PB0047

DATABASE

Click here to access PB0047 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0047	P02652	Apolipoprotein A-II	APOA2	Apo-AII, ApoA-II, apoAII, apolipoprotein A2	Homo_sapiens	May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.

Domains

Gene Ontology

PF04711 (ApoA-II)

GO:0120020 (contributes to) cholesterol transfer activity GO:0005102 (enables) signaling receptor binding GO:0005319 (enables) lipid transporter activity GO:0005515 (enables) protein binding GO:0005543 (enables) phospholipid binding GO:0008035 (enables) high-density lipoprotein particle binding GO:0008289 (enables) lipid binding GO:0015485 (enables) cholesterol binding GO:0031072 (enables) heat shock protein binding GO:0031210 (enables) phosphatidylcholine binding GO:0034190 (enables) apolipoprotein receptor binding GO:0042803 (enables) protein homodimerization activity GO:0046982 (enables) protein heterodimerization activity GO:0055102 (enables) lipase inhibitor activity GO:0060228 (enables) phosphatidylcholine-sterol O-acyltransferase activator activity GO:0070653 (enables) high-density lipoprotein particle receptor binding GO:0002526 (involved in) acute inflammatory response GO:0002719 (involved in) negative regulation of cytokine production involved in immune response GO:0006641 (involved in) triglyceride metabolic process GO:0006656 (involved in) phosphatidylcholine biosynthetic process GO:0006869 (involved in) lipid transport GO:0008203 (involved in) cholesterol metabolic process GO:0009395 (involved in) phospholipid catabolic process GO:0009410 (involved in) response to xenobiotic stimulus GO:0009749 (involved in) response to glucose GO:0010873 (involved in) positive regulation of cholesterol esterification GO:0010903 (involved in) negative regulation of very-low-density lipoprotein particle remodeling GO:0018158 (involved in) protein oxidation GO:0018206 (involved in) peptidyl-methionine modification GO:0030300 (involved in) regulation of intestinal cholesterol absorption GO:0030301 (involved in) cholesterol transport GO:0031100 (involved in) animal organ regeneration GO:0031647 (involved in) regulation of protein stability GO:0032375 (involved in) negative regulation of cholesterol transport GO:0032757 (involved in) positive regulation of interleukin-8 production GO:0033344 (involved in) cholesterol efflux GO:0033700 (involved in) phospholipid efflux GO:0034370 (involved in) triglyceride-rich lipoprotein particle remodeling GO:0034374 (involved in) low-density lipoprotein particle remodeling GO:0034375 (involved in) high-density lipoprotein particle remodeling GO:0034380 (involved in) high-density lipoprotein particle assembly GO:0034384 (involved in) high-density lipoprotein particle clearance GO:0042157 (involved in) lipoprotein metabolic process GO:0042632 (involved in) cholesterol homeostasis GO:0043627 (involved in) response to estrogen GO:0043691 (involved in) reverse cholesterol transport GO:0046340 (involved in) diacylglycerol catabolic process GO:0050766 (involved in) positive regulation of phagocytosis GO:0050821 (involved in) protein stabilization GO:0050995 (involved in) negative regulation of lipid catabolic process GO:0050996 (involved in) positive regulation of lipid catabolic process GO:0051384 (involved in) response to glucocorticoid GO:0060192 (involved in) negative regulation of lipase activity GO:0060621 (involved in) negative regulation of cholesterol import GO:0060695 (involved in) negative regulation of cholesterol transporter activity GO:0120009 (involved in) intermembrane lipid transfer GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005769 (located in) early endosome GO:0005788 (located in) endoplasmic reticulum lumen GO:0005829 (located in) cytosol GO:0070062 (located in) extracellular exosome GO:0072562 (located in) blood microparticle GO:0034361 (part of) very-low-density lipoprotein particle GO:0034364 (part of) high-density lipoprotein particle GO:0034366 (part of) spherical high-density lipoprotein particle GO:0042627 (part of) chylomicron

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P02652|APOA2_HUMAN Apolipoprotein A-II OS=Homo sapiens OX=9606 GN=APOA2 PE=1 SV=1 MKLLAATVLLLTICSLEGALVRRQAKEPCVESLVSQYFQTVTDYGKDLMEKVKSPELQAE AKSYFEKSKEQLTPLIKKAGTELVNFLSYFVELGTQPATQ >tr|B3DFP9|B3DFP9_DANRE Apolipoprotein A-II OS=Danio rerio OX=7955 GN=apoa2 PE=1 SV=1 MKLTFALILALQVSVCVWAQEWPVPDKELVDKYDGLRTVFIKRLVNAWEKIKTAVEPALE GSPTAGSLKDVVEELKKSPRVESFIKIAGGLASELEPVVDKARLNALGVYGHYFRPYVGA YLDSAINNVKPVLDTVLPQGN
Selected proteins from model organisms >NP_001634.1 apolipoprotein A-II preproprotein [Homo sapiens] MKLLAATVLLLTICSLEGALVRRQAKEPCVESLVSQYFQTVTDYGKDLMEKVKSPELQAEAKSYFEKSKE QLTPLIKKAGTELVNFLSYFVELGTQPATQ >XP_003999611.1 apolipoprotein A-II isoform X3 [Felis catus] MKLLAMAVLLLTVCSLEGALVRRQAEELSLQRLVSQYFQTVTDYGKDLVEKAKGPELQAQAKAYFEKTQEQLTPLVKKAG TDLINFLNSFMDLKTQPATQ >XP_043302053.1 apolipoprotein A-II [Cervus canadensis] MKLLALTVLLLTVCSLEGALVRRQAEEPDLQTLVSQYFQTVANYGKDLVEKAKGSELQTQAKAYFEKTQEELTPLFKKAG TDLLNFLSSFIDPKKEPAAH >KAB0357780.1 hypothetical protein FD754_001936 [Muntiacus muntjak] MKLLALTVLLLTVCSLEVCVCFCVCAGALVRRQAEEPDLQTLVSQYFQTVANYGKDLVEKAKGSELQTQAKAYFEKTQEE LTPLFKKAGTDLLNFLSSFIDPKKEPAAH >KAB0385150.1 hypothetical protein FD755_000106 [Muntiacus reevesi] MKLLALTVLLLTVCSLEECVCFCVCAGALVRRQTEEPDLQTLVSQYFQTVANYGKDLVEKAKGSELQTQAKAYFEKTQEE LTPLFKKAGTDLLNFLSSFIDPKKEPAAH >OWK05347.1 APOA2 [Cervus elaphus hippelaphus] MKLLALTVLLLTVCSLEGALVRRQAEEPDLQTLVSQYFQTVANYGKDLVEKAKGSELQTQAKQKTQEELTPLFKKAGTDL LNFLSSFIDPKKEPAAH >KAF4021120.1 hypothetical protein G4228_013757 [Cervus hanglu yarkandensis] MKLLALTVLLLTVCSLEGGCALVRRQAEEPDLQTLVSQYFQTVANYGKDLVEKAKGSELQTQAKQKTQEELTPLFKKAGT DLLNFLSSFIDPKKEPAAH >KYO19498.1 apolipoprotein A-II [Alligator mississippiensis] MTLRSRSAELARMKVLAMAMLLLCLSHLEGAVVRREAEAPAPNLLELYTHYIQRLSDVLTKELPEKMKAEEIKTQAKVYL EQANEQFAPIAKQLHNNLVELFTQLVETGKKAAEQ >XP_025050470.1 apolipoprotein A-II-like [Alligator sinensis] MKVLAMAMLLLCLSHLEGAVVRREAEAPAPNLLELYTHYIQRLSDVLTKELPEKMKAEEIKTQAKVYLEQANEQFAPIAK QLHNNLVELFTQLVETGKKATEQ >tr|B3DFP9|B3DFP9_DANRE Apolipoprotein A-II OS=Danio rerio OX=7955 GN=apoa2 PE=1 SV=1 MKLTFALILALQVSVCVWAQEWPVPDKELVDKYDGLRTVFIKRLVNAWEKIKTAVEPALE GSPTAGSLKDVVEELKKSPRVESFIKIAGGLASELEPVVDKARLNALGVYGHYFRPYVGA YLDSAINNVKPVLDTVLPQGN >NP_001292478.1 apolipoprotein A-II preproprotein [Mus musculus] MKLLAMVALLVTICSLEGALVKRQADGPDMQSLFTQYFQSMTDYGKDLMEKAKTSEIQSQAKAYFEKTHE QLTPLVRSAGTSLVNFFSSLMNLEEKPAPAAK >NP_037244.1 apolipoprotein A-II preproprotein [Rattus norvegicus] MKLLAMVALLVTICSLEGALVRRQAAETDVQTLFSQYLQSLTDYGKDLMEKAQPSEIQNQAKAYFQNAQE RLTPFVQRTGTNLMDFLSRLMSPEEKPAPAAK >NP_001008976.1 apolipoprotein A-II precursor [Pan troglodytes] MKLLAATVLLLTICSLEGALVRRQAKEPCVDNLVSQYFQTVTDYGKDLMEKVKSPELQAEAKSYFEKSKE QLTPLIKKAGTELVNFLSYFMELGTQPATQ >NP_001300728.1 apolipoprotein A-II precursor [Canis lupus familiaris] MKLLAVTVLLLVICSLEGAFVRRQAEEPNLQSLVSQYFQTVTDYGKDLMEKAKGPELQAQAKAYFEKTQE QLTPLVKKAGTDLLNFLSNFMDLKTQPATQ >NP_001039381.1 apolipoprotein A-II precursor [Bos taurus] MKLLALTVLLLTICGLEGALVRRQAEESNLQSLVSQYFQTVADYGKDLVEKAKGSELQTQAKAYFEKTQE ELTPFFKKAGTDLLNFLSSFIDPKKQPATR >NP_001173223.1 apolipoprotein A-II precursor [Sus scrofa] MKLLAIAVLLFTICSLEGALVRRQAEEPCLQSLVSQYLQTVTDFGKDLIEKAKGSELQTQAKTYFEKTQE QLTPLVKKAGTDIFNFLSSFIGLKTQPTAQ >NP_001158123.1 apolipoprotein A-II precursor [Pongo abelii] MKLLAATVLLLTICSLEGALVRRQAKEPCVESPVSQYFQTVTDYGKDLMEKVKSPELQAQAKSYFEKSKE QLTPLIKKAGTELVNFLNYFLEL >XP_002715298.1 PREDICTED: apolipoprotein A-II [Oryctolagus cuniculus] MKLLAMTVLLLTICSLEGALVRRQAEEQSLQSLVSQYLQTVTNYSKDLMEKAKAPELQAQAKAYFEKTQE QLTPLVKKAGTDLFNFLSNFMDLKTQPAAP >XP_003811880.1 apolipoprotein A-II [Pan paniscus] MKLLAATVLLLTICSLEGALVRRQAKEPCVDNLVSQYFQTVTDYGKDLMEKVKSPELQAEAKSYFEKSKE QLTPLIKKAGTELVNFLSYFMELGTQPATQ >XP_004002742.1 apolipoprotein A-II [Ovis aries] MKLLALTVLLLTICGLEGALVRRQAEEPNLQSLVSQYFQTVADYGKDLVEKAKGSELQTQAKAYFEKTQE ELTPLFKKAGTDLLNFLSSFIDPKKQPAAR >XP_004027815.1 apolipoprotein A-II [Gorilla gorilla gorilla] MKLLAATVLLLTICSLEGALVRRQAKEPCVESLVSQYFQTVTDYGKDLMEKVKSPELQAEAKSYFEKSKE QLTPLIKKAGTELVNFLSYFVELGTQPATQ >XP_005677218.2 PREDICTED: apolipoprotein A-II [Capra hircus] MKLLALTVLLLTICGLEGALVRRQAEEPNLQSLVSQYFQTVADYGKDLMEKAKGSELQTQAKAYFEKTQE ELTPLFKKAGTDLLNFLSSFIDPKKQPAAR >XP_020762724.1 apolipoprotein A-II [Odocoileus virginianus texanus] MKLLALTVLLLTICSLEGALVRRQAEEPDLQSLVSQYFQTVANYGKDLVEKAKGSELQTQAKAYFEKTQE ELTPLFKKAGTDLLNFLSSFIDPKKEPATN >XP_020565949.1 uncharacterized protein LOC101163028 [Oryzias latipes] MLIGTVPCYITLSRCELWVTDNSLPEKTVTSWVWSSSTSVMNAKYILALVLALQVSMSLCEIPAPSPELQSKYDSMKSTF IKRLENAYKKLQDAVSTSEQGQVTKELVDSVHNRPEFQAVVKVASGLGSEAAPIVDRARSSLLGLYEQYLRPHVGESLSS GIDHIKIYLDQVMPAE >XP_030250520.1 uncharacterized protein LOC115567819 isoform X2 [Sparus aurata] MHAKYALALILALQVSVSLCEIPDPPQELVDKYNEYKGTFYKRLLNLLSQAQTASGPMVEQASQDGRGQAVREYAETLQA KPEFQAFVKVATALGEEASPLVDKARLKLLGAYQAYLRPYVGEWLADTITEAKVYLDKVMPAE >XP_015805618.1 PREDICTED: uncharacterized protein LOC107379396 [Nothobranchius furzeri] MNAKLILALALVLQASVSFCEIPAPSQELVQKYESLRDTFYSRLRNAYSKLQTTVGENEQGQNAQNFIESLKDKPELQAI VKVASGLGAEARPLVDRARTSLLGLYEAYLRPHVGTGLSDTIDRIKVYLDEVMPAQ
Mafft alignment of selected proteins >NP_001634.1 apolipoprotein A-II preproprotein [Homo sapiens] -------------------------------------MKLLAATVLLLTICSLE------ ---G--ALVRRQAKEP--CVESLV----SQYFQTVTD----------------------- ----YGKDLMEKVKS-PELQAEAKSYFEKSKEQLTPLIKKAGTELVNFLSYFVEL----- -------------GTQPA--TQ >XP_003999611.1 apolipoprotein A-II isoform X3 [Felis catus] -------------------------------------MKLLAMAVLLLTVCSLE------ ---G--ALVRRQAEEL--SLQRLV----SQYFQTVTD----------------------- ----YGKDLVEKAKG-PELQAQAKAYFEKTQEQLTPLVKKAGTDLINFLNSFMDL----- -------------KTQPA--TQ >XP_043302053.1 apolipoprotein A-II [Cervus canadensis] -------------------------------------MKLLALTVLLLTVCSLE------ ---G--ALVRRQAEEP--DLQTLV----SQYFQTVAN----------------------- ----YGKDLVEKAKG-SELQTQAKAYFEKTQEELTPLFKKAGTDLLNFLSSFIDP----- -------------KKEPA--AH >KAB0357780.1 hypothetical protein FD754_001936 [Muntiacus muntjak] -------------------------------------MKLLALTVLLLTVCSLEVCVCFC VCAG--ALVRRQAEEP--DLQTLV----SQYFQTVAN----------------------- ----YGKDLVEKAKG-SELQTQAKAYFEKTQEELTPLFKKAGTDLLNFLSSFIDP----- -------------KKEPA--AH >KAB0385150.1 hypothetical protein FD755_000106 [Muntiacus reevesi] -------------------------------------MKLLALTVLLLTVCSLEECVCFC VCAG--ALVRRQTEEP--DLQTLV----SQYFQTVAN----------------------- ----YGKDLVEKAKG-SELQTQAKAYFEKTQEELTPLFKKAGTDLLNFLSSFIDP----- -------------KKEPA--AH >OWK05347.1 APOA2 [Cervus elaphus hippelaphus] -------------------------------------MKLLALTVLLLTVCSLE------ ---G--ALVRRQAEEP--DLQTLV----SQYFQTVAN----------------------- ----YGKDLVEKAKG-SELQTQAK---QKTQEELTPLFKKAGTDLLNFLSSFIDP----- -------------KKEPA--AH >KAF4021120.1 hypothetical protein G4228_013757 [Cervus hanglu yarkandensis] -------------------------------------MKLLALTVLLLTVCSLE------ ---GGCALVRRQAEEP--DLQTLV----SQYFQTVAN----------------------- ----YGKDLVEKAKG-SELQTQAK---QKTQEELTPLFKKAGTDLLNFLSSFIDP----- -------------KKEPA--AH >KYO19498.1 apolipoprotein A-II [Alligator mississippiensis] MTLRS-------RSAEL------------------ARMKVLAMAMLLLCLSHLE------ ---G--AVVRREAEAPAPNLLELY----THYIQRLSDV---------------------- ----LTKELPEKMKA-EEIKTQAKVYLEQANEQFAPIAKQLHNNLVELFTQLVET----- -------------GKKAA--EQ >XP_025050470.1 apolipoprotein A-II-like [Alligator sinensis] -------------------------------------MKVLAMAMLLLCLSHLE------ ---G--AVVRREAEAPAPNLLELY----THYIQRLSDV---------------------- ----LTKELPEKMKA-EEIKTQAKVYLEQANEQFAPIAKQLHNNLVELFTQLVET----- -------------GKKAT--EQ >tr|B3DFP9|B3DFP9_DANRE Apolipoprotein A-II OS=Danio rerio OX=7955 GN=apoa2 PE=1 SV=1 ------------------------------------------MKLTFALILALQV----- ---S-VCVWAQEWPVPDKELVDKYDGLRTVFIKRLVNAWEKIKTA-------VEPALEGS PTAGSLKDVVEELKKSPRVESFIKIA-GGLASELEPVVDKARLNALGVYGHYFRPYVGAY LDSAINNVKPVLDTVLPQ--GN >NP_001292478.1 apolipoprotein A-II preproprotein [Mus musculus] -------------------------------------MKLLAMVALLVTICSLE------ ---G--ALVKRQADGP--DMQSLF----TQYFQSMTD----------------------- ----YGKDLMEKAKT-SEIQSQAKAYFEKTHEQLTPLVRSAGTSLVNFFSSLMNL----- -------------EEKPAPAAK >NP_037244.1 apolipoprotein A-II preproprotein [Rattus norvegicus] -------------------------------------MKLLAMVALLVTICSLE------ ---G--ALVRRQAAET--DVQTLF----SQYLQSLTD----------------------- ----YGKDLMEKAQP-SEIQNQAKAYFQNAQERLTPFVQRTGTNLMDFLSRLMSP----- -------------EEKPAPAAK >NP_001008976.1 apolipoprotein A-II precursor [Pan troglodytes] -------------------------------------MKLLAATVLLLTICSLE------ ---G--ALVRRQAKEP--CVDNLV----SQYFQTVTD----------------------- ----YGKDLMEKVKS-PELQAEAKSYFEKSKEQLTPLIKKAGTELVNFLSYFMEL----- -------------GTQPA--TQ >NP_001300728.1 apolipoprotein A-II precursor [Canis lupus familiaris] -------------------------------------MKLLAVTVLLLVICSLE------ ---G--AFVRRQAEEP--NLQSLV----SQYFQTVTD----------------------- ----YGKDLMEKAKG-PELQAQAKAYFEKTQEQLTPLVKKAGTDLLNFLSNFMDL----- -------------KTQPA--TQ >NP_001039381.1 apolipoprotein A-II precursor [Bos taurus] -------------------------------------MKLLALTVLLLTICGLE------ ---G--ALVRRQAEES--NLQSLV----SQYFQTVAD----------------------- ----YGKDLVEKAKG-SELQTQAKAYFEKTQEELTPFFKKAGTDLLNFLSSFIDP----- -------------KKQPA--TR >NP_001173223.1 apolipoprotein A-II precursor [Sus scrofa] -------------------------------------MKLLAIAVLLFTICSLE------ ---G--ALVRRQAEEP--CLQSLV----SQYLQTVTD----------------------- ----FGKDLIEKAKG-SELQTQAKTYFEKTQEQLTPLVKKAGTDIFNFLSSFIGL----- -------------KTQPT--AQ >NP_001158123.1 apolipoprotein A-II precursor [Pongo abelii] -------------------------------------MKLLAATVLLLTICSLE------ ---G--ALVRRQAKEP--CVESPV----SQYFQTVTD----------------------- ----YGKDLMEKVKS-PELQAQAKSYFEKSKEQLTPLIKKAGTELVNFLNYFLEL----- ---------------------- >XP_002715298.1 PREDICTED: apolipoprotein A-II [Oryctolagus cuniculus] -------------------------------------MKLLAMTVLLLTICSLE------ ---G--ALVRRQAEEQ--SLQSLV----SQYLQTVTN----------------------- ----YSKDLMEKAKA-PELQAQAKAYFEKTQEQLTPLVKKAGTDLFNFLSNFMDL----- -------------KTQPA--AP >XP_003811880.1 apolipoprotein A-II [Pan paniscus] -------------------------------------MKLLAATVLLLTICSLE------ ---G--ALVRRQAKEP--CVDNLV----SQYFQTVTD----------------------- ----YGKDLMEKVKS-PELQAEAKSYFEKSKEQLTPLIKKAGTELVNFLSYFMEL----- -------------GTQPA--TQ >XP_004002742.1 apolipoprotein A-II [Ovis aries] -------------------------------------MKLLALTVLLLTICGLE------ ---G--ALVRRQAEEP--NLQSLV----SQYFQTVAD----------------------- ----YGKDLVEKAKG-SELQTQAKAYFEKTQEELTPLFKKAGTDLLNFLSSFIDP----- -------------KKQPA--AR >XP_004027815.1 apolipoprotein A-II [Gorilla gorilla gorilla] -------------------------------------MKLLAATVLLLTICSLE------ ---G--ALVRRQAKEP--CVESLV----SQYFQTVTD----------------------- ----YGKDLMEKVKS-PELQAEAKSYFEKSKEQLTPLIKKAGTELVNFLSYFVEL----- -------------GTQPA--TQ >XP_005677218.2 PREDICTED: apolipoprotein A-II [Capra hircus] -------------------------------------MKLLALTVLLLTICGLE------ ---G--ALVRRQAEEP--NLQSLV----SQYFQTVAD----------------------- ----YGKDLMEKAKG-SELQTQAKAYFEKTQEELTPLFKKAGTDLLNFLSSFIDP----- -------------KKQPA--AR >XP_020762724.1 apolipoprotein A-II [Odocoileus virginianus texanus] -------------------------------------MKLLALTVLLLTICSLE------ ---G--ALVRRQAEEP--DLQSLV----SQYFQTVAN----------------------- ----YGKDLVEKAKG-SELQTQAKAYFEKTQEELTPLFKKAGTDLLNFLSSFIDP----- -------------KKEPA--TN >XP_020565949.1 uncharacterized protein LOC101163028 [Oryzias latipes] MLIGTVPCYITLSRCELWVTDNSLPEKTVTSWVWSSSTSVMNAKYILALVLALQV----- ---S-MSLC--EIPAPSPELQSKYDSMKSTFIKRLENAYKKLQDA-------VSTSEQGQ ----VTKELVDSVHNRPEFQAVVKVA-SGLGSEAAPIVDRARSSLLGLYEQYLRPHVGES LSSGIDHIKIYLDQVMPA---E >XP_030250520.1 uncharacterized protein LOC115567819 isoform X2 [Sparus aurata] ----------------------------------------MHAKYALALILALQV----- ---S-VSLC--EIPDPPQELVDKYNEYKGTFYKRLLNLLSQAQTASGPMVEQASQDGRGQ ----AVREYAETLQAKPEFQAFVKVA-TALGEEASPLVDKARLKLLGAYQAYLRPYVGEW LADTITEAKVYLDKVMPA---E >XP_015805618.1 PREDICTED: uncharacterized protein LOC107379396 [Nothobranchius furzeri] ----------------------------------------MNAKLILALALVLQA----- ---S-VSFC--EIPAPSQELVQKYESLRDTFYSRLRNAYSKLQTT-------VGENEQGQ ----NAQNFIESLKDKPELQAIVKVA-SGLGAEARPLVDRARTSLLGLYEAYLRPHVGTG LSDTIDRIKVYLDEVMPA---Q
BMGE Cleaned alignment of selected proteins >NP_001634.1 apolipoprotein A-II preproprotein [Homo sapiens] MKLLAATVLLLTICSLEALVRRQAKEPCVESLVSQYFQTVTDYGKDLMEKVKSPELQAEAKSYFEKSKEQLTPLIKKAGTELVNFLSYFVELGTQPAQ >XP_003999611.1 apolipoprotein A-II isoform X3 [Felis catus] MKLLAMAVLLLTVCSLEALVRRQAEELSLQRLVSQYFQTVTDYGKDLVEKAKGPELQAQAKAYFEKTQEQLTPLVKKAGTDLINFLNSFMDLKTQPAQ >XP_043302053.1 apolipoprotein A-II [Cervus canadensis] MKLLALTVLLLTVCSLEALVRRQAEEPDLQTLVSQYFQTVANYGKDLVEKAKGSELQTQAKAYFEKTQEELTPLFKKAGTDLLNFLSSFIDPKKEPAH >KAB0357780.1 hypothetical protein FD754_001936 [Muntiacus muntjak] MKLLALTVLLLTVCSLEALVRRQAEEPDLQTLVSQYFQTVANYGKDLVEKAKGSELQTQAKAYFEKTQEELTPLFKKAGTDLLNFLSSFIDPKKEPAH >KAB0385150.1 hypothetical protein FD755_000106 [Muntiacus reevesi] MKLLALTVLLLTVCSLEALVRRQTEEPDLQTLVSQYFQTVANYGKDLVEKAKGSELQTQAKAYFEKTQEELTPLFKKAGTDLLNFLSSFIDPKKEPAH >OWK05347.1 APOA2 [Cervus elaphus hippelaphus] MKLLALTVLLLTVCSLEALVRRQAEEPDLQTLVSQYFQTVANYGKDLVEKAKGSELQTQAK---QKTQEELTPLFKKAGTDLLNFLSSFIDPKKEPAH >KAF4021120.1 hypothetical protein G4228_013757 [Cervus hanglu yarkandensis] MKLLALTVLLLTVCSLEALVRRQAEEPDLQTLVSQYFQTVANYGKDLVEKAKGSELQTQAK---QKTQEELTPLFKKAGTDLLNFLSSFIDPKKEPAH >KYO19498.1 apolipoprotein A-II [Alligator mississippiensis] MKVLAMAMLLLCLSHLEAVVRREAEAPNLLELYTHYIQRLSDLTKELPEKMKAEEIKTQAKVYLEQANEQFAPIAKQLHNNLVELFTQLVETGKKAAQ >XP_025050470.1 apolipoprotein A-II-like [Alligator sinensis] MKVLAMAMLLLCLSHLEAVVRREAEAPNLLELYTHYIQRLSDLTKELPEKMKAEEIKTQAKVYLEQANEQFAPIAKQLHNNLVELFTQLVETGKKATQ >tr|B3DFP9|B3DFP9_DANRE Apolipoprotein A-II OS=Danio rerio OX=7955 GN=apoa2 PE=1 SV=1 -----MKLTFALILALQCVWAQEWPVPELVDKYTVFIKRLVNSLKDVVEELKKPRVESFIKIA-GGLASELEPVVDKARLNALGVYGHYFRPTVLPQN >NP_001292478.1 apolipoprotein A-II preproprotein [Mus musculus] MKLLAMVALLVTICSLEALVKRQADGPDMQSLFTQYFQSMTDYGKDLMEKAKTSEIQSQAKAYFEKTHEQLTPLVRSAGTSLVNFFSSLMNLEEKPAK >NP_037244.1 apolipoprotein A-II preproprotein [Rattus norvegicus] MKLLAMVALLVTICSLEALVRRQAAETDVQTLFSQYLQSLTDYGKDLMEKAQPSEIQNQAKAYFQNAQERLTPFVQRTGTNLMDFLSRLMSPEEKPAK >NP_001008976.1 apolipoprotein A-II precursor [Pan troglodytes] MKLLAATVLLLTICSLEALVRRQAKEPCVDNLVSQYFQTVTDYGKDLMEKVKSPELQAEAKSYFEKSKEQLTPLIKKAGTELVNFLSYFMELGTQPAQ >NP_001300728.1 apolipoprotein A-II precursor [Canis lupus familiaris] MKLLAVTVLLLVICSLEAFVRRQAEEPNLQSLVSQYFQTVTDYGKDLMEKAKGPELQAQAKAYFEKTQEQLTPLVKKAGTDLLNFLSNFMDLKTQPAQ >NP_001039381.1 apolipoprotein A-II precursor [Bos taurus] MKLLALTVLLLTICGLEALVRRQAEESNLQSLVSQYFQTVADYGKDLVEKAKGSELQTQAKAYFEKTQEELTPFFKKAGTDLLNFLSSFIDPKKQPAR >NP_001173223.1 apolipoprotein A-II precursor [Sus scrofa] MKLLAIAVLLFTICSLEALVRRQAEEPCLQSLVSQYLQTVTDFGKDLIEKAKGSELQTQAKTYFEKTQEQLTPLVKKAGTDIFNFLSSFIGLKTQPTQ >NP_001158123.1 apolipoprotein A-II precursor [Pongo abelii] MKLLAATVLLLTICSLEALVRRQAKEPCVESPVSQYFQTVTDYGKDLMEKVKSPELQAQAKSYFEKSKEQLTPLIKKAGTELVNFLNYFLEL------ >XP_002715298.1 PREDICTED: apolipoprotein A-II [Oryctolagus cuniculus] MKLLAMTVLLLTICSLEALVRRQAEEQSLQSLVSQYLQTVTNYSKDLMEKAKAPELQAQAKAYFEKTQEQLTPLVKKAGTDLFNFLSNFMDLKTQPAP >XP_003811880.1 apolipoprotein A-II [Pan paniscus] MKLLAATVLLLTICSLEALVRRQAKEPCVDNLVSQYFQTVTDYGKDLMEKVKSPELQAEAKSYFEKSKEQLTPLIKKAGTELVNFLSYFMELGTQPAQ >XP_004002742.1 apolipoprotein A-II [Ovis aries] MKLLALTVLLLTICGLEALVRRQAEEPNLQSLVSQYFQTVADYGKDLVEKAKGSELQTQAKAYFEKTQEELTPLFKKAGTDLLNFLSSFIDPKKQPAR >XP_004027815.1 apolipoprotein A-II [Gorilla gorilla gorilla] MKLLAATVLLLTICSLEALVRRQAKEPCVESLVSQYFQTVTDYGKDLMEKVKSPELQAEAKSYFEKSKEQLTPLIKKAGTELVNFLSYFVELGTQPAQ >XP_005677218.2 PREDICTED: apolipoprotein A-II [Capra hircus] MKLLALTVLLLTICGLEALVRRQAEEPNLQSLVSQYFQTVADYGKDLMEKAKGSELQTQAKAYFEKTQEELTPLFKKAGTDLLNFLSSFIDPKKQPAR >XP_020762724.1 apolipoprotein A-II [Odocoileus virginianus texanus] MKLLALTVLLLTICSLEALVRRQAEEPDLQSLVSQYFQTVANYGKDLVEKAKGSELQTQAKAYFEKTQEELTPLFKKAGTDLLNFLSSFIDPKKEPAN >XP_020565949.1 uncharacterized protein LOC101163028 [Oryzias latipes] TSVMNAKYILALVLALQSLC--EIPAPELQSKYSTFIKRLENVTKELVDSVHNPEFQAVVKVA-SGLGSEAAPIVDRARSSLLGLYEQYLRPQVMPAE >XP_030250520.1 uncharacterized protein LOC115567819 isoform X2 [Sparus aurata] ---MHAKYALALILALQSLC--EIPDPELVDKYGTFYKRLLNAVREYAETLQAPEFQAFVKVA-TALGEEASPLVDKARLKLLGAYQAYLRPKVMPAE >XP_015805618.1 PREDICTED: uncharacterized protein LOC107379396 [Nothobranchius furzeri] ---MNAKLILALALVLQSFC--EIPAPELVQKYDTFYSRLRNNAQNFIESLKDPELQAIVKVA-SGLGAEARPLVDRARTSLLGLYEAYLRPEVMPAQ
PhyML tree of selected proteins (XP_020565949_1_uncharacterized_protein_LOC101163028__Oryzias_latipes_:0.09548592,(XP_015805618_1_PREDICTED__uncharacterized_protein_LOC107379396__Nothobranchius_furzeri_:0.27373058,(XP_030250520_1_uncharacterized_protein_LOC115567819_isoform_X2__Sparus_aurata_:0.24266717,tr_B3DFP9_B3DFP9_DANRE_Apolipoprotein_A_II_OS_Danio_rerio_OX_7955_GN_apoa2_PE_1_SV_1:0.79953099):0.14116115):0.08995621,(((NP_001292478_1_apolipoprotein_A_II_preproprotein__Mus_musculus_:0.12310691,NP_037244_1_apolipoprotein_A_II_preproprotein__Rattus_norvegicus_:0.24133892):0.11463368,((NP_001173223_1_apolipoprotein_A_II_precursor__Sus_scrofa_:0.1384176,(XP_003999611_1_apolipoprotein_A_II_isoform_X3__Felis_catus_:0.07517948,((NP_001300728_1_apolipoprotein_A_II_precursor__Canis_lupus_familiaris_:0.04199964,XP_002715298_1_PREDICTED__apolipoprotein_A_II__Oryctolagus_cuniculus_:0.07545363):0.00000001,(NP_001158123_1_apolipoprotein_A_II_precursor__Pongo_abelii_:0.0337498,((NP_001634_1_apolipoprotein_A_II_preproprotein__Homo_sapiens_:0.00000001,XP_004027815_1_apolipoprotein_A_II__Gorilla_gorilla_gorilla_:0.00000001):0.01029361,(NP_001008976_1_apolipoprotein_A_II_precursor__Pan_troglodytes_:0.00000001,XP_003811880_1_apolipoprotein_A_II__Pan_paniscus_:0.00000001):0.02091694):0.01029285):0.18379937):0.01136263):0.02504865):0.02694136,(XP_005677218_2_PREDICTED__apolipoprotein_A_II__Capra_hircus_:0.00000001,((XP_020762724_1_apolipoprotein_A_II__Odocoileus_virginianus_texanus_:0.00166474,((XP_043302053_1_apolipoprotein_A_II__Cervus_canadensis_:0.00000001,KAB0357780_1_hypothetical_protein_FD754_001936__Muntiacus_muntjak_:0.00000001):0.00000001,(KAB0385150_1_hypothetical_protein_FD755_000106__Muntiacus_reevesi_:0.01053064,(OWK05347_1_APOA2__Cervus_elaphus_hippelaphus_:0.00000001,KAF4021120_1_hypothetical_protein_G4228_013757__Cervus_hanglu_yarkandensis_:0.00000001):0.01071474):0.00000001):0.03012073):0.05398685,(XP_004002742_1_apolipoprotein_A_II__Ovis_aries_:0.00000001,NP_001039381_1_apolipoprotein_A_II_precursor__Bos_taurus_:0.02106007):0.00000001):0.01067174):0.08158587):0.12335642):0.33863168,(XP_025050470_1_apolipoprotein_A_II_like__Alligator_sinensis_:0.00999998,KYO19498_1_apolipoprotein_A_II__Alligator_mississippiensis_:0.00000001):0.54585765):1.71372752);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)