PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0053 | P55268 | Laminin subunit beta-2 | LAMB2 | LAMS, NPHS5, PIERS | Homo_sapiens | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
Domains | Gene Ontology |
PF00053 (13_Laminin_EGF) PF00055 (Laminin_N) |
GO:0005178 (enables) integrin binding
GO:0005198 (enables) structural molecule activity GO:0005201 (enables) extracellular matrix structural constituent GO:0005515 (enables) protein binding GO:0000904 (involved in) cell morphogenesis involved in differentiation GO:0007155 (involved in) cell adhesion GO:0007411 (involved in) axon guidance GO:0007528 (involved in) neuromuscular junction development GO:0007601 (involved in) visual perception GO:0009887 (involved in) animal organ morphogenesis GO:0009888 (involved in) tissue development GO:0014002 (involved in) astrocyte development GO:0014044 (involved in) Schwann cell development GO:0016477 (involved in) cell migration GO:0031175 (involved in) neuron projection development GO:0034446 (involved in) substrate adhesion-dependent cell spreading GO:0048677 (involved in) axon extension involved in regeneration GO:0050808 (involved in) synapse organization GO:0060041 (involved in) retina development in camera-type eye GO:0070831 (involved in) basement membrane assembly GO:0072249 (involved in) metanephric glomerular visceral epithelial cell development GO:0072274 (involved in) metanephric glomerular basement membrane development GO:0005576 (located in) extracellular region GO:0005604 (located in) basement membrane GO:0005788 (located in) endoplasmic reticulum lumen GO:0031594 (located in) neuromuscular junction GO:0043083 (located in) synaptic cleft GO:0045202 (located in) synapse GO:0070062 (located in) extracellular exosome GO:0005608 (part of) laminin-3 complex GO:0043256 (part of) laminin complex GO:0043260 (part of) laminin-11 complex GO:0062023 (part of) collagen-containing extracellular matrix |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |