PB0050

DATABASE

Click here to access PB0050 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0050	Q15113	Procollagen C-endopeptidase enhancer 1	PCOLCE	PCPE, PCPE-1, PCPE1	Homo_sapiens	C-terminal processed part of PCPE (CT-PCPE) may have an metalloproteinase inhibitory activity.

Domains

Gene Ontology

PF00431 (2_CUB) PF01759 (NTR)

GO:0062023 (colocalizes with) collagen-containing extracellular matrix GO:0005201 (enables) extracellular matrix structural constituent GO:0005515 (enables) protein binding GO:0005518 (enables) collagen binding GO:0008201 (enables) heparin binding GO:0016504 (enables) peptidase activator activity GO:0007275 (involved in) multicellular organism development GO:0010952 (involved in) positive regulation of peptidase activity GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0070062 (located in) extracellular exosome

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|Q15113|PCOC1_HUMAN Procollagen C-endopeptidase enhancer 1 OS=Homo sapiens OX=9606 GN=PCOLCE PE=1 SV=2 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPPN KECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPL VAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY PPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAV PGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTEPKVKLPPKS QPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAVTVSL IGAYKTGGLDLPSPPTGASLKFYVPCKQCPPMKKGVSYLLMGQVEENRGPVLPPESFVVL HRPNQDQILTNLSKRKCPSQPVRAAASQD >tr|B3DJG2|B3DJG2_DANRE Procollagen C-endopeptidase enhancer b OS=Danio rerio OX=7955 GN=pcolceb PE=2 SV=1 MWAAVRVCHLGLLFLGLGWVHGQSQTNFTRPVFLCGGHLVTDSGFVASEGFPSHYKANSK CTWYITVPEGHVVMLQFRIFDLEADPTCRYDYVDVYNGHSYTVQKLGRFCGTFRPGALIS TSNTMMLEMASDSSTGGRGFLAYFSGGKPHVDEHQFCGGRLTKPQGSVKTPNWPESDYPA GISCSWHISVESNMVIEVKFEKLDLELDTYCRYDYVALFNGGETDDSRRIGKFCGDTVPD AVVTNGNELLVHFVSDLSVTAAGFMAHYRSVPRGSRTPTADLDTVHGPRVNTSPTKPTVP PQRVKPKPTPKPPSRPFKPVPPRPTPKTRSNPAAKPKPVRPTPPTRRSGSKITPKPAVKV TAKPATKPTPKPAIRPQPKPTSTTAKQEVKPGVKPTAKTISKPGNRTTSRTASAGNPLCS LPCKRIGTMVTRFCPSHFVLTGKVTSLSPGSQGSAEVEVSVIKVYKAGRLQLRKRGPSTS ATLTATCSKCPALRKGVNYVLMGHVNDDGLGILNPSSFALQHKAVHDRALANLAKKAC >tr|F1QUX0|F1QUX0_DANRE Procollagen C-endopeptidase enhancer a OS=Danio rerio OX=7955 GN=pcolcea PE=4 SV=1 MRSSVLLDMEHLTVVWSLWLLLSLSFGGVLCQTTNYTRPVFNCGGDLVGDSGFVGSEGFP SFYKPNSKCTWYITVPEGNVVMLSFRIFDLEADPLCRYDYVDVYNGHSNMVQKLGRFCGT FRPGALISTSNTMMVEMVSDSGTGGRGFVAYFNGGKPHVDEHQFCGGKLTKSQGTIKTPN WPEKNYPPGISCSWLITVEPEMVIEVKFDKFDLESDTYCRFDYVAFFNGGEKDDSRRIGK YCGYTAPQNIVTNSNVLLVQFVSDLSVTSDGFMASYTSIPRGLHSPSAGGDVVSGPRVSS TPTKPKIIPAKPVVTTEAITTTTTTTTEAPEQPKPRPKPVRPIKPVKPPVRKPEPERPRP ATETNPLCAKACKRDGTIKTSFCASEFVITGTLTALTAGPRGSMQGTVSLIKAYKTGRLT ITQAGETMSVKLMMPCKKCPLLRRGQNYILMGEVDDEGRGVLNPGTFTALYKAPHHKMLT NINNQPC
Selected proteins from model organisms >sp|Q15113|PCOC1_HUMAN Procollagen C-endopeptidase enhancer 1 OS=Homo sapiens OX=9606 GN=PCOLCE PE=1 SV=2 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPPN KECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPL VAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY PPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAV PGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTEPKVKLPPKS QPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAVTVSL IGAYKTGGLDLPSPPTGASLKFYVPCKQCPPMKKGVSYLLMGQVEENRGPVLPPESFVVL HRPNQDQILTNLSKRKCPSQPVRAAASQD >tr|B3DJG2|B3DJG2_DANRE Procollagen C-endopeptidase enhancer b OS=Danio rerio OX=7955 GN=pcolceb PE=2 SV=1 MWAAVRVCHLGLLFLGLGWVHGQSQTNFTRPVFLCGGHLVTDSGFVASEGFPSHYKANSK CTWYITVPEGHVVMLQFRIFDLEADPTCRYDYVDVYNGHSYTVQKLGRFCGTFRPGALIS TSNTMMLEMASDSSTGGRGFLAYFSGGKPHVDEHQFCGGRLTKPQGSVKTPNWPESDYPA GISCSWHISVESNMVIEVKFEKLDLELDTYCRYDYVALFNGGETDDSRRIGKFCGDTVPD AVVTNGNELLVHFVSDLSVTAAGFMAHYRSVPRGSRTPTADLDTVHGPRVNTSPTKPTVP PQRVKPKPTPKPPSRPFKPVPPRPTPKTRSNPAAKPKPVRPTPPTRRSGSKITPKPAVKV TAKPATKPTPKPAIRPQPKPTSTTAKQEVKPGVKPTAKTISKPGNRTTSRTASAGNPLCS LPCKRIGTMVTRFCPSHFVLTGKVTSLSPGSQGSAEVEVSVIKVYKAGRLQLRKRGPSTS ATLTATCSKCPALRKGVNYVLMGHVNDDGLGILNPSSFALQHKAVHDRALANLAKKAC >tr|F1QUX0|F1QUX0_DANRE Procollagen C-endopeptidase enhancer a OS=Danio rerio OX=7955 GN=pcolcea PE=4 SV=1 MRSSVLLDMEHLTVVWSLWLLLSLSFGGVLCQTTNYTRPVFNCGGDLVGDSGFVGSEGFP SFYKPNSKCTWYITVPEGNVVMLSFRIFDLEADPLCRYDYVDVYNGHSNMVQKLGRFCGT FRPGALISTSNTMMVEMVSDSGTGGRGFVAYFNGGKPHVDEHQFCGGKLTKSQGTIKTPN WPEKNYPPGISCSWLITVEPEMVIEVKFDKFDLESDTYCRFDYVAFFNGGEKDDSRRIGK YCGYTAPQNIVTNSNVLLVQFVSDLSVTSDGFMASYTSIPRGLHSPSAGGDVVSGPRVSS TPTKPKIIPAKPVVTTEAITTTTTTTTEAPEQPKPRPKPVRPIKPVKPPVRKPEPERPRP ATETNPLCAKACKRDGTIKTSFCASEFVITGTLTALTAGPRGSMQGTVSLIKAYKTGRLT ITQAGETMSVKLMMPCKKCPLLRRGQNYILMGEVDDEGRGVLNPGTFTALYKAPHHKMLT NINNQPC >NP_032814.2 procollagen C-endopeptidase enhancer 1 precursor [Mus musculus] MLPAALTSFLGPFLLAWVLPLARGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPNKKCIWTITVPE GQTVSLSFRVFDMELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPVVAPGNQVTLRMTTDEGTGGRG FLLWYSGRATSGTEHQFCGGRMEKAQGTLTTPNWPESDYPPGISCSWHIIAPSNQVIMLTFGKFDVEPDT YCRYDSVSVFNGAVSDDSKRLGKFCGDKAPSPISSEGNELLVQFVSDLSVTADGFSASYRTLPRDAVEKE SALSPGEDVQRGPQSRSDPKTGTGPKVKPPTKPKSQPAETPEASPATQATPVAPAAPSITCPKQYKRSGT LQSNFCSSSLVVTGTVKTMVRGPGEGLTVTVSLLGVYKTGGLDLPSPPSGTSLKLYVPCRQMPPMKKGAS YLLMGQVEENRGPILPPESFVVLYRSNQDQILNNLSKRKCPSQPRTAA >KAB0349382.1 hypothetical protein FD754_014239 [Muntiacus muntjak] MLPAATASLLGPLLTAWALLLPFTHGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSF RVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFC GGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDT VPGSITSEGNELLVQFVSDLSVTADGFSATYRTQPRGATEGGPGEVGPGPKPGAGPKVKPEVPPEEKPKAEPKAEATPVG PDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQCP PMKKGISYLLMGQVDKNRGPILPPESFVVLHRPTQHQILTNLGRKCPSKPV >KAB0384410.1 hypothetical protein FD755_006327 [Muntiacus reevesi] MLPAATASLLGPLLTAWALLLPFTHGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSF RVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFC GGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDT VPGSITSEGNELLVQFVSDLSVTADGFSATYRTQPRGATEGGPGEIGPGPKPGAGPKVKPEVPPEEKPKAEPKAEATPVG PDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQCP PMKKGISYLLMGQVDKNRGPILPPESFVVLHRPTQHQILTNLGRKCPSKPV >XP_043310674.1 procollagen C-endopeptidase enhancer 1 isoform X2 [Cervus canadensis] MLPAATASLLGPLLTAWALLLPFTHGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSF RVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFC GGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDT VPGSITSEGNELLVQFVSDLSVTADGFSATYRTQPRGATEGGPGEVGPGPKPGAGPKVKPEVPPEEKPKAAPKAEATPVG PDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKAGGLDLPAPPTDTLLKFYVPCKQCP PMKKGISYLLMGQVDKNRGPILPPESFVVLHRPTQHQILTNLGRKCPSKPV >OWK11217.1 PCOLCE [Cervus elaphus hippelaphus] MPGWAGNGFVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFS ATYRTQPRGATEGGPGEVGPGPKPGAGPKVKPEVPPEEKPKAAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLV VTGMIKSMVRGPGEGLTATVNVTGVYKAGGLDLPAPPTDTLLKFYVPCKQCPPMKKVYPTEVLFGLAEATSDPLGLPPPS PWLPAHPHHLLASPALPHAGLTSLLFPRPVFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSFRVFDL EQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLE KAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSI TSEGNELLVQFVSDLSVTADGFSATYRTQPRGATEGGPGEVGPGPKPGAGPKVKPEVPPEEKPKAAPKAEATPVGPDAPS VTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKAGGLDLPAPPTDTLLKFYVPCKQCPPMKKG ISYLLMGQVDKNRGPILPPESFVVLHRPTQHQILTNLGRKCPSKPV >KAF4015881.1 hypothetical protein G4228_007241 [Cervus hanglu yarkandensis] MLPASTASLLGPLLTAWALLLPFTHGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSF RVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFC GGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDT VPGSITSEGNELLVQFVSDLSVTADGFSATYRTQPRGATEGGPGEVGPGPKPGAGPKVKPEVPPEEKPKAAPKAEATPVG PDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKAGGLDLPSPPTDTLLKFYVPCKQCP PMKKVFRADQRSGPRQLLTLYNPTGAVLRFRVLCTAPAKYTVFDAEGYVKPQSCIDIVIRHVAPNPRHYNVQDRFRIELS EEGTEGRVVGRKDITSVLRAPAYPLELQGQSDPTPHAEPHSWTAPSAAQPFPENPHPQLATSSFLLFLLMGTISVAFLLL PLQDELGSQLPQMFHVSLGQKLVAAYVLGEPSGSRPSKRRMGAGKRVYRAGRLHTQPCSFFLPSPGLLTMVFLRT >NP_001082711.1 uncharacterized protein LOC398671 precursor [Xenopus laevis] MGRTLLLCLSLVLGLSRARNSDTNNYTRPVFLCGGDITGDSGFIGSEGFPNYYPPNKKCVWNITVPDGHVVMLTFRLLDM EADPSCRYDYLNIYNGHFETGQRLARVCGTFRPGALLSTGPQMMLEMVTDDGTAGRGFLAWYSAGSTQPSESQLCGGKLE KPQGSINTPNWPENNYPSGISCSWHIVAPKEKVVELSFGKFDVEGDSYCRFDYLAVFNGGETDNTRLIGKFCGDSSPKTI YSDGNEMLVQFVSDLSVTADGFAVNYRMRDASEVPKTTPTSTSAPEKKAPLDTKLSNKPSVKLETIPEPKTKPTKLPKSP DTDSSSAVKCPQKCRKTGTLGSHYCANQFVVTGTVNSLTQGDSEKSLLATVTIIKTFKVEGLSIQESGKTMSIKVINECP KCPILKKGSSYLFMGEVNAEGQGRIVPESFVIAHKAAQHQILTAISKKPC >XP_021147809.1 procollagen C-endopeptidase enhancer 2 [Columba livia] MRCADTPLCPGGTRGCSTAPYTIFPIILRPTFACGGVVSGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLSFRYLD LESDNLCRYDFVDIYNGHANGQRIGRFCGTVKPGALISNSNKMLVQMTSDANTAGSGFIAKFSAAEPHERGDQYCGGRLE KPSGSFQTPNWPERDYPAGVTCSWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPI LSERNELLIQFLSDLSLTADGFIGHYKFRPKKLPATTVPPNTTTLPATSTVKPTVALCQQKCKRSGTIESNYCSSNFVIT GTVITAVTRAGSLHATISIINVYKEGNLAIQQAGKNMSAKIIVVCKQCPLIRRGLNYIIMGQVEEDGRGKVFPNSFVMSF KTKNSKILNALKNKTCYN >XP_015816628.1 PREDICTED: procollagen C-endopeptidase enhancer 2-like [Nothobranchius furzeri] MMSPCCIWGLLLFLSLTSGWTKAQQTNNTRPVFYCGGDLVAESGFVGSEGFPNFYKPNSKCIWRITVPEGNVVTLSFRIF DLEADSQCRYDYLEVYNGHSNGVQKLGRFCGTFRPGALISSTNTMMLEMRSDGETQGRGFVAYFSGAKPYVNDEQFCGGK MTKSQGEIKTPNWPDNKYPPGISCSWIITVEPNQVIQVKFEKFILEADTYCRFDYVLFFNGGERDDSRLIGRYCGDQTPE PIITSGNMLLVHFVSDFSVPSDGFFAYYTSIPRGSQSATVESGARTVSVPSVPVIKPAEPERPVVLRITTTTIPTTSTIP TTTKARVSRPNGKRPVLQNPLCAKACKRTGTIKTAFCSSEFVITGKVMSLTPGPRGTLHIKVSLIKAYKAGRLTITQVGE TMAVKLVSQCKKCPLLRRGANHIIMGQVDEEGRGTLAPGAFTAPYKTQQDKLLMNINNQPC >XP_040535317.1 procollagen C-endopeptidase enhancer 2 isoform X2 [Gallus gallus] MKSLSEVTENCKNSSFVLRPTFTCGGVVSGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLSFRYLDLESDNLCRYD FVDIYSGHANGQRIGRFCGTVKPGALVSSSNKMLVQMTSDANTAGNGFIAKFSAAEPHERGDQYCGGRLEKPSGSFQTPN WPERDYPAGVTCSWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPIVSEKNELFIQ FLSDLSLTADGFIGHYKFRPKKLPTTTVPPTTTTVPATSIPKPTVALCQQKCKRSGTPESNYCSSNFVITGTVISTTTRA GSLHATISIINVYKEGNLAIQQAGKNMSAKIIVVCKQCPLLRRGLNYIIMGQVEEDGRGKIFPNSFVMSFKTKNQKILNS LKNKTCYN >XP_031410927.1 procollagen C-endopeptidase enhancer 2 [Meleagris gallopavo] MPGARSPRDTEPLSKNRAQRVTTLGIKDNSLLRALLTAAVRSGEHRVPHHQTLPPRYSPAAAASSLSTATCRPRDEAGRA GGQWPTFTCGGVVSGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLSFRYLDLESDNLCRYDFVDIYSGHTNGQRIG RFCGTVKPGALVSSSNKMLVQMTSDANTAGSGFIAKFSAAEPHERGDQYCGGRLEKPSGSFQTPNWPERDYPAGVTCSWH IVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPILSEKNELFIQFLSDLSLTADGFIGH YKFRPKKLPTTTVPPTTTTIPATSVSKPTVALCQQKCKRSGTLESNYCSSNFVITGTVISTTTRAGSLHATISIINVYKE GNLAIQQAGKNMSAKIIVICKQCPLIRRGLNYIIMGQVEEDGRGKIFPNSFVMSFKTKNQKILNALKNKTCYN >XP_030253492.1 procollagen C-endopeptidase enhancer 2 isoform X2 [Sparus aurata] MPFMPRGENRRTMWRTCSVFCAWSLLFLAEVCAQSQRRPTFTCGGNITGESGVIGSQGYPGVYPPNTKCVWRITVPEGKV VVLSFRSIDLESDNLCRYDYVDVYSGHVSGQRLGRFCGTFKPGALVSTGNKMLMQMVSDANTAGSGFLAVFSAAHPHERG DQYCGGRLDRPSGTFKTPNWPEKDYPAGVTCSWHIVAPKNQIIEVKFEKFDVERDNYCRYDHVSIFNGAEINDAKRIGKY CGDSPPAPVFSDGNQLLIQFLSDLSLTADGFIGHYKFRPKKFPTTTIPPTTTTQPLTTRPIPLKYSVALCQQKCKRRGTL ESNYCSSNFVITGTVITAVMRGGSMFATVSIINVYKEGSLAIQQAGKTMSTKIIILCKKCPFIRRGLNYVFMGQVDEDGK GKIAPHHFVMAFKTKNQKGLNVLKDKRC >XP_004081148.3 procollagen C-endopeptidase enhancer 2 [Oryzias latipes] MPFMSRCERRRCLLPAMWRACCLFCAWSLLLLTQVCAQSERRPIFTCGGNITGESGVIGSQGYPGVYPPNTKCVWRITVP EGKVVVLSFRTIDLENDNLCRYDYVDVYSGHISAQRLGRFCGTFKPGSLVSTGNKMLLQMVSDANTAGSGFLAVFSAAHP HERGDQYCGGRLVKPNGTFKTPNWPEKDYPAGVTCSWHIVAPKNQIIEVKFEKFDVERDNYCRYDHVSIFNGAEINDARR IGKYCGDSPPAPVFSEGNQVLIQFLSDLSLTADGFIGHYKFRPKKFSITTAPPPTTTHPVTTRPIPLKYSVALCQQKCKR RGTLHSNYCSSNFVITGTVITAMMKGGSMYATVSIINVYKEGNLAIQQAGKTMSTKIIILCKKCPFIRRGLNYIFMGQVD EEGRGKIAPQHFVMAFKTKNQKGLNVLKNKQC >NP_062110.1 procollagen C-endopeptidase enhancer 1 precursor [Rattus norvegicus] MLPAALTSLLGPFLLAWVLPLARGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPNKKCIWTITVPE GQTVSLSFRVFDMELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPVVAPGNQVTLRMTTDEGTGGRG FLLWYSGRATSGTEHQFCGGRMEKAQGTLTTPNWPESDYPPGISCSWHIIAPSNQVIMLTFGKFDVEPDT YCRYDSVSVFNGAVSDDSKRLGKFCGDKAPSPISSEGNELLVQFVSDLSVTADGFSASYRTLPRDAVEKE SAPSPGEDAQHGPQSRSDPKTGTGPKVKPPSKPKVQPVEKPEGSPATQATPVAPDAPSITCPKQYKRSGT LQSNFCSSSLVVTGTVKAMVRGPGEGLTVTVSLLGVYKTGDLDLPSPASGTSLKFYVPCKQMPPMKKGAS YLLMGQVEENRGPILPPESFVVLYRPNQDQILSNLSKRKCPSQPRPDA >XP_016801667.1 procollagen C-endopeptidase enhancer 1 [Pan troglodytes] MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPPNKECIWTITVP EGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVALRMTTDEGTGGR GFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPD TYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKE GQGPGPKPGTEPKVKLPPKSQPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREP GEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQCPPMKKGVSYLLMGQVEENRGPVLPPESFVVL HRPNQDQILTNLSKRKCPSQPVRAAASQD >XP_038394384.1 procollagen C-endopeptidase enhancer 1 isoform X1 [Canis lupus familiaris] MLPAATASLLGPLLTAWALLPFTQGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVP EGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTADEGTGGR GFLLWYSGRATSGTGPPPGARRKWVTDPRVEWAAWGYWDEHQFCGGRLEKAQGTLTTPNWPESDYPPGIS CSWHIIAPPDQVISLTFGKFDLEPDTYCRYDSVSVFNGAVSDDAKRLGKFCGDTAPGPISSEGNELLVQF VSDLSVTADGFSASYKTLPRGAAAEGQARSPGEDARSGASLPKPGPPPVEKPKASSEAQATPEAPNVPNV SCPKQCRRTGTLQSNFCSSSLVVTATVKSMVRGPGEGLTVTVSLIGAYKTGGLDLPSPITDTPLKFYVPC KQCPPMKKGASYLMMGQVEENRGPILPAESFVVLYRPNQDQILTNLSKRKCPSQPGRAAGSQA >NP_001039353.1 procollagen C-endopeptidase enhancer 1 precursor [Bos taurus] MLPAATASLLGPLLTAWALLLPFTHGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITV PKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPVVASGNQVTLRMRSDEGTGG RGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEP DSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSASYRTQPRGATE GVPGEVGLGPKPGAGPKVKPEVPPEEKSKAAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVT GMIKSMVRGPGEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQCPPMKKGISYLLMGQVDKNRGP ILPPESFVVLHRPTQHQILTNLSRKCPSKPV >XP_017198071.1 PREDICTED: procollagen C-endopeptidase enhancer 1 [Oryctolagus cuniculus] MLPAATASLLGPLLTAWALLPLAQGQTPNYTRPVFLCGGDVTGDSGYVASEGFPNLYPPNKECIWTITVP EGQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTADEGTGGR GFLLWYSGRATSGTGPPPGARRKWVTDPRVEWAAWGYWDEHQFCGGRMEKEQGTLTTPNWPESDYPPGIS CSWHIIAPPDQVIALTFGKFDLEPDTYCRYNSVSVFNGAVSDDAKRLGKFCGDTAPGPISSEGNELLVQF VSDLSVTADGFSASYRILPRGTAAQGPAQAPGEDARPGPPLVDSGSKPGVGPKVKPPTKPRVQPAGKPEA PPEAKTPPQDPDVPSIPCPKQCQRTGTMQSNFCTSNLVVTGTVKSIVRGPGEGLWVTVSLIGAYKTGGLE LPSPPTDASLKFYVPCKHCRPLKKGASYLLMGQVKENGVPVLPPDSFVVLYRPTQHQILTNLSKRKCPSQ PAESQV >XP_009240915.1 procollagen C-endopeptidase enhancer 1 isoform X1 [Pongo abelii] MCPRPREVPGHATVPPSPLPAPLASPHAHTPKAAPSGADYPAAAATAAAALQNSAAASVLRTPAPFPQAM LPAATASLLGPLLTAWALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPPNKECIWTITVPE GQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTADEGTGGRG FLLWYSGRATSGTGPPPGARRKWVTDPRVEWAAWGYWDEHQFCGGRLEKAQGTLTTPNWPESDYPPGISC SWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFV SDLSVTADGFSASYKTLPRGTAKGQGPSPKPGTEPKVKLPPKSQPPEKTEETPSAPDAPTCPKQCRRTGT LQSNFCASSLVVTATVKSMVREPGEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQCPPMKKGVS YLLMGQVEENRGPVLPPESFVVLHRPNQDQILTNLSKRKCPSQPVRAAASQD >XP_003354522.1 procollagen C-endopeptidase enhancer 1 [Sus scrofa] MLPAATASLLGPLLTAWALLPFAQGQTPNYTRPVFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVP ESQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGR GFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD SYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLPRGATEK APAQSPGEDARPSPPLLGPGPKPGAGPKVKPELPPEEKPKAAPKAEATPAGSDGPSVPCPKQCRRTGTLQ SNFCNSNLVVTATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTDTSLKFYAPCKQCPPMKKGTSYL MMGQVDENRGPILPPESFVVLYRPNQDQILTNLAKRRCPSQPVQAAESQA >XP_003812960.2 procollagen C-endopeptidase enhancer 1 [Pan paniscus] MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPPNKECIWTITVP EGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVALRMTTDEGTGGR GFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPD TYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKE GQGPGPKPGTEPKVKLPPKSQPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREP GEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQCPPMKKGVSYLLMGQVEENRGPVLPPESFVVL HRPNQDQILTNLSKRKCPSQPVRAAASQD >XP_006942048.3 procollagen C-endopeptidase enhancer 1 isoform X1 [Felis catus] MCPRPREAPGLTTVPTALSLSRLPHRPPRWPVPTPTHPRLPHLALIIPAAAAAAAKLSCCLVSRTPAPLP PAMLPAATASLLGPLLTAWALLPFAQGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPNKECIWTIT VPEGQTVSLSFRVFDFELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTADEGTG GRGFLLWYSGRATSGTGPPPGARRKWVTDPRVEWAAWGYWDEHQFCGGRLEKAQGTLTTPNWPESDYPPG ISCSWHIIAPPDQVISLTFGKFDLEPDTYCRYDSVSVFNGAASDDAKRLGKFCGDTAPGTISSEGNELLV QFVSDLSVTADGFSASYKTLPRGAAKEAQAQSAGEDARSGTPILSPGPKPGLPSEEKPKASSEAQATPGG PDVPSVPCPKQCRRTGTLQSNFCTSNLVVTATVKSMVRGPGEGLTVTVSLIGAYKTGGLDLPSPLTDTPL KFYVPCKQCPPMKKGVSYLMMGQVEENRGPTLPPESFVVLYRSNQDQILTNLSKRKCPSQPVRAAGSQA >XP_004021061.1 procollagen C-endopeptidase enhancer 1 [Ovis aries] MLPAATASFLGPLLTAWALLLPFTHGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITV PKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGG RGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEP DSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSASYRIQPRGATE EGPGEVGPGPKPGAGPKVKPEVPPEEKPKAAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVT GMIKSMVRGPGEGLTATVNVTGVYKTGGLDLPSPPTDSLLKFYVPCKQCPPMKKGISYLLMGQMDKNRGP ILPPESFVVLHRPTQHQILTNLSRKCPSKPV >XP_004045959.1 procollagen C-endopeptidase enhancer 1 [Gorilla gorilla gorilla] MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPPNKECIWIITVP EGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGR GFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPD TYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKE GQGPSPKPGTEPKVKLPPKSQPPEKTEETPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREP GEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQCPPMKKGVSYLLMGQVEENRGPVLPPESFVVL HRPNQDQILTNLSKRKCPSQPVRAAASQD >XP_017895868.1 PREDICTED: procollagen C-endopeptidase enhancer 1 [Capra hircus] MLPAATASLLGPLLTAWALLLPFTHGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITV PKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGG RGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEP DSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSASYRTQPRGATE EGPGEVGPGPKPGAGPKVKPEVPPEEKPKAAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVT GMIKSMVRGPGEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQCPPMKKGISYLLMGQMDKNRGP ILPPESFVVLHRPTQHQILTNLSRKCPSKPV >XP_019333518.1 PREDICTED: procollagen C-endopeptidase enhancer 1 isoform X1 [Alligator mississippiensis] MSPGPGCLLPLLWLCALSRPGLSQGPTAPNASRPVFLCGGEHSGDAGYVASEGFPNFYPPNSDCTWTITV PEGQVVMLTFRVLDLEPDSSCRHDFLEVLSGAQRLARVCGTLRPGTILTPGRRVQLRMVSDEATSGRGFL LWFSGALPHVNGPRRRRPGSKVRAPRVLGESWDYWSDQQFCGGRLEKPQGTIKTPNWPESDYPAGISCSW HIIAPPGKVIELTWGKFDVEADTYCRYDYVSVFQGGQSDDARRVGRFCGDTSPVPIISEGRELLVQFVSD LSVTADGFAATYAARDPEELAERGPSPVAPPPLPPVPEPGTGKGKGGKDPGKAKPPPTAPAPPPLAPEGQ LPSTVPTGPIACPKTCRRTGTLQSNFCASDFVLTGTVKAVTRGPGEGVTATVAVVTVYKAGALALPQPHK GASLRLAVPCRQCPQLKKGASYILMGQLDTGGPWLPPESFVVQFRPPQHQVLTNLSKRSCLPRPQG >XP_020731411.1 procollagen C-endopeptidase enhancer 1 [Odocoileus virginianus texanus] MLPAATASLLGPLLTAWALLLPFTYGQTPNYTRPVFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITV PKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGG RGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEP DSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSATYRTQPRGATE GGPGEVGPGPKPGAGPKVKPEVPPEEKPKAAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVT GMIKSMVRGPGEGLTATVNITGVYKTGGLDLPSPPTDTLLKFYVPCKQCPPMKKGISYLLMGQVDKNRGP ILPPESFVVLHRPTQHQILINLGRKCPSKPV >XP_040202913.1 procollagen C-endopeptidase enhancer 1 [Rana temporaria] MLLSLLLALSLCLGVSWGQQPSPPTPSITRPVFLCGGELTGDSGYVASEGFPSHYPHNKKCTWKITVPDG NIVILSFRLLDMEADPSCRYDYLNIYNGHSESSQRLARVCGTFRPGTIMSTGPQMMLEMGSDEETGGRGF IAWYSAGAPALNENLFCGGKMEKPQGSITSPNWPKSNYPSGITCSWHIVAPKDQVIELVFGKFDVEEDSY CRYDYLAVFNGGQMDNNHQIGKYCGDTPPKTVYSEGNEMLVQFISDLSVTAGGFDVTYRMKDASEIPKVD PESKTKATSVGTASRPDGIKPPAKPKATPKATLKPTPRPTVPKPSSKPATAKPTPKPTTPKPTQKPRPTK ADKLATTAKPKRNNLPAPAGSPAKCPEKCRKTGTLGAHYCANQFVLTGTVKTLTKGEVAGTLLASINIIQ TYKTEGLTIQEAEKTTSVQIVNECPRCPILKKGASYLFMGLVDGEGRGRIVGDSFVIAYRAPQHQILTNV AKKPCS >XP_039272807.1 bone morphogenetic protein 1-like [Styela clava] MADFCRAKFRTEKAFFCADIDPSVCCKRGYFRSVKMASGGCMERQRTNMKFLKTKESLSNVLLHKEIPLMDEQRTLCSGC LNMRSTKTYRRRLTLFAAMAIYILPLLLLQPTGVQGLAPGVTWSVVAGISVINFQIESVNSQEQTTIWVDQPEESEDKIL KDPCKAPLFLGDIALDEVDVEDIFGETVQEFMDHVGNDDSIEARDTTEDDGDDKKSINSQKSKKHSVREASKGLRQNDPS AVDLDEQALRNKTESELSRIPTLREIVRRRKHSKKTEGVKLDSGKRRKNGRRGRKRRGRYRSRIQRTEAVHKRMRRAATA RPERIWPAGVIPYVISANFTGSQRAMFKQAMRHWEAQTCITFIERTDEEAFIKFTYRPCGCCSYVGRRGGGPQAISIGKN CDKFGIVVHELGHVIGFWHEHTRPDRDRHIEIIYKNIQPGQEYNFEKMDSSEINSLGETYDYYSIMHYARNTFSKGMFLD TIKPRVDANGARPTIGQRTRLSDGDVAQAKKLYQCNTCGYTLQDTSGNITSPNYPQYYPAESHCIWRISVTPGEKIVLDI TSLDIYESEGCYYDFLEIRDGHWYRSPKIGQYCGRSLPATITSTDSRLWLQFRTSTYYQGRGFTLKYEAVCGGTIRKESG QIQSPNYPDDYRPSKECIWKVVVDEGFRVGLSFQAFEVERHDTCSYDYLEVRDGPTADSDLIGRFCGYDKPEDVKSTSNT LWIKFVSDGSVNKAGFAASFFKEIDECEDKRKSGCQQGCVNTLGSYKCVCDPGYELAADGRTCEAACGGSVTNLDGYITS PNWPNEYPTNKKCVWQIVAPPQHKISIQFEKFELEGNEVCKYDYVEIRSGLSDDAKFHGRFCGLELPPVIRSTINEMSLA FKSDDTVSKRGFKIKFFSDKDECAISNGGCEHECVNTIGSYSCTCRNGYVLHTNKRGCKEAGCKHDIKTAVGEITSPNWP NKYPSRKECTWLIRTTPGHRVKVVFHEFELETQPECAYDHLELYDGSDSDQTVLGRYCGSKKPGTIVATTSIMFIKFFSD ASVQKRGFSATHQTVCGGNLNASTRSKDLFSHPQYGDNNYISGQECDWIITADTGLVVRLTFTAFEVEEETDCSYDFVEV YDGEDDSATRFGRYCGSKALSTIMSTSGSLLLRFHSDDTINKKGFHARYSSSSYEDISESSSTGRRI >XP_038060665.1 bone morphogenetic protein 1 homolog isoform X2 [Patiria miniata] MGPVTLNHHLHRTFVLSLCLLPCLLLTVHVQSSCAHDLKDGMKLSRHHNKMQDEGDPHVYWRSTVTEEFADPCKADGFLG DIALTEEQYQQEIGRYKQKLQEYKQSKGIRKKTNKQHEEKQLAKEEKRLAKERRKLQRKEKKAIKEEKREERRQSRRPHL ETIQIVQEEETERGTDEVTTETHHRVARAVTSRPERKWPYGVIPYVIDGNFTGSQRAMFKQAMRHWENYTCITFVERSPT QHRNYIVFTYRSCGCCSFVGMRAEGAQAISIGKNCDKFGVVVHELGHVVGFWHEHTRPDRDDHVTIVKENILPGQEYNFN KLLPEEVDSLGQPYDFASIMHYARNTFSRGIWLDTVIPQRDPDAVPRAEIEIGQRKQLSEGDITQANLLYKCPACGRTLQ ETTGNFSSPGWPEQFNSRESCVWRISVTPGETIVLTFEDFELVGSDDCWYHHVEVRDGHWRFSNVLGRFCGSNIPPVIVS TDSRLWIELKSSPTGNAVSRGFAAHYEAVCGGNISKESGMLQSPNYPDDYRPDKSCVWYLTMPEGFQVGLNFQSFEVERH DNCIYDYVEVRDGHEDDSPLIGKYCGYLMPEDIKSSSNKLRVKFVSDGTVNKGGFSADFFKEDDECSKNNGGCEQICVNT IGSYRCECEPGFELKADGESCEVACGGFLTSLQGNITSPSYPDLYPRDKNCVWHLVAPSLYRISLQFLSFELEGNDVCKY DYVEVRSGLTEVGDLHGKFCGDDIPDTITSRYNNMRIEFKSDSTVSRPGFFAMFFADIDECEKNNGDCQHVCVNTLGSYT CSCRNGFTLHENGHDCKESGCRHDIRSSHGEITSPNYPDNYPKRKECTWHIVATPGHKVELVFNDFDLEHHLECAYDHVV IYDGDSSEGHLLGRFCGTRIPDPVLANTNQMYITFFSDASVSRRGFFATHSTICGGVLQADYVSQKLYSHADYGDNNYGS QEDCEWTILAPQGYSVRLMFRSFDIEHETECDYDSLEVLDGDSYDSERIGRFCGHKIPDDIISQGENLRLIFRSDDTISK KGFYAEYQIS >XP_030834881.1 bone morphogenetic protein 1 homolog isoform X1 [Strongylocentrotus purpuratus] MDLLYYMTVSLLGFILSLTTFIGETTRALSDDVSSPCKASGFLGDIALTEDDYEREMIRARHNREQYRRRILQERHTRTT GARHHIKKRTIEEAKVRHVRAVTARPERRWTDAVIPYEIDGNFTGSQRAMFKQAMRHWENYTCITFVERNPANSEHDNHI VFTYQACGCCSFVGRKGDGAQAVSVGKNCDKFGVVVHELGHVVGFWHEHTRPDRNEFVGIVHQNIVPGQEYNFRVLDAAE VDSLGETYDFASIMHYARNTFSRGIWLDTILPRKDPESGIRPEIGQRKHLSEGDIIQANLLYKCPSCGRTLLESTGNFSS PEWPGQYDGDQTCVWRISVTPGETISLQFTGFELVGSDGCWYNYLEVRDGHWRHSPLLGRFCGASLPDPILSSDSRLWIE LKSSAHRYSRGFAANYEAICGGHIERESGTLQSPNYPDDYHPSKECVWLITMPANYTVGLSFQSFEIERHETCIYDYVEV RDGHEDTSPLIGRYCGYFIPDDIKSTGNKMMVTFVSDGSVNKGGFSADFFKEKDECAQPDQGGCMDVCVNTIGSYRCDCR PGYELSSDGRRCEVACGGLFTGLRGNISSPSYPEPYPRDKNCVWQIVAPSNYRISLQFITFDLEGNEVCKYDYVDVRSGL NEEGTLHGKFCGNEIPETITSRFNNLRIDFRSDNTVAKEGFFANFFADVDECEEGNGGCQHICTNTLGSYTCSCRNGFTV HENLHGCKESGCRREIQSTTGIITSPNYPDNYPKRKECTWHISANPGHKIVLSFDDFDLEQHQECTYDRVQVFDGDSDEG QVLGRYCGATIPDAVVSSSNHMFIRFYSDASVSRSGFSATHSTQCGGRLEAELSAQRLYSHADYGDQNYENQESCEWTIV SPDDHFIHLWFRSFDIEHETECNYDQVMILDGDNHAAESFGKFCGHRAPDDIVSSGDSLMITFSSDDTINKKGFLAIFKL TDGELLEGAGEEEEEIYYN >XP_031568191.1 prostasin-like [Actinia tenebrosa] MAVVRLLVAVTIVGLVQSIPLESFFKEDDDSLLVRNIRAPKRLKSNCGSNLQGKTGEVTSPGFPSPYPTGSTCVWTIRVD SKSAIXLNIKEMDIERSKKCRYDSLTMYDGANSKGPELVHLCGSKKPKTSIRSSGNSLYIVFTSDDADTGKGFRATWKAV SRNIKCGGKFTNLTGDISSPHFPNNYPANVDCEWIITVPITHSLTLSFEIFNVEQSAKCSYDNVEIWEGTKKNSPSLGRF CGTNSPGVINAQGTTLRIKLHSDESDTAQGFRAVWTSRSLSGKQTGGRLCGTSAVGTRIVGGVVAKAGAWPWQVAFLWNK GYDKNVQFCGGSLIDPEWVLTAAHCFEITKDKTMYKLRLGEHLLNETEGTEQDFLIDKYYIHPKYNEHTTDNDLALIKLD KPATLNKRVNTICLPEADDEFDTGTLCTISGWGALQEGGITSKVLMQAKVPIVSRDICKHEQSYGEKITPNMLCGGLRQG GVDSCQGDSGGPFVCRNPENPKQWSLVGVTSWGKGCARALKYGVYANVRKXLPWINLLTGNMPTSSPGSTVNTSDSVLTL PPLPGGGGDTIPTLPPLPGLP >NP_001287510.1 tolkin, isoform C [Drosophila melanogaster] MRRRRGTPLGVSWTNCVLLLATGLLVVLISVHAKNPRPHRGLPAPAPAPVPASVDQVATENAHRREPTVDGSVLQRLSGS DRAVDEDEDVDEDEDEGLKHQHLEHRQQFDAYLGTIRRLRRPYRSKYTIEQLMRLHVTPKVSGDIDMDPCKAGGFMGDIA LPEGDSGPVVAHTPIDDEEQERQEVEQLLADSPSPVHDPPSVSGAANSGPTKFNATFQLDLEKLKQEVYHEGLQVEEEGL TDIIRKKTKLPSSGPVNLKAGQSQSQSQSANEPVKPGSESPSDYAQASSYKNEVLPPSEQRIHTDKPARLTLAEIGPKFS NKTQSLHRNVDTRKIQSDNKDIEDDSGNNFVAERRPSQIVPTSLPEQRSTPAHVYSNAGGNGMQLDDEVDFLHSRGVVRR RHRRGPKQRRSNQHLEHEVKLQRLREELSRPVIEAHHHQSHHQKQAQHRQHHQSHHRKKHRRQQQHHRRRGQSTTQYVNH SPPGFNQSQQAQQQSVPEMDLLKAETSKDEEPLRHRVARAVTAKKERIWDYGVIPYEIDGNFSGIHKALFKLAMRHWENS TCIKFVERDPEIHPNYIVFTVRSCGCCSFVGKRGNGPQAISIGRNCDKFGIVVHELGHVVGFWHEHTRPDREKHVVIEHN NIMKGQDYNFNMLSPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRKRPEIGQRLRLSQGDIAQANLLYKC PKCGRTFQESSGIFASPSHYTAGALSNETEHCEWRITATYGERVELKLENMNIFKSNNCETDYLEIRDGYFEKSPLIGRF CGKVDKEVIRTESSRMLLTYVNTHRIEGFRGFKAEFDVVCGGELSVDDAVGRLESPNYPLDYLPNKECVWKITVPESYQV ALKFQSFEVENHDSCVYDYVEVRDGPGQDAPLIGVFCGYKPPPNMKSSGNSMYVKFVSDTSVQKAGFSAVFMKEVDECET QNHGCEHECINTLGGYECSCRIGFELHSDKKHCEDACGGVIEYPNGTITSPSFPEMYPLLKECIWEIVAPPKHRISLNFT HFDLEGTAHQQSDCGYDSVTVYSKLGENRLKRIGTFCGSSIPPTATSESNALRLEFHSDKSIQRSGFAAVFFTDIDECAV NNGGCQHECRNTIGSYICMCHNGYSMHENGHDCKEGECKYEISAPFGTIFSPNYPDSYPPNADCVWHFITTPGHRIKLIF NEFDVESHQECTYDNVAVYDGESESSSVLGRFCGDKIPFPISSTSNQMYMVLKTDKNKQKNGFTASHSTACGGYLRATSQ VQQFYSHARFGNQDYDDGMDCEWTIAAPDNSYVQLIFLTFDIESSENCTFDYVQVFSDIDDVYGQYGPMYGQYCGNVLPQ DINSMTHSLLVRFKTDGSVPMKGFSASYVAVPNSGEYDHSDEDVENSYSSEMVTPFPGSLKSIYIEDTQEETDEYSDFSG NQLVFNGQYRGRYSLPKRYYSGKA >CAE1240683.1 tok [Sepia pharaonis] MLSSGSYLLLFVFLMLCMQFHCQGTVQGLSLPEPKSLPMHRISSKDPVSLYTEQDSTNISYKQPTRKTSNDLYMDPCKAA GFINDIALTDDDVHDLMKMWHNNIEVQVDDPNVRHPRKISEPVSKRRPRKKNKGSHRKRKRCRKKDPKCNKRKSKDTTKK NSPKQKPVSEASRSWRTRRAATARQDRLWEYGVIPYQIEANFSGPHKALFRLAMRHWENHTCITFVERTPEHEDYIVFTE RPCGCCSYVGKRGNGAQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVQIIYKNIMPGQEYNFNKLTPADVNSL GEEYDYGSIMHYARNTFARATFVDTILPKRKYGTRDIGQRIKLSPGDIRQANRLYRCASCGRTLQAATGEFSHKPNQQRT EEREVCEWRISATHGEKIVLNITSLDVPESRNCVTDYLEVRDGYYERSTKLGKFCGKTVPGVLQSTDSRMWLRFVSTQKK GEGFVAKYEAICGGVINKSRGTLTSPNSPDDYRANQECVWRITVPKAYLVGLMFQSFEIENHDNCVYDYLEIRDGPDETS PSLGKFCGYKVPEDIKSSGNQLYVKFVSDGSVQKAGFSATFTEEYNECLTDYHGCDHICVNTLGSYKCMCEIGYELHSDG RKCEDACGGYISIENGTFQSPSFPDLYPTNKYCVWQIVAPKQHRITLNFSYFDLEGNNQDCEYDSVRVSNGLNSDTKAIG IFCGSTLPDSITSSENSLRIEFSSDNSVQKTGFNATFFTDKDECALKNGGCQQICRNTIGSYQCACQNGFTLHENKHDCK EGGCKHQIKTPSGNINSPKWPDFYPSRKDCVWTFTVTDGHRVKLEFEEFELEPHQECTYDHIEIFDGTSTNSRSLGRFCG NKIPPPTYSSGNTMFMIFYSDASVQRKGFSAMHSTVCGGHLLAKTEPKFIYSHAKYGDQNYDNAADCDWIIEAEDDQRIY VEFKAFEIEDESECMYDYVKLYDGKSDTGSAIGKYCGSNKPPPVTSSGRILTIRFVTDDTVNWKGFSLTYRLAEDQSTGG GETQELPEVQG >KAG9429998.1 tolloid-like protein 1 isoform X1 [Apis mellifera carnica] MLRQRLSLRVERVNNFNFSPRCGFLGDIALPNIKYETEWRQQKLNKSFLEELEKYRDEVLKEGLQVEEEGLTEILQFKNG HEANEPHQENEEMVASQEKSEPIMVDRNQYSMDGELEGGFSFNARNEDARPGVRDEGVEFRLESTTPPTKKRHSARKQGR EASQTASNATKSMQAFLRTSEELNVAFPTSTEGTNQMGNLNAENIEQVFTIQPESSTSKQRHRRHHRRRTPKRRHRRRKI PLIRRDLDDSSDEVVSFHDRQLRSIQFYDMEHKWKHGGARKRERFSGRARRAATARKERVWDHGVIPYEIDGNFSGAHKA LFKQAMRHWENFTCVKFVERVPQEHPNYILFTERPCGCCSFVGKRGNGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTR PDRDRHVQIIRDNIMSGQEYNFNKLTEDEVNSLGLPYDYDSIMHYAKNTFSRGTYLDTILPMEVHGKKRPEIGQRLRLSE GDIAQTNLLYKCYKCGRTFQENSGSFGSPTHPNSSPPSEGERCEWRITATHGERIVLNITSLDIFKSNFCRSDYLEIRDG YWYKSNVLGRYCGSGKIHEPVVSTGSRMLVTYVTSNYQSGHRGFTASYEAVCGGEIELEDTGHLESPNYPDGYQSSKECV WKLSVPQNFQVALKFQSFEIENHDNCVYDYVEVRDGHNADSPLIGVYCGYKIPPDIKSTGNKLLVKFVSDGSVQKAGFSA TFMKEFDECVLIDHGCEHNCINTLGGFECSCKPGYELHSDGKHCEDACGGVFEDSNGTITSPSFPVTYPGNKDCVWEIIA PPQYRITLNFTHFDLEGTNARQQECEYDSVEVSSKLGDDILRKHGVFCGSRLPSLITSEGNSMRVTFTSDNSIQKTGFAA VFFTDMDECATNNGGCQHECRNTIGSYQCSCHNGFTLHENGHDCKEGGCKYEIAAPMGTITSPNYPDYYPGLKDCVWHFV TKPGHRIKLVFKVFEMESHQECNYDHIAIYDGDSPDSHVLGKFCGTKEPHPILATGNQMYMVFKSDASVQRKGFFATHST ACGGHLVATNEIRHLYSHARYGVHNYDHRTDCDWAIEAPPGKNVHLTFVTFQLESESDCNYDFVEVYSGLDTSGLLYGRF CGNSNTTDFISINEALLVRFRTDDTISNKGFMALFVAVDRQDSGENYGGSEDEDADEENL >NP_001360030.1 Zinc metalloproteinase nas-39 [Caenorhabditis elegans] MRFSANIAIIVNIIFLFIVVEFVLPTFIRSGDVRFRRYYRNNGRVSRAATAKKERIWPEGIIPFVIASNFSGEHQHLFLR AMRHWENFTCVSFVPRQPHHKHYITFTVDKCGCCSYVGRRGEGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDM YVDIFYKSIQTGQDYNFEKSKPEEVDSLGEPYDFSSIMHYARDTFSRGAFYDTILPKPNSGFRLEIGQRVQLSEGDIRQT KKLYKCAECGGTLMQESGNLAIQHAGVCTWHIISPQGHTIFLNITGSTLSPPSSLCGKEEDNVITVRDGVSISSPVLDRI CGGDSLFRTIASSGNRMLIQVRSSTPAASLPFATYYAICGGPIYANEGVIHSPKYPESYPPNSDCQWTIHVDENSQVAIE FVYFHLEQHKECIYDRLILTEGISKNSKKDGKEMSETFCGLIEKKTIVSKTNQISLRFFSDNSVQKTGFELRFTKELNEC ATDKNICHHYCVNTVGGFKCACRVGYSLSSNGFSCDSTCGGYLKASNGSISSPNFPEMYPNSKTCIWEIEAPDGYHIFLN FTKFNVEGMKTECAYDYVKIGDSEKLCGEYHEALLFTTPRNRVRIEFSSDSSVERDGFFANFIADFDECQNDNAGCEHTC QNRLGSYVCTCNPGYILAEDKHNCKEGSCFFEVNAPAGDINSPNYPNDYPKGQNCSWHFVTTPGHRLMLTFSSFQVEEHA QCKYDAVSVYDGGDGSAQLAGVFCGLAPPPLLLSSSNELYLTFSSDASVSRRGFQAHYTSLCGGRLTAESTPGHIYSHAT FSDSKYGKNQDCSWIVRAKSPGRGVRIQFSTFNIESEEGCQYDYIEIYDGPEATLERLVGRFCGDTSPEVITSTGPELLL IMHTDNAEEEKGFVAEYREAPRSSSTKRTFVSKTRHSPLEEPIHDRNE
Mafft alignment of selected proteins >sp|Q15113|PCOC1_HUMAN Procollagen C-endopeptidase enhancer 1 OS=Homo sapiens OX=9606 GN=PCOLCE PE=1 SV=2 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTACA-LLP------------------------- --------FAQGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVKGE--SGYVASEGFPNLYPPNKECIWTITVPEGQTVSL SFRVFDLELHPACRYDALEVFAGSGTSGQRLGR-----FCGTFRPAP-LVAPGNQVTLRM TTDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPD---- TYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSI-SSEGNELLVQFVSDLSVTADGFSAS YKTL-----PRGTAKEGQG-------------------------PGP----KRGTEPKV- ---------------------KLPPKSQ----------------------------PPE- -KTEE---SPSAP---------------------------------DAP--TCPKQCRRT GTL-----------------QSNFCASS------------LVVTATVKSMVREP------ ------------GEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQ---------- -----------------------------------C------PPMKKGVSYLLMGQVEEN RGPVLPPESFVVLHRPNQDQILTNLSKRKCPSQ--------------------------- ----------------------------------------------PVRAA--------- ----------------------------------------ASQD---------------- ---------------------------------------------------- >tr|B3DJG2|B3DJG2_DANRE Procollagen C-endopeptidase enhancer b OS=Danio rerio OX=7955 GN=pcolceb PE=2 SV=1 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MWAAVRVCH-------------- --------------------------LGLLFLGLG------------------------- --------WVHGQ----------------------SQTN--------------------- ---------------------FTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGHLVTD--SGFVASEGFPSHYKANSKCTWYITVPEGHVVML QFRIFDLEADPTCRYDYVDVYNGHSYTVQKLGR-----FCGTFRPGA-LISTSNTMMLEM ASDSSTGGRGFLAYFSGGKPHVD------------------------------------- EHQFCGGRLTKPQGSVKTPNWPESDYPAGISCSWHISVESNMVIEVKFEKLDLELD---- TYCRYDYVALFNGGETDDSRRIGKFCGDTVPDAV-VTNGNELLVHFVSDLSVTAAGFMAH YRSV-----PRGSRTPTADL---DTVHGPRVNTSPTKPTVPPQRVKPKPTPKPPSRPFKP ------------VPPRPTPKTRSNPAAKPKPVRPTPPTRRSGSKITPKPAVKVTAKPATK PTPKPAI-RPQPKPTSTTAKQEVKPGVKPTAKTISKPGNRTTSRTASAGNPLCSLPCKRI GTM-----------------VTRFCPSH------------FVLTGKVTSLSPGS------ ------------QGSAEVEVSVIKVYKAGRLQLRKRGPSTSATLTATCSK---------- -----------------------------------C------PALRKGVNYVLMGHVNDD GLGILNPSSFALQHKAVHDRALANLAKKAC------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >tr|F1QUX0|F1QUX0_DANRE Procollagen C-endopeptidase enhancer a OS=Danio rerio OX=7955 GN=pcolcea PE=4 SV=1 MRSSV------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------LLDMEHLT--------------- ---------VVW-SL-----------WLLLSLSFG------------------------- --------GVLCQ----------------------T-TN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FNCGGDLVGD--SGFVGSEGFPSFYKPNSKCTWYITVPEGNVVML SFRIFDLEADPLCRYDYVDVYNGHSNMVQKLGR-----FCGTFRPGA-LISTSNTMMVEM VSDSGTGGRGFVAYFNGGKPHVD------------------------------------- EHQFCGGKLTKSQGTIKTPNWPEKNYPPGISCSWLITVEPEMVIEVKFDKFDLESD---- TYCRFDYVAFFNGGEKDDSRRIGKYCGYTAPQNI-VTNSNVLLVQFVSDLSVTSDGFMAS YTSI-----PRGLHSPSAGG---DVVSGPRVSSTPTKPKIIP--AKP-----VVTTEAIT ------------TTTTTTTEAPEQPKPRPKPVRPIKPVKP----------------PVRK PEPE----RPRPA---------------------------------TETNPLCAKACKRD GTI-----------------KTSFCASE------------FVITGTLTALTAGP------ ------------RGSMQGTVSLIKAYKTGRLTITQAGETMSVKLMMPCKK---------- -----------------------------------C------PLLRRGQNYILMGEVDDE GRGVLNPGTFTALYKAPHHKMLTNINNQPC------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >NP_032814.2 procollagen C-endopeptidase enhancer 1 precursor [Mus musculus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAALTS--------------- ---------FLG-PF-----------LLAW--VLP------------------------- --------LARGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKKCIWTITVPEGQTVSL SFRVFDMELHPSCRYDALEVFAGSGTSGQRLGR-----FCGTFRPAP-VVAPGNQVTLRM TTDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRMEKAQGTLTTPNWPESDYPPGISCSWHIIAPSNQVIMLTFGKFDVEPD---- TYCRYDSVSVFNGAVSDDSKRLGKFCGDKAPSPI-SSEGNELLVQFVSDLSVTADGFSAS YRTL-----PRDAVEKESAL--------SPGEDVQRGPQSR---SDP----KTGTGPKV- -------------KPP--TKPKSQPAET----------------------------PEAS PATQA---TPVAP---------------------------------AAPSITCPKQYKRS GTL-----------------QSNFCSSS------------LVVTGTVKTMVRGP------ ------------GEGLTVTVSLLGVYKTGGLDLPSPPSGTSLKLYVPCRQ---------- -----------------------------------M------PPMKKGASYLLMGQVEEN RGPILPPESFVVLYRSNQDQILNNLSKRKCPSQ--------------------------- ----------------------------------------------PRTAA--------- ------------------------------------------------------------ ---------------------------------------------------- >KAB0349382.1 hypothetical protein FD754_014239 [Muntiacus muntjak] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTAWALLLP------------------------- --------FTHGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKECIWTITVPKSQTVSL SFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGR-----FCGTFRPAP-LVASGNQVTLRM RSDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD---- SYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSI-TSEGNELLVQFVSDLSVTADGFSAT YRTQ-----PRGATEGGPGE--------------------VG--PGP----KPGAGPKV- -------------------KPEVPPEEK----------------------------PKAE PKAEA---TPVGP---------------------------------DAPSVTCPKQCRRT GTL-----------------QSHFCNSD------------LVVTGMIKSMVRGP------ ------------GEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQ---------- -----------------------------------C------PPMKKGISYLLMGQVDKN RGPILPPESFVVLHRPTQHQILTNLG-RKCPSK--------------------------- ----------------------------------------------PV------------ ------------------------------------------------------------ ---------------------------------------------------- >KAB0384410.1 hypothetical protein FD755_006327 [Muntiacus reevesi] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTAWALLLP------------------------- --------FTHGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKECIWTITVPKSQTVSL SFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGR-----FCGTFRPAP-LVASGNQVTLRM RSDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD---- SYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSI-TSEGNELLVQFVSDLSVTADGFSAT YRTQ-----PRGATEGGPGE--------------------IG--PGP----KPGAGPKV- -------------------KPEVPPEEK----------------------------PKAE PKAEA---TPVGP---------------------------------DAPSVTCPKQCRRT GTL-----------------QSHFCNSD------------LVVTGMIKSMVRGP------ ------------GEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQ---------- -----------------------------------C------PPMKKGISYLLMGQVDKN RGPILPPESFVVLHRPTQHQILTNLG-RKCPSK--------------------------- ----------------------------------------------PV------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_043310674.1 procollagen C-endopeptidase enhancer 1 isoform X2 [Cervus canadensis] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTAWALLLP------------------------- --------FTHGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKECIWTITVPKSQTVSL SFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGR-----FCGTFRPAP-LVASGNQVTLRM RSDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD---- SYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSI-TSEGNELLVQFVSDLSVTADGFSAT YRTQ-----PRGATEGGPGE--------------------VG--PGP----KPGAGPKV- -------------------KPEVPPEEK----------------------------PKAA PKAEA---TPVGP---------------------------------DAPSVTCPKQCRRT GTL-----------------QSHFCNSD------------LVVTGMIKSMVRGP------ ------------GEGLTATVNVTGVYKAGGLDLPAPPTDTLLKFYVPCKQ---------- -----------------------------------C------PPMKKGISYLLMGQVDKN RGPILPPESFVVLHRPTQHQILTNLG-RKCPSK--------------------------- ----------------------------------------------PV------------ ------------------------------------------------------------ ---------------------------------------------------- >OWK11217.1 PCOLCE [Cervus elaphus hippelaphus] MPGWAGN----------------------------------------------------- -----------------------------------------------------GFVISLT -----------FGKFDLEPDS-------YCR----YDSVSVFNG---------------- --------------PVSDDAKRLG--------------------KFCGDTVPGSITSEGN ELLVQFV--------SDLSVTADGFSATYRTQPR--G---------ATEG------GPGE VGPGPK-----PGAGPKVKPEVPPEEKPKAAPKAEATPVGPDAPSVTCPKQCRRTGTLQS HFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYK-------AGGLDLP-APPT------ --------------DTLLKFYVPCKQCPPMKK----V---------YPTEVLF------- ------------------------------------------------------------ -------------------------------------GLAEATSD--------------- ---------PLGLPPPSPWLPAHPHHLLASP-ALP------------------------- --------HAGLT----------------------S-LL--------------------- ---------------------FPR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKECIWTITVPKSQTVSL SFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGR-----FCGTFRPAP-LVASGNQVTLRM RSDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD---- SYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSI-TSEGNELLVQFVSDLSVTADGFSAT YRTQ-----PRGATEGGPGE--------------------VG--PGP----KPGAGPKV- -------------------KPEVPPEEK----------------------------PKAA PKAEA---TPVGP---------------------------------DAPSVTCPKQCRRT GTL-----------------QSHFCNSD------------LVVTGMIKSMVRGP------ ------------GEGLTATVNVTGVYKAGGLDLPAPPTDTLLKFYVPCKQ---------- -----------------------------------C------PPMKKGISYLLMGQVDKN RGPILPPESFVVLHRPTQHQILTNLG-RKCPSK--------------------------- ----------------------------------------------PV------------ ------------------------------------------------------------ ---------------------------------------------------- >KAF4015881.1 hypothetical protein G4228_007241 [Cervus hanglu yarkandensis] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPASTAS--------------- ---------LLG-PL-----------LTAWALLLP------------------------- --------FTHGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKECIWTITVPKSQTVSL SFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGR-----FCGTFRPAP-LVASGNQVTLRM RSDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD---- SYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSI-TSEGNELLVQFVSDLSVTADGFSAT YRTQ-----PRGATEGGPGE--------------------VG--PGP----KPGAGPKV- -------------------KPEVPPEEK----------------------------PKAA PKAEA---TPVGP---------------------------------DAPSVTCPKQCRRT GTL-----------------QSHFCNSD------------LVVTGMIKSMVRGP------ ------------GEGLTATVNVTGVYKAGGLDLPSPPTDTLLKFYVPCKQ---------- -----------------------------------C------PPMKK------VFRADQR SG----PRQLLTLYNPTGAVLRFRVL-CTAPAKYTVFDAEGYVKPQSCIDIVIRHVAPNP RHYNVQDRFRIELSEEGTEGRVVGRKDITSVLRAPAYPLELQGQSDPTPHAEPHSWTAPS AAQPFPENPHPQLATSSFLLFLLMGTISVAFLLLPLQDELGSQLPQMFHVS--LGQKLV- AAYVLGEPSGSRPSKRRMGAGKRVYRAGRLHTQPCSFFLPSPGLLTMVFLRT >NP_001082711.1 uncharacterized protein LOC398671 precursor [Xenopus laevis] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGR-TL-----------LLCLSLVLG------------------------- --------LSRARNSD-------------------T-NN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDITGD--SGFIGSEGFPNYYPPNKKCVWNITVPDGHVVML TFRLLDMEADPSCRYDYLNIYNGHFETGQRLAR-----VCGTFRPGA-LLSTGPQMMLEM VTDDGTAGRGFLAWYSAGSTQPS------------------------------------- ESQLCGGKLEKPQGSINTPNWPENNYPSGISCSWHIVAPKEKVVELSFGKFDVEGD---- SYCRFDYLAVFNGGETDNTRLIGKFCGDSSPKTI-YSDGNEMLVQFVSDLSVTADGFAVN YRMRDASEVPKTTPTST---------------------------SAP------------- -----------EKKAPLDTKLSNKPSVK-LETIPE---------------------PKTK PTK-----LPKSPDTD------------------------------SSSAVKCPQKCRKT GTL-----------------GSHYCANQ------------FVVTGTVNSLTQGD------ -----------SEKSLLATVTIIKTFKVEGLSIQESGKTMSIKVINECPK---------- -----------------------------------C------PILKKGSSYLFMGEVNAE GQGRIVPESFVIAHKAAQHQILTAISKKPC------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_021147809.1 procollagen C-endopeptidase enhancer 2 [Columba livia] MR---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------CADTPLCPG------------------------- --------GTRGC----------------------S-TA--------------------- --------------PYTIFPIILR-------------PT--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FACGGVVSGE--SGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVL SFRYLDLESDNLCRYDFVDIYNGHA-NGQRIGR-----FCGTVKPGA-LISNSNKMLVQM TSDANTAGSGFIAKFSAAEPHER------------------------------------- GDQYCGGRLEKPSGSFQTPNWPERDYPAGVTCSWHIVAPKNQLIELKFEKFDVERD---- NYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPI-LSERNELLIQFLSDLSLTADGFIGH YKFR-----PKKLPATT------------------------------------------- -------------VPPNTTTLPATSTVK----------------------------P--- ------------------------------------------------TVALCQQKCKRS GTI-----------------ESNYCSSN------------FVITGTVITAVTR------- ------------AGSLHATISIINVYKEGNLAIQQAGKNMSAKIIVVCKQ---------- -----------------------------------C------PLIRRGLNYIIMGQVEED GRGKVFPNSFVMSFKTKNSKILNALKNKTCYN---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_015816628.1 PREDICTED: procollagen C-endopeptidase enhancer 2-like [Nothobranchius furzeri] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------MSPC--------------- ---------CIW-GL-----------LLFLSLTSG------------------------- --------WTKAQ----------------------Q-TN--------------------- ---------------------NTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FYCGGDLVAE--SGFVGSEGFPNFYKPNSKCIWRITVPEGNVVTL SFRIFDLEADSQCRYDYLEVYNGHSNGVQKLGR-----FCGTFRPGA-LISSTNTMMLEM RSDGETQGRGFVAYFSGAKPYVN------------------------------------- DEQFCGGKMTKSQGEIKTPNWPDNKYPPGISCSWIITVEPNQVIQVKFEKFILEAD---- TYCRFDYVLFFNGGERDDSRLIGRYCGDQTPEPI-ITSGNMLLVHFVSDFSVPSDGFFAY YTSI-----PRGSQSATVES-------GARTVSVPSVPVIKP--AEPE---RPVVLRITT ------------TTIPTTSTIPTTTKAR-----------------------------VSR PNGK----RP------------------------------------VLQNPLCAKACKRT GTI-----------------KTAFCSSE------------FVITGKVMSLTPGP------ ------------RGTLHIKVSLIKAYKAGRLTITQVGETMAVKLVSQCKK---------- -----------------------------------C------PLLRRGANHIIMGQVDEE GRGTLAPGAFTAPYKTQQDKLLMNINNQPC------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_040535317.1 procollagen C-endopeptidase enhancer 2 isoform X2 [Gallus gallus] MK---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------SLSE-------------------------- --------VTENC----------------------K-NS--------------------- --------------SF-----VLR-------------PT--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FTCGGVVSGE--SGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVL SFRYLDLESDNLCRYDFVDIYSGHA-NGQRIGR-----FCGTVKPGA-LVSSSNKMLVQM TSDANTAGNGFIAKFSAAEPHER------------------------------------- GDQYCGGRLEKPSGSFQTPNWPERDYPAGVTCSWHIVAPKNQLIELKFEKFDVERD---- NYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPI-VSEKNELFIQFLSDLSLTADGFIGH YKFR-----PKKLPTTT------------------------------------------- -------------VPPTTTTVPATSIPK----------------------------P--- ------------------------------------------------TVALCQQKCKRS GTP-----------------ESNYCSSN------------FVITGTVISTTTR------- ------------AGSLHATISIINVYKEGNLAIQQAGKNMSAKIIVVCKQ---------- -----------------------------------C------PLLRRGLNYIIMGQVEED GRGKIFPNSFVMSFKTKNQKILNSLKNKTCYN---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_031410927.1 procollagen C-endopeptidase enhancer 2 [Meleagris gallopavo] MPG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------ARSPRDTEPLSKNRAQRVTTLGI----------KDNSLLRA----- ------------------------------------------------------------ -------------------------------------LLTAAVRS--------------- ----GEHRVPHHQTLP----PRYSPAAAASSL---------------------------- --------STATC----------------------R-PR--------------------- --------------DE-----AGRAG---GQW-----PT--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FTCGGVVSGE--SGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVL SFRYLDLESDNLCRYDFVDIYSGHT-NGQRIGR-----FCGTVKPGA-LVSSSNKMLVQM TSDANTAGSGFIAKFSAAEPHER------------------------------------- GDQYCGGRLEKPSGSFQTPNWPERDYPAGVTCSWHIVAPKNQLIELKFEKFDVERD---- NYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPI-LSEKNELFIQFLSDLSLTADGFIGH YKFR-----PKKLPTTT------------------------------------------- -------------VPPTTTTIPATSVSK----------------------------P--- ------------------------------------------------TVALCQQKCKRS GTL-----------------ESNYCSSN------------FVITGTVISTTTR------- ------------AGSLHATISIINVYKEGNLAIQQAGKNMSAKIIVICKQ---------- -----------------------------------C------PLIRRGLNYIIMGQVEED GRGKIFPNSFVMSFKTKNQKILNALKNKTCYN---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_030253492.1 procollagen C-endopeptidase enhancer 2 isoform X2 [Sparus aurata] MP---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------FMPRGENRR-----------------------T----- ------------------------------------------------------------ -------------------------------------MWRTC------------------ -------------SV-----------FCAWSLLF-------------------------- --------LAEVC----------------------A-QS--------------------- ---------------------QRR-------------PT--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FTCGGNITGE--SGVIGSQGYPGVYPPNTKCVWRITVPEGKVVVL SFRSIDLESDNLCRYDYVDVYSGHV-SGQRLGR-----FCGTFKPGA-LVSTGNKMLMQM VSDANTAGSGFLAVFSAAHPHER------------------------------------- GDQYCGGRLDRPSGTFKTPNWPEKDYPAGVTCSWHIVAPKNQIIEVKFEKFDVERD---- NYCRYDHVSIFNGAEINDAKRIGKYCGDSPPAPV-FSDGNQLLIQFLSDLSLTADGFIGH YKFR-----PKKFPTTT------------------------------------------- -------------IPPTTTTQPLTTRPI----------------------------PL-- ----------------------------------------------KYSVALCQQKCKRR GTL-----------------ESNYCSSN------------FVITGTVITAVMR------- ------------GGSMFATVSIINVYKEGSLAIQQAGKTMSTKIIILCKK---------- -----------------------------------C------PFIRRGLNYVFMGQVDED GKGKIAPHHFVMAFKTKNQKGLNVLKDKRC------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_004081148.3 procollagen C-endopeptidase enhancer 2 [Oryzias latipes] MP---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------FMSRCERRR-------------------CLLPA----- ------------------------------------------------------------ -------------------------------------MWRAC------------------ -------------CL-----------FCAWSLLL-------------------------- --------LTQVC----------------------A-QS--------------------- ---------------------ERR-------------PI--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FTCGGNITGE--SGVIGSQGYPGVYPPNTKCVWRITVPEGKVVVL SFRTIDLENDNLCRYDYVDVYSGHI-SAQRLGR-----FCGTFKPGS-LVSTGNKMLLQM VSDANTAGSGFLAVFSAAHPHER------------------------------------- GDQYCGGRLVKPNGTFKTPNWPEKDYPAGVTCSWHIVAPKNQIIEVKFEKFDVERD---- NYCRYDHVSIFNGAEINDARRIGKYCGDSPPAPV-FSEGNQVLIQFLSDLSLTADGFIGH YKFR-----PKKFSITT------------------------------------------- -------------APPPTTTHPVTTRPI----------------------------PL-- ----------------------------------------------KYSVALCQQKCKRR GTL-----------------HSNYCSSN------------FVITGTVITAMMK------- ------------GGSMYATVSIINVYKEGNLAIQQAGKTMSTKIIILCKK---------- -----------------------------------C------PFIRRGLNYIFMGQVDEE GRGKIAPQHFVMAFKTKNQKGLNVLKNKQC------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >NP_062110.1 procollagen C-endopeptidase enhancer 1 precursor [Rattus norvegicus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAALTS--------------- ---------LLG-PF-----------LLAW--VLP------------------------- --------LARGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKKCIWTITVPEGQTVSL SFRVFDMELHPSCRYDALEVFAGSGTSGQRLGR-----FCGTFRPAP-VVAPGNQVTLRM TTDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRMEKAQGTLTTPNWPESDYPPGISCSWHIIAPSNQVIMLTFGKFDVEPD---- TYCRYDSVSVFNGAVSDDSKRLGKFCGDKAPSPI-SSEGNELLVQFVSDLSVTADGFSAS YRTL-----PRDAVEKESAP--------SPGEDAQHGPQSR---SDP----KTGTGPKV- -------------KPP--SKPKVQPVEK----------------------------PEGS PATQA---TPVAP---------------------------------DAPSITCPKQYKRS GTL-----------------QSNFCSSS------------LVVTGTVKAMVRGP------ ------------GEGLTVTVSLLGVYKTGDLDLPSPASGTSLKFYVPCKQ---------- -----------------------------------M------PPMKKGASYLLMGQVEEN RGPILPPESFVVLYRPNQDQILSNLSKRKCPSQ--------------------------- ----------------------------------------------PRPDA--------- ------------------------------------------------------------ ---------------------------------------------------- >XP_016801667.1 procollagen C-endopeptidase enhancer 1 [Pan troglodytes] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTACA-LLP------------------------- --------FAQGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVKGE--SGYVASEGFPNLYPPNKECIWTITVPEGQTVSL SFRVFDLELHPACRYDALEVFAGSGTSGQRLGR-----FCGTFRPAP-LVAPGNQVALRM TTDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPD---- TYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSI-SSEGNELLVQFVSDLSVTADGFSAS YKTL-----PRGTAKEGQG-------------------------PGP----KPGTEPKV- ---------------------KLPPKSQ----------------------------PPE- -KTEE---SPSAP---------------------------------DAP--TCPKQCRRT GTL-----------------QSNFCASS------------LVVTATVKSMVREP------ ------------GEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQ---------- -----------------------------------C------PPMKKGVSYLLMGQVEEN RGPVLPPESFVVLHRPNQDQILTNLSKRKCPSQ--------------------------- ----------------------------------------------PVRAA--------- ----------------------------------------ASQD---------------- ---------------------------------------------------- >XP_038394384.1 procollagen C-endopeptidase enhancer 1 isoform X1 [Canis lupus familiaris] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTAWA-LLP------------------------- --------FTQGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKECIWTITVPEGQTVSL SFRVFDLELHPACRYDALEVFAGSGTSGQRLGR-----FCGTFRPAP-LVAPGNQVTLRM TADEGTGGRGFLLWYSGRATSGTGP---PPGARRKWVT---------DPRVEWAAWGYWD EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD---- TYCRYDSVSVFNGAVSDDAKRLGKFCGDTAPGPI-SSEGNELLVQFVSDLSVTADGFSAS YKTL-----PRGAAAEGQAR--------SPGEDARSGASL------P------------- -------------------KPGPPPVEK----------------------------PKAS SEAQA---TPEAP---------------------------------NVPNVSCPKQCRRT GTL-----------------QSNFCSSS------------LVVTATVKSMVRGP------ ------------GEGLTVTVSLIGAYKTGGLDLPSPITDTPLKFYVPCKQ---------- -----------------------------------C------PPMKKGASYLMMGQVEEN RGPILPAESFVVLYRPNQDQILTNLSKRKCPSQ--------------------------- ----------------------------------------------PGRAA--------- ----------------------------------------GSQA---------------- ---------------------------------------------------- >NP_001039353.1 procollagen C-endopeptidase enhancer 1 precursor [Bos taurus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTAWALLLP------------------------- --------FTHGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKECIWTITVPKSQTVSL SFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGR-----FCGTFRPAP-VVASGNQVTLRM RSDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD---- SYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSI-TSEGNELLVQFVSDLSVTADGFSAS YRTQ-----PRGATEGVPGE--------------------VG--LGP----KPGAGPKV- -------------------KPEVPPEEK----------------------------SKAA PKAEA---TPVGP---------------------------------DAPSVTCPKQCRRT GTL-----------------QSHFCNSD------------LVVTGMIKSMVRGP------ ------------GEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQ---------- -----------------------------------C------PPMKKGISYLLMGQVDKN RGPILPPESFVVLHRPTQHQILTNLS-RKCPSK--------------------------- ----------------------------------------------PV------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_017198071.1 PREDICTED: procollagen C-endopeptidase enhancer 1 [Oryctolagus cuniculus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTAWA-LLP------------------------- --------LAQGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGD--SGYVASEGFPNLYPPNKECIWTITVPEGQTVSL SFRVFDLELHPSCRYDALEVFAGSGTSGQRLGR-----FCGTFRPAP-LVAPGNQVTLRM TADEGTGGRGFLLWYSGRATSGTGP---PPGARRKWVT---------DPRVEWAAWGYWD EHQFCGGRMEKEQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFGKFDLEPD---- TYCRYNSVSVFNGAVSDDAKRLGKFCGDTAPGPI-SSEGNELLVQFVSDLSVTADGFSAS YRIL-----PRGTAAQGPAQ--------APGEDARPGPPLVD--SGS----KPGVGPKV- -------------KPP--TKPRVQPAGK----------------------------PEAP PEAKT---PPQDP---------------------------------DVPSIPCPKQCQRT GTM-----------------QSNFCTSN------------LVVTGTVKSIVRGP------ ------------GEGLWVTVSLIGAYKTGGLELPSPPTDASLKFYVPCKH---------- -----------------------------------C------RPLKKGASYLLMGQVKEN GVPVLPPDSFVVLYRPTQHQILTNLSKRKCPSQ--------------------------- ----------------------------------------------PAES---------- ------------------------------------------QV---------------- ---------------------------------------------------- >XP_009240915.1 procollagen C-endopeptidase enhancer 1 isoform X1 [Pongo abelii] M----------------------------------------------------------- ------------------------------------------------------------ -----------------------------C------------------------------ --------------PRPREVPGH-------------------------ATVPPS------ ------------------------------------------------------------ ---------------PLPAPLASPHA---------------------------------- ----------------------------------------------HTPKAAPS------ --------------GADYPAAAATAAAALQNSAAASV---------LRTPAPFPQ----- ------------------------------------------------------------ ------------------------------------AMLPAATAS--------------- ---------LLG-PL-----------LTAWA-LLP------------------------- --------FAQGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVKGE--SGYVASEGFPNLYPPNKECIWTITVPEGQTVSL SFRVFDLELHPACRYDALEVFAGSGTSGQRLGR-----FCGTFRPAP-LVAPGNQVTLRM TADEGTGGRGFLLWYSGRATSGTGP---PPGARRKWVT---------DPRVEWAAWGYWD EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPD---- TYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSI-SSEGNELLVQFVSDLSVTADGFSAS YKTL-----PRGTAK-GQG-------------------------PSP----KPGTEPKV- ---------------------KLPPKSQ----------------------------PPE- -KTEE---TPSAP---------------------------------DAP--TCPKQCRRT GTL-----------------QSNFCASS------------LVVTATVKSMVREP------ ------------GEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQ---------- -----------------------------------C------PPMKKGVSYLLMGQVEEN RGPVLPPESFVVLHRPNQDQILTNLSKRKCPSQ--------------------------- ----------------------------------------------PVRAA--------- ----------------------------------------ASQD---------------- ---------------------------------------------------- >XP_003354522.1 procollagen C-endopeptidase enhancer 1 [Sus scrofa] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTAWA-LLP------------------------- --------FAQGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYLASEGFPNLYPPNKECIWTITVPESQTVSL SFRVFDLELHPSCRYDALEVFAGSGTSGQRLGR-----FCGTFRPAP-LVAPGNQVTLRM TSDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD---- SYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPI-SSEGNELLVQFVSDLSVTADGFSAS YRTL-----PRGATEKAPAQ--------SPGEDARPSPPLLG--PGP----KPGAGPKV- -------------------KPELPPEEK----------------------------PKAA PKAEA---TPAGS---------------------------------DGPSVPCPKQCRRT GTL-----------------QSNFCNSN------------LVVTATVKSMVRGP------ ------------GEGLTVTVSLIGVYKTGGLDLPSPPTDTSLKFYAPCKQ---------- -----------------------------------C------PPMKKGTSYLMMGQVDEN RGPILPPESFVVLYRPNQDQILTNLAKRRCPSQ--------------------------- ----------------------------------------------PVQAA--------- ----------------------------------------ESQA---------------- ---------------------------------------------------- >XP_003812960.2 procollagen C-endopeptidase enhancer 1 [Pan paniscus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTACA-LLP------------------------- --------FAQGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVKGE--SGYVASEGFPNLYPPNKECIWTITVPEGQTVSL SFRVFDLELHPACRYDALEVFAGSGTSGQRLGR-----FCGTFRPAP-LVAPGNQVALRM TTDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPD---- TYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSI-SSEGNELLVQFVSDLSVTADGFSAS YKTL-----PRGTAKEGQG-------------------------PGP----KPGTEPKV- ---------------------KLPPKSQ----------------------------PPE- -KTEE---SPSAP---------------------------------DAP--TCPKQCRRT GTL-----------------QSNFCASS------------LVVTATVKSMVREP------ ------------GEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQ---------- -----------------------------------C------PPMKKGVSYLLMGQVEEN RGPVLPPESFVVLHRPNQDQILTNLSKRKCPSQ--------------------------- ----------------------------------------------PVRAA--------- ----------------------------------------ASQD---------------- ---------------------------------------------------- >XP_006942048.3 procollagen C-endopeptidase enhancer 1 isoform X1 [Felis catus] M----------------------------------------------------------- ------------------------------------------------------------ -----------------------------C------------------------------ --------------PRPREAPGL-------------------------TTVPTALS---- ------------------------------------------------------------ ---------------LSRLPHRPPRW-----------PV--------------------- ----------------------------------------------PTP-THPR------ --------------LPHLALIIPAAAAAAAKLSCCLV---------SRTPAPLPP----- ------------------------------------------------------------ ------------------------------------AMLPAATAS--------------- ---------LLG-PL-----------LTAWA-LLP------------------------- --------FAQGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKECIWTITVPEGQTVSL SFRVFDFELHPACRYDALEVFAGSGTSGQRLGR-----FCGTFRPAP-LVAPGNQVTLRM TADEGTGGRGFLLWYSGRATSGTGP---PPGARRKWVT---------DPRVEWAAWGYWD EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD---- TYCRYDSVSVFNGAASDDAKRLGKFCGDTAPGTI-SSEGNELLVQFVSDLSVTADGFSAS YKTL-----PRGAAKEAQAQ--------SAGEDARSGTPILS--PGP------------- -------------------KPGLPSEEK----------------------------PKAS SEAQA---TPGGP---------------------------------DVPSVPCPKQCRRT GTL-----------------QSNFCTSN------------LVVTATVKSMVRGP------ ------------GEGLTVTVSLIGAYKTGGLDLPSPLTDTPLKFYVPCKQ---------- -----------------------------------C------PPMKKGVSYLMMGQVEEN RGPTLPPESFVVLYRSNQDQILTNLSKRKCPSQ--------------------------- ----------------------------------------------PVRAA--------- ----------------------------------------GSQA---------------- ---------------------------------------------------- >XP_004021061.1 procollagen C-endopeptidase enhancer 1 [Ovis aries] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------FLG-PL-----------LTAWALLLP------------------------- --------FTHGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKECIWTITVPKSQTVSL SFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGR-----FCGTFRPAP-LVASGNQVTLRM RSDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD---- SYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSI-TSEGNELLVQFVSDLSVTADGFSAS YRIQ-----PRGATEEGPGE--------------------VG--PGP----KPGAGPKV- -------------------KPEVPPEEK----------------------------PKAA PKAEA---TPVGP---------------------------------DAPSVTCPKQCRRT GTL-----------------QSHFCNSD------------LVVTGMIKSMVRGP------ ------------GEGLTATVNVTGVYKTGGLDLPSPPTDSLLKFYVPCKQ---------- -----------------------------------C------PPMKKGISYLLMGQMDKN RGPILPPESFVVLHRPTQHQILTNLS-RKCPSK--------------------------- ----------------------------------------------PV------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_004045959.1 procollagen C-endopeptidase enhancer 1 [Gorilla gorilla gorilla] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTACA-LLP------------------------- --------FAQGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVKGE--SGYVASEGFPNLYPPNKECIWIITVPEGQTVSL SFRVFDLELHPACRYDALEVFAGSGTSGQRLGR-----FCGTFRPAP-LVAPGNQVTLRM TTDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPD---- TYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSI-SSEGNELLVQFVSDLSVTADGFSAS YKTL-----PRGTAKEGQG-------------------------PSP----KPGTEPKV- ---------------------KLPPKSQ----------------------------PPE- -KTEE---TPSAP---------------------------------DAP--TCPKQCRRT GTL-----------------QSNFCASS------------LVVTATVKSMVREP------ ------------GEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQ---------- -----------------------------------C------PPMKKGVSYLLMGQVEEN RGPVLPPESFVVLHRPNQDQILTNLSKRKCPSQ--------------------------- ----------------------------------------------PVRAA--------- ----------------------------------------ASQD---------------- ---------------------------------------------------- >XP_017895868.1 PREDICTED: procollagen C-endopeptidase enhancer 1 [Capra hircus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTAWALLLP------------------------- --------FTHGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKECIWTITVPKSQTVSL SFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGR-----FCGTFRPAP-LVASGNQVTLRM RSDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD---- SYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSI-TSEGNELLVQFVSDLSVTADGFSAS YRTQ-----PRGATEEGPGE--------------------VG--PGP----KPGAGPKV- -------------------KPEVPPEEK----------------------------PKAA PKAEA---TPVGP---------------------------------DAPSVTCPKQCRRT GTL-----------------QSHFCNSD------------LVVTGMIKSMVRGP------ ------------GEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQ---------- -----------------------------------C------PPMKKGISYLLMGQMDKN RGPILPPESFVVLHRPTQHQILTNLS-RKCPSK--------------------------- ----------------------------------------------PV------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_019333518.1 PREDICTED: procollagen C-endopeptidase enhancer 1 isoform X1 [Alligator mississippiensis] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MSPGPG----------------- ---------CLL-PL-----------LWLCALSRP------------------------- -------GLSQGP----------------------TAPN--------------------- ---------------------ASR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGEHSGD--AGYVASEGFPNFYPPNSDCTWTITVPEGQVVML TFRVLDLEPDSSCRHDFLEVLSG----AQRLAR-----VCGTLRPGT-ILTPGRRVQLRM VSDEATSGRGFLLWFSGALPHVNGPRRRRPGSK---VR---------APRVLGESWDYWS DQQFCGGRLEKPQGTIKTPNWPESDYPAGISCSWHIIAPPGKVIELTWGKFDVEAD---- TYCRYDYVSVFQGGQSDDARRVGRFCGDTSPVPI-ISEGRELLVQFVSDLSVTADGFAAT YAARD----PEELAERGPSP---------------VAPPPLP--PVP----EPGTGKGKG ------------GKDPGKAKPPPTAPAP----------------------------PPLA PEGQ----LPSTV---------------------------------PTGPIACPKTCRRT GTL-----------------QSNFCASD------------FVLTGTVKAVTRGP------ ------------GEGVTATVAVVTVYKAGALALPQPHKGASLRLAVPCRQ---------- -----------------------------------C------PQLKKGASYILMGQLDTG G-PWLPPESFVVQFRPPQHQVLTNLSKRSCLPR--------------------------- ----------------------------------------------PQ------------ ------------------------------------------------------------ -----G---------------------------------------------- >XP_020731411.1 procollagen C-endopeptidase enhancer 1 [Odocoileus virginianus texanus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------MLPAATAS--------------- ---------LLG-PL-----------LTAWALLLP------------------------- --------FTYGQ----------------------T-PN--------------------- ---------------------YTR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGDVTGE--SGYVASEGFPNLYPPNKECIWTITVPKSQTVSL SFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGR-----FCGTFRPAP-LVASGNQVTLRM RSDEGTGGRGFLLWYSGRATSGT------------------------------------- EHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPD---- SYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSI-TSEGNELLVQFVSDLSVTADGFSAT YRTQ-----PRGATEGGPGE--------------------VG--PGP----KPGAGPKV- -------------------KPEVPPEEK----------------------------PKAA PKAEA---TPVGP---------------------------------DAPSVTCPKQCRRT GTL-----------------QSHFCNSD------------LVVTGMIKSMVRGP------ ------------GEGLTATVNITGVYKTGGLDLPSPPTDTLLKFYVPCKQ---------- -----------------------------------C------PPMKKGISYLLMGQVDKN RGPILPPESFVVLHRPTQHQILINLG-RKCPSK--------------------------- ----------------------------------------------PV------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_040202913.1 procollagen C-endopeptidase enhancer 1 [Rana temporaria] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MLL-SL-----------LLALSLCLG------------------------- --------VSWGQQPSP-----------------PT-PS--------------------- ---------------------ITR-------------PV--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------FLCGGELTGD--SGYVASEGFPSHYPHNKKCTWKITVPDGNIVIL SFRLLDMEADPSCRYDYLNIYNGHSESSQRLAR-----VCGTFRPGT-IMSTGPQMMLEM GSDEETGGRGFIAWYSAGAPALN------------------------------------- ENLFCGGKMEKPQGSITSPNWPKSNYPSGITCSWHIVAPKDQVIELVFGKFDVEED---- SYCRYDYLAVFNGGQMDNNHQIGKYCGDTPPKTV-YSEGNEMLVQFISDLSVTAGGFDVT YRMKDASEIPKVDPESK-------------TKATSVGTASRPDGIKP------------- -----------PAKPKATPKATLKPTPR--PTVPKPSSKPATAK------------PTPK PTTPKPTQKPRPTKADK-------------LATTAKP-KRNNLPAPAGSPAKCPEKCRKT GTL-----------------GAHYCANQ------------FVLTGTVKTLTKGE------ -----------VAGTLLASINIIQTYKTEGLTIQEAEKTTSVQIVNECPR---------- -----------------------------------C------PILKKGASYLFMGLVDGE GRGRIVGDSFVIAYRAPQHQILTNVAKKPC--S--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_039272807.1 bone morphogenetic protein 1-like [Styela clava] MADF-----------C-------------------------------------------- ------------------------------------------------------------ ---RAKFRTEKAFF-------CADIDPSVCCKRGYFRSVKMASG--GCMERQRTNMKFLK TKESLSNVLLHKEIPLMDEQRTLCSG-------CLNMRSTKTYRRRLTLFAAMAIYI--- --LPLLL-----LQPTGVQGLAPGVTWSVVAGISVI---------------------NFQ IESVNS-----QEQTTIWVDQ----------PEESEDKILKDP--------CKAPLFLGD IALDEVDV-----EDIFGETVQEFMDHVGNDDSIE-----------ARDTTE-------- --------DDGD---DKKSINSQKSKKHSVREASKGLRQNDPSAVDLDEQALRNKTESEL SRIPTLREIVRRRKHSKKTEGVKLDSGKRRKNGRRG-------RKRRGRYRS-------- --------------------------RIQRTEAVHKRMRRAATARPERIWPAGVIPYVIS ANFTGSQRAMFKQAM------RHWEAQTCITFIERTD----EEAFIKFTYRPCGCCSYVG RRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHIEIIYKNIQPGQEYNFE KMDSSEINSLGETYDYYSIMHYARNTFSKGMFLDTIKPRVDA-NGARP--TIGQRTRLSD GDVAQAKKLYQCNTCGYTLQDTSGNITSPNYPQY---YPAESHCIWRISVTPGEKIVLDI TSLDIY-ESEGC---YYDFLEIRDGHWYRSPKIGQYCGR-SLPATITSTDSRLWLQFRTS --TYYQGRGFTLKYEAVCGGTIRKE--SGQIQSPNYPDDYRPSKECIWKVVVDEGFRVGL SFQAFEVERHDTCSYDYLEVRDGPTADSDLIGR-----FCGYDKPED-VKSTSNTLWIKF VSDGSVNKAGFAASFFKEIDECEDK--RKSGCQQGCVNTLGSYKCVCDPGYELAA-DGRT CEAACGGSVTNLDGYITSPNWPN-EYPTNKKCVWQIVAPPQHKISIQFEKFELEGN---- EVCKYDYVEIRSGLSDDA-KFHGRFCGLELPPVI-RSTINEMSLAFKSDDTVSKRGFKIK FFSDK----DECAISNGGCEHECVNTIGSYSCTCRNGYVLHTNKRGC----KEAGCKHDI ------------KTAVGEITSPNWPNKY----------------------------PSRK ECTWLIRTTPGHR-----------------VKVVFHEFELETQPECAYDHLELYDGSDSD QTV-----------------LGRYCGSKKPGTIVATTSIMFIKFFSDASVQKRGFSATHQ T---------VCGGNLNASTRSKDLFSHPQYGDNNYISGQECDWIITADT-GLVVRLTFT AFEVEEETDCSYDFVEVYDGED----DSATRFGRYCGSKALSTIMSTSGSLLLRFHSDD- ---TINKKGFHARYSSSSYEDISESSSTGRRI---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_038060665.1 bone morphogenetic protein 1 homolog isoform X2 [Patiria miniata] M----------------------------------------------------------- ------------------------------------------------------------ ----------------------------------------------GPV----------- -----------------------------------------TLNHHLHRTFVLSLCL--- --LPCLLL-TVHVQSSCAHDLKDGMKLS-----------------------------RHH NKMQDE-----GDPHVYW--------------RSTVTEEFADP--------CKADGFLGD IALTEEQY-----QQEIGRYKQKLQEYK-------------------------------- ---------------QSKGIRKKTNKQHEEKQLAK------------EEKRLAKE----- ----------RRKLQRKEKKAIKEEKREERRQSRRPHLETIQIVQEEETERG-------- --------------------------TDEVTTETHHRVARAVTSRPERKWPYGVIPYVID GNFTGSQRAMFKQAM------RHWENYTCITFVERSP--TQHRNYIVFTYRSCGCCSFVG MRAEGAQAISIGKNCDKFGVVVHELGHVVGFWHEHTRPDRDDHVTIVKENILPGQEYNFN KLLPEEVDSLGQPYDFASIMHYARNTFSRGIWLDTVIPQRDPDAVPRAEIEIGQRKQLSE GDITQANLLYKCPACGRTLQETTGNFSSPGWPEQ---FNSRESCVWRISVTPGETIVLTF EDFELV-GSDDC---WYHHVEVRDGHWRFSNVLGRFCGS-NIPPVIVSTDSRLWIELKSS PTGNAVSRGFAAHYEAVCGGNISKE--SGMLQSPNYPDDYRPDKSCVWYLTMPEGFQVGL NFQSFEVERHDNCIYDYVEVRDGHEDDSPLIGK-----YCGYLMPED-IKSSSNKLRVKF VSDGTVNKGGFSADFFKEDDECSK---NNGGCEQICVNTIGSYRCECEPGFELKA-DGES CEVACGGFLTSLQGNITSPSYPD-LYPRDKNCVWHLVAPSLYRISLQFLSFELEGN---- DVCKYDYVEVRSGLTEVG-DLHGKFCGDDIPDTI-TSRYNNMRIEFKSDSTVSRPGFFAM FFADI----DECEKNNGDCQHVCVNTLGSYTCSCRNGFTLHENGHDC----KESGCRHDI ------------RSSHGEITSPNYPDNY----------------------------PKRK ECTWHIVATPGHK-----------------VELVFNDFDLEHHLECAYDHVVIYDGDSSE GHL-----------------LGRFCGTRIPDPVLANTNQMYITFFSDASVSRRGFFATHS T---------ICGGVLQADYVSQKLYSHADYGDNNYGSQEDCEWTILAPQ-GYSVRLMFR SFDIEHETECDYDSLEVLDGDS----YDSERIGRFCGHKIPDDIISQGENLRLIFRSDD- ---TISKKGFYAEYQIS------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_030834881.1 bone morphogenetic protein 1 homolog isoform X1 [Strongylocentrotus purpuratus] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------DLLYYMTVSL--- --LGFIL----------------------------------------------------- ------------SLTTFIGE-----------TTRALSDDVSSP--------CKASGFLGD IALTEDDY-----EREM------------------------------------------- -------------------IRARHNREQYRR-------------------RILQE----- ----------RHTRTTGARHHIKKRTIEEAKV---------------------------- ------------------------------------RHVRAVTARPERRWTDAVIPYEID GNFTGSQRAMFKQAM------RHWENYTCITFVERNPANSEHDNHIVFTYQACGCCSFVG RKGDGAQAVSVGKNCDKFGVVVHELGHVVGFWHEHTRPDRNEFVGIVHQNIVPGQEYNFR VLDAAEVDSLGETYDFASIMHYARNTFSRGIWLDTILPRKDPESGIRP--EIGQRKHLSE GDIIQANLLYKCPSCGRTLLESTGNFSSPEWPGQ---YDGDQTCVWRISVTPGETISLQF TGFELV-GSDGC---WYNYLEVRDGHWRHSPLLGRFCGA-SLPDPILSSDSRLWIELKSS --AHRYSRGFAANYEAICGGHIERE--SGTLQSPNYPDDYHPSKECVWLITMPANYTVGL SFQSFEIERHETCIYDYVEVRDGHEDTSPLIGR-----YCGYFIPDD-IKSTGNKMMVTF VSDGSVNKGGFSADFFKEKDECAQP--DQGGCMDVCVNTIGSYRCDCRPGYELSS-DGRR CEVACGGLFTGLRGNISSPSYPE-PYPRDKNCVWQIVAPSNYRISLQFITFDLEGN---- EVCKYDYVDVRSGLNEEG-TLHGKFCGNEIPETI-TSRFNNLRIDFRSDNTVAKEGFFAN FFADV----DECEEGNGGCQHICTNTLGSYTCSCRNGFTVHENLHGC----KESGCRREI ------------QSTTGIITSPNYPDNY----------------------------PKRK ECTWHISANPGHK-----------------IVLSFDDFDLEQHQECTYDRVQVFDGDSDE GQV-----------------LGRYCGATIPDAVVSSSNHMFIRFYSDASVSRSGFSATHS T---------QCGGRLEAELSAQRLYSHADYGDQNYENQESCEWTIVSPD-DHFIHLWFR SFDIEHETECNYDQVMILDGDN----HAAESFGKFCGHRAPDDIVSSGDSLMITFSSDD- ---TINKKGFLAIFKLTDGELLEGAGEEEEEIYYN------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------- >XP_031568191.1 prostasin-like [Actinia tenebrosa] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------AV-----VRLLVAVTIVGLVQSIP----------------------- ---------------------------LESFFKE---DD--------------------- -------DSL-----------LVRNIRA---------PKRLK------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------SNCGSNLQGK--TGEVTSPGFPSPYPTGSTCVWTIRVDSKSAIXL NIKEMDIERSKKCRYDSLTMYDGANSKGPELVH-----LCGSKKPKTSIRSSGNSLYIVF TSDDADTGKGFRATWKAVS----------------------------------------- RNIKCGGKFTNLTGDISSPHFPN-NYPANVDCEWIITVPITHSLTLSFEIFNVEQS---- AKCSYDNVEIWEGTKKNS-PSLGRFCGTNSPGVI-NAQGTTLRIKLHSDESDTAQGFRAV WTSR-----SLSGKQTGG-----------RLCGTSAVGTRIVGGVVA----KAGAWPWQV AFLWNKGYDKNVQFCGGSLIDPEWVLTA------------------------AHCFEITK DKTMYKLRLGEHLLNETEGTEQ--------DFLIDKYYIHPKYNEHTTDNDLALIKLDKP ATLNKRVNTICLPEADDEFDTGTLCTISGWGALQEGGITSKVLMQAKVPIVSRDICKHEQ SYGEKITPNMLCGGLRQGGVDSCQGDSGGPFVCRNPENPKQWSLVGVTSW---------- --------------------------------GKGC---------ARALKYGVYANVRK- ---XLPWINLLTGNMPTSSPGSTVNTSDSVLTL--------------------------- ---------------------------------------------PPLPGG--------- ---------------------------------------GGDTIPTL------------- -------P-------------------------------PLPGLP------- >NP_001287510.1 tolkin, isoform C [Drosophila melanogaster] MRRRRGTPLGVSWTNCVLLLATGLLVVLISVHAKNPRPHRGLPAPAPAPVPASVDQVATE NAHRREPTVDGSVLQRLSGSDRAVDEDEDVDEDEDEGLKHQHLEHRQQFDAYLGTIRRLR RPYRSKYTIEQLMRLHVTPKVSGDIDMDPCKAGGFMGDIALPEGDSGPVVAHTPIDDEEQ ERQEVEQLLADSPSPVHDPPSV--SGAANSGPTKFNATFQLDLEKLKQEVYHEGLQVE-E EGLTDIIRKKTKLPSSGPVNLKAGQSQSQSQSA------------------------NEP VKPGSESPSDYAQASSYKNEVLPPSEQRIHTDKPARLTLAEIG--------PKFSNKTQS LHRNVDT-------RKIQSDNKDIEDDSGNNFVAERRPSQIVPTSLPEQRSTPAHVYSNA GGNGMQLDDEVDFLHSRGVVRRRHRRGPKQRRSNQHLEH------EVKLQRLREE----L SR-PVIEAHHHQSHHQKQAQHRQHHQSHHRKKHRR--------QQQHHRRRGQSTTQYVN HSPPGFNQSQQAQQQSVPEMDLLKAETSKDEEPLRHRVARAVTAKKERIWDYGVIPYEID GNFSGIHKALFKLAM------RHWENSTCIKFVERDP--EIHPNYIVFTVRSCGCCSFVG KRGNGPQAISIGRNCDKFGIVVHELGHVVGFWHEHTRPDREKHVVIEHNNIMKGQDYNFN MLSPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMK-GRKRP--EIGQRLRLSQ GDIAQANLLYKCPKCGRTFQESSGIFASPSHYTAGALSNETEHCEWRITATYGERVELKL ENMNIF-KSNNC---ETDYLEIRDGYFEKSPLIGRFCGK-VDKEVIRTESSRMLLTYVNT H-RIEGFRGFKAEFDVVCGGELSVDDAVGRLESPNYPLDYLPNKECVWKITVPESYQVAL KFQSFEVENHDSCVYDYVEVRDGPGQDAPLIGV-----FCGYKPPPN-MKSSGNSMYVKF VSDTSVQKAGFSAVFMKEVDECET---QNHGCEHECINTLGGYECSCRIGFELHS-DKKH CEDACGGVIEYPNGTITSPSFPE-MYPLLKECIWEIVAPPKHRISLNFTHFDLEGTAHQQ SDCGYDSVTVYSKLGENRLKRIGTFCGSSIPPTA-TSESNALRLEFHSDKSIQRSGFAAV FFTDI----DECAVNNGGCQHECRNTIGSYICMCHNGYSMHENGHDC----KEGECKYEI ------------SAPFGTIFSPNYPDSY----------------------------PPNA DCVWHFITTPGHR-----------------IKLIFNEFDVESHQECTYDNVAVYDGESES SSV-----------------LGRFCGDKIPFPISSTSNQMYMVLKTDKNKQKNGFTASHS T---------ACGGYLRATSQVQQFYSHARFGNQDYDDGMDCEWTIAAPD-NSYVQLIFL TFDIESSENCTFDYVQVFSDIDDVYGQYGPMYGQYCGNVLPQDINSMTHSLLVRFKTDG- ---SVPMKGFSASYVAVPNSGEYDHSDEDVENSYSS------------------------ -----------EM-------------------------------VTPFPGSLK------- ---------------------------SI---------YIEDTQEETDEYSDFSGNQLVF NGQYRGRY-------------------------------SLPKRYYSG--KA >CAE1240683.1 tok [Sepia pharaonis] M----------------------------------------------------------- ------------------------------------------------------------ ----------------------------------------LSSG---------------- --------------------------------------------SYLLLFVFLMLCMQ-F H----------------CQGTVQGLSLPEPKSL--------------------------P MHRISS-----KDPVSLYTEQDSTNISYKQPTRKTSNDLYMDP--------CKAAGFIND IALTDDDV-----HDLMKMWHNNIEVQVDDPNVRH-----------PRKISEPV------ ---------------SKRRPRKKNKGSHRKRKRCRK-----------KDPKCNK------ ----------RKSKDTTKKNSPKQKPVSEASRS--------------------------- -----------------------------------WRTRRAATARQDRLWEYGVIPYQIE ANFSGPHKALFRLAM------RHWENHTCITFVERTP---EHEDYIVFTERPCGCCSYVG KRGNGAQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVQIIYKNIMPGQEYNFN KLTPADVNSLGEEYDYGSIMHYARNTFARATFVDTILPKRK--YGTR---DIGQRIKLSP GDIRQANRLYRCASCGRTLQAATGEFSHKPNQQR---TEEREVCEWRISATHGEKIVLNI TSLDVP-ESRNC---VTDYLEVRDGYYERSTKLGKFCGK-TVPGVLQSTDSRMWLRFVST ---QKKGEGFVAKYEAICGGVINKS--RGTLTSPNSPDDYRANQECVWRITVPKAYLVGL MFQSFEIENHDNCVYDYLEIRDGPDETSPSLGK-----FCGYKVPED-IKSSGNQLYVKF VSDGSVQKAGFSATFTEEYNECLT---DYHGCDHICVNTLGSYKCMCEIGYELHS-DGRK CEDACGGYISIENGTFQSPSFPD-LYPTNKYCVWQIVAPKQHRITLNFSYFDLEGN---N QDCEYDSVRVSNGLNSDT-KAIGIFCGSTLPDSI-TSSENSLRIEFSSDNSVQKTGFNAT FFTDK----DECALKNGGCQQICRNTIGSYQCACQNGFTLHENKHDC----KEGGCKHQI ------------KTPSGNINSPKWPDFY----------------------------PSRK DCVWTFTVTDGHR-----------------VKLEFEEFELEPHQECTYDHIEIFDGTSTN SRS-----------------LGRFCGNKIPPPTYSSGNTMFMIFYSDASVQRKGFSAMHS T---------VCGGHLLAKTEPKFIYSHAKYGDQNYDNAADCDWIIEAED-DQRIYVEFK AFEIEDESECMYDYVKLYDGKS----DTGSAIGKYCGSNKPPPVTSSGRILTIRFVTDD- ---TVNWKGFSLTYRLAEDQS----TGGGETQE--------------------------- ---------------------------------------------LPEVQG--------- ------------------------------------------------------------ ---------------------------------------------------- >KAG9429998.1 tolloid-like protein 1 isoform X1 [Apis mellifera carnica] MLRQ-------------------------------------------------------- ------------------------------------------------------------ ---RLSLRVERVNNFNFSPR---------C---GFLGDIALPNI-----------KYETE WRQQ-----------------------------KLNKSFLEELEKYRDEVLKEGLQVE-E EGLTEILQFKNGHEANEPHQENEEMVASQEKSEPIMVDRNQYSMDGELEGGFSFNARNED ARPGVR-----DEGVEFRLESTTPPTKKRHSARKQGREASQTA--------SNATKSMQA FLRTSEEL-----NVAFPTSTEG-TNQMGNLNAEN---IEQVFTIQPESST--------- ---------------SKQRHRRHHRRRTPKRRHRRR-----------KIPLIRRD----L DD----SSDEVVSFHDRQLRSIQFYDMEHKWKHGG--------ARKRERFSG-------- ------------------------------------RARRAATARKERVWDHGVIPYEID GNFSGAHKALFKQAM------RHWENFTCVKFVERVP--QEHPNYILFTERPCGCCSFVG KRGNGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVQIIRDNIMSGQEYNFN KLTEDEVNSLGLPYDYDSIMHYAKNTFSRGTYLDTILPMEVH-GKKRP--EIGQRLRLSE GDIAQTNLLYKCYKCGRTFQENSGSFGSPTHPNSSP-PSEGERCEWRITATHGERIVLNI TSLDIF-KSNFC---RSDYLEIRDGYWYKSNVLGRYCGSGKIHEPVVSTGSRMLVTYVTS N-YQSGHRGFTASYEAVCGGEIELED-TGHLESPNYPDGYQSSKECVWKLSVPQNFQVAL KFQSFEIENHDNCVYDYVEVRDGHNADSPLIGV-----YCGYKIPPD-IKSTGNKLLVKF VSDGSVQKAGFSATFMKEFDECVL---IDHGCEHNCINTLGGFECSCKPGYELHS-DGKH CEDACGGVFEDSNGTITSPSFPV-TYPGNKDCVWEIIAPPQYRITLNFTHFDLEGTNARQ QECEYDSVEVSSKLGDDILRKHGVFCGSRLPSLI-TSEGNSMRVTFTSDNSIQKTGFAAV FFTDM----DECATNNGGCQHECRNTIGSYQCSCHNGFTLHENGHDC----KEGGCKYEI ------------AAPMGTITSPNYPDYY----------------------------PGLK DCVWHFVTKPGHR-----------------IKLVFKVFEMESHQECNYDHIAIYDGDSPD SHV-----------------LGKFCGTKEPHPILATGNQMYMVFKSDASVQRKGFFATHS T---------ACGGHLVATNEIRHLYSHARYGVHNYDHRTDCDWAIEAPP-GKNVHLTFV TFQLESESDCNYDFVEVYSGLD----TSGLLYGRFCGNSNTTDFISINEALLVRFRTDD- ---TISNKGFMALFVAVDRQDSGENYGGSEDED--------------------------- ---------------------------------------------ADEENL--------- ------------------------------------------------------------ ---------------------------------------------------- >NP_001360030.1 Zinc metalloproteinase nas-39 [Caenorhabditis elegans] MR---------------------------------------------------------- ------------------------------------------------------------ ----------------------------------FSANIAIIVN---------------- -------------------------------------------------IIFLFIVVE-F V-LPTFI----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------RSGDVR--------------------------------------- -------------------------------------------FRRYYRNNG-------- ------------------------------------RVSRAATAKKERIWPEGIIPFVIA SNFSGEHQHLFLRAM------RHWENFTCVSFVPRQP---HHKHYITFTVDKCGCCSYVG RRGEGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDMYVDIFYKSIQTGQDYNFE KSKPEEVDSLGEPYDFSSIMHYARDTFSRGAFYDTILPKPN--SGFRL--EIGQRVQLSE GDIRQTKKLYKCAECGGTLMQESGNLA----------IQHAGVCTWHIISPQGHTIFLNI TGSTLSPPSSLCGKEEDNVITVRDGVSISSPVLDRICGGDSLFRTIASSGNRMLIQVRSS --TPAASLPF-ATYYAICGGPIYAN--EGVIHSPKYPESYPPNSDCQWTIHVDENSQVAI EFVYFHLEQHKECIYDRLILTEGISKNSKKDGKEMSETFCGLIEKKT-IVSKTNQISLRF FSDNSVQKTGFELRFTKELNECAT---DKNICHHYCVNTVGGFKCACRVGYSLSS-NGFS CDSTCGGYLKASNGSISSPNFPE-MYPNSKTCIWEIEAPDGYHIFLNFTKFNVEGM---K TECAYDYVKI----GDSE-----KLCGEYHEALLFTTPRNRVRIEFSSDSSVERDGFFAN FIADF----DECQNDNAGCEHTCQNRLGSYVCTCNPGYILAEDKHNC----KEGSCFFEV ------------NAPAGDINSPNYPNDY----------------------------PKGQ NCSWHFVTTPGHR-----------------LMLTFSSFQVEEHAQCKYDAVSVYDGGDGS AQL-----------------AGVFCGLAPPPLLLSSSNELYLTFSSDASVSRRGFQAHYT S---------LCGGRLTAESTPGHIYSHATFSDSKYGKNQDCSWIVRAKSPGRGVRIQFS TFNIESEEGCQYDYIEIYDGPE---ATLERLVGRFCGDTSPEVITSTGPELLLIMHTDN- ---AEEEKGFVAEYREAPRSSSTKRTFVSKTRH--------------------------- ---------------------------------------------SPLEEP--------- ---------------------------------------IHDRNE--------------- ----------------------------------------------------
BMGE Cleaned alignment of selected proteins >sp|Q15113|PCOC1_HUMAN Procollagen C-endopeptidase enhancer 1 OS=Homo sapiens OX=9606 GN=PCOLCE PE=1 SV=2 MLPAATASLTACA-LLPFLCGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLEGQG-KRGTEPKV--KTEESPSAPDAP--TCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQPPMKKGVSYLLMGQVEENRGPVLPPESFVVLHRPQILTNLSKCPSQ >tr|B3DJG2|B3DJG2_DANRE Procollagen C-endopeptidase enhancer b OS=Danio rerio OX=7955 GN=pcolceb PE=2 SV=1 MWAAVRVCLGLLFLGLGFLCGGHLVTDSGFVASEGFPSHYKANSKCTWYITVPEGHVVMLQFRIFDLEADPTCRYDYVDVYNGHSYTVQKLGRFCGTFRPGALISTSNTMMLEMASDSSTGGRGFLAYFSGGKPHVDEHQFCGGRLTKPQGSVKTPNWPESDYPAGISCSWHISVESNMVIEVKFEKLDLELDTYCRYDYVALFNGGETDDSRRIGKFCGDTVPDAVVTNGNELLVHFVSDLSVTAAGFMAHYRSVPTADLKPPSRPFKKPTPKPRPQPKSAGNPLCSLPCKRIGTMVTRFCPSHFVLTGKVTSLSPGSQGSAEVEVSVIKVYKAGRLQLRKRGPSTSATLTATCSKPALRKGVNYVLMGHVNDDGLGILNPSSFALQHKARALANLAAC--- >tr|F1QUX0|F1QUX0_DANRE Procollagen C-endopeptidase enhancer a OS=Danio rerio OX=7955 GN=pcolcea PE=4 SV=1 LLDMEHLTWLLLSLSFGFNCGGDLVGDSGFVGSEGFPSFYKPNSKCTWYITVPEGNVVMLSFRIFDLEADPLCRYDYVDVYNGHSNMVQKLGRFCGTFRPGALISTSNTMMVEMVSDSGTGGRGFVAYFNGGKPHVDEHQFCGGKLTKSQGTIKTPNWPEKNYPPGISCSWLITVEPEMVIEVKFDKFDLESDTYCRFDYVAFFNGGEKDDSRRIGKYCGYTAPQNIVTNSNVLLVQFVSDLSVTSDGFMASYTSIPSAGG-VVTTEAIKPEPE-RPRPATETNPLCAKACKRDGTIKTSFCASEFVITGTLTALTAGPRGSMQGTVSLIKAYKTGRLTITQAGETMSVKLMMPCKKPLLRRGQNYILMGEVDDEGRGVLNPGTFTALYKAKMLTNINPC--- >NP_032814.2 procollagen C-endopeptidase enhancer 1 precursor [Mus musculus] MLPAALTSLLAW--VLPFLCGGDVTGESGYVASEGFPNLYPPNKKCIWTITVPEGQTVSLSFRVFDMELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPVVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRMEKAQGTLTTPNWPESDYPPGISCSWHIIAPSNQVIMLTFGKFDVEPDTYCRYDSVSVFNGAVSDDSKRLGKFCGDKAPSPISSEGNELLVQFVSDLSVTADGFSASYRTLKESALKTGTGPKVSPATQATPVAPAAPSITCPKQYKRSGTLQSNFCSSSLVVTGTVKTMVRGPGEGLTVTVSLLGVYKTGGLDLPSPPSGTSLKLYVPCRQPPMKKGASYLLMGQVEENRGPILPPESFVVLYRSQILNNLSKCPSQ >KAB0349382.1 hypothetical protein FD754_014239 [Muntiacus muntjak] MLPAATASLTAWALLLPFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSATYRTQGGPGEKPGAGPKVEPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQPPMKKGISYLLMGQVDKNRGPILPPESFVVLHRPQILTNLGKCPSK >KAB0384410.1 hypothetical protein FD755_006327 [Muntiacus reevesi] MLPAATASLTAWALLLPFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSATYRTQGGPGEKPGAGPKVEPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQPPMKKGISYLLMGQVDKNRGPILPPESFVVLHRPQILTNLGKCPSK >XP_043310674.1 procollagen C-endopeptidase enhancer 1 isoform X2 [Cervus canadensis] MLPAATASLTAWALLLPFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSATYRTQGGPGEKPGAGPKVAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKAGGLDLPAPPTDTLLKFYVPCKQPPMKKGISYLLMGQVDKNRGPILPPESFVVLHRPQILTNLGKCPSK >OWK11217.1 PCOLCE [Cervus elaphus hippelaphus] GLAEATSDLLASP-ALPFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSATYRTQGGPGEKPGAGPKVAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKAGGLDLPAPPTDTLLKFYVPCKQPPMKKGISYLLMGQVDKNRGPILPPESFVVLHRPQILTNLGKCPSK >KAF4015881.1 hypothetical protein G4228_007241 [Cervus hanglu yarkandensis] MLPASTASLTAWALLLPFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSATYRTQGGPGEKPGAGPKVAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKAGGLDLPSPPTDTLLKFYVPCKQPPMKK------VFRADQRSG----PRQLLTLYNPVLRFRVLTAPAK >NP_001082711.1 uncharacterized protein LOC398671 precursor [Xenopus laevis] --------LLCLSLVLGFLCGGDITGDSGFIGSEGFPNYYPPNKKCVWNITVPDGHVVMLTFRLLDMEADPSCRYDYLNIYNGHFETGQRLARVCGTFRPGALLSTGPQMMLEMVTDDGTAGRGFLAWYSAGSTQPSESQLCGGKLEKPQGSINTPNWPENNYPSGISCSWHIVAPKEKVVELSFGKFDVEGDSYCRFDYLAVFNGGETDNTRLIGKFCGDSSPKTIYSDGNEMLVQFVSDLSVTADGFAVNYRMRST-----------KPTK--LPKSPSSSAVKCPQKCRKTGTLGSHYCANQFVVTGTVNSLTQGDEKSLLATVTIIKTFKVEGLSIQESGKTMSIKVINECPKPILKKGSSYLFMGEVNAEGQGRIVPESFVIAHKAQILTAISPC--- >XP_021147809.1 procollagen C-endopeptidase enhancer 2 [Columba livia] --------CADTPLCPGFACGGVVSGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLSFRYLDLESDNLCRYDFVDIYNGHA-NGQRIGRFCGTVKPGALISNSNKMLVQMTSDANTAGSGFIAKFSAAEPHERGDQYCGGRLEKPSGSFQTPNWPERDYPAGVTCSWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPILSERNELLIQFLSDLSLTADGFIGHYKFRTT------------------------TVALCQQKCKRSGTIESNYCSSNFVITGTVITAVTR-AGSLHATISIINVYKEGNLAIQQAGKNMSAKIIVVCKQPLIRRGLNYIIMGQVEEDGRGKVFPNSFVMSFKTKILNALKTCYN- >XP_015816628.1 PREDICTED: procollagen C-endopeptidase enhancer 2-like [Nothobranchius furzeri] ----MSPCLLFLSLTSGFYCGGDLVAESGFVGSEGFPNFYKPNSKCIWRITVPEGNVVTLSFRIFDLEADSQCRYDYLEVYNGHSNGVQKLGRFCGTFRPGALISSTNTMMLEMRSDGETQGRGFVAYFSGAKPYVNDEQFCGGKMTKSQGEIKTPNWPDNKYPPGISCSWIITVEPNQVIQVKFEKFILEADTYCRFDYVLFFNGGERDDSRLIGRYCGDQTPEPIITSGNMLLVHFVSDFSVPSDGFFAYYTSIATVESRPVVLRITRPNGK-RP---VLQNPLCAKACKRTGTIKTAFCSSEFVITGKVMSLTPGPRGTLHIKVSLIKAYKAGRLTITQVGETMAVKLVSQCKKPLLRRGANHIIMGQVDEEGRGTLAPGAFTAPYKTKLLMNINPC--- >XP_040535317.1 procollagen C-endopeptidase enhancer 2 isoform X2 [Gallus gallus] ------------SLSE-FTCGGVVSGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLSFRYLDLESDNLCRYDFVDIYSGHA-NGQRIGRFCGTVKPGALVSSSNKMLVQMTSDANTAGNGFIAKFSAAEPHERGDQYCGGRLEKPSGSFQTPNWPERDYPAGVTCSWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPIVSEKNELFIQFLSDLSLTADGFIGHYKFRTT------------------------TVALCQQKCKRSGTPESNYCSSNFVITGTVISTTTR-AGSLHATISIINVYKEGNLAIQQAGKNMSAKIIVVCKQPLLRRGLNYIIMGQVEEDGRGKIFPNSFVMSFKTKILNSLKTCYN- >XP_031410927.1 procollagen C-endopeptidase enhancer 2 [Meleagris gallopavo] LLTAAVRSAAASSL---FTCGGVVSGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLSFRYLDLESDNLCRYDFVDIYSGHT-NGQRIGRFCGTVKPGALVSSSNKMLVQMTSDANTAGSGFIAKFSAAEPHERGDQYCGGRLEKPSGSFQTPNWPERDYPAGVTCSWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEINDAKRIGKYCGDSPPAPILSEKNELFIQFLSDLSLTADGFIGHYKFRTT------------------------TVALCQQKCKRSGTLESNYCSSNFVITGTVISTTTR-AGSLHATISIINVYKEGNLAIQQAGKNMSAKIIVICKQPLIRRGLNYIIMGQVEEDGRGKIFPNSFVMSFKTKILNALKTCYN- >XP_030253492.1 procollagen C-endopeptidase enhancer 2 isoform X2 [Sparus aurata] MWRTC---FCAWSLLF-FTCGGNITGESGVIGSQGYPGVYPPNTKCVWRITVPEGKVVVLSFRSIDLESDNLCRYDYVDVYSGHV-SGQRLGRFCGTFKPGALVSTGNKMLMQMVSDANTAGSGFLAVFSAAHPHERGDQYCGGRLDRPSGTFKTPNWPEKDYPAGVTCSWHIVAPKNQIIEVKFEKFDVERDNYCRYDHVSIFNGAEINDAKRIGKYCGDSPPAPVFSDGNQLLIQFLSDLSLTADGFIGHYKFRTT----------------------KYSVALCQQKCKRRGTLESNYCSSNFVITGTVITAVMR-GGSMFATVSIINVYKEGSLAIQQAGKTMSTKIIILCKKPFIRRGLNYVFMGQVDEDGKGKIAPHHFVMAFKTKGLNVLKRC--- >XP_004081148.3 procollagen C-endopeptidase enhancer 2 [Oryzias latipes] MWRAC---FCAWSLLL-FTCGGNITGESGVIGSQGYPGVYPPNTKCVWRITVPEGKVVVLSFRTIDLENDNLCRYDYVDVYSGHI-SAQRLGRFCGTFKPGSLVSTGNKMLLQMVSDANTAGSGFLAVFSAAHPHERGDQYCGGRLVKPNGTFKTPNWPEKDYPAGVTCSWHIVAPKNQIIEVKFEKFDVERDNYCRYDHVSIFNGAEINDARRIGKYCGDSPPAPVFSEGNQVLIQFLSDLSLTADGFIGHYKFRTT----------------------KYSVALCQQKCKRRGTLHSNYCSSNFVITGTVITAMMK-GGSMYATVSIINVYKEGNLAIQQAGKTMSTKIIILCKKPFIRRGLNYIFMGQVDEEGRGKIAPQHFVMAFKTKGLNVLKQC--- >NP_062110.1 procollagen C-endopeptidase enhancer 1 precursor [Rattus norvegicus] MLPAALTSLLAW--VLPFLCGGDVTGESGYVASEGFPNLYPPNKKCIWTITVPEGQTVSLSFRVFDMELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPVVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRMEKAQGTLTTPNWPESDYPPGISCSWHIIAPSNQVIMLTFGKFDVEPDTYCRYDSVSVFNGAVSDDSKRLGKFCGDKAPSPISSEGNELLVQFVSDLSVTADGFSASYRTLKESAPKTGTGPKVSPATQATPVAPDAPSITCPKQYKRSGTLQSNFCSSSLVVTGTVKAMVRGPGEGLTVTVSLLGVYKTGDLDLPSPASGTSLKFYVPCKQPPMKKGASYLLMGQVEENRGPILPPESFVVLYRPQILSNLSKCPSQ >XP_016801667.1 procollagen C-endopeptidase enhancer 1 [Pan troglodytes] MLPAATASLTACA-LLPFLCGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVALRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLEGQG-KPGTEPKV--KTEESPSAPDAP--TCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQPPMKKGVSYLLMGQVEENRGPVLPPESFVVLHRPQILTNLSKCPSQ >XP_038394384.1 procollagen C-endopeptidase enhancer 1 isoform X1 [Canis lupus familiaris] MLPAATASLTAWA-LLPFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTADEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDTYCRYDSVSVFNGAVSDDAKRLGKFCGDTAPGPISSEGNELLVQFVSDLSVTADGFSASYKTLEGQAR--------SSEAQATPEAPNVPNVSCPKQCRRTGTLQSNFCSSSLVVTATVKSMVRGPGEGLTVTVSLIGAYKTGGLDLPSPITDTPLKFYVPCKQPPMKKGASYLMMGQVEENRGPILPAESFVVLYRPQILTNLSKCPSQ >NP_001039353.1 procollagen C-endopeptidase enhancer 1 precursor [Bos taurus] MLPAATASLTAWALLLPFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPVVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSASYRTQGVPGEKPGAGPKVAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQPPMKKGISYLLMGQVDKNRGPILPPESFVVLHRPQILTNLSKCPSK >XP_017198071.1 PREDICTED: procollagen C-endopeptidase enhancer 1 [Oryctolagus cuniculus] MLPAATASLTAWA-LLPFLCGGDVTGDSGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTADEGTGGRGFLLWYSGRATSGTEHQFCGGRMEKEQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFGKFDLEPDTYCRYNSVSVFNGAVSDDAKRLGKFCGDTAPGPISSEGNELLVQFVSDLSVTADGFSASYRILQGPAQKPGVGPKVPPEAKTPPQDPDVPSIPCPKQCQRTGTMQSNFCTSNLVVTGTVKSIVRGPGEGLWVTVSLIGAYKTGGLELPSPPTDASLKFYVPCKHRPLKKGASYLLMGQVKENGVPVLPPDSFVVLYRPQILTNLSKCPSQ >XP_009240915.1 procollagen C-endopeptidase enhancer 1 isoform X1 [Pongo abelii] MLPAATASLTAWA-LLPFLCGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTADEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTL-GQG-KPGTEPKV--KTEETPSAPDAP--TCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQPPMKKGVSYLLMGQVEENRGPVLPPESFVVLHRPQILTNLSKCPSQ >XP_003354522.1 procollagen C-endopeptidase enhancer 1 [Sus scrofa] MLPAATASLTAWA-LLPFLCGGDVTGESGYLASEGFPNLYPPNKECIWTITVPESQTVSLSFRVFDLELHPSCRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGAVSDDAKRLGKFCGDKAPGPISSEGNELLVQFVSDLSVTADGFSASYRTLKAPAQKPGAGPKVAPKAEATPAGSDGPSVPCPKQCRRTGTLQSNFCNSNLVVTATVKSMVRGPGEGLTVTVSLIGVYKTGGLDLPSPPTDTSLKFYAPCKQPPMKKGTSYLMMGQVDENRGPILPPESFVVLYRPQILTNLARCPSQ >XP_003812960.2 procollagen C-endopeptidase enhancer 1 [Pan paniscus] MLPAATASLTACA-LLPFLCGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVALRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLEGQG-KPGTEPKV--KTEESPSAPDAP--TCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQPPMKKGVSYLLMGQVEENRGPVLPPESFVVLHRPQILTNLSKCPSQ >XP_006942048.3 procollagen C-endopeptidase enhancer 1 isoform X1 [Felis catus] MLPAATASLTAWA-LLPFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDFELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTADEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDTYCRYDSVSVFNGAASDDAKRLGKFCGDTAPGTISSEGNELLVQFVSDLSVTADGFSASYKTLEAQAQ--------SSEAQATPGGPDVPSVPCPKQCRRTGTLQSNFCTSNLVVTATVKSMVRGPGEGLTVTVSLIGAYKTGGLDLPSPLTDTPLKFYVPCKQPPMKKGVSYLMMGQVEENRGPTLPPESFVVLYRSQILTNLSKCPSQ >XP_004021061.1 procollagen C-endopeptidase enhancer 1 [Ovis aries] MLPAATASLTAWALLLPFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSASYRIQEGPGEKPGAGPKVAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKTGGLDLPSPPTDSLLKFYVPCKQPPMKKGISYLLMGQMDKNRGPILPPESFVVLHRPQILTNLSKCPSK >XP_004045959.1 procollagen C-endopeptidase enhancer 1 [Gorilla gorilla gorilla] MLPAATASLTACA-LLPFLCGGDVKGESGYVASEGFPNLYPPNKECIWIITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLEGQG-KPGTEPKV--KTEETPSAPDAP--TCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAVTVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQPPMKKGVSYLLMGQVEENRGPVLPPESFVVLHRPQILTNLSKCPSQ >XP_017895868.1 PREDICTED: procollagen C-endopeptidase enhancer 1 [Capra hircus] MLPAATASLTAWALLLPFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSASYRTQEGPGEKPGAGPKVAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNVTGVYKTGGLDLPSPPTDTLLKFYVPCKQPPMKKGISYLLMGQMDKNRGPILPPESFVVLHRPQILTNLSKCPSK >XP_019333518.1 PREDICTED: procollagen C-endopeptidase enhancer 1 isoform X1 [Alligator mississippiensis] MSPGPG--LWLCALSRPFLCGGEHSGDAGYVASEGFPNFYPPNSDCTWTITVPEGQVVMLTFRVLDLEPDSSCRHDFLEVLSG----AQRLARVCGTLRPGTILTPGRRVQLRMVSDEATSGRGFLLWFSGALPHVNDQQFCGGRLEKPQGTIKTPNWPESDYPAGISCSWHIIAPPGKVIELTWGKFDVEADTYCRYDYVSVFQGGQSDDARRVGRFCGDTSPVPIISEGRELLVQFVSDLSVTADGFAATYAARRGPSPEPGTGKGKAPEGQ-LPSTVPTGPIACPKTCRRTGTLQSNFCASDFVLTGTVKAVTRGPGEGVTATVAVVTVYKAGALALPQPHKGASLRLAVPCRQPQLKKGASYILMGQLDTGG-PWLPPESFVVQFRPQVLTNLSSCLPR >XP_020731411.1 procollagen C-endopeptidase enhancer 1 [Odocoileus virginianus texanus] MLPAATASLTAWALLLPFLCGGDVTGESGYVASEGFPNLYPPNKECIWTITVPKSQTVSLSFRVFDLEQHPSCRYDALEIFAGSGTSGQQLGRFCGTFRPAPLVASGNQVTLRMRSDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVISLTFGKFDLEPDSYCRYDSVSVFNGPVSDDAKRLGKFCGDTVPGSITSEGNELLVQFVSDLSVTADGFSATYRTQGGPGEKPGAGPKVAPKAEATPVGPDAPSVTCPKQCRRTGTLQSHFCNSDLVVTGMIKSMVRGPGEGLTATVNITGVYKTGGLDLPSPPTDTLLKFYVPCKQPPMKKGISYLLMGQVDKNRGPILPPESFVVLHRPQILINLGKCPSK >XP_040202913.1 procollagen C-endopeptidase enhancer 1 [Rana temporaria] --------LLALSLCLGFLCGGELTGDSGYVASEGFPSHYPHNKKCTWKITVPDGNIVILSFRLLDMEADPSCRYDYLNIYNGHSESSQRLARVCGTFRPGTIMSTGPQMMLEMGSDEETGGRGFIAWYSAGAPALNENLFCGGKMEKPQGSITSPNWPKSNYPSGITCSWHIVAPKDQVIELVFGKFDVEEDSYCRYDYLAVFNGGQMDNNHQIGKYCGDTPPKTVYSEGNEMLVQFISDLSVTAGGFDVTYRMKSK-----------KPTTPKKPRPTAGSPAKCPEKCRKTGTLGAHYCANQFVLTGTVKTLTKGEAGTLLASINIIQTYKTEGLTIQEAEKTTSVQIVNECPRPILKKGASYLFMGLVDGEGRGRIVGDSFVIAYRAQILTNVAPC--S >XP_039272807.1 bone morphogenetic protein 1-like [Styela clava] MRRAATARQTCITFIERAVCGGTIRKESGQIQSPNYPDDYRPSKECIWKVVVDEGFRVGLSFQAFEVERHDTCSYDYLEVRDGPTADSDLIGRFCGYDKPEDVKSTSNTLWIKFVSDGSVNKAGFAASFFKEIDECECEAACGGSVTNLDGYITSPNWPN-EYPTNKKCVWQIVAPPQHKISIQFEKFELEGNEVCKYDYVEIRSGLSDDA-KFHGRFCGLELPPVIRSTINEMSLAFKSDDTVSKRGFKIKFFSDNGGCEKEAGCKHDKECTWLTPGHRAYDHLELYDGSDSDQTVLGRYCGSKFIKFFSDASVQKRGGGNLNASTRSKDLFSHPQYGDNNYISGQECDWIITADTTIMSTSGSLLLRFHSDD----TINKKGFHARYSSEDISESSGRRI- >XP_038060665.1 bone morphogenetic protein 1 homolog isoform X2 [Patiria miniata] VARAVTSRYTCITFVERAVCGGNISKESGMLQSPNYPDDYRPDKSCVWYLTMPEGFQVGLNFQSFEVERHDNCIYDYVEVRDGHEDDSPLIGKYCGYLMPEDIKSSSNKLRVKFVSDGTVNKGGFSADFFKEDDECSCEVACGGFLTSLQGNITSPSYPD-LYPRDKNCVWHLVAPSLYRISLQFLSFELEGNDVCKYDYVEVRSGLTEVG-DLHGKFCGDDIPDTITSRYNNMRIEFKSDSTVSRPGFFAMFFADNGDCQKESGCRHDKECTWHTPGHKAYDHVVIYDGDSSEGHLLGRFCGTRYITFFSDASVSRRGGGVLQADYVSQKLYSHADYGDNNYGSQEDCEWTILAPQDIISQGENLRLIFRSDD----TISKKGFYAEYQI------------ >XP_030834881.1 bone morphogenetic protein 1 homolog isoform X1 [Strongylocentrotus purpuratus] HVRAVTARYTCITFVERAICGGHIERESGTLQSPNYPDDYHPSKECVWLITMPANYTVGLSFQSFEIERHETCIYDYVEVRDGHEDTSPLIGRYCGYFIPDDIKSTGNKMMVTFVSDGSVNKGGFSADFFKEKDECACEVACGGLFTGLRGNISSPSYPE-PYPRDKNCVWQIVAPSNYRISLQFITFDLEGNEVCKYDYVDVRSGLNEEG-TLHGKFCGNEIPETITSRFNNLRIDFRSDNTVAKEGFFANFFADNGGCQKESGCRREKECTWHNPGHKTYDRVQVFDGDSDEGQVLGRYCGATFIRFYSDASVSRSGGGRLEAELSAQRLYSHADYGDQNYENQESCEWTIVSPDDIVSSGDSLMITFSSDD----TINKKGFLAIFKLELLEGAGEEEIY >XP_031568191.1 prostasin-like [Actinia tenebrosa] --------VTIVGLVQSSNCGSNLQGKTGEVTSPGFPSPYPTGSTCVWTIRVDSKSAIXLNIKEMDIERSKKCRYDSLTMYDGANSKGPELVHLCGSKKPKTIRSSGNSLYIVFTSDDADTGKGFRATWKAVS----RNIKCGGKFTNLTGDISSPHFPN-NYPANVDCEWIITVPITHSLTLSFEIFNVEQSAKCSYDNVEIWEGTKKNS-PSLGRFCGTNSPGVINAQGTTLRIKLHSDESDTAQGFRAVWTSRTGG--KAGAWPWQKDKTMYLGEHLTTDNDLALIKLDKPATLTGTLCTISKVLMQAKVPIVSRDGGLRQGGVDSCQGDSGGPFVCRNPENPKQWSLVGVTSW---ARALKYGVYANVRK----XLPWINLLTGNMPPGSTVNTSVLTL >NP_001287510.1 tolkin, isoform C [Drosophila melanogaster] VARAVTAKSTCIKFVERVVCGGELSVDVGRLESPNYPLDYLPNKECVWKITVPESYQVALKFQSFEVENHDSCVYDYVEVRDGPGQDAPLIGVFCGYKPPPNMKSSGNSMYVKFVSDTSVQKAGFSAVFMKEVDECECEDACGGVIEYPNGTITSPSFPE-MYPLLKECIWEIVAPPKHRISLNFTHFDLEGTSDCGYDSVTVYSKLGENRLKRIGTFCGSSIPPTATSESNALRLEFHSDKSIQRSGFAAVFFTDNGGCQKEGECKYEADCVWHTPGHRTYDNVAVYDGESESSSVLGRFCGDKYMVLKTDKNKQKNGGGYLRATSQVQQFYSHARFGNQDYDDGMDCEWTIAAPDDINSMTHSLLVRFKTDG----SVPMKGFSASYVASGEYDHSDVENS >CAE1240683.1 tok [Sepia pharaonis] TRRAATARHTCITFVERAICGGVINKSRGTLTSPNSPDDYRANQECVWRITVPKAYLVGLMFQSFEIENHDNCVYDYLEIRDGPDETSPSLGKFCGYKVPEDIKSSGNQLYVKFVSDGSVQKAGFSATFTEEYNECLCEDACGGYISIENGTFQSPSFPD-LYPTNKYCVWQIVAPKQHRITLNFSYFDLEGNQDCEYDSVRVSNGLNSDT-KAIGIFCGSTLPDSITSSENSLRIEFSSDNSVQKTGFNATFFTDNGGCQKEGGCKHQKDCVWTTDGHRTYDHIEIFDGTSTNSRSLGRFCGNKFMIFYSDASVQRKGGGHLLAKTEPKFIYSHAKYGDQNYDNAADCDWIIEAEDPVTSSGRILTIRFVTDD----TVNWKGFSLTYRLQS----TGETQE >KAG9429998.1 tolloid-like protein 1 isoform X1 [Apis mellifera carnica] ARRAATARFTCVKFVERAVCGGEIELETGHLESPNYPDGYQSSKECVWKLSVPQNFQVALKFQSFEIENHDNCVYDYVEVRDGHNADSPLIGVYCGYKIPPDIKSTGNKLLVKFVSDGSVQKAGFSATFMKEFDECVCEDACGGVFEDSNGTITSPSFPV-TYPGNKDCVWEIIAPPQYRITLNFTHFDLEGTQECEYDSVEVSSKLGDDILRKHGVFCGSRLPSLITSEGNSMRVTFTSDNSIQKTGFAAVFFTDNGGCQKEGGCKYEKDCVWHKPGHRNYDHIAIYDGDSPDSHVLGKFCGTKYMVFKSDASVQRKGGGHLVATNEIRHLYSHARYGVHNYDHRTDCDWAIEAPPDFISINEALLVRFRTDD----TISNKGFMALFVAQDSGENYSEDED >NP_001360030.1 Zinc metalloproteinase nas-39 [Caenorhabditis elegans] VSRAATAKFTCVSFVPRAICGGPIYANEGVIHSPKYPESYPPNSDCQWTIHVDENSQVAIEFVYFHLEQHKECIYDRLILTEGISKNSKKDGKFCGLIEKKTIVSKTNQISLRFFSDNSVQKTGFELRFTKELNECACDSTCGGYLKASNGSISSPNFPE-MYPNSKTCIWEIEAPDGYHIFLNFTKFNVEGMTECAYDYVKI----GDSE-----KLCGEYHEALLTTPRNRVRIEFSSDSSVERDGFFANFIADNAGCEKEGSCFFEQNCSWHTPGHRKYDAVSVYDGGDGSAQLAGVFCGLAYLTFSSDASVSRRGGGRLTAESTPGHIYSHATFSDSKYGKNQDCSWIVRAKSVITSTGPELLLIMHTDN----AEEEKGFVAEYRESSSTKRTSKTRH
PhyML tree of selected proteins (((XP_039272807_1_bone_morphogenetic_protein_1_like__Styela_clava_:0.37284074,(XP_030834881_1_bone_morphogenetic_protein_1_homolog_isoform_X1__Strongylocentrotus_purpuratus_:0.23817051,XP_038060665_1_bone_morphogenetic_protein_1_homolog_isoform_X2__Patiria_miniata_:0.17229484):0.21031565):0.16225135,(CAE1240683_1_tok__Sepia_pharaonis_:0.28961841,(KAG9429998_1_tolloid_like_protein_1_isoform_X1__Apis_mellifera_carnica_:0.19451344,NP_001287510_1_tolkin__isoform_C__Drosophila_melanogaster_:0.36812617):0.13589329):0.08065792):0.20514209,NP_001360030_1_Zinc_metalloproteinase_nas_39__Caenorhabditis_elegans_:0.77002076,(XP_031568191_1_prostasin_like__Actinia_tenebrosa_:1.72255003,((((tr_B3DJG2_B3DJG2_DANRE_Procollagen_C_endopeptidase_enhancer_b_OS_Danio_rerio_OX_7955_GN_pcolceb_PE_2_SV_1:0.29638945,(XP_015816628_1_PREDICTED__procollagen_C_endopeptidase_enhancer_2_like__Nothobranchius_furzeri_:0.28139297,tr_F1QUX0_F1QUX0_DANRE_Procollagen_C_endopeptidase_enhancer_a_OS_Danio_rerio_OX_7955_GN_pcolcea_PE_4_SV_1:0.13764742):0.11296678):0.22010251,((XP_030253492_1_procollagen_C_endopeptidase_enhancer_2_isoform_X2__Sparus_aurata_:0.02898766,XP_004081148_3_procollagen_C_endopeptidase_enhancer_2__Oryzias_latipes_:0.03960544):0.11724395,(XP_021147809_1_procollagen_C_endopeptidase_enhancer_2__Columba_livia_:0.02829463,(XP_040535317_1_procollagen_C_endopeptidase_enhancer_2_isoform_X2__Gallus_gallus_:0.0168432,XP_031410927_1_procollagen_C_endopeptidase_enhancer_2__Meleagris_gallopavo_:0.00584265):0.01712445):0.1210579):0.37471582):0.079772,(XP_040202913_1_procollagen_C_endopeptidase_enhancer_1__Rana_temporaria_:0.22180714,NP_001082711_1_uncharacterized_protein_LOC398671_precursor__Xenopus_laevis_:0.15533493):0.22093434):0.08689082,(XP_019333518_1_PREDICTED__procollagen_C_endopeptidase_enhancer_1_isoform_X1__Alligator_mississippiensis_:0.30536311,(((XP_003354522_1_procollagen_C_endopeptidase_enhancer_1__Sus_scrofa_:0.02908174,((XP_017895868_1_PREDICTED__procollagen_C_endopeptidase_enhancer_1__Capra_hircus_:0.00000001,XP_004021061_1_procollagen_C_endopeptidase_enhancer_1__Ovis_aries_:0.00506388):0.00289498,(NP_001039353_1_procollagen_C_endopeptidase_enhancer_1_precursor__Bos_taurus_:0.00512446,(XP_020731411_1_procollagen_C_endopeptidase_enhancer_1__Odocoileus_virginianus_texanus_:0.0051018,((KAB0349382_1_hypothetical_protein_FD754_014239__Muntiacus_muntjak_:0.00000001,KAB0384410_1_hypothetical_protein_FD755_006327__Muntiacus_reevesi_:0.00000001):0.00254242,(KAF4015881_1_hypothetical_protein_G4228_007241__Cervus_hanglu_yarkandensis_:0.07198387,(OWK11217_1_PCOLCE__Cervus_elaphus_hippelaphus_:0.02350677,XP_043310674_1_procollagen_C_endopeptidase_enhancer_1_isoform_X2__Cervus_canadensis_:0.00000001):0.00253141):0.00255569):0.00000001):0.0050755):0.00222323):0.07740923):0.02555338,(XP_017198071_1_PREDICTED__procollagen_C_endopeptidase_enhancer_1__Oryctolagus_cuniculus_:0.08598413,((XP_009240915_1_procollagen_C_endopeptidase_enhancer_1_isoform_X1__Pongo_abelii_:0.00000001,(XP_004045959_1_procollagen_C_endopeptidase_enhancer_1__Gorilla_gorilla_gorilla_:0.00258974,(sp_Q15113_PCOC1_HUMAN_Procollagen_C_endopeptidase_enhancer_1_OS_Homo_sapiens_OX_9606_GN_PCOLCE_PE_1_SV_2:0.0025783,(XP_016801667_1_procollagen_C_endopeptidase_enhancer_1__Pan_troglodytes_:0.00000001,XP_003812960_2_procollagen_C_endopeptidase_enhancer_1__Pan_paniscus_:0.00000001):0.00258009):0.00256383):0.00517392):0.06547245,(XP_038394384_1_procollagen_C_endopeptidase_enhancer_1_isoform_X1__Canis_lupus_familiaris_:0.01936885,XP_006942048_3_procollagen_C_endopeptidase_enhancer_1_isoform_X1__Felis_catus_:0.02796422):0.0128723):0.01526602):0.00792446):0.01995551,(NP_032814_2_procollagen_C_endopeptidase_enhancer_1_precursor__Mus_musculus_:0.01653936,NP_062110_1_procollagen_C_endopeptidase_enhancer_1_precursor__Rattus_norvegicus_:0.006593):0.07376065):0.26589018):0.16330869):0.9855207):1.02548833);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)