PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0045 | O00391 | Sulfhydryl oxidase 1 | QSOX1 | Q6, QSCN6, quiescin sulfhydryl oxidase 1 | Homo_sapiens | In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration (PubMed:23704371, PubMed:30367560, PubMed:23867277). |
Domains | Gene Ontology |
PF00085 (Thioredoxin) PF04777 (Evr1_Alr) PF18108 (QSOX_Trx1) PF18371 (FAD_SOX) |
GO:0003756 (enables) protein disulfide isomerase activity
GO:0016491 (enables) oxidoreductase activity GO:0016971 (enables) flavin-linked sulfhydryl oxidase activity GO:0016972 (enables) thiol oxidase activity GO:0071949 (enables) FAD binding GO:0006457 (involved in) protein folding GO:0016242 (involved in) negative regulation of macroautophagy GO:0085029 (involved in) extracellular matrix assembly GO:0005615 (is active in) extracellular space GO:0030173 (is active in) integral component of Golgi membrane GO:0000139 (located in) Golgi membrane GO:0005576 (located in) extracellular region GO:0005788 (located in) endoplasmic reticulum lumen GO:0005794 (located in) Golgi apparatus GO:0016020 (located in) membrane GO:0016021 (located in) integral component of membrane GO:0031093 (located in) platelet alpha granule lumen GO:0035580 (located in) specific granule lumen GO:0043231 (located in) intracellular membrane-bounded organelle GO:0045171 (located in) intercellular bridge GO:0070062 (located in) extracellular exosome GO:1904724 (located in) tertiary granule lumen |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |