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PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0066 | P08582 | Melanotransferrin | MELTF | CD228, MAP97, MFI2, MTF1, MTf | Homo_sapiens | Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. |
Domains | Gene Ontology |
PF00405 (2_Transferrin) |
GO:0005506 (enables) iron ion binding
GO:0005515 (enables) protein binding GO:0046872 (enables) metal ion binding GO:0006811 (involved in) ion transport GO:0006826 (involved in) iron ion transport GO:0010756 (involved in) positive regulation of plasminogen activation GO:0055072 (involved in) iron ion homeostasis GO:0090091 (involved in) positive regulation of extracellular matrix disassembly GO:1900025 (involved in) negative regulation of substrate adhesion-dependent cell spreading GO:0005769 (is active in) early endosome GO:0055037 (is active in) recycling endosome GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005788 (located in) endoplasmic reticulum lumen GO:0005886 (located in) plasma membrane GO:0009986 (located in) cell surface GO:0016020 (located in) membrane GO:0031225 (located in) anchored component of membrane GO:0046658 (located in) anchored component of plasma membrane GO:0070062 (located in) extracellular exosome |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |