECW CQTGFE-GKNCEL-------------------DVTCN--IKNGR-------------CKQ FCKLDADNKVVCSCT--TGYQLAEDQKSCEPAVPFPCGRVS-VPHISTT--------HTR AETLFLN-M--DYENSTT--DY------------ENSAEA-------------------- ----------------EKNVDNVT---------------QP---------------LNDL TRIVGGKTAKPGQFPWQVLLKGK------IDAFCGGSIINEKWVVTAAHCINPD------ VEITVVAGEHNTEE-TEHTEQKRNVIRTILHHSYNASVNKYS-HDIALLELDEP-LT-LN SYVTPICVADREYTNTF-LKFG-YGYVSGWGKVFNKG-RPATILQYLKVPLVDRATCLRS T--KFTIYNN--MFCAGFHEGGK-DSCQGDSGGPHVTEVEG--INFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >NP_001182654.1 coagulation factor IX [Oryctolagus cuniculus] MQF----------------------------LNTI--MAESPGLITICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDHEN ATKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L NRAKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------SGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CIEE--------------------------------------------- ------------------------------------------------------------ --------------------RCSFEEAREV------------------------------ -----------------------------FENTEKTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGSCK-----------------DDINAYECW CQYGFE-GKNCEL-------------------DSTCS--IKNGR-------------CEQ FCRKNRNNKIICSCT--EGYRLAENQKSCEPAVPFPCGRVS-VSHASKK--------ITR ATTIFSN-T--EYENFT---------------------EA-------------------- ----------------ETIRGNVTQ------------DAQS---------------SDDF TRIVGGENAKPGQFPWQVLLNGK------VEAFCGGSIINEKWVVTAAHCIKPD------ DNITVVAGEYNIQE-TENTEQKRNVIRIIPYHKYNATINKYN-HDIALLELDKP-LT-LN SYVTPICIANREYTNIF-LNFG-SGYVSGWGRVFNRG-RQASILQYLRVPFVDRATCLRS T--KFTIYNN--MFCAGFDVGGK-DSCEGDSGGPHVTEVEG--TSFLTGIISWGEECAIK GKYGVYTRVSWYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_002832230.2 coagulation factor IX isoform X1 [Pongo abelii] MQR----------------------------VNMI--MAESPGLITICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDHEN ANKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L NRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------QGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CMEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTERTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGSCK-----------------DDINSYECW CPFGFE-GKNCEL-------------------DVTCN--IKNGR-------------CKQ FCKNSADNKVVCSCT--EGYRLAENQKSCEPAVPFPCGRVS-VSQTSK---------LTR AETVFPD-V--DYVNST---------------------EA-------------------- ----------------ETILDNITQ------------STQS---------------FNDF TRVVGGEDAKPGQFPWQVVLNGR------RDAFCGGSIVNEKWIVTAAHCIETG------ DKITVVAGEHNIEE-TEHTEQKRNVIRIIPHHNYNAAINKYN-HDIALLELDEP-LV-LN SYVTPICIADKEYTNIF-LKFG-SGFVSGWGRVFNKG-RSASILQYLRVPLVDRATCLRS T--KFTIYNN--MFCAGFHEGGR-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_010713519.1 LOW QUALITY PROTEIN: coagulation factor IX [Meleagris gallopavo] -------------------------------------MAKIPLILSFCLL---------- -----------------EAFLGAE------------------------------------ ---------------------------------------------------SAVFIENKE ANTV-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L SRTRR------------------------------------------------------- ------------------------------------------------------------ ---GNSNRLEEFI----------SGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CIEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTMEFWKIY----------------- ----------------IDGDQCNSNPCKNGAMCK-----------------DGVSSYECM CPPGYG-GRNCEI-------------------DSTCA--TKNGG-------------CEH FCRHDPPQKAVCSCA--SGYKLHEDGKSCKPEVPYPCGRIT-APEMRGK--------VTR TENTIER-W--NITAHD---------------------ED------DA------------ ---------------HDEVLD-ITEL-------PPPPTTAAAPARTRAD-------NXDD TRVVXGYDSVKGQLPWQVHLVDSS-----GLGFCGGSIINEKWVVTAAHCLKPG------ DNVTAVAGEYNTKE-DDHTEQWRQVVKILPYPTYNRTRNKHH-NDIALLELDQP-LT-FN SYVTPICIGSRDFTNNL-LSNG-PGTVSGWGSMLYRG-RSAVILQVLTVPFVDRVTCLKS T--STTILQS--MFCAGYTAGGK-DTCGGDSGGPYANSIGE--TWFLTGVTSWGEECAKP GKYGIYTKVAKYVKWIRETTR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_003812356.2 coagulation factor IX [Pan paniscus] MQR----------------------------VNMI--MAESPGLITICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDHEN ANKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L NRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------QGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CMEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTERTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGSCK-----------------DDINSYECW CPFGFE-GKNCEL-------------------DVTCN--IKNGR-------------CEQ FCKNSADNKVVCSCT--EGYRLAENQKSCEPAVPFPCGRVS-VSQTSK---------LTR AETVFPD-V--DYVNST---------------------EA-------------------- ----------------ETILDNITQ------------STQS---------------FNDF TRVVGGEDAKPGQFPWQVVLNGK------VDAFCGGSIVNEKWIVTAAHCVDTG------ VKITVVAGEHNIEE-TEHTEQKRNVIRIIPHHNYNAAINKYN-HDIALLELDEP-LV-LN SYVTPICIADKEYTNIF-LKFG-SGYVSGWGRVFHKG-RSALVLQYLRVPLVDRATCLRS T--KFTIYNN--MFCAGFHEGGR-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_004064996.1 coagulation factor IX [Gorilla gorilla gorilla] MQR----------------------------VNMI--MAESPGLITICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDHEN ANKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L NRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------QGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CMEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTERTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGSCK-----------------DDINSYECW CPFGFE-GKNCEL-------------------DVTCN--IKNGR-------------CEQ FCKNSADNKVVCSCT--EGYRLAENQKSCEPAVPFPCGRVS-VSQTSK---------LTR AETVFPD-V--DYVNST---------------------EA-------------------- ----------------ETILDNITQ------------STQS---------------FNDF TRVVGGEDAKPGQFPWQVVLNGK------VDAFCGGSIVNEKWIVTAAHCVETG------ VKITVVAGEHNIEE-TEHTEQKRNVIRIIPHHNYNAAINKYN-HDIALLELDEP-LV-LN SYVTPICIADKEYTNIF-LKFG-SGYVSGWGRVFHKG-RSALILQYLRVPLVDRATCLRS T--KFTIYNN--MFCAGFHEGGR-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_005500580.1 coagulation factor IX [Columba livia] -------------------------------------MANIPLVFSICLL---------- -----------------GACLGAT------------------------------------ ---------------------------------------------------STVFIENKE ANSI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L HRQKR------------------------------------------------------- ------------------------------------------------------------ ---ANSNRLEEVI----------PGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CIEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTMEFWKTY----------------- ----------------IDGDQCDPNPCKNGAVCK-----------------DAVSSYVCW CPAGYE-GRNCEI-------------------DFTCA--IKNGG-------------CKH FCRHDPPQKVVCSCA--AGYRLHEDGKSCEPTVPYPCGRIT-APEAKSK--------LTR AINTFEH-W--NITTDD---------------------HD------DT------------ ---------------HDEVLDNITE------------TSTAATTKITPI-------IKTG TRVVGGSDSMRGEVPWQVHLVNSH-----GVGFCGASIINEKWVVTAAHCLKPG------ -EIMAVAGEYNTNE-DDKTEQWRKVVKILPHPTYNATINKHH-NDIALLELDQP-LS-FN SYVTPICLGSRDFTNAL-LKHG-MGTVSGWGR---KK-SSATILQVLKVPFVDRPTCLKS T--STTILQN--MFCAGYSAGGS-DTCGGDSGGPYTTEIEG--TWFLTGITSWGEECAKP GKYGIYTRVSKYVKWIKETTR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_005700488.1 PREDICTED: coagulation factor IX [Capra hircus] MWC----------------------------LNMI--MAESPGLVTICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDREN ATKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L HRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFV----------RGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CREE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGMCK-----------------DDINSYECW CQAGFE-GKNCEL-------------------DATCS--IKNGR-------------CKQ FCKRDADNKVVCSCT--AGYRLAQDQKSCEPAVPFPCGRVS-VLHTSKK--------LTR AETIFSN-M--NYENSS---------------------EA-------------------- ----------------EIIWDNVTQ------------SNQS---------------FDDF NRVVGGEDAARGQFPWQVLLHGE------IAAFCGGSIVNEKWIVTAAHCIKPG------ VKITVVAGEHNTEK-PEPTEQKRNVIRAIPYHGYNASINKYS-HDIALLELDEP-LE-LN SYVTPICIADREYTNIF-LKFG-YGYVSGWGKVFNRG-RSASILQYLKVPLVDRATCLRS T--KFTIYNH--MFCAGYHEGGK-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_006031120.3 coagulation factor IX [Alligator sinensis] -------------------------------------MAKLTLSVSVCLL---------- -----------------GLFLQAE------------------------------------ ---------------------------------------------------CSVFIDKQQ ASSV-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L PRQKR------------------------------------------------------- ------------------------------------------------------------ ---FNSKRLEEVV----------AGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CIEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSYEEAREV------------------------------ -----------------------------FENEEKTMEFWKGY----------------- ----------------LDGDQCNPNPCKNGGSCQ-----------------DELNSYVCW CLLGFE-GRNCEL-------------------DSTCA--TKNGG-------------CKQ FCRNDPQHKVVCSCA--AGYTLHEDRKTCIPAVPFPCGRIS-APEAKGK--------ITR AMNTFED-W--DITNST---------------------ED------EA------------ ---------------ADNATGSVTDY----MTGNATDDVTPNLRRIVPV-------TKSD TRVVGGTDSKKGEIPWQVHLRHK------DAGFCGGSIVNERWIVTAAHCLEPG------ AEITVVAGEHDTKA-EDDTEQHRKVINIIPHPTYDAKVNKHH-NDIALLELESP-LQ-LN SYVTPICIASKDFTNNL-LKNG-MGTVSGWGSLLFRG-RPAQVLQVLKVPYVDRSTCLKS S--SFSILQN--MFCAGYPAGGK-DTCTGDSGGPYATDIEG--TWFLTGITSWGEDCAQK GKYGIYTRVSRYAKWIQNTTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LP--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_006278300.1 PREDICTED: coagulation factor IX [Alligator mississippiensis] -------------------------------------MAKLTLSVSVCLL---------- -----------------GLFLQAE------------------------------------ ---------------------------------------------------CSVFIDNQQ ASSV-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L PRQKR------------------------------------------------------- ------------------------------------------------------------ ---FNSKRLEEVV----------SGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CIEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSYEEAREV------------------------------ -----------------------------FENEEKTMEFWKGY----------------- ----------------LDGDQCNPNPCKNGGSCQ-----------------DELNSYVCW CPLGFE-GRNCEL-------------------DSTCA--TKNGG-------------CKQ FCRNDLQHKVVCSCA--AGYTLHEDRKTCIPAVPFPCGRIS-APEAKSK--------ITR AMNTFEE-W--DITNST---------------------ED------EA------------ ---------------ADNAAGNVTDY----TTGNPTNDVTPTPSRIVPI-------TKPD TRVVGGTDSKKGEIPWQVHLRHK------DAGFCGGSIVNERWIVTAAHCLVPG------ AEITVVAGEHDTKA-EDDTEQHRKVINIIPHPTYDAKINKHH-NDIALLELESP-LQ-LN SYVTPICIASKDFTNNL-LKNG-IGTVSGWGSLLFRG-RPAQVLQVLKVPYVDRSTCLKS S--SFSILQN--MFCAGYPAGGK-DTCAGDSGGPYTTDIEG--TWFLTGITSWGEDCAQK GKYGIYTRVSRYVKWIQNMTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LP--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_020770402.1 coagulation factor IX [Odocoileus virginianus texanus] MWY----------------------------LNMI--MAESPGLVTICLL---------- -----------------GYLLSAE------------------------------------ ---------------------------------------------------CTVFLDREN ATKI-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L HRPKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGKLEEFI----------PGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CKEE--------------------------------------------- ------------------------------------------------------------ --------------------KCSFEEAREV------------------------------ -----------------------------FENTEKTTEFWKQY----------------- ----------------VDGDQCESNPCLNGGMCK-----------------DDINSYECW CQAGYE-GKNCEL-------------------DATCS--IKNGR-------------CKQ FCKRDTDNKVVCSCT--AGYQLAEDQKSCEPAVPFPCGRVS-VSHTSKK--------LTR AETIFSN-M--NYENSS---------------------EA-------------------- ----------------EIIWDNVTQ------------GNQS---------------FDDF NRVVGGEDAARGQFPWQVLLHGE------IAAFCGGSIVNEKWVVTAAHCIKPG------ VKITVVAGEHNTEE-PEPTEQKRNVIRAIPYHGYNASINKYS-HDIALLELDEP-FK-LN SYVTPICIADREYTNIF-LKFG-YGYVSGWGKVFNRG-RSASILQYLKVPLVDRATCLRS T--KFTIYSH--MFCAGYHEGGK-DSCQGDSGGPHVTEVEG--TSFLTGIISWGEECAMK GKYGIYTKVSRYVNWIKEKTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LT--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------- >XP_040179710.1 coagulation factor IX [Rana temporaria] -------------------------------------MATAKYILIIFLL---------- -----------------GYFCRAE------------------------------------ ---------------------------------------------------KTVFLSAKS ASGV-------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------------------------L VRQKR------------------------------------------------------- ------------------------------------------------------------ ---YNSGGFEELS----------AGNLE-------------------------------- ------RE---------------------------------------------------- ------------------------------------------------------------ -----------CLEE--------------------------------------------- ------------------------------------------------------------ --------------------KCTYEEAREV------------------------------ -----------------------------FENDEKTSEFWKQY----------------- ----------------VDGDQCISNPCLNGGVCK-----------------DDVSAYVCW CEHGYR-GKNCEF-----------------ELPVTCT--INNGG-------------CQQ MCRENAEKKVTCSCA--SGYKLGEDGQTCQEIVQYPCGRVS-APEAVPK-------EETR TILDLED-FASNISSTE------------------------------------------- ---------------HHNSTENIHL--------------DDHSDDIVPV------TVDPN VRIVGGTDSLKGEFPWQVHFINRN-----REGFCGGSIVNEKWIVTAAHCFITIPL---- GSFSVVAGEHNTAI-KEGTEQYMEVTRIINHPSYNVSKNKYN-NDIALVELEKP-MV-LN DYARPICIGHKDFTDRL-LKIIPHSWVTGWGNLRYQG-RPTVKLQKLAVPFVDRATCKRS S--RYSVSTT--MFCAGFADEEK-DACQGDSGGPHATDFRN--TWFLTGITSWGDKCAQK DRYGVYTRVSRFTDWILSTTK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------LP--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------
BMGE Cleaned alignment of selected proteins >sp|P00740|FA9_HUMAN Coagulation factor IX OS=Homo sapiens OX=9606 GN=F9 PE=1 SV=2 GLITICLLGYLLSAETVFLDHNANKILNRPKRYNSGKLEEFVQGNLEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCEQFCKNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSLTRAEILDNITRVVGGEDAKPGQFPWQVVLNAFCGGSIVNEKWIVTAAHCVETGKITVVAGEHNITEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLNSYVTPICIADKEYTNIFSGYVSGWGRVFRSALVLQYLRVPLVDRATCLRSTMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >tr|E7F301|E7F301_DANRE Christmas factor OS=Danio rerio OX=7955 GN=f9a PE=4 SV=2 LVLFPFLL----AALSVFLDGKADSVLWRRRRANTWLFEEFLPGNVEKCVLEEAREAFENDEKTMEFWASYVDGNQCKPSPCQNQGTCEDQMGTYSCNCLPGFVGKNCEIAKKCDVDNGGCEHFCVHKTQCQCAYGYKLSEDGLTCEPIVKFPCGKTSVTNTTNSKDISRIIGGNSALPGEIPWQVALVVFCGGSILNPLWVITAAHCLLGNSFYIRVGEHDVIEGTEQNVDVIKLISHPRYNSKVSLFNHDIALLRLRSPLTPTVRPICLGPMVFSNTLLATVSGWGRVRRSAATLQKIELPYVDRTVCKESSMFCAGHSDSPKDACQGDSGGPHVMRYHNTWFLTGIISWGEECAKKGKYGVYTQVGNYYRWIQHTMG >sp|P00741|FA9_BOVIN Coagulation factor IX OS=Bos taurus OX=9913 GN=F9 PE=1 SV=2 GLVTICLLGYLLSAETVFLDRNATKILHRPKRYNSGKLEEFVRGNLEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGMCKDDINSYECWCQAGFEGTNCELDATCSIKNGRCKQFCKNKVVCSCTDGYRLAEDQKSCEPAVPFPCGRVSLTRAEIWDNVSRVVGGEDAERGQFPWQVLLHAFCGGSIVNEKWVVTAAHCIKPGKITVVAGEHNTPEPTEQKRNVIRAIPYHSYNASINKYSHDIALLELDEPLNSYVTPICIADRDYTNIFYGYVSGWGKVFRSASILQYLKVPLVDRATCLRSTMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >XP_031561359.1 atrial natriuretic peptide-converting enzyme-like isoform X3 [Actinia tenebrosa] KLFVVCSLSLTASSEKVFPGNDANTVLWNGERYSVNGVDKIFPGNTDEINFDECQSTCQNNATCIDHVNSYTDIDDCLPKPCENNATCTDLVNNYTCACASGFTGRNCEISEPC-LNNATC-----NNYTCSCASGFTGERCETDIDECQSSPCQNNGCTSKYVLNPNARIVGGESAFPGSWPWQVGLLHYCGGTLISKEWIVTAGHCVLFREILVVLGEYDLAEGNEVIKNVSTIISHPLYRWW--TSDYDIALIKITEPYNRFIYPICLP---LNTELQFTITGFGKLAAAAKRLQQAIVPLISHDLCKKTYMMCAGHAEGGIDSCQGDSGGPFIKEKSNCWYLYGVISWGIGCANPNSYGVYTNVLIARSWIKNQTN >XP_016769420.1 trypsin-1 [Apis mellifera] CLAVIVAV------------------------------------------------------------------------------------------------TVNCEE-----VQSSV------EGINLNATYNATINDDKNFWDWILA------------T---PRRIVGGVETQVNQYPWMVLLMFYCGGSVISSFYVVTAAHCVDRFLISVRILEHDRTEAKTQEFRVDKVIKHSGYSTY--NYNNDIALIKLKDAFEGKMRPVCLPERAK----NGTVTGWGATAAISQTLQEVTVPILSNADCRASKMLCAGYKEGSKDSCQGDSGGPLHVVNVDTYQIVGIVSWGEGCARPGYPGVYTRVNRYLSWISRNTE >XP_038051917.1 trypsin-like [Patiria miniata] KFLVLCAL------------------------------------------------------------SVY--------------ADC--------------------------------------------------------------------------------SKIVGGDEAVPGSWPWQVMLRQFCGGTLINDQWVVTAAHCFYNYLYSAVVGAHDRVDATQSSVGLAQVFLHEDYNTR--TLDNDITLLKLSSPLSDYVTPACLPQREV----DCVVTGWGDQEVDDPALQQVVVPIISTAQCNKATMICAGYSQGGKDSCQGDSGGPFVCAASSAYELVGVVSWGYGCADARNPGVYAKVLNYVDWINNIVA >XP_039268100.1 A disintegrin and metalloproteinase with thrombospondin motifs adt-1-like [Styela clava] TILLLCLT----------------------------------KARAEKVSYCKRMKSFCDHAT----YKQY--LDNCI-------ATCK-----------------KCRKDGLCLKDNGGCEHTCDTIKKCSCFSGYTLKKDGLTCTDVDE--CTIKGCTNVEYLGRPERIVGGNDSFLGQWPWQVYINIICGGTLINRNWVVTAGHCFKGFKMELFFGVLELKQGHVQKRNMKKHILYPNWNED--KFENDIALIELDKPFNRWVRPVCLPNGEK----KCYAAGWGLQHSPATKLQHVDLPIVEPQKCIKAYMMCAGYDEGGKDSCRGDSGGPFVCQRCNGWYLAGVVSFGSGCAQKGFYGVYADVHYFEKWISEMTK >XP_030828169.1 uncharacterized protein LOC752081 [Strongylocentrotus purpuratus] FILIRCGRTKRLQSKMYFISSHATDPVTRVMRTNCEGMESRLFGNFTQTAYEFIVESADNGCSSDEYVIEYENLDQCEETSLLPGQTNRQPYSSYTVFVSARNQGRSRKVTKRTSVPSDI------INHNFQSQNSLKLTWDPPSCGWRGGHIVTYAYIHRGSAVSDIARISTGMRAPRGAAPWMAQLWMFCAGSIINEYWIITAAHCVEAQTLKIQLGDYDRPETHQRAYDVAEIVVHEGSQV---QLDHDIALIKLSERFNNYVRPICFPTTKLAKSFYGSVAGWGRKGDYPRYLNQVFVPVVERKTCRRATMFCAGFREANRDACEGDSGAPFSMQHANRWYILGTVSWGDACDDQDKYGYYTRLHRYTSWIKRHTR >NP_611611.1 tracheal-prostasin [Drosophila melanogaster] LCLLICLA---------------------------------------------------------------------------------------------------CGP-----SQSAS------RATNQTAASPLLKQSQNTFIQWVLSLLPQRPGLSSSSTLNPPKRIVGGQETEVHQYPWVAMLLFYCAASLLNDQFLLTASHCVYGFRISVRLLEHDRSHMQKIDRKVAEVITHPKYNAR--NYDNDIAIIKLDEPFNEVLHPVCMPTPGR----NGIVTGWGALKPTSDTLQEVQVPILSQDECRKSRMLCGGYDEGGKDSCQGDSGGPLHIVASGEHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKNLTK >NP_501379.2 Serine protease svh-1 [Caenorhabditis elegans] FFGIFFIFLLEVRSQFTFLSSCKTGVLTSGLRGNGDTVEQEVAGNLVVCDDNYSREKFDSPSSVSQMRRTSIRCSHCQQAACGDGSCIRDQLCNGQIDCQSGEDEDYCRA-----LTNGSWEPICAGKISNSICDAMRLGEHGFILSTNATISSGYNVIRRSS-MSSAARVVGGFETVPGAFPWTAALRHHCGASILDKTHLITAAHCFEEDSYEVVVGDWDNTDGNEQIFYLQRIHFYPLYKD---IFSHDIAILEIPYPFNEYAQPICLPSKDFV---QCVVSGWGSMGRYAERLQAALIPIINRFDCVNSSAFCAGYLEGGIDSCQGDSGGPFACRREDAFVLAGVISWGDGCAQKKQPGIYTMVAPYLSWISAIIN >CAE1319957.1 F2 [Sepia pharaonis] HLWLECRHGVKLESPVYIIRSPEETVIKDGESAAADVLDKLCQDNKTKCSYGYQGPQ-----------CQY--HKSCKDKPCENNATCSERRIGYHCHCTTQYTGYNCEREFKCFLNGKAAKWFFNQVHTNDRADKHVLYIHHVTEEDEGDYLCAVYKSARCRAVGPNAKIKSGHRAALGSAPWFVNFVSFCGGTLISRTHIVTAAHCIKLFNVHVYLGTQNCLGGIK--VQIKKVTVHPRYNQS-SLFDSDIAIVELQEKFNKIIQPLCLVDSAVVEEVFGTVVGCGMTSYHPHHLNEVKVPYVSNESCRSTLMFCAGSIQAHQDSCQGDSGGPYAVQLPSRWILVGIVSWGYKCDQSDSYGVYTNVGQFFDWITRIMS >tr|Q1RLV2|Q1RLV2_DANRE Christmas factor OS=Danio rerio OX=7955 GN=f9b PE=2 SV=1 PVILMCSLEFWLSSGSVFLPRLAESLLKRQKRYNTGGLEEMMKDNLERCSLEEAREVFENNEKTMKFWITYMDGDQCLSSPCQNGGKCEDGMNTYTCWCPARFSGKNCELAKQCHVNNGGCMHFCIYGAVCDCAEGYRLAVDGRSCEPRGQYPCGRLGLESTEDLSEMYRIVGGDEAIPGEIPWQVVFLVFCGGSLLSEEWVITAAHCVEGKSFFIRVGEHDVMEGTESDHGIEEYHIHPRYNSQRSLYNHDIALLKLKKPLFDYAVPICLGSKDFTENLNSLVSGWGRLRIESNVLQKVELPYVDRIKCKGSSMFCAGYSTVRKDACQGDSGGPHATRYKDTWFLTGIVSWGEECAKEGKYGIYTRISKYMAWITNITR >XP_043315927.1 coagulation factor IX [Cervus canadensis] GLVTICLLGYLLSAETVFLDRNATKILHRPKRYNSGKLEEFIPGNLEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGMCKDDINSYECWCQAGYEGKNCELDATCSIKNGRCKQFCKNKVVCSCTAGYRLAEDQKSCEPAVPFPCGRVSLTRAEIWDNVNRVVGGEDAARGQFPWQVLLHAFCGGSIVNEKWVVTAAHCIKPGKITVVAGEHNTPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLNSYVTPICIADREYTNIFYGYVSGWGKVFRSASILQYLKVPLVDRATCLRSTMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >KAB0345414.1 hypothetical protein FD754_022340 [Muntiacus muntjak] GLP----LGLCSSKGPIFLDRNATKILHRPKRYNSGKLEEFIPGNLEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGMCKDDINSYECWCQAGYEGKNCELDATCSIKNGRCKQFCKNKVVCSCTAGYRLAEDQKSCEPAVPFPCGRVSLTRAEILDNVNRVVGGEDAARGQFPWQVLLHAFCGGSIVNEKWVVTAAHCIKPGKITVVAGEHNTPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLNSYVTPICIADREYTNIFYGYVSGWGKVFRSASILQYLKVPLVDRATCLRSTMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >KAF4026817.1 hypothetical protein G4228_019179 [Cervus hanglu yarkandensis] GLVTICLLGYLLSAETVFLDRNATKILHRPKRYNSGKLEEFIPGNLEKCSFEEAREVFENTEKTTEFWKQYV--------------------------------------DATCSIKNGRCKQFCKNKVVCSCTAGYRLAEDQKSCEPAVPFPCGRVSLTRAEIWDNVNRVVGGEDAARGQFPWQVLLHAFCGGSIVNEKWVVTAAHCIKPGKITVVAGEHNTPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLNSYVTPICIADREYTNIFYGYVSGWGKVFRSASILQYLKVPLVDRATCLRSTMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >OWJ99698.1 F9 [Cervus elaphus hippelaphus] --------------------------------------------------------------------------------------MCKDDINSYECWCQAGYEGKNCELDATCSIKNGRCKQFCKNKVVCSCTAGYRLAEDQKSCEPAVPFPCGRVSLTRAEIWDNVNRVVGGEDAARGQFPWQVLLHAFCGGSIVNEKWVVTAAHCIKPGKITVVAGEHNTPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLNSYVTPICIADREYTNIFYGYVSGWGKVFRSASILQYLKVPLVDRATCLRSTMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >OCT66091.1 hypothetical protein XELAEV_18042345mg [Xenopus laevis] SILIIYLLTSFCSAEPVFLSNSASSILVRQRRYNSGRLEEWVAGNLEKCNYEEAREVFENDDKTKEFWKQYIDGDQCLSKPCLNGGACKDDVSAYVCWCQQGYSGKNCELPVICSIMNGGCDHLCRKKVICSCASGYKLAENGKTCEAAVPYPCGEVSETRSLTTEKIVRIVGGTDSLKGEFPWQVHLVGFCGGSIINEKWIVTAAHCLLEGEFKVVAGEHNTSEGTEQYRKVAKAILYPTYNATMSRYNDDIALLELETPLNDYVRPVCIGSMDFTEKLFSMVSGWGDVRRPAIILQKLAVPFINRAACKRSSMFCAGYSEGGKDTCQGDSGGPHVTQYKNLWFLTGITSWGEKCAEKEKYGVYTKVSRFTDWIRTTTK >KAB0353393.1 hypothetical protein FD755_023904 [Muntiacus reevesi] GTFG----GGIMGAN----------------------LPPFIPG----------------TE--------------------------------------------------------------------------HILTRKLKSPE-----------LMRGKQWGE-VEMVGGETRRSA----QVLLHAFCGGSIVNEKWVVTAAHCIKPGKITVVAGEHNTPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLNSYVTPICIADREYTNIFYGYVSGWGKVFRSASILQYLKVPLVDRATCLRSTMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >XP_030252094.1 coagulation factor IX-like isoform X3 [Sparus aurata] SLSFLCLLGAPAPASPVFLSGAADGVLRRHKRHNTGIFEEVLEGDLEVCDLEEAREIFENDGNTMEFWARYVDGDQCKSSPCQNQGSCNDHLGYYTCSCPSGFTGRNCEIAKRCDVNNGGCMHFCEFGAKCSCAKGYKLLEDGRNCDPETEFPCGRTAFTRSLTIRSRKRIVGGEVVIPGEIPWQAALVLFCGGSVLSERWVVTAAHCLVEGNFFIRVGEHSVHEDTEQDLEVMEQHIHPRYNASVSLYNHDIALIYLKSPFSPTVRPICIGPKAFTEALPATVSGWGRTRFTADTLQKVKVPFTDRTECKSSSMFCAGYYDEAKDACQGDSGGPHANSIHDTWFLTGIVSWGEECAKDGKYGVYTRLSLYYRWIKHVTG >XP_015816844.1 PREDICTED: coagulation factor IX isoform X1 [Nothobranchius furzeri] FLIVIASFETKEENSGVFVTQVAHMVLPRQRRHNSGHVEEVFKANLEVCSFEEAREVFEDDEKTNEFWTLYVDGDQCKPQPCQNGGECVDGISSYTCWCKPNYSGKNCEITKLCSINNGGCLHFCVQRAACHCAAGYKLGTDKKSCEPLAQFSCGRVVLMMSELSPDERRIVGGNEAIPGEIPWQVTLMSFCGGSLLSELWVITAAHCLKDPYFFVRAGEHDVHEGPERDHEVVEQHVHPIYDYTVSRYNHDIALLKLATPLSNKRRPICLGPKDFIQTLSSLVSGWGRQQREANKLQKLSIPHVDRTLCKQSSMFCAGYPDGEKDSCQGDSGGPHATNYKGTWFLTGIVSWGEECARKGKYGIYTRVSRYYKWVSETTG >XP_023805491.1 uncharacterized protein LOC101163720 [Oryzias latipes] -LWRLCLFTLHLTT-HVFIDGAANQVLTRPRRANS-LFEEMKQGNLERCDKEEAREIFEDDQKTQEFWSKYFDGDSCLSKPCVNNGRCKDGIGTYSCYCLEGFKGHNCEIPQLCETKNGGCEHFCHRAVQCSCADGYYLAPNNKNCHSNNTFKCGAIVEVNST-LSTSVRIVNGEDCPPGECPWQALLLGFCGGTILSEHIILTAAHCMNQTYMYVKLGKFDMTEKFEATHAVATIISHSKYTPL--TYNNDIALIKLQNPFTKYILPACLPDQEFAEKVEGLVSGFGRLGAPSTILQRLSVPYVDRHVCMESTMFCAGYDKEAKDACQGDSGGPHVTRYHDTYFVTGVVSWGEGCARKGKYGIYTQVSKYIPWIRVATK >NP_032005.1 coagulation factor IX isoform 1 preproprotein [Mus musculus] ALITIFLLGYLLSTEAVFLDRNATKILTRPKRYNSGKLEEFVRGNLERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDISSYECWCQVGFEGRNCELDATCNIKNGRCKQFCKNKVICSCTEGYQLAEDQKSCEPTVPFPCGRASITRAEILNNVTRVVGGENAKPGQIPWQVILNAFCGGAIINEKWIVTAAHCLKPGKIEVVAGEYNIKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLNSYVTPICVANREYTNIFSGYVSGWGKVFRQASILQYLRVPLVDRATCLRSTMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >NP_113728.1 coagulation factor IX precursor [Rattus norvegicus] GLIPIFLLGYLLSTEAVFLDRNATKILTRPKRYNSGKLEEFVQGNLERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQAGFEGRNCELDATCSIKNGRCKQFCKNKIICSCTEGYQLAEDQKSCEPAVPFPCGRVSITRAEILDNLTRVVGGENAKPGQIPWQVILNAFCGGAIINEKWIVTAAHCLKPGKIEVVAGEHNIKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLNSYVTPICVANKEYTNIFSGYVSGWGKVFRQASILQYLRVPLVDRATCLRSTMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >NP_989674.1 coagulation factor IX precursor [Gallus gallus] LILSFCLLEAFLGAETVFIENEASTVLSRTRRGNSNRLEELIPGNLEKCSFEEAREVFENTEKTMEFWKIYIDGDQCNSNPCKNGAVCKDGVSSYECMCPPGYGGRNCEIDSTCATKNGGCEHFCRQKAVCSCASGYKLHEDGKSCKPAVPYPCGRITVTRTEALD-ITRVVGGYDSVKGQLPWQVHLVGFCGGSIINEKWVVTAAHCLEPGNVTAVAGEYNTDDHTEQRRQVVKILPYPTYNRTRNKHHNDIALLELDQPFNSYVTPICIGSRDFTNNLPGTVSGWGSMLRSAIVLQVLTVPFVDRVTCLKSTMFCAGYTAGGKDTCGGDSGGPYTNSIGETWFLTGVTSWGEECAKPGKYGIYTKVAKYVKWIRETTR >NP_001157475.1 coagulation factor IX [Sus scrofa] GLVSICLLGYLLSAETVFLDRNATKILHRPKRYNSGKLEEFVRGNLEKCSFEEAREVFENTEKTNEFWKQYVDGDQCEPNPCLNGGLCKDDINSYECWCQVGFEGKNCELDATCNIKNGRCKQFCKSKVLCSCTTGYRLAPDQKSCEPAVPFPCGRVSLTRAEILDSLIRIVGGENAKPGQFPWQVLLNAFCGGSIINEKWVVTAAHCIEPGKITVVAGEYNTTEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLNSYVTPICIADKEYTNIFSGYVSGWGRVFRSATILQYLKVPLVDRATCLRSTMFCAGFHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEKTK >NP_001003323.1 coagulation factor IX preproprotein [Canis lupus familiaris] GLVTVCLLGYLLSAEAVFLDRNATKILSRPKRYNSGKLEEFVRGNLEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNDGVCKDDINSYECWCRAGFEGKNCELDVTCNIKNGRCKQFCKNKVVCSCTTGYQLAEDQRSCEPAVPFPCGRVSRTRAEILDNVTRVVGGKDAKPGQFPWQVLLNAFCGGSIINEKWVVTAAHCIEPDKITIVAGEHNTREHTEQKRNVIRTILHHSYNATINKYNHDIALLELDEPLNSYVTPICIADREYSNIFSGYVSGWGRVFRSASILQYLKVPLVDRATCLRSTMFCAGFHEGGKDSCQGDSGGPHVTEVEGISFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >XP_004022354.1 coagulation factor IX [Ovis aries] GLVTICLLGYLLSAETVFLDRNATKILHRPKRYNSGKLEEFVRGNLEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGMCKDDINSYECWCQAGFEGKNCELDATCSIKNGRCKQFCKNKVVCSCTAGYRLAQDQKSCEPAVPFPCGRVSLTRAEIWDNVNRVVGGEDAARGQFPWQVLLHAFCGGSIVNEKWVVTAAHCIKPGKITVVAGEHNTPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLNSYVTPICIADREYTNIFYGYVSGWGKVFRSASILQYLKVPLVDRATCLRSTMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >NP_001129063.1 coagulation factor IX precursor [Pan troglodytes] GLITICLLGYLLSAETVFLDHNANKILNRPKRYNSGKLEEFVQGNLEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCEQFCKNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSLTRAEILDNITRVVGGEDAKPGQFPWQVVLNAFCGGSIVNEKWIVTAAHCVDTGKITVVAGEHNITEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLNSYVTPICIADKEYTNIFSGYVSGWGRVFRSALVLQYLRVPLVDRATCLRSTMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >NP_001009377.1 coagulation factor IX precursor [Felis catus] GLITICLLGYLLGADTVFLDHDATKVLSRPKRYNSGKLEEFVQGNLEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQTGFEGKNCELDVTCNIKNGRCKQFCKNKVVCSCTTGYQLAEDQKSCEPAVPFPCGRVSHTRAENVDNVTRIVGGKTAKPGQFPWQVLLKAFCGGSIINEKWVVTAAHCINPDEITVVAGEHNTTEHTEQKRNVIRTILHHSYNASVNKYSHDIALLELDEPLNSYVTPICVADREYTNTFYGYVSGWGKVFRPATILQYLKVPLVDRATCLRSTMFCAGFHEGGKDSCQGDSGGPHVTEVEGINFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >NP_001182654.1 coagulation factor IX [Oryctolagus cuniculus] GLITICLLGYLLSAETVFLDHNATKILNRAKRYNSGKLEEFVSGNLERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGSCKDDINAYECWCQYGFEGKNCELDSTCSIKNGRCEQFCRNKIICSCTEGYRLAENQKSCEPAVPFPCGRVSITRATIRGNVTRIVGGENAKPGQFPWQVLLNAFCGGSIINEKWVVTAAHCIKPDNITVVAGEYNITENTEQKRNVIRIIPYHKYNATINKYNHDIALLELDKPLNSYVTPICIANREYTNIFSGYVSGWGRVFRQASILQYLRVPFVDRATCLRSTMFCAGFDVGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAIKGKYGVYTRVSWYVNWIKEKTK >XP_002832230.2 coagulation factor IX isoform X1 [Pongo abelii] GLITICLLGYLLSAETVFLDHNANKILNRPKRYNSGKLEEFVQGNLEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCKQFCKNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSLTRAEILDNITRVVGGEDAKPGQFPWQVVLNAFCGGSIVNEKWIVTAAHCIETGKITVVAGEHNITEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLNSYVTPICIADKEYTNIFSGFVSGWGRVFRSASILQYLRVPLVDRATCLRSTMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >XP_010713519.1 LOW QUALITY PROTEIN: coagulation factor IX [Meleagris gallopavo] LILSFCLLEAFLGAEAVFIENEANTVLSRTRRGNSNRLEEFISGNLEKCSFEEAREVFENTEKTMEFWKIYIDGDQCNSNPCKNGAMCKDGVSSYECMCPPGYGGRNCEIDSTCATKNGGCEHFCRQKAVCSCASGYKLHEDGKSCKPEVPYPCGRITVTRTEVLD-ITRVVXGYDSVKGQLPWQVHLVGFCGGSIINEKWVVTAAHCLKPGNVTAVAGEYNTDDHTEQWRQVVKILPYPTYNRTRNKHHNDIALLELDQPFNSYVTPICIGSRDFTNNLPGTVSGWGSMLRSAVILQVLTVPFVDRVTCLKSTMFCAGYTAGGKDTCGGDSGGPYANSIGETWFLTGVTSWGEECAKPGKYGIYTKVAKYVKWIRETTR >XP_003812356.2 coagulation factor IX [Pan paniscus] GLITICLLGYLLSAETVFLDHNANKILNRPKRYNSGKLEEFVQGNLEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCEQFCKNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSLTRAEILDNITRVVGGEDAKPGQFPWQVVLNAFCGGSIVNEKWIVTAAHCVDTGKITVVAGEHNITEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLNSYVTPICIADKEYTNIFSGYVSGWGRVFRSALVLQYLRVPLVDRATCLRSTMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >XP_004064996.1 coagulation factor IX [Gorilla gorilla gorilla] GLITICLLGYLLSAETVFLDHNANKILNRPKRYNSGKLEEFVQGNLEKCSFEEAREVFENTERTTEFWKQYVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVTCNIKNGRCEQFCKNKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSLTRAEILDNITRVVGGEDAKPGQFPWQVVLNAFCGGSIVNEKWIVTAAHCVETGKITVVAGEHNITEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLNSYVTPICIADKEYTNIFSGYVSGWGRVFRSALILQYLRVPLVDRATCLRSTMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >XP_005500580.1 coagulation factor IX [Columba livia] LVFSICLLGACLGATTVFIENEANSILHRQKRANSNRLEEVIPGNLEKCSFEEAREVFENTEKTMEFWKTYIDGDQCDPNPCKNGAVCKDAVSSYVCWCPAGYEGRNCEIDFTCAIKNGGCKHFCRQKVVCSCAAGYRLHEDGKSCEPTVPYPCGRITLTRAIVLDNITRVVGGSDSMRGEVPWQVHLVGFCGASIINEKWVVTAAHCLKPGEIMAVAGEYNTDDKTEQWRKVVKILPHPTYNATINKHHNDIALLELDQPFNSYVTPICLGSRDFTNALMGTVSGWGR--SSATILQVLKVPFVDRPTCLKSTMFCAGYSAGGSDTCGGDSGGPYTTEIEGTWFLTGITSWGEECAKPGKYGIYTRVSKYVKWIKETTR >XP_005700488.1 PREDICTED: coagulation factor IX [Capra hircus] GLVTICLLGYLLSAETVFLDRNATKILHRPKRYNSGKLEEFVRGNLEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGMCKDDINSYECWCQAGFEGKNCELDATCSIKNGRCKQFCKNKVVCSCTAGYRLAQDQKSCEPAVPFPCGRVSLTRAEIWDNVNRVVGGEDAARGQFPWQVLLHAFCGGSIVNEKWIVTAAHCIKPGKITVVAGEHNTPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLNSYVTPICIADREYTNIFYGYVSGWGKVFRSASILQYLKVPLVDRATCLRSTMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >XP_006031120.3 coagulation factor IX [Alligator sinensis] LSVSVCLLGLFLQAESVFIDKQASSVLPRQKRFNSKRLEEVVAGNLEKCSYEEAREVFENEEKTMEFWKGYLDGDQCNPNPCKNGGSCQDELNSYVCWCLLGFEGRNCELDSTCATKNGGCKQFCRHKVVCSCAAGYTLHEDRKTCIPAVPFPCGRISITRAMATGSVTRVVGGTDSKKGEIPWQVHLRGFCGGSIVNERWIVTAAHCLEPGEITVVAGEHDTEDDTEQHRKVINIIPHPTYDAKVNKHHNDIALLELESPLNSYVTPICIASKDFTNNLMGTVSGWGSLLRPAQVLQVLKVPYVDRSTCLKSSMFCAGYPAGGKDTCTGDSGGPYATDIEGTWFLTGITSWGEDCAQKGKYGIYTRVSRYAKWIQNTTK >XP_006278300.1 PREDICTED: coagulation factor IX [Alligator mississippiensis] LSVSVCLLGLFLQAESVFIDNQASSVLPRQKRFNSKRLEEVVSGNLEKCSYEEAREVFENEEKTMEFWKGYLDGDQCNPNPCKNGGSCQDELNSYVCWCPLGFEGRNCELDSTCATKNGGCKQFCRHKVVCSCAAGYTLHEDRKTCIPAVPFPCGRISITRAMAAGNVTRVVGGTDSKKGEIPWQVHLRGFCGGSIVNERWIVTAAHCLVPGEITVVAGEHDTEDDTEQHRKVINIIPHPTYDAKINKHHNDIALLELESPLNSYVTPICIASKDFTNNLIGTVSGWGSLLRPAQVLQVLKVPYVDRSTCLKSSMFCAGYPAGGKDTCAGDSGGPYTTDIEGTWFLTGITSWGEDCAQKGKYGIYTRVSRYVKWIQNMTK >XP_020770402.1 coagulation factor IX [Odocoileus virginianus texanus] GLVTICLLGYLLSAETVFLDRNATKILHRPKRYNSGKLEEFIPGNLEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGMCKDDINSYECWCQAGYEGKNCELDATCSIKNGRCKQFCKNKVVCSCTAGYQLAEDQKSCEPAVPFPCGRVSLTRAEIWDNVNRVVGGEDAARGQFPWQVLLHAFCGGSIVNEKWVVTAAHCIKPGKITVVAGEHNTPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLNSYVTPICIADREYTNIFYGYVSGWGKVFRSASILQYLKVPLVDRATCLRSTMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK >XP_040179710.1 coagulation factor IX [Rana temporaria] YILIIFLLGYFCRAETVFLSASASGVLVRQKRYNSGGFEELSAGNLEKCTYEEAREVFENDEKTSEFWKQYVDGDQCISNPCLNGGVCKDDVSAYVCWCEHGYRGKNCEFPVTCTINNGGCQQMCRKKVTCSCASGYKLGEDGQTCQEIVQYPCGRVSETRTISTENIVRIVGGTDSLKGEFPWQVHFIGFCGGSIVNEKWIVTAAHCFITISFSVVAGEHNTKEGTEQYMEVTRIINHPSYNVSKNKYNNDIALVELEKPLNDYARPICIGHKDFTDRLHSWVTGWGNLRRPTVKLQKLAVPFVDRATCKRSSMFCAGFADEEKDACQGDSGGPHATDFRNTWFLTGITSWGDKCAQKDRYGVYTRVSRFTDWILSTTK
PhyML tree of selected proteins (XP_023805491_1_uncharacterized_protein_LOC101163720__Oryzias_latipes_:0.87330197,((((((XP_002832230_2_coagulation_factor_IX_isoform_X1__Pongo_abelii_:0.0026418,(XP_004064996_1_coagulation_factor_IX__Gorilla_gorilla_gorilla_:0.00000001,((NP_001129063_1_coagulation_factor_IX_precursor__Pan_troglodytes_:0.00000001,XP_003812356_2_coagulation_factor_IX__Pan_paniscus_:0.00000001):0.0027926,sp_P00740_FA9_HUMAN_Coagulation_factor_IX_OS_Homo_sapiens_OX_9606_GN_F9_PE_1_SV_2:0.00000001):0.00279228):0.00861597):0.04386511,(NP_001182654_1_coagulation_factor_IX__Oryctolagus_cuniculus_:0.08201767,(NP_113728_1_coagulation_factor_IX_precursor__Rattus_norvegicus_:0.01303984,NP_032005_1_coagulation_factor_IX_isoform_1_preproprotein__Mus_musculus_:0.0239392):0.07084504):0.03289304):0.01766019,((NP_001157475_1_coagulation_factor_IX__Sus_scrofa_:0.05677976,(sp_P00741_FA9_BOVIN_Coagulation_factor_IX_OS_Bos_taurus_OX_9913_GN_F9_PE_1_SV_2:0.01026819,((XP_004022354_1_coagulation_factor_IX__Ovis_aries_:0.00000002,XP_005700488_1_PREDICTED__coagulation_factor_IX__Capra_hircus_:0.00283014):0.00281009,(KAF4026817_1_hypothetical_protein_G4228_019179__Cervus_hanglu_yarkandensis_:0.00000001,((KAB0353393_1_hypothetical_protein_FD755_023904__Muntiacus_reevesi_:0.19037532,XP_020770402_1_coagulation_factor_IX__Odocoileus_virginianus_texanus_:0.00089381):0.00198242,(XP_043315927_1_coagulation_factor_IX__Cervus_canadensis_:0.00000001,(KAB0345414_1_hypothetical_protein_FD754_022340__Muntiacus_muntjak_:0.02751929,OWJ99698_1_F9__Cervus_elaphus_hippelaphus_:0.00000002):0.00000001):0.00000001):0.00000001):0.00862165):0.00787603):0.04520693):0.0129944,(NP_001009377_1_coagulation_factor_IX_precursor__Felis_catus_:0.07744734,NP_001003323_1_coagulation_factor_IX_preproprotein__Canis_lupus_familiaris_:0.0283449):0.02491674):0.0075136):0.27136431,((XP_005500580_1_coagulation_factor_IX__Columba_livia_:0.06559936,(XP_010713519_1_LOW_QUALITY_PROTEIN__coagulation_factor_IX__Meleagris_gallopavo_:0.02000701,NP_989674_1_coagulation_factor_IX_precursor__Gallus_gallus_:0.01479596):0.17483146):0.10923154,(XP_006278300_1_PREDICTED__coagulation_factor_IX__Alligator_mississippiensis_:0.01005451,XP_006031120_3_coagulation_factor_IX__Alligator_sinensis_:0.02442083):0.20891327):0.11794045):0.16400339,(OCT66091_1_hypothetical_protein_XELAEV_18042345mg__Xenopus_laevis_:0.15974356,XP_040179710_1_coagulation_factor_IX__Rana_temporaria_:0.2692403):0.15838174):0.20925958,(XP_015816844_1_PREDICTED__coagulation_factor_IX_isoform_X1__Nothobranchius_furzeri_:0.47444535,(tr_Q1RLV2_Q1RLV2_DANRE_Christmas_factor_OS_Danio_rerio_OX_7955_GN_f9b_PE_2_SV_1:0.43223065,(tr_E7F301_E7F301_DANRE_Christmas_factor_OS_Danio_rerio_OX_7955_GN_f9a_PE_4_SV_2:0.42065514,XP_030252094_1_coagulation_factor_IX_like_isoform_X3__Sparus_aurata_:0.37560853):0.17455816):0.10037882):0.25982324):0.15812968,((((XP_038051917_1_trypsin_like__Patiria_miniata_:0.85979126,NP_501379_2_Serine_protease_svh_1__Caenorhabditis_elegans_:1.86239986):0.28301678,(XP_016769420_1_trypsin_1__Apis_mellifera_:0.57848188,NP_611611_1_tracheal_prostasin__Drosophila_melanogaster_:0.71454959):0.98140513):0.14658692,(XP_030828169_1_uncharacterized_protein_LOC752081__Strongylocentrotus_purpuratus_:1.77564053,CAE1319957_1_F2__Sepia_pharaonis_:2.01560433):0.48552744):0.08978153,(XP_031561359_1_atrial_natriuretic_peptide_converting_enzyme_like_isoform_X3__Actinia_tenebrosa_:1.2036575,XP_039268100_1_A_disintegrin_and_metalloproteinase_with_thrombospondin_motifs_adt_1_like__Styela_clava_:1.36792867):0.23859553):0.42883744);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)