PB0030

DATABASE

Click here to access PB0030 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0030	P01024	Complement C3	C3	AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p	Homo_sapiens	It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Domains

Gene Ontology

PF00207 (A2M) PF01759 (NTR) PF01821 (ANATO) PF01835 (MG2) PF07677 (A2M_recep) PF07678 (TED_complement) PF07703 (A2M_BRD) PF17789 (MG4) PF17790 (MG1) PF17791 (MG3)

GO:0004866 (enables) endopeptidase inhibitor activity GO:0005102 (enables) signaling receptor binding GO:0005515 (enables) protein binding GO:0031715 (enables) C5L2 anaphylatoxin chemotactic receptor binding GO:0001798 (involved in) positive regulation of type IIa hypersensitivity GO:0001934 (involved in) positive regulation of protein phosphorylation GO:0001970 (involved in) positive regulation of activation of membrane attack complex GO:0002376 (involved in) immune system process GO:0006629 (involved in) lipid metabolic process GO:0006631 (involved in) fatty acid metabolic process GO:0006954 (involved in) inflammatory response GO:0006955 (involved in) immune response GO:0006956 (involved in) complement activation GO:0006957 (involved in) complement activation, alternative pathway GO:0006958 (involved in) complement activation, classical pathway GO:0007165 (involved in) signal transduction GO:0007186 (involved in) G protein-coupled receptor signaling pathway GO:0009617 (involved in) response to bacterium GO:0010575 (involved in) positive regulation of vascular endothelial growth factor production GO:0010828 (involved in) positive regulation of glucose transmembrane transport GO:0010866 (involved in) regulation of triglyceride biosynthetic process GO:0010884 (involved in) positive regulation of lipid storage GO:0010951 (involved in) negative regulation of endopeptidase activity GO:0016322 (involved in) neuron remodeling GO:0035846 (involved in) oviduct epithelium development GO:0045087 (involved in) innate immune response GO:0045745 (involved in) positive regulation of G protein-coupled receptor signaling pathway GO:0045766 (involved in) positive regulation of angiogenesis GO:0048260 (involved in) positive regulation of receptor-mediated endocytosis GO:0050766 (involved in) positive regulation of phagocytosis GO:0060100 (involved in) positive regulation of phagocytosis, engulfment GO:0097242 (involved in) amyloid-beta clearance GO:0097278 (involved in) complement-dependent cytotoxicity GO:0150062 (involved in) complement-mediated synapse pruning GO:0150064 (involved in) vertebrate eye-specific patterning GO:1905114 (involved in) cell surface receptor signaling pathway involved in cell-cell signaling GO:2000427 (involved in) positive regulation of apoptotic cell clearance GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005788 (located in) endoplasmic reticulum lumen GO:0005886 (located in) plasma membrane GO:0009986 (located in) cell surface GO:0034774 (located in) secretory granule lumen GO:0035578 (located in) azurophil granule lumen GO:0070062 (located in) extracellular exosome GO:0072562 (located in) blood microparticle GO:0032991 (part of) protein-containing complex

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P01024|CO3_HUMAN Complement C3 OS=Homo sapiens OX=9606 GN=C3 PE=1 SV=2 MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVH DFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKV VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE KFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEV VLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKT PKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPL SITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMD RAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGA SGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDK GVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAEL QCPQPAARRRRSVQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEAC KKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVSRSEFPESWLWNVEDLKE PPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVV RNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVI VPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKE DIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTP TVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPSTWLTA YVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKD MALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMG RLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQR YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLR SEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDA KNTMILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSD RNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDG KLNKLCRDELCRCAEENCFIQKSDDKVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDE YIMAIEQTIKSGSDEVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSY IIGKDTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGCPN >tr|A5PMP6|A5PMP6_DANRE Complement component c3b, tandem duplicate 1 OS=Danio rerio OX=7955 GN=c3b.1 PE=4 SV=1 MLLQLLLWATLLCQICDGKAFPQRHKRTVWRHMRQIEPVKDPSPSFSLLAPAKIRPGTKQ NILVEGHNLAQVVEVTVVVYDYPNSQTALSRGSVFLNSDNNYSVLQTLEINPNLLLPDGK KKYVKLVAQFSNIYRAEKVMAVSFRSGHIFIQTDKPIYNPGDKVRFRAFVSDLEFRSSER TISLEIQNPDGIAVHGIGRVKAIDGVFSDIFSLSTVVKYALRIVQLCLLPAFNVTLTPKT SHLSLDAEKLEVEITARYLYGAQVKGVAYVLFGIEINGEKKRLTSMKQIDDVLNGGSVSL TMEEIKRAYPDINSLLGSTLYVKASVLTSSGSDLVEAEKSGIKIVKSPYMLTIKDTPKYY KPGLPLAMTVIVSNHDGSPTPNIPVKVTFLESPISVHSGTINIHINMPKTHILYGNSQIL KVETVDPSLKPEQQAIQEVYVKPYSTFSGHDNFLHVSVGASRVVVGGSVSVQMYIKSSLP NHRALVEHLTYIVLNKGKIIQAGRVNVKGQDVTSVHLLITTEMLPAFRFVAYYVLPWQHR AEVVADSVFVDVEDRCVGSLNVGPVDGEIVSSYSPGSSFKFQVKGDVGAKVSLVAVDNAI FLLSKNRLTQKKVWEVVDQADMGCTAGGGKDNMGVFSDAGLMFHSSTGGSTDSKEDCSSK TKRRRRSAAKLQLRDQLEKAYSDELLQRCCVDGMKEIPMPYSCYRRSLYITEDWSFFFVR DRVLQSMPKLHAEANVVGVRQDSYREVVVEEEEEAASVFEEDDLSDLEDIYVRSKFFESW LWTDIRLPSTAKSDGLAVFPVDTVLPDSITQWGFLAVSASPEKGVCVAEPYNVRVWKPFF IDLRLPHSVSRNEQVEIKAVIHNYKNSTLEVRSTPSVVMVILEKTEDMCSVAYTGQHRQQ VTVAAGSSKLITYTIIPLKTGELPLQVTAVAASFMGQDAVKKNLRVVVEGIQTLKVRSFV LNPSEKGGSAGQQLIQVKKMQLDAVVPKSVPETFVNVRGDLLADSIDNSIKEDSLAALIR MPGGCVEQNLARITLPLIAAHYLDRSADWEIVGISRREEAIKYIQRGYENQLNYKKSDDS YPPYANEGTSTWITAYVVKVFSMAHSFINVNEKHLCGPLLYLLKNKQGYDGTFQEDNPVY DTSMTGAMRGSEYKASLTAFVLIALAEAQDKVTCQDQEVNIRDKSRQAAGYLTEHFSRLT RPYTAAIACYALAVSNNACVKSMLLKFASPDHSHWPDSNNYFFTLEATGYALLALIKSGH MEEAEAPFRWLNEHRGIGGGYGSTQSTMVVLQALSEYLVKRPPPSDLNLLVQLSVPGRSD VRWTFNPNLAYVARSSRVPLDQEFSVAASGNGKGVLEVVTVYHQLPDVYENSTCNGFQLD VSIAETNEKTSSDVEKSFRLNVNVRALEERQVRMVILDIGLPTGFEPENSDLELLTNSVD RYINNFQVVDNLSDRGSLIIHLFKVSNKEAEMISFRLNQKFKVGLLQPSTVKVYQYYNKD KSCSRFYSPPEDKQQLDQICEGDVCRCSQGDCCVMKEDFAFFGKEQRNAAVCNGLHHAYR VKLISISQSHYYQYEMEIVQVIKEGTEEGLNEKERRMFLSHASCRTRLNLKEGQEYLVIG PITDVWNAGSTVSNKYVYTLGKETWVERWPDESECGSTLQKKCDELKSFAKKLIEDGCQA >tr|B8JKW4|B8JKW4_DANRE Complement component c3a, duplicate 1 OS=Danio rerio OX=7955 GN=c3a.1 PE=1 SV=1 MVKLLFLSAVLLSSALLTLCDPLYVLSAPNLLRVGSSENVFVEAQDYSKNAFEVKITVKN HPKKDKQILTKSVNLNAQNNFQILTDIKIPDDQNLFSDDPLEKQYVYLQAIFPDHTLEKV VLLSFQSGYIFVQTDKPIYTPSSTVQYRTLSLTPNLKPLSQTGITVEIMNPQNITVSSDK VYPVKGMKSGKYAIPEVASLGIWKVVTRFANTPQKTFTAEFEVKEYVLPTFEVKLQPSKL FYYVGDESLTVDIEAKYLFGKQVEGNAFVMFGVMDGETKTGITGSLQKIQILKGVGTAEL TKQMIETYKSIDKLVGQSIYVSVSLLTESGSEMVEAERRGIRIVTSPYTINFKKTAQFFK PGMPFDVSIYVTNPDETPAQNVIVEVNPGGVRGQTKANGIAKVTVNTQGNVLTQEITAQT KDPDITDEEQAVKKMTAHAYVPKGGSKNYLHIGIDAAELEIGDQMKVNLNTGQSPGVKDQ DYTFMILSKGQIVKIDRFKRQGQALITLSQPVTKEMVPSFRFVAYYHVGANEVVSDSVWV DVKDTCMGKLKLQVKNKQNNYNTGEEVKLQISGDPGARVGLVVVDKAVHVLNKNRLTQTK IWDVIEKHDTGCTAGGGRDVMGVFSDAGLMFESNTAGGTDTRLNPECPDPPKRRRRRRES ENLRTITATLAGQYADGQRQCCIDGMKDNKLGYTCERRATYIGDGPECVKAFLHCCDEMK KRKNIKTEEEEMILARSDDDDDYYTDSEEIVSRTQFPESWLWEEIDLCDNCPASAMEKAM YLKDSITTWQVLAVSMSPTLGICVAEPEEIVVFKSLFIDLKMPYSAVRGEQLEIKAIIHN YTPDKRKVRVEFMESADVCSLASKKGKYRTTVTIPKESSLSVPYVIIPMTLGNHMIEVKA AAYDAVYTDGVRKGLKVVSEGVLFPLQRPNVELNPVKNGDSPIIVRADIPADRVPGTPAH THISITGEEISQTVEQAISGSFMGQLIVQPHGCGEQNMIFMTLPVIATHYLDSTNQWEAI GMKRRDEAIGHIKTGYNRQQAYRKPDGSYAAWIDRPSSTWLTAYVAKIFAMANDLITIEE QVLCSALKWLVLNRQLPDGSFEEKAAVVHGEMVGDVQGRDAEASLTAFVTIAMQEGRELC GAIVGSLPESIRKAVSFLEGKLNKLTNPYAVALTSYAMAGADKLNKAVLMKFSTKGEAGT YWNVPGQQYHTREATSYAVLALVKARDFNAAGEAVHWLGSQHYSYGGSGTTQATIMVFQA VAEYRTQVKDSQNFNLEVELAVEGRSKPSRYTIKRDNRHVSRSDKVDINKDFNVTAKGTG KATLSVLTLYYARPVEKKSDCTLFDLSVKIDKDPETKHADAIETFKLTMDFFYKNPKSPA TMTILDIGIPTGFTVEYNDLEELTRGKEKYLEKFEMDKALSDRGSLILYLKMVSNKESER IAFRMHKMLNVGLLQPAAVTIYEYYSPNARCTKYFHPEREGVIYRLCKGDMCQCAEENCS LQKKGGFKDEERNIKACESGMDYVYKVKVKDMELAADADIYQMEVEQVLKEGTDQVIEGQ VKSFLGRPSCKESLGFVQGKSYLIMGKSTDLPKLGGSLQYILGEQTWIEYWPTSQESKSA EHRDRYIGITELENMLTKEGCAT >tr|F1QX13|F1QX13_DANRE Complement component c3a, duplicate 3 OS=Danio rerio OX=7955 GN=c3a.3 PE=1 SV=1 MEVKLLFLSAVLLSSALLTLCDPLYVLSAPNLLRVGSSENVFVEAQDYSGGPLNVRISVK NFPAKNVEMMQKTVTLTGAKYQSLTDIQIPGDRNYFSDDEKKQYVYLQAHFPSVTLEKVV MVSFQSGYLFVQTDKPIYTPGSNVHYRIFSMTPNLKPFSKPGITVDITNPQGITVASDTI FAEKGVKSSIYNIPEVTSLGMWKVVTRYANTPQKTFTAEFEVKEYVLPTFEVKLKTSKSF YYVGDSKPKNNEDDSLTVDMEAKYLFGKKMDGNAFVVFGVMDGAMKTSIVNSLQKVQVFN GVGTAELTREMITKTFKNIKDLVGKSIYVSVNLLTESGSEMVEAEKRGIQIVTSPYTIHY KRTSQFFKPGMPLGVSVYVTNPDETPAEDVEVEVLVDGVGGVNSKTKANGIAKVTVNTKA GVSTLKITATTRDPELANEQQADKTMIAQAYKTNLGSKNYLHINIESAEFEIGDQMTVYL NTGESPGVKDQDFTYMILSKGQIVLAERFKRQGQTLVSLSLPVTKDMVPSFRFVAYYHVG KDEVVSDSVWVDVKDTCMGKLKVEVTEKQKFYETGNEVNLQISGDFGARVGLVVVDKAVQ VLNKNRLTQSKIWDVIEKHDTGCTGGGGKDSMGVFSDAGLMFESDPAGGTNTRTEPKCPA PPKRKRRSESLQTITTTLAGQYTEKIRPCCYDGMRNNRIGYTCERRASYVIDGEECVKAF LHCCKEVKNHKETEEEELILARKDDEETYEEDYEDYDDITSRKQFPESWLWEEFDLCDKC SKPSKNKVTYLKDSITTWQILAISLSPTHGICVAEPEEIVVFKSFFIDLKVPYSAVRGEQ VEIKAIIHNYTPKHLKKVRVEFLETAGVCSAASKKGKYRATVNVDKDSSIAVSFVIVPMT LESQHIEVKASILDYTDGVRKTLKVVSEGVLTKFQSQKLELNPAKKGEQPLLLRAGIPGD QVPGTPVHSYITVTGEEISQSIEHAINGSFMGELIKRPGGCGEQNMAKMTLPVVATHYLD NTNQWESVGIDRRKVAINHIKTGYDGQLKYRKPDGSYAIWINTPSSTWLTAYVAKVFAMA NDFFAIEENVICSALKWLVMHKQLPDGSFKEDAPVYDKSIMGGIEGQNTDVSLTAFVLIA MQEGKEICGGTVGSLHESMRKAVAFLKDQLPKLTNPYAVALTSYALANADSLNKAILMMH STKVNDERFWNVPERQYYSIEATAYAVLALVKAKDYDTAGEAVHWLAKQKSSHGGYDTTQ VTIMVFQAVAEYHAQTQDLNNFDLNVELVVPGRRKTDRWTIQRSNVHLARSGNVDLNKDF TVIAKGTGSAILSVLTLYYARPFEKKTDCTFFDLSVKLDKIPETKPGTNGTYNFILDFFY KNKKNDATMTILDIGLPTGFDIDEADLKQLSTGKERYIQKYEKNKVLSERGSLIIYLNKV SHEVSEKLVFRMHKTFNVALLQPASVTIYEYYSPDARCKKYYHPEREDSALYRLCKGDLC VCAEENCSYQKKNHVDESKRLIKACEPHLDYIYKAKLVKMDLKQDSDIYHMKVEKTVKEG TDTDVEGKVKQFLARPSCRVSLGLVEGKSYLIMGNSVDLPTLGGSLQYVIGEQTWIEYWP TSDESKSAEHRDRYIGMTAVENMFTTGGCLT
Selected proteins from model organisms >NP_000055.2 complement C3 preproprotein [Homo sapiens] MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLS SEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKVVLVSLQSGYLFIQTDKTIYT PGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVLPLSWDIPELVNMGQWKIRAYY ENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQ RISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVT SPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPL SITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMDRAHEAKIRYY TYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCV GSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPG SGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVQLTEKRMDKVGKYPKELRKCCEDGMRE NPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVSRSEFPES WLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVV RNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEV EVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRI LLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIK KGYTQQLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQE DAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVA IAGYALAQMGRLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQR YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGF TVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATM SILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVE LIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENCFIQKSDDKVTLEERLDKACEPG VDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGSDEVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSD FWGEKPNLSYIIGKDTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGCPN >tr|A5PMP6|A5PMP6_DANRE Complement component c3b, tandem duplicate 1 OS=Danio rerio OX=7955 GN=c3b.1 PE=4 SV=1 MLLQLLLWATLLCQICDGKAFPQRHKRTVWRHMRQIEPVKDPSPSFSLLAPAKIRPGTKQ NILVEGHNLAQVVEVTVVVYDYPNSQTALSRGSVFLNSDNNYSVLQTLEINPNLLLPDGK KKYVKLVAQFSNIYRAEKVMAVSFRSGHIFIQTDKPIYNPGDKVRFRAFVSDLEFRSSER TISLEIQNPDGIAVHGIGRVKAIDGVFSDIFSLSTVVKYALRIVQLCLLPAFNVTLTPKT SHLSLDAEKLEVEITARYLYGAQVKGVAYVLFGIEINGEKKRLTSMKQIDDVLNGGSVSL TMEEIKRAYPDINSLLGSTLYVKASVLTSSGSDLVEAEKSGIKIVKSPYMLTIKDTPKYY KPGLPLAMTVIVSNHDGSPTPNIPVKVTFLESPISVHSGTINIHINMPKTHILYGNSQIL KVETVDPSLKPEQQAIQEVYVKPYSTFSGHDNFLHVSVGASRVVVGGSVSVQMYIKSSLP NHRALVEHLTYIVLNKGKIIQAGRVNVKGQDVTSVHLLITTEMLPAFRFVAYYVLPWQHR AEVVADSVFVDVEDRCVGSLNVGPVDGEIVSSYSPGSSFKFQVKGDVGAKVSLVAVDNAI FLLSKNRLTQKKVWEVVDQADMGCTAGGGKDNMGVFSDAGLMFHSSTGGSTDSKEDCSSK TKRRRRSAAKLQLRDQLEKAYSDELLQRCCVDGMKEIPMPYSCYRRSLYITEDWSFFFVR DRVLQSMPKLHAEANVVGVRQDSYREVVVEEEEEAASVFEEDDLSDLEDIYVRSKFFESW LWTDIRLPSTAKSDGLAVFPVDTVLPDSITQWGFLAVSASPEKGVCVAEPYNVRVWKPFF IDLRLPHSVSRNEQVEIKAVIHNYKNSTLEVRSTPSVVMVILEKTEDMCSVAYTGQHRQQ VTVAAGSSKLITYTIIPLKTGELPLQVTAVAASFMGQDAVKKNLRVVVEGIQTLKVRSFV LNPSEKGGSAGQQLIQVKKMQLDAVVPKSVPETFVNVRGDLLADSIDNSIKEDSLAALIR MPGGCVEQNLARITLPLIAAHYLDRSADWEIVGISRREEAIKYIQRGYENQLNYKKSDDS YPPYANEGTSTWITAYVVKVFSMAHSFINVNEKHLCGPLLYLLKNKQGYDGTFQEDNPVY DTSMTGAMRGSEYKASLTAFVLIALAEAQDKVTCQDQEVNIRDKSRQAAGYLTEHFSRLT RPYTAAIACYALAVSNNACVKSMLLKFASPDHSHWPDSNNYFFTLEATGYALLALIKSGH MEEAEAPFRWLNEHRGIGGGYGSTQSTMVVLQALSEYLVKRPPPSDLNLLVQLSVPGRSD VRWTFNPNLAYVARSSRVPLDQEFSVAASGNGKGVLEVVTVYHQLPDVYENSTCNGFQLD VSIAETNEKTSSDVEKSFRLNVNVRALEERQVRMVILDIGLPTGFEPENSDLELLTNSVD RYINNFQVVDNLSDRGSLIIHLFKVSNKEAEMISFRLNQKFKVGLLQPSTVKVYQYYNKD KSCSRFYSPPEDKQQLDQICEGDVCRCSQGDCCVMKEDFAFFGKEQRNAAVCNGLHHAYR VKLISISQSHYYQYEMEIVQVIKEGTEEGLNEKERRMFLSHASCRTRLNLKEGQEYLVIG PITDVWNAGSTVSNKYVYTLGKETWVERWPDESECGSTLQKKCDELKSFAKKLIEDGCQA >tr|B8JKW4|B8JKW4_DANRE Complement component c3a, duplicate 1 OS=Danio rerio OX=7955 GN=c3a.1 PE=1 SV=1 MVKLLFLSAVLLSSALLTLCDPLYVLSAPNLLRVGSSENVFVEAQDYSKNAFEVKITVKN HPKKDKQILTKSVNLNAQNNFQILTDIKIPDDQNLFSDDPLEKQYVYLQAIFPDHTLEKV VLLSFQSGYIFVQTDKPIYTPSSTVQYRTLSLTPNLKPLSQTGITVEIMNPQNITVSSDK VYPVKGMKSGKYAIPEVASLGIWKVVTRFANTPQKTFTAEFEVKEYVLPTFEVKLQPSKL FYYVGDESLTVDIEAKYLFGKQVEGNAFVMFGVMDGETKTGITGSLQKIQILKGVGTAEL TKQMIETYKSIDKLVGQSIYVSVSLLTESGSEMVEAERRGIRIVTSPYTINFKKTAQFFK PGMPFDVSIYVTNPDETPAQNVIVEVNPGGVRGQTKANGIAKVTVNTQGNVLTQEITAQT KDPDITDEEQAVKKMTAHAYVPKGGSKNYLHIGIDAAELEIGDQMKVNLNTGQSPGVKDQ DYTFMILSKGQIVKIDRFKRQGQALITLSQPVTKEMVPSFRFVAYYHVGANEVVSDSVWV DVKDTCMGKLKLQVKNKQNNYNTGEEVKLQISGDPGARVGLVVVDKAVHVLNKNRLTQTK IWDVIEKHDTGCTAGGGRDVMGVFSDAGLMFESNTAGGTDTRLNPECPDPPKRRRRRRES ENLRTITATLAGQYADGQRQCCIDGMKDNKLGYTCERRATYIGDGPECVKAFLHCCDEMK KRKNIKTEEEEMILARSDDDDDYYTDSEEIVSRTQFPESWLWEEIDLCDNCPASAMEKAM YLKDSITTWQVLAVSMSPTLGICVAEPEEIVVFKSLFIDLKMPYSAVRGEQLEIKAIIHN YTPDKRKVRVEFMESADVCSLASKKGKYRTTVTIPKESSLSVPYVIIPMTLGNHMIEVKA AAYDAVYTDGVRKGLKVVSEGVLFPLQRPNVELNPVKNGDSPIIVRADIPADRVPGTPAH THISITGEEISQTVEQAISGSFMGQLIVQPHGCGEQNMIFMTLPVIATHYLDSTNQWEAI GMKRRDEAIGHIKTGYNRQQAYRKPDGSYAAWIDRPSSTWLTAYVAKIFAMANDLITIEE QVLCSALKWLVLNRQLPDGSFEEKAAVVHGEMVGDVQGRDAEASLTAFVTIAMQEGRELC GAIVGSLPESIRKAVSFLEGKLNKLTNPYAVALTSYAMAGADKLNKAVLMKFSTKGEAGT YWNVPGQQYHTREATSYAVLALVKARDFNAAGEAVHWLGSQHYSYGGSGTTQATIMVFQA VAEYRTQVKDSQNFNLEVELAVEGRSKPSRYTIKRDNRHVSRSDKVDINKDFNVTAKGTG KATLSVLTLYYARPVEKKSDCTLFDLSVKIDKDPETKHADAIETFKLTMDFFYKNPKSPA TMTILDIGIPTGFTVEYNDLEELTRGKEKYLEKFEMDKALSDRGSLILYLKMVSNKESER IAFRMHKMLNVGLLQPAAVTIYEYYSPNARCTKYFHPEREGVIYRLCKGDMCQCAEENCS LQKKGGFKDEERNIKACESGMDYVYKVKVKDMELAADADIYQMEVEQVLKEGTDQVIEGQ VKSFLGRPSCKESLGFVQGKSYLIMGKSTDLPKLGGSLQYILGEQTWIEYWPTSQESKSA EHRDRYIGITELENMLTKEGCAT >tr|F1QX13|F1QX13_DANRE Complement component c3a, duplicate 3 OS=Danio rerio OX=7955 GN=c3a.3 PE=1 SV=1 MEVKLLFLSAVLLSSALLTLCDPLYVLSAPNLLRVGSSENVFVEAQDYSGGPLNVRISVK NFPAKNVEMMQKTVTLTGAKYQSLTDIQIPGDRNYFSDDEKKQYVYLQAHFPSVTLEKVV MVSFQSGYLFVQTDKPIYTPGSNVHYRIFSMTPNLKPFSKPGITVDITNPQGITVASDTI FAEKGVKSSIYNIPEVTSLGMWKVVTRYANTPQKTFTAEFEVKEYVLPTFEVKLKTSKSF YYVGDSKPKNNEDDSLTVDMEAKYLFGKKMDGNAFVVFGVMDGAMKTSIVNSLQKVQVFN GVGTAELTREMITKTFKNIKDLVGKSIYVSVNLLTESGSEMVEAEKRGIQIVTSPYTIHY KRTSQFFKPGMPLGVSVYVTNPDETPAEDVEVEVLVDGVGGVNSKTKANGIAKVTVNTKA GVSTLKITATTRDPELANEQQADKTMIAQAYKTNLGSKNYLHINIESAEFEIGDQMTVYL NTGESPGVKDQDFTYMILSKGQIVLAERFKRQGQTLVSLSLPVTKDMVPSFRFVAYYHVG KDEVVSDSVWVDVKDTCMGKLKVEVTEKQKFYETGNEVNLQISGDFGARVGLVVVDKAVQ VLNKNRLTQSKIWDVIEKHDTGCTGGGGKDSMGVFSDAGLMFESDPAGGTNTRTEPKCPA PPKRKRRSESLQTITTTLAGQYTEKIRPCCYDGMRNNRIGYTCERRASYVIDGEECVKAF LHCCKEVKNHKETEEEELILARKDDEETYEEDYEDYDDITSRKQFPESWLWEEFDLCDKC SKPSKNKVTYLKDSITTWQILAISLSPTHGICVAEPEEIVVFKSFFIDLKVPYSAVRGEQ VEIKAIIHNYTPKHLKKVRVEFLETAGVCSAASKKGKYRATVNVDKDSSIAVSFVIVPMT LESQHIEVKASILDYTDGVRKTLKVVSEGVLTKFQSQKLELNPAKKGEQPLLLRAGIPGD QVPGTPVHSYITVTGEEISQSIEHAINGSFMGELIKRPGGCGEQNMAKMTLPVVATHYLD NTNQWESVGIDRRKVAINHIKTGYDGQLKYRKPDGSYAIWINTPSSTWLTAYVAKVFAMA NDFFAIEENVICSALKWLVMHKQLPDGSFKEDAPVYDKSIMGGIEGQNTDVSLTAFVLIA MQEGKEICGGTVGSLHESMRKAVAFLKDQLPKLTNPYAVALTSYALANADSLNKAILMMH STKVNDERFWNVPERQYYSIEATAYAVLALVKAKDYDTAGEAVHWLAKQKSSHGGYDTTQ VTIMVFQAVAEYHAQTQDLNNFDLNVELVVPGRRKTDRWTIQRSNVHLARSGNVDLNKDF TVIAKGTGSAILSVLTLYYARPFEKKTDCTFFDLSVKLDKIPETKPGTNGTYNFILDFFY KNKKNDATMTILDIGLPTGFDIDEADLKQLSTGKERYIQKYEKNKVLSERGSLIIYLNKV SHEVSEKLVFRMHKTFNVALLQPASVTIYEYYSPDARCKKYYHPEREDSALYRLCKGDLC VCAEENCSYQKKNHVDESKRLIKACEPHLDYIYKAKLVKMDLKQDSDIYHMKVEKTVKEG TDTDVEGKVKQFLARPSCRVSLGLVEGKSYLIMGNSVDLPTLGGSLQYVIGEQTWIEYWP TSDESKSAEHRDRYIGMTAVENMFTTGGCLT >XP_024207219.1 complement C3 [Pan troglodytes] MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETVVLEAHDAQGDVPVTVIVHDFPGKKLVLSSEKTVLTPAT NHMGNVTFMIPANREFKSEKGRNKFVTVQATFGAQVVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVG RTVMVNIENPEGIPVKQDSLSSQNQFGILPLSWDIPELVNMGQWKIQAYYENSPQEVFSAEFEVKEYVLPSFEVIVEPTE KFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGLGEVVLSRKVLLEGVQNPRAEDLV GKSLYVSVTVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSL TQGDGVAKLSINTHPSQKPLSITVRTKKQELSEAEQATSTMQALPYSTVGNSNNYLHLSVPRTELRPGETLNVNFLLRMD RAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCV GSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFS DAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVLLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEAC KKVFLDCCNYITELRRQHARAGHLGLARSDLDEDIIAEENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSIT TWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKR RHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKE DIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLE KRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQE DAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMG RLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALA QYQKDVPDHKELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNK FDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLASGVDRYISKYELDKAFSD RNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLAESCTRFYHPEKEDGKLNKLCRDELCRCAEENCFI QKSDDKVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGSDEVQVGQQRTFISPIKCREALKLEEKK HYLMWGLSSDFWGEKPNLSYIIGKDTWVEHWPEEDECQDEENQQQCQDLGAFTESMVVFGCPN >XP_043322320.1 complement C3 [Cervus canadensis] MQPTSGPSLLLLLLLASLPMALGSPMYSMITPNILRLESEETVVLEAHGGQGNIPVSVTVHDFPAKKQVLSNENTQLNND NGYLATVTIKIPASKELKSDKGHKFVTVLATFGDVAVEKVVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDHKLLPVG QTVIVSIETPDGIPVKRDSQSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQVFSADFEVKEYVLPSFEVQLEPEE KFYYIDDPDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILRRQVLLNGVQPSRADALV GKSIYVSATVILQSGSDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTQGSNVQSLT QDDGVAKLSINTQNKRDPLTITVRTKKDNIPEERQATKTMQALPYNTQGNSNNYLHLSVPRMELKPGETLNVNFHLRTDP GQQAKIRYYTYMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLINANGQREVVADSVWVDVKDSCMG TLVVKSGGKEEKHHRPGQQITLKIEADQGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTD AGLALKTSQGLETKQRADPLCPQPAVRRRRSVQLMEKRMDKVGQYSGDLRKCCEDGMRDNPMKFPCQRRAQFILQGDACV KAFLDCCGYITQLRQQHSRDSTLELARSDLDDEIIPEEDIISRSQFPESWLWTIIEDFKQADKNGISTKLTNVFLKDSIT TWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYREAENLKVRVELLYNPAFCSLATAKK RHQQTLVIPARSSLAVPYVIVPLKVGLHEVEVKAAVYNHFISDGVKKTLKVVPEGIRVNKTVAIRTLNPEHLGQGGVQRV EVPAADLSDQVPDTESETKILLQGTPVAQMTEDAVDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGVE KRQQALELIRKGYTQQLAFRQKNSAYAAFLGRPASTWLTAYVVKVFALSANLIAIDSKDLCETVKWLILEKQKPDGIFQE DGPVIHQEMIGGFRDTREKDVSLTAFVLIALHEAKDICEAQVNSLGRSINKAGDFLENHYRELRRPYTVAIAAYALALLG KLEDDRLTKFMNTAKEKNRWEEPNQKLYNVEATSYALLALLARKDYDTVHPVVRWLNEQRYYGGGYGSTQATFMVFQALA QYQKDVPDHKDLNLDVSIQLPSRNSLVKHRILWESASLLRSEETKENERFTVRAEGKGQGTLSVVTVYHAKLKGKVSCKK FDLQVSIRPAPEPVKKPQDAKGSMILDICTRYLGDQDATMSILDISMMTGFSPDIDDLKLLSSGVDRYISKYEMNKDSNK NTLIIYLDKVSHTVEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCRCAEENCFMH HLDEEITLDGRLDKACEPGVDYVYKTRLVQKKLEDDFDEYIMVIEQIIKSGSDEVQVNQQRKFISHIKCREALKLKEGAH YLVWGVSSDLWGEKPNISYIIGKDTWVELWPDAEECQDEENQKQCEDLANFTENMVVFGCPN >XP_027825575.2 complement C3 [Ovis aries] MQPTSGPSLLLLLLLASLPMALGNPMYSMITPNILRLESEETVVLEAHGGQGNIQVSVTVHDFPAKKQVLSNENTQLNSN NGYLSTVTIKIPASKELKSDKGHKFVIVVATFGNVQVEKVVLISLQSGYLFIQTDKTIYTPGSSVLYRVFTVDHKLLPVG QTVFISIETPDGVLVKRDSLSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQVFSTEFEVKEYVLPSFEVQLEPEE KFYYVDDPDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILKRQVLLNGVQPSRADALV GKSIYVSATVILQSGSDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTQGSNVQSLT QDDGVAKLSINTQNKRDPLTITVRTKKDNIPEGRQATRTMQALPYNTQGNSNNYLHLSVPRVELKPGETLNVNFHLRTDP DQQAKIRYYTYMIMNKGKLLKVGRQEREPGQDLVVLPLTITSDFIPSFRLVAYYTLSNANGQREVVADSVWVDVKDSCMG TLVVKNGGKEEKHHRPGQQITLKIEANQGSRVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTD AGLTFKTSQGLETQQRSDPQCPKPAARRRRSVQLMEKRMDKVGQYSGDLRKCCEDGMRDNPMKFPCQRRAQFILQGDACV KAFLDCCEYIARLRQQHSRDGALELARSDLEDEIIPEEDIISRSQFPESWLWTIIDDFKQADKNGISTKLMNVFLKDSIT TWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYREAENLKVRVELLYNPAFCSLATAKK RHQQTITIPARSSVAVPYVIVPLKVGLHEVEVKAAVYNHFISDGVKKTLKVVPEGIRVNKTVAIRTLNPEYLGQDGVQRE EVPAADLSDQVPDTESETKILLQGTPVAEMAEDAIDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGME KRQEALELIRKGYTQQLAFRQKSSAYAAFQNRPPSTWLTAYVVKVFALSTNLIAIDSRDLCETVKWLILEKQKPDGIFQE DGPVIHQEMIGGFKDTREKDVSLTAFVLIALHEAKDICEAQVNSLGPSITKAGDFLENHYRELRRPYTVAIAAYALALLG KLEDDRLTKFLNTAKEKNRWEEPNKKLYNVEATSYALLALLARKDFDTVPPVVRWLNEQRYYGGGYGSTQATFMVFQALA QYQKDVPDHKELNLDVSIHLPSRNSLVKHRILWESASLLRSEETKENERFTVRAEGKGQGTLSVVTVYHAKLKGKVSCKK FDLRVSIRPALEPVKKPQDAKGSMILDICTKYLGDQDATMSILDISMMTGFSPDIDDLKLLSTGVDRYISKYEMNRDSNK NTLIIYLDKISHTQEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCRCAEENCFMH HTEEVITLENRLDRACEPGVDYVYKTRLIQKKLEEDFDEYIMVIEQIIKSGSDEVQVKQERKFISHIKCREALKLKEGAH YLVWGVSSDLWGDKPNISYIIGKDTWVELWPEAEECQDEENQKQCEDLASFTENMVVFGCPN >KAB0363358.1 hypothetical protein FD754_007514 [Muntiacus muntjak] MQPTSGPSLLLLLLLASLPMALGSPMYSMITPNILRLESEETVVLEAHGGQGNIPVSVTVHDFPAKKQVLSNENTQLNND NGYLATVTIKIPASKELKSDKGHKFVTVLATFGGVPVEKVVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDHKLLPVG QTVIVSIETPDGIPVKRDSQSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQVFSADFEVKEYVLPSFEVQLEPEE KFYYIDDPDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILRRQVLLNGVQPSRADALV GKSIYVSATVILQSGRRPRMKEGSSLTGKNHDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPAR HIPVVTQGSNVQSLTQDDGVAKLSINTQNKRDPLTITVRTKKDNIPEERQATKTMQALPYNTQGNSNNYLHLSVPRVELK PGETLNVNFHLRTDPGQQAKIRYYTYMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLINANGQREV VADSVWVDVKDSCMGTLVVKSGGKEEKHHRPGQQITLKIEADQGARVGLVAVDKGVFVLNKKNKLTQRKIWDVVEKADIG CTPGSGRDYAGVFTDAGLALKTSQGLETKQRADPLCPQPAVRRRRSVQLMEKRMDKVGQYSGDLRKCCEDGMRDNPMKFP CQRRAQFILQGDACVKAFLDCCEYIAQLRQQHSRHSALELARSDLDDEIIPEEDIISRSQFPESWLWTIIEDFKQADKNG ISMKLTNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYREAETLKVRVE LLYNPAFCSLATAKKRHQQTLVIPARSSLAVPYVIVPLKVGLHEVEVKAAVYNHFISDGVKKTLKVVPEGIRVNKTVAIR TLNPEHLGQDGVQRVEVPAADLSDQVPDTESETKILLQGTPVAQMTEDAVDGERLKHLIQTPSGCGEQNMIGMTPTVIAV HYLDSTEQWEKFGVEKRQQALDLIRKGYTQQLAFRQKNSAYAAFLGRPASTWLTAYVVKVFALSANLIAIDSKDLCETVK WLILEKQKPDGIFQEDGPVIHQEMIGGFRDAREKDVSLTAFVLIALHEAKDICEAQVNSLGRSINKAGDFLENHYRELRR PYTVAIAAYALALLGKLEDDRLTKFMNTAKEKNRWEEPNQKLYNVEATSYALLALLARKDYDTVPPVVRWLNEQRYYGGG YGSTQATFMVFQALAQYQKDIPDHKDLNLDVSIQLPSRNSLVKHRILWESASLLRSEETKENERFTVRAEGKGQGTLSVV TVYHAKLKGKVTCKKFDLQVSIHPAPETVKKPQDAKGSMILDICTRYLGDQDATMSILDISMMTGFSPDIDDLKLLSSGV DRYISKYEMNKDSNKNTLIIYLDKVSHTVEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLC HKDTCRCAEENCFMHHPEEEITLNGRLDKACEPGVDYVYKTRLIQKKLEDDFDEYMMVIEQIIKSGSDEVQVNQERKFIS HIKCREALKLKEGAHYLVWGVSSDLWGEKPNISYIIGKDTWVELWPDAEECQDEENQKQCEDLANFTENMVVFGCPN >KAB0388260.1 hypothetical protein FD755_003216 [Muntiacus reevesi] MQPTSGPSLLLLLLLASLPMALGSPMYSMITPNILRLESEETVVLEAHGGQGNIPVSVTVHDFPAKKQVLSNENTQLNND NGYLATVTIKIPASKELKSDKGHKFVTVLATFGGVPVEKVVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDHKLLPVG QTVIVSIETPDGIPVKRDSQSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQVFSADFEVKEYVLPSFEVQLEPEE KFYYIDDPDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILRRQVLLNGVQPSRADALV GKSIYVSATVILQSGRRPRMKEGSSLTGKNHDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPAR HIPVVTQGSNVQSLTQDDGVAKLSINTQNKRDPLTITVRTKKDNIPEERQATKTMQALPYNTQGNSNNYLHLSVPRVELK PGETLNVNFHLRTDPGQQAKIRYYTYMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLINANGQREV VADSVWVDVKDSCMGTLVVKSGGKEEKHHRPGQQITLKIEADQGARVGLVAVDKGVFVLNKKNKLTQRKIWDVVEKADIG CTPGSGRDYAGVFTDAGLALKTSQGLETKQRADPLCPQPAVRRRRSVQLMEKRMDKVGQYSGDLRKCCEDGMRDNPMKFP CQRRAQFILQGDACVKAFLDCCEYIAQLRQQHSRHSALELARSDLDDEIIPEEDIISRSQFPESWLWTIIEDFKQADKNG ISTKLTNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYREAETLKVRVE LLYNPAFCSLATAKKRHQQTLVIPARSSLAVPYVIVPLKVGLHEVEVKAAVYNHFISDGVKKTLKVVPEGIRVNKTVAIR TLNPEHLGQDGVQRVEVPAADLSDQVPDTESETKILLQGTPVAQMTEDAVDGERLKHLIQTPSGCGEQNMIGMTPTVIAV HYLDSTEQWEKFGVEKRQQALELIRKGYTQQLAFRQKNSAYAAFLGRPASTWLTAYVVKVFALSANLIAIDSKDLCETVK WLILEKQKPDGIFQEDGPVIHQEMIGGFRDAREKDVSLTAFVLIALHEAKDICEAQVNSLGRSINKAGDFLENHYRELRR PYTVAIAAYALALLGKLEDDRFTKFMNTAKEKNRWEEPNQKLYNVEATSYALLALLARKDYDTVPPVVRWLNEQRYYGGG YGSTQATFMVFQALAQYQKDIPDHKDLNLDVSIQLPSRNSLVKHRILWESASLLRSEETKENERFTVRAEGKGQGTLSVV TVYHAKLKGKVTCKKFDLQVSIHPAPETVKKPQDAKGSMILDICTRYLGDQDATMSILDISMMTGFSPDIDDLKLLSSGV DRYISKYEMNKDSNKNTLIIYLDKVSHTVEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLC HKDTCRCAEENCFMHHLEEEITLNGRLDKACEPGVDYVYKTRLIQKKLEDDFDEYMMVIEQIIKSGSDEVQVNQERKFIS HIKCREALKLKEGAHYLVWGVSSDLWGEKPNISYIIGKDTWVELWPDAEECQDEENQKQCEELANFTENMVVFGCPN >KAF4014700.1 hypothetical protein G4228_005895 [Cervus hanglu yarkandensis] MAVSERRGLGRGSPAEWRPWLLLLLLLGGSSGRIHRLTLTGEKRADIQLNSFGFYTNGSLEVDLSLLRLGCQNTEEKAPL VGFSLTRVRSGSIRSYSNRDSHECPLRKNSSSLLVLFLINTKDLQVQVRKYGEQKKLFISAGLLPESPSEPGLPKSEHMV TPKVDHAGTTAAPDKAKLKPTGSQGDRQGVSGKDQELVLGLGHLNNSYNFSFHVVIGSRAEEGQYNLNFHNCDNSVPGRE QPFDITVMIREKNPEGYLSAAEIPLFKLYMVMSACFLGAGIFWVSILCKNTYNVFKIHWLMAALTFTKSVSLLFHSINYY FINSQGHPIEGLAVMHYITHLLKGALLFITIALIGSGWAFVKYVLSDKEKKIFGIVIPLQVLANVAYIVIESREEGASDY GIWKEILFLVDLICCGTILFPVVWSIRHLQDASGTDGKVAVNLAKLKLFRHYYVMVICYIYFTRIIAILLRVVVPFQWQW LYQLLVEGSTLAFFVLTGYKFQPARDNPYLQLPQEDEEEMQMEQVYSMITPNILRLESEETVVLEAHGGQGNIPVSVTVH DFPAKKQVLSNENTQLNNDNGYLATVTIKIPASKELKSDKGHKFVTVLATFGDVAVEKVVLISLQSGYLFIQTDKTIYTP GSTVLYRVFTVDHKLLPVGQTVIVSIETPDGIPVKRDSQSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQVFSAD FEVKEYVLPSFEVQLEPEEKFYYIDDPDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAI LRRQVLLNGVQPSRADALVGKSIYVSATVILQSGSDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDG SPARHIPVVTQGSNVQSLTQDDGVAKLSINTQNKRDPLTITVRTKKDNIPEERQATKTMQALPYNTQGNSNNYLHLSVPR MELKPGETLNVNFHLRTDPGQQAKIRYYTYMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLINANG QREVVADSVWVDVKDSCMGTLVVKSGGKEEKHHRPGQQITLKIEADQGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEK ADIGCTPGSGRDYAGVFTDAGLALKTSQGLETKQRADPLCPQPAVRRRRSVQLMEKRMDKVGQYSGDLRKCCEDGMRDNP MKFPCQRRAQFILQGDACVKAFLDCCKYITQLRQQHSRDSTLELARSDLDDEIIPEEDIISRSQFPESWLWTIIEDFKQA DKNGISTKLTNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYREAEDLK ARPWVELLYNPAFCSLATAKKRHQQTLVIPARSSLAVPYVIVPLKVGLHEVEVKAAVYNHFISDGVKKTLKVVPEGIRVN KTVAIRTLNPEHLGQGGVQRVEVPAADLSDQVPDTESETKILLQGTPVAQMTEDAVDGERLKHLIQTPSGCGEQNMIGMT PTVIAVHYLDSTEQWEKFGVEKRQQALELIRKGYTQQLAFRQKNSAYAAFLGRPASTWLTAYVVKVFALSANLIAIDSKD LCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFRDTREKDVSLTAFVLIALHEAKDICEAQVNSLGRSINKAGDFLENH YRELRRPYTVAIAAYALALLGKLEDDRLTKFMNTAKEKNRWEEPNQKLYNVEATSYALLALLARKDYDTVHPVVRWLNEQ RYYGGGYGSTQAITQIHPLLCHGQQATFMVFQALAQYQKDVPDHKDLNLDVSIQLPSRNSLVKHRILWESASLLRSEETK ENERFTVRAEGKGQGTLSVVTVYHAKLKGKVSCKKFDLQVSIRPAPEPVKKPQDAKGSMILDICTRYLGDQDATMSILDI SMMTGFSPDIDDLKLLSSGVDRYISKYEMNKDSNKNTLIIYLDKVSHTVEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLD ETCIRFYHPDKEDGMLSKLCHKDTCRCAEENCFMHHLDEEITLDGRLDKACEPGVDYVYKTRLVQKKLEDDFDEYIMVIE QIIKSGSDEVQVNQQRKFISHIKCREALKLKEGAHYLVWGVSSDLWGEKPNISYIVGKDTWVELWPDAEECQDEENQKQC EDLANFTENMVVFGCPN >XP_023100060.1 complement C3-like [Felis catus] MGPASGPSLLLLLLLPILPLAPGDPMFSMITPNILRLENEETVLLEAHDLENNIAVAVTVHDFPVKKQVLSSENSALTKD NNHMSTVKIKIPASKELTSEKGKKFVTIQADFGSTVVEKVVLVSFQSGYLFIQTDKPIYTPGSTVLYRIFTVDNDLLPVG RTIIVSIQTPDNILIKKDSLSSQNQVGILSLSWNIPELVNTGQWKIEAHYEDAPQQVFSAEFEVKEYVLPSFEVQVEPTE KFYYIDDPQGLEVTITARFLYGKNVDGIAFVIFGVQDGDQRISLPQSLTRVQIDDGSGEARLERKVLLSGVQPSGADALV GKSLYVSVTVILHSGSDMVEAERSGIPIVTSPYQIHFTKTSKFFKPGMPFDLMVFVTNPDGSPARNVPVETQDSRARSLT QADGVAKLIINTPNKPVPLPITVITRKDGILESRQATSSMLAQPYKIMGSCSNYLHLSVPRVELKPGEDLNVNIHLRIDP TTTKQKDIYYYTYLIMNKGKLLKVGRQMRELGQDVVALPLTITEDFIPSFRLVVYYTCLNSNGQREVVADSVWVDVKDSC VGKLVVKGGRKEERVHLPGQQMTLKIEGDRGARVGLVVVDKGVFVLNKKNKLTQSKIWNVVEKADIGCTAGSGKDYAGVF TDAGLAFQTNTNLQTPDRTDPECPKPATRRRRSVMLMEKRMDKVGQYPRQLRKCCEHGMRENPMKFSCQRRARFIQHEAS CVKAFLDCCNYITQLRLNHTRSAHLGLARSDLDEDIIPEEEIISRSQFPESWLWRIEELSEPEKDGISTKTMNIFLKDSI TTWEILAVSLSNKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYQDVGELKVRVTLLYNPAFCSQATAR KPYQQILEIPAKSSMAVPFLLVPLKVGLHDVEVKAAVYNRFLMDGVKKPLKVVPEGIRVNKTVAVHTLDPENRGQNGVQR EEVHAIDLSDQVPDTDSETRILLQGTPVAQLTEDAIDAERLKNLIVIPSGCGEQNMKSMTPTVIAVHYLDQTEQWEKLGP TKRKEALQLIEKGYSQQLAYRQDNSAYAAYLDRKPSTWLTAYVVKVFSLASNLIAIQADVICGAVKWLILHRQNPDGVFQ EDAPVMSQAMTGGYQENEEKDVSLTAFVLIALEEAKDICKQRVNSLEKNINKAGDYIEFHYRNLRRPYSVAIAGYALARL GRLKEDLLEKFLSTAKEKTSWEEPGKDLYNVEATSYALLALLVLKDFDSVRPIASWLNEQRYYEGGYGSTQATFMVFQAL AQFQKDVPDHKDLNLEVSIELPSRSSAIRHTILWESASLQRSAETKKNEDFVVTAKGKGQGTLSVVTMYHAKLKSNHTCK KFDLRVDIRRAPEDVKRPQEALDTMILDICTKYLGEQDATMSILDISMMTGFSPDTGDLDLLSNGIDRYISMYELNKAFS NKNTVTIYLDKVRLPMGI >OWK12416.1 C3 [Cervus elaphus hippelaphus] MQPTSGPSLLLLLLLASLPMALGSPMYSMITPNILRLESEETVVLEAHGGQGNIPVSVTVHDFPAKKQVLSNENTQLNND NGYLATVTIKTPDGIPVKRDSQSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQVFSADFEVKEYVLPSFEVQLEP EEKFYYIDDPDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILRRQVLLNGVQPSRADA LVGKSIYVSATVILQSGSDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTQGSNVQS LTQDDGVAKLSINTQNKRDPLTITATKTMQALPYNTQGNSNNYLHLSVPRMELKPGETLNVNFHLRTDPGQQAKIRYYTY MIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLINANGQREVVADSVWVDVKDSCMGTLVVKSGGKEE KHHRPGQQITLKIEADQGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTSQGL ETKQRADPLCPQPAVRRRRSVQLMEKRMDKVGQYSGDLRKCCEDGMRDNPMKFPCQRRAQFILQGDACVKAFLDCCKYIT QLRQQHSRDSTLELARSDLDDEIIPEEDIISRSQFPESWLWTIIEDFKQADKNGISTKLTNVFLKDSITTWEILAVSLSD KKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVRVELLYNPAFCSLATAKKRHQQTLVIPARSSLAVPYVIVPL KVGLHEVEVKAAVYNHFISDGVKKTLKVVPEGIRVNKTVAIRTLNPEHLGQGGVQRVEVPAADLSDQVPDTESETKILLQ GTPVAQMTEDAVDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQQALELIRKGYTQQLAFRQKN SAYAAFLGRPASTWLTAYVVKVFALSANLIAIDSKDLCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFRDTREKDVSL TAFVLIALHEAKDICEAQVNVKKNRWEEPNQKLYNVEATSYALLALLARKDYDTVHPVVRWLNEQRYYGGGYGSTQASSP HILHPGNCSPTSSGLISLLKKATFMVFQALAQYQKDVPDHKDLNLDVSIQLPSRNSLVKHRILWESASLLRSEETKENER FTVRAEGKGQGTLSVVTVYHAKLKGKVSCKKFDLQVSIRPAPEPEPRNYTPPPAPPPSILLFSVFLVKKPQDAKGSMILD ICTRYLGDQDATMSILDISMMTGFSPDIDDLKLIPQFLHHFPTPMLDFLPCQPSPDQPPPSSQVSHTVEDCLSFKVHQYF NVGLIQPGAVKVYSYYNLGSDEVQVNQQRKFISHIKCREALKLKEGAHYLVWGVSSDLWGEKPNISYIIGKDTWVELWPD AEECQDEENQKQCEDLANFTENMVVFGCPN >XP_018109218.1 complement C3 [Xenopus laevis] MGCGLLSLSLLLLVSGSYAQTPCTLITPNLLRVESEETIVIDAQGQNAPFEAEVIIQDFPQKKLNLVSTKVPLNVNNGFL GTATLKIPSGDLSKDTKSKQYVYVSVKSNVCALEKVVLLSYHSGYIFLQTDKTIYTPGSTVLYRIYSMNYKMQPISKTLI IEFLTPDGIIVKRDTILQDSKSGIISQSHKLPELLSLGVWTISAKYEDTPQQNYTINFEVKEYVLPSIEIILKPDTNYFY ADAESFGVDIQAQYLYGKHVDGYAFVLFGIRKDNVKKGIPESLTRVRIDDGEGRAELKRKDLVKYFEKPEDMLQFGLYVT VSVVTETGSDMVEAEIEHISIVTTPYKILFTKTSKYFKPGMPFDMMVYVTNPDGSPARRIPVVVEPGNVEGTTQGDGTTR LTMNTPANINVLPITVKTRDPTLPPLRQATATMTATAYRPSKAHGNYLHISIAGSDIKPGENIPVNFNIRNTDAGVQNQI QHFTYLIMSRGRILKVGRQQRQPGQPFVTMSLPVTDTLIPSFRIVAYYIVNVGGSRDVVSDSLWVDVVDDCMGTLTVTGD KDRDNAIQTPGSPMKLKLRADHKAYVGLVAVDKGVYVLNSKFKITQKKVWDSVEKSDIGCTPGSGANSEGVFSDAGLALQ TSFGINTAQRSDAQCPAPAQRRKRSSVALIEIKAGKASEYKDKAKKCCLDGMQENLMGHTCDRRSRYILDGKECVDAFLD CCRYYEKKREAEKLSKDDDTLGRSDEDDEYMLDSDIVSRTEFPESWFWKVEQMAEKPDVNGISSKTLNVFLKDSITTWEV LAVSLSENKGLCVGQPYEIKVMKDFFIDLKLPYSVVRNEQVEIRAILYNYRNDRIKVRVELTHNPEFCSLSTAKKRYRQE VWIGGLSSTAVPIVIVPLTLGLHDIEVKASVSAQSGFFGADGVRKKLKVVPEGMRIAQDVKTVILEPEVKGKGGVQEEKV EALNPKNVVPRTDIDTTITLQGTPISQMVEDAIDGNNMNHLIVVPAGCGEQNMISTTPSVIATRYLDASGQWERIGVNRR EQALKNMRQGYAQQMAFRKPDNSYAAWKDRPASTWLTGYVAKVFGMAQEFIDIEANVLCGSVKWLILEKQKPDGLFQENA PVIHQEMVGGITTGAAEGDSSLTAFILIAMLECQRTCNEHVNNLQVSIDKASSYLVGQYPGLKKPYSIAITSYALALAGK LPNTNKLLSASIGNTHWEEPGKRFISLETTSYALLTLLKMKEFDLTGGIVRWLNEQRYYGAVYGSTQATIVMFQALAQYQ TDIPSVNELNLDVSLHLPERQQPLTYRINLENALLARSAETRLNQDFVVKAKGKGQGTMRVVTVYHALVTEKERKCLNFE LSVNVKEVQLARPPEGAKATVSIEACARHLKNVDATMSIIDISMMTGFSPDTDSLDRLMKGVDKYISKYEVNKGANDKGT LILYLDKVSHIDEECVKFYAHQYFEVGFIQPASVTVYDYYTPDNRCTKFYHVEEGSALLGRICQGDICRCAEENCFMQQQ IEGKITADMRVNMACAPGVDFVYKATLTELQPSDNYDNYVMTIKKVIKQGTDEDPEDKTRNFISHIKCRKALNMQLNRDY LIWGVTGDLWRQPDGYSYIIGKDTWMEWWPNERECQQRENEDLCDDFETVSDNLEIVGCPN >XP_040202590.1 complement C3-like [Rana temporaria] MGDRTLCLILLSYLAGSSYGQTQCTLITPSVLRVDSEETIVVDGHSSTFEVEYFIQDFPARNLMLARGKINMNGGNKHLG TAKVTIEGKNFIKDPKKKQYLSISVKSSNPPCNIEKVILLTFHSGYIFIQTDKPIYTPGTSVQYRLYPVNFNMQPTNKAV QVDILNPDGILVKNEQLYPDVTGIISKTYPLTDVPSLGVWTISTRYDGTFQEYTTNFEVKEYVLPTFEVKIKPDRSFMYA NDETFSVAIEADYTYGKTVSGNAFVLFSLKKGDERKTVADSLSRIVIDDGKGRATVKRADLLKILKKTEDILEYRLHVSA TVITEAGSDWVEAELDNIYIVTSAYKILLTRTSKYFKPGMPFHFMVLVTNPDGSPANKIPVVVNPGSGQGVTEEDGTSKL IVNTGSNRTPLKITVKTTIGGLNEKLQASAETTITPYQPQSGLGNYLHLTIDTNVAKPNKQIFISFHILTSSPADQDKVQ HFTYLILSKGRIISVGKQKRDQGQGIVTMSLIVTKDLIPSFRIVAYYTIKKELVSDSLWVDVVDECMGTLEVDSKKKTAA PSDLIPLTLKADHDSYVGLVAVDKAVFVLNKKYKITQSKVWDIVEKSDIGCTPGSGANNMDVFYDAGLAVESNFGMVTKQ RSDPSCDAAKKRKRRSSAALIEMKNQKALNYNENLERQCCHDGMTSNPMGHSCDRRAKHILKGDKCVQVFLDCCKYIELK IKIEKEQDKDLERSDSEGEYMKDEDITVRSAFDESWLWNIIKITEKPDNNGVSTQQVKNKYLKDSITTWEVLAVSLSKTN GICVAKPLEIQAFKSFYVDLRLPYSVVRNEQVGIRAVLYNYENEVLKVRVTLTYNPKFCSLSTPSKKYTKDVIVKESSTF TVPLIIVPLEVGMHDVEVKAAVLGGFVADGVRKQLKVVPEGVRKVETILSEDLEPERKGRSGEQVVNVKSLKNKKIAPQS SISLIVNVKGSPIADFIEQSIDGKNLNHLIIIPTGCAEQNMMKLAPLVIATLFLDKTNQWDKVGLHRRTEAISHMQTGYA TQLTHRAKDGSYTALQGSPQGTWLTAYIVKIFSLAKRMIHITDDVLCGSVRWLVLSMQKPDGMFQEHFPIGSQYYQKTRG GLGSSPDPNVAITAFVTIALLESQNYCKDHVSNLQRSIDKAVQFISEHYGKLTRPHSIALTSYALARAGKLSDSTKLMSV ATGKSQWNDPDSKFWSSQEYGRYISLEATAYALLTLLQIEEYDLADSVAQWLIRSHVDGEQYGTTQTIVVLFEALAKYQE ARENKMVLDMDVSVNLPERKDPSKYRLNLQSNLNARSDETNINSDFVVKAKGKGRASLTVTAVYYEIVTEKESECNHFDF TITARDEPHAKRPDNALGTMSVEVCFRYRGDKDLTMSIVDVTMMTGFSPDVDDLKRLQHGVDRYISQFEINKGAKDKGTL IIYLDKISHTEEECLKFNAHRYFEVGLVQPGSVTIYDYYSPETRCTKFYHTVEGDNLYGRICQGDVCRCSEGNCLMLQDP KKSYSALERKDTACQAGMDYVYKATLLETEYANDYDRYVMHITNVYKNGTDENAQGQKRTFISHIKCREALKFKKGLDYI IFGSFNDVWQTAANTYTYIIGSRSWVEWWPNKRECQNEEYEELCDDFYSLSEDITMFGCGV >NP_001098552.1 complement component C3-1 precursor [Oryzias latipes] MRRALQLLLASLALVSLMSLIDAGPLNLMSAPNLLRVGTPENIFVECQDCSGANQPVTISVKNHPTKAKTLATTQVTLTN DNNFQGFGQITIPPGDFSKDPSVKQYVYLEAAFPGRTLEKVVMVSFQSGYIFIQTDKTLYTPNSKVYYRMFGVTPRMEPL ERLNDAQTDTSISIEIVTPEGIILPLDPVSLKSGLHSGDYQLNEIVSPGLWKIVAKFQSNPQESFSANFEVKEYVLPSFE VKLSSLRPFFYVDSETLEIDIKARYLFGQEVNGNAYVVFGVMDQGQKKSFPDSLSRVPIENGEGKVVLKREQITKTFQDI NQLVGTSIFVSVSVLTESGSEMVEAELRGIQIVKSPYTITFKRTPKYFKPGMSFDVAVEVLNPDESPAGNIPVVVTPGPV RGFTAANGMARLTINTATQDERLSISAKTDDPGISLNRQAEATMQANQYSTNSKTYIHIGVDTPEVKLGDNLKVNLNLNK QPGGNQDITYLITSRGQLVKFGRYKTRGQVLISLIIPVTQEMLPSFRIIAFYHPSDNEVVSDSVWVDVKDSCMGSLTLEP KTPAASYEPRKMFSLKVSGDPGATVGLVAVDKGVYVLNSKHRLTQKKIWDEVEKFDTGCTPGGGKNGLSVFFDAGLLFES STASGTVYRQEKKCAAPSRRRRASTIMDVRTTLLSQYKEDLQRECCLDGMKDSPVSYTCERRSEYIMDGGQACVDAFVTC CKEMEKQQLEKKEESLQLARSETDDSYMDSNEIVTRSNFPESWLWSDIILPQCPPNTPNCGSTSSVKNVPLQDSITTWEF TGISLSRTHGICVGESLEVIVRKDFFIDLRLPYSAVRGEQLEVKAILHNYRPELITVRIDLAEEKDTCSAASKRGKYRQE VNVGAMSTRSVPFIIIPMKEGTLPIEVKAAVKDSYLSDGVKKDLRVVPPGVLVKAIESTILDPAHKGKNGEQVEVLNSNI PKSNFIPSSPTSTQISLTGREQVSGLVENAISGKSMGTLIYQPSGCGEQNMIHMTLPVIATIYLDKTNQWEAVGFQKRAE ALQHIKTGYTNELAYLKGDGSFAVWADHGSSSWLTAYVIKVFSMANNLVAIKKEHICDAVKFLILRAQQPDGLFTETGKM YHGEMIGDVRGSDSDASMTAFCLIAMQESRSLCSATVNTLPGSIDKAVAYLEKRLPRLTNPYAVAMTSYALANEGKLNRD ILYKFVSPELTHWPVPGKHLFTLEATAYALLALVKTKSFEDARPVVRWFNQQQFVGGGYGSTQATIIVYQAVAEYWANAQ EPEYDLKVDILLPGKSKPDKYEFNRENSYATRTSKIKDINKDIKVKATGSGEAVLKMVSLYYALPEEKESDCQKFDVSVQ LLPAKNIGNQKVYKLQIEVLYKDSNRDATMSILDIGLQTGFTPNLDDLKALSGGRFPLISKYEMNTALSERGSLIIYLDK ISHTRPEEISFRVQQTMEVGVLQPAAVSVYEYYEQTPCVKFYHPEREGGQLLKLCKDDECTCAEENCSMQKNGQISNDER TSKICESTESSKIEYAYKVLVEDVVQKPSIDIYAMRVQDSIKEGSTDVGPRGKLRPFLSYPHCRDALNLQKGKTYLIMGS SRDIHKDEKQLTYQYVLGERTWIEYWPTAEECQGDEHRATCLGLDEMLEQFRVFACQQ >XP_030274930.1 complement C3-like [Sparus aurata] MGSSRRTCVTNLWLLAFLAFFSLTDGSPLQVMSAPNLLRVGTTENIFVECQDYTGGNIPVEIIVMNHPTKVKRLASTTVT LTNENSFQQLAQIMIPTGDFSKDPSIKQYVYLQARFPDRLLEKVVMVSFQSGYIFIQTDKTLYTPESTVLYRMFAVTPLM EPVERDEETKSDASIAIEIVTPEGIILPLDPVSLKSGIHSGDYKLGEIVSPGLWKVVAKFHNNPQQSYSAEFEVKEYVLP SFEVKLTPVSPFFYVDSPDFTVNIRATYLFGEEVDGMAYVVFGVMQEGQKKSFPGSLQRVQIAKGIGVVTLKREHITQTF KNINDLVGSSIYVAVSVLTESGSEMVEAELRGIQIVTSPYTIHFKKTPKYFKPGMSFDIAVEVMNPDETPAQGVAVVVDP GEVEGFTAANGMAKLTINTEAGINSLRITAKTKDPLLTRERQASATMTALPYTTKSNNYIHIGVDTAELELGDNLKINLN LNRQSNQAKDITYLILSRGQLVKKGRYHTRGQVMISLIVPVTKEMLPSFRIIAFYHTDGNEVVSDSVWVDVKDSCMGSLK LESSRPAPSYEPRRMFRLKVTGDPEATVGLVAVDKGVYVLNNKHRLTQKKVWDIVEKYDTGCTPGGGKDGMSVFFDAGLL FESNTASGTPYRQELKCQARSGSRRKRSNTIMNVTTSLVSKFEDPLERECCSDGMMKTPLSYSCETRSEYIGDGAACVKA FLHCCKEMENQLADRNEESLQLARSEEDDNSYMDSSEITSRTQFPESWLWSDIKLPACPRQTPNCDTTTFEKNVPLQDSI TTWQFTGISLSRTHGICVGEPLEVIVRKEFFIDLRLPYSAVRGEQIEVKAILHNYSPDPVTVRVDLIEEVDVCSSASKRG KYRQEVKVGPQTTRSVPFIIIPMKQGQYRIEVKAAVKDSSLNDGIMRMLRVVPQGVLIKSPKIVTLDPANKGVGGIQKEV INSEIPKKDLAPNTPTSTQISVTGREQVSALVENAVGGQSMGTLIQQPAGCGEQNMIRMTLPVIAATYLDKTNQWEAVGF QKRAEALQHIKTGYTNQLAYRKDDGSFAVWAKHKSSSWLTAYVTKVFAMANNLVAVQRHVICDAVKFLILNAQQPDGMFR EVGKVYHGEMIGDVRGADSDASMTAFCLIAMQESRTLCAATVNSLPGGIDKAVAYLEKRLPALTNPYAVAMTSYALAQEN KLNREILYNFISPEMSHWPVPKGRVYTLEATAYGLLALVKAKAFEDARPVVRWFNKQQKVGGGYGSTQATIMVYQAVAEY WASAKEPEYNLDVDILLPGRSKPDKFNFNRNNHYATRTSKTNDINENVTVTATGSGEATVTMVSLYYALPSEKESDCQKF NMSVQLIPDKNDGVETSYKLRIEVLYKDKERDATMTILDIGLLTGFTVDRNDLDLLSKGRARIISKYEMNTLLSEKGSLI IYLDKVSHTRPEEITFRIHQTFKVGVLQPAAVSVYEYYEQTPCVKFYHPERRAGHLLRLCRGDECTCAEENCSMQKKGKV SNEQRTAMACESTAISKIDFVYKVRLEEFTDSQSTDIYTMRVLEVIKEGSYDVGPQNQVRAFLSYQHCRESLDLTEGKTY LIMGTSKDIHRDEQNQSFQYVLGERTWIEYWPTEAECQTDIHRPTCLGMEELVQQYALFGCEH >XP_015824898.1 PREDICTED: complement C3 [Nothobranchius furzeri] MRRTNLLLLASLAFASLMSLAEVKPAPLKLMAAPNLLRVGTAENIFVECQDCDGGDISVDIKVMNHPTKTKELAKTTVTL SNNNNFQQLGEITIPPGDFSRDPTVKQYVYLQAKFPDRELEKVVLVSFQSGYIFIQTDKTLYTPNSKVYYRMFGLTPEMK PVEGQNQADASIDIQIQTPDGIILPLDPVSLTDGIHSGDYQLSEIVSPGLWKVMARFQSNPQQSFSAEFEVKEYVLPSFE VKLLPDTPFFYVDSDDFRVSIKATYLFGREVYGTAYVVFGVLEDGVKRGLPSSLSRVPITNGEGQVTLKRSHLTDTFPEI HTLVGKSLYVAVSVLTEGGSEMVEAQLRGIEIVTSPYKITFLKTPKYFKPGMSFDVVVEVVNPDGSPANNVVVEVVRHNV QGLTAPNGVARLTINTQGTDTSLEIIARTKAPNLPDERQASANMVATPYSSNTQRYIHIGVDTAEVKVGDNLKINLNLNN QPGHQTDITYLITSRGRLVKSSRYKTKGQSLISLILPVTKELLPSFRIIAFYHPADNEVVSDSLWVDVKDSCMGSLTLQS TRPVPSYEPRKMFNLKITGDPGATVGLVAVDKGVYVLNNKHRLTQKKVWDIVEKYDTGCTPGGGSNSMNVFFDAGLLFES SISLGTPYRQELKCKTTARRKRATTILSVRTNLMSKYNNERQRECCLDGMKEIPLSYTCKRRAEYILDDPDCAEAFVHCC NEMQTKRAENKEDELRLARSESDDSYMDSQEIVSRTNFPESWLWSDIKLPACPRPNCESTSFVKNVPLVDSITTWQFTGI SLSRTLGICIGDPLEVIVRKEFFIDLRLPYSAVHGEQLEIKAVLHNYSPDVITVSHKHGLMHLIDLNSLVVPQGVLVQTS QDVTLNPTEHGQNGQQVEKLNSNIPRNDLVPNAPTRTDISVTGREQVSGLVENVLSGSSLGTLIKAPGGCGEQTMISMTL PVIATLYLDKTNQWETVGFQRRNEAIQHIKNGYRHELIYRKTDGSFAVWAHDKSSSWLTAYVAKVFAMANTLVAVESEHI CGAVKYLIINAQQPDGMFREIGRVYHGEMIGDVRGKDSDASMTAFCLIAMQEARTVCTQHVTSLQSQIDKAISYLEKHLP TLTNPYAVAMTSYALANENKLNREILFKFASPELNHWPVPGNKIFALEATAYALLALVKSEAFEDARPVVRWFNQQQFVG GGYGSTQATIMVYQALAEYWSKANEPEYNLNVDILLPGRTKYDKFNFNRENQFTTRTSKFNDINQDVNVIATGSGEATVK IVSLYYALPKEKESDCQQFNMSVDLIPEKITDDERTYRLRIEFLYLNKERDATMSILDIGLLTGFTVDNDDLNLLSKGPA RVIDRYEMDSVLSERGSLIIYLNKVSHTQPEEITFRITQPAKVGILQPAAVSIYEYYDRTHCVKFYHPQRRAGQLLRLCK ENECTCAEENCSMQKKGDISNDERLAKICESTETSKIEYAYKVSVENVDFDLSADSYTARVIEVIKEGTTDVGSLGKLRT FLGYQHCREALQLKQGRTYLVMGSSKDIHRDEQNESFQYVLGERTWIEYWPTSEECQSHEHRPSCLGLEEMVDQYNDFPC QQ >XP_038046850.1 complement C3-like isoform X2 [Patiria miniata] MAQYFIVAPNLVRVDVQETILVSVLGTGENQIPVTLYFQLTGSNDRISETTVFVRQDESQEARLRIRRDQLPQLQTSGQQ FVTLVASANTAQLSIDDRRVILLSYQAGFVFIQTDKPLYTPKQRVDIRVVALDQDMVPVNNEMQVDIISPDDIIVERYKQ RPVDGFLTLSFVFPSNPVFGNWSVSAYYGHQFKASSTVQFEAKEYVLPKFYVEVAPQSLYIVPETQNLISKVTARYIFGE PVVGNFYVKYGVLEDDGSLMDLQSKEGRLNEVGEAFQDLDMNDVKVENWAETLMGKRLVIQAFVTDTATGETINTNNTQV TFSRTPYKFNWDLTQRYFKKGLSFSVKANVQFMSGLPAEDVPVIASATALQGGRRVDLEGAQAGAQAGGGREHLEKISGP QGEVDFRLDVPAAATEITITLRTNNPDLVNANTEGTITVLAQASSNNEYLVVRVPSGDIRRVQRIGRQSTVEVQLTHPDN VGVLNYFVIAGGRIVHKGAKNQVNLNTALGFEVTHEMAPSSRVVAYYTDANGNVVADALLIDVEEKCKNPIGLSFLGLPS EGSTYKSERSGQNVQLEILAKEDTNVGLVAVDEAVFKLRNYHRLTQKKVFKRMAGYDLGCGPGGGQTSATIFKNAGVTVM TNAQLDVPHREALGCPEPVRRARRSANDTEREQILSNYEGVNREYCEKGMRELSGSVQLTCAQRAKLMAGRKGLQVDSPE IRAFFDCCSVLESSSDRGRVDAGAGGVNLEDILVRSNFPESWLFDNVITQSLRSDDDDGRVLYPTTLPDSVTTWVIEAVG VHMREVHEMCVAEPIKLEVRPPFFLDIGMPYSVQRFEQIEIVASVFNYGDDELEVTVYLRGKEGLCSIAQPGEYSEGITI QVEAKKPASVKFVIVPLEVKNIPIEIVAMDASGQHRDAIEKDLTVRPEGYEKKISVPVTLDPANYRGSPAKQDGGADQFY FHSQNWGDQGEEKQIDFIRYSVNRNAIPGSHKARMSLVGNVLGSVIDTVLGGLDKLLRIPGGCGEQTMLGLAPNVYVYTY LKHTDQFTAALETSSERYVFNGVKHELTFRKNDGSYAAFTSRPSSTWLTAFVAKIFCKAKDFAFVDDSNICKAMEWLITQ RQSQDDGSFTERNAVIHKEMSGGVQGKASMTAFVLISLLECECDAINKDDSVAAATALLEDELPDLTRPYAIAITAYALA LANSIRAQEAIQMLKDIAAYNAVSDSRYWAADDSSFGGGQKPYWYSARPKAIEVETTSYALLALLQMEEIQYTHAIVNWL TNQENYNGGFVSTQDTVMALQALSEYAYKVQQYDIDINCEVKCDESEFDEDFSLNPANALVREQRNIDVPDMSQEMNVFI STEGAGMGQFKFEATYYIPEPDVTECDFDLLINEDENLQLDRPEDDNKEYLSYDIQVRYLRGEKTGMAILDVGLYTGYKA VQEDLQTVMDNSGGRVERYEETDHSVVFYFEDIPGLEAIRIQFRAEREFNVGKVQPVAVHVYDYYNPTEECVKFISPKEG SNLLGKLCVEDTCVCAAGKCAVDPIKKGRDYKVYDMTQMACASKAHFAYEVTVTDVEDKGNFQFYTMTIDAPLKQGLDHV VKDATRVFAKSKSCDTPDLQMTKYLVIGSGGLPTKDDVGQDIYKYVIDDRTFFYEYPTILQVNKSKKWQRIHAKLTELKQ ELVNGEGCAL >XP_030852887.1 complement C3 [Strongylocentrotus purpuratus] MGVSITMGSFVLIFVIAISASLVPGGVTQSSPATFFVTSPNVFRVDVPESVVVTLIRSTPNVQNVQVRVSLRRPGSGVHF SEDTRAVSPGSSQLFTVEIQADNLMRNEGDFQHMVLKAESLDPSYPFQKETEILVTLQSGYVFVQTDKPIYTPNQDVIIK VMSLDQEMLPSDRELHVEIIDPSGTSVKRLRQTQALPSGFLSGEYRFHSHPALGIWTVSAFYGPEFLVESSATFVVKEYV LPTFSVSIETPKYILAGAYSVVSTINAQYVFGKPVLGRYTFKYGVIQDGTVQELGERQGLIGDTGRAVVTLDDLSTDFDG PDWFDRFRGRHFHAKAIVHESATQFSEASINTKAIFVDSPYKFSRKRTVQYFKAGLNLQVNLDLTFANGDVATDVPVSVI ATARFPGGREEPLRRTDIYGSQVDLRSNTDDQGGVSMDFGVQSSIRSIHIVASTHDPQYPNNQADMSFGVSLADSANGND YLVIRPRYADYRSLNVDVTTDFLVQRIGTTGNEDIDLHFLCITGGKIVLQGVQQRISAFGTNLPITIRSNMVPRMRLIVY YVTMDGSVIADSLLLGVEEQCRQNQEVSLEILPRHVGPERTVYEPNGEIRVEVTAPNNSYVGLLAVDKAVYLLRNKDRMG KRKMYDWMRSYDTGCGPGGGQNTAQIFKDSGMTVLTNAGLDVAIREEIECVDEPTRKKRSIDRDQQCLYDPTYLVNCLAD KPRLRRSGGGVGYQNGDVRVREDFKETWFFDVVSMPEDGSPYLYPISTSSSITDWHLTAVSFSPTQGMCISETTVSVFQD FFIQLHLPYSVVRLEQTQVIATIFNYGIRGFEINVNFTVEDGLCTAENPTIRHVFVESRRAASAAFIVRPVEVGEFQITV TAGGSVNKRDIVRKTLLVVPQGVMKRKGRSVILNPGRVMFSDDVTTPSPNNSFAQGTTLFGENQQFEQMTISLPEDSIPD TESCSVKLIGIPTETTATDPIGGLDHLVRRPRGDGEQTMIFLAPTLFVYQYLIAVGSDTVEQEARIYDYIADGVVRELTY RQPNGAYAAWTHRPGSTWLTAFVVKVFSQANRFTWVDPVHVEGSINWLIDNNQLPSGAFQESRQVFYQEMIGAVQGETSM TAFVLISLLESRNLLVPANQKIDDAIGNATEYLVTHVEDIDRVYDKAIVTYALALAESPSMRIANDYLWGDRNEDDTGAV SFTPDVANYRDGSQPYWLQRRPSAVEIETSGYALLAQIALHDYQKAGKVALWLSNQQNYGGGFVSTQDTVVALQALAKYT ERPEFNTINMDCELATEQITVHRYHIGDDYVQEEVDVSQSIGRSLTIGCRGTGIAKAYVELRYNTEQSDIDTCPFHLNTS AVEIDSNALRSQNVKGLRITVCTSYNGDGTTHMSILDVGLYSGFNAVEQTEPEIEGLEEMVNGSEIISSYEASSRSVIFY LNQIPDDEDLCFTFSAKSYVVVGNVQAAAVHLYDYYDPDKSCTISYKPGPGSALLSTLCSESECICTGGSLDYCNIDPCP GPYSIFELERAACASHSSYALKIRIDTEEIQEGFRIYRFTVLNPIKTGDEDVPHQAQRQLFINEDCDCPKVKGRNIGGTF LLVGQKSLKYTTEQGEESFRYVYGPTSKLEVWLQTRRPRNAAVFDKLEQFENEMGIETACSNEI >XP_031565662.1 complement C3-like [Actinia tenebrosa] MITQFKENAMFTDSKMLLTLLTIALLMVGCSSKPSYVITAPNIFYVGVPQPIHVALFDVKWSHTIELELRVFLSYGETKV IASQRDRISADNGKLFSLTVGPEVSKFQSSQDRGFVYLLSRIKGPELHISKNTKVNVSYSDGVILIQTDKPIYTPKQTVK IRVVPLGFDLMPSAKKINLVVKNPHGIGVRQWESLNTTLGFISKNIDIGSYALAGIWTIEAYYGHQFLYNASSRFEVREY VLPRFSVKISNPLYILPTLDSFKVKGTAKYTYGKPVQGTATVRLSIAGNPQEKAMSLSTSKIKLVNGEFEHPIKMDRIKT KLREKWFPEGYRLHIEADVTEKSTGKTERAVERSVYFVTTPYLIEYVNTARYFKPGLPFSIVVIVKFTNGQVARKIPMKV LVEAFKTDGRKINASDPKQIQGSGFNWNRANTDDNGRAEFVINIARQVKELQIKVKTNLQNIPKEQNAFKELVMDASESH ELMKLRQTNKPARVGTNAVCDAVLTSKTVDQLTYFVISRGQIIYSATIKKLLGIITTISFKVTSPMSPSSRLFAYYVSKE TGRVVSDSILLEVEHKFPNPIFLKDSDRRNEEPPSMPYNIKIVGTVGTKVGLLGVDQSVYLLSKSNILTADSVFKKQEEL DLGCGAGSGRNSEDMFRNAGMVVLSSDIEVSGEQKCKGEHKRERRSIEEHRDFCCSLGNKTDTIKRSCFRRLKDLDVGIY NAKQRYDCRKTFWMCCIHKFGRNESGIFARARSGVDLEALDFGDEQQEDDALNIQTRQYFPETWINKELTISQHERNGEC RALLSQELQHKCGSAVLPVSLPDTMTTWVVQAIGVSSSAGFGIAKPLHITTFKPFFIYLSMPYSVQRGEEITILATLFNY KNYDVSVHLFLKGDQGFCSAAQPGKMTKLTTSKINIPPQDTVAFPITIVPIKFGKVPIEVIAVGDIGDDRVLKTLNVVPE GIEERLTQSYVLDPQELLKGRKEREENQQNKAEKLSFQSTQAHKDFKQKNKIKLDIPKNAIPGSISAKAYFTGNMIGQAL TNLAAGQMVSLLQMPDGCGEQNMVRIAPNVYILHYLKKTNQMTPELEKKKEKFIQEGYIHELNYRKKDGSFALFKREYNK GSTWLTAFVLKVFCQASKLSGVNIDRNVLCQSAKWLIGNQRQDGAFVEHANMRSIQGGVYTSDVTLTAAVVIALKQCQCG MAEVNSAVERAVGFIEKNVTTLADAYSLAITTYALVLANSPERFRANQKLIQKATYNQGSSNRYWETGSKARNIETAGYA LMAQVALNRFEYAGPIVVWLTKQRSFGGGFVSTADTCVALESIAKYSEQRQKFQLDLRIRMKNKIMRITKNNAFMQQEAD LTEQTGDEVGIQTSGSGVGQMQVDIKYNVPYKENERCDFDVKVIATEEGSGRFISTTSSARNNVPARSRSRRALKAKSAK SKKRKDKNQAKKGKPGKSKKNKKRRKNNRKKNQKKHQKKNQRKNKRRNKGKSKKREKNNRKPQSIDIPKKLVLRVCTKYR KSGQTGMAIIEVGLVTGFSADEDTLIKLVEKKNNSIERYELSDRAVVFYVNQIVNSRRICIAFHLIRIFDVGIIQPVPIK VYXYYEPDTKCTLFYNLGSKRRPVGSCKKEKCKCTQGMCAEPDPYINNIDDLINEVCNVYNYAFKGKVVGIDENTDTNPM AMTYQINITQIIKQGSSIFQTQKAYLFNKPGICHYPDFEFEDEVFIMGKNKNGVQFLDRDTFVKTLSRRQRFVNKIAKHI RHGKCT >XP_039271128.1 complement C3-like [Styela clava] MKLLQLCMQLFIAVLCTRTSFGQNHLLIAPQILREGVRETAVLNLYNIDGRIDVVATVKLEGVTNFEIKNEDATKPIIMK IKYDKPPGVLPSKRRQYVELLVSAKQGNKKVYSGQLRMRLIESSGYIHIQTDRPIYRPEERVNVRVIALTQTQSPEVHRE VEIVIRIPLDNVGVEKKLLRMPKAKFIDTSFELPEYPVYGIWSIQARYTDEKVVRWSTTTFDVRPYVLPTFNVRVLLDDP YVLVKTDMSNEYIRGTITAEYSYGRKVSGPYFLAAKLNRPDIKSKFLFYQMPELRRMAKLRGGKQRFEIKATEVLTVIGD DTFDDLEKEGATIEIDVAVTGEAEGVVESDRSRPIMFVRSPYQLDISRMSKYYTPRTSFEIKIDVLDSVTNSPVKKVELI LAGPKICGTLDCGNDKCCSNGKCGECEPIVEESDENGQVNFKIGMDKDPVKRTYTIQTRKLGIPRENLAKLDFTLHPYIS SSGSYLQLSAVEKIAEVGDKNFGIDVWYKSAPSRISYVIMARGAIISTGVHIPKKGSVNTNIKIEVKGEMVPSFRFFVYF FSGKELLSNSLWIDVKDACKQELQVKVPAQVSPSQVFNVEYIGSPNAILGMSAVDRAAYFLYDKGRLTRSSVFEALNLYD EGCVREGGKNAQHVFEEAGLQVVGGPYSAKDDFTNHCEAKTLKRKKRSSPKNIVAKLEKEALERKCLMDGSWENLYGTSC VERAEAVRLKHSFECAEKFLKGCEDYLKLKRRSGRSIQANVAGFQAVANNVRSNFEENMLWATDVILGPDGKYTRGVVAK DSITTFEFDTVSMHEIDGFCVAPTQNVTIFKDTFVQLKLPYSLKRMEQAEIRATVFNYATTSKRVTVHVKMGEDICSHFR QGKFDDVITLEVDANEAEATSLVLMPLRVPDSKQVDIEVKITNEDNVDIDHVKRSILVLPEGEIKNDIKGTYAIDLKNKR PSYIDRFKIELRFPKRYIPGSRQCWIYPFSNYMGPIIEFDPVTKQPKNDIKNLIRLPGGCGEQTMLSMGPNVMAHKYLKL VGKMKDGSAEETGSIDKMQKGFANELKYRTSTAPIVWSVFPRRAPSVWLNAYVNKIFAQAKQFYTAMDVGPICTSINWLV DQQNPDGSFDTGGRVIHQEMHGAVGSTLSLSAYVMMSLVESQSICPQYTKKVEISILKATDYLENSENDRQMEQPYALSL VCFALSVSNPNNPFAKRMRKKLLSKINYSEDNRLAFWKGAPLKTIEGTGTHAYWYKRNAKAIDVEATGYALLSILYAQSG EKVTQNILDVTRKIVLWIIQQRDEKGGFSTTQDTVVGLQALAEYMIWSSTVEPPTRDVKIDLTISSATGSDWYDEPKRLH LDKSNENSTTPISIPSNVISGGELNIQARGEGEGTLSYRCVYRTLVDEDACHFDISVSTEEDRIPLGHVAQGDGAEILKL KLYISKPKGEPSGQSIVEINLISGYEVMEDTLVKLSETVDASIERYEIAKQKVFLYLSDITEVPKKLAFRISRSVYVGRP EPSTVTVYDYYEPSVRCSKFYNVPEQNLKLRTSSCTDKNGLGSEDICKCAEGGCLTCRTRKQQLENTGCLEGMDGECTIC HDPDNCFDLAGTACKSDYVYEVKVTSDGVEDPSGVFMDFAIQIVEVYKAGDDLDVDRNQNRNFSVRRDCFESCRDDKALV DKDGKKEPFLKKDRTLLMIGNGVEMNYEDDDNILKGGELPRPHYRLGAGIFVERIYPTTKCKKSKKKAEEKKCRKLKKKT PKSTREECLKHIAIHQSCNNLILLRKRITLGCDRERK >CAE1304902.1 unnamed protein product [Sepia pharaonis] MTNVEIQLKGSPRATVGLSAVDKAVYLINDKNKLTRKLVKDTMKLGDLACSPGGGLHVGQVFYHAGFVIMTQDLDRTPAT EINNILCSLKQITAEVSFGRYRRASDFCCISGRYRRGHNCKVAWQEFSYYRKTEFCRSAFMQCCNPAPELPPTRKVITSG EVDESENERTPSARLRQDAKSISPIFSLYFPESELFQEYRLNPSGLHKLNFTLPDSLTTWHIQGMSLSDTSPFCVSKPIS LTTFKNVITKLNFPRVVKRLEQIYIKAVVYNYKTHPINVKVNFHETKEICSHAAPGKPFPVKLSIPAKDIGVAGVVIVPL KAGNFTIHIEVYEVESNTLEIIEKVLHVKYEGVKKTNSFSLMLDPSGTYSGHKRHRRHIFKDVTIPKNEISASQKMQRII MKLTQPAEAIDGSAKGDIVITGNILGSTIQTTLKEPHKLLDKPYGCGEQTMIFLAPCVYILSYLNSTNQGSQVIYENATR YIRLGILREQEFRKMDGSYAAFDQNPSSVWLTAFVLKVFCQASEFEHVDSHLTKSAMTWLFQKQRLDGSFIEDYPVIHQE MVGGVNDRVMTAFVLISLMECGYKMHPVEIYRRKNEIDLAIRYLEKQMAVTYDTYDMAIISYALALADSSRKYEARIKLR SMAIENYDKGYLYWRVGGYSNVTAKKVSAWYHTEESYLSVEATAYALLTEMHYGEVEHVGPIVKWLIEQRNSAGMFKSTQ DTVMALQALAEYGIKTITPDINLFFNLTSSRAHLHKHLTVNKETSLWSHIIPDVPMNDEVLIESMGIGSAQMELNMWYYR PPTQRETCHFNVTHIIMPIQKDVRRLIKRGCPLCGESCRNLNGPILRNWDVSDQTICMKIYLRYLGTSDPGMVVLDMDLL TGYDTHEELLEQLKLDRLIAKYHKHGNSRLTLYFNTIPFNKEIEIKLLMFRTMIYMNRLMPAPINVYVYYNATESCTKFY QLSREKDLINLLCDSSKKVCKCAQRDCVTCYESMSELVNIKLKFLEKKSCAKEQIVMIVNMTSTFDSSGTAYGFVQEDLS KTDIPDLEEHVAIFQKGICHCPHVKVGEIYLIMANKRVRTLDESNQYRHKFWVDSSGLMINKKNQFVKGEIDIFEQKARS LSRQAFCG >XP_006565503.2 alpha-2-macroglobulin-like protein 1 isoform X1 [Apis mellifera] MNKLVFLVLFICSVTFLHCCDAASNVNRGYVFTAPKKLYAGEIETGCLSLHNLELPAHVHLELVFSFLEGQEVLASTSAV VKTGTETCLQLAVPSPIYRTAILRLKIKFDKYPDYVIKSETDVEIEHDSLLTFVETDKPTYKPGQDVKIRILMLMHDLKP WQKSIPEVWIENPSFVKVKQWTNVSTENGMAQLTFPLSPEPSLGSWHIKVMKKKPYPNLIHSTTFKVEKYVLPKFQMTIN SPQYILANVENVTWNICVKYSYGKPVKGNLLLKLTPQTPSWTRLPNLPAIRYETKLDKGDGCTDFVLSGSVLGLAHWKMD PNNIVLIAEFTEAGTGIVETTISRTVVLHEALKLEYEHYTPKYFKFGLPYHGKLRVLRYDDTPAPNEKIQICLKVRGKIE WEKDVVDCRDFRSSTDGFVDFVVPPQHKNIVLLSFVATAVDYPTTYYSPEQRWRVFMNQPSTSITVNPWYSPSDSYLTVA RGNQPIVCGEKYSFNVMYTTSSNMNETISFHYSINSKGSILIYGHVKHKPNRDTILNYFEFHNLLGTIESSANKTNKEAI VHRFPLSVKVTPSMAPVSELLLYYVRSDGEIVATTYTIEVGHCFENKVKSTWHTDAQIPGSPTQYHVEAAPRSLCAISAV DKSTLFLSKSESNLMSSTQTFDALKRFHPTPKFYFPWENSRCKSAIGPEEMKEEINHLPQFLRSKRQTITYSKRVNYVDA VQAFVDFGVIVMSDLVLETRPCPWLFMEYTALSRQYISTNEYMSMKDNSEFAVAAAAMDSGIGYVDQNQAQMATLRSYFP ETWLWELVPIGEEGKITIERTLPHTITDWVGYTTCISPTHGLGIAPPTTITAFQSFFLDYNLPYSIKRGEIMRFKVSLFN YMHHSLPVKIKLEEMEKIDLHLSEPTASFCVKPRDNIVHEYILKPRVIGEVNITVTAFVDIDYPEPCGSETVIFTQDVIV KPILILPEGFPVEETKSALICPKDSSDDSSFMWELTLPKDAVPDSGRAYLNLIGDILGPALENLDKLIKLPKGCGEQNMI LFVPNNHVIKYLDAMRINKPDLRAKAIRNMEKGYQRELKYRFMDGSYSAFEEGESSIWLTAFVLKSFAQAASLIHIDKYV LESSVSWITMNQLEDGCFPVIGTVFHKSMKGGLQEHGSSSALTAYILISLLESGVPLSPSVVNDAQKCLEKGMNNDDLYT TVLTTYVLALLEHPKANSSMKSLMNRATRYKNLIWWEDKSKPSIGLSIEMTAYVILTLLKLGEENLSEALKAVRWISKQR NSEGGFTSTQDTILGLEALTKYAMIVHHNNITDLSVLVTASKEVDDVYKLQDENRVILKQIRLPILPTIVEIFAQGEGCV LIQSNLKYNVASSTGSDAFDLSAEVRSVGYGNECSLQEITICSRYKMADEESNMALLEVGIISGYVPDRASLHSLLDPSS KVKLFEEDQDIVTIYFNKLTGQKTCISFRIIQEYFIDHLKPANIKLYDYYQQELTVSTNYKIPSICSSAEPVDEQLTTPN EMIIMKQLSFDESPMNSSFVVNNAELAIPDGMEGPIPVYVKLNTYDYKTEAATTTNGLPDLTSTFVTEDQTVPTVQTEDE EPIRIDTDNPSITNPLMKEVLRIVKILKINETNVPSPTRINQSCPICMDVLPSNISDIYCSANSAVKVAIRRFRKVRLLL DLHISREVKRLRAMIEFTLSPNCSCSPLDNPGSFALIINKDNDFLTSGNQKQTLNDSFYIYGLPLVSGVPCKLAEIRASC LNEDNIQCTYEDPPAYG >NP_033908.2 complement C3 preproprotein [Mus musculus] MGPASGSQLLVLLLLLASSPLALGIPMYSIITPNVLRLESEETIVLEAHDAQGDIPVTVTVQDFLKRQVL TSEKTVLTGASGHLRSVSIKIPASKEFNSDKEGHKYVTVVANFGETVVEKAVMVSFQSGYLFIQTDKTIY TPGSTVLYRIFTVDNNLLPVGKTVVILIETPDGIPVKRDILSSNNQHGILPLSWNIPELVNMGQWKIRAF YEHAPKQIFSAEFEVKEYVLPSFEVRVEPTETFYYIDDPNGLEVSIIAKFLYGKNVDGTAFVIFGVQDGD KKISLAHSLTRVVIEDGVGDAVLTRKVLMEGVRPSNADALVGKSLYVSVTVILHSGSDMVEAERSGIPIV TSPYQIHFTKTPKFFKPAMPFDLMVFVTNPDGSPASKVLVVTQGSNAKALTQDDGVAKLSINTPNSRQPL TITVRTKKDTLPESRQATKTMEAHPYSTMHNSNNYLHLSVSRMELKPGDNLNVNFHLRTDPGHEAKIRYY TYLVMNKGKLLKAGRQVREPGQDLVVLSLPITPEFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCI GTLVVKGDPRDNHLAPGQQTTLRIEGNQGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGS GKNYAGVFMDAGLAFKTSQGLQTEQRADLECTKPAARRRRSVQLMERRMDKAGQYTDKGLRKCCEDGMRD IPMRYSCQRRARLITQGENCIKAFIDCCNHITKLREQHRRDHVLGLARSELEEDIIPEEDIISRSHFPQS WLWTIEELKEPEKNGISTKVMNIFLKDSITTWEILAVSLSDKKGICVADPYEIRVMQDFFIDLRLPYSVV RNEQVEIRAVLFNYREQEELKVRVELLHNPAFCSMATAKNRYFQTIKIPPKSSVAVPYVIVPLKIGQQEV EVKAAVFNHFISDGVKKTLKVVPEGMRINKTVAIHTLDPEKLGQGGVQKVDVPAADLSDQVPDTDSETRI ILQGSPVVQMAEDAVDGERLKHLIVTPAGCGEQNMIGMTPTVIAVHYLDQTEQWEKFGIEKRQEALELIK KGYTQQLAFKQPSSAYAAFNNRPPSTWLTAYVVKVFSLAANLIAIDSHVLCGAVKWLILEKQKPDGVFQE DGPVIHQEMIGGFRNAKEADVSLTAFVLIALQEARDICEGQVNSLPGSINKAGEYIEASYMNLQRPYTVA IAGYALALMNKLEEPYLGKFLNTAKDRNRWEEPDQQLYNVEATSYALLALLLLKDFDSVPPVVRWLNEQR YYGGGYGSTQATFMVFQALAQYQTDVPDHKDLNMDVSFHLPSRSSATTFRLLWENGNLLRSEETKQNEAF SLTAKGKGRGTLSVVAVYHAKLKSKVTCKKFDLRVSIRPAPETAKKPEEAKNTMFLEICTKYLGDVDATM SILDISMMTGFAPDTKDLELLASGVDRYISKYEMNKAFSNKNTLIIYLEKISHTEEDCLTFKVHQYFNVG LIQPGSVKVYSYYNLEESCTRFYHPEKDDGMLSKLCHSEMCRCAEENCFMQQSQEKINLNVRLDKACEPG VDYVYKTELTNIELLDDFDEYTMTIQQVIKSGSDEVQAGQQRKFISHIKCRNALKLQKGKKYLMWGLSSD LWGEKPNTSYIIGKDTWVEHWPEAEECQDQKYQKQCEELGAFTESMVVYGCPN >NP_058690.2 complement C3 precursor [Rattus norvegicus] MGPTSGSQLLVLLLLLASSLLALGSPMYSIITPNVLRLESEETFILEAHDAQGDVPVTVTVQDFLKKQVL TSEKTVLTGATGHLNRVSIKIPASKEFNADKGHKYVTVVANFGATVVEKAVLVSFQSGYLFIQTDKTIYT PGSTVFYRIFTVDNNLLPVGKTVVIVIETPDGVPIKRDILSSHNQYGILPLSWNIPELVNMGQWKIRAFY EHAPKQTFSAEFEVKEYVLPSFEVLVEPTEKFYYIDDPKGLEVSITARFLYGKNVDGTAFVIFGVQDEDK KISLAQSLTRVLIEDGSGEAVLSRKVLMDGVRPSSPEALVGKSLYVSVTVILHSGSDMVEAERSGIPIVT SPYQIHFTKTPKFFKPAMPFDLMVFVTNPDGSPARRVPVVTQGSDAQALTQDDGVAKLSVNTPNNRQPLT ITVRTKKEGIPDARQATRTMQAQPYSTMHNSNNYLHLSVSRVELKPGDNLNVNFHLRTDAGQEAKIRYYT YLVMNKGKLLKAGRQVREPGQDLVVLSLPITPEFIPSFRLVAYYTLIGANGQREVVADSVWVDVKDSCVG TLVVKGDPRDNRQPAPGHQTTLRIEGNQGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGS GKNYAGVFMDAGLTFKTNQGLQTDQREDPECAKPAARRRRSVQLMERRMDKAGQYTDKGLRKCCEDGMRD IPMKYSCQRRARLITQGESCLKAFMDCCNYITKLREQHRRDHVLGLARSDVDEDIIPEEDIISRSHFPES WLWTIEELKEPEKNGISTKVMNIFLKDSITTWEILAVSLSDKKGICVADPYEITVMQDFFIDLRLPYSVV RNEQVEIRAVLFNYREQEKLKVRVELLHNPAFCSMATAKKRYYQTIEIPPKSSVAVPYVIVPLKIGLQEV EVKAAVFNHFISDGVKKILKVVPEGMRVNKTVAVRTLDPEHLGQGGVQREDVPAADLSDQVPDTDSETRI LLQGTPVAQMAEDAVDGERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDQTEQWEKFGLEKRQEALELIK KGYTQQLAFKQPSSAYAAFNNRPPSTWLTAYVVKVFSLAANLIAIDSQVLCGAVKWLILEKQKPDGVFQE DGPVIHQEMIGGFRNTKEADVSLTAFVLIALQEARDICEGQVNSLPGSINKAGEYLEASYLNLQRPYTVA IAGYALALMNKLEEPYLTKFLNTAKDRNRWEEPGQQLYNVEATSYALLALLLLKDFDSVPPVVRWLNEQR YYGGGYGSTQATFMVFQALAQYQTDVPDHKDLNMDVSLHLPSRSSPTVFRLLWESGSLLRSEETKQNEGF SLTAKGKGQGTLSVVTVYHAKVKGKATCKKFDLRVTIKPAPETAKKPQDAKSSMILDICTRYLGDVDATM SILDISMMTGFIPDTNDLELLSSGVDRYISKYEMDKAFSNKNTLIIYLEKISHSEEDCLSFKVHQFFNVG LIQPGSVKVYSYYNLEESCTRFYHPEKDDGMLSKLCHNEMCRCAEENCFMHQSQDQVSLNERLDKACEPG VDYVYKTKLTTIELSDDFDEYIMTIEQVIKSGSDEVQAGQERRFISHVKCRNALKLQKGKQYLMWGLSSD LWGEKPNTSYIIGKDTWVEHWPEAEECQDQKNQKQCEDLGAFTETMVVFGCPN >NP_001035559.2 complement C3 preproprotein [Bos taurus] MKPTSGPSLLLLLLASLPMALGNPMYSMITPNILRLESEETVVLEAHGGQGTIQVSVTVHDFPAKKQVLS NENTQLNSNNGYLSTVTIKIPASKELKSDKGHKFVTVVATFGNVQVEKVVLISLQSGYLFIQTDKTIYTP GSTVLYRVFTVDHKLLPVGQTVFITIETPDGIPVKRDSKSSQNQFGILTLSWNIPELVNMGVWKIKAYYE DSPQQVFSAEFEVKEYVLPSFEVQLEPEEKFYYIDDPDGLKVNIIARFLYGEQVDGTAFVIFGVQDGDRR ISLTHSLTRVPINDGNGEAILKRQVLLNGVQPSRADALVGKSIYVSATVILQSGSDMVEAERTGIPIVTS PYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTQGSNVQSLTQDDGVAKLSINTQNKRDPLTI TVRTKKDNIPEGRQATRTMQALPYNTQGNSNNYLHLSVPRVELKPGETLNVNFHLRTDPGEQAKIRYYTY MIMNKGKLLKVGRQYREPGQDLVVLPLTITSDFIPSFRLVAYNTLINAKGQREVVADSVWVDVKDSCMGT LVVKNGGKEEKHHRPGQQITLKIEADQGARVGLVAVDKGVFVLNKKNKLTQRKIWDVVEKADIGCTPGSG RNYAGVFTDAGLTLKTSQGLETQQRADPQCPQPATRRRRSVQLMEKRMDKAGQYSSDLRKCCEDGMRDNP MKFPCQRRAQFILQGDACVKAFLDCCEYITQLRQQHSRDGALELARIDLDDDIIPEEDIISRSQFPESWL WTVIEDLKQADKNGISTKLMNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVR NEQVEIRAILYNYREAENLKVRVELLYNPAFCSLATAKKRHQQTITIPARSSVAVPYVIVPLKIGLHEVE VKAAVYNHFISDGVKKTLKVVPEGVRVNKTVAVRTLNPEHLGQGGVQREEVPAADLSDQVPDTESETKIL LQGTPVAQMTEDAIDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTDQWEKFGLEKRQESLELIRK GYTQQLAFRQKSSAYAAFQYRPPSTWLTAYVVKVFALAANLIAIDSKDLCETVKWLILEKQKPDGIFQED GPVIHQEMIGGFRDTREKDVSLTAFVLIALHEAKDICEAQVNSLGRSIAKAGDFLENHYRELRRPYTVAI AAYALALLGKLEGDRLTKFLNTAKEKNRWEEPNQKLYNVEATSYALLALLARKDYDTTPPVVRWLNEQRY YGGGYGSTQATFMVFQALAQYQKDVPDHKELNLDVSIQLPSRNSAVRHRILWESASLLRSEETKENERFT VKAEGKGQGTLSVVTVYHAKLKGKVSCKKFDLRVSIRPAPETVKKPQDAKGSMILDICTKYLGDQDATMS ILDISMMTGFSPDVEDLKTLSTGVDRYISKYEMNRDSNKNTLIIYLDKVSHTVEDCLSFKVHQYFNVGLI QPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCRCAEENCFMHHTEKEVTLEDRLDKACEPGVD YVYKTRLIQKKLEDDFDEYIMVIENIIKSGSDEVQVKQERKFISHIKCREALKLKEGAHYLVWGVSSDLW GEKPKISYIIGKDTWVELWPEAEECQDEENQKQCEDLANFTENMVVFGCPN >NP_990736.3 complement C3 [Gallus gallus] MGCCCCPSCSAFCCSMRSPPAQMVTMVTPAVLRLDTDEKVVLEAPGLSAPTEANILVQDFPQKRKVLFQV RKQLNPAEGMMAIATVKVPVKLLPPVVGKHFVSVVARVGQVTLEKVLLVSLQSGHIFLQTDKPIYTPGST VLCRLFALSHFMQPLLKTVIVEVKTPDNVIIKQVPVSSPMRNGIFSINHNLPEVVSLGTWTITAKFEDSQ DQVFSTQFEVKEYVLPSFEVTLDPQEKFLYIDRQEDFRVTITARYLYGKNLQGTAFVLFGVVVDDEKKTI PQSLQRVKVTDGDGEAVLPMAMLRQRFANLQELVGHSLYVTVTVLTESGSDMVEAQRSGIRIVTSPYTIH FTHTPKYFKPGMPFDLTVYVTNPDNSPAPRIPVKADNFQGLVSTQRDGTAKLVLNMPANKNSVPITVRTD QKDLPPERQASRQIVAEAYQSQGNSGNYLHLAVGASQVQPGDNLPINFHLKSNRDDVRKSVSYFTYLILS KGHIVHVGRQPREGDQSLVTMSLPVTANLIPSFRIVAYYHVKPGEIIADSVWVDVKDTCMGSLVVRGASE ADNRVHEPRTPMRLHIEGDHKAHVGLVAVDKAVYVLNKNKLTQSKVWDTVENSDIGCTPGSGRNHVGVFA DAGLSLTSNVNINTEQRSEVQCAKPAKRKRRSVRLIKHKGTKMAEYSDKNLRKCCEDGMKENLMGYSCEK RATYVLDGKACTEAFLSCCLYIKGIRDEERELQYELARSEVDDAFLSDEDITSRSLFPESWLWQVEELTE PPNEQGISMKTLPIYLKDSITTWEVLAVSISENKGLCVADPYEITVMKEFFIDLRLPYSAVRNEQVEVRA ILYNYWTNKIKVRVELMYNPALCSASTTKTRYQQIFQLEPQSSHAVPFVIVPLQLGQHDVEVKAAVWNSF VSDGVKKKLRVVPEGMRLEKTVKIVELDPKTLGNNGVQEVKVKAANLSDIVPNTESETKVSIQGNPVSIL VEKATDGTKLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDSTMQWETFGINRRTEAIELIKKGYTQQLAYR KEDGSFAAFTTRPSSTWLTAYVAKVFAMAINMVDIKPEVVCGAIKWLILEKQQPDGLFQEDAPVIHKEMV GGYHGAEPSVSLTAFVLSALQESQKICKNYVKSLDGSIAKASDYLSRKYQSLTRPYTVALTSYALALTGK LNSEKVLMKFSKDGTHWAERNAHTYNIEGTSYALLALLQMEKAELTGPVVRWLAQQNYFGGGYGSTQATI LVFQALAQYHVALPRQLELNLDVSVLLPRRANAITYRIENNNALVARSAETKLNEDFTVKAEGTGKGTMT VVTVYNAKVPEKENKCDNFDLRVSVEDVKAGRELEGVIRSVKITICTRFLDTVDATMSILDISMLTGFSP DVQDLKSLSEGVERYISKFEIDHALSNRSNLIIYLDKVSHQVEECIAFRAHQHFQVGLIQPASVTVYSYY KIDDRCTRFYHPDKAGGQLRKICHGEVCRCAEENCFIRVKKDNPITVNERIDLACKPGVDYVYKVKVVAT EETPSHDNYIMSILTVIKMGTDENPGGSNRTFVSHKQCRDALSLQKGQDYLVWGLASDLWVTGSRFSYLI SKDTWLEAWPLEESCQDADLQPLCQDFTEFSDNMVLFGCPT >XP_020936478.1 complement C3 isoform X1 [Sus scrofa] MGSTSGPRLLLLLLTSLPLALGDPIYTIITPNVLRLESEEMVVLEAHEGQGDIRVSVTVHDFPAKRQVLS SETTTLNNANNYLSTVNIKIPASKEFKSEKGHKFVTVQALFGNVQVEKVVLVSLQSGYLFIQTDKTIYTP GSTVLYRIFTVDHKLLPVGQTIVVTIETPEGIDIKRDSLSSHNQFGILALSWNIPELVNMGQWKIRAHYE DAPQQVFSAEFEVKEYVLPSFEVQVEPSEKFYYIDDPNGLTVNIIARFLYGESVDGTAFVIFGVQDGDQR ISLSQSLTRVPIIDGTGEATLSQGVLLNGVHYSSVNDLVGKSIYVSVTVILNSGSDMVEAERTGIPIVTS PYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTEDFKVRSLTQEDGVAKLSINTPDNRNSLPI TVRTEKDGIPAARQATKTMHVLPYNTQGNSKNYLHLSVPRVELKPGENLNVNFHLRTDPGYQDKIRYFTY LIMNKGKLLKVGRQPRESGQVVVVLPLTITTDFIPSFRLVAYYTLIAANGQREVVADSVWVDVKDSCVGT LVVKGGGKQDKQHRPGQQMTLEIQGDRGARVGLVAVDKGVFVLNKKNKLTQRKIWDVVEKADIGCTPGSG KDFAGVFTDAGLAFKSSKGLQTPQRADLECPKPAARKRRSVQLMEKRMDKLGQYSKELRRCCEHGMRDNP MKFSCQRRAQFIQHGDACVKAFLDCCEYIAKLRQQHSRNKPLGLARSDLDEEIIPEEDIISRSQFPESWL WTIEEFKEPDKNGISTKTMNVFLKDSITTWEILAVSLSDKKGICVADPYEVVVKQDFFIDLRLPYSVVRN EQVEIRAILYNYREAEDLKVRVELLYNPAFCSLATAKKRHQQTLTVPAKSSVPVPYIIVPLKTGLQEVEV KAAVYNHFISDGVKKTLKVVPEGMRVNKTVVTRTLDPEHKGQQGVQREEIPPADLSDQVPDTESETKILL QGTPVAQMVEDAIDGDRLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGLEKRQEALELIKKG YTQQLAFRQKNSAFAAFQDRLSSTWLTAYVVKVFAMAANLIAIDSQVLCGAVKWLILEKQKPDGVFEENG PVIHQEMIGGFKNTEEKDVSLTAFVLIALQEAKDICEPQVNSLLRSINKARDFLADYYLELKRPYTVAIA GYALALSDKLDEPFLNKLLSTAKERNRWEEPGQKLYNVEATSYALLALLVVKDFDSVPPIVRWLNEQRYY GGGYGSTQATFMVFQALAQYQKDVPDHKDLNLDVSIHLPSRSAPVRHRILWESASLLRSEETKENERFTL IAEGKGQGTLSVRNEDPYLLDSLPFLDSSAPEAPFPPQVKWADTLSPFPSHQVVTMYHAKTKGKTTCKKF DLKVSIHPAPEPVKKPQEAKSSMVLDICTRYLGNQDATMSILDISMMTGFSPDTEDLKLLSTGVDRYISK YELNKALSNKNTLIIYLDKISHTLEDCISFKVHQYFNVGLIQPGSVKVYSYYNLDESCTRFYHPEKEDGM LNKLCHKEMCRCAEENCFMHHDEEEVTLDDRLERACEPGVDYVYKTRLLKKELSDDFDDYIMVIEQIIKS GSDEVQVGQERRFISHIKCREALKLKEGGHYLVWGVSSDLWGEKPNISYIIGKDTWVELWPDGDVCQDEE NQKQCQDLANFSENMVVFGCPN >XP_038284790.1 complement C3 [Canis lupus familiaris] MGPASGPRLLLLLLLTSLPLALGDPMFSMITPNILRLENKETVVLEAHDLKENTEVTVTVHDFPAKKQVL FREKTDLTSANQYMSTVTIQMPANKDAKSEKGSKFVIVQAAFGATVLEKVVLVSFQSGYLFIQTDKTIYT PSSTVLYRVFTVDHNLLPIGRSVIISIQSPDGVTVKRGSLSSQNQDGILSQSWYIPELVNMGQWKIQAHY EDAPEQVFSAEFEVKEYVLPSFEVQVEPAQKFYYIDSTEGLDVTIMARFLYGKEVDGTAFVIFGVQDGDR RISLSQSLTRILIEDGNGVATLKRNVLLEGVRPSRPDALVGKSLYVSATVILHSGSDMVEAESNAIPIVT SPYQIHFTKTPKFFKPAMPFDLMVFVTNPDGSPAPHVPVGIQNYRVQALTQKDGVAKLTINTPDSKKPLH ITVSTKKEGILESRQATRTMEVQPYNTIGNSRNYLHLSVPRMELKPGETLNVNFHLRTDPSKEAQIRYYT YLIMNKGKILKVGRQERESGQDLVVLPLTITSDFIPSFRLVAYYTVIGSSGQREVVADSVWVDVKDSCMG TLVVKGSGKEQRSHLPGQQTTLIIQGDPGARVGLVAVDKGVFVLNKKNKLTQSKIWNVVEAADIGCTAGS GKDYAGVFMDAGLALKTNKELQTPQRRDLECPKPAARRRRSVVLTEKRMDKVGQYPKELRKCCEGGMRDN PMKFSCERRAQFVSREESESCVKAFLECCKYITQLRLNYSRMDNLGLARSDMDEELFLEEDIVSRSQFPE SWLWTIEILNEPEKNGISTKTMNVFLKDSITTWEILAVSLSKKKGICVADPYEVTVLQDFFIDLRLPYSV VRNEQVEIRAILYNYQEREDIKVRVELLYNPAFCSLATSKKSYQQIVNIPAKSSVAVSYVIVPLKIGLHE VEVKAAVYRHFANDGVKKILKVVPEGILVNQTLAIRTLDPEAKGQEGVQREEVHAADLGDQVPDTESETR ILLQGTPVAQMVEDAIDGDRLKHLIVTPSGCGEQNMIGMTPTVIALHYLDQTEQWDKFGLEKRQEALELI KKGYTQQLAFRQPNSAFAAFQNRPSSTWLTAYVVKVFSLATNLIAIEAQVLCGAVKWLILEKQKPDGIFQ EDGPVIHQEMTGGFREAEEKSVSLTAFVLIALKEAEDICIGQVNILPSSIEKAGNYLAAHYQNLRRPYSV AIAGYALAHLDKLEGDNLRKFLNTARDRNRWVEPGKKLYNVEATSYALLALLLLKDFDNVPPVVRWLNEQ RYYGGGYGSTQATFMVFQALAQYQKDVPNHKDLNLQVSINLPSRSTEIKHHIVWDSPSLQRSEETKKNEN FEVIAKGKGQGTLSVVTMYYAKLKNKATCKKFDLRVDIQPAPENVKRPQDALNSMTLNICTRYLGDEDAT MSILDISMMTGFSPDTCDLNQLSSGIERYISKYELNKAFSNKNNVILYLEKISHNQEDCISFRVHQYFKV GLIQPGSVKVYSYYNLDESCTRFYHPEKEDGQLSKLCHKDMCRCAEENCFMQQVYDKVTKDERLDKACEP GVDYVYKTRLLRKEPAEDFDEYVMAVEQIIKSGSDEVARGQERRFISHIRCREALKLQDGKRYLVWGVST DLWGEKPKINYIIGKDTWVEMWPEADECQDEENEKRCQDLASFTDDMITFGCPN >XP_008251121.2 PREDICTED: complement C3 alpha chain isoform X1 [Oryctolagus cuniculus] MNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEVRAVLYNYRESDSL KVRVELLYNPAFCSLATAKKNHQQTVTIPPKSSLPIPYVLVPLKIGLQEVEVKAAVYNRFISDGVKKTLK VVPEGMPINKTVAVRTLDPENLGQGGVQKEEIPPADISDQVPGTESETKILLQGTPVAQMTEDAIDGERL KHLIVTPSGCGEQNMIAMTPTVIAVHYLDHTEQWDKFSLEKRQEALELIKKGYTQQLAFKQPNSAYAAFL NRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLIMEKQKPDGVFQEDAPVIHQEMIGGQRNSVEKE AALTAFVLIALQEAREICEEQVNSLAASINKSRDFLAANYMNLQRPYSVAIAGYALAQQDKLRGAFLNKF LSKAKEKNRWEEPGQRLYNVEATSYALLALLLLRDFDSVPPVVRWLNEQRYYGGGYGSTQATFMVFQALA QYQTDVPDHKDLNMVVSIQLPSRSSPVKHRIVWDSASLLRSEETKENQGFTLTAQGKGQGTLSVVTTYFA KVKGKVTCKKFDLRVNIRPAPETVKKPQDAKSTMILDICTRYLGDEDATMSILDISMMTGFVPDTDDLNL LSTGVDRYISKYELNKAFSNKNTLIIYLDKISHSREECLSFKVHQYFNVGLIQPGAVKVYSYYNLEETCT QFYHPEKEDGMLSKLCHKEMCRCAEENCFMQQLDEKVTLNDRLDKACEPGVDYVYKTKLVQVERADDFDE YLMVVENTIKSGSDEVQAGQQRRFISHIKCRDALKLKDGKHYLVWGLSSDLWGEKPNTSYIIGKDTWVEF WPEKEECQDEENQKHCEDLDAFAESMVVFGCPN >XP_024092530.1 complement C3 isoform X1 [Pongo abelii] MGPTSGLSLLLLLLTHLPLALGSPMYSIITPNILRLESEETVVLEAHGVQGDVPVTVTVHDFPGKKLVLS SEKTVLTPATSHMGNVTFTIPANREFKSEKGRNKFVTVQATFGPQVVEKVVLVSLQSGYLFIQTDKTIYT PGSTVLYRIFTVNHKLLPVGRTVMVNIENPDGVPVKQDSLSSQNQFGILPLSWDIPELVNMGQWKIQAYY ENSPQQVFSAEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQ RISLPESLKRIPIEDGSGDAVLSRKVLLDGVQNPRAEDLVGKSLYVSVTVILHSGSDMVQAERSGIPIVT SPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDAVQSLTQGDGMAKLSINTHPSQKPL SITVRTKKQELSEAEQATRTMQAQPYSTVGNSNNYLHLSVPRTELRPGETLNVNFLLRMDRAHEAKIGYY TYLIMNKGKLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCV GSLVVKSGQTEDRQPVPGQQMTLKIEGDHGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPG SGKDYAGVFSDAGLTFTSSTGQQTAQRAELQCPQPATRRRRSVQLTEKRMDKVGKYPKELRKCCEDGMRE NRMRFSCQRRTRFISLGEACKKAFLDCCNYMTELRRQHTRASHLGLARSNLDEDIIAEENIVSRSEFPES WLWNIEDLKEQPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVV RNEQVEIRAVLYNYRQNEELKVRVELLHNPAFCSLATTKRRHQQTVTIPAKSSLSVPYVIVPLKTGLQEV EVKAAVYHYFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRI LLQGTPVAQMTEDAIDAERLKHLIVTPSGCGEQNMISMTPTVIAVHYLDETEQWEKFGPEKRQGALELIK KGYTQQLAFRQPSSAYAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQE DAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVA IAGYALAQMDRLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQR YYGGGYGSTQATFMVFQALAQYQKDVPDHKELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGF TVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATM SILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVE LIQPGAVKVYAYYNLAESCTRFYHPEKEDGKLDKLCRDELCRCAEENCFIQKLDDKITLEERLDKACEPG VDYVYKTRLVKAQLSNDFDEYIMAIEQIIKSGSDEVQVGQQRTFISPIKCREALKLEERKHYLMWGLSSD FWGEKPNLSYIIGKDTWVEHWPEEDECQDEENQKQCQDLGTFTENMIVFGCPN >XP_010726629.1 complement C3 [Meleagris gallopavo] MGPLLLPLLLGVLLLHVVPTPAQMVTMVTPAVLRLVTDEQVVLEAPGLTSPTEANILVQDFPQKRKVLFQ IRKQLNPAEGMMATATIKVPVKLLPQVVGKHFVSVVARVGQVTLEKVLLVSLQSGHIFLQTDKPIYTPGS TVLCRLFALSRFMQPLLKTVIVEVKTPDNVIIKQVPVSSPKRNGIFSINHNLPEVVSLGTWTITAKFEDS QDQVFSTQFEVKEYVLPSFEVTLDPQEKFLYIDRQEDFRVFIKARYLYGKNLQGTAFALFGVMVDDERKT IPQTLQRVKVTDGDGEVVLPMAMLRQRFANLQELVGHSLYVTVTVLTESGSDMVEAQRSGIRIVTSPYTI HFTHTPKYFKPGMPFDLTVYVTNPDNSPAPRIPVKADNFQGLVSTQRDGKAKLVLNMPANKNSVPITVRT AQKDLPPERQASQQMVAEAYQSQGNSGNYLHLAVGASQVQPGDNLPVNFHLKSNREDVRRSVSYFTYLIL SKGHIVHVGRQPREGDQSLVTMSLPVTANLIPSFRIVAYYHVKPGEIVADSVWVDVKDTCMGNLVVKGAS EADNRVHEPRTPMRLRIEGDHKAHVGLVAVDKAVYVLNKNKLTQSQVWDTVEKSDIGCTPGSGRDHVGVF ADAGLSLATNVNIKTEQRGEVECAKPAKRKRRSVKLIKYKGTKMAEYNDRNLRKCCEDGMKENLMGYSCE KRATYILDGKACTDAFLNCCLYIKGIRDEERDLHYELARSEADDAFLADEDITSRSLFPESWLWQVEELT EPPNELGISTKTLPIYLKDSITTWEVLAVSLSEKKGLCVADPYEITVMKEFFIDLRLPYSAVRNEQVEVR AILYNYWKSKIKVRVELMYNPALCSASTSKTRYQQILQLEPQTSHAVPFVIVPLQLGQHDVEVKAAVWES FVSDGVKKKLRVVPEGMRLEKTVKIVELDPKTLGNNGVQEVKVKAANLSDIVPNTESETKVSIQGNPVSI LVEKAIDGTKLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDSTMQWETFGINRRAEAIELIKKGYTQQLAF RKDDGSFAAFTNRPSSTWLTAYVAKVFAMAINMVDIKPEVVCGAIKWLILEKQKPDGLFQEDAPVIHKEM VGGYHGAEPSVSLTAFVLTALQESQKICKNYVKSLDGSIAKASDYLSRKYQSLTRPYTVALSSYALALTR KLNSEKLLMKFSKDDTHWAERNAHTYNIEGTSYALLALLQMEKTELTGPVARWLAQQNYFGGGYGSTQAT ILVFQALAQYHVVLPRQMELNLDVSVLLPRRANAITYRIENSNALVARSAETKLNEDFTVKAEGTGKGTM TVVTVYNAKVPENENKCDNFDLRVSVEDVKTARDLEGAIRSVKITICTRFLDTVDATMSILDISMLTGFS PDVQDLKSLSEGVERYISKFEIDHSLSNRSNLIIYLDKISHQVEECIAFRAHQHFQVGLIQPASVSVYSY YKIDDRCTRFYHPDKDGGQLRKICHGDVCRCAEENCFTRQKKDNPITVNERIDLACKPGVDYVYKVKVVA TEETSSHDNYIVTILSVIKMGTDEDPLGSNRTFVSHKQCRDALSLQKGQDYLVWGLASDLWVTGSRFSYL IGKDTWLEAWPLEESCQDADLQQLCQDFIEFSEAMTMFGCPS >XP_017906433.1 PREDICTED: LOW QUALITY PROTEIN: complement C3 [Capra hircus] MQPTSGPSLLLLLLLASLPMALGNPMYSMITPNILRLESEETVVLEAHGGQGNIQVSVTVHDFPAKKQVL SNENTQLNSNNGYLSTVIIKIPASKELKSEKGHKFVIVVATFGNVQVEKVVLISLQSGYLFIQTDKTIYT PGSSVLYRVFTVDHKLLPVGQTVFISIETPDGVLVKQDSLSSHNQFGILALSWNIPELVNMGVWKIKAHY EDSPQQVFSTEFEVKEYVLPSFEVQLEPEEKFYYVDDPDGLKINIIARFLYGEQXDGTAFVIFGVQDGDR RISLTHSLTRVPINDGNGEAILKRQVLLNGVQPSRADALVGKSIYVSATVILQSGSDMVEAERTGIPIVT SPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTQGSNVQSLTQDDGVAKLSINTQNKRDPLT ITVRTKKDNIPEGRQATRTMQALPYNTQGNSNNYLHLSVPRVELKPGETLNVNFHLRTDPSQQAKIHYYT YMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLINANGQREVVADSVWVDVKDSCMG TLVVKNDGKEEKKHRPGKQITLKIEANHGSRVWLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGS GRDYAGVFTDAGLTFKTSQGLETQQRSDPQCPKPAARRRRSVQLMEKRMDKVGQYSGDLRKCCEDGMRDN PMKFPCQRRAQFILQGDACVKAFLDCCEYIARLRQQHSREGALELARSDLDDEIIPEEDIISRSQFPESW LWIIIDDFKQPDKNGISTKLTKVFLKDSITTWEILAVSLSDKKGICVADPYEITVMQDFFIDLRLPYSVV RNEQVEIRAILYNYREAENLKVRVELLYNPAFCSLATAKKRHQQNIMIPARSSVAVPYVIVPLKVGLHEV EVKAAVYNHFISDGVKKTLKVVPEGIRVNKTVAIRTLNPEYLGQDGVQREEVPAADLSDRVPDTESETKI LLQGTPVAEMAEDAIDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQEALELIR KGYTQQLAFRQKSSAYAAFQNRPPSTWLTAYVVKVFALSANLIAIDSRDLCETVKWLILEKQKPDGIFQE DGPVIHQEMIGGFKDAREKDVSLTAFVLIALHEAKDICEAQVNSLGRSITKAGNFLENHYRELRRPYTVA IAAYALALLGKLEDDRLTKFLNTAKEKNRWEEPNKKLYNVEATSYALLALLARKDFDTVPPVVRWLNEQR YYGGGYGSTQATFMVFQALAQYQKDVPDHKELNLDVSIHLPSRNSLVKHRILWESASLLRSEETKENEPF TVRAEGKGQGTLSVVTMYHAKLKGKVSCKKFDLRVSIHPTLEPVKKPQDAKGSMILDICTKYLGDQDATM SILDISMMTGFSPDIDDLKLLSTGVDRYISKYEMNRDSNKNTLIIYLDKVSHTQEDCLSFKVHQYFNVGL IQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCHCAEENCFMHHTEEAITLEDRLDRACEPGV DYVYKTRLLQKKLEEDFDEYIMVIEQIIKSGSDEVQVKQERKFISHIKCREALKLKEGAHYLVWGVSSDL WGDKPNISYIIGKDTWVELWPEAEECQDEENQKQCEDLASFTENMVVFGCPN >XP_034802768.1 complement C3 [Pan paniscus] MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETVVLEAHDAQGDVPVTVIVHDFPGKKLVLS SEKTVLTPATNHMGNVTFMIPANREFKSEKGRNKFVTVQATFGAQVVEKVVLVSLQSGYLFIQTDKTIYT PGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQFGILPLSWDIPELVNMGQWKIQAYY ENSPQEVFSAEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQ RISLPESLKRILIEDGSGEVVLSRKVLLEGVQNPRAEDLVGKSLYVSVTVILHSGSDMVQAERSGIPIVT SPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPL SITVRTKKQELSEAEQATSTMQALPYSTVGNSNNYLHLSVPRTELRPGETLNVNFLLRMDRAHEAKIRYY TYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCV GSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPG SGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVLLTEKRMDKVGKYPKELRKCCEDGMRE NPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARAGHLGLARSDLDEDIIAEENIVSRSEFPES WLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVV RNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEV EVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRI LLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIK KGYTQQLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQE DAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVA IAGYALAQMGRLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQR YYGGGYGSTQATFMVFQALAQYQKDVPDHKELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGF TVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATM SILDISMMTGFAPDTDDLKQLASGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVE LIQPGAVKVYAYYNLAESCTRFYHPEKEDGKLNKLCRDELCRCAEENCFIQKSDDKVTLEERLDKACEPG VDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGSDEVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSD FWGEKPNLSYIIGKDTWVEHWPEEDECQDEENQQQCQDLGAFTESMVVFGCPN >XP_018871079.1 complement C3 [Gorilla gorilla gorilla] MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETVVLEAHDAQGDVPVIVTVHDFPGKKLVLS SEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGAQVVEKVVLVSLQSGYLFIQTDKTIYT PGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQFGILPLSWDIPELVNMGQWKIRAYY ENSPQQVFSAEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQ RISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNPRAEDLVGKSLYVSVTVILHSGSDMVQAERSGIPIVT SPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGKDTVQSLTQGDGVAKLSINTHPSQKPL SITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVPRTELRPGETLNVNFLLRMDRAHEAKIRYY TYLIMNKGRLLKAGRQMREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCV GSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPG SGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVQLTEKRMDKVGKYPKELRKCCEDGMRE NPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVSRSEFPES WLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVV RNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEV EVKAAVYHHFISDGVRKSLKVVPEGFRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRI LLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQAALELIK KGYTQQLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQE DAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVA IAGYALAQMGRLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQR YYGGGYGSTQATFMVFQALAQYQKDVPDHKELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGF TVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATM SILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVE LIQPGAVKVYAYYNLAESCTRFYHPEKEDGKLNKLCRDELCRCAEENCFIQKSDDKVTLEERLDKACEPG VDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGSDEVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSD FWGEKPNLSYIIGKDTWVEHWPEEEECQDEENQKQCQDLGAFTESMVVFGCPN >XP_021136840.1 complement C3 [Columba livia] MEMRSRWSHFWVTMVAPAVLRLDTEEQVVLEAPGLTVATEATLLVQDFPGKRQVLYQVRVPINPAQGMLA TATIKVSAKALPPAQGKRFVSVTARVAQVTLEKVLLVSLQSGHIFVQTDKPIYTPSSTVLCRLFALDHRM EPAPKTVVVEFKTPDNIIVKQVPVSSPMKTGIFSLNHYLPEVVSLGTWTIMAKFEDSPEQVFSTQFEVKE YVLPSFEVLLEPEEKFLYIDRQEDFRVTVTARYLYGKHLQGSAFVLFGVMVDDEKKSIPQSLQRIQVTDG DGEAILSMADLRQRFKNPQELVGHSLYVSVTVLTDSGSDMVETQRSGIHIVTSPYTIHFTHTPKYFKPGM PFDLTVYVTNPDGSPAPRVTVKADGFQGIVSTQRDGTAKLVLNMPANKDTVPITVRTDQPGLPAERQASR QMTAEAYRSQGSSGNFLHLAVGATEVKPGDNLVVNFHLKSSSNAVRDAVRFFTYLIMSKGRIVRVGRQAH EAGQSLVTMSLPVTAELIPSFRIVAYYYVMPSEIVADSVWVDVKDTCMGSLVVKGASEADNRVHEPGTPM RLRIEGDHKAHVGLVAVDKGVFVLNKKHKITQAKVWDTVEKSDIGCTAGSGRDNVGVFADAGLSIVTSEK VTTPQRAEVQCPQPAKRKRRSLQLMEYKGTKAAEYTDKAQRKCCEDGMKDNPMGHSCERRATYIQDGETC VQAFLTCCNYIKGIREQKQRELHLQLARSEVDDGFLDDDDIPSRSLFPESWLWQEETLTEPPNDLGISGK TLPIYLKDSITTWEVLAVSLSPTKGLCVADPYEITVMKEFFIDLRLPYSVVRNEQVEIRAVLYNYWTHEI TVRVELVHNPAICSASTSKTRYQQILKLKPQSSWAVPFVIVPLQLGQHDVEVKAAVRGSFVADGVKKKLK VVPEGIRLEKTVKIVELDPKTKGINGVQEERVRAANLSDIVPNTESETKVSIQGNPVSILVEKAIDGDKL KHLIVTPAGCGEQNMIGMTPTVIATHYLDSTQQWESFGIDRRAEAINLIKKGYTQQLAFRKPDNSYAAFK DRPSSTWLTAYVAKVFSLAITLVDIEPEVVCGAVKWLILEKQKPDGIFQEDAPVIHKEMVGGYQGAEPEV SLTAFVLIALQESREICKDRVNSLERSITKAAQYLTKRYQSLARPYTVALTSYALALTGHLKSEKVLMKF SKGGKSWEERNARTYNMEGTSYALLALLQMEKAELTGPVARWLAQQNYFGGGYGSTQATMLVFQALAQYQ LASPRQLELNLDVSLLLPRRAKPVTYRIENRNALVARSAETKLNEDFTVKAEGTGKGTMTVVTVYNAKVP EKDNKCDNFDLRVQVEDVKAGKEEDGVVRSVKITICTRHLDNVDATMSILDVSMLTGFSPDLQDLKRLTE GVDRYISKFEIDKALAERSNLVIYLDKISHKAEECFAFKAHQRFRVGLIQPAAVTVYSYYKIDDRCTRFY HPDKDGGQLSKICYGDICRCAEENCFVRHKDDVAVTVNQRIERACEAGVDYVYKVKLVATEQSPSHDNYI MTVLSVIKTGTDEDPAGGNRTFVSHRQCRDALQLRLGQEYLVWGLASDMWVTNGRFSYLVGKDTWLELWP SEDACQEPDLMSLCQDLLDFAEAMTMFGCPS >XP_006023407.1 complement C3 [Alligator sinensis] MEGSICYLAAVLLFCFPAVVHSQLYSLIIPNVLRVESEEKVVVEANGLSAVTEVTITVHDFPFKRQVLYL IKANLNPDEGMLTTATIKISSNQVKKDSRDNQYVLIQAKIKDVTLEKVVLLSFHSGYIFVQTDKTIYTPG STVLCRIFAMGHKMEPLFKTVIVEFETPEGIIVKQSPVFSPMKTGIYSLNYNLPEIVNLGTWKVVAKFQD SPLQNFSTQFEVKEYVLPSFEVILEPSEKFLYIDDDKDFRVSITARYLYGKKLEGTAFVLFGVKMENEKR SIPQSLKRIQIQDGDGEAVLTRGMLQARFPNLQELVGHTLYISVTVLTESGSDMVEAERTGIHIVTSPYQ IHFTKTPKYFKPGMPFELMVYVTNPDGSPAPRVPVKADNFQGTVSTQGNGMAKLILNMPGDKERVKVTVR TVHENLKPENRQASQSMVAEAYKTQGGTKNYLHLAVTASELKSGDNLPVNFHLKTDNINILNGLKHFSYL ILNKGKIVQAGRQLRQAGQNLVSMPLPITPDLVPSFRIVAYYQVGSSEMVADSVWVDVKDTCMGTLVVKG ATEADNRIHEPGTPMKIKVEGDYKAHVGLVAVDKGVYVLNKKFKFTQSKIWDTVEKSDIGCTAGGGRDNL GVFADAGLALQTNTISTPQRTEFDCPQPASRKRRSVQLIEHKASKVANYHDQKLKKCCEDGMYENPMGHS CDKRAVYIQDTKECVAAFLDCCKYIKTIRDEKQRELVLELARSEVDEGFLSDDDITSRSLFPESWLWQVE QLTEQPNNMGISTKTIPVFLKDSITTWEVLAVSLSENKGICVANPYEITVMKDFFIDLRLPYSVVRNEQV EIRAILYNYWDKNIKVRVELIHNPAFCSASTSKQRYRQIYDLPRLSSLAVPLVIVPLELGLHDVEVKAAV WGQFVADGVKKKLKVVPEGMRMTKTVKSVTLEPSVKGLGGVQVEQVTAADIEDIVPNTESETRVSVQGNP VTTIIEKSIDGANVKHLIVTPSGCGEQNMIGMTPTVIATHYLDSTNQWDKVGVDRRNEAIRLINQGYTQQ LVYKKGDFSYSAFQNRESSTWLTAYVAKVFAMATSLVGIEHQVLCGAVKWLILEKQKPDGVFQEDGPVIH GEMVGGYKGAEPEVSLTAFVLIALHESKDICKDHINSLEGSINKAAEFLSKKYMFLKRPYTIALTSYALA LVEKLNSEKVLMKCAKGANHWEEKGARTFNIEGTSYGLLALLKMKKFELTGPIVRWLTEQKYYGGGYGST QATILVFQALSQYQMDIPQQSELQLDVSILLPRRATPVKIRIENSNAFLSRSAETKWNENFTVRAEGTGQ GTLTVVTVYNAKIKEDESKCKKFYLSVSVENIPRPKNKEGILRSVKINICTRFLGEVDATMSIIDVSMLT GFSPDTDDLKRLSQGVDRYISKFEMDKAPSERASLIIYLDKVSHTEEECLSFKAHQFFEVGLIQPASVTV YDYYTIDDRCTKFYHPSKQSGLLSKICHGDVCRCAEENCFMQHKMDSPVTLDKRIEDACEPGVDYVYKTR LVETEESSSYDNYIMEILTIIKAGTDENPVGQRRKFISHVKCRESLNLEQNKDYLIWGLSSDLWTMKNEL SYIISKDTWIEKWPNEEECQEPDFQKLCQEFQEFSEAMTMFGCPT >XP_006265663.2 PREDICTED: complement C3 [Alligator mississippiensis] MEGSICYLAAVLLFCFPAVVHSQLYSLITPNVLRVESEEKVVVEANGLNAATEVTITVHDFPFKRQVLYL IKANLNPDEGMLTTATIKISSNQVKKDSRDNQYVLIQAKIKDVTLEKVVLLSFHSGYIFVQTDKTIYTPG STVLCRIFAMGHKMEPLFKTVIVEFETPEGIIVKQSPVFSPMKTGIYSLNYNLPEIVNLGTWKVVAKFQD SPLQNFSTQFEVKEYVLPSFEVILEPSEKFLYIDDVKDFRVSITARYLYGKKLEGTAFVLFGVKMENEKR SIPQSLKRIQIQDGDGEAVLTRGMLQARFPNLQELVGHTLYISVTVLTESGSDMVEAERTGIHIVTSPYQ IHFTKTPKYFKPGMPFELMVYVTNPDGSPAPRVPVKADDFQGTVSTQGNGMAKLILNMPGDKERVKVTVR TVHENLKPENRQASQSMVAEAYKTQGGTKNYLHLAVTASELKSGDNLPVNFHLKTDNINILNGLKHFSYL ILNKGKIVQAGRQLRQAGQNLVSMPLPITPDLVPSFRIVAYYQVGSSEIVADSVWVDVKDTCMGTLVVKG ATEADNRIHEPGTPMKIKVEGDYKAHVGLVAVDKGVYVLNKKFKFTQSKIWDTVEKSDIGCTAGGGRDNL GVFVDAGLALQTNTISTPQRTEFDCPQPASRKRRSVQLIEHKASKVANYHDQKLKKCCEDGMYENPMGHS CDKRAMYIQDTKECVAAFLDCCKYIKTIRDEKQRELVLELARSEVDEGFLSDDDITSRSLFPESWLWQVE QLTEQPNNMGISTKTIPVFLKDSITTWEVLAVSLSENKGICVADPYEITVMKDFFIDLRLPYSVVRNEQV EIRAILYNYWDKNIKVRVELIHNPAFCSASTSKQRYRQIYDLPRLSSLAVPLVIVPLELGLHDVEVKAAV WGQFVADGVKKKLKVVPEGMRMTKTVKSVTLEPSVKGLGGVQVEQVTAADIEDIVPNTESETRVSVQGNP VTTIIEKSIDGANVKHLIVTPSGCGEQNMIGMTPTVIATHYLDSTNQWDKVGVDRRNEAIRLINQGYTQQ LVYKKGDFSYSAFQNRESSTWLTAYVAKVFAMATSLVGIEHQVLCGAVKWLILEKQKPDGVFQEDGPVIH GEMVGGYKGAEPEVSLTAFVLIALHESKDICKDHINSLEGSINKAAEFLSKKYMFLKRPYTIALTSYALA LVEKLNSEKVLMKCAKGANHWEEKGARTFNIEGTSYGLLALLKMKKFELTGPIVRWLTVQKYYGGGYGST QATILVFQALAQYQMDIPQQSELQLDVSILLPRRATPVKIRIENSNAFLSRSAETKWNENFTVRAEGTGQ GTLTVVTVYNAKIKEDESECKKFDLRVSVENIPRPKNKEGILRSVKINICTRFLGEVDATMSIIDVSMLT GFSPDTDDLKRLSQGVDRYISKFEMDKAPSERASLIIYLDKVSHTEEECLSFKAHQFFEVGLIQPASVTV YDYYTIDDRCTKFYHPSKQSGLLSKICHGDVCRCAEENCFMQHKMDSPVTLDKRIEDACEPGVDYVYKTR LVDTEESSGYDNYIMEILTIIKAGTDENPVGQRRKFISHVKCRESLNLEQNKDYLIWGLSSDLWTMKNEL SYIISKDTWIEKWPNEEECQEPDFQKLCQEFQEFSEAMTMFGCPT >XP_020772460.1 complement C3 [Odocoileus virginianus texanus] MRPTSGPSLLLLLLLASLPMALGSPMYSMITPNILRLESEETVVLEAHGGQGDIPVSVTVHDFPAKRQVL SNENTQLNNGNGYLATVTIKIPASKELKSDKGHKFVTILATFGGVQVEKVVLISLQSGYLFIQTDKTIYT PGSTVLYRVFTVDHKLLPVGQTVIVSIETPDGIPVKRDSQSSHNQFGILALSWNIPELVNMGVWKIKAHY EDSPQQVFSADFEVKEYVLPSFEVQLEPEEKFYYVDDPDGLKINIIARFLYGEHVDGTAFVIFGVQDGDR RISLTHSLTRVPIIDGNGEAILRRQVLLNGVQPSRADALVGKSIYVSATVILQSGSDMVEAERTGIPIVT SPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTQGSNVQSLTQDDGVAKLSINTQNKRDPLT ITVRTKKDNIPEDRQATKTMQALPYNTQGNSNNYLHLSVTRVELKPGETLNVNFHLRTDPGQQAKIRYYT YMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLINANGQREVVADSVWVDVKDSCMG TLVVKSGGKEEKHHRPGQQITLKIEADQGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGS GRDYAGVFTDAGLALKTSQGLETKQRADPLCPQPAVRRRRSVQLMEKRMDKVGQYSGDLRKCCEDGMRDN PMKFPCQRRAQFILQGDACVKAFLDCCEYIAQLRQQHNRDSALELARSDLDDEIIPEEDIISRSQFPESW LWTIIEDFKQADKNGISTKLTNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVV RNEQVEIRAVLYNYREAEDLKVRVELLYNPAFCSLATAKKRHQQTLVIPARSSLAVPYVIVPLKVGLHEV EVKAAVYNHFISDGVKKTLKVVPEGIRVNKTVAIQTLNPEHLGQGGVQRVEVPAADLSDQVPDTESETKI LLQGTPVAQMTEDAIDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGLEKRQQSLELIR KGYTQQLAFRQKNSAYAAFLNRPASTWLTAYVVKVFALSANLIAIDSKDLCETVKWLILEKQKPDGIFQE DGPVIHQEMIGGFKDAREKDVSLTAFVLIALHEAKDICEAQVNSLGRSINKAGDFLENHYRELRRPYTVA IAAYALALLGKLEDDRLTKFLNTAKEKNRWEEPNQKLYNVEATSYALLALLARKDYDTVAPVVRWLNEQR YYGGGYGSTQATFMVFQALAQYQKDVPDHKDLNLDVSIQLPSRNSLVKHRILWESASLLRSEETKENERF TVRAEGKGQGTLSVVTVYHAKLKGKVSCKKFDLQVSIHPAPEPVKKPQDAKGSMILDICTRYLGDQDATM SILDISMMTGFSPDIDDLKLLSSGVDRYISKYEMNKDSNKNTLIIYLDKVSHTVEDCLSFKVHQYFNVGL IQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCRCAEENCFMHHPDEEITLDGRLDKACEPGV DYVYKTRLTRKKLEDDFDEYIMVIEQIIKSGSDEVQVNQERKFISHIKCREALKLKEGAHYLVWGVSSDL WGEKPNISYIVGKDTWVELWPDAEECQDEENQKQCEELANFTENMVVFGCPN
Mafft alignment of selected proteins >NP_000055.2 complement C3 preproprotein [Homo sapiens] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GP--TSGPS-L-LLLLLTHLPLAL--------------- -----------GSPM-YSIITPNILRLESEETMVLEAHDAQ--GDVPVTVTVHD-FPGKK LVLSSEKTVLTPATNHMGNVTFTIPANR-EFKSEK-GRNKFVTVQATFGT-----QVVEK VVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLP-VGR--------TV-MVNIEN P-EGIPVKQ-DSLSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQV-FSTEFEVKE YVLPSFEVIVEPTEKFYYIYN-------EKGLEVTITARFLYGKKVEGTAFVIFGIQDGE QRIS-----LPESLKRIPIEDGSGEVVLSRKVLLDGVQ-NPRAEDL--VGKSLYVSATVI LHSGS---------------DMVQAERSGIPIVTSPYQIHFTK-TPKYFKPGMPFDLMVF VTNP-DGSPAYRVPVAV---QGEDT-----------------------VQSLTQGDGVAK LSINTHPSQ----KPLSITVRTKKQELSEA----------EQATRTMQALPYSTVGNSNN YLHLSVLRTEL----RPGE-TLNVNFLLRMDRA--HEAKIRYYTYLIMNKGRLLKAGRQV REPGQDLV-----------------------------VLPLSITTDFIPSFRLVAYYTLI GASGQREVVADSVWVDVKDSCVGSLVV------KSGQS-EDRQPVPGQQMTLKIEGDHGA RVVLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSS SGQQTAQRA--ELQCPQPA-ARRRR---SVQLTEKRMDKVGKYP-KELRKCCEDGMRE-- NPMRFSCQ---RRTRFIS-------LGE-ACKKVFLDCCNYITELRR------------- QHARASHLGLARSNLDE----DIIAEEN---------IVSRSEFPESWLWN-VEDLKE-P ------------PKNGISTKLM-NIFLKDSITTWEILAVS--MSDKKGICVADPFEVTVM QDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVR-------VELLHNPAFCSLATTK RRHQQT---VTIPPKSSLSVPYVIVPLKT---GLQEVEVKAAVYHH-----------FIS DGVRKSLKVVPEGIRMNKTVAVRTLDPERL-------------------------GREGV QKEDIPPADL-SDQVPDTESETRILLQG-TPVAQMTE----DAVDAERLKHLIVTPSGCG EQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSA--FAAF VK--RAPSTWLTAYVVKVFSLAVNL--IAIDSQVLCGAVKWLILEKQ-KPDGVFQEDAPV ---IHQEMIGGLRN-NNEKDMALTAFVLISLQEAKD--ICEEQVNSLPGSITKAGDFLE- -ANYMNLQRSYTVAIAGYALAQMGR--LKGPLLNKFL----------------------- TTAKDKNRWEDPGKQLY---------NVEATSYALLALLQLKD--------FDFVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D APDHQELNLDVSLQLPSRSS----KITHRIHWESASLLRS-----EET--KENEGFTVTA EGKGQGTLS-----------------------------------------VVTMYHAKAK DQL-T-CNKFDLKVTIKP----------------APET---------------------- ------------------------------------------------------EKRPQD AKNTMILEICTRYRG-DQDATMSILDISMMTGFA------PDTDDLKQLANGVDRYISKY ELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQ-YFNVELIQPGAVKVYAYYNLEESCTR FYHPEKEDGKLNK--------LCRDE-----LCRCAEEN-----CFIQKSD--------- -----------------DKVTLEERLDKACE-------PGVDYVYKTRLVKVQLSNDFD- ---------------EYIMAIEQTIKSGS-DEV-QVGQQRTFISPIKCREALK------- -------------LEEKKHYLMWGLSSDFWG--EKPN-----------------LSYIIG KDTWVEHWPEEDECQDEEN--------QKQCQDLGAFTESMVV----------------- -------FGCPN------- >tr|A5PMP6|A5PMP6_DANRE Complement component c3b, tandem duplicate 1 OS=Danio rerio OX=7955 GN=c3b.1 PE=4 SV=1 M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------LL-QLLLWATLLCQICDGKAFPQRHKRTVW RHMRQIEPVKDPSPS-FSLLAPAKIRPGTKQNILVEGHNLA--QVVEVTVVVYD-YPNSQ TALSRGSVFLNSDNNYSVLQTLEINPNL-LLPDGK---KKYVKLVAQFSN----IYRAEK VMAVSFRSGHIFIQTDKPIYNPGDKVRFRAFVSDLEFRS-SER--------TI-SLEIQN P-DGIAVHGIGRVKA--IDGVFSDIFSLSTVVKYALRI-------------------VQL CLLPAFNVTLTPKTSHLSLD--------AEKLEVEITARYLYGAQVKGVAYVLFGIEING EKKR-----LTSMKQIDDVLNG-GSVSLTMEEIKR--A-YPDINSL--LGSTLYVKASVL TSSGS---------------DLVEAEKSGIKIVKSPYMLTIKD-TPKYYKPGLPLAMTVI VSNH-DGSPTPNIPVKV---TFLE-------------------------SPISVHSGTIN IHINMPKTHILYGNSQILKVETVDPSLKPE----------QQAIQEVYVKPYSTFSGHDN FLHVSVGASRV----VVGG-SVSVQMYIKSSLP-NHRALVEHLTYIVLNKGKIIQAGRVN VK-GQDVT-----------------------------SVHLLITTEMLPAFRFVAYYVL- PWQHRAEVVADSVFVDVEDRCVGSLNV------GPVDGEIVSSYSPGSSFKFQVKGDVGA KVSLVAVDNAIFLLS---KNRLTQKKVWEVVDQADMGCTAGGGKDNMGVFSDAGLMFHSS TGGSTDSKE--D--CSSKT-KRRRR---SAAKLQLRDQLEKAYSDELLQRCCVDGMKE-- IPMPYSCY---RRSLYIT-------EDW-SFFFVRDRVLQSMPKLHAEANVVGVRQDSYR EVVVEEEEEAASVFEED----DLSDLED---------IYVRSKFFESWLWT-DIRLPSTA ------------KSDGLAVFPV-DTVLPDSITQWGFLAVS--ASPEKGVCVAEPYNVRVW KPFFIDLRLPHSVSRNEQVEIKAVIHNYKN-STLEVRSTPSVVMVILEKTEDMCSVAYTG Q-HRQQ---VTVAAGSSKLITYTIIPLKT---GELPLQVTAVAASF-----------MGQ DAVKKNLRVVVEGIQTLKVR-SFVLNPSEK------------------------GGSAGQ QLIQVKKMQL-DAVVPKSVPETFVNVRG-DLLADSID----NSIKEDSLAALIRMPGGCV EQNLARITLPLIAAHYLDRSADWEIVGISRREEAIKYIQRGYENQLNYKKSDDS--YPPY AN--EGTSTWITAYVVKVFSMAHSF--INVNEKHLCGPLLYLLKNKQ-GYDGTFQEDNPV ---YDTSMTGAMRG--SEYKASLTAFVLIALAEAQDKVTCQDQEVNIRDKSRQAAGYLT- -EHFSRLTRPYTAAIACYALAVSNN-ACVKSMLLKFA----------------------- --SPDHSHWPDSNNYFF---------TLEATGYALLALIKSGH--------MEEAEAPFR WLNEHRGIGGGYGST-------------------------QSTMVVLQALSEYLV----K RPPPSDLNLLVQLSVPGRSD-----VRWTFNPNLAYVARS-----SRV--PLDQEFSVAA SGNGKGVLE-----------------------------------------VVTVYHQLPD VYENSTCNGFQLDVSIAE----------------TNE----------------------- -------------------------------------------------------KTSSD VEKSFRLNVNVRALE-ERQVRMVILDIGLPTGFE------PENSDLELLTNSVDRYINNF QVVDNLSDRGSLIIHLFKVSNKEAEMISFRLNQ-KFKVGLLQPSTVKVYQYYNKDKSCSR FYSPPEDKQQLDQ--------ICEGD-----VCRCSQGD-----CCVMKEDF-------- -----------------AFFGKEQRNAAVCN--------GLHHAYRVKLISISQSHYY-- ---------------QYEMEIVQVIKEGT-EEGLNEKERRMFLSHASCRTRLN------- -------------LKEGQEYLVIGPITDVWN--AGSTVSN-------------KYVYTLG KETWVERWPDESECGSTL---------QKKCDELKSFAKKLIE----------------- -------DGCQA------- >tr|B8JKW4|B8JKW4_DANRE Complement component c3a, duplicate 1 OS=Danio rerio OX=7955 GN=c3a.1 PE=1 SV=1 M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------VKLLFL-SAVLLSSALLTL--------------- -----------CDPL-YVLSAPNLLRVGSSENVFVEAQDYS-KNAFEVKITVKN-HPKKD KQILTKSVNLNAQNNFQILTDIKIPDDQNLFSDDPLE-KQYVYLQAIFPD-----HTLEK VVLLSFQSGYIFVQTDKPIYTPSSTVQYRTLSLTPNLKP-LSQ-------TGI-TVEIMN P-QNITVSS-DKVYP--VKGMKSGKYAIPEVASLGIWKVVTRFANTPQKT-FTAEFEVKE YVLPTFEVKLQPSKLFYYVG--------DESLTVDIEAKYLFGKQVEGNAFVMFGVMDGE TKTG-----ITGSLQKIQILKGVGTAELTKQMI-E--T-YKSIDKL--VGQSIYVSVSLL TESGS---------------EMVEAERRGIRIVTSPYTINFKK-TAQFFKPGMPFDVSIY VTNP-DETPAQNVIVEV---NPGGV------------------------RGQTKANGIAK VTVNTQGNV----LTQEITAQTKDPDITDE----------EQAVKKMTAHAYVPKGGSKN YLHIGIDAAEL----EIGD-QMKVNLNTGQSPG----VKDQDYTFMILSKGQIVKIDRFK RQ-GQALI-----------------------------TLSQPVTKEMVPSFRFVAYYHV- ---GANEVVSDSVWVDVKDTCMGKLKL------QVKNK--QNNYNTGEEVKLQISGDPGA RVGLVVVDKAVHVLN---KNRLTQTKIWDVIEKHDTGCTAGGGRDVMGVFSDAGLMFESN TAGGTDTRL--NPECPDPP-KRRRRRRESENLRTITATLAGQYA-DGQRQCCIDGMKD-- NKLGYTCE---RRATYIG-------DGP-ECVKAFLHCCDEMKKRKN------------- IKTEEEEMILARSDDDDD---YYTDSEE---------IVSRTQFPESWLWE-EIDLCD-- -------------NCPASAMEK-AMYLKDSITTWQVLAVS--MSPTLGICVAEPEEIVVF KSLFIDLKMPYSAVRGEQLEIKAIIHNYTP-DKRKVR-------VEFMESADVCSLASKK GKYRTT---VTIPKESSLSVPYVIIPMTL---GNHMIEVKAAAYDA-----------VYT DGVRKGLKVVSEGVLFPLQRPNVELNPVKN----------------------------GD SPIIVRADIP-ADRVPGTPAHTHISITG-EEISQTVE----QAISGSFMGQLIVQPHGCG EQNMIFMTLPVIATHYLDSTNQWEAIGMKRRDEAIGHIKTGYNRQQAYRKPDGS--YAAW ID--RPSSTWLTAYVAKIFAMANDL--ITIEEQVLCSALKWLVLNRQ-LPDGSFEEKAAV ---VHGEMVGDVQG--RDAEASLTAFVTIAMQEGRE--LCGAIVGSLPESIRKAVSFLE- -GKLNKLTNPYAVALTSYAMAGADK--LNKAVLMKFS----------------------- TKGEAGTYWNVPGQQYH---------TREATSYAVLALVKARD--------FNAAGEAVH WLGSQHYSYGGSGTT-------------------------QATIMVFQAVAEYRT----Q VKDSQNFNLEVELAVEGRSK----PSRYTIKRDNRHVSRS-----DKV--DINKDFNVTA KGTGKATLS-----------------------------------------VLTLYYARPV EKK-SDCTLFDLSVKIDK----------------DPET---------------------- -------------------------------------------------------KHADA -IETFKLTMDFFYKNPKSPATMTILDIGIPTGFT------VEYNDLEELTRGKEKYLEKF EMDKALSDRGSLILYLKMVSNKESERIAFRMHK-MLNVGLLQPAAVTIYEYYSPNARCTK YFHPERE-GVIYR--------LCKGD-----MCQCAEEN-----CSLQKK---------- -----------------GGFKDEERNIKACE-------SGMDYVYKVKVKDMELAADAD- ---------------IYQMEVEQVLKEGT-DQV-IEGQVKSFLGRPSCKESLG------- -------------FVQGKSYLIMGKSTDLPK--LGGS-----------------LQYILG EQTWIEYWPTSQESKSAEH--------RDRYIGITELENMLTK----------------- -------EGCAT------- >tr|F1QX13|F1QX13_DANRE Complement component c3a, duplicate 3 OS=Danio rerio OX=7955 GN=c3a.3 PE=1 SV=1 M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------EVKLLFL-SAVLLSSALLTL--------------- -----------CDPL-YVLSAPNLLRVGSSENVFVEAQDYS-GGPLNVRISVKN-FPAKN VEMMQKTVTLTGA-KYQSLTDIQIPGDRNYFSDDE-K-KQYVYLQAHFPS-----VTLEK VVMVSFQSGYLFVQTDKPIYTPGSNVHYRIFSMTPNLKP-FSK-------PGI-TVDITN P-QGITVAS-DTIFA--EKGVKSSIYNIPEVTSLGMWKVVTRYANTPQKT-FTAEFEVKE YVLPTFEVKLKTSKSFYYVGDSKPKNNEDDSLTVDMEAKYLFGKKMDGNAFVVFGVMDGA MKTS-----IVNSLQKVQVFNGVGTAELTREMITK--T-FKNIKDL--VGKSIYVSVNLL TESGS---------------EMVEAEKRGIQIVTSPYTIHYKR-TSQFFKPGMPLGVSVY VTNP-DETPAEDVEVEVLVDGVGGV------------------------NSKTKANGIAK VTVNTKAGV----STLKITATTRDPELANE----------QQADKTMIAQAYKTNLGSKN YLHINIESAEF----EIGD-QMTVYLNTGESPG----VKDQDFTYMILSKGQIVLAERFK RQ-GQTLV-----------------------------SLSLPVTKDMVPSFRFVAYYHV- ---GKDEVVSDSVWVDVKDTCMGKLKV------EVTEK--QKFYETGNEVNLQISGDFGA RVGLVVVDKAVQVLN---KNRLTQSKIWDVIEKHDTGCTGGGGKDSMGVFSDAGLMFESD PAGGTNTRT--EPKCPAPP-KRKRR---SESLQTITTTLAGQYT-EKIRPCCYDGMRN-- NRIGYTCE---RRASYVI-------DGE-ECVKAFLHCCKEVKNHK-------------- -ETEEEELILARKDDEETYEEDYEDYDD---------ITSRKQFPESWLWE-EFDLCD-- -------------KCSKPSKNK-VTYLKDSITTWQILAIS--LSPTHGICVAEPEEIVVF KSFFIDLKVPYSAVRGEQVEIKAIIHNYTPKHLKKVR-------VEFLETAGVCSAASKK GKYRAT---VNVDKDSSIAVSFVIVPMTL---ESQHIEVKASILD-------------YT DGVRKTLKVVSEGVLTKFQSQKLELNPAKK----------------------------GE QPLLLRAGIP-GDQVPGTPVHSYITVTG-EEISQSIE----HAINGSFMGELIKRPGGCG EQNMAKMTLPVVATHYLDNTNQWESVGIDRRKVAINHIKTGYDGQLKYRKPDGS--YAIW IN--TPSSTWLTAYVAKVFAMANDF--FAIEENVICSALKWLVMHKQ-LPDGSFKEDAPV ---YDKSIMGGIEG--QNTDVSLTAFVLIAMQEGKE--ICGGTVGSLHESMRKAVAFLK- -DQLPKLTNPYAVALTSYALANADS--LNKAILMMHS----------------------- TKVNDERFWNVPERQYY---------SIEATAYAVLALVKAKD--------YDTAGEAVH WLAKQKSSHGGYDTT-------------------------QVTIMVFQAVAEYHA----Q TQDLNNFDLNVELVVPGRRK----TDRWTIQRSNVHLARS-----GNV--DLNKDFTVIA KGTGSAILS-----------------------------------------VLTLYYARPF EKK-TDCTFFDLSVKLDK----------------IPET---------------------- -------------------------------------------------------KPGTN --GTYNFILDFFYKNKKNDATMTILDIGLPTGFD------IDEADLKQLSTGKERYIQKY EKNKVLSERGSLIIYLNKVSHEVSEKLVFRMHK-TFNVALLQPASVTIYEYYSPDARCKK YYHPEREDSALYR--------LCKGD-----LCVCAEEN-----CSYQKK---------- -----------------NHVDESKRLIKACE-------PHLDYIYKAKLVKMDLKQDSD- ---------------IYHMKVEKTVKEGT-DTD-VEGKVKQFLARPSCRVSLG------- -------------LVEGKSYLIMGNSVDLPT--LGGS-----------------LQYVIG EQTWIEYWPTSDESKSAEH--------RDRYIGMTAVENMFTT----------------- -------GGCLT------- >XP_024207219.1 complement C3 [Pan troglodytes] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GP--TSGPS-L-LLLLLTHLPLAL--------------- -----------GSPM-YSIITPNILRLESEETVVLEAHDAQ--GDVPVTVIVHD-FPGKK LVLSSEKTVLTPATNHMGNVTFMIPANR-EFKSEK-GRNKFVTVQATFGA-----QVVEK VVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLP-VGR--------TV-MVNIEN P-EGIPVKQ-DSLSSQNQFGILPLSWDIPELVNMGQWKIQAYYENSPQEV-FSAEFEVKE YVLPSFEVIVEPTEKFYYIYN-------EKGLEVTITARFLYGKKVEGTAFVIFGIQDGE QRIS-----LPESLKRIPIEDGLGEVVLSRKVLLEGVQ-NPRAEDL--VGKSLYVSVTVI LHSGS---------------DMVQAERSGIPIVTSPYQIHFTK-TPKYFKPGMPFDLMVF VTNP-DGSPAYRVPVAV---QGEDT-----------------------VQSLTQGDGVAK LSINTHPSQ----KPLSITVRTKKQELSEA----------EQATSTMQALPYSTVGNSNN YLHLSVPRTEL----RPGE-TLNVNFLLRMDRA--HEAKIRYYTYLIMNKGRLLKAGRQV REPGQDLV-----------------------------VLPLSITTDFIPSFRLVAYYTLI GASGQREVVADSVWVDVKDSCVGSLVV------KSGQS-EDRQPVPGQQMTLKIEGDHGA RVVLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSS SGQQTAQRA--ELQCPQPA-ARRRR---SVLLTEKRMDKVGKYP-KELRKCCEDGMRE-- NPMRFSCQ---RRTRFIS-------LGE-ACKKVFLDCCNYITELRR------------- QHARAGHLGLARSDLDE----DIIAEEN---------IVSRSEFPESWLWN-VEDLKE-P ------------PKNGISTKLM-NIFLKDSITTWEILAVS--MSDKKGICVADPFEVTVM QDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVR-------VELLHNPAFCSLATTK RRHQQT---VTIPPKSSLSVPYVIVPLKT---GLQEVEVKAAVYHH-----------FIS DGVRKSLKVVPEGIRMNKTVAVRTLDPERL-------------------------GREGV QKEDIPPADL-SDQVPDTESETRILLQG-TPVAQMTE----DAVDAERLKHLIVTPSGCG EQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSA--FAAF VK--RAPSTWLTAYVVKVFSLAVNL--IAIDSQVLCGAVKWLILEKQ-KPDGVFQEDAPV ---IHQEMIGGLRN-NNEKDMALTAFVLISLQEAKD--ICEEQVNSLPGSITKAGDFLE- -ANYMNLQRSYTVAIAGYALAQMGR--LKGPLLNKFL----------------------- TTAKDKNRWEDPGKQLY---------NVEATSYALLALLQLKD--------FDFVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D VPDHKELNLDVSLQLPSRSS----KITHRIHWESASLLRS-----EET--KENEGFTVTA EGKGQGTLS-----------------------------------------VVTMYHAKAK DQL-T-CNKFDLKVTIKP----------------APET---------------------- ------------------------------------------------------EKRPQD AKNTMILEICTRYRG-DQDATMSILDISMMTGFA------PDTDDLKQLASGVDRYISKY ELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQ-YFNVELIQPGAVKVYAYYNLAESCTR FYHPEKEDGKLNK--------LCRDE-----LCRCAEEN-----CFIQKSD--------- -----------------DKVTLEERLDKACE-------PGVDYVYKTRLVKVQLSNDFD- ---------------EYIMAIEQTIKSGS-DEV-QVGQQRTFISPIKCREALK------- -------------LEEKKHYLMWGLSSDFWG--EKPN-----------------LSYIIG KDTWVEHWPEEDECQDEEN--------QQQCQDLGAFTESMVV----------------- -------FGCPN------- >XP_043322320.1 complement C3 [Cervus canadensis] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------QP--TSGPSLL-LLLLLASLPMAL--------------- -----------GSPM-YSMITPNILRLESEETVVLEAHGGQ--GNIPVSVTVHD-FPAKK QVLSNENTQLNNDNGYLATVTIKIPASK-ELKSDK-G-HKFVTVLATFGD-----VAVEK VVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDHKLLP-VGQ--------TV-IVSIET P-DGIPVKR-DSQSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQV-FSADFEVKE YVLPSFEVQLEPEEKFYYIDD-------PDGLKINIIARFLYGEHVDGTAFVIFGVQDGD RRIS-----LTHSLTRVPINDGNGEAILRRQVLLNGVQ-PSRADAL--VGKSIYVSATVI LQSGS---------------DMVEAERTGIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVY VTNP-DGSPARHIPVVT---QGSNV------------------------QSLTQDDGVAK LSINTQNKR----DPLTITVRTKKDNIPEE----------RQATKTMQALPYNTQGNSNN YLHLSVPRMEL----KPGE-TLNVNFHLRTDPG--QQAKIRYYTYMIMNKGKLLKVGRQD REPGQDLV-----------------------------VLPLTITSDFIPSFRLVAYYTLI NANGQREVVADSVWVDVKDSCMGTLVV------KSGGK-EEKHHRPGQQITLKIEADQGA RVGLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTS QGLETKQRA--DPLCPQPA-VRRRR---SVQLMEKRMDKVGQYS-GDLRKCCEDGMRD-- NPMKFPCQ---RRAQFIL-------QGD-ACVKAFLDCCGYITQLRQ------------- QHSRDSTLELARSDLDD----EIIPEED---------IISRSQFPESWLWTIIEDFKQ-A ------------DKNGISTKLT-NVFLKDSITTWEILAVS--LSDKKGICVADPYEVTVM QDFFIDLRLPYSVVRNEQVEIRAVLYNYREAENLKVR-------VELLYNPAFCSLATAK KRHQQT---LVIPARSSLAVPYVIVPLKV---GLHEVEVKAAVYNH-----------FIS DGVKKTLKVVPEGIRVNKTVAIRTLNPEHL-------------------------GQGGV QRVEVPAADL-SDQVPDTESETKILLQG-TPVAQMTE----DAVDGERLKHLIQTPSGCG EQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQQALELIRKGYTQQLAFRQKNSA--YAAF LG--RPASTWLTAYVVKVFALSANL--IAIDSKDLCETVKWLILEKQ-KPDGIFQEDGPV ---IHQEMIGGFRD-TREKDVSLTAFVLIALHEAKD--ICEAQVNSLGRSINKAGDFLE- -NHYRELRRPYTVAIAAYALALLGK--LEDDRLTKFM----------------------- NTAKEKNRWEEPNQKLY---------NVEATSYALLALLARKD--------YDTVHPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D VPDHKDLNLDVSIQLPSRNS----LVKHRILWESASLLRS-----EET--KENERFTVRA EGKGQGTLS-----------------------------------------VVTVYHAKLK GKV-S-CKKFDLQVSIRP----------------APEP---------------------- ------------------------------------------------------VKKPQD AKGSMILDICTRYLG-DQDATMSILDISMMTGFS------PDIDDLKLLSSGVDRYISKY EMNKD-SNKNTLIIYLDKVSHTVEDCLSFKVHQ-YFNVGLIQPGAVKVYSYYNLDETCIR FYHPDKEDGMLSK--------LCHKD-----TCRCAEEN-----CFMHHLD--------- -----------------EEITLDGRLDKACE-------PGVDYVYKTRLVQKKLEDDFD- ---------------EYIMVIEQIIKSGS-DEV-QVNQQRKFISHIKCREALK------- -------------LKEGAHYLVWGVSSDLWG--EKPN-----------------ISYIIG KDTWVELWPDAEECQDEEN--------QKQCEDLANFTENMVV----------------- -------FGCPN------- >XP_027825575.2 complement C3 [Ovis aries] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------QP--TSGPSLL-LLLLLASLPMAL--------------- -----------GNPM-YSMITPNILRLESEETVVLEAHGGQ--GNIQVSVTVHD-FPAKK QVLSNENTQLNSNNGYLSTVTIKIPASK-ELKSDK-G-HKFVIVVATFGN-----VQVEK VVLISLQSGYLFIQTDKTIYTPGSSVLYRVFTVDHKLLP-VGQ--------TV-FISIET P-DGVLVKR-DSLSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQV-FSTEFEVKE YVLPSFEVQLEPEEKFYYVDD-------PDGLKINIIARFLYGEHVDGTAFVIFGVQDGD RRIS-----LTHSLTRVPINDGNGEAILKRQVLLNGVQ-PSRADAL--VGKSIYVSATVI LQSGS---------------DMVEAERTGIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVY VTNP-DGSPARHIPVVT---QGSNV------------------------QSLTQDDGVAK LSINTQNKR----DPLTITVRTKKDNIPEG----------RQATRTMQALPYNTQGNSNN YLHLSVPRVEL----KPGE-TLNVNFHLRTDPD--QQAKIRYYTYMIMNKGKLLKVGRQE REPGQDLV-----------------------------VLPLTITSDFIPSFRLVAYYTLS NANGQREVVADSVWVDVKDSCMGTLVV------KNGGK-EEKHHRPGQQITLKIEANQGS RVGLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLTFKTS QGLETQQRS--DPQCPKPA-ARRRR---SVQLMEKRMDKVGQYS-GDLRKCCEDGMRD-- NPMKFPCQ---RRAQFIL-------QGD-ACVKAFLDCCEYIARLRQ------------- QHSRDGALELARSDLED----EIIPEED---------IISRSQFPESWLWTIIDDFKQ-A ------------DKNGISTKLM-NVFLKDSITTWEILAVS--LSDKKGICVADPYEVTVM QDFFIDLRLPYSVVRNEQVEIRAVLYNYREAENLKVR-------VELLYNPAFCSLATAK KRHQQT---ITIPARSSVAVPYVIVPLKV---GLHEVEVKAAVYNH-----------FIS DGVKKTLKVVPEGIRVNKTVAIRTLNPEYL-------------------------GQDGV QREEVPAADL-SDQVPDTESETKILLQG-TPVAEMAE----DAIDGERLKHLIQTPSGCG EQNMIGMTPTVIAVHYLDSTEQWEKFGMEKRQEALELIRKGYTQQLAFRQKSSA--YAAF QN--RPPSTWLTAYVVKVFALSTNL--IAIDSRDLCETVKWLILEKQ-KPDGIFQEDGPV ---IHQEMIGGFKD-TREKDVSLTAFVLIALHEAKD--ICEAQVNSLGPSITKAGDFLE- -NHYRELRRPYTVAIAAYALALLGK--LEDDRLTKFL----------------------- NTAKEKNRWEEPNKKLY---------NVEATSYALLALLARKD--------FDTVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D VPDHKELNLDVSIHLPSRNS----LVKHRILWESASLLRS-----EET--KENERFTVRA EGKGQGTLS-----------------------------------------VVTVYHAKLK GKV-S-CKKFDLRVSIRP----------------ALEP---------------------- ------------------------------------------------------VKKPQD AKGSMILDICTKYLG-DQDATMSILDISMMTGFS------PDIDDLKLLSTGVDRYISKY EMNRD-SNKNTLIIYLDKISHTQEDCLSFKVHQ-YFNVGLIQPGAVKVYSYYNLDETCIR FYHPDKEDGMLSK--------LCHKD-----TCRCAEEN-----CFMHHTE--------- -----------------EVITLENRLDRACE-------PGVDYVYKTRLIQKKLEEDFD- ---------------EYIMVIEQIIKSGS-DEV-QVKQERKFISHIKCREALK------- -------------LKEGAHYLVWGVSSDLWG--DKPN-----------------ISYIIG KDTWVELWPEAEECQDEEN--------QKQCEDLASFTENMVV----------------- -------FGCPN------- >KAB0363358.1 hypothetical protein FD754_007514 [Muntiacus muntjak] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------QP--TSGPSLL-LLLLLASLPMAL--------------- -----------GSPM-YSMITPNILRLESEETVVLEAHGGQ--GNIPVSVTVHD-FPAKK QVLSNENTQLNNDNGYLATVTIKIPASK-ELKSDK-G-HKFVTVLATFGG-----VPVEK VVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDHKLLP-VGQ--------TV-IVSIET P-DGIPVKR-DSQSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQV-FSADFEVKE YVLPSFEVQLEPEEKFYYIDD-------PDGLKINIIARFLYGEHVDGTAFVIFGVQDGD RRIS-----LTHSLTRVPINDGNGEAILRRQVLLNGVQ-PSRADAL--VGKSIYVSATVI LQSGRRPRMKEGSSLTGKNHDMVEAERTGIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVY VTNP-DGSPARHIPVVT---QGSNV------------------------QSLTQDDGVAK LSINTQNKR----DPLTITVRTKKDNIPEE----------RQATKTMQALPYNTQGNSNN YLHLSVPRVEL----KPGE-TLNVNFHLRTDPG--QQAKIRYYTYMIMNKGKLLKVGRQD REPGQDLV-----------------------------VLPLTITSDFIPSFRLVAYYTLI NANGQREVVADSVWVDVKDSCMGTLVV------KSGGK-EEKHHRPGQQITLKIEADQGA RVGLVAVDKGVFVLNK--KNKLTQRKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTS QGLETKQRA--DPLCPQPA-VRRRR---SVQLMEKRMDKVGQYS-GDLRKCCEDGMRD-- NPMKFPCQ---RRAQFIL-------QGD-ACVKAFLDCCEYIAQLRQ------------- QHSRHSALELARSDLDD----EIIPEED---------IISRSQFPESWLWTIIEDFKQ-A ------------DKNGISMKLT-NVFLKDSITTWEILAVS--LSDKKGICVADPYEVTVM QDFFIDLRLPYSVVRNEQVEIRAVLYNYREAETLKVR-------VELLYNPAFCSLATAK KRHQQT---LVIPARSSLAVPYVIVPLKV---GLHEVEVKAAVYNH-----------FIS DGVKKTLKVVPEGIRVNKTVAIRTLNPEHL-------------------------GQDGV QRVEVPAADL-SDQVPDTESETKILLQG-TPVAQMTE----DAVDGERLKHLIQTPSGCG EQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQQALDLIRKGYTQQLAFRQKNSA--YAAF LG--RPASTWLTAYVVKVFALSANL--IAIDSKDLCETVKWLILEKQ-KPDGIFQEDGPV ---IHQEMIGGFRD-AREKDVSLTAFVLIALHEAKD--ICEAQVNSLGRSINKAGDFLE- -NHYRELRRPYTVAIAAYALALLGK--LEDDRLTKFM----------------------- NTAKEKNRWEEPNQKLY---------NVEATSYALLALLARKD--------YDTVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D IPDHKDLNLDVSIQLPSRNS----LVKHRILWESASLLRS-----EET--KENERFTVRA EGKGQGTLS-----------------------------------------VVTVYHAKLK GKV-T-CKKFDLQVSIHP----------------APET---------------------- ------------------------------------------------------VKKPQD AKGSMILDICTRYLG-DQDATMSILDISMMTGFS------PDIDDLKLLSSGVDRYISKY EMNKD-SNKNTLIIYLDKVSHTVEDCLSFKVHQ-YFNVGLIQPGAVKVYSYYNLDETCIR FYHPDKEDGMLSK--------LCHKD-----TCRCAEEN-----CFMHHPE--------- -----------------EEITLNGRLDKACE-------PGVDYVYKTRLIQKKLEDDFD- ---------------EYMMVIEQIIKSGS-DEV-QVNQERKFISHIKCREALK------- -------------LKEGAHYLVWGVSSDLWG--EKPN-----------------ISYIIG KDTWVELWPDAEECQDEEN--------QKQCEDLANFTENMVV----------------- -------FGCPN------- >KAB0388260.1 hypothetical protein FD755_003216 [Muntiacus reevesi] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------QP--TSGPSLL-LLLLLASLPMAL--------------- -----------GSPM-YSMITPNILRLESEETVVLEAHGGQ--GNIPVSVTVHD-FPAKK QVLSNENTQLNNDNGYLATVTIKIPASK-ELKSDK-G-HKFVTVLATFGG-----VPVEK VVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDHKLLP-VGQ--------TV-IVSIET P-DGIPVKR-DSQSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQV-FSADFEVKE YVLPSFEVQLEPEEKFYYIDD-------PDGLKINIIARFLYGEHVDGTAFVIFGVQDGD RRIS-----LTHSLTRVPINDGNGEAILRRQVLLNGVQ-PSRADAL--VGKSIYVSATVI LQSGRRPRMKEGSSLTGKNHDMVEAERTGIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVY VTNP-DGSPARHIPVVT---QGSNV------------------------QSLTQDDGVAK LSINTQNKR----DPLTITVRTKKDNIPEE----------RQATKTMQALPYNTQGNSNN YLHLSVPRVEL----KPGE-TLNVNFHLRTDPG--QQAKIRYYTYMIMNKGKLLKVGRQD REPGQDLV-----------------------------VLPLTITSDFIPSFRLVAYYTLI NANGQREVVADSVWVDVKDSCMGTLVV------KSGGK-EEKHHRPGQQITLKIEADQGA RVGLVAVDKGVFVLNK--KNKLTQRKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTS QGLETKQRA--DPLCPQPA-VRRRR---SVQLMEKRMDKVGQYS-GDLRKCCEDGMRD-- NPMKFPCQ---RRAQFIL-------QGD-ACVKAFLDCCEYIAQLRQ------------- QHSRHSALELARSDLDD----EIIPEED---------IISRSQFPESWLWTIIEDFKQ-A ------------DKNGISTKLT-NVFLKDSITTWEILAVS--LSDKKGICVADPYEVTVM QDFFIDLRLPYSVVRNEQVEIRAVLYNYREAETLKVR-------VELLYNPAFCSLATAK KRHQQT---LVIPARSSLAVPYVIVPLKV---GLHEVEVKAAVYNH-----------FIS DGVKKTLKVVPEGIRVNKTVAIRTLNPEHL-------------------------GQDGV QRVEVPAADL-SDQVPDTESETKILLQG-TPVAQMTE----DAVDGERLKHLIQTPSGCG EQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQQALELIRKGYTQQLAFRQKNSA--YAAF LG--RPASTWLTAYVVKVFALSANL--IAIDSKDLCETVKWLILEKQ-KPDGIFQEDGPV ---IHQEMIGGFRD-AREKDVSLTAFVLIALHEAKD--ICEAQVNSLGRSINKAGDFLE- -NHYRELRRPYTVAIAAYALALLGK--LEDDRFTKFM----------------------- NTAKEKNRWEEPNQKLY---------NVEATSYALLALLARKD--------YDTVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D IPDHKDLNLDVSIQLPSRNS----LVKHRILWESASLLRS-----EET--KENERFTVRA EGKGQGTLS-----------------------------------------VVTVYHAKLK GKV-T-CKKFDLQVSIHP----------------APET---------------------- ------------------------------------------------------VKKPQD AKGSMILDICTRYLG-DQDATMSILDISMMTGFS------PDIDDLKLLSSGVDRYISKY EMNKD-SNKNTLIIYLDKVSHTVEDCLSFKVHQ-YFNVGLIQPGAVKVYSYYNLDETCIR FYHPDKEDGMLSK--------LCHKD-----TCRCAEEN-----CFMHHLE--------- -----------------EEITLNGRLDKACE-------PGVDYVYKTRLIQKKLEDDFD- ---------------EYMMVIEQIIKSGS-DEV-QVNQERKFISHIKCREALK------- -------------LKEGAHYLVWGVSSDLWG--EKPN-----------------ISYIIG KDTWVELWPDAEECQDEEN--------QKQCEELANFTENMVV----------------- -------FGCPN------- >KAF4014700.1 hypothetical protein G4228_005895 [Cervus hanglu yarkandensis] MAVSERRGLGRGSPAEWRPWLLLLLLLGGSSGRIHRLTLTGEKRADIQLNSFGFYTNGSL EVDLSLLRLGCQNTEEKAPLVGFSLTRVRSGSIRSYSNRDSHECPLRKNSSSLLVLFLIN TKDLQVQVRKYGEQKKLFISAGLLPESPSEPGLPKSEHMVTPKVDHAGTTAAPDKAKLKP TGSQGDRQGVSGKDQELVLGLGHLNNSYNFSFHVVIGSRAEEGQYNLNFHNCDNSVPGRE QPFDITVMIREKNPEGYLSAAEIPLFKLYMVMSACFLGAGIFWVSILCKNTYNVFKIHWL MAALTFTKSVSLLFHSINYYFINSQGHPIEGLAVMHYITHLLKGALLFITIALIGSGWAF VKYVLSDKEKKIFGIVIPLQVLANVAYIVIESREEGASDYGIWKEILFLVDLICCGTILF PVVWSIRHLQDASGTDGKVAVNLAKLKLFRHYYVMVICYIYFTRIIAILLRVVVPFQWQW LYQLLVEGSTLAFFVLTGYKFQP--ARDNPYL-QLPQEDEEEMQM--------------- ------------EQV-YSMITPNILRLESEETVVLEAHGGQ--GNIPVSVTVHD-FPAKK QVLSNENTQLNNDNGYLATVTIKIPASK-ELKSDK-G-HKFVTVLATFGD-----VAVEK VVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDHKLLP-VGQ--------TV-IVSIET P-DGIPVKR-DSQSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQV-FSADFEVKE YVLPSFEVQLEPEEKFYYIDD-------PDGLKINIIARFLYGEHVDGTAFVIFGVQDGD RRIS-----LTHSLTRVPINDGNGEAILRRQVLLNGVQ-PSRADAL--VGKSIYVSATVI LQSGS---------------DMVEAERTGIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVY VTNP-DGSPARHIPVVT---QGSNV------------------------QSLTQDDGVAK LSINTQNKR----DPLTITVRTKKDNIPEE----------RQATKTMQALPYNTQGNSNN YLHLSVPRMEL----KPGE-TLNVNFHLRTDPG--QQAKIRYYTYMIMNKGKLLKVGRQD REPGQDLV-----------------------------VLPLTITSDFIPSFRLVAYYTLI NANGQREVVADSVWVDVKDSCMGTLVV------KSGGK-EEKHHRPGQQITLKIEADQGA RVGLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTS QGLETKQRA--DPLCPQPA-VRRRR---SVQLMEKRMDKVGQYS-GDLRKCCEDGMRD-- NPMKFPCQ---RRAQFIL-------QGD-ACVKAFLDCCKYITQLRQ------------- QHSRDSTLELARSDLDD----EIIPEED---------IISRSQFPESWLWTIIEDFKQ-A ------------DKNGISTKLT-NVFLKDSITTWEILAVS--LSDKKGICVADPYEVTVM QDFFIDLRLPYSVVRNEQVEIRAVLYNYREAEDLKARP-----WVELLYNPAFCSLATAK KRHQQT---LVIPARSSLAVPYVIVPLKV---GLHEVEVKAAVYNH-----------FIS DGVKKTLKVVPEGIRVNKTVAIRTLNPEHL-------------------------GQGGV QRVEVPAADL-SDQVPDTESETKILLQG-TPVAQMTE----DAVDGERLKHLIQTPSGCG EQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQQALELIRKGYTQQLAFRQKNSA--YAAF LG--RPASTWLTAYVVKVFALSANL--IAIDSKDLCETVKWLILEKQ-KPDGIFQEDGPV ---IHQEMIGGFRD-TREKDVSLTAFVLIALHEAKD--ICEAQVNSLGRSINKAGDFLE- -NHYRELRRPYTVAIAAYALALLGK--LEDDRLTKFM----------------------- NTAKEKNRWEEPNQKLY---------NVEATSYALLALLARKD--------YDTVHPVVR WLNEQRYYGGGYGSTQAITQ--IHPLLCHG---------QQATFMVFQALAQYQK----D VPDHKDLNLDVSIQLPSRNS----LVKHRILWESASLLRS-----EET--KENERFTVRA EGKGQGTLS-----------------------------------------VVTVYHAKLK GKV-S-CKKFDLQVSIRP----------------APEP---------------------- ------------------------------------------------------VKKPQD AKGSMILDICTRYLG-DQDATMSILDISMMTGFS------PDIDDLKLLSSGVDRYISKY EMNKD-SNKNTLIIYLDKVSHTVEDCLSFKVHQ-YFNVGLIQPGAVKVYSYYNLDETCIR FYHPDKEDGMLSK--------LCHKD-----TCRCAEEN-----CFMHHLD--------- -----------------EEITLDGRLDKACE-------PGVDYVYKTRLVQKKLEDDFD- ---------------EYIMVIEQIIKSGS-DEV-QVNQQRKFISHIKCREALK------- -------------LKEGAHYLVWGVSSDLWG--EKPN-----------------ISYIVG KDTWVELWPDAEECQDEEN--------QKQCEDLANFTENMVV----------------- -------FGCPN------- >XP_023100060.1 complement C3-like [Felis catus] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GP--ASGPSLL-LLLLLPILPLAP--------------- -----------GDPM-FSMITPNILRLENEETVLLEAHDLE--NNIAVAVTVHD-FPVKK QVLSSENSALTKDNNHMSTVKIKIPASK-ELTSEK-G-KKFVTIQADFGS-----TVVEK VVLVSFQSGYLFIQTDKPIYTPGSTVLYRIFTVDNDLLP-VGR--------TI-IVSIQT P-DNILIKK-DSLSSQNQVGILSLSWNIPELVNTGQWKIEAHYEDAPQQV-FSAEFEVKE YVLPSFEVQVEPTEKFYYIDD-------PQGLEVTITARFLYGKNVDGIAFVIFGVQDGD QRIS-----LPQSLTRVQIDDGSGEARLERKVLLSGVQ-PSGADAL--VGKSLYVSVTVI LHSGS---------------DMVEAERSGIPIVTSPYQIHFTK-TSKFFKPGMPFDLMVF VTNP-DGSPARNVPVET---QDSRA------------------------RSLTQADGVAK LIINTPNKP----VPLPITVITRKDGILES----------RQATSSMLAQPYKIMGSCSN YLHLSVPRVEL----KPGE-DLNVNIHLRIDPTTTKQKDIYYYTYLIMNKGKLLKVGRQM RELGQDVV-----------------------------ALPLTITEDFIPSFRLVVYYTCL NSNGQREVVADSVWVDVKDSCVGKLVV------KGGRK-EERVHLPGQQMTLKIEGDRGA RVGLVVVDKGVFVLNK--KNKLTQSKIWNVVEKADIGCTAGSGKDYAGVFTDAGLAFQTN TNLQTPDRT--DPECPKPA-TRRRR---SVMLMEKRMDKVGQYP-RQLRKCCEHGMRE-- NPMKFSCQ---RRARFIQ-------HEA-SCVKAFLDCCNYITQLRL------------- NHTRSAHLGLARSDLDE----DIIPEEE---------IISRSQFPESWLWR-IEELSE-P ------------EKDGISTKTM-NIFLKDSITTWEILAVS--LSNKKGICVADPYEVTVM QDFFIDLRLPYSVVRNEQVEIRAVLYNYQDVGELKVR-------VTLLYNPAFCSQATAR KPYQQI---LEIPAKSSMAVPFLLVPLKV---GLHDVEVKAAVYNR-----------FLM DGVKKPLKVVPEGIRVNKTVAVHTLDPENR-------------------------GQNGV QREEVHAIDL-SDQVPDTDSETRILLQG-TPVAQLTE----DAIDAERLKNLIVIPSGCG EQNMKSMTPTVIAVHYLDQTEQWEKLGPTKRKEALQLIEKGYSQQLAYRQDNSA--YAAY LD--RKPSTWLTAYVVKVFSLASNL--IAIQADVICGAVKWLILHRQ-NPDGVFQEDAPV ---MSQAMTGGYQE-NEEKDVSLTAFVLIALEEAKD--ICKQRVNSLEKNINKAGDYIE- -FHYRNLRRPYSVAIAGYALARLGR--LKEDLLEKFL----------------------- STAKEKTSWEEPGKDLY---------NVEATSYALLALLVLKD--------FDSVRPIAS WLNEQRYYEGGYGST-------------------------QATFMVFQALAQFQK----D VPDHKDLNLEVSIELPSRSS----AIRHTILWESASLQRS-----AET--KKNEDFVVTA KGKGQGTLS-----------------------------------------VVTMYHAKLK SNH-T-CKKFDLRVDIRR----------------APED---------------------- ------------------------------------------------------VKRPQE ALDTMILDICTKYLG-EQDATMSILDISMMTGFS------PDTGDLDLLSNGIDRYISMY ELNKAFSNKNTVTIYLDKVR---------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------LPMGI----------------------------------- ------------------------------------------------------------ ------------------- >OWK12416.1 C3 [Cervus elaphus hippelaphus] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------QP--TSGPSLL-LLLLLASLPMAL--------------- -----------GSPM-YSMITPNILRLESEETVVLEAHGGQ--GNIPVSVTVHD-FPAKK QVLSNENTQLNNDNGYLATVTIK------------------------------------- -----------------------------------------------------------T P-DGIPVKR-DSQSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQV-FSADFEVKE YVLPSFEVQLEPEEKFYYIDD-------PDGLKINIIARFLYGEHVDGTAFVIFGVQDGD RRIS-----LTHSLTRVPINDGNGEAILRRQVLLNGVQ-PSRADAL--VGKSIYVSATVI LQSGS---------------DMVEAERTGIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVY VTNP-DGSPARHIPVVT---QGSNV------------------------QSLTQDDGVAK LSINTQNKR----DPLTIT-----------------------ATKTMQALPYNTQGNSNN YLHLSVPRMEL----KPGE-TLNVNFHLRTDPG--QQAKIRYYTYMIMNKGKLLKVGRQD REPGQDLV-----------------------------VLPLTITSDFIPSFRLVAYYTLI NANGQREVVADSVWVDVKDSCMGTLVV------KSGGK-EEKHHRPGQQITLKIEADQGA RVGLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTS QGLETKQRA--DPLCPQPA-VRRRR---SVQLMEKRMDKVGQYS-GDLRKCCEDGMRD-- NPMKFPCQ---RRAQFIL-------QGD-ACVKAFLDCCKYITQLRQ------------- QHSRDSTLELARSDLDD----EIIPEED---------IISRSQFPESWLWTIIEDFKQ-A ------------DKNGISTKLT-NVFLKDSITTWEILAVS--LSDKKGICVADPYEVTVM QDFFIDLRLPYSVVRNEQVEIRA------------VR-------VELLYNPAFCSLATAK KRHQQT---LVIPARSSLAVPYVIVPLKV---GLHEVEVKAAVYNH-----------FIS DGVKKTLKVVPEGIRVNKTVAIRTLNPEHL-------------------------GQGGV QRVEVPAADL-SDQVPDTESETKILLQG-TPVAQMTE----DAVDGERLKHLIQTPSGCG EQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQQALELIRKGYTQQLAFRQKNSA--YAAF LG--RPASTWLTAYVVKVFALSANL--IAIDSKDLCETVKWLILEKQ-KPDGIFQEDGPV ---IHQEMIGGFRD-TREKDVSLTAFVLIALHEAKD--ICEAQVNV-------------- ------------------------------------------------------------ ----KKNRWEEPNQKLY---------NVEATSYALLALLARKD--------YDTVHPVVR WLNEQRYYGGGYGSTQASSPHILHPGNCSPTSSGLISLLKKATFMVFQALAQYQK----D VPDHKDLNLDVSIQLPSRNS----LVKHRILWESASLLRS-----EET--KENERFTVRA EGKGQGTLS-----------------------------------------VVTVYHAKLK GKV-S-CKKFDLQVSIRP----------------APEP--EPRNYTPP------------ -----PAPPPSILL-----------------------------------FSVFLVKKPQD AKGSMILDICTRYLG-DQDATMSILDISMMTGFS------PDIDDLKLIPQFLHHFPTPM LDFLPCQPSPDQPPPSSQVSHTVEDCLSFKVHQ-YFNVGLIQPGAVKVYSYYNL------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GS-DEV-QVNQQRKFISHIKCREALK------- -------------LKEGAHYLVWGVSSDLWG--EKPN-----------------ISYIIG KDTWVELWPDAEECQDEEN--------QKQCEDLANFTENMVV----------------- -------FGCPN------- >XP_018109218.1 complement C3 [Xenopus laevis] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCGLL-SLSLLLLVSGSY--------------- -----------AQTP-CTLITPNLLRVESEETIVIDAQGQN--APFEAEVIIQD-FPQKK LNLVSTKVPLNVNNGFLGTATLKIPSGD-LSKDTK-S-KQYVYVSVKSNV-----CALEK VVLLSYHSGYIFLQTDKTIYTPGSTVLYRIYSMNYKMQP-ISK--------TL-IIEFLT P-DGIIVKR-DTILQDSKSGIISQSHKLPELLSLGVWTISAKYEDTPQQN-YTINFEVKE YVLPSIEIILKPDTNYFYAD--------AESFGVDIQAQYLYGKHVDGYAFVLFGIRKDN VKKG-----IPESLTRVRIDDGEGRAELKRKDLVK--Y-FEKPEDM--LQFGLYVTVSVV TETGS---------------DMVEAEIEHISIVTTPYKILFTK-TSKYFKPGMPFDMMVY VTNP-DGSPARRIPVVV---EPGNV------------------------EGTTQGDGTTR LTMNTPANI----NVLPITVKTRDPTLPPL----------RQATATMTATAYRPSKAHGN YLHISIAGSDI----KPGE-NIPVNFNIRNTDA-GVQNQIQHFTYLIMSRGRILKVGRQQ RQPGQPFV-----------------------------TMSLPVTDTLIPSFRIVAYYIV- NVGGSRDVVSDSLWVDVVDDCMGTLTV------TGDKDRDNAIQTPGSPMKLKLRADHKA YVGLVAVDKGVYVLNS--KFKITQKKVWDSVEKSDIGCTPGSGANSEGVFSDAGLALQTS FGINTAQRS--DAQCPAPA-QRRKR--SSVALIEIKAGKASEYK-DKAKKCCLDGMQE-- NLMGHTCD---RRSRYIL-------DGK-ECVDAFLDCCRYYEKKRE------------A EKLSKDDDTLGRSDEDD----EYMLDSD---------IVSRTEFPESWFWK-VEQMAEKP ------------DVNGISSKTL-NVFLKDSITTWEVLAVS--LSENKGLCVGQPYEIKVM KDFFIDLKLPYSVVRNEQVEIRAILYNYRN-DRIKVR-------VELTHNPEFCSLSTAK KRYRQE---VWIGGLSSTAVPIVIVPLTL---GLHDIEVKASVSAQ--------SGFFGA DGVRKKLKVVPEGMRIAQDVKTVILEPEVK-------------------------GKGGV QEEKVEALNP-KNVVPRTDIDTTITLQG-TPISQMVE----DAIDGNNMNHLIVVPAGCG EQNMISTTPSVIATRYLDASGQWERIGVNRREQALKNMRQGYAQQMAFRKPDNS--YAAW KD--RPASTWLTGYVAKVFGMAQEF--IDIEANVLCGSVKWLILEKQ-KPDGLFQENAPV ---IHQEMVGGITTGAAEGDSSLTAFILIAMLECQR--TCNEHVNNLQVSIDKASSYLV- -GQYPGLKKPYSIAITSYALALAGK--LPNT--NKLL----------------------- SASIGNTHWEEPGKRFI---------SLETTSYALLTLLKMKE--------FDLTGGIVR WLNEQRYYGAVYGST-------------------------QATIVMFQALAQYQT----D IPSVNELNLDVSLHLPERQQ----PLTYRINLENALLARS-----AET--RLNQDFVVKA KGKGQGTMR-----------------------------------------VVTVYHALVT EKE-RKCLNFELSVNVKE----------------VQLA---------------------- -------------------------------------------------------RPPEG AKATVSIEACARHLK-NVDATMSIIDISMMTGFS------PDTDSLDRLMKGVDKYISKY EVNKGANDKGTLILYLDKVSHIDEECVKFYAHQ-YFEVGFIQPASVTVYDYYTPDNRCTK FYHVEEGSALLGR--------ICQGD-----ICRCAEEN-----CFMQQQIE-------- -----------------GKITADMRVNMACA-------PGVDFVYKATLTELQPSDNYD- ---------------NYVMTIKKVIKQGT-DED-PEDKTRNFISHIKCRKALN------- -------------MQLNRDYLIWGVTGDLWR--QPDG-----------------YSYIIG KDTWMEWWPNERECQQREN--------EDLCDDFETVSDNLEI----------------- -------VGCPN------- >XP_040202590.1 complement C3-like [Rana temporaria] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GDRTL-CLILLSYLAGSSY-------------- -----------GQTQ-CTLITPSVLRVDSEETIVVDGHS----STFEVEYFIQD-FPARN LMLARGKINMNGGNKHLGTAKVTIEGKN-FIKDPK-K-KQYLSISVKSSN-PP--CNIEK VILLTFHSGYIFIQTDKPIYTPGTSVQYRLYPVNFNMQP-TNK--------AV-QVDILN P-DGILVKN-EQLYP-DVTGIISKTYPLTDVPSLGVWTISTRYDGTFQE--YTTNFEVKE YVLPTFEVKIKPDRSFMYAN--------DETFSVAIEADYTYGKTVSGNAFVLFSLKKGD ERKT-----VADSLSRIVIDDGKGRATVKRADLLK--I-LKKTEDI--LEYRLHVSATVI TEAGS---------------DWVEAELDNIYIVTSAYKILLTR-TSKYFKPGMPFHFMVL VTNP-DGSPANKIPVVV---NPGSG------------------------QGVTEEDGTSK LIVNTGSNR----TPLKITVKTTIGGLNEK----------LQASAETTITPYQPQSGLGN YLHLTIDTNVA----KPNK-QIFISFHILTSSP-ADQDKVQHFTYLILSKGRIISVGKQK RDQGQGIV-----------------------------TMSLIVTKDLIPSFRIVAYYTI- ----KKELVSDSLWVDVVDECMGTLEV----------DSKKKTAAPSDLIPLTLKADHDS YVGLVAVDKAVFVLNK--KYKITQSKVWDIVEKSDIGCTPGSGANNMDVFYDAGLAVESN FGMVTKQRS--DPSCDAAK-KRKRR--SSAALIEMKNQKALNYNENLERQCCHDGMTS-- NPMGHSCD---RRAKHIL-------KGD-KCVQVFLDCCKYIELKI-------------- KIEKEQDKDLERSDSEG----EYMKDED---------ITVRSAFDESWLWN-IIKITEKP ------------DNNGVSTQQVKNKYLKDSITTWEVLAVS--LSKTNGICVAKPLEIQAF KSFYVDLRLPYSVVRNEQVGIRAVLYNYEN-EVLKVR-------VTLTYNPKFCSLSTPS KKYTKD---VIVKESSTFTVPLIIVPLEV---GMHDVEVKAAVLGG-----------FVA DGVRKQLKVVPEGVRKVETILSEDLEPERK-------------------------GRSGE QVVNVKSLKN-KKIAPQSSISLIVNVKG-SPIADFIE----QSIDGKNLNHLIIIPTGCA EQNMMKLAPLVIATLFLDKTNQWDKVGLHRRTEAISHMQTGYATQLTHRAKDGS--YTAL QG--SPQGTWLTAYIVKIFSLAKRM--IHITDDVLCGSVRWLVLSMQ-KPDGMFQEHFPI GSQYYQKTRGGLGS-SPDPNVAITAFVTIALLESQN--YCKDHVSNLQRSIDKAVQFIS- -EHYGKLTRPHSIALTSYALARAGK--LSDS--TKLM----------------------- SVATGKSQWNDPDSKFWSSQEYGRYISLEATAYALLTLLQIEE--------YDLADSVAQ WLIRSHVDGEQYGTT-------------------------QTIVVLFEALAKYQE----A RENKMVLDMDVSVNLPERKD----PSKYRLNLQSNLNARS-----DET--NINSDFVVKA KGKGRASLT-----------------------------------------VTAVYYEIVT EKE-SECNHFDFTITARD----------------EPHA---------------------- -------------------------------------------------------KRPDN ALGTMSVEVCFRYRG-DKDLTMSIVDVTMMTGFS------PDVDDLKRLQHGVDRYISQF EINKGAKDKGTLIIYLDKISHTEEECLKFNAHR-YFEVGLVQPGSVTIYDYYSPETRCTK FYHTVEGDNLYGR--------ICQGD-----VCRCSEGN-----CLMLQDPK-------- -----------------KSYSALERKDTACQ-------AGMDYVYKATLLETEYANDYD- ---------------RYVMHITNVYKNGT-DEN-AQGQKRTFISHIKCREALK------- -------------FKKGLDYIIFGSFNDVWQ--TAAN----------------TYTYIIG SRSWVEWWPNKRECQNEEY--------EELCDDFYSLSEDITM----------------- -------FGCGV------- >NP_001098552.1 complement component C3-1 precursor [Oryzias latipes] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------RRALQLL-LASLALVSLMSL--------------- ---------IDAGPL-NLMSAPNLLRVGTPENIFVECQDCS-GANQPVTISVKN-HPTKA KTLATTQVTLTNDNNFQGFGQITIPPGD-FSKDPS-V-KQYVYLEAAFPG-----RTLEK VVMVSFQSGYIFIQTDKTLYTPNSKVYYRMFGVTPRMEP-LERLNDAQTDTSI-SIEIVT P-EGIILPL-DPVSL--KSGLHSGDYQLNEIVSPGLWKIVAKFQSNPQES-FSANFEVKE YVLPSFEVKLSSLRPFFYVD--------SETLEIDIKARYLFGQEVNGNAYVVFGVMDQG QKKS-----FPDSLSRVPIENGEGKVVLKREQITK--T-FQDINQL--VGTSIFVSVSVL TESGS---------------EMVEAELRGIQIVKSPYTITFKR-TPKYFKPGMSFDVAVE VLNP-DESPAGNIPVVV---TPGPV------------------------RGFTAANGMAR LTINTATQD----ERLSISAKTDDPGISLN----------RQAEATMQANQYS--TNSKT YIHIGVDTPEV----KLGD-NLKVNLNLNKQPG-----GNQDITYLITSRGQLVKFGRYK TR-GQVLI-----------------------------SLIIPVTQEMLPSFRIIAFYHP- ---SDNEVVSDSVWVDVKDSCMGSLTL------EPKTP--AASYEPRKMFSLKVSGDPGA TVGLVAVDKGVYVLNS--KHRLTQKKIWDEVEKFDTGCTPGGGKNGLSVFFDAGLLFESS TASGTVYRQ--EKKCAAP--SRRRR---ASTIMDVRTTLLSQYKEDLQRECCLDGMKD-- SPVSYTCE---RRSEYIM-------DGGQACVDAFVTCCKEMEKQQ-------------- LEKKEESLQLARSETDD----SYMDSNE---------IVTRSNFPESWLWS-DIILPQCP PNT---------PNCGSTSSVK-NVPLQDSITTWEFTGIS--LSRTHGICVGESLEVIVR KDFFIDLRLPYSAVRGEQLEVKAILHNYRP-ELITVR-------IDLAEEKDTCSAASKR GKYRQE---VNVGAMSTRSVPFIIIPMKE---GTLPIEVKAAVKDS-----------YLS DGVKKDLRVVPPGVLVKAIE-STILDPAHK-------------------------GKNGE QVEVLNSNIPKSNFIPSSPTSTQISLTGREQVSGLVE----NAISGKSMGTLIYQPSGCG EQNMIHMTLPVIATIYLDKTNQWEAVGFQKRAEALQHIKTGYTNELAYLKGDGS--FAVW AD--HGSSSWLTAYVIKVFSMANNL--VAIKKEHICDAVKFLILRAQ-QPDGLFTETGKM ---YHGEMIGDVRG--SDSDASMTAFCLIAMQESRS--LCSATVNTLPGSIDKAVAYLE- -KRLPRLTNPYAVAMTSYALANEGK--LNRDILYKFV----------------------- --SPELTHWPVPGKHLF---------TLEATAYALLALVKTKS--------FEDARPVVR WFNQQQFVGGGYGST-------------------------QATIIVYQAVAEYWA----N AQE-PEYDLKVDILLPGKSK----PDKYEFNRENSYATRT-----SKI-KDINKDIKVKA TGSGEAVLK-----------------------------------------MVSLYYALPE EKE-SDCQKFDVSVQLLP------------------------------------------ -------------------------------------------------------AKNIG NQKVYKLQIEVLYKDSNRDATMSILDIGLQTGFT------PNLDDLKALSGGRFPLISKY EMNTALSERGSLIIYLDKISHTRPEEISFRVQQ-TMEVGVLQPAAVSVYEYYE-QTPCVK FYHPEREGGQLLK--------LCKDD-----ECTCAEEN-----CSMQKN---------- -----------------GQISNDERTSKICESTE---SSKIEYAYKVLVEDVVQKPSID- ---------------IYAMRVQDSIKEGSTDVG-PRGKLRPFLSYPHCRDALN------- -------------LQKGKTYLIMGSSRDIHKDEKQLT-----------------YQYVLG ERTWIEYWPTAEECQGDEH--------RATCLGLDEMLEQFRV----------------- -------FACQQ------- >XP_030274930.1 complement C3-like [Sparus aurata] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GSS-RRTCVTN-LWLLAFLAFFSL--------------- ---------TDGSPL-QVMSAPNLLRVGTTENIFVECQDYT-GGNIPVEIIVMN-HPTKV KRLASTTVTLTNENSFQQLAQIMIPTGD-FSKDPS-I-KQYVYLQARFPD-----RLLEK VVMVSFQSGYIFIQTDKTLYTPESTVLYRMFAVTPLMEP-VERDEETKSDASI-AIEIVT P-EGIILPL-DPVSL--KSGIHSGDYKLGEIVSPGLWKVVAKFHNNPQQS-YSAEFEVKE YVLPSFEVKLTPVSPFFYVD--------SPDFTVNIRATYLFGEEVDGMAYVVFGVMQEG QKKS-----FPGSLQRVQIAKGIGVVTLKREHITQ--T-FKNINDL--VGSSIYVAVSVL TESGS---------------EMVEAELRGIQIVTSPYTIHFKK-TPKYFKPGMSFDIAVE VMNP-DETPAQGVAVVV---DPGEV------------------------EGFTAANGMAK LTINTEAGI----NSLRITAKTKDPLLTRE----------RQASATMTALPYT--TKSNN YIHIGVDTAEL----ELGD-NLKINLNLNRQSN-----QAKDITYLILSRGQLVKKGRYH TR-GQVMI-----------------------------SLIVPVTKEMLPSFRIIAFYHT- ---DGNEVVSDSVWVDVKDSCMGSLKL------ESSRP--APSYEPRRMFRLKVTGDPEA TVGLVAVDKGVYVLNN--KHRLTQKKVWDIVEKYDTGCTPGGGKDGMSVFFDAGLLFESN TASGTPYRQ--ELKCQARSGSRRKR---SNTIMNVTTSLVSKFEDPLERECCSDGMMK-- TPLSYSCE---TRSEYIG-------DGA-ACVKAFLHCCKEMENQL-------------- ADRNEESLQLARSEEDDN---SYMDSSE---------ITSRTQFPESWLWS-DIKLPACP RQT---------PNCDTTTFEK-NVPLQDSITTWQFTGIS--LSRTHGICVGEPLEVIVR KEFFIDLRLPYSAVRGEQIEVKAILHNYSP-DPVTVR-------VDLIEEVDVCSSASKR GKYRQE---VKVGPQTTRSVPFIIIPMKQ---GQYRIEVKAAVKDS-----------SLN DGIMRMLRVVPQGVLIKSPK-IVTLDPANK-------------------------GVGGI QKEVINSEIPKKDLAPNTPTSTQISVTGREQVSALVE----NAVGGQSMGTLIQQPAGCG EQNMIRMTLPVIAATYLDKTNQWEAVGFQKRAEALQHIKTGYTNQLAYRKDDGS--FAVW AK--HKSSSWLTAYVTKVFAMANNL--VAVQRHVICDAVKFLILNAQ-QPDGMFREVGKV ---YHGEMIGDVRG--ADSDASMTAFCLIAMQESRT--LCAATVNSLPGGIDKAVAYLE- -KRLPALTNPYAVAMTSYALAQENK--LNREILYNFI----------------------- --SPEMSHWPVPKGRVY---------TLEATAYGLLALVKAKA--------FEDARPVVR WFNKQQKVGGGYGST-------------------------QATIMVYQAVAEYWA----S AKE-PEYNLDVDILLPGRSK----PDKFNFNRNNHYATRT-----SKT-NDINENVTVTA TGSGEATVT-----------------------------------------MVSLYYALPS EKE-SDCQKFNMSVQLIP------------------------------------------ -------------------------------------------------------DKNDG VETSYKLRIEVLYKDKERDATMTILDIGLLTGFT------VDRNDLDLLSKGRARIISKY EMNTLLSEKGSLIIYLDKVSHTRPEEITFRIHQ-TFKVGVLQPAAVSVYEYYE-QTPCVK FYHPERRAGHLLR--------LCRGD-----ECTCAEEN-----CSMQKK---------- -----------------GKVSNEQRTAMACESTA---ISKIDFVYKVRLEEFTDSQSTD- ---------------IYTMRVLEVIKEGSYDVG-PQNQVRAFLSYQHCRESLD------- -------------LTEGKTYLIMGTSKDIHRDEQNQS-----------------FQYVLG ERTWIEYWPTEAECQTDIH--------RPTCLGMEELVQQYAL----------------- -------FGCEH------- >XP_015824898.1 PREDICTED: complement C3 [Nothobranchius furzeri] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------RRTNLLL-LASLAFASLMSLA-------------- --------EVKPAPL-KLMAAPNLLRVGTAENIFVECQDCD-GGDISVDIKVMN-HPTKT KELAKTTVTLSNNNNFQQLGEITIPPGD-FSRDPT-V-KQYVYLQAKFPD-----RELEK VVLVSFQSGYIFIQTDKTLYTPNSKVYYRMFGLTPEMKP-VEGQN--QADASI-DIQIQT P-DGIILPL-DPVSL--TDGIHSGDYQLSEIVSPGLWKVMARFQSNPQQS-FSAEFEVKE YVLPSFEVKLLPDTPFFYVD--------SDDFRVSIKATYLFGREVYGTAYVVFGVLEDG VKRG-----LPSSLSRVPITNGEGQVTLKRSHLTD--T-FPEIHTL--VGKSLYVAVSVL TEGGS---------------EMVEAQLRGIEIVTSPYKITFLK-TPKYFKPGMSFDVVVE VVNP-DGSPANNVVVEV---VRHNV------------------------QGLTAPNGVAR LTINTQGTD----TSLEIIARTKAPNLPDE----------RQASANMVATPYS--SNTQR YIHIGVDTAEV----KVGD-NLKINLNLNNQPG-----HQTDITYLITSRGRLVKSSRYK TK-GQSLI-----------------------------SLILPVTKELLPSFRIIAFYHP- ---ADNEVVSDSLWVDVKDSCMGSLTL------QSTRP--VPSYEPRKMFNLKITGDPGA TVGLVAVDKGVYVLNN--KHRLTQKKVWDIVEKYDTGCTPGGGSNSMNVFFDAGLLFESS ISLGTPYRQ--ELKCKTT--ARRKR---ATTILSVRTNLMSKYNNERQRECCLDGMKE-- IPLSYTCK---RRAEYIL-------DDP-DCAEAFVHCCNEMQTKR-------------- AENKEDELRLARSESDD----SYMDSQE---------IVSRTNFPESWLWS-DIKLPACP R-----------PNCESTSFVK-NVPLVDSITTWQFTGIS--LSRTLGICIGDPLEVIVR KEFFIDLRLPYSAVHGEQLEIKAVLHNYSP-DVITVS---------------------HK HGLMHL---IDLNSL--------------------------------------------- --------VVPQGVLVQTSQ-DVTLNPTEH-------------------------GQNGQ QVEKLNSNIPRNDLVPNAPTRTDISVTGREQVSGLVE----NVLSGSSLGTLIKAPGGCG EQTMISMTLPVIATLYLDKTNQWETVGFQRRNEAIQHIKNGYRHELIYRKTDGS--FAVW AH--DKSSSWLTAYVAKVFAMANTL--VAVESEHICGAVKYLIINAQ-QPDGMFREIGRV ---YHGEMIGDVRG--KDSDASMTAFCLIAMQEART--VCTQHVTSLQSQIDKAISYLE- -KHLPTLTNPYAVAMTSYALANENK--LNREILFKFA----------------------- --SPELNHWPVPGNKIF---------ALEATAYALLALVKSEA--------FEDARPVVR WFNQQQFVGGGYGST-------------------------QATIMVYQALAEYWS----K ANE-PEYNLNVDILLPGRTK----YDKFNFNRENQFTTRT-----SKF-NDINQDVNVIA TGSGEATVK-----------------------------------------IVSLYYALPK EKE-SDCQQFNMSVDLIP------------------------------------------ -------------------------------------------------------EKITD DERTYRLRIEFLYLNKERDATMSILDIGLLTGFT------VDNDDLNLLSKGPARVIDRY EMDSVLSERGSLIIYLNKVSHTQPEEITFRITQ-PAKVGILQPAAVSIYEYYD-RTHCVK FYHPQRRAGQLLR--------LCKEN-----ECTCAEEN-----CSMQKK---------- -----------------GDISNDERLAKICESTE---TSKIEYAYKVSVENVDFDLSAD- ---------------SYTARVIEVIKEGTTDVG-SLGKLRTFLGYQHCREALQ------- -------------LKQGRTYLVMGSSKDIHRDEQNES-----------------FQYVLG ERTWIEYWPTSEECQSHEH--------RPSCLGLEEMVDQYND----------------- -------FPCQQ------- >XP_038046850.1 complement C3-like isoform X2 [Patiria miniata] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AQ------------------------------------- ----------------YFIVAPNLVRVDVQETILVSVLGTG-ENQIPVTLYFQ--LTGSN DRISETTVFVRQDESQEARLRIRRDQLP-QLQTSG---QQFVTLVASANT-AQLSIDDRR VILLSYQAGFVFIQTDKPLYTPKQRVDIRVVALDQDMVP-VNN--------EM-QVDIIS P-DDIIVER-YKQRP--VDGFLTLSFVFPSNPVFGNWSVSAYYGHQFKAS-STVQFEAKE YVLPKFYVEVAPQSLYIVPE--------TQNLISKVTARYIFGEPVVGNFYVKYGVLEDD GSLM----DLQSKEGRLN-EVGEAFQDLDMNDVKV----ENWAETL--MGKRLVIQAFVT DTATG---------------ETINTNNTQVTFSRTPYKFNWDL-TQRYFKKGLSFSVKAN VQFM-SGLPAEDVPVIA---SATALQGGRRVDLEGAQAGAQAGGGREHLEKISGPQGEVD FRLDVPAAA----TEITITLRTNNPDLVNA---------NTEGTITVLAQA----SSNNE YLVVRVPSGDIRRVQRIGR-QSTVEVQLTHPDN------VGVLNYFVIAGGRIVHKGAKN QV--NLNT-----------------------------ALGFEVTHEMAPSSRVVAYYTD- ---ANGNVVADALLIDVEEKCKNPIGLSFLGLPSEGST--YKSERSGQNVQLEILAKEDT NVGLVAVDEAVFKLRN--YHRLTQKKVFKRMAGYDLGCGPGGGQTSATIFKNAGVTVMTN AQLDVPHRE--ALGCPEPV-RRARR---SAN-DTEREQILSNYE-GVNREYCEKGMRELS GSVQLTCA---QRAKLMAG-RKGLQVDS-PEIRAFFDCCSVL------------------ ----ESSSDRGRVDAGA----GGVNLED---------ILVRSNFPESWLFD-NVITQSLR ------------SDDDDGRVLY-PTTLPDSVTTWVIEAVGVHMREVHEMCVAEPIKLEVR PPFFLDIGMPYSVQRFEQIEIVASVFNYGD-DELEVT-------VYLRGKEGLCSIAQPG EYSEGIT--IQVEAKKPASVKFVIVPLEV---KNIPIEIVAMDASG-----------QHR DAIEKDLTVRPEGYEKKISV-PVTLDPANYRGSPAKQDGGADQFYFHS--QNWGDQGEEK QIDFIRYSVN-RNAIPGSH-KARMSLVG-NVLGSVID----TVLGG--LDKLLRIPGGCG EQTMLGLAPNVYVYTYLKHTDQFTA---ALETSSERYVFNGVKHELTFRKNDGS--YAAF TS--RPSSTWLTAFVAKIFCKAKDF--AFVDDSNICKAMEWLITQRQSQDDGSFTERNAV ---IHKEMSGGVQG-----KASMTAFVLISLLECEC------DAINKDDSVAAATALLE- -DELPDLTRPYAIAITAYALALANS--IRAQEAIQMLKDIAAYNAVSDSRYW--AADDSS FGGGQKPYWYSARPKAI---------EVETTSYALLALLQMEE--------IQYTHAIVN WLTNQENYNGGFVST-------------------------QDTVMALQALSEYAY----K VQQ-YDIDINCEVKCDESEF----DEDFSLNPANALVREQRNIDVPDM--SQEMNVFIST EGAGMGQFK-----------------------------------------FEATYYIPEP DVT-E-CD-FDLLINEDE---------------NLQLD---------------------- -------------------------------------------------------RPEDD NKEYLSYDIQVRYLR-GEKTGMAILDVGLYTGYK------AVQEDLQTVMDNSGGRVERY E-----ETDHSVVFYFEDIPGLEAIRIQFRAER-EFNVGKVQPVAVHVYDYYNPTEECVK FISPKEGSNLLGK--------LCVED-----TCVCAAGK-----CAVDPIKKG------- -----------------RDYKVYDMTQMACA-------SKAHFAYEVTVTDVEDKGNFQ- ---------------FYTMTIDAPLKQGL-DHV-VKDATRVFAKSKSC-DTPD------- -------------LQMTK-YLVIGSGGLPTKDDVGQD----------------IYKYVID DRTFFYEYPTILQVNKSKKW-------QRIHAKLTELKQELVNG---------------- -------EGCAL------- >XP_030852887.1 complement C3 [Strongylocentrotus purpuratus] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GVSITMGSFVL-IFVIAISASLVPG-------------- -------GVTQSSPATFFVTSPNVFRVDVPESVVVTLIRST-PNVQNVQVRVSLRRPGSG VHFSEDTRAVSPGSSQLFTVEIQADN---LMRNEG-D-FQHMVLKAESLD-PSYPFQKET EILVTLQSGYVFVQTDKPIYTPNQDVIIKVMSLDQEMLP-SDR--------EL-HVEIID P-SGTSVKR-LRQTQALPSGFLSGEYRFHSHPALGIWTVSAFYGPEFLVE-SSATFVVKE YVLPTFSVSIETPK-YILAG--------AYSVVSTINAQYVFGKPVLGRYTFKYGVIQDG T--------VQELGERQGLIGDTGRAVVTLDDLSTDFDGPDWFDRF--RGRHFHAKAIVH ESATQ---------------FSEASINTKAIFVDSPYKFSRKR-TVQYFKAGLNLQVNLD LTFA-NGDVATDVPVSV---IATARFPGGRE--EPLRRTDIYGSQVD-LRSNTDDQGGVS MDFGVQSSI----RSIHIVASTHDPQYPN-----------NQADMSFGVSLADS-ANGND YLVIRPRYADY----RSLNVDVTTDFLVQRIGT--TGNEDIDLHFLCITGGKIVLQGVQQ RI-SAFGT-----------------------------NLPITIRSNMVPRMRLIVYYVT- ---MDGSVIADSLLLGVEEQCRQNQEVSLEILPRHVGP-ERTVYEPNGEIRVEVTAPNNS YVGLLAVDKAVYLLRN--KDRMGKRKMYDWMRSYDTGCGPGGGQNTAQIFKDSGMTVLTN AGLDVAIRE--EIECVDEP-TRKKR---SI---------------DRDQQCLYDPTYL-- -----------------------------------VNCLADKPRLR-------------- -----------RSGGGV----GYQN-GD---------VRVREDFKETWFFD-VVSMPE-- ---------------DGSPYLY-PISTSSSITDWHLTAVS--FSPTQGMCISET-TVSVF QDFFIQLHLPYSVVRLEQTQVIATIFNYGI-RGFEIN-------VNFTVEDGLCTAENPT IRH------VFVESRRAASAAFIVRPVEV---GEFQITVTAGGSVN------------KR DIVRKTLLVVPQGVMKRKGR-SVILNPGRVMFSDDVTTPSPNNSFA----QGTTLFGENQ QFEQMTISLP-EDSIPDTE-SCSVKLIG-IPTETTAT----DPIGG--LDHLVRRPRGDG EQTMIFLAPTLFVYQYLIAVGSDTV---EQEARIYDYIADGVVRELTYRQPNGA--YAAW TH--RPGSTWLTAFVVKVFSQANRF--TWVDPVHVEGSINWLIDNNQ-LPSGAFQESRQV ---FYQEMIGAVQG-----ETSMTAFVLISLLESRN--LLVPANQKIDDAIGNATEYLV- -THVEDIDRVYDKAIVTYALALAES--PSMRIANDYLWGDRNEDDTGAVSF---TPDVAN YRDGSQPYWLQRRPSAV---------EIETSGYALLAQIALHD--------YQKAGKVAL WLSNQQNYGGGFVST-------------------------QDTVVALQALAKYT-----E RPEFNTINMDCELATEQITV-------HRYHIGDDYVQEE-----VDVSQSIGRSLTIGC RGTGIAKAY-----------------------------------------VELRYNTEQS DID-T-CP-FHLNTSAVE----------------IDSN---------------------- -------------------------------------------------------ALRSQ NVKGLRITVCTSYNG-DGTTHMSILDVGLYSGFNAVEQTEPEIEGLEEMVNGSE-IISSY E-----ASSRSVIFYLNQIPDDEDLCFTFSAKS-YVVVGNVQAAAVHLYDYYDPDKSCTI SYKPGPGSALLST--------LCSES-----ECICTGGS--LDYCNIDPCP--------- -----------------GPYSIFELERAACA-------SHSSYALKIRIDTEEIQEGFR- ---------------IYRFTVLNPIKTGD-EDV-PHQAQRQLFINEDC-DCPK------- ----------VKGRNIGGTFLLVGQKSLKYTTEQGEE----------------SFRYVYG PTSKLEVWLQTRRPRN-----------AAVFDKLEQFENEMGIE---------------- -------TACSNEI----- >XP_031565662.1 complement C3-like [Actinia tenebrosa] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ITQFK-ENAMFTDSKML-LTLLTIALLMVGC-------------- ----------SSKPS-YVITAPNIFYVGVPQPIHVALFDVKWSHTIELELRVFL-SYGET KVIASQRDRISADNGKLFSLTVGPEVSK--FQSSQ-D-RGFVYLLSRIKG-PELHISKNT KVNVSYSDGVILIQTDKPIYTPKQTVKIRVVPLGFDLMP-SAK--------KI-NLVVKN P-HGIGVRQWESLNT--TLGFISKNIDIGSYALAGIWTIEAYYGHQFLYN-ASSRFEVRE YVLPRFSVKISNPL-YILPT--------LDSFKVKGTAKYTYGKPVQGTATVRLSIAGNP QEKA-----MSLSTSKIKLVNGEFEHPIKMDRIKTKLR-EKWFP----EGYRLHIEADVT EKSTG---------------KTERAVERSVYFVTTPYLIEYVN-TARYFKPGLPFSIVVI VKFT-NGQVARKIPMKV---LVEAFKTDGRK-INASDPKQIQGSGFNWNRANTDDNGRAE FVINIARQV----KELQIKVKTNLQNIPKE----------QNAFKELVMDA----SESHE LMKLRQTNKPA----RVGT-NAVCDAVLTSKTV-------DQLTYFVISRGQIIYSATIK KL-LGIIT-----------------------------TISFKVTSPMSPSSRLFAYYVS- --KETGRVVSDSILLEVEHKFPNPIFL------KDSDR--RNEEPPSMPYNIKIVGTVGT KVGLLGVDQSVYLLSK--SNILTADSVFKKQEELDLGCGAGSGRNSEDMFRNAGMVVLSS ---DIEVSG--EQKCKGEH-KRERR---SIE--------------EHRDFCCSLGNKT-- DTIKRSCF---RRLKDLDVGIYNAKQRY-DCRKTFWMCCIHK-----------------F GRNESGIFARARSGVDL----EALDFGDEQQEDDALNIQTRQYFPETWINK-ELTISQHE RNGECRALLSQELQHKCGSAVL-PVSLPDTMTTWVVQAIG--VSSSAGFGIAKPLHITTF KPFFIYLSMPYSVQRGEEITILATLFNYKN-YDVSVH-------LFLKGDQGFCSAAQPG KMTKLTTSKINIPPQDTVAFPITIVPIKF---GKVPIEVIAVGD-------------IGD DRVLKTLNVVPEGIEERLTQ-SYVLDPQELLKGRKEREENQQNKAEKLSFQSTQAHKDFK QKNKIKLDIP-KNAIPGSI-SAKAYFTG-NMIGQALT----NLAAG-QMVSLLQMPDGCG EQNMVRIAPNVYILHYLKKTNQMTP---ELEKKKEKFIQEGYIHELNYRKKDGS--FALF KREYNKGSTWLTAFVLKVFCQASKLSGVNIDRNVLCQSAKWLI-GNQ-RQDGAFVEHANM -----RSIQGGVYT----SDVTLTAAVVIALKQCQC------GMAEVNSAVERAVGFIE- -KNVTTLADAYSLAITTYALVLANS--PERFRANQKLIQKATYN---------------- --QGSSNRYWETGSKAR---------NIETAGYALMAQVALNR--------FEYAGPIVV WLTKQRSFGGGFVST-------------------------ADTCVALESIAKYSE----Q RQK-FQLDLRIRMK----------NKIMRITKNNAFMQQE-----ADLTEQTGDEVGIQT SGSGVGQMQ-----------------------------------------VDIKYNVPYK ENE-R-CD-FDVKVIATEEGSGRFISTTSSARNNVPARSRSRRALKAKSAKSKKRKDKNQ AKKGKP--GKSKKNKKRRKNNRKKNQKKHQKKNQRKNKRRNKGKSKKREKNNR-KPQSID IPKKLVLRVCTKYRK-SGQTGMAIIEVGLVTGFS------ADEDTLIKLVEKKNNSIERY EL-----SDRAVVFYVNQIVNSRRICIAFHLIR-IFDVGIIQPVPIKVYXYYEPDTKCTL FYNLGSKRRPVGS---------CKKE-----KCKCTQGM-----CAEPDP---------- -----------------YINNIDDLINEVCN--------VYNYAFKGKVVGIDENTDTNP M------------AMTYQINITQIIKQGS-SIF-QTQKAYLFNKPGIC-HYPD------- -------------FEFEDEVFIMGKNK--------------------------NGVQFLD RDTFVKTL-------------------SRRQRFVNKIAKHIRH----------------- -------GKCT-------- >XP_039271128.1 complement C3-like [Styela clava] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------KLLQL-CMQLFIAVLCTRT-------------- ----------SFGQN-HLLIAPQILREGVRETAVLNLYNID--GRIDVVATVKL-EGVTN FEIK------NEDATKPIIMKIKYDKPPGVLPSKR---RQYVELLVSAKQGNKKVYSGQL RMRLIESSGYIHIQTDRPIYRPEERVNVRVIALTQTQSPEVHR--------EV-EIVIRI PLDNVGVEK-KLLRMP-KAKFIDTSFELPEYPVYGIWSIQARYTDEKVVRWSTTTFDVRP YVLPTFNVRVLLDDPYVLVKT----DMSNEYIRGTITAEYSYGRKVSGPYFLAAKLNRPD IKSKFLFYQMPELRRMAKLRGGKQRFEIKATEVLTVIG-DDTFDDLEKEGATIEIDVAVT GEAEG---------------VVESDRSRPIMFVRSPYQLDISR-MSKYYTPRTSFEIKID VLDSVTNSPVKKVELIL---AGPKICGTLDCGNDKCCSNGKCGECEP-IVEESDENGQVN FKIGMDKDP----VKRTYTIQTRKLGIPRE----------NLAKLDFTLHPYI--SSSGS YLQLSAVEKIA----EVGDKNFGIDVWYKSAPS--------RISYVIMARGAIISTGVHI PKKGSVNT-----------------------------NIKIEVKGEMVPSFRFFVYFFS- ----GKELLSNSLWIDVKDACKQELQV------KVPAQ-----VSPSQVFNVEYIGSPNA ILGMSAVDRAAYFLYD--KGRLTRSSVFEALNLYDEGCVREGGKNAQHVFEEAGLQVVGG PYSAKDDFT--NH-CEAKTLKRKKR---SSP-KNIVAKLEKE---ALERKCLMDGSWE-- NLYGTSCV---ERAEAVR-----LKHSF-ECAEKFLKGCEDYLKLKR------------- RSGRSIQANVAGFQAVA--------------------NNVRSNFEENMLWATDVILGP-- ----------------DGKYTR-GVVAKDSITTFEFDTVS--MHEIDGFCVAPTQNVTIF KDTFVQLKLPYSLKRMEQAEIRATVFNYAT-TSKRVT-------VHVKMGEDICSHFRQG KFDDVIT--LEVDANEAEATSLVLMPLRVPDSKQVDIEVKITNEDN-----------VDI DHVKRSILVLPEGEIKNDIKGTYAIDLKNK-------------------------RPSYI DRFKIELRFP-KRYIPGSR-QCWIYPFS-NYMGPIIEFDPVTKQPKNDIKNLIRLPGGCG EQTMLSMGPNVMAHKYLKLVGKMKD-GSAEETGSIDKMQKGFANELKYRTSTAPIVWSVF PR--RAPSVWLNAYVNKIFAQAKQFY-TAMDVGPICTSINWLV-DQQ-NPDGSFDTGGRV ---IHQEMHGAVGS-----TLSLSAYVMMSLVESQS--ICPQYTKKVEISILKATDYLEN SENDRQMEQPYALSLVCFALSVSNPNNPFAKRMRKKLLSKINYSEDNRLAFWKGAPLKTI EGTGTHAYWYKRNAKAI---------DVEATGYALLSILYAQSGEKVTQNILDVTRKIVL WIIQQRDEKGGFSTT-------------------------QDTVVGLQALAEYMIWSSTV EPPTRDVKIDLTISSATGSDWYDEPKRLHLDKSNENSTTPISI-PSNV--ISGGELNIQA RGEGEGTLS-----------------------------------------YRCVYRTLVD EDA---CH-FDISVSTEED--------------RIPLG---------------------- ------------------------------------------------------HVAQGD GAEILKLKLYISKPK-GEPSGQSIVEINLISGYE------VMEDTLVKLSETVDASIERY EI-----AKQKVFLYLSDITEVPK-KLAFRISR-SVYVGRPEPSTVTVYDYYEPSVRCSK FYNVPEQNLKLRTSSCTDKNGLGSED-----ICKCAEGG-----CLTCRTRKQQL----- ENTGCLEGMDGECTICHDPDNCFDLAGTACK---------SDYVYEVKVTSDGVEDPSG- V------------FMDFAIQIVEVYKAGD-DLDVDRNQNRNFSVRRDCFESCRDDKALVD KDGK-----KEPFLKKDRTLLMIGNGVEMNYEDDDNILKGG---------ELPRPHYRLG AGIFVERIYPTTKCKKSKKKA-----EEKKCRKLKKKTPKSTREECLKHIAIHQSCNNLI LLRKRITLGCDRER----K >CAE1304902.1 unnamed protein product [Sepia pharaonis] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------TNVEIQLKGSPRA TVGLSAVDKAVYLIND--KNKLTRKLVKDTMKLGDLACSPGGGLHVGQVFYHAGFVIMTQ DLDRTPATEINNILCSLKQ-ITAEV---SFG----------RYR-RASDFCCISGRYR-- --RGHNCKVAWQEFSYYR-------KTE-FCRSAFMQCCNPAPELPPTRKVITSGE---V DESENERTPSARLRQDA----KSIS------------PIFSLYFPESELFQ-EYRLNP-- ----------------SGLHKL-NFTLPDSLTTWHIQGMS--LSDTSPFCVSKPISLTTF KNVITKLNFPRVVKRLEQIYIKAVVYNYKT-HPINVK-------VNFHETKEICSHAAPG KPFPVK---LSIPAKDIGVAGVVIVPLKA---GNFTIHIEVYEVES-----------NTL EIIEKVLHVKYEGVKKTNSF-SLMLDPSGTYSGHKRHRRHIFKDVTIP--KNEISASQKM QRIIMKLTQP-AEAIDGSA-KGDIVITG-NILGSTIQ----TTLKE--PHKLLDKPYGCG EQTMIFLAPCVYILSYLNSTNQGSQ---VIYENATRYIRLGILREQEFRKMDGS--YAAF DQ--NPSSVWLTAFVLKVFCQASEF--EHVDSHLTKSAMTWLF-QKQ-RLDGSFIEDYPV ---IHQEMVGGVN------DRVMTAFVLISLMECGYK-MHPVEIYRRKNEIDLAIRYLE- -KQMAVTYDTYDMAIISYALALADS--SRKYEARIKLRSMAIENYDKGYLYWR-VGGYSN VTAKKVSAWYHTEESYL---------SVEATAYALLTEMHYGE--------VEHVGPIVK WLIEQRNSAGMFKST-------------------------QDTVMALQALAEYGI----K TIT-PDINLFFNLTSSRAHL----HKHLTVNKETSLWSHI----IPDV--PMNDEVLIES MGIGSAQME-----------------------------------------LNMWYYRPPT QRE-T-CH-FNVTHIIMP----------------IQKD--VRRLI--------------- -KRGCPLCGESCRN-----------------------------------LNGPILRNWDV SDQTICMKIYLRYLG-TSDPGMVVLDMDLLTGYD------THEELLEQLK--LDRLIAKY HK----HGNSRLTLYFNTIPFNKEIEIKLLMFRTMIYMNRLMPAPINVYVYYNATESCTK FYQLSREKDLINL--------LCDSSKK---VCKCAQRD-----CVTCYESMSEL----- -----------------VNIKLKFLEKKSCA--------KEQIVMIVNMTSTFDSSGT-- ---------------AYGFVQEDLSKTDIPD---LEEHVAIFQK-GIC-HCPH------- -------------VKVGEIYLIMANKRVRTLDESNQY----------------RHKFWVD SSGLM--------INKKNQFV------KGEIDIFEQKARSLSRQ---------------- -------AFCG-------- >XP_006565503.2 alpha-2-macroglobulin-like protein 1 isoform X1 [Apis mellifera] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------NKLVFL-VLFICSVTFLHCCD------------- -------AASNVNRG-YVFTAPKKLYAGEIETGCLSLHNLELPAHVHLEL-VFS-FLEGQ EVLASTSAVVKTGTETCLQLAVPSPIYR----------TAILRLKIKFDKYPDYVIKSET DVEIEHDSLLTFVETDKPTYKPGQDVKIRILMLMHDLKP-WQK--------SIPEVWIEN P-SFVKVKQWTNVST--ENGMAQLTFPLSPEPSLGSWHIKVMKKKPYPNLIHSTTFKVEK YVLPKFQMTINSPQ-YILAN--------VENVTWNICVKYSYGKPVKGNLLLKLTPQTPS WTRL---PNLPAIRYETKLDKGDGCTDFVLSGSVLGLAHWK-------MDPNNIVLIAEF TEAGT---------------GIVETTISRTVVLHEALKLEYEHYTPKYFKFGLPYHGKLR VLRY-DDTPAPNEKIQI----CLKVRGKIEWEKDVVDCR----------DFRSSTDGFVD FVVPPQHKNI---VLLSFVATAVDYPTTYYSPEQRWRVFMNQPSTSITVNPWY--SPSDS YLTVARGNQPI----VCGE-KYSFNVMYTTSSN---MNETISFHYSINSKGSILIYGHVK HKPNRDTILNYFEFHNLLGTIESSANKTNKEAIVHRFPLSVKVTPSMAPVSELLLYYVR- ---SDGEIVATTYTIEVGHCFENKV--------KSTWH--TDAQIPGSPTQYHVEAAPRS LCAISAVDKSTLFLSKSESNLMSSTQTFDALKRFH--------PTPKFYFPWENSRCKSA IGPEEMKEE--INHLPQFL-RSKRQ---TIT-----YSKRVNYV-DAVQAFVDFGVIV-- ------------MSDLVL-------ETR-PCPWLFMEYTALSRQYISTNEYMS------M KDNSEFAVAAAAMDSGI----GYVDQNQAQ------MATLRSYFPETWLWE-LVPIGE-- ----------------EGKITI-ERTLPHTITDWVGYTTC--ISPTHGLGIAPPTTITAF QSFFLDYNLPYSIKRGEIMRFKVSLFNYMH-HSLPVK-------IKLEEMEKIDLHLSEP TAS------FCVKPRDNIVHEYILKPRVI---GEVNITVTAFVDIDYPEPCGSETVIFTQ DVIVKPILILPEGFPVEETK-SALICPKDS---------------------------SDD SSFMWELTLP-KDAVPDSG-RAYLNLIG-DILGPALE----------NLDKLIKLPKGCG EQNMILFVPNNHVIKYLDAMRINKP---DLRAKAIRNMEKGYQRELKYRFMDGS--YSAF EE--GESSIWLTAFVLKSFAQAASL--IHIDKYVLESSVSWIT-MNQ-LEDGCFPVIGTV ---FHKSMKGGLQE--HGSSSALTAYILISLLESGV--------PLSPSVVNDAQKCLE- -KGMNN-DDLYTTVLTTYVLALLEH--PKANSSMKSLMNRA------------------- TRYKNLIWWEDKSKPSIG-------LSIEMTAYVILTLLKLGE-----EN-LSEALKAVR WISKQRNSEGGFTST-------------------------QDTILGLEALTKYAM----I VHHNNITDLSV-LVTASKEV----DDVYKLQDENRVILKQ-----IRL-PILPTIVEIFA QGEGCVLIQ-----------------------------------------SNLKYNVASS ----TGSDAFDLSAEVRS----------------VGYG---------------------- -----------------------------------------------------------N ECSLQEITICSRYKMADEESNMALLEVGIISGYV------PDRASLHSLLDPSS-KVKLF E-----EDQDIVTIYFNKLTGQKT-CISFRIIQ-EYFIDHLKPANIKLYDYYQQELTVST NYKIPS---------------ICSSAEPVDEQLTTPNEMIIMKQLSFDESPMNSSFVVNN AELAIPDGMEGPIPV-YVKLNTYDYKTEAATTTNGLPDLTSTFVTEDQTVPTVQTEDEEP IRIDTDNPSITNPLMKEVLRIVKILKINETN---VPSPTRINQSCPICMDVLPSNISDIY CSANSAVKVAIRRFRKVRLLLDLHISREVKRLRAMIEFTLSPNCSCSPLDNPGSFALIIN KDNDFLTSGNQKQTLNDSFYIYGLPLVSGVPCKLAEIRASCLNE------------DN-- -------IQCTYEDPPAYG >NP_033908.2 complement C3 preproprotein [Mus musculus] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GP--ASGSQLLVLLLLLASSPLAL--------------- -----------GIPM-YSIITPNVLRLESEETIVLEAHDAQ--GDIPVTVTVQD-F-LKR QVLTSEKTVLTGASGHLRSVSIKIPASK-EFNSDKEG-HKYVTVVANFGE-----TVVEK AVMVSFQSGYLFIQTDKTIYTPGSTVLYRIFTVDNNLLP-VGK--------TV-VILIET P-DGIPVKR-DILSSNNQHGILPLSWNIPELVNMGQWKIRAFYEHAPKQI-FSAEFEVKE YVLPSFEVRVEPTETFYYIDD-------PNGLEVSIIAKFLYGKNVDGTAFVIFGVQDGD KKIS-----LAHSLTRVVIEDGVGDAVLTRKVLMEGVR-PSNADAL--VGKSLYVSVTVI LHSGS---------------DMVEAERSGIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVF VTNP-DGSPASKVLVVT---QGSNA------------------------KALTQDDGVAK LSINTPNSR----QPLTITVRTKKDTLPES----------RQATKTMEAHPYSTMHNSNN YLHLSVSRMEL----KPGD-NLNVNFHLRTDPG--HEAKIRYYTYLVMNKGKLLKAGRQV REPGQDLV-----------------------------VLSLPITPEFIPSFRLVAYYTLI GASGQREVVADSVWVDVKDSCIGTLVV------KGDPR-DNHL-APGQQTTLRIEGNQGA RVGLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGKNYAGVFMDAGLAFKTS QGLQTEQRA--DLECTKPA-ARRRR---SVQLMERRMDKAGQYTDKGLRKCCEDGMRD-- IPMRYSCQ---RRARLIT-------QGE-NCIKAFIDCCNHITKLRE------------- QHRRDHVLGLARSELEE----DIIPEED---------IISRSHFPQSWLWT-IEELKE-P ------------EKNGISTKVM-NIFLKDSITTWEILAVS--LSDKKGICVADPYEIRVM QDFFIDLRLPYSVVRNEQVEIRAVLFNYREQEELKVR-------VELLHNPAFCSMATAK NRYFQT---IKIPPKSSVAVPYVIVPLKI---GQQEVEVKAAVFNH-----------FIS DGVKKTLKVVPEGMRINKTVAIHTLDPEKL-------------------------GQGGV QKVDVPAADL-SDQVPDTDSETRIILQG-SPVVQMAE----DAVDGERLKHLIVTPAGCG EQNMIGMTPTVIAVHYLDQTEQWEKFGIEKRQEALELIKKGYTQQLAFKQPSSA--YAAF NN--RPPSTWLTAYVVKVFSLAANL--IAIDSHVLCGAVKWLILEKQ-KPDGVFQEDGPV ---IHQEMIGGFRN-AKEADVSLTAFVLIALQEARD--ICEGQVNSLPGSINKAGEYIE- -ASYMNLQRPYTVAIAGYALALMNK--LEEPYLGKFL----------------------- NTAKDRNRWEEPDQQLY---------NVEATSYALLALLLLKD--------FDSVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQT----D VPDHKDLNMDVSFHLPSRSS----ATTFRLLWENGNLLRS-----EET--KQNEAFSLTA KGKGRGTLS-----------------------------------------VVAVYHAKLK SKV-T-CKKFDLRVSIRP----------------APET---------------------- ------------------------------------------------------AKKPEE AKNTMFLEICTKYLG-DVDATMSILDISMMTGFA------PDTKDLELLASGVDRYISKY EMNKAFSNKNTLIIYLEKISHTEEDCLTFKVHQ-YFNVGLIQPGSVKVYSYYNLEESCTR FYHPEKDDGMLSK--------LCHSE-----MCRCAEEN-----CFMQQSQ--------- -----------------EKINLNVRLDKACE-------PGVDYVYKTELTNIELLDDFD- ---------------EYTMTIQQVIKSGS-DEV-QAGQQRKFISHIKCRNALK------- -------------LQKGKKYLMWGLSSDLWG--EKPN-----------------TSYIIG KDTWVEHWPEAEECQDQKY--------QKQCEELGAFTESMVV----------------- -------YGCPN------- >NP_058690.2 complement C3 precursor [Rattus norvegicus] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GP--TSGSQLLVLLLLLASSLLAL--------------- -----------GSPM-YSIITPNVLRLESEETFILEAHDAQ--GDVPVTVTVQD-F-LKK QVLTSEKTVLTGATGHLNRVSIKIPASK-EFNADK-G-HKYVTVVANFGA-----TVVEK AVLVSFQSGYLFIQTDKTIYTPGSTVFYRIFTVDNNLLP-VGK--------TV-VIVIET P-DGVPIKR-DILSSHNQYGILPLSWNIPELVNMGQWKIRAFYEHAPKQT-FSAEFEVKE YVLPSFEVLVEPTEKFYYIDD-------PKGLEVSITARFLYGKNVDGTAFVIFGVQDED KKIS-----LAQSLTRVLIEDGSGEAVLSRKVLMDGVR-PSSPEAL--VGKSLYVSVTVI LHSGS---------------DMVEAERSGIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVF VTNP-DGSPARRVPVVT---QGSDA------------------------QALTQDDGVAK LSVNTPNNR----QPLTITVRTKKEGIPDA----------RQATRTMQAQPYSTMHNSNN YLHLSVSRVEL----KPGD-NLNVNFHLRTDAG--QEAKIRYYTYLVMNKGKLLKAGRQV REPGQDLV-----------------------------VLSLPITPEFIPSFRLVAYYTLI GANGQREVVADSVWVDVKDSCVGTLVV------KGDPR-DNRQPAPGHQTTLRIEGNQGA RVGLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGKNYAGVFMDAGLTFKTN QGLQTDQRE--DPECAKPA-ARRRR---SVQLMERRMDKAGQYTDKGLRKCCEDGMRD-- IPMKYSCQ---RRARLIT-------QGE-SCLKAFMDCCNYITKLRE------------- QHRRDHVLGLARSDVDE----DIIPEED---------IISRSHFPESWLWT-IEELKE-P ------------EKNGISTKVM-NIFLKDSITTWEILAVS--LSDKKGICVADPYEITVM QDFFIDLRLPYSVVRNEQVEIRAVLFNYREQEKLKVR-------VELLHNPAFCSMATAK KRYYQT---IEIPPKSSVAVPYVIVPLKI---GLQEVEVKAAVFNH-----------FIS DGVKKILKVVPEGMRVNKTVAVRTLDPEHL-------------------------GQGGV QREDVPAADL-SDQVPDTDSETRILLQG-TPVAQMAE----DAVDGERLKHLIVTPSGCG EQNMIGMTPTVIAVHYLDQTEQWEKFGLEKRQEALELIKKGYTQQLAFKQPSSA--YAAF NN--RPPSTWLTAYVVKVFSLAANL--IAIDSQVLCGAVKWLILEKQ-KPDGVFQEDGPV ---IHQEMIGGFRN-TKEADVSLTAFVLIALQEARD--ICEGQVNSLPGSINKAGEYLE- -ASYLNLQRPYTVAIAGYALALMNK--LEEPYLTKFL----------------------- NTAKDRNRWEEPGQQLY---------NVEATSYALLALLLLKD--------FDSVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQT----D VPDHKDLNMDVSLHLPSRSS----PTVFRLLWESGSLLRS-----EET--KQNEGFSLTA KGKGQGTLS-----------------------------------------VVTVYHAKVK GKA-T-CKKFDLRVTIKP----------------APET---------------------- ------------------------------------------------------AKKPQD AKSSMILDICTRYLG-DVDATMSILDISMMTGFI------PDTNDLELLSSGVDRYISKY EMDKAFSNKNTLIIYLEKISHSEEDCLSFKVHQ-FFNVGLIQPGSVKVYSYYNLEESCTR FYHPEKDDGMLSK--------LCHNE-----MCRCAEEN-----CFMHQSQ--------- -----------------DQVSLNERLDKACE-------PGVDYVYKTKLTTIELSDDFD- ---------------EYIMTIEQVIKSGS-DEV-QAGQERRFISHVKCRNALK------- -------------LQKGKQYLMWGLSSDLWG--EKPN-----------------TSYIIG KDTWVEHWPEAEECQDQKN--------QKQCEDLGAFTETMVV----------------- -------FGCPN------- >NP_001035559.2 complement C3 preproprotein [Bos taurus] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------KP--TSGPS-L-LLLLLASLPMAL--------------- -----------GNPM-YSMITPNILRLESEETVVLEAHGGQ--GTIQVSVTVHD-FPAKK QVLSNENTQLNSNNGYLSTVTIKIPASK-ELKSDK-G-HKFVTVVATFGN-----VQVEK VVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDHKLLP-VGQ--------TV-FITIET P-DGIPVKR-DSKSSQNQFGILTLSWNIPELVNMGVWKIKAYYEDSPQQV-FSAEFEVKE YVLPSFEVQLEPEEKFYYIDD-------PDGLKVNIIARFLYGEQVDGTAFVIFGVQDGD RRIS-----LTHSLTRVPINDGNGEAILKRQVLLNGVQ-PSRADAL--VGKSIYVSATVI LQSGS---------------DMVEAERTGIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVY VTNP-DGSPARHIPVVT---QGSNV------------------------QSLTQDDGVAK LSINTQNKR----DPLTITVRTKKDNIPEG----------RQATRTMQALPYNTQGNSNN YLHLSVPRVEL----KPGE-TLNVNFHLRTDPG--EQAKIRYYTYMIMNKGKLLKVGRQY REPGQDLV-----------------------------VLPLTITSDFIPSFRLVAYNTLI NAKGQREVVADSVWVDVKDSCMGTLVV------KNGGK-EEKHHRPGQQITLKIEADQGA RVGLVAVDKGVFVLNK--KNKLTQRKIWDVVEKADIGCTPGSGRNYAGVFTDAGLTLKTS QGLETQQRA--DPQCPQPA-TRRRR---SVQLMEKRMDKAGQYS-SDLRKCCEDGMRD-- NPMKFPCQ---RRAQFIL-------QGD-ACVKAFLDCCEYITQLRQ------------- QHSRDGALELARIDLDD----DIIPEED---------IISRSQFPESWLWTVIEDLKQ-A ------------DKNGISTKLM-NVFLKDSITTWEILAVS--LSDKKGICVADPYEVTVM QDFFIDLRLPYSVVRNEQVEIRAILYNYREAENLKVR-------VELLYNPAFCSLATAK KRHQQT---ITIPARSSVAVPYVIVPLKI---GLHEVEVKAAVYNH-----------FIS DGVKKTLKVVPEGVRVNKTVAVRTLNPEHL-------------------------GQGGV QREEVPAADL-SDQVPDTESETKILLQG-TPVAQMTE----DAIDGERLKHLIQTPSGCG EQNMIGMTPTVIAVHYLDSTDQWEKFGLEKRQESLELIRKGYTQQLAFRQKSSA--YAAF QY--RPPSTWLTAYVVKVFALAANL--IAIDSKDLCETVKWLILEKQ-KPDGIFQEDGPV ---IHQEMIGGFRD-TREKDVSLTAFVLIALHEAKD--ICEAQVNSLGRSIAKAGDFLE- -NHYRELRRPYTVAIAAYALALLGK--LEGDRLTKFL----------------------- NTAKEKNRWEEPNQKLY---------NVEATSYALLALLARKD--------YDTTPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D VPDHKELNLDVSIQLPSRNS----AVRHRILWESASLLRS-----EET--KENERFTVKA EGKGQGTLS-----------------------------------------VVTVYHAKLK GKV-S-CKKFDLRVSIRP----------------APET---------------------- ------------------------------------------------------VKKPQD AKGSMILDICTKYLG-DQDATMSILDISMMTGFS------PDVEDLKTLSTGVDRYISKY EMNRD-SNKNTLIIYLDKVSHTVEDCLSFKVHQ-YFNVGLIQPGAVKVYSYYNLDETCIR FYHPDKEDGMLSK--------LCHKD-----TCRCAEEN-----CFMHHTE--------- -----------------KEVTLEDRLDKACE-------PGVDYVYKTRLIQKKLEDDFD- ---------------EYIMVIENIIKSGS-DEV-QVKQERKFISHIKCREALK------- -------------LKEGAHYLVWGVSSDLWG--EKPK-----------------ISYIIG KDTWVELWPEAEECQDEEN--------QKQCEDLANFTENMVV----------------- -------FGCPN------- >NP_990736.3 complement C3 [Gallus gallus] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GC-----CCCP-SCSAFCCSMRSP--------------- -----------PAQM-VTMVTPAVLRLDTDEKVVLEAPGLS--APTEANILVQD-FPQKR KVLFQVRKQLNPAEGMMAIATVKVPVK--LLPPVV-G-KHFVSVVARVGQ-----VTLEK VLLVSLQSGHIFLQTDKPIYTPGSTVLCRLFALSHFMQP-LLK--------TV-IVEVKT P-DNVIIKQ-VPVSSPMRNGIFSINHNLPEVVSLGTWTITAKFEDSQDQV-FSTQFEVKE YVLPSFEVTLDPQEKFLYIDR-------QEDFRVTITARYLYGKNLQGTAFVLFGVVVDD EKKT-----IPQSLQRVKVTDGDGEAVLPMAMLRQ--R-FANLQEL--VGHSLYVTVTVL TESGS---------------DMVEAQRSGIRIVTSPYTIHFTH-TPKYFKPGMPFDLTVY VTNP-DNSPAPRIPVKA---DNFQG------------------------LVSTQRDGTAK LVLNMPANK----NSVPITVRTDQKDLPPE----------RQASRQIVAEAYQSQGNSGN YLHLAVGASQV----QPGD-NLPINFHLKSNRD-DVRKSVSYFTYLILSKGHIVHVGRQP REGDQSLV-----------------------------TMSLPVTANLIPSFRIVAYYHV- ---KPGEIIADSVWVDVKDTCMGSLVV------RGASEADNRVHEPRTPMRLHIEGDHKA HVGLVAVDKAVYVLN---KNKLTQSKVWDTVENSDIGCTPGSGRNHVGVFADAGLSLTSN VNINTEQRS--EVQCAKPA-KRKRR---SVRLIKHKGTKMAEYSDKNLRKCCEDGMKE-- NLMGYSCE---KRATYVL-------DGK-ACTEAFLSCCLYIKGIRD------------- E-ERELQYELARSEVDD----AFLSDED---------ITSRSLFPESWLWQ-VEELTEPP ------------NEQGISMKTL-PIYLKDSITTWEVLAVS--ISENKGLCVADPYEITVM KEFFIDLRLPYSAVRNEQVEVRAILYNYWT-NKIKVR-------VELMYNPALCSASTTK TRYQQI---FQLEPQSSHAVPFVIVPLQL---GQHDVEVKAAVWNS-----------FVS DGVKKKLRVVPEGMRLEKTVKIVELDPKTL-------------------------GNNGV QEVKVKAANL-SDIVPNTESETKVSIQG-NPVSILVE----KATDGTKLKHLIVTPSGCG EQNMIGMTPTVIAVHYLDSTMQWETFGINRRTEAIELIKKGYTQQLAYRKEDGS--FAAF TT--RPSSTWLTAYVAKVFAMAINM--VDIKPEVVCGAIKWLILEKQ-QPDGLFQEDAPV ---IHKEMVGGYHG--AEPSVSLTAFVLSALQESQK--ICKNYVKSLDGSIAKASDYLS- -RKYQSLTRPYTVALTSYALALTGK--LNSEKV--LM----------------------- KFSKDGTHWAERNAHTY---------NIEGTSYALLALLQMEK--------AELTGPVVR WLAQQNYFGGGYGST-------------------------QATILVFQALAQYHV----A LPRQLELNLDVSVLLPRRAN----AITYRIENNNALVARS-----AET--KLNEDFTVKA EGTGKGTMT-----------------------------------------VVTVYNAKVP EKE-NKCDNFDLRVSVED----------------VKAG---------------------- -------------------------------------------------------RELEG VIRSVKITICTRFLD-TVDATMSILDISMLTGFS------PDVQDLKSLSEGVERYISKF EIDHALSNRSNLIIYLDKVSHQVEECIAFRAHQ-HFQVGLIQPASVTVYSYYKIDDRCTR FYHPDKAGGQLRK--------ICHGE-----VCRCAEEN-----CFIRVKKD-------- -----------------NPITVNERIDLACK-------PGVDYVYKVKVVATEETPSHD- ---------------NYIMSILTVIKMGT-DEN-PGGSNRTFVSHKQCRDALS------- -------------LQKGQDYLVWGLASDLWV--TGSR-----------------FSYLIS KDTWLEAWPLEESCQDADL--------QPLCQDFTEFSDNMVL----------------- -------FGCPT------- >XP_020936478.1 complement C3 isoform X1 [Sus scrofa] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GS--TSGPR-L-LLLLLTSLPLAL--------------- -----------GDPI-YTIITPNVLRLESEEMVVLEAHEGQ--GDIRVSVTVHD-FPAKR QVLSSETTTLNNANNYLSTVNIKIPASK-EFKSEK-G-HKFVTVQALFGN-----VQVEK VVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVDHKLLP-VGQ--------TI-VVTIET P-EGIDIKR-DSLSSHNQFGILALSWNIPELVNMGQWKIRAHYEDAPQQV-FSAEFEVKE YVLPSFEVQVEPSEKFYYIDD-------PNGLTVNIIARFLYGESVDGTAFVIFGVQDGD QRIS-----LSQSLTRVPIIDGTGEATLSQGVLLNGVH-YSSVNDL--VGKSIYVSVTVI LNSGS---------------DMVEAERTGIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVY VTNP-DGSPARHIPVVT---EDFKV------------------------RSLTQEDGVAK LSINTPDNR----NSLPITVRTEKDGIPAA----------RQATKTMHVLPYNTQGNSKN YLHLSVPRVEL----KPGE-NLNVNFHLRTDPG--YQDKIRYFTYLIMNKGKLLKVGRQP RESGQVVV-----------------------------VLPLTITTDFIPSFRLVAYYTLI AANGQREVVADSVWVDVKDSCVGTLVV------KGGGK-QDKQHRPGQQMTLEIQGDRGA RVGLVAVDKGVFVLNK--KNKLTQRKIWDVVEKADIGCTPGSGKDFAGVFTDAGLAFKSS KGLQTPQRA--DLECPKPA-ARKRR---SVQLMEKRMDKLGQYS-KELRRCCEHGMRD-- NPMKFSCQ---RRAQFIQ-------HGD-ACVKAFLDCCEYIAKLRQ------------- QHSRNKPLGLARSDLDE----EIIPEED---------IISRSQFPESWLWT-IEEFKE-P ------------DKNGISTKTM-NVFLKDSITTWEILAVS--LSDKKGICVADPYEVVVK QDFFIDLRLPYSVVRNEQVEIRAILYNYREAEDLKVR-------VELLYNPAFCSLATAK KRHQQT---LTVPAKSSVPVPYIIVPLKT---GLQEVEVKAAVYNH-----------FIS DGVKKTLKVVPEGMRVNKTVVTRTLDPEHK-------------------------GQQGV QREEIPPADL-SDQVPDTESETKILLQG-TPVAQMVE----DAIDGDRLKHLIQTPSGCG EQNMIGMTPTVIAVHYLDSTEQWEKFGLEKRQEALELIKKGYTQQLAFRQKNSA--FAAF QD--RLSSTWLTAYVVKVFAMAANL--IAIDSQVLCGAVKWLILEKQ-KPDGVFEENGPV ---IHQEMIGGFKN-TEEKDVSLTAFVLIALQEAKD--ICEPQVNSLLRSINKARDFLA- -DYYLELKRPYTVAIAGYALALSDK--LDEPFLNKLL----------------------- STAKERNRWEEPGQKLY---------NVEATSYALLALLVVKD--------FDSVPPIVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D VPDHKDLNLDVSIHLPSRSA----PVRHRILWESASLLRS-----EET--KENERFTLIA EGKGQGTLSVRNEDPYLLDSLPFLDSSAPEAPFPPQVKWADTLSPFPSHQVVTMYHAKTK GKT-T-CKKFDLKVSIHP----------------APEP---------------------- ------------------------------------------------------VKKPQE AKSSMVLDICTRYLG-NQDATMSILDISMMTGFS------PDTEDLKLLSTGVDRYISKY ELNKALSNKNTLIIYLDKISHTLEDCISFKVHQ-YFNVGLIQPGSVKVYSYYNLDESCTR FYHPEKEDGMLNK--------LCHKE-----MCRCAEEN-----CFMHHDE--------- -----------------EEVTLDDRLERACE-------PGVDYVYKTRLLKKELSDDFD- ---------------DYIMVIEQIIKSGS-DEV-QVGQERRFISHIKCREALK------- -------------LKEGGHYLVWGVSSDLWG--EKPN-----------------ISYIIG KDTWVELWPDGDVCQDEEN--------QKQCQDLANFSENMVV----------------- -------FGCPN------- >XP_038284790.1 complement C3 [Canis lupus familiaris] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GP--ASGPRLL-LLLLLTSLPLAL--------------- -----------GDPM-FSMITPNILRLENKETVVLEAHDLK--ENTEVTVTVHD-FPAKK QVLFREKTDLTSANQYMSTVTIQMPANK-DAKSEK-G-SKFVIVQAAFGA-----TVLEK VVLVSFQSGYLFIQTDKTIYTPSSTVLYRVFTVDHNLLP-IGR--------SV-IISIQS P-DGVTVKR-GSLSSQNQDGILSQSWYIPELVNMGQWKIQAHYEDAPEQV-FSAEFEVKE YVLPSFEVQVEPAQKFYYIDS-------TEGLDVTIMARFLYGKEVDGTAFVIFGVQDGD RRIS-----LSQSLTRILIEDGNGVATLKRNVLLEGVR-PSRPDAL--VGKSLYVSATVI LHSGS---------------DMVEAESNAIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVF VTNP-DGSPAPHVPVGI---QNYRV------------------------QALTQKDGVAK LTINTPDSK----KPLHITVSTKKEGILES----------RQATRTMEVQPYNTIGNSRN YLHLSVPRMEL----KPGE-TLNVNFHLRTDPS--KEAQIRYYTYLIMNKGKILKVGRQE RESGQDLV-----------------------------VLPLTITSDFIPSFRLVAYYTVI GSSGQREVVADSVWVDVKDSCMGTLVV------KGSGK-EQRSHLPGQQTTLIIQGDPGA RVGLVAVDKGVFVLNK--KNKLTQSKIWNVVEAADIGCTAGSGKDYAGVFMDAGLALKTN KELQTPQRR--DLECPKPA-ARRRR---SVVLTEKRMDKVGQYP-KELRKCCEGGMRD-- NPMKFSCE---RRAQFVS-----REESE-SCVKAFLECCKYITQLRL------------- NYSRMDNLGLARSDMDE----ELFLEED---------IVSRSQFPESWLWT-IEILNE-P ------------EKNGISTKTM-NVFLKDSITTWEILAVS--LSKKKGICVADPYEVTVL QDFFIDLRLPYSVVRNEQVEIRAILYNYQEREDIKVR-------VELLYNPAFCSLATSK KSYQQI---VNIPAKSSVAVSYVIVPLKI---GLHEVEVKAAVYRH-----------FAN DGVKKILKVVPEGILVNQTLAIRTLDPEAK-------------------------GQEGV QREEVHAADL-GDQVPDTESETRILLQG-TPVAQMVE----DAIDGDRLKHLIVTPSGCG EQNMIGMTPTVIALHYLDQTEQWDKFGLEKRQEALELIKKGYTQQLAFRQPNSA--FAAF QN--RPSSTWLTAYVVKVFSLATNL--IAIEAQVLCGAVKWLILEKQ-KPDGIFQEDGPV ---IHQEMTGGFRE-AEEKSVSLTAFVLIALKEAED--ICIGQVNILPSSIEKAGNYLA- -AHYQNLRRPYSVAIAGYALAHLDK--LEGDNLRKFL----------------------- NTARDRNRWVEPGKKLY---------NVEATSYALLALLLLKD--------FDNVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D VPNHKDLNLQVSINLPSRST----EIKHHIVWDSPSLQRS-----EET--KKNENFEVIA KGKGQGTLS-----------------------------------------VVTMYYAKLK NKA-T-CKKFDLRVDIQP----------------APEN---------------------- ------------------------------------------------------VKRPQD ALNSMTLNICTRYLG-DEDATMSILDISMMTGFS------PDTCDLNQLSSGIERYISKY ELNKAFSNKNNVILYLEKISHNQEDCISFRVHQ-YFKVGLIQPGSVKVYSYYNLDESCTR FYHPEKEDGQLSK--------LCHKD-----MCRCAEEN-----CFMQQVY--------- -----------------DKVTKDERLDKACE-------PGVDYVYKTRLLRKEPAEDFD- ---------------EYVMAVEQIIKSGS-DEV-ARGQERRFISHIRCREALK------- -------------LQDGKRYLVWGVSTDLWG--EKPK-----------------INYIIG KDTWVEMWPEADECQDEEN--------EKRCQDLASFTDDMIT----------------- -------FGCPN------- >XP_008251121.2 PREDICTED: complement C3 alpha chain isoform X1 [Oryctolagus cuniculus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------M-NVFLKDSITTWEILAVS--LSDKKGICVADPYEVTVM QDFFIDLRLPYSVVRNEQVEVRAVLYNYRESDSLKVR-------VELLYNPAFCSLATAK KNHQQT---VTIPPKSSLPIPYVLVPLKI---GLQEVEVKAAVYNR-----------FIS DGVKKTLKVVPEGMPINKTVAVRTLDPENL-------------------------GQGGV QKEEIPPADI-SDQVPGTESETKILLQG-TPVAQMTE----DAIDGERLKHLIVTPSGCG EQNMIAMTPTVIAVHYLDHTEQWDKFSLEKRQEALELIKKGYTQQLAFKQPNSA--YAAF LN--RAPSTWLTAYVVKVFSLAVNL--IAIDSQVLCGAVKWLIMEKQ-KPDGVFQEDAPV ---IHQEMIGGQRN-SVEKEAALTAFVLIALQEARE--ICEEQVNSLAASINKSRDFLA- -ANYMNLQRPYSVAIAGYALAQQDK--LRGAFLNKFL----------------------- SKAKEKNRWEEPGQRLY---------NVEATSYALLALLLLRD--------FDSVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQT----D VPDHKDLNMVVSIQLPSRSS----PVKHRIVWDSASLLRS-----EET--KENQGFTLTA QGKGQGTLS-----------------------------------------VVTTYFAKVK GKV-T-CKKFDLRVNIRP----------------APET---------------------- ------------------------------------------------------VKKPQD AKSTMILDICTRYLG-DEDATMSILDISMMTGFV------PDTDDLNLLSTGVDRYISKY ELNKAFSNKNTLIIYLDKISHSREECLSFKVHQ-YFNVGLIQPGAVKVYSYYNLEETCTQ FYHPEKEDGMLSK--------LCHKE-----MCRCAEEN-----CFMQQLD--------- -----------------EKVTLNDRLDKACE-------PGVDYVYKTKLVQVERADDFD- ---------------EYLMVVENTIKSGS-DEV-QAGQQRRFISHIKCRDALK------- -------------LKDGKHYLVWGLSSDLWG--EKPN-----------------TSYIIG KDTWVEFWPEKEECQDEEN--------QKHCEDLDAFAESMVV----------------- -------FGCPN------- >XP_024092530.1 complement C3 isoform X1 [Pongo abelii] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GP--TSGLS-L-LLLLLTHLPLAL--------------- -----------GSPM-YSIITPNILRLESEETVVLEAHGVQ--GDVPVTVTVHD-FPGKK LVLSSEKTVLTPATSHMGNVTFTIPANR-EFKSEK-GRNKFVTVQATFGP-----QVVEK VVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLP-VGR--------TV-MVNIEN P-DGVPVKQ-DSLSSQNQFGILPLSWDIPELVNMGQWKIQAYYENSPQQV-FSAEFEVKE YVLPSFEVIVEPTEKFYYIYN-------EKGLEVTITARFLYGKKVEGTAFVIFGIQDGE QRIS-----LPESLKRIPIEDGSGDAVLSRKVLLDGVQ-NPRAEDL--VGKSLYVSVTVI LHSGS---------------DMVQAERSGIPIVTSPYQIHFTK-TPKYFKPGMPFDLMVF VTNP-DGSPAYRVPVAV---QGEDA-----------------------VQSLTQGDGMAK LSINTHPSQ----KPLSITVRTKKQELSEA----------EQATRTMQAQPYSTVGNSNN YLHLSVPRTEL----RPGE-TLNVNFLLRMDRA--HEAKIGYYTYLIMNKGKLLKAGRQV REPGQDLV-----------------------------VLPLSITTDFIPSFRLVAYYTLI GASGQREVVADSVWVDVKDSCVGSLVV------KSGQT-EDRQPVPGQQMTLKIEGDHGA RVGLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSS TGQQTAQRA--ELQCPQPA-TRRRR---SVQLTEKRMDKVGKYP-KELRKCCEDGMRE-- NRMRFSCQ---RRTRFIS-------LGE-ACKKAFLDCCNYMTELRR------------- QHTRASHLGLARSNLDE----DIIAEEN---------IVSRSEFPESWLWN-IEDLKE-Q ------------PKNGISTKLM-NIFLKDSITTWEILAVS--MSDKKGICVADPFEVTVM QDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNEELKVR-------VELLHNPAFCSLATTK RRHQQT---VTIPAKSSLSVPYVIVPLKT---GLQEVEVKAAVYHY-----------FIS DGVRKSLKVVPEGIRMNKTVAVRTLDPERL-------------------------GREGV QKEDIPPADL-SDQVPDTESETRILLQG-TPVAQMTE----DAIDAERLKHLIVTPSGCG EQNMISMTPTVIAVHYLDETEQWEKFGPEKRQGALELIKKGYTQQLAFRQPSSA--YAAF VK--RAPSTWLTAYVVKVFSLAVNL--IAIDSQVLCGAVKWLILEKQ-KPDGVFQEDAPV ---IHQEMIGGLRN-NNEKDMALTAFVLISLQEAKD--ICEEQVNSLPGSITKAGDFLE- -ANYMNLQRSYTVAIAGYALAQMDR--LKGPLLNKFL----------------------- TTAKDKNRWEDPGKQLY---------NVEATSYALLALLQLKD--------FDFVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D VPDHKELNLDVSLQLPSRSS----KITHRIHWESASLLRS-----EET--KENEGFTVTA EGKGQGTLS-----------------------------------------VVTMYHAKAK DQL-T-CNKFDLKVTIKP----------------APET---------------------- ------------------------------------------------------EKRPQD AKNTMILEICTRYRG-DQDATMSILDISMMTGFA------PDTDDLKQLANGVDRYISKY ELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQ-YFNVELIQPGAVKVYAYYNLAESCTR FYHPEKEDGKLDK--------LCRDE-----LCRCAEEN-----CFIQKLD--------- -----------------DKITLEERLDKACE-------PGVDYVYKTRLVKAQLSNDFD- ---------------EYIMAIEQIIKSGS-DEV-QVGQQRTFISPIKCREALK------- -------------LEERKHYLMWGLSSDFWG--EKPN-----------------LSYIIG KDTWVEHWPEEDECQDEEN--------QKQCQDLGTFTENMIV----------------- -------FGCPN------- >XP_010726629.1 complement C3 [Meleagris gallopavo] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GP--LLLPLLL-GVLLLHVVPT----------------- -----------PAQM-VTMVTPAVLRLVTDEQVVLEAPGLT--SPTEANILVQD-FPQKR KVLFQIRKQLNPAEGMMATATIKVPVK--LLPQVV-G-KHFVSVVARVGQ-----VTLEK VLLVSLQSGHIFLQTDKPIYTPGSTVLCRLFALSRFMQP-LLK--------TV-IVEVKT P-DNVIIKQ-VPVSSPKRNGIFSINHNLPEVVSLGTWTITAKFEDSQDQV-FSTQFEVKE YVLPSFEVTLDPQEKFLYIDR-------QEDFRVFIKARYLYGKNLQGTAFALFGVMVDD ERKT-----IPQTLQRVKVTDGDGEVVLPMAMLRQ--R-FANLQEL--VGHSLYVTVTVL TESGS---------------DMVEAQRSGIRIVTSPYTIHFTH-TPKYFKPGMPFDLTVY VTNP-DNSPAPRIPVKA---DNFQG------------------------LVSTQRDGKAK LVLNMPANK----NSVPITVRTAQKDLPPE----------RQASQQMVAEAYQSQGNSGN YLHLAVGASQV----QPGD-NLPVNFHLKSNRE-DVRRSVSYFTYLILSKGHIVHVGRQP REGDQSLV-----------------------------TMSLPVTANLIPSFRIVAYYHV- ---KPGEIVADSVWVDVKDTCMGNLVV------KGASEADNRVHEPRTPMRLRIEGDHKA HVGLVAVDKAVYVLN---KNKLTQSQVWDTVEKSDIGCTPGSGRDHVGVFADAGLSLATN VNIKTEQRG--EVECAKPA-KRKRR---SVKLIKYKGTKMAEYNDRNLRKCCEDGMKE-- NLMGYSCE---KRATYIL-------DGK-ACTDAFLNCCLYIKGIRD------------- E-ERDLHYELARSEADD----AFLADED---------ITSRSLFPESWLWQ-VEELTEPP ------------NELGISTKTL-PIYLKDSITTWEVLAVS--LSEKKGLCVADPYEITVM KEFFIDLRLPYSAVRNEQVEVRAILYNYWK-SKIKVR-------VELMYNPALCSASTSK TRYQQI---LQLEPQTSHAVPFVIVPLQL---GQHDVEVKAAVWES-----------FVS DGVKKKLRVVPEGMRLEKTVKIVELDPKTL-------------------------GNNGV QEVKVKAANL-SDIVPNTESETKVSIQG-NPVSILVE----KAIDGTKLKHLIVTPSGCG EQNMIGMTPTVIAVHYLDSTMQWETFGINRRAEAIELIKKGYTQQLAFRKDDGS--FAAF TN--RPSSTWLTAYVAKVFAMAINM--VDIKPEVVCGAIKWLILEKQ-KPDGLFQEDAPV ---IHKEMVGGYHG--AEPSVSLTAFVLTALQESQK--ICKNYVKSLDGSIAKASDYLS- -RKYQSLTRPYTVALSSYALALTRK--LNSEKL--LM----------------------- KFSKDDTHWAERNAHTY---------NIEGTSYALLALLQMEK--------TELTGPVAR WLAQQNYFGGGYGST-------------------------QATILVFQALAQYHV----V LPRQMELNLDVSVLLPRRAN----AITYRIENSNALVARS-----AET--KLNEDFTVKA EGTGKGTMT-----------------------------------------VVTVYNAKVP ENE-NKCDNFDLRVSVED----------------VKTA---------------------- -------------------------------------------------------RDLEG AIRSVKITICTRFLD-TVDATMSILDISMLTGFS------PDVQDLKSLSEGVERYISKF EIDHSLSNRSNLIIYLDKISHQVEECIAFRAHQ-HFQVGLIQPASVSVYSYYKIDDRCTR FYHPDKDGGQLRK--------ICHGD-----VCRCAEEN-----CFTRQKKD-------- -----------------NPITVNERIDLACK-------PGVDYVYKVKVVATEETSSHD- ---------------NYIVTILSVIKMGT-DED-PLGSNRTFVSHKQCRDALS------- -------------LQKGQDYLVWGLASDLWV--TGSR-----------------FSYLIG KDTWLEAWPLEESCQDADL--------QQLCQDFIEFSEAMTM----------------- -------FGCPS------- >XP_017906433.1 PREDICTED: LOW QUALITY PROTEIN: complement C3 [Capra hircus] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------QP--TSGPSLL-LLLLLASLPMAL--------------- -----------GNPM-YSMITPNILRLESEETVVLEAHGGQ--GNIQVSVTVHD-FPAKK QVLSNENTQLNSNNGYLSTVIIKIPASK-ELKSEK-G-HKFVIVVATFGN-----VQVEK VVLISLQSGYLFIQTDKTIYTPGSSVLYRVFTVDHKLLP-VGQ--------TV-FISIET P-DGVLVKQ-DSLSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQV-FSTEFEVKE YVLPSFEVQLEPEEKFYYVDD-------PDGLKINIIARFLYGEQXDGTAFVIFGVQDGD RRIS-----LTHSLTRVPINDGNGEAILKRQVLLNGVQ-PSRADAL--VGKSIYVSATVI LQSGS---------------DMVEAERTGIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVY VTNP-DGSPARHIPVVT---QGSNV------------------------QSLTQDDGVAK LSINTQNKR----DPLTITVRTKKDNIPEG----------RQATRTMQALPYNTQGNSNN YLHLSVPRVEL----KPGE-TLNVNFHLRTDPS--QQAKIHYYTYMIMNKGKLLKVGRQD REPGQDLV-----------------------------VLPLTITSDFIPSFRLVAYYTLI NANGQREVVADSVWVDVKDSCMGTLVV------KNDGK-EEKKHRPGKQITLKIEANHGS RVWLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLTFKTS QGLETQQRS--DPQCPKPA-ARRRR---SVQLMEKRMDKVGQYS-GDLRKCCEDGMRD-- NPMKFPCQ---RRAQFIL-------QGD-ACVKAFLDCCEYIARLRQ------------- QHSREGALELARSDLDD----EIIPEED---------IISRSQFPESWLWIIIDDFKQ-P ------------DKNGISTKLT-KVFLKDSITTWEILAVS--LSDKKGICVADPYEITVM QDFFIDLRLPYSVVRNEQVEIRAILYNYREAENLKVR-------VELLYNPAFCSLATAK KRHQQN---IMIPARSSVAVPYVIVPLKV---GLHEVEVKAAVYNH-----------FIS DGVKKTLKVVPEGIRVNKTVAIRTLNPEYL-------------------------GQDGV QREEVPAADL-SDRVPDTESETKILLQG-TPVAEMAE----DAIDGERLKHLIQTPSGCG EQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQEALELIRKGYTQQLAFRQKSSA--YAAF QN--RPPSTWLTAYVVKVFALSANL--IAIDSRDLCETVKWLILEKQ-KPDGIFQEDGPV ---IHQEMIGGFKD-AREKDVSLTAFVLIALHEAKD--ICEAQVNSLGRSITKAGNFLE- -NHYRELRRPYTVAIAAYALALLGK--LEDDRLTKFL----------------------- NTAKEKNRWEEPNKKLY---------NVEATSYALLALLARKD--------FDTVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D VPDHKELNLDVSIHLPSRNS----LVKHRILWESASLLRS-----EET--KENEPFTVRA EGKGQGTLS-----------------------------------------VVTMYHAKLK GKV-S-CKKFDLRVSIHP----------------TLEP---------------------- ------------------------------------------------------VKKPQD AKGSMILDICTKYLG-DQDATMSILDISMMTGFS------PDIDDLKLLSTGVDRYISKY EMNRD-SNKNTLIIYLDKVSHTQEDCLSFKVHQ-YFNVGLIQPGAVKVYSYYNLDETCIR FYHPDKEDGMLSK--------LCHKD-----TCHCAEEN-----CFMHHTE--------- -----------------EAITLEDRLDRACE-------PGVDYVYKTRLLQKKLEEDFD- ---------------EYIMVIEQIIKSGS-DEV-QVKQERKFISHIKCREALK------- -------------LKEGAHYLVWGVSSDLWG--DKPN-----------------ISYIIG KDTWVELWPEAEECQDEEN--------QKQCEDLASFTENMVV----------------- -------FGCPN------- >XP_034802768.1 complement C3 [Pan paniscus] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GP--TSGPS-L-LLLLLTHLPLAL--------------- -----------GSPM-YSIITPNILRLESEETVVLEAHDAQ--GDVPVTVIVHD-FPGKK LVLSSEKTVLTPATNHMGNVTFMIPANR-EFKSEK-GRNKFVTVQATFGA-----QVVEK VVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLP-VGR--------TV-MVNIEN P-EGIPVKQ-DSLSSQNQFGILPLSWDIPELVNMGQWKIQAYYENSPQEV-FSAEFEVKE YVLPSFEVIVEPTEKFYYIYN-------EKGLEVTITARFLYGKKVEGTAFVIFGIQDGE QRIS-----LPESLKRILIEDGSGEVVLSRKVLLEGVQ-NPRAEDL--VGKSLYVSVTVI LHSGS---------------DMVQAERSGIPIVTSPYQIHFTK-TPKYFKPGMPFDLMVF VTNP-DGSPAYRVPVAV---QGEDT-----------------------VQSLTQGDGVAK LSINTHPSQ----KPLSITVRTKKQELSEA----------EQATSTMQALPYSTVGNSNN YLHLSVPRTEL----RPGE-TLNVNFLLRMDRA--HEAKIRYYTYLIMNKGRLLKAGRQV REPGQDLV-----------------------------VLPLSITTDFIPSFRLVAYYTLI GASGQREVVADSVWVDVKDSCVGSLVV------KSGQS-EDRQPVPGQQMTLKIEGDHGA RVVLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSS SGQQTAQRA--ELQCPQPA-ARRRR---SVLLTEKRMDKVGKYP-KELRKCCEDGMRE-- NPMRFSCQ---RRTRFIS-------LGE-ACKKVFLDCCNYITELRR------------- QHARAGHLGLARSDLDE----DIIAEEN---------IVSRSEFPESWLWN-VEDLKE-P ------------PKNGISTKLM-NIFLKDSITTWEILAVS--MSDKKGICVADPFEVTVM QDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVR-------VELLHNPAFCSLATTK RRHQQT---VTIPPKSSLSVPYVIVPLKT---GLQEVEVKAAVYHH-----------FIS DGVRKSLKVVPEGIRMNKTVAVRTLDPERL-------------------------GREGV QKEDIPPADL-SDQVPDTESETRILLQG-TPVAQMTE----DAVDAERLKHLIVTPSGCG EQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSA--FAAF VK--RAPSTWLTAYVVKVFSLAVNL--IAIDSQVLCGAVKWLILEKQ-KPDGVFQEDAPV ---IHQEMIGGLRN-NNEKDMALTAFVLISLQEAKD--ICEEQVNSLPGSITKAGDFLE- -ANYMNLQRSYTVAIAGYALAQMGR--LKGPLLNKFL----------------------- TTAKDKNRWEDPGKQLY---------NVEATSYALLALLQLKD--------FDFVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D VPDHKELNLDVSLQLPSRSS----KITHRIHWESASLLRS-----EET--KENEGFTVTA EGKGQGTLS-----------------------------------------VVTMYHAKAK DQL-T-CNKFDLKVTIKP----------------APET---------------------- ------------------------------------------------------EKRPQD AKNTMILEICTRYRG-DQDATMSILDISMMTGFA------PDTDDLKQLASGVDRYISKY ELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQ-YFNVELIQPGAVKVYAYYNLAESCTR FYHPEKEDGKLNK--------LCRDE-----LCRCAEEN-----CFIQKSD--------- -----------------DKVTLEERLDKACE-------PGVDYVYKTRLVKVQLSNDFD- ---------------EYIMAIEQTIKSGS-DEV-QVGQQRTFISPIKCREALK------- -------------LEEKKHYLMWGLSSDFWG--EKPN-----------------LSYIIG KDTWVEHWPEEDECQDEEN--------QQQCQDLGAFTESMVV----------------- -------FGCPN------- >XP_018871079.1 complement C3 [Gorilla gorilla gorilla] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GP--TSGPS-L-LLLLLTHLPLAL--------------- -----------GSPM-YSIITPNILRLESEETVVLEAHDAQ--GDVPVIVTVHD-FPGKK LVLSSEKTVLTPATNHMGNVTFTIPANR-EFKSEK-GRNKFVTVQATFGA-----QVVEK VVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLP-VGR--------TV-MVNIEN P-EGIPVKQ-DSLSSQNQFGILPLSWDIPELVNMGQWKIRAYYENSPQQV-FSAEFEVKE YVLPSFEVIVEPTEKFYYIYN-------EKGLEVTITARFLYGKKVEGTAFVIFGIQDGE QRIS-----LPESLKRIPIEDGSGEVVLSRKVLLDGVQ-NPRAEDL--VGKSLYVSVTVI LHSGS---------------DMVQAERSGIPIVTSPYQIHFTK-TPKYFKPGMPFDLMVF VTNP-DGSPAYRVPVAV---QGKDT-----------------------VQSLTQGDGVAK LSINTHPSQ----KPLSITVRTKKQELSEA----------EQATRTMQALPYSTVGNSNN YLHLSVPRTEL----RPGE-TLNVNFLLRMDRA--HEAKIRYYTYLIMNKGRLLKAGRQM REPGQDLV-----------------------------VLPLSITTDFIPSFRLVAYYTLI GASGQREVVADSVWVDVKDSCVGSLVV------KSGQS-EDRQPVPGQQMTLKIEGDHGA RVVLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSS SGQQTAQRA--ELQCPQPA-ARRRR---SVQLTEKRMDKVGKYP-KELRKCCEDGMRE-- NPMRFSCQ---RRTRFIS-------LGE-ACKKVFLDCCNYITELRR------------- QHARASHLGLARSNLDE----DIIAEEN---------IVSRSEFPESWLWN-VEDLKE-P ------------PKNGISTKLM-NIFLKDSITTWEILAVS--MSDKKGICVADPFEVTVM QDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVR-------VELLHNPAFCSLATTK RRHQQT---VTIPPKSSLSVPYVIVPLKT---GLQEVEVKAAVYHH-----------FIS DGVRKSLKVVPEGFRMNKTVAVRTLDPERL-------------------------GREGV QKEDIPPADL-SDQVPDTESETRILLQG-TPVAQMTE----DAVDAERLKHLIVTPSGCG EQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQAALELIKKGYTQQLAFRQPSSA--FAAF VK--RAPSTWLTAYVVKVFSLAVNL--IAIDSQVLCGAVKWLILEKQ-KPDGVFQEDAPV ---IHQEMIGGLRN-NNEKDMALTAFVLISLQEAKD--ICEEQVNSLPGSITKAGDFLE- -ANYMNLQRSYTVAIAGYALAQMGR--LKGPLLNKFL----------------------- TTAKDKNRWEDPGKQLY---------NVEATSYALLALLQLKD--------FDFVPPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D VPDHKELNLDVSLQLPSRSS----KITHRIHWESASLLRS-----EET--KENEGFTVTA EGKGQGTLS-----------------------------------------VVTMYHAKAK DQL-T-CNKFDLKVTIKP----------------APET---------------------- ------------------------------------------------------EKRPQD AKNTMILEICTRYRG-DQDATMSILDISMMTGFA------PDTDDLKQLANGVDRYISKY ELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQ-YFNVELIQPGAVKVYAYYNLAESCTR FYHPEKEDGKLNK--------LCRDE-----LCRCAEEN-----CFIQKSD--------- -----------------DKVTLEERLDKACE-------PGVDYVYKTRLVKVQLSNDFD- ---------------EYIMAIEQTIKSGS-DEV-QVGQQRTFISPIKCREALK------- -------------LEEKKHYLMWGLSSDFWG--EKPN-----------------LSYIIG KDTWVEHWPEEEECQDEEN--------QKQCQDLGAFTESMVV----------------- -------FGCPN------- >XP_021136840.1 complement C3 [Columba livia] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------EMRSR--------------- -----------WSHFWVTMVAPAVLRLDTEEQVVLEAPGLT--VATEATLLVQD-FPGKR QVLYQVRVPINPAQGMLATATIKVSAK--ALPPAQ-G-KRFVSVTARVAQ-----VTLEK VLLVSLQSGHIFVQTDKPIYTPSSTVLCRLFALDHRMEP-APK--------TV-VVEFKT P-DNIIVKQ-VPVSSPMKTGIFSLNHYLPEVVSLGTWTIMAKFEDSPEQV-FSTQFEVKE YVLPSFEVLLEPEEKFLYIDR-------QEDFRVTVTARYLYGKHLQGSAFVLFGVMVDD EKKS-----IPQSLQRIQVTDGDGEAILSMADLRQ--R-FKNPQEL--VGHSLYVSVTVL TDSGS---------------DMVETQRSGIHIVTSPYTIHFTH-TPKYFKPGMPFDLTVY VTNP-DGSPAPRVTVKA---DGFQG------------------------IVSTQRDGTAK LVLNMPANK----DTVPITVRTDQPGLPAE----------RQASRQMTAEAYRSQGSSGN FLHLAVGATEV----KPGD-NLVVNFHLKSSSN-AVRDAVRFFTYLIMSKGRIVRVGRQA HEAGQSLV-----------------------------TMSLPVTAELIPSFRIVAYYYV- ---MPSEIVADSVWVDVKDTCMGSLVV------KGASEADNRVHEPGTPMRLRIEGDHKA HVGLVAVDKGVFVLNK--KHKITQAKVWDTVEKSDIGCTAGSGRDNVGVFADAGLSIVTS EKVTTPQRA--EVQCPQPA-KRKRR---SLQLMEYKGTKAAEYTDKAQRKCCEDGMKD-- NPMGHSCE---RRATYIQ-------DGE-TCVQAFLTCCNYIKGIRE------------- QKQRELHLQLARSEVDD----GFLDDDD---------IPSRSLFPESWLWQ-EETLTEPP ------------NDLGISGKTL-PIYLKDSITTWEVLAVS--LSPTKGLCVADPYEITVM KEFFIDLRLPYSVVRNEQVEIRAVLYNYWT-HEITVR-------VELVHNPAICSASTSK TRYQQI---LKLKPQSSWAVPFVIVPLQL---GQHDVEVKAAVRGS-----------FVA DGVKKKLKVVPEGIRLEKTVKIVELDPKTK-------------------------GINGV QEERVRAANL-SDIVPNTESETKVSIQG-NPVSILVE----KAIDGDKLKHLIVTPAGCG EQNMIGMTPTVIATHYLDSTQQWESFGIDRRAEAINLIKKGYTQQLAFRKPDNS--YAAF KD--RPSSTWLTAYVAKVFSLAITL--VDIEPEVVCGAVKWLILEKQ-KPDGIFQEDAPV ---IHKEMVGGYQG--AEPEVSLTAFVLIALQESRE--ICKDRVNSLERSITKAAQYLT- -KRYQSLARPYTVALTSYALALTGH--LKSEKV--LM----------------------- KFSKGGKSWEERNARTY---------NMEGTSYALLALLQMEK--------AELTGPVAR WLAQQNYFGGGYGST-------------------------QATMLVFQALAQYQL----A SPRQLELNLDVSLLLPRRAK----PVTYRIENRNALVARS-----AET--KLNEDFTVKA EGTGKGTMT-----------------------------------------VVTVYNAKVP EKD-NKCDNFDLRVQVED----------------VKAG---------------------- -------------------------------------------------------KEEDG VVRSVKITICTRHLD-NVDATMSILDVSMLTGFS------PDLQDLKRLTEGVDRYISKF EIDKALAERSNLVIYLDKISHKAEECFAFKAHQ-RFRVGLIQPAAVTVYSYYKIDDRCTR FYHPDKDGGQLSK--------ICYGD-----ICRCAEEN-----CFVRHKDD-------- -----------------VAVTVNQRIERACE-------AGVDYVYKVKLVATEQSPSHD- ---------------NYIMTVLSVIKTGT-DED-PAGGNRTFVSHRQCRDALQ------- -------------LRLGQEYLVWGLASDMWV--TNGR-----------------FSYLVG KDTWLELWPSEDACQEPDL--------MSLCQDLLDFAEAMTM----------------- -------FGCPS------- >XP_006023407.1 complement C3 [Alligator sinensis] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------EGSICYL-AAVLLFCFPAVV--------------- -----------HSQL-YSLIIPNVLRVESEEKVVVEANGLS--AVTEVTITVHD-FPFKR QVLYLIKANLNPDEGMLTTATIKISSNQ-VKKDSR-D-NQYVLIQAKIKD-----VTLEK VVLLSFHSGYIFVQTDKTIYTPGSTVLCRIFAMGHKMEP-LFK--------TV-IVEFET P-EGIIVKQ-SPVFSPMKTGIYSLNYNLPEIVNLGTWKVVAKFQDSPLQN-FSTQFEVKE YVLPSFEVILEPSEKFLYIDD-------DKDFRVSITARYLYGKKLEGTAFVLFGVKMEN EKRS-----IPQSLKRIQIQDGDGEAVLTRGMLQA--R-FPNLQEL--VGHTLYISVTVL TESGS---------------DMVEAERTGIHIVTSPYQIHFTK-TPKYFKPGMPFELMVY VTNP-DGSPAPRVPVKA---DNFQG------------------------TVSTQGNGMAK LILNMPGDK----ERVKVTVRTVHENLKPE---------NRQASQSMVAEAYKTQGGTKN YLHLAVTASEL----KSGD-NLPVNFHLKTDNI-NILNGLKHFSYLILNKGKIVQAGRQL RQAGQNLV-----------------------------SMPLPITPDLVPSFRIVAYYQV- ---GSSEMVADSVWVDVKDTCMGTLVV------KGATEADNRIHEPGTPMKIKVEGDYKA HVGLVAVDKGVYVLNK--KFKFTQSKIWDTVEKSDIGCTAGGGRDNLGVFADAGLALQTN T-ISTPQRT--EFDCPQPA-SRKRR---SVQLIEHKASKVANYHDQKLKKCCEDGMYE-- NPMGHSCD---KRAVYIQ-------DTK-ECVAAFLDCCKYIKTIRD------------- EKQRELVLELARSEVDE----GFLSDDD---------ITSRSLFPESWLWQ-VEQLTEQP ------------NNMGISTKTI-PVFLKDSITTWEVLAVS--LSENKGICVANPYEITVM KDFFIDLRLPYSVVRNEQVEIRAILYNYWD-KNIKVR-------VELIHNPAFCSASTSK QRYRQI---YDLPRLSSLAVPLVIVPLEL---GLHDVEVKAAVWGQ-----------FVA DGVKKKLKVVPEGMRMTKTVKSVTLEPSVK-------------------------GLGGV QVEQVTAADI-EDIVPNTESETRVSVQG-NPVTTIIE----KSIDGANVKHLIVTPSGCG EQNMIGMTPTVIATHYLDSTNQWDKVGVDRRNEAIRLINQGYTQQLVYKKGDFS--YSAF QN--RESSTWLTAYVAKVFAMATSL--VGIEHQVLCGAVKWLILEKQ-KPDGVFQEDGPV ---IHGEMVGGYKG--AEPEVSLTAFVLIALHESKD--ICKDHINSLEGSINKAAEFLS- -KKYMFLKRPYTIALTSYALALVEK--LNSEKV--LM----------------------- KCAKGANHWEEKGARTF---------NIEGTSYGLLALLKMKK--------FELTGPIVR WLTEQKYYGGGYGST-------------------------QATILVFQALSQYQM----D IPQQSELQLDVSILLPRRAT----PVKIRIENSNAFLSRS-----AET--KWNENFTVRA EGTGQGTLT-----------------------------------------VVTVYNAKIK EDE-SKCKKFYLSVSVEN----------------IPRP---------------------- -------------------------------------------------------KNKEG ILRSVKINICTRFLG-EVDATMSIIDVSMLTGFS------PDTDDLKRLSQGVDRYISKF EMDKAPSERASLIIYLDKVSHTEEECLSFKAHQ-FFEVGLIQPASVTVYDYYTIDDRCTK FYHPSKQSGLLSK--------ICHGD-----VCRCAEEN-----CFMQHKMD-------- -----------------SPVTLDKRIEDACE-------PGVDYVYKTRLVETEESSSYD- ---------------NYIMEILTIIKAGT-DEN-PVGQRRKFISHVKCRESLN------- -------------LEQNKDYLIWGLSSDLWT--MKNE-----------------LSYIIS KDTWIEKWPNEEECQEPDF--------QKLCQEFQEFSEAMTM----------------- -------FGCPT------- >XP_006265663.2 PREDICTED: complement C3 [Alligator mississippiensis] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------EGSICYL-AAVLLFCFPAVV--------------- -----------HSQL-YSLITPNVLRVESEEKVVVEANGLN--AATEVTITVHD-FPFKR QVLYLIKANLNPDEGMLTTATIKISSNQ-VKKDSR-D-NQYVLIQAKIKD-----VTLEK VVLLSFHSGYIFVQTDKTIYTPGSTVLCRIFAMGHKMEP-LFK--------TV-IVEFET P-EGIIVKQ-SPVFSPMKTGIYSLNYNLPEIVNLGTWKVVAKFQDSPLQN-FSTQFEVKE YVLPSFEVILEPSEKFLYIDD-------VKDFRVSITARYLYGKKLEGTAFVLFGVKMEN EKRS-----IPQSLKRIQIQDGDGEAVLTRGMLQA--R-FPNLQEL--VGHTLYISVTVL TESGS---------------DMVEAERTGIHIVTSPYQIHFTK-TPKYFKPGMPFELMVY VTNP-DGSPAPRVPVKA---DDFQG------------------------TVSTQGNGMAK LILNMPGDK----ERVKVTVRTVHENLKPE---------NRQASQSMVAEAYKTQGGTKN YLHLAVTASEL----KSGD-NLPVNFHLKTDNI-NILNGLKHFSYLILNKGKIVQAGRQL RQAGQNLV-----------------------------SMPLPITPDLVPSFRIVAYYQV- ---GSSEIVADSVWVDVKDTCMGTLVV------KGATEADNRIHEPGTPMKIKVEGDYKA HVGLVAVDKGVYVLNK--KFKFTQSKIWDTVEKSDIGCTAGGGRDNLGVFVDAGLALQTN T-ISTPQRT--EFDCPQPA-SRKRR---SVQLIEHKASKVANYHDQKLKKCCEDGMYE-- NPMGHSCD---KRAMYIQ-------DTK-ECVAAFLDCCKYIKTIRD------------- EKQRELVLELARSEVDE----GFLSDDD---------ITSRSLFPESWLWQ-VEQLTEQP ------------NNMGISTKTI-PVFLKDSITTWEVLAVS--LSENKGICVADPYEITVM KDFFIDLRLPYSVVRNEQVEIRAILYNYWD-KNIKVR-------VELIHNPAFCSASTSK QRYRQI---YDLPRLSSLAVPLVIVPLEL---GLHDVEVKAAVWGQ-----------FVA DGVKKKLKVVPEGMRMTKTVKSVTLEPSVK-------------------------GLGGV QVEQVTAADI-EDIVPNTESETRVSVQG-NPVTTIIE----KSIDGANVKHLIVTPSGCG EQNMIGMTPTVIATHYLDSTNQWDKVGVDRRNEAIRLINQGYTQQLVYKKGDFS--YSAF QN--RESSTWLTAYVAKVFAMATSL--VGIEHQVLCGAVKWLILEKQ-KPDGVFQEDGPV ---IHGEMVGGYKG--AEPEVSLTAFVLIALHESKD--ICKDHINSLEGSINKAAEFLS- -KKYMFLKRPYTIALTSYALALVEK--LNSEKV--LM----------------------- KCAKGANHWEEKGARTF---------NIEGTSYGLLALLKMKK--------FELTGPIVR WLTVQKYYGGGYGST-------------------------QATILVFQALAQYQM----D IPQQSELQLDVSILLPRRAT----PVKIRIENSNAFLSRS-----AET--KWNENFTVRA EGTGQGTLT-----------------------------------------VVTVYNAKIK EDE-SECKKFDLRVSVEN----------------IPRP---------------------- -------------------------------------------------------KNKEG ILRSVKINICTRFLG-EVDATMSIIDVSMLTGFS------PDTDDLKRLSQGVDRYISKF EMDKAPSERASLIIYLDKVSHTEEECLSFKAHQ-FFEVGLIQPASVTVYDYYTIDDRCTK FYHPSKQSGLLSK--------ICHGD-----VCRCAEEN-----CFMQHKMD-------- -----------------SPVTLDKRIEDACE-------PGVDYVYKTRLVDTEESSGYD- ---------------NYIMEILTIIKAGT-DEN-PVGQRRKFISHVKCRESLN------- -------------LEQNKDYLIWGLSSDLWT--MKNE-----------------LSYIIS KDTWIEKWPNEEECQEPDF--------QKLCQEFQEFSEAMTM----------------- -------FGCPT------- >XP_020772460.1 complement C3 [Odocoileus virginianus texanus] M----------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------RP--TSGPSLL-LLLLLASLPMAL--------------- -----------GSPM-YSMITPNILRLESEETVVLEAHGGQ--GDIPVSVTVHD-FPAKR QVLSNENTQLNNGNGYLATVTIKIPASK-ELKSDK-G-HKFVTILATFGG-----VQVEK VVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDHKLLP-VGQ--------TV-IVSIET P-DGIPVKR-DSQSSHNQFGILALSWNIPELVNMGVWKIKAHYEDSPQQV-FSADFEVKE YVLPSFEVQLEPEEKFYYVDD-------PDGLKINIIARFLYGEHVDGTAFVIFGVQDGD RRIS-----LTHSLTRVPIIDGNGEAILRRQVLLNGVQ-PSRADAL--VGKSIYVSATVI LQSGS---------------DMVEAERTGIPIVTSPYQIHFTK-TPKFFKPAMPFDLMVY VTNP-DGSPARHIPVVT---QGSNV------------------------QSLTQDDGVAK LSINTQNKR----DPLTITVRTKKDNIPED----------RQATKTMQALPYNTQGNSNN YLHLSVTRVEL----KPGE-TLNVNFHLRTDPG--QQAKIRYYTYMIMNKGKLLKVGRQD REPGQDLV-----------------------------VLPLTITSDFIPSFRLVAYYTLI NANGQREVVADSVWVDVKDSCMGTLVV------KSGGK-EEKHHRPGQQITLKIEADQGA RVGLVAVDKGVFVLNK--KNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTS QGLETKQRA--DPLCPQPA-VRRRR---SVQLMEKRMDKVGQYS-GDLRKCCEDGMRD-- NPMKFPCQ---RRAQFIL-------QGD-ACVKAFLDCCEYIAQLRQ------------- QHNRDSALELARSDLDD----EIIPEED---------IISRSQFPESWLWTIIEDFKQ-A ------------DKNGISTKLT-NVFLKDSITTWEILAVS--LSDKKGICVADPYEVTVM QDFFIDLRLPYSVVRNEQVEIRAVLYNYREAEDLKVR-------VELLYNPAFCSLATAK KRHQQT---LVIPARSSLAVPYVIVPLKV---GLHEVEVKAAVYNH-----------FIS DGVKKTLKVVPEGIRVNKTVAIQTLNPEHL-------------------------GQGGV QRVEVPAADL-SDQVPDTESETKILLQG-TPVAQMTE----DAIDGERLKHLIQTPSGCG EQNMIGMTPTVIAVHYLDSTEQWEKFGLEKRQQSLELIRKGYTQQLAFRQKNSA--YAAF LN--RPASTWLTAYVVKVFALSANL--IAIDSKDLCETVKWLILEKQ-KPDGIFQEDGPV ---IHQEMIGGFKD-AREKDVSLTAFVLIALHEAKD--ICEAQVNSLGRSINKAGDFLE- -NHYRELRRPYTVAIAAYALALLGK--LEDDRLTKFL----------------------- NTAKEKNRWEEPNQKLY---------NVEATSYALLALLARKD--------YDTVAPVVR WLNEQRYYGGGYGST-------------------------QATFMVFQALAQYQK----D VPDHKDLNLDVSIQLPSRNS----LVKHRILWESASLLRS-----EET--KENERFTVRA EGKGQGTLS-----------------------------------------VVTVYHAKLK GKV-S-CKKFDLQVSIHP----------------APEP---------------------- ------------------------------------------------------VKKPQD AKGSMILDICTRYLG-DQDATMSILDISMMTGFS------PDIDDLKLLSSGVDRYISKY EMNKD-SNKNTLIIYLDKVSHTVEDCLSFKVHQ-YFNVGLIQPGAVKVYSYYNLDETCIR FYHPDKEDGMLSK--------LCHKD-----TCRCAEEN-----CFMHHPD--------- -----------------EEITLDGRLDKACE-------PGVDYVYKTRLTRKKLEDDFD- ---------------EYIMVIEQIIKSGS-DEV-QVNQERKFISHIKCREALK------- -------------LKEGAHYLVWGVSSDLWG--EKPN-----------------ISYIVG KDTWVELWPDAEECQDEEN--------QKQCEELANFTENMVV----------------- -------FGCPN-------
BMGE Cleaned alignment of selected proteins >NP_000055.2 complement C3 preproprotein [Homo sapiens] TSGPS-LLLLLLTLPLALYSIITPNILRLESEETMVLEAHDAGDVPVTVTVHDFPGKKLVLSVLTPATNHMGVTFTIPAEFKSENKFVTVQATFGTVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNMVNIENPEGIPVKQDSLSSQNLGVLPLSDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVLTQGDGVAKLSINTHPLSITVRTKEQATRTMQALPYSTVGNSNNYLHLSVLTLNVNFLLRMDRAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLGASGQREVVADSVWVDVKDSCVGSLVVTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVQLTEKRMDKVGKYPELRKCCEDGMRENPMRFSCQRRTRFISACKKVFLDCCNYILGLARSNLDEDIIAEENIVSRSEFPESWLWNVEDLKPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRVELLHNPAFCSLATTKRRHTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERGREGVQKDIPPADLSDQVPDTESETRILLQGDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVRAPSTWLTAYVVKVFSLAVNLVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNEKDMALTAFVLISLQEAKDQVNSLPGSITKAGDFLENLQRSYTVAIAGYALAQMGRLLNKFLNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQQELNLDVSLQLPSRSTHRIHESASLLRSKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLCNKFDLKVTTMILEICTRYRGQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENTLEERLDKACEPGVDYVYKTRLVAIEQTIKSGSVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGLSYIIGKDTWVEHWPEEDECQDEENQCQDLGAFTFGCPN >tr|A5PMP6|A5PMP6_DANRE Complement component c3b, tandem duplicate 1 OS=Danio rerio OX=7955 GN=c3b.1 PE=4 SV=1 -----LLQLLLWALLCQIFSLLAPAKIRPGTKQNILVEGHNLQVVEVTVVVYDYPNSQTALSFLNSDNNYSVQTLEINPLLPDGKKYVKLVAQFSNAEKVMAVSFRSGHIFIQTDKPIYNPGDKVRFRAFVSDSLEIQNPDGIAVHGGRVKA--DGVFSDISLSTVVKYALRI------------------VQLCLLPAFNVTLTPKTSHLSLD-EKLEVEITARYLYGAQVKGVAYVLFGIEINGEKKRLTSMKQIDDVLNG-GSVSLTMEEIKR--ALGSTLYVKASVLTSSGSDLVEAEKSGIKIVKSPYMLTIKDTPKYYKPGLPLAMTVIVSNHDGSPTPNIPVKVISVHSGTINIHINMPSQILKVETVQQAIQEVYVKPYSTFSGHDNFLHVSVGSVSVQMYIKSSLALVEHLTYIVLNKGKIIQAGRVNVK-GQDVTSVHLLITTEMLPAFRFVAYYVLPWQHRAEVVADSVFVDVEDRCVGSLNVKFQVKGDVGAKVSLVAVDNAIFLLS-KNRLTQKKVWEVVDQADMGCTAGGGKDNMGVFSDAGLMFHSSTGGSTDSKED--CSSKTKRRRRSAAKLQLRDQLEKAYSLLQRCCVDGMKEIPMPYSCYRRSLYITSFFFVRDRVLQSMEEAASVFEEDDLSDLEDIYVRSKFFESWLWTDIRLPKSDGLAVFPVDTVLPDSITQWGFLAVSASPEKGVCVAEPYNVRVWKPFFIDLRLPHSVSRNEQVEIKAVIHNYKVILEKTEDMCSVAYTGQ-HTVAAGSSKLITYTIIPLKTGELPLQVTAVAMGQDAVKKNLRVVVEGIQTLKVR-SFVLNPSEGSAGQQLQVKKMQLDAVVPKSVPETFVNVRGNSIKEDSLAALIRMPGGCVEQNLARITLPLIAAHYLDRSADWEIVGISRREEAIKYIQRGYENQLNYKKSDDSYPPYAEGTSTWITAYVVKVFSMAHSFHLCGPLLYLLKNKQGYDGTFQEDNPVYDTSMTGAMRGSEYKASLTAFVLIALAEAQDQEVNIRDKSRQAAGYLTRLTRPYTAAIACYALAVSNNMLLKFASHWPDSNNYFFTLEATGYALLALIKSGHMEEAEAPFRWLNEHRGIGGGYGSTQSTMVVLQALSEYLSDLNLLVQLSVPGRSRWTFNNLAYVARSPLDQEFSVAASGNGKGVLEVVTVYHQLPDVYECNGFQLDVSSFRLNVNVRALERQVRMVILDIGLPTGFEPENSDLELLTNSVDRYINNFQVVDNLSDRGSLIIHLFKVSNAEMISFRLNQKFKVGLLQPSTVKVYQYYNKDKSCSRFYSPPEDKQQLDQICEGDVCRCSQGDGKEQRNAAVCN-GLHHAYRVKLIEIVQVIKEGTEKERRMFLSHASCRTRLNLKEGQEYLVIGPITDVWNYVYTLGKETWVERWPDESECGSTL-KCDELKSFADGCQA >tr|B8JKW4|B8JKW4_DANRE Complement component c3a, duplicate 1 OS=Danio rerio OX=7955 GN=c3a.1 PE=1 SV=1 -VKLLFLSAVLLSALLTLYVLSAPNLLRVGSSENVFVEAQDYNAFEVKITVKNHPKKDKQILNLNAQNNFQITDIKIPDLFSDDKQYVYLQAIFPDLEKVVLLSFQSGYIFVQTDKPIYTPSSTVQYRTLSLTTVEIMNPQNITVSSDKVYP--KGMKSGKAIPEVASLGIWKVVTRFANTPQKTFTAEFEVKEYVLPTFEVKLQPSKLFYYVG-ESLTVDIEAKYLFGKQVEGNAFVMFGVMDGETKTGITGSLQKIQILKGVGTAELTKQMI-E--TVGQSIYVSVSLLTESGSEMVEAERRGIRIVTSPYTINFKKTAQFFKPGMPFDVSIYVTNPDETPAQNVIVEVQTKANGIAKVTVNTQTQEITAQTKEQAVKKMTAHAYVPKGGSKNYLHIGIDQMKVNLNTGQSPVKDQDYTFMILSKGQIVKIDRFKRQ-GQALITLSQPVTKEMVPSFRFVAYYHV---GANEVVSDSVWVDVKDTCMGKLKLKLQISGDPGARVGLVVVDKAVHVLN-KNRLTQTKIWDVIEKHDTGCTAGGGRDVMGVFSDAGLMFESNTAGGTDTRLNPECPDPPKRRRRSENLRTITATLAGQYAGQRQCCIDGMKDNKLGYTCERRATYIGECVKAFLHCCDEMMILARSDDDDYYTDSEEIVSRTQFPESWLWEEIDLC-NCPASAMEKAMYLKDSITTWQVLAVSMSPTLGICVAEPEEIVVFKSLFIDLKMPYSAVRGEQLEIKAIIHNYTVEFMESADVCSLASKKGKYTIPKESSLSVPYVIIPMTLGNHMIEVKAAAVYTDGVRKGLKVVSEGVLFPLQRPNVELNPVK---GDSPIVRADIPADRVPGTPAHTHISITGQAISGSFMGQLIVQPHGCGEQNMIFMTLPVIATHYLDSTNQWEAIGMKRRDEAIGHIKTGYNRQQAYRKPDGSYAAWIRPSSTWLTAYVAKIFAMANDLVLCSALKWLVLNRQLPDGSFEEKAAVVHGEMVGDVQGRDAEASLTAFVTIAMQEGREIVGSLPESIRKAVSFLEKLTNPYAVALTSYAMAGADKVLMKFSTYWNVPGQQYHTREATSYAVLALVKARDFNAAGEAVHWLGSQHYSYGGSGTTQATIMVFQAVAEYRQNFNLEVELAVEGRSRYTIKDNRHVSRSDINKDFNVTAKGTGKATLSVLTLYYARPVEKKCTLFDLSVKTFKLTMDFFYKNSPATMTILDIGIPTGFTVEYNDLEELTRGKEKYLEKFEMDKALSDRGSLILYLKMVSNSERIAFRMHKMLNVGLLQPAAVTIYEYYSPNARCTKYFHPERE-GVIYRLCKGDMCQCAEENKDEERNIKACESGMDYVYKVKVKEVEQVLKEGTEGQVKSFLGRPSCKESLGFVQGKSYLIMGKSTDLPKLQYILGEQTWIEYWPTSQESKSAEHRYIGITELEEGCAT >tr|F1QX13|F1QX13_DANRE Complement component c3a, duplicate 3 OS=Danio rerio OX=7955 GN=c3a.3 PE=1 SV=1 EVKLLFLSAVLLSALLTLYVLSAPNLLRVGSSENVFVEAQDYGPLNVRISVKNFPAKNVEMMTLTGA-KYQSTDIQIPGYFSDDKQYVYLQAHFPSLEKVVMVSFQSGYLFVQTDKPIYTPGSNVHYRIFSMTTVDITNPQGITVASDTIFA--KGVKSSINIPEVTSLGMWKVVTRYANTPQKTFTAEFEVKEYVLPTFEVKLKTSKSFYYVGDDSLTVDMEAKYLFGKKMDGNAFVVFGVMDGAMKTSIVNSLQKVQVFNGVGTAELTREMITK--TVGKSIYVSVNLLTESGSEMVEAEKRGIQIVTSPYTIHYKRTSQFFKPGMPLGVSVYVTNPDETPAEDVEVEVKTKANGIAKVTVNTKTLKITATTRQQADKTMIAQAYKTNLGSKNYLHINIEQMTVYLNTGESPVKDQDFTYMILSKGQIVLAERFKRQ-GQTLVSLSLPVTKDMVPSFRFVAYYHV---GKDEVVSDSVWVDVKDTCMGKLKVNLQISGDFGARVGLVVVDKAVQVLN-KNRLTQSKIWDVIEKHDTGCTGGGGKDSMGVFSDAGLMFESDPAGGTNTRTEPKCPAPPKRKRRSESLQTITTTLAGQYTKIRPCCYDGMRNNRIGYTCERRASYVIECVKAFLHCCKEVLILARKDDEEDYEDYDDITSRKQFPESWLWEEFDLC-KCSKPSKNKVTYLKDSITTWQILAISLSPTHGICVAEPEEIVVFKSFFIDLKVPYSAVRGEQVEIKAIIHNYTVEFLETAGVCSAASKKGKYNVDKDSSIAVSFVIVPMTLESQHIEVKASI-YTDGVRKTLKVVSEGVLTKFQSQKLELNPAK---GEQPLLRAGIPGDQVPGTPVHSYITVTGHAINGSFMGELIKRPGGCGEQNMAKMTLPVVATHYLDNTNQWESVGIDRRKVAINHIKTGYDGQLKYRKPDGSYAIWITPSSTWLTAYVAKVFAMANDFVICSALKWLVMHKQLPDGSFKEDAPVYDKSIMGGIEGQNTDVSLTAFVLIAMQEGKETVGSLHESMRKAVAFLKKLTNPYAVALTSYALANADSILMMHSRFWNVPERQYYSIEATAYAVLALVKAKDYDTAGEAVHWLAKQKSSHGGYDTTQVTIMVFQAVAEYHNNFDLNVELVVPGRRRWTIQSNVHLARSDLNKDFTVIAKGTGSAILSVLTLYYARPFEKKCTFFDLSVKTYNFILDFFYKNNDATMTILDIGLPTGFDIDEADLKQLSTGKERYIQKYEKNKVLSERGSLIIYLNKVSHSEKLVFRMHKTFNVALLQPASVTIYEYYSPDARCKKYYHPEREDSALYRLCKGDLCVCAEENDESKRLIKACEPHLDYIYKAKLVKVEKTVKEGTEGKVKQFLARPSCRVSLGLVEGKSYLIMGNSVDLPTLQYVIGEQTWIEYWPTSDESKSAEHRYIGMTAVEGGCLT >XP_024207219.1 complement C3 [Pan troglodytes] TSGPS-LLLLLLTLPLALYSIITPNILRLESEETVVLEAHDAGDVPVTVIVHDFPGKKLVLSVLTPATNHMGVTFMIPAEFKSENKFVTVQATFGAVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNMVNIENPEGIPVKQDSLSSQNFGILPLSDIPELVNMGQWKIQAYYENSPQEVFSAEFEVKEYVLPSFEVIVEPTEKFYYIYNKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGLGEVVLSRKVLLEGVQVGKSLYVSVTVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVLTQGDGVAKLSINTHPLSITVRTKEQATSTMQALPYSTVGNSNNYLHLSVPTLNVNFLLRMDRAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLGASGQREVVADSVWVDVKDSCVGSLVVTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVLLTEKRMDKVGKYPELRKCCEDGMRENPMRFSCQRRTRFISACKKVFLDCCNYILGLARSDLDEDIIAEENIVSRSEFPESWLWNVEDLKPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRVELLHNPAFCSLATTKRRHTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERGREGVQKDIPPADLSDQVPDTESETRILLQGDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVRAPSTWLTAYVVKVFSLAVNLVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNEKDMALTAFVLISLQEAKDQVNSLPGSITKAGDFLENLQRSYTVAIAGYALAQMGRLLNKFLNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKELNLDVSLQLPSRSTHRIHESASLLRSKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLCNKFDLKVTTMILEICTRYRGQDATMSILDISMMTGFAPDTDDLKQLASGVDRYISKYELDKAFSDRNTLIIYLDKVSHDDCLAFKVHQYFNVELIQPGAVKVYAYYNLAESCTRFYHPEKEDGKLNKLCRDELCRCAEENTLEERLDKACEPGVDYVYKTRLVAIEQTIKSGSVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGLSYIIGKDTWVEHWPEEDECQDEENQCQDLGAFTFGCPN >XP_043322320.1 complement C3 [Cervus canadensis] TSGPSLLLLLLLALPMALYSMITPNILRLESEETVVLEAHGGGNIPVSVTVHDFPAKKQVLSQLNNDNGYLAVTIKIPAELKSDHKFVTVLATFGDVEKVVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDIVSIETPDGIPVKRDSQSSHNFGILALSNIPELVNMGVWKIKAHYEDSPQQVFSADFEVKEYVLPSFEVQLEPEEKFYYIDDDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILRRQVLLNGVQVGKSIYVSATVILQSGSDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTLTQDDGVAKLSINTQPLTITVRTKRQATKTMQALPYNTQGNSNNYLHLSVPTLNVNFHLRTDPAKIRYYTYMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLNANGQREVVADSVWVDVKDSCMGTLVVTLKIEADQGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTSQGLETKQRADPLCPQPAVRRRRSVQLMEKRMDKVGQYSDLRKCCEDGMRDNPMKFPCQRRAQFILACVKAFLDCCGYILELARSDLDDEIIPEEDIISRSQFPESWLWTIEDFKDKNGISTKLTNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRVELLYNPAFCSLATAKKRHVIPARSSLAVPYVIVPLKVGLHEVEVKAAVFISDGVKKTLKVVPEGIRVNKTVAIRTLNPEHGQGGVQREVPAADLSDQVPDTESETKILLQGDAVDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQQALELIRKGYTQQLAFRQKNSAYAAFLRPASTWLTAYVVKVFALSANLDLCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFRDREKDVSLTAFVLIALHEAKDQVNSLGRSINKAGDFLEELRRPYTVAIAAYALALLGKRLTKFMNRWEEPNQKLYNVEATSYALLALLARKDYDTVHPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDLNLDVSIQLPSRNKHRILESASLLRSKENERFTVRAEGKGQGTLSVVTVYHAKLKGKVCKKFDLQVSSMILDICTRYLGQDATMSILDISMMTGFSPDIDDLKLLSSGVDRYISKYEMNKD-SNKNTLIIYLDKVSHEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCRCAEENTLDGRLDKACEPGVDYVYKTRLVVIEQIIKSGSVNQQRKFISHIKCREALKLKEGAHYLVWGVSSDLWGISYIIGKDTWVELWPDAEECQDEENQCEDLANFTFGCPN >XP_027825575.2 complement C3 [Ovis aries] TSGPSLLLLLLLALPMALYSMITPNILRLESEETVVLEAHGGGNIQVSVTVHDFPAKKQVLSQLNSNNGYLSVTIKIPAELKSDHKFVIVVATFGNVEKVVLISLQSGYLFIQTDKTIYTPGSSVLYRVFTVDFISIETPDGVLVKRDSLSSHNFGILALSNIPELVNMGVWKIKAHYEDSPQQVFSTEFEVKEYVLPSFEVQLEPEEKFYYVDDDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILKRQVLLNGVQVGKSIYVSATVILQSGSDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTLTQDDGVAKLSINTQPLTITVRTKRQATRTMQALPYNTQGNSNNYLHLSVPTLNVNFHLRTDPAKIRYYTYMIMNKGKLLKVGRQEREPGQDLVVLPLTITSDFIPSFRLVAYYTLNANGQREVVADSVWVDVKDSCMGTLVVTLKIEANQGSRVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLTFKTSQGLETQQRSDPQCPKPAARRRRSVQLMEKRMDKVGQYSDLRKCCEDGMRDNPMKFPCQRRAQFILACVKAFLDCCEYILELARSDLEDEIIPEEDIISRSQFPESWLWTIDDFKDKNGISTKLMNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRVELLYNPAFCSLATAKKRHTIPARSSVAVPYVIVPLKVGLHEVEVKAAVFISDGVKKTLKVVPEGIRVNKTVAIRTLNPEYGQDGVQREVPAADLSDQVPDTESETKILLQGDAIDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGMEKRQEALELIRKGYTQQLAFRQKSSAYAAFQRPPSTWLTAYVVKVFALSTNLDLCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFKDREKDVSLTAFVLIALHEAKDQVNSLGPSITKAGDFLEELRRPYTVAIAAYALALLGKRLTKFLNRWEEPNKKLYNVEATSYALLALLARKDFDTVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKELNLDVSIHLPSRNKHRILESASLLRSKENERFTVRAEGKGQGTLSVVTVYHAKLKGKVCKKFDLRVSSMILDICTKYLGQDATMSILDISMMTGFSPDIDDLKLLSTGVDRYISKYEMNRD-SNKNTLIIYLDKISHEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCRCAEENTLENRLDRACEPGVDYVYKTRLIVIEQIIKSGSVKQERKFISHIKCREALKLKEGAHYLVWGVSSDLWGISYIIGKDTWVELWPEAEECQDEENQCEDLASFTFGCPN >KAB0363358.1 hypothetical protein FD754_007514 [Muntiacus muntjak] TSGPSLLLLLLLALPMALYSMITPNILRLESEETVVLEAHGGGNIPVSVTVHDFPAKKQVLSQLNNDNGYLAVTIKIPAELKSDHKFVTVLATFGGVEKVVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDIVSIETPDGIPVKRDSQSSHNFGILALSNIPELVNMGVWKIKAHYEDSPQQVFSADFEVKEYVLPSFEVQLEPEEKFYYIDDDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILRRQVLLNGVQVGKSIYVSATVILQSGRDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTLTQDDGVAKLSINTQPLTITVRTKRQATKTMQALPYNTQGNSNNYLHLSVPTLNVNFHLRTDPAKIRYYTYMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLNANGQREVVADSVWVDVKDSCMGTLVVTLKIEADQGARVGLVAVDKGVFVLNKKNKLTQRKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTSQGLETKQRADPLCPQPAVRRRRSVQLMEKRMDKVGQYSDLRKCCEDGMRDNPMKFPCQRRAQFILACVKAFLDCCEYILELARSDLDDEIIPEEDIISRSQFPESWLWTIEDFKDKNGISMKLTNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRVELLYNPAFCSLATAKKRHVIPARSSLAVPYVIVPLKVGLHEVEVKAAVFISDGVKKTLKVVPEGIRVNKTVAIRTLNPEHGQDGVQREVPAADLSDQVPDTESETKILLQGDAVDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQQALDLIRKGYTQQLAFRQKNSAYAAFLRPASTWLTAYVVKVFALSANLDLCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFRDREKDVSLTAFVLIALHEAKDQVNSLGRSINKAGDFLEELRRPYTVAIAAYALALLGKRLTKFMNRWEEPNQKLYNVEATSYALLALLARKDYDTVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDLNLDVSIQLPSRNKHRILESASLLRSKENERFTVRAEGKGQGTLSVVTVYHAKLKGKVCKKFDLQVSSMILDICTRYLGQDATMSILDISMMTGFSPDIDDLKLLSSGVDRYISKYEMNKD-SNKNTLIIYLDKVSHEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCRCAEENTLNGRLDKACEPGVDYVYKTRLIVIEQIIKSGSVNQERKFISHIKCREALKLKEGAHYLVWGVSSDLWGISYIIGKDTWVELWPDAEECQDEENQCEDLANFTFGCPN >KAB0388260.1 hypothetical protein FD755_003216 [Muntiacus reevesi] TSGPSLLLLLLLALPMALYSMITPNILRLESEETVVLEAHGGGNIPVSVTVHDFPAKKQVLSQLNNDNGYLAVTIKIPAELKSDHKFVTVLATFGGVEKVVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDIVSIETPDGIPVKRDSQSSHNFGILALSNIPELVNMGVWKIKAHYEDSPQQVFSADFEVKEYVLPSFEVQLEPEEKFYYIDDDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILRRQVLLNGVQVGKSIYVSATVILQSGRDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTLTQDDGVAKLSINTQPLTITVRTKRQATKTMQALPYNTQGNSNNYLHLSVPTLNVNFHLRTDPAKIRYYTYMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLNANGQREVVADSVWVDVKDSCMGTLVVTLKIEADQGARVGLVAVDKGVFVLNKKNKLTQRKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTSQGLETKQRADPLCPQPAVRRRRSVQLMEKRMDKVGQYSDLRKCCEDGMRDNPMKFPCQRRAQFILACVKAFLDCCEYILELARSDLDDEIIPEEDIISRSQFPESWLWTIEDFKDKNGISTKLTNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRVELLYNPAFCSLATAKKRHVIPARSSLAVPYVIVPLKVGLHEVEVKAAVFISDGVKKTLKVVPEGIRVNKTVAIRTLNPEHGQDGVQREVPAADLSDQVPDTESETKILLQGDAVDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQQALELIRKGYTQQLAFRQKNSAYAAFLRPASTWLTAYVVKVFALSANLDLCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFRDREKDVSLTAFVLIALHEAKDQVNSLGRSINKAGDFLEELRRPYTVAIAAYALALLGKRFTKFMNRWEEPNQKLYNVEATSYALLALLARKDYDTVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDLNLDVSIQLPSRNKHRILESASLLRSKENERFTVRAEGKGQGTLSVVTVYHAKLKGKVCKKFDLQVSSMILDICTRYLGQDATMSILDISMMTGFSPDIDDLKLLSSGVDRYISKYEMNKD-SNKNTLIIYLDKVSHEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCRCAEENTLNGRLDKACEPGVDYVYKTRLIVIEQIIKSGSVNQERKFISHIKCREALKLKEGAHYLVWGVSSDLWGISYIIGKDTWVELWPDAEECQDEENQCEELANFTFGCPN >KAF4014700.1 hypothetical protein G4228_005895 [Cervus hanglu yarkandensis] ARDNPYLQLPQEDEEMQMYSMITPNILRLESEETVVLEAHGGGNIPVSVTVHDFPAKKQVLSQLNNDNGYLAVTIKIPAELKSDHKFVTVLATFGDVEKVVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDIVSIETPDGIPVKRDSQSSHNFGILALSNIPELVNMGVWKIKAHYEDSPQQVFSADFEVKEYVLPSFEVQLEPEEKFYYIDDDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILRRQVLLNGVQVGKSIYVSATVILQSGSDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTLTQDDGVAKLSINTQPLTITVRTKRQATKTMQALPYNTQGNSNNYLHLSVPTLNVNFHLRTDPAKIRYYTYMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLNANGQREVVADSVWVDVKDSCMGTLVVTLKIEADQGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTSQGLETKQRADPLCPQPAVRRRRSVQLMEKRMDKVGQYSDLRKCCEDGMRDNPMKFPCQRRAQFILACVKAFLDCCKYILELARSDLDDEIIPEEDIISRSQFPESWLWTIEDFKDKNGISTKLTNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRVELLYNPAFCSLATAKKRHVIPARSSLAVPYVIVPLKVGLHEVEVKAAVFISDGVKKTLKVVPEGIRVNKTVAIRTLNPEHGQGGVQREVPAADLSDQVPDTESETKILLQGDAVDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQQALELIRKGYTQQLAFRQKNSAYAAFLRPASTWLTAYVVKVFALSANLDLCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFRDREKDVSLTAFVLIALHEAKDQVNSLGRSINKAGDFLEELRRPYTVAIAAYALALLGKRLTKFMNRWEEPNQKLYNVEATSYALLALLARKDYDTVHPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDLNLDVSIQLPSRNKHRILESASLLRSKENERFTVRAEGKGQGTLSVVTVYHAKLKGKVCKKFDLQVSSMILDICTRYLGQDATMSILDISMMTGFSPDIDDLKLLSSGVDRYISKYEMNKD-SNKNTLIIYLDKVSHEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCRCAEENTLDGRLDKACEPGVDYVYKTRLVVIEQIIKSGSVNQQRKFISHIKCREALKLKEGAHYLVWGVSSDLWGISYIVGKDTWVELWPDAEECQDEENQCEDLANFTFGCPN >XP_023100060.1 complement C3-like [Felis catus] ASGPSLLLLLLLPLPLAPFSMITPNILRLENEETVLLEAHDLNNIAVAVTVHDFPVKKQVLSALTKDNNHMSVKIKIPAELTSEKKFVTIQADFGSVEKVVLVSFQSGYLFIQTDKPIYTPGSTVLYRIFTVDIVSIQTPDNILIKKDSLSSQNVGILSLSNIPELVNTGQWKIEAHYEDAPQQVFSAEFEVKEYVLPSFEVQVEPTEKFYYIDDQGLEVTITARFLYGKNVDGIAFVIFGVQDGDQRISLPQSLTRVQIDDGSGEARLERKVLLSGVQVGKSLYVSVTVILHSGSDMVEAERSGIPIVTSPYQIHFTKTSKFFKPGMPFDLMVFVTNPDGSPARNVPVETLTQADGVAKLIINTPPLPITVITRRQATSSMLAQPYKIMGSCSNYLHLSVPDLNVNIHLRIDPKDIYYYTYLIMNKGKLLKVGRQMRELGQDVVALPLTITEDFIPSFRLVVYYTCNSNGQREVVADSVWVDVKDSCVGKLVVTLKIEGDRGARVGLVVVDKGVFVLNKKNKLTQSKIWNVVEKADIGCTAGSGKDYAGVFTDAGLAFQTNTNLQTPDRTDPECPKPATRRRRSVMLMEKRMDKVGQYPQLRKCCEHGMRENPMKFSCQRRARFIQSCVKAFLDCCNYILGLARSDLDEDIIPEEEIISRSQFPESWLWRIEELSEKDGISTKTMNIFLKDSITTWEILAVSLSNKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYQVTLLYNPAFCSQATARKPYEIPAKSSMAVPFLLVPLKVGLHDVEVKAAVFLMDGVKKPLKVVPEGIRVNKTVAVHTLDPENGQNGVQREVHAIDLSDQVPDTDSETRILLQGDAIDAERLKNLIVIPSGCGEQNMKSMTPTVIAVHYLDQTEQWEKLGPTKRKEALQLIEKGYSQQLAYRQDNSAYAAYLRKPSTWLTAYVVKVFSLASNLVICGAVKWLILHRQNPDGVFQEDAPVMSQAMTGGYQEEEKDVSLTAFVLIALEEAKDRVNSLEKNINKAGDYIENLRRPYSVAIAGYALARLGRLLEKFLTSWEEPGKDLYNVEATSYALLALLVLKDFDSVRPIASWLNEQRYYEGGYGSTQATFMVFQALAQFQKDLNLEVSIELPSRSRHTILESASLQRSKKNEDFVVTAKGKGQGTLSVVTMYHAKLKSNHCKKFDLRVDTMILDICTKYLGQDATMSILDISMMTGFSPDTGDLDLLSNGIDRYISMYELNKAFSNKNTVTIYLDKVR-------------------------------------------------------------------------------------------------------------------------LPMGI--------------------------------------------- >OWK12416.1 C3 [Cervus elaphus hippelaphus] TSGPSLLLLLLLALPMALYSMITPNILRLESEETVVLEAHGGGNIPVSVTVHDFPAKKQVLSQLNNDNGYLAVTIK--------------------------------------------------------------TPDGIPVKRDSQSSHNFGILALSNIPELVNMGVWKIKAHYEDSPQQVFSADFEVKEYVLPSFEVQLEPEEKFYYIDDDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILRRQVLLNGVQVGKSIYVSATVILQSGSDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTLTQDDGVAKLSINTQPLTIT------ATKTMQALPYNTQGNSNNYLHLSVPTLNVNFHLRTDPAKIRYYTYMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLNANGQREVVADSVWVDVKDSCMGTLVVTLKIEADQGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTSQGLETKQRADPLCPQPAVRRRRSVQLMEKRMDKVGQYSDLRKCCEDGMRDNPMKFPCQRRAQFILACVKAFLDCCKYILELARSDLDDEIIPEEDIISRSQFPESWLWTIEDFKDKNGISTKLTNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRA------VELLYNPAFCSLATAKKRHVIPARSSLAVPYVIVPLKVGLHEVEVKAAVFISDGVKKTLKVVPEGIRVNKTVAIRTLNPEHGQGGVQREVPAADLSDQVPDTESETKILLQGDAVDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQQALELIRKGYTQQLAFRQKNSAYAAFLRPASTWLTAYVVKVFALSANLDLCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFRDREKDVSLTAFVLIALHEAKDQVNV---------------------------------------NRWEEPNQKLYNVEATSYALLALLARKDYDTVHPVVRWLNEQRYYGGGYGSTKATFMVFQALAQYQKDLNLDVSIQLPSRNKHRILESASLLRSKENERFTVRAEGKGQGTLSVVTVYHAKLKGKVCKKFDLQVSSMILDICTRYLGQDATMSILDISMMTGFSPDIDDLKLIPQFLHHFPTPMLDFLPCQPSPDQPPPSSQVSHEDCLSFKVHQYFNVGLIQPGAVKVYSYYNL---------------------------------------------------------------GSVNQQRKFISHIKCREALKLKEGAHYLVWGVSSDLWGISYIIGKDTWVELWPDAEECQDEENQCEDLANFTFGCPN >XP_018109218.1 complement C3 [Xenopus laevis] --GCGLLSLSLLLVSGSYCTLITPNLLRVESEETIVIDAQGQAPFEAEVIIQDFPQKKLNLVPLNVNNGFLGATLKIPSLSKDTKQYVYVSVKSNVLEKVVLLSYHSGYIFLQTDKTIYTPGSTVLYRIYSMNIIEFLTPDGIIVKRDTILQDSSGIISQSKLPELLSLGVWTISAKYEDTPQQNYTINFEVKEYVLPSIEIILKPDTNYFYAD-ESFGVDIQAQYLYGKHVDGYAFVLFGIRKDNVKKGIPESLTRVRIDDGEGRAELKRKDLVK--YLQFGLYVTVSVVTETGSDMVEAEIEHISIVTTPYKILFTKTSKYFKPGMPFDMMVYVTNPDGSPARRIPVVVTTQGDGTTRLTMNTPVLPITVKTRRQATATMTATAYRPSKAHGNYLHISIANIPVNFNIRNTDNQIQHFTYLIMSRGRILKVGRQQRQPGQPFVTMSLPVTDTLIPSFRIVAYYIVNVGGSRDVVSDSLWVDVVDDCMGTLTVKLKLRADHKAYVGLVAVDKGVYVLNSKFKITQKKVWDSVEKSDIGCTPGSGANSEGVFSDAGLALQTSFGINTAQRSDAQCPAPAQRRKRSVALIEIKAGKASEYKKAKKCCLDGMQENLMGHTCDRRSRYILECVDAFLDCCRYYDTLGRSDEDDEYMLDSDIVSRTEFPESWFWKVEQMADVNGISSKTLNVFLKDSITTWEVLAVSLSENKGLCVGQPYEIKVMKDFFIDLKLPYSVVRNEQVEIRAILYNYRVELTHNPEFCSLSTAKKRYWIGGLSSTAVPIVIVPLTLGLHDIEVKASVFGADGVRKKLKVVPEGMRIAQDVKTVILEPEVGKGGVQEKVEALNPKNVVPRTDIDTTITLQGDAIDGNNMNHLIVVPAGCGEQNMISTTPSVIATRYLDASGQWERIGVNRREQALKNMRQGYAQQMAFRKPDNSYAAWKRPASTWLTGYVAKVFGMAQEFVLCGSVKWLILEKQKPDGLFQENAPVIHQEMVGGITTAEGDSSLTAFILIAMLECQRHVNNLQVSIDKASSYLVGLKKPYSIAITSYALALAGK--NKLLTHWEEPGKRFISLETTSYALLTLLKMKEFDLTGGIVRWLNEQRYYGAVYGSTQATIVMFQALAQYQNELNLDVSLHLPERQTYRINENALLARSRLNQDFVVKAKGKGQGTMRVVTVYHALVTEKECLNFELSVNTVSIEACARHLKVDATMSIIDISMMTGFSPDTDSLDRLMKGVDKYISKYEVNKGANDKGTLILYLDKVSHEECVKFYAHQYFEVGFIQPASVTVYDYYTPDNRCTKFYHVEEGSALLGRICQGDICRCAEENTADMRVNMACAPGVDFVYKATLTTIKKVIKQGTEDKTRNFISHIKCRKALNMQLNRDYLIWGVTGDLWRYSYIIGKDTWMEWWPNERECQQRENLCDDFETVSVGCPN >XP_040202590.1 complement C3-like [Rana temporaria] --GDRTLCLILLSLAGSSCTLITPSVLRVDSEETIVVDGHS-STFEVEYFIQDFPARNLMLANMNGGNKHLGAKVTIEGFIKDPKQYLSISVKSSNIEKVILLTFHSGYIFIQTDKPIYTPGTSVQYRLYPVNQVDILNPDGILVKNEQLYP-DTGIISKTPLTDVPSLGVWTISTRYDGTFQE-YTTNFEVKEYVLPTFEVKIKPDRSFMYAN-ETFSVAIEADYTYGKTVSGNAFVLFSLKKGDERKTVADSLSRIVIDDGKGRATVKRADLLK--ILEYRLHVSATVITEAGSDWVEAELDNIYIVTSAYKILLTRTSKYFKPGMPFHFMVLVTNPDGSPANKIPVVVVTEEDGTSKLIVNTGPLKITVKTTLQASAETTITPYQPQSGLGNYLHLTIDQIFISFHILTSSDKVQHFTYLILSKGRIISVGKQKRDQGQGIVTMSLIVTKDLIPSFRIVAYYTI----KKELVSDSLWVDVVDECMGTLEVPLTLKADHDSYVGLVAVDKAVFVLNKKYKITQSKVWDIVEKSDIGCTPGSGANNMDVFYDAGLAVESNFGMVTKQRSDPSCDAAKKRKRRSAALIEMKNQKALNYNLERQCCHDGMTSNPMGHSCDRRAKHILKCVQVFLDCCKYIKDLERSDSEGEYMKDEDITVRSAFDESWLWNIIKITDNNGVSTQQVNKYLKDSITTWEVLAVSLSKTNGICVAKPLEIQAFKSFYVDLRLPYSVVRNEQVGIRAVLYNYEVTLTYNPKFCSLSTPSKKYIVKESSTFTVPLIIVPLEVGMHDVEVKAAVFVADGVRKQLKVVPEGVRKVETILSEDLEPERGRSGEQVNVKSLKNKKIAPQSSISLIVNVKGQSIDGKNLNHLIIIPTGCAEQNMMKLAPLVIATLFLDKTNQWDKVGLHRRTEAISHMQTGYATQLTHRAKDGSYTALQSPQGTWLTAYIVKIFSLAKRMVLCGSVRWLVLSMQKPDGMFQEHFPIYYQKTRGGLGSPDPNVAITAFVTIALLESQNHVSNLQRSIDKAVQFISKLTRPHSIALTSYALARAGK--TKLMSQWNDPDSKFWSLEATAYALLTLLQIEEYDLADSVAQWLIRSHVDGEQYGTTQTIVVLFEALAKYQMVLDMDVSVNLPERKKYRLNQSNLNARSNINSDFVVKAKGKGRASLTVTAVYYEIVTEKECNHFDFTITTMSVEVCFRYRGKDLTMSIVDVTMMTGFSPDVDDLKRLQHGVDRYISQFEINKGAKDKGTLIIYLDKISHEECLKFNAHRYFEVGLVQPGSVTIYDYYSPETRCTKFYHTVEGDNLYGRICQGDVCRCSEGNSALERKDTACQAGMDYVYKATLLHITNVYKNGTQGQKRTFISHIKCREALKFKKGLDYIIFGSFNDVWQYTYIIGSRSWVEWWPNKRECQNEEYLCDDFYSLSFGCGV >NP_001098552.1 complement component C3-1 precursor [Oryzias latipes] RRALQLLLASLALSLMSLNLMSAPNLLRVGTPENIFVECQDCANQPVTISVKNHPTKAKTLATLTNDNNFQGGQITIPPFSKDPKQYVYLEAAFPGLEKVVMVSFQSGYIFIQTDKTLYTPNSKVYYRMFGVTSIEIVTPEGIILPLDPVSL--SGLHSGDQLNEIVSPGLWKIVAKFQSNPQESFSANFEVKEYVLPSFEVKLSSLRPFFYVD-ETLEIDIKARYLFGQEVNGNAYVVFGVMDQGQKKSFPDSLSRVPIENGEGKVVLKREQITK--TVGTSIFVSVSVLTESGSEMVEAELRGIQIVKSPYTITFKRTPKYFKPGMSFDVAVEVLNPDESPAGNIPVVVFTAANGMARLTINTARLSISAKTDRQAEATMQANQYS--TNSKTYIHIGVDNLKVNLNLNKQP-GNQDITYLITSRGQLVKFGRYKTR-GQVLISLIIPVTQEMLPSFRIIAFYHP---SDNEVVSDSVWVDVKDSCMGSLTLSLKVSGDPGATVGLVAVDKGVYVLNSKHRLTQKKIWDEVEKFDTGCTPGGGKNGLSVFFDAGLLFESSTASGTVYRQEKKCAAP-SRRRRASTIMDVRTTLLSQYKLQRECCLDGMKDSPVSYTCERRSEYIMACVDAFVTCCKEMLQLARSETDDSYMDSNEIVTRSNFPESWLWSDIILPPNCGSTSSVKNVPLQDSITTWEFTGISLSRTHGICVGESLEVIVRKDFFIDLRLPYSAVRGEQLEVKAILHNYRIDLAEEKDTCSAASKRGKYNVGAMSTRSVPFIIIPMKEGTLPIEVKAAVYLSDGVKKDLRVVPPGVLVKAIE-STILDPAHGKNGEQVVLNSNIPSNFIPSSPTSTQISLTGNAISGKSMGTLIYQPSGCGEQNMIHMTLPVIATIYLDKTNQWEAVGFQKRAEALQHIKTGYTNELAYLKGDGSFAVWAHGSSSWLTAYVIKVFSMANNLHICDAVKFLILRAQQPDGLFTETGKMYHGEMIGDVRGSDSDASMTAFCLIAMQESRSTVNTLPGSIDKAVAYLERLTNPYAVAMTSYALANEGKILYKFVTHWPVPGKHLFTLEATAYALLALVKTKSFEDARPVVRWFNQQQFVGGGYGSTQATIIVYQAVAEYWPEYDLKVDILLPGKSKYEFNENSYATRTDINKDIKVKATGSGEAVLKMVSLYYALPEEKECQKFDVSVQVYKLQIEVLYKDRDATMSILDIGLQTGFTPNLDDLKALSGGRFPLISKYEMNTALSERGSLIIYLDKISHPEEISFRVQQTMEVGVLQPAAVSVYEYYE-QTPCVKFYHPEREGGQLLKLCKDDECTCAEENSNDERTSKICESKIEYAYKVLVERVQDSIKEGSRGKLRPFLSYPHCRDALNLQKGKTYLIMGSSRDIHKYQYVLGERTWIEYWPTAEECQGDEHTCLGLDEMLFACQQ >XP_030274930.1 complement C3-like [Sparus aurata] RRTCVTNLWLLAFAFFSLQVMSAPNLLRVGTTENIFVECQDYGNIPVEIIVMNHPTKVKRLATLTNENSFQQAQIMIPTFSKDPKQYVYLQARFPDLEKVVMVSFQSGYIFIQTDKTLYTPESTVLYRMFAVTAIEIVTPEGIILPLDPVSL--SGIHSGDKLGEIVSPGLWKVVAKFHNNPQQSYSAEFEVKEYVLPSFEVKLTPVSPFFYVD-PDFTVNIRATYLFGEEVDGMAYVVFGVMQEGQKKSFPGSLQRVQIAKGIGVVTLKREHITQ--TVGSSIYVAVSVLTESGSEMVEAELRGIQIVTSPYTIHFKKTPKYFKPGMSFDIAVEVMNPDETPAQGVAVVVFTAANGMAKLTINTESLRITAKTKRQASATMTALPYT--TKSNNYIHIGVDNLKINLNLNRQS-QAKDITYLILSRGQLVKKGRYHTR-GQVMISLIVPVTKEMLPSFRIIAFYHT---DGNEVVSDSVWVDVKDSCMGSLKLRLKVTGDPEATVGLVAVDKGVYVLNNKHRLTQKKVWDIVEKYDTGCTPGGGKDGMSVFFDAGLLFESNTASGTPYRQELKCQARSSRRKRSNTIMNVTTSLVSKFELERECCSDGMMKTPLSYSCETRSEYIGACVKAFLHCCKEMLQLARSEEDDSYMDSSEITSRTQFPESWLWSDIKLPPNCDTTTFEKNVPLQDSITTWQFTGISLSRTHGICVGEPLEVIVRKEFFIDLRLPYSAVRGEQIEVKAILHNYSVDLIEEVDVCSSASKRGKYKVGPQTTRSVPFIIIPMKQGQYRIEVKAAVSLNDGIMRMLRVVPQGVLIKSPK-IVTLDPANGVGGIQKVINSEIPKDLAPNTPTSTQISVTGNAVGGQSMGTLIQQPAGCGEQNMIRMTLPVIAATYLDKTNQWEAVGFQKRAEALQHIKTGYTNQLAYRKDDGSFAVWAHKSSSWLTAYVTKVFAMANNLVICDAVKFLILNAQQPDGMFREVGKVYHGEMIGDVRGADSDASMTAFCLIAMQESRTTVNSLPGGIDKAVAYLEALTNPYAVAMTSYALAQENKILYNFISHWPVPKGRVYTLEATAYGLLALVKAKAFEDARPVVRWFNKQQKVGGGYGSTQATIMVYQAVAEYWPEYNLDVDILLPGRSKFNFNNNHYATRTDINENVTVTATGSGEATVTMVSLYYALPSEKECQKFNMSVQSYKLRIEVLYKDRDATMTILDIGLLTGFTVDRNDLDLLSKGRARIISKYEMNTLLSEKGSLIIYLDKVSHPEEITFRIHQTFKVGVLQPAAVSVYEYYE-QTPCVKFYHPERRAGHLLRLCRGDECTCAEENSNEQRTAMACESKIDFVYKVRLERVLEVIKEGSQNQVRAFLSYQHCRESLDLTEGKTYLIMGTSKDIHRFQYVLGERTWIEYWPTEAECQTDIHTCLGMEELVFGCEH >XP_015824898.1 PREDICTED: complement C3 [Nothobranchius furzeri] RRTNLLLLASLAFSLMSLKLMAAPNLLRVGTAENIFVECQDCGDISVDIKVMNHPTKTKELATLSNNNNFQQGEITIPPFSRDPKQYVYLQAKFPDLEKVVLVSFQSGYIFIQTDKTLYTPNSKVYYRMFGLTDIQIQTPDGIILPLDPVSL--DGIHSGDQLSEIVSPGLWKVMARFQSNPQQSFSAEFEVKEYVLPSFEVKLLPDTPFFYVD-DDFRVSIKATYLFGREVYGTAYVVFGVLEDGVKRGLPSSLSRVPITNGEGQVTLKRSHLTD--TVGKSLYVAVSVLTEGGSEMVEAQLRGIEIVTSPYKITFLKTPKYFKPGMSFDVVVEVVNPDGSPANNVVVEVLTAPNGVARLTINTQSLEIIARTKRQASANMVATPYS--SNTQRYIHIGVDNLKINLNLNNQP-HQTDITYLITSRGRLVKSSRYKTK-GQSLISLILPVTKELLPSFRIIAFYHP---ADNEVVSDSLWVDVKDSCMGSLTLNLKITGDPGATVGLVAVDKGVYVLNNKHRLTQKKVWDIVEKYDTGCTPGGGSNSMNVFFDAGLLFESSISLGTPYRQELKCKTT-ARRKRATTILSVRTNLMSKYNRQRECCLDGMKEIPLSYTCKRRAEYILDCAEAFVHCCNEMLRLARSESDDSYMDSQEIVSRTNFPESWLWSDIKLPPNCESTSFVKNVPLVDSITTWQFTGISLSRTLGICIGDPLEVIVRKEFFIDLRLPYSAVHGEQLEIKAVLHNYS--------------HKHGLDLNSL------------------------------------VVPQGVLVQTSQ-DVTLNPTEGQNGQQVKLNSNIPNDLVPNAPTRTDISVTGNVLSGSSLGTLIKAPGGCGEQTMISMTLPVIATLYLDKTNQWETVGFQRRNEAIQHIKNGYRHELIYRKTDGSFAVWADKSSSWLTAYVAKVFAMANTLHICGAVKYLIINAQQPDGMFREIGRVYHGEMIGDVRGKDSDASMTAFCLIAMQEARTHVTSLQSQIDKAISYLETLTNPYAVAMTSYALANENKILFKFANHWPVPGNKIFALEATAYALLALVKSEAFEDARPVVRWFNQQQFVGGGYGSTQATIMVYQALAEYWPEYNLNVDILLPGRTKFNFNENQFTTRTDINQDVNVIATGSGEATVKIVSLYYALPKEKECQQFNMSVDTYRLRIEFLYLNRDATMSILDIGLLTGFTVDNDDLNLLSKGPARVIDRYEMDSVLSERGSLIIYLNKVSHPEEITFRITQPAKVGILQPAAVSIYEYYD-RTHCVKFYHPQRRAGQLLRLCKENECTCAEENSNDERLAKICESKIEYAYKVSVERVIEVIKEGTLGKLRTFLGYQHCREALQLKQGRTYLVMGSSKDIHRFQYVLGERTWIEYWPTSEECQSHEHSCLGLEEMVFPCQQ >XP_038046850.1 complement C3-like isoform X2 [Patiria miniata] ------------------YFIVAPNLVRVDVQETILVSVLGTNQIPVTLYFQ-LTGSNDRISFVRQDESQEALRIRRDQQLQTSQQFVTLVASANTDRRVILLSYQAGFVFIQTDKPLYTPKQRVDIRVVALDQVDIISPDDIIVERYKQRP--DGFLTLSVFPSNPVFGNWSVSAYYGHQFKASSTVQFEAKEYVLPKFYVEVAPQSLYIVPE-QNLISKVTARYIFGEPVVGNFYVKYGVLEDDGSLMLQSKEGRLN-EVGEAFQDLDMNDVKV---MGKRLVIQAFVTDTATGETINTNNTQVTFSRTPYKFNWDLTQRYFKKGLSFSVKANVQFMSGLPAEDVPVIAISGPQGEVDFRLDVPEITITLRTNTEGTITVLAQA----SSNNEYLVVRVPQSTVEVQLTHPD--VGVLNYFVIAGGRIVHKGAKNQV--NLNTALGFEVTHEMAPSSRVVAYYTD---ANGNVVADALLIDVEEKCKNPIGLQLEILAKEDTNVGLVAVDEAVFKLRNYHRLTQKKVFKRMAGYDLGCGPGGGQTSATIFKNAGVTVMTNAQLDVPHREALGCPEPVRRARRSAN-DTEREQILSNYEVNREYCEKGMREGSVQLTCAQRAKLMAPEIRAFFDCCSVLSDRGRVDAGAGGVNLEDILVRSNFPESWLFDNVITQSDDDDGRVLYPTTLPDSVTTWVIEAVGMREVHEMCVAEPIKLEVRPPFFLDIGMPYSVQRFEQIEIVASVFNYGVYLRGKEGLCSIAQPGEYSQVEAKKPASVKFVIVPLEVKNIPIEIVAMDQHRDAIEKDLTVRPEGYEKKISV-PVTLDPANQGEEKQIFIRYSVNRNAIPGSH-KARMSLVGTVLGG--LDKLLRIPGGCGEQTMLGLAPNVYVYTYLKHTDQFTA---ALETSSERYVFNGVKHELTFRKNDGSYAAFTRPSSTWLTAFVAKIFCKAKDFNICKAMEWLITQRQQDDGSFTERNAVIHKEMSGGVQG---KASMTAFVLISLLECECDAINKDDSVAAATALLEDLTRPYAIAITAYALALANSEAIQMLPYWYSARPKAIEVETTSYALLALLQMEEIQYTHAIVNWLTNQENYNGGFVSTQDTVMALQALSEYAYDIDINCEVKCDESEDFSLNANALVREQSQEMNVFISTEGAGMGQFKFEATYYIPEPDVTCD-FDLLINYLSYDIQVRYLREKTGMAILDVGLYTGYKAVQEDLQTVMDNSGGRVERYE-----ETDHSVVFYFEDIPGAIRIQFRAEREFNVGKVQPVAVHVYDYYNPTEECVKFISPKEGSNLLGKLCVEDTCVCAAGKKVYDMTQMACASKAHFAYEVTVTTIDAPLKQGLKDATRVFAKSKSC-DTPDLQMTK-YLVIGSGGLPTKYKYVIDDRTFFYEYPTILQVNKSKKIHAKLTELKEGCAL >XP_030852887.1 complement C3 [Strongylocentrotus purpuratus] TMGSFVLIFVIAIASLVPFFVTSPNVFRVDVPESVVVTLIRSNVQNVQVRVSLRPGSGVHFSAVSPGSSQLFVEIQADNLMRNEFQHMVLKAESLDKETEILVTLQSGYVFVQTDKPIYTPNQDVIIKVMSLDHVEIIDPSGTSVKRLRQTQALSGFLSGERFHSHPALGIWTVSAFYGPEFLVESSATFVVKEYVLPTFSVSIETPK-YILAG-YSVVSTINAQYVFGKPVLGRYTFKYGVIQDGT---VQELGERQGLIGDTGRAVVTLDDLSTDFDRGRHFHAKAIVHESATQFSEASINTKAIFVDSPYKFSRKRTVQYFKAGLNLQVNLDLTFANGDVATDVPVSVNTDDQGGVSMDFGVQSIHIVASTHNQADMSFGVSLADS-ANGNDYLVIRPRDVTTDFLVQRIGNEDIDLHFLCITGGKIVLQGVQQRI-SAFGTNLPITIRSNMVPRMRLIVYYVT---MDGSVIADSLLLGVEEQCRQNQEVRVEVTAPNNSYVGLLAVDKAVYLLRNKDRMGKRKMYDWMRSYDTGCGPGGGQNTAQIFKDSGMTVLTNAGLDVAIREEIECVDEPTRKKRSI--------------RDQQCLYDPTYL---------------------VNCLADK----RSGGGVGYQN-GDVRVREDFKETWFFDVVSMP---DGSPYLYPISTSSSITDWHLTAVSFSPTQGMCISET-TVSVFQDFFIQLHLPYSVVRLEQTQVIATIFNYGVNFTVEDGLCTAENPTIRHFVESRRAASAAFIVRPVEVGEFQITVTAGG-KRDIVRKTLLVVPQGVMKRKGR-SVILNPGRFGENQQFQMTISLPEDSIPDTE-SCSVKLIGDPIGG--LDHLVRRPRGDGEQTMIFLAPTLFVYQYLIAVGSDTV---EQEARIYDYIADGVVRELTYRQPNGAYAAWTRPGSTWLTAFVVKVFSQANRFHVEGSINWLIDNNQLPSGAFQESRQVFYQEMIGAVQG---ETSMTAFVLISLLESRNANQKIDDAIGNATEYLVDIDRVYDKAIVTYALALAESIANDYLPYWLQRRPSAVEIETSGYALLAQIALHDYQKAGKVALWLSNQQNYGGGFVSTQDTVVALQALAKYTNTINMDCELATEQIT-HRYHGDDYVQEESIGRSLTIGCRGTGIAKAYVELRYNTEQSDIDCP-FHLNTSGLRITVCTSYNGGTTHMSILDVGLYSGFNPEIEGLEEMVNGSE-IISSYE-----ASSRSVIFYLNQIPDDLCFTFSAKSYVVVGNVQAAAVHLYDYYDPDKSCTISYKPGPGSALLSTLCSESECICTGGSSIFELERAACASHSSYALKIRIDTVLNPIKTGDHQAQRQLFINEDC-DCPKRNIGGTFLLVGQKSLKYTFRYVYGPTSKLEVWLQTRRPRN---VFDKLEQFETACSN >XP_031565662.1 complement C3-like [Actinia tenebrosa] FTDSKMLLTLLTILLMVGYVITAPNIFYVGVPQPIHVALFDVHTIELELRVFLSYGETKVIARISADNGKLFLTVGPEV-FQSSRGFVYLLSRIKGKNTKVNVSYSDGVILIQTDKPIYTPKQTVKIRVVPLGNLVVKNPHGIGVRQESLNT--LGFISKNDIGSYALAGIWTIEAYYGHQFLYNASSRFEVREYVLPRFSVKISNPL-YILPT-DSFKVKGTAKYTYGKPVQGTATVRLSIAGNPQEKAMSLSTSKIKLVNGEFEHPIKMDRIKTKLREGYRLHIEADVTEKSTGKTERAVERSVYFVTTPYLIEYVNTARYFKPGLPFSIVVIVKFTNGQVARKIPMKVNTDDNGRAEFVINIAELQIKVKTNQNAFKELVMDA----SESHELMKLRQTNAVCDAVLTSKT---DQLTYFVISRGQIIYSATIKKL-LGIITTISFKVTSPMSPSSRLFAYYVS--KETGRVVSDSILLEVEHKFPNPIFLNIKIVGTVGTKVGLLGVDQSVYLLSKSNILTADSVFKKQEELDLGCGAGSGRNSEDMFRNAGMVVLSS---DIEVSGEQKCKGEHKRERRSIE-------------HRDFCCSLGNKTDTIKRSCFRRLKDLDDCRKTFWMCCIHKFARARSGVDLEALDFGDIQTRQYFPETWINKELTISLQHKCGSAVLPVSLPDTMTTWVVQAIGVSSSAGFGIAKPLHITTFKPFFIYLSMPYSVQRGEEITILATLFNYKLFLKGDQGFCSAAQPGKMTNIPPQDTVAFPITIVPIKFGKVPIEVIAVGIGDDRVLKTLNVVPEGIEERLTQ-SYVLDPQEHKDFKQKKIKLDIPKNAIPGSI-SAKAYFTGNLAAG-QMVSLLQMPDGCGEQNMVRIAPNVYILHYLKKTNQMTP---ELEKKKEKFIQEGYIHELNYRKKDGSFALFKNKGSTWLTAFVLKVFCQASKLVLCQSAKWLI-GNQRQDGAFVEHANM--RSIQGGVYT--SDVTLTAAVVIALKQCQCGMAEVNSAVERAVGFIETLADAYSLAITTYALVLANSRANQKLNRYWETGSKARNIETAGYALMAQVALNRFEYAGPIVVWLTKQRSFGGGFVSTADTCVALESIAKYSFQLDLRIRMK-----IMRITNNAFMQQEQTGDEVGIQTSGSGVGQMQVDIKYNVPYKENECD-FDVKVIKLVLRVCTKYRKGQTGMAIIEVGLVTGFSADEDTLIKLVEKKNNSIERYEL-----SDRAVVFYVNQIVNRICIAFHLIRIFDVGIIQPVPIKVYXYYEPDTKCTLFYNLGSKRRPVGS-CKKEKCKCTQGMNIDDLINEVCN-VYNYAFKGKVVNITQIIKQGSTQKAYLFNKPGIC-HYPDFEFEDEVFIMGKNK----GVQFLDRDTFVKTL-----------RQRFVNKIAGKCT- >XP_039271128.1 complement C3-like [Styela clava] --KLLQLCMQLFIVLCTRHLLIAPQILREGVRETAVLNLYNIGRIDVVATVKLEGVTNFEIK--NEDATKPIMKIKYDKVLPSKRQYVELLVSAKQGQLRMRLIESSGYIHIQTDRPIYRPEERVNVRVIALTEIVIRIPDNVGVEKKLLRMP-AKFIDTSELPEYPVYGIWSIQARYTDEKVVRSTTTFDVRPYVLPTFNVRVLLDDPYVLVKTEYIRGTITAEYSYGRKVSGPYFLAAKLNRPDIKSKMPELRRMAKLRGGKQRFEIKATEVLTVIGEGATIEIDVAVTGEAEGVVESDRSRPIMFVRSPYQLDISRMSKYYTPRTSFEIKIDVLDSTNSPVKKVELILESDENGQVNFKIGMDKRTYTIQTRNLAKLDFTLHPYI--SSSGSYLQLSAVNFGIDVWYKSAP----RISYVIMARGAIISTGVHIPKKGSVNTNIKIEVKGEMVPSFRFFVYFFS----GKELLSNSLWIDVKDACKQELQVNVEYIGSPNAILGMSAVDRAAYFLYDKGRLTRSSVFEALNLYDEGCVREGGKNAQHVFEEAGLQVVGGPYSAKDDFTNH-CEAKTKRKKRSSP-KNIVAKLEKE--LERKCLMDGSWENLYGTSCVERAEAVRECAEKFLKGCEDYANVAGFQAVA-------NNVRSNFEENMLWADVILG----DGKYTRGVVAKDSITTFEFDTVSMHEIDGFCVAPTQNVTIFKDTFVQLKLPYSLKRMEQAEIRATVFNYAVHVKMGEDICSHFRQGKFDEVDANEAEATSLVLMPLRVKQVDIEVKITNVDIDHVKRSILVLPEGEIKNDIKGTYAIDLKNRPSYIDRKIELRFPKRYIPGSR-QCWIYPFSTKQPKNDIKNLIRLPGGCGEQTMLSMGPNVMAHKYLKLVGKMKD-GSAEETGSIDKMQKGFANELKYRTSTAPWSVFPRAPSVWLNAYVNKIFAQAKQFPICTSINWLV-DQQNPDGSFDTGGRVIHQEMHGAVGS---TLSLSAYVMMSLVESQSYTKKVEISILKATDYLEQMEQPYALSLVCFALSVSNPRMRKKLAYWYKRNAKAIDVEATGYALLSILYAQSLDVTRKIVLWIIQQRDEKGGFSTTQDTVVGLQALAEYMRDVKIDLTISSATGSRLHLDSNENSTTPISGGELNIQARGEGEGTLSYRCVYRTLVDEDACH-FDISVSILKLKLYISKPKEPSGQSIVEINLISGYEVMEDTLVKLSETVDASIERYEI-----AKQKVFLYLSDITEK-KLAFRISRSVYVGRPEPSTVTVYDYYEPSVRCSKFYNVPEQNLKLRTLGSEDICKCAEGGNCFDLAGTACK--SDYVYEVKVTQIVEVYKAGDRNQNRNFSVRRDCFESCRLKKDRTLLMIGNGVEMNYPHYRLGAGIFVERIYPTTKCKKSKKKCRKLKKKTLGCDR >CAE1304902.1 unnamed protein product [Sepia pharaonis] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EIQLKGSPRATVGLSAVDKAVYLINDKNKLTRKLVKDTMKLGDLACSPGGGLHVGQVFYHAGFVIMTQDLDRTPATENILCSLKQITAEVSFG----------RYRASDFCCISGRYR--RGHNCKQEFSYYRFCRSAFMQCCNPATPSARLRQDAKSIS---PIFSLYFPESELFQEYRLN----SGLHKLNFTLPDSLTTWHIQGMSLSDTSPFCVSKPISLTTFKNVITKLNFPRVVKRLEQIYIKAVVYNYKVNFHETKEICSHAAPGKPFSIPAKDIGVAGVVIVPLKAGNFTIHIEVYENTLEIIEKVLHVKYEGVKKTNSF-SLMLDPSGASQKMQRIMKLTQPAEAIDGSA-KGDIVITGTTLKE--PHKLLDKPYGCGEQTMIFLAPCVYILSYLNSTNQGSQ---VIYENATRYIRLGILREQEFRKMDGSYAAFDNPSSVWLTAFVLKVFCQASEFLTKSAMTWLF-QKQRLDGSFIEDYPVIHQEMVGGVN----DRVMTAFVLISLMECGYEIYRRKNEIDLAIRYLEVTYDTYDMAIISYALALADSEARIKLSAWYHTEESYLSVEATAYALLTEMHYGEVEHVGPIVKWLIEQRNSAGMFKSTQDTVMALQALAEYGPDINLFFNLTSSRAHHLTVNETSLWSHIPMNDEVLIESMGIGSAQMELNMWYYRPPTQRECH-FNVTHITICMKIYLRYLGSDPGMVVLDMDLLTGYDTHEELLEQLK--LDRLIAKYHK----HGNSRLTLYFNTIPFEIEIKLLMFRMIYMNRLMPAPINVYVYYNATESCTKFYQLSREKDLINLLCDSSVCKCAQRDKLKFLEKKSCA-KEQIVMIVNMTVQEDLSKTDIEEHVAIFQK-GIC-HCPHVKVGEIYLIMANKRVRTLHKFWVDSSGLM--------INKKNQEIDIFEQKAAFCG- >XP_006565503.2 alpha-2-macroglobulin-like protein 1 isoform X1 [Apis mellifera] -NKLVFLVLFICSTFLHCYVFTAPKKLYAGEIETGCLSLHNLAHVHLEL-VFSFLEGQEVLAVVKTGTETCLLAVPSPI-----TAILRLKIKFDKSETDVEIEHDSLLTFVETDKPTYKPGQDVKIRILMLMEVWIENPSFVKVKQTNVST--NGMAQLTPLSPEPSLGSWHIKVMKKKPYPNLHSTTFKVEKYVLPKFQMTINSPQ-YILAN-ENVTWNICVKYSYGKPVKGNLLLKLTPQTPSWTRLLPAIRYETKLDKGDGCTDFVLSGSVLGLAMDPNNIVLIAEFTEAGTGIVETTISRTVVLHEALKLEYEHTPKYFKFGLPYHGKLRVLRYDDTPAPNEKIQIRSSTDGFVDFVVPPQLLSFVATAVNQPSTSITVNPWY--SPSDSYLTVARGKYSFNVMYTTSSNETISFHYSINSKGSILIYGHVKHKPNRDTIPLSVKVTPSMAPVSELLLYYVR---SDGEIVATTYTIEVGHCFENKV--QYHVEAAPRSLCAISAVDKSTLFLSKSNLMSSTQTFDALKRFH--------PTPKFYFPWENSRCKSAIGPEEMKEEINHLPQFLRSKRQTIT-----YSKRVNYVAVQAFVDFGVIV---------MSDLVLPCPWLFMEYTALSVAAAAMDSGIGYVDQNQATLRSYFPETWLWELVPIG----EGKITIERTLPHTITDWVGYTTCISPTHGLGIAPPTTITAFQSFFLDYNLPYSIKRGEIMRFKVSLFNYMIKLEEMEKIDLHLSEPTASCVKPRDNIVHEYILKPRVIGEVNITVTAFVFTQDVIVKPILILPEGFPVEETK-SALICPKD--SDDSSMWELTLPKDAVPDSG-RAYLNLIG------NLDKLIKLPKGCGEQNMILFVPNNHVIKYLDAMRINKP---DLRAKAIRNMEKGYQRELKYRFMDGSYSAFEGESSIWLTAFVLKSFAQAASLVLESSVSWIT-MNQLEDGCFPVIGTVFHKSMKGGLQEHGSSSALTAYILISLLESGV--PLSPSVVNDAQKCLEN-DDLYTTVLTTYVLALLEHSSMKSLIWWEDKSKPSISIEMTAYVILTLLKLGELSEALKAVRWISKQRNSEGGFTSTQDTILGLEALTKYANITDLSV-LVTASKEVYKLQENRVILKQILPTIVEIFAQGEGCVLIQSNLKYNVASS---SDAFDLSAELQEITICSRYKMEESNMALLEVGIISGYVPDRASLHSLLDPSS-KVKLFE-----EDQDIVTIYFNKLTGT-CISFRIIQEYFIDHLKPANIKLYDYYQQELTVSTNYKIPS-------ICSSAQLTTPNEMNTYDYKTEAATLTSTFVTEDQTVRIVKILKINEPSPTRINQSCPICMDVLPFRKVRLLLDLHISREVKRFALIINKDNDFLTSGNQKQTLNDSFVPCKLAEIRIQCTY >NP_033908.2 complement C3 preproprotein [Mus musculus] ASGSQLLLLLLLASPLALYSIITPNVLRLESEETIVLEAHDAGDIPVTVTVQDF-LKRQVLTVLTGASGHLRVSIKIPAEFNSDHKYVTVVANFGEVEKAVMVSFQSGYLFIQTDKTIYTPGSTVLYRIFTVDVILIETPDGIPVKRDILSSNNHGILPLSNIPELVNMGQWKIRAFYEHAPKQIFSAEFEVKEYVLPSFEVRVEPTETFYYIDDNGLEVSIIAKFLYGKNVDGTAFVIFGVQDGDKKISLAHSLTRVVIEDGVGDAVLTRKVLMEGVRVGKSLYVSVTVILHSGSDMVEAERSGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVFVTNPDGSPASKVLVVTLTQDDGVAKLSINTPPLTITVRTKRQATKTMEAHPYSTMHNSNNYLHLSVSNLNVNFHLRTDPAKIRYYTYLVMNKGKLLKAGRQVREPGQDLVVLSLPITPEFIPSFRLVAYYTLGASGQREVVADSVWVDVKDSCIGTLVVTLRIEGNQGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKNYAGVFMDAGLAFKTSQGLQTEQRADLECTKPAARRRRSVQLMERRMDKAGQYTGLRKCCEDGMRDIPMRYSCQRRARLITNCIKAFIDCCNHILGLARSELEEDIIPEEDIISRSHFPQSWLWTIEELKEKNGISTKVMNIFLKDSITTWEILAVSLSDKKGICVADPYEIRVMQDFFIDLRLPYSVVRNEQVEIRAVLFNYRVELLHNPAFCSMATAKNRYKIPPKSSVAVPYVIVPLKIGQQEVEVKAAVFISDGVKKTLKVVPEGMRINKTVAIHTLDPEKGQGGVQKDVPAADLSDQVPDTDSETRIILQGDAVDGERLKHLIVTPAGCGEQNMIGMTPTVIAVHYLDQTEQWEKFGIEKRQEALELIKKGYTQQLAFKQPSSAYAAFNRPPSTWLTAYVVKVFSLAANLVLCGAVKWLILEKQKPDGVFQEDGPVIHQEMIGGFRNKEADVSLTAFVLIALQEARDQVNSLPGSINKAGEYIENLQRPYTVAIAGYALALMNKYLGKFLNRWEEPDQQLYNVEATSYALLALLLLKDFDSVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDLNMDVSFHLPSRSTFRLLENGNLLRSKQNEAFSLTAKGKGRGTLSVVAVYHAKLKSKVCKKFDLRVSTMFLEICTKYLGVDATMSILDISMMTGFAPDTKDLELLASGVDRYISKYEMNKAFSNKNTLIIYLEKISHEDCLTFKVHQYFNVGLIQPGSVKVYSYYNLEESCTRFYHPEKDDGMLSKLCHSEMCRCAEENNLNVRLDKACEPGVDYVYKTELTTIQQVIKSGSAGQQRKFISHIKCRNALKLQKGKKYLMWGLSSDLWGTSYIIGKDTWVEHWPEAEECQDQKYQCEELGAFTYGCPN >NP_058690.2 complement C3 precursor [Rattus norvegicus] TSGSQLLLLLLLASLLALYSIITPNVLRLESEETFILEAHDAGDVPVTVTVQDF-LKKQVLTVLTGATGHLNVSIKIPAEFNADHKYVTVVANFGAVEKAVLVSFQSGYLFIQTDKTIYTPGSTVFYRIFTVDVIVIETPDGVPIKRDILSSHNYGILPLSNIPELVNMGQWKIRAFYEHAPKQTFSAEFEVKEYVLPSFEVLVEPTEKFYYIDDKGLEVSITARFLYGKNVDGTAFVIFGVQDEDKKISLAQSLTRVLIEDGSGEAVLSRKVLMDGVRVGKSLYVSVTVILHSGSDMVEAERSGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVFVTNPDGSPARRVPVVTLTQDDGVAKLSVNTPPLTITVRTKRQATRTMQAQPYSTMHNSNNYLHLSVSNLNVNFHLRTDAAKIRYYTYLVMNKGKLLKAGRQVREPGQDLVVLSLPITPEFIPSFRLVAYYTLGANGQREVVADSVWVDVKDSCVGTLVVTLRIEGNQGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKNYAGVFMDAGLTFKTNQGLQTDQREDPECAKPAARRRRSVQLMERRMDKAGQYTGLRKCCEDGMRDIPMKYSCQRRARLITSCLKAFMDCCNYILGLARSDVDEDIIPEEDIISRSHFPESWLWTIEELKEKNGISTKVMNIFLKDSITTWEILAVSLSDKKGICVADPYEITVMQDFFIDLRLPYSVVRNEQVEIRAVLFNYRVELLHNPAFCSMATAKKRYEIPPKSSVAVPYVIVPLKIGLQEVEVKAAVFISDGVKKILKVVPEGMRVNKTVAVRTLDPEHGQGGVQRDVPAADLSDQVPDTDSETRILLQGDAVDGERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDQTEQWEKFGLEKRQEALELIKKGYTQQLAFKQPSSAYAAFNRPPSTWLTAYVVKVFSLAANLVLCGAVKWLILEKQKPDGVFQEDGPVIHQEMIGGFRNKEADVSLTAFVLIALQEARDQVNSLPGSINKAGEYLENLQRPYTVAIAGYALALMNKYLTKFLNRWEEPGQQLYNVEATSYALLALLLLKDFDSVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDLNMDVSLHLPSRSVFRLLESGSLLRSKQNEGFSLTAKGKGQGTLSVVTVYHAKVKGKACKKFDLRVTSMILDICTRYLGVDATMSILDISMMTGFIPDTNDLELLSSGVDRYISKYEMDKAFSNKNTLIIYLEKISHEDCLSFKVHQFFNVGLIQPGSVKVYSYYNLEESCTRFYHPEKDDGMLSKLCHNEMCRCAEENSLNERLDKACEPGVDYVYKTKLTTIEQVIKSGSAGQERRFISHVKCRNALKLQKGKQYLMWGLSSDLWGTSYIIGKDTWVEHWPEAEECQDQKNQCEDLGAFTFGCPN >NP_001035559.2 complement C3 preproprotein [Bos taurus] TSGPS-LLLLLLALPMALYSMITPNILRLESEETVVLEAHGGGTIQVSVTVHDFPAKKQVLSQLNSNNGYLSVTIKIPAELKSDHKFVTVVATFGNVEKVVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDFITIETPDGIPVKRDSKSSQNFGILTLSNIPELVNMGVWKIKAYYEDSPQQVFSAEFEVKEYVLPSFEVQLEPEEKFYYIDDDGLKVNIIARFLYGEQVDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILKRQVLLNGVQVGKSIYVSATVILQSGSDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTLTQDDGVAKLSINTQPLTITVRTKRQATRTMQALPYNTQGNSNNYLHLSVPTLNVNFHLRTDPAKIRYYTYMIMNKGKLLKVGRQYREPGQDLVVLPLTITSDFIPSFRLVAYNTLNAKGQREVVADSVWVDVKDSCMGTLVVTLKIEADQGARVGLVAVDKGVFVLNKKNKLTQRKIWDVVEKADIGCTPGSGRNYAGVFTDAGLTLKTSQGLETQQRADPQCPQPATRRRRSVQLMEKRMDKAGQYSDLRKCCEDGMRDNPMKFPCQRRAQFILACVKAFLDCCEYILELARIDLDDDIIPEEDIISRSQFPESWLWTIEDLKDKNGISTKLMNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAILYNYRVELLYNPAFCSLATAKKRHTIPARSSVAVPYVIVPLKIGLHEVEVKAAVFISDGVKKTLKVVPEGVRVNKTVAVRTLNPEHGQGGVQREVPAADLSDQVPDTESETKILLQGDAIDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTDQWEKFGLEKRQESLELIRKGYTQQLAFRQKSSAYAAFQRPPSTWLTAYVVKVFALAANLDLCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFRDREKDVSLTAFVLIALHEAKDQVNSLGRSIAKAGDFLEELRRPYTVAIAAYALALLGKRLTKFLNRWEEPNQKLYNVEATSYALLALLARKDYDTTPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKELNLDVSIQLPSRNRHRILESASLLRSKENERFTVKAEGKGQGTLSVVTVYHAKLKGKVCKKFDLRVSSMILDICTKYLGQDATMSILDISMMTGFSPDVEDLKTLSTGVDRYISKYEMNRD-SNKNTLIIYLDKVSHEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCRCAEENTLEDRLDKACEPGVDYVYKTRLIVIENIIKSGSVKQERKFISHIKCREALKLKEGAHYLVWGVSSDLWGISYIIGKDTWVELWPEAEECQDEENQCEDLANFTFGCPN >NP_990736.3 complement C3 [Gallus gallus] ---CCCPSCSAFCSMRSPVTMVTPAVLRLDTDEKVVLEAPGLAPTEANILVQDFPQKRKVLFQLNPAEGMMAATVKVPVLLPPVKHFVSVVARVGQLEKVLLVSLQSGHIFLQTDKPIYTPGSTVLCRLFALSIVEVKTPDNVIIKQVPVSSPMNGIFSINNLPEVVSLGTWTITAKFEDSQDQVFSTQFEVKEYVLPSFEVTLDPQEKFLYIDREDFRVTITARYLYGKNLQGTAFVLFGVVVDDEKKTIPQSLQRVKVTDGDGEAVLPMAMLRQ--RVGHSLYVTVTVLTESGSDMVEAQRSGIRIVTSPYTIHFTHTPKYFKPGMPFDLTVYVTNPDNSPAPRIPVKASTQRDGTAKLVLNMPSVPITVRTDRQASRQIVAEAYQSQGNSGNYLHLAVGNLPINFHLKSNRKSVSYFTYLILSKGHIVHVGRQPREGDQSLVTMSLPVTANLIPSFRIVAYYHV---KPGEIIADSVWVDVKDTCMGSLVVRLHIEGDHKAHVGLVAVDKAVYVLN-KNKLTQSKVWDTVENSDIGCTPGSGRNHVGVFADAGLSLTSNVNINTEQRSEVQCAKPAKRKRRSVRLIKHKGTKMAEYSNLRKCCEDGMKENLMGYSCEKRATYVLACTEAFLSCCLYIYELARSEVDDAFLSDEDITSRSLFPESWLWQVEELTNEQGISMKTLPIYLKDSITTWEVLAVSISENKGLCVADPYEITVMKEFFIDLRLPYSAVRNEQVEVRAILYNYWVELMYNPALCSASTTKTRYQLEPQSSHAVPFVIVPLQLGQHDVEVKAAVFVSDGVKKKLRVVPEGMRLEKTVKIVELDPKTGNNGVQEKVKAANLSDIVPNTESETKVSIQGKATDGTKLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDSTMQWETFGINRRTEAIELIKKGYTQQLAYRKEDGSFAAFTRPSSTWLTAYVAKVFAMAINMVVCGAIKWLILEKQQPDGLFQEDAPVIHKEMVGGYHGAEPSVSLTAFVLSALQESQKYVKSLDGSIAKASDYLSSLTRPYTVALTSYALALTGKKV--LMTHWAERNAHTYNIEGTSYALLALLQMEKAELTGPVVRWLAQQNYFGGGYGSTQATILVFQALAQYHLELNLDVSVLLPRRATYRIENNALVARSKLNEDFTVKAEGTGKGTMTVVTVYNAKVPEKECDNFDLRVSSVKITICTRFLDVDATMSILDISMLTGFSPDVQDLKSLSEGVERYISKFEIDHALSNRSNLIIYLDKVSHEECIAFRAHQHFQVGLIQPASVTVYSYYKIDDRCTRFYHPDKAGGQLRKICHGEVCRCAEENTVNERIDLACKPGVDYVYKVKVVSILTVIKMGTGGSNRTFVSHKQCRDALSLQKGQDYLVWGLASDLWVFSYLISKDTWLEAWPLEESCQDADLLCQDFTEFSFGCPT >XP_020936478.1 complement C3 isoform X1 [Sus scrofa] TSGPR-LLLLLLTLPLALYTIITPNVLRLESEEMVVLEAHEGGDIRVSVTVHDFPAKRQVLSTLNNANNYLSVNIKIPAEFKSEHKFVTVQALFGNVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVDVVTIETPEGIDIKRDSLSSHNFGILALSNIPELVNMGQWKIRAHYEDAPQQVFSAEFEVKEYVLPSFEVQVEPSEKFYYIDDNGLTVNIIARFLYGESVDGTAFVIFGVQDGDQRISLSQSLTRVPIIDGTGEATLSQGVLLNGVHVGKSIYVSVTVILNSGSDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTLTQEDGVAKLSINTPSLPITVRTERQATKTMHVLPYNTQGNSKNYLHLSVPNLNVNFHLRTDPDKIRYFTYLIMNKGKLLKVGRQPRESGQVVVVLPLTITTDFIPSFRLVAYYTLAANGQREVVADSVWVDVKDSCVGTLVVTLEIQGDRGARVGLVAVDKGVFVLNKKNKLTQRKIWDVVEKADIGCTPGSGKDFAGVFTDAGLAFKSSKGLQTPQRADLECPKPAARKRRSVQLMEKRMDKLGQYSELRRCCEHGMRDNPMKFSCQRRAQFIQACVKAFLDCCEYILGLARSDLDEEIIPEEDIISRSQFPESWLWTIEEFKDKNGISTKTMNVFLKDSITTWEILAVSLSDKKGICVADPYEVVVKQDFFIDLRLPYSVVRNEQVEIRAILYNYRVELLYNPAFCSLATAKKRHTVPAKSSVPVPYIIVPLKTGLQEVEVKAAVFISDGVKKTLKVVPEGMRVNKTVVTRTLDPEHGQQGVQREIPPADLSDQVPDTESETKILLQGDAIDGDRLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGLEKRQEALELIKKGYTQQLAFRQKNSAFAAFQRLSSTWLTAYVVKVFAMAANLVLCGAVKWLILEKQKPDGVFEENGPVIHQEMIGGFKNEEKDVSLTAFVLIALQEAKDQVNSLLRSINKARDFLAELKRPYTVAIAGYALALSDKFLNKLLNRWEEPGQKLYNVEATSYALLALLVVKDFDSVPPIVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDLNLDVSIHLPSRSRHRILESASLLRSKENERFTLIAEGKGQGTLSVVTMYHAKTKGKTCKKFDLKVSSMVLDICTRYLGQDATMSILDISMMTGFSPDTEDLKLLSTGVDRYISKYELNKALSNKNTLIIYLDKISHEDCISFKVHQYFNVGLIQPGSVKVYSYYNLDESCTRFYHPEKEDGMLNKLCHKEMCRCAEENTLDDRLERACEPGVDYVYKTRLLVIEQIIKSGSVGQERRFISHIKCREALKLKEGGHYLVWGVSSDLWGISYIIGKDTWVELWPDGDVCQDEENQCQDLANFSFGCPN >XP_038284790.1 complement C3 [Canis lupus familiaris] ASGPRLLLLLLLTLPLALFSMITPNILRLENKETVVLEAHDLENTEVTVTVHDFPAKKQVLFDLTSANQYMSVTIQMPADAKSESKFVIVQAAFGALEKVVLVSFQSGYLFIQTDKTIYTPSSTVLYRVFTVDIISIQSPDGVTVKRGSLSSQNDGILSQSYIPELVNMGQWKIQAHYEDAPEQVFSAEFEVKEYVLPSFEVQVEPAQKFYYIDSEGLDVTIMARFLYGKEVDGTAFVIFGVQDGDRRISLSQSLTRILIEDGNGVATLKRNVLLEGVRVGKSLYVSATVILHSGSDMVEAESNAIPIVTSPYQIHFTKTPKFFKPAMPFDLMVFVTNPDGSPAPHVPVGILTQKDGVAKLTINTPPLHITVSTKRQATRTMEVQPYNTIGNSRNYLHLSVPTLNVNFHLRTDPAQIRYYTYLIMNKGKILKVGRQERESGQDLVVLPLTITSDFIPSFRLVAYYTVGSSGQREVVADSVWVDVKDSCMGTLVVTLIIQGDPGARVGLVAVDKGVFVLNKKNKLTQSKIWNVVEAADIGCTAGSGKDYAGVFMDAGLALKTNKELQTPQRRDLECPKPAARRRRSVVLTEKRMDKVGQYPELRKCCEGGMRDNPMKFSCERRAQFVSSCVKAFLECCKYILGLARSDMDEELFLEEDIVSRSQFPESWLWTIEILNEKNGISTKTMNVFLKDSITTWEILAVSLSKKKGICVADPYEVTVLQDFFIDLRLPYSVVRNEQVEIRAILYNYQVELLYNPAFCSLATSKKSYNIPAKSSVAVSYVIVPLKIGLHEVEVKAAVFANDGVKKILKVVPEGILVNQTLAIRTLDPEAGQEGVQREVHAADLGDQVPDTESETRILLQGDAIDGDRLKHLIVTPSGCGEQNMIGMTPTVIALHYLDQTEQWDKFGLEKRQEALELIKKGYTQQLAFRQPNSAFAAFQRPSSTWLTAYVVKVFSLATNLVLCGAVKWLILEKQKPDGIFQEDGPVIHQEMTGGFREEEKSVSLTAFVLIALKEAEDQVNILPSSIEKAGNYLANLRRPYSVAIAGYALAHLDKNLRKFLNRWVEPGKKLYNVEATSYALLALLLLKDFDNVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDLNLQVSINLPSRSKHHIVDSPSLQRSKKNENFEVIAKGKGQGTLSVVTMYYAKLKNKACKKFDLRVDSMTLNICTRYLGEDATMSILDISMMTGFSPDTCDLNQLSSGIERYISKYELNKAFSNKNNVILYLEKISHEDCISFRVHQYFKVGLIQPGSVKVYSYYNLDESCTRFYHPEKEDGQLSKLCHKDMCRCAEENTKDERLDKACEPGVDYVYKTRLLAVEQIIKSGSRGQERRFISHIRCREALKLQDGKRYLVWGVSTDLWGINYIIGKDTWVEMWPEADECQDEENRCQDLASFTFGCPN >XP_008251121.2 PREDICTED: complement C3 alpha chain isoform X1 [Oryctolagus cuniculus] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEVRAVLYNYRVELLYNPAFCSLATAKKNHTIPPKSSLPIPYVLVPLKIGLQEVEVKAAVFISDGVKKTLKVVPEGMPINKTVAVRTLDPENGQGGVQKEIPPADISDQVPGTESETKILLQGDAIDGERLKHLIVTPSGCGEQNMIAMTPTVIAVHYLDHTEQWDKFSLEKRQEALELIKKGYTQQLAFKQPNSAYAAFLRAPSTWLTAYVVKVFSLAVNLVLCGAVKWLIMEKQKPDGVFQEDAPVIHQEMIGGQRNVEKEAALTAFVLIALQEAREQVNSLAASINKSRDFLANLQRPYSVAIAGYALAQQDKFLNKFLNRWEEPGQRLYNVEATSYALLALLLLRDFDSVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDLNMVVSIQLPSRSKHRIVDSASLLRSKENQGFTLTAQGKGQGTLSVVTTYFAKVKGKVCKKFDLRVNTMILDICTRYLGEDATMSILDISMMTGFVPDTDDLNLLSTGVDRYISKYELNKAFSNKNTLIIYLDKISHEECLSFKVHQYFNVGLIQPGAVKVYSYYNLEETCTQFYHPEKEDGMLSKLCHKEMCRCAEENTLNDRLDKACEPGVDYVYKTKLVVVENTIKSGSAGQQRRFISHIKCRDALKLKDGKHYLVWGLSSDLWGTSYIIGKDTWVEFWPEKEECQDEENHCEDLDAFAFGCPN >XP_024092530.1 complement C3 isoform X1 [Pongo abelii] TSGLS-LLLLLLTLPLALYSIITPNILRLESEETVVLEAHGVGDVPVTVTVHDFPGKKLVLSVLTPATSHMGVTFTIPAEFKSENKFVTVQATFGPVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNMVNIENPDGVPVKQDSLSSQNFGILPLSDIPELVNMGQWKIQAYYENSPQQVFSAEFEVKEYVLPSFEVIVEPTEKFYYIYNKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGDAVLSRKVLLDGVQVGKSLYVSVTVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVLTQGDGMAKLSINTHPLSITVRTKEQATRTMQAQPYSTVGNSNNYLHLSVPTLNVNFLLRMDRAKIGYYTYLIMNKGKLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLGASGQREVVADSVWVDVKDSCVGSLVVTLKIEGDHGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSTGQQTAQRAELQCPQPATRRRRSVQLTEKRMDKVGKYPELRKCCEDGMRENRMRFSCQRRTRFISACKKAFLDCCNYMLGLARSNLDEDIIAEENIVSRSEFPESWLWNIEDLKPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRVELLHNPAFCSLATTKRRHTIPAKSSLSVPYVIVPLKTGLQEVEVKAAVFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERGREGVQKDIPPADLSDQVPDTESETRILLQGDAIDAERLKHLIVTPSGCGEQNMISMTPTVIAVHYLDETEQWEKFGPEKRQGALELIKKGYTQQLAFRQPSSAYAAFVRAPSTWLTAYVVKVFSLAVNLVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNEKDMALTAFVLISLQEAKDQVNSLPGSITKAGDFLENLQRSYTVAIAGYALAQMDRLLNKFLNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKELNLDVSLQLPSRSTHRIHESASLLRSKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLCNKFDLKVTTMILEICTRYRGQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHDDCLAFKVHQYFNVELIQPGAVKVYAYYNLAESCTRFYHPEKEDGKLDKLCRDELCRCAEENTLEERLDKACEPGVDYVYKTRLVAIEQIIKSGSVGQQRTFISPIKCREALKLEERKHYLMWGLSSDFWGLSYIIGKDTWVEHWPEEDECQDEENQCQDLGTFTFGCPN >XP_010726629.1 complement C3 [Meleagris gallopavo] LLLPLLLGVLLLHVPT--VTMVTPAVLRLVTDEQVVLEAPGLSPTEANILVQDFPQKRKVLFQLNPAEGMMAATIKVPVLLPQVKHFVSVVARVGQLEKVLLVSLQSGHIFLQTDKPIYTPGSTVLCRLFALSIVEVKTPDNVIIKQVPVSSPKNGIFSINNLPEVVSLGTWTITAKFEDSQDQVFSTQFEVKEYVLPSFEVTLDPQEKFLYIDREDFRVFIKARYLYGKNLQGTAFALFGVMVDDERKTIPQTLQRVKVTDGDGEVVLPMAMLRQ--RVGHSLYVTVTVLTESGSDMVEAQRSGIRIVTSPYTIHFTHTPKYFKPGMPFDLTVYVTNPDNSPAPRIPVKASTQRDGKAKLVLNMPSVPITVRTARQASQQMVAEAYQSQGNSGNYLHLAVGNLPVNFHLKSNRRSVSYFTYLILSKGHIVHVGRQPREGDQSLVTMSLPVTANLIPSFRIVAYYHV---KPGEIVADSVWVDVKDTCMGNLVVRLRIEGDHKAHVGLVAVDKAVYVLN-KNKLTQSQVWDTVEKSDIGCTPGSGRDHVGVFADAGLSLATNVNIKTEQRGEVECAKPAKRKRRSVKLIKYKGTKMAEYNNLRKCCEDGMKENLMGYSCEKRATYILACTDAFLNCCLYIYELARSEADDAFLADEDITSRSLFPESWLWQVEELTNELGISTKTLPIYLKDSITTWEVLAVSLSEKKGLCVADPYEITVMKEFFIDLRLPYSAVRNEQVEVRAILYNYWVELMYNPALCSASTSKTRYQLEPQTSHAVPFVIVPLQLGQHDVEVKAAVFVSDGVKKKLRVVPEGMRLEKTVKIVELDPKTGNNGVQEKVKAANLSDIVPNTESETKVSIQGKAIDGTKLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDSTMQWETFGINRRAEAIELIKKGYTQQLAFRKDDGSFAAFTRPSSTWLTAYVAKVFAMAINMVVCGAIKWLILEKQKPDGLFQEDAPVIHKEMVGGYHGAEPSVSLTAFVLTALQESQKYVKSLDGSIAKASDYLSSLTRPYTVALSSYALALTRKKL--LMTHWAERNAHTYNIEGTSYALLALLQMEKTELTGPVARWLAQQNYFGGGYGSTQATILVFQALAQYHMELNLDVSVLLPRRATYRIESNALVARSKLNEDFTVKAEGTGKGTMTVVTVYNAKVPENECDNFDLRVSSVKITICTRFLDVDATMSILDISMLTGFSPDVQDLKSLSEGVERYISKFEIDHSLSNRSNLIIYLDKISHEECIAFRAHQHFQVGLIQPASVSVYSYYKIDDRCTRFYHPDKDGGQLRKICHGDVCRCAEENTVNERIDLACKPGVDYVYKVKVVTILSVIKMGTLGSNRTFVSHKQCRDALSLQKGQDYLVWGLASDLWVFSYLIGKDTWLEAWPLEESCQDADLLCQDFIEFSFGCPS >XP_017906433.1 PREDICTED: LOW QUALITY PROTEIN: complement C3 [Capra hircus] TSGPSLLLLLLLALPMALYSMITPNILRLESEETVVLEAHGGGNIQVSVTVHDFPAKKQVLSQLNSNNGYLSVIIKIPAELKSEHKFVIVVATFGNVEKVVLISLQSGYLFIQTDKTIYTPGSSVLYRVFTVDFISIETPDGVLVKQDSLSSHNFGILALSNIPELVNMGVWKIKAHYEDSPQQVFSTEFEVKEYVLPSFEVQLEPEEKFYYVDDDGLKINIIARFLYGEQXDGTAFVIFGVQDGDRRISLTHSLTRVPINDGNGEAILKRQVLLNGVQVGKSIYVSATVILQSGSDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTLTQDDGVAKLSINTQPLTITVRTKRQATRTMQALPYNTQGNSNNYLHLSVPTLNVNFHLRTDPAKIHYYTYMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLNANGQREVVADSVWVDVKDSCMGTLVVTLKIEANHGSRVWLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLTFKTSQGLETQQRSDPQCPKPAARRRRSVQLMEKRMDKVGQYSDLRKCCEDGMRDNPMKFPCQRRAQFILACVKAFLDCCEYILELARSDLDDEIIPEEDIISRSQFPESWLWIIDDFKDKNGISTKLTKVFLKDSITTWEILAVSLSDKKGICVADPYEITVMQDFFIDLRLPYSVVRNEQVEIRAILYNYRVELLYNPAFCSLATAKKRHMIPARSSVAVPYVIVPLKVGLHEVEVKAAVFISDGVKKTLKVVPEGIRVNKTVAIRTLNPEYGQDGVQREVPAADLSDRVPDTESETKILLQGDAIDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGVEKRQEALELIRKGYTQQLAFRQKSSAYAAFQRPPSTWLTAYVVKVFALSANLDLCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFKDREKDVSLTAFVLIALHEAKDQVNSLGRSITKAGNFLEELRRPYTVAIAAYALALLGKRLTKFLNRWEEPNKKLYNVEATSYALLALLARKDFDTVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKELNLDVSIHLPSRNKHRILESASLLRSKENEPFTVRAEGKGQGTLSVVTMYHAKLKGKVCKKFDLRVSSMILDICTKYLGQDATMSILDISMMTGFSPDIDDLKLLSTGVDRYISKYEMNRD-SNKNTLIIYLDKVSHEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCHCAEENTLEDRLDRACEPGVDYVYKTRLLVIEQIIKSGSVKQERKFISHIKCREALKLKEGAHYLVWGVSSDLWGISYIIGKDTWVELWPEAEECQDEENQCEDLASFTFGCPN >XP_034802768.1 complement C3 [Pan paniscus] TSGPS-LLLLLLTLPLALYSIITPNILRLESEETVVLEAHDAGDVPVTVIVHDFPGKKLVLSVLTPATNHMGVTFMIPAEFKSENKFVTVQATFGAVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNMVNIENPEGIPVKQDSLSSQNFGILPLSDIPELVNMGQWKIQAYYENSPQEVFSAEFEVKEYVLPSFEVIVEPTEKFYYIYNKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRILIEDGSGEVVLSRKVLLEGVQVGKSLYVSVTVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVLTQGDGVAKLSINTHPLSITVRTKEQATSTMQALPYSTVGNSNNYLHLSVPTLNVNFLLRMDRAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLGASGQREVVADSVWVDVKDSCVGSLVVTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVLLTEKRMDKVGKYPELRKCCEDGMRENPMRFSCQRRTRFISACKKVFLDCCNYILGLARSDLDEDIIAEENIVSRSEFPESWLWNVEDLKPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRVELLHNPAFCSLATTKRRHTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERGREGVQKDIPPADLSDQVPDTESETRILLQGDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVRAPSTWLTAYVVKVFSLAVNLVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNEKDMALTAFVLISLQEAKDQVNSLPGSITKAGDFLENLQRSYTVAIAGYALAQMGRLLNKFLNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKELNLDVSLQLPSRSTHRIHESASLLRSKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLCNKFDLKVTTMILEICTRYRGQDATMSILDISMMTGFAPDTDDLKQLASGVDRYISKYELDKAFSDRNTLIIYLDKVSHDDCLAFKVHQYFNVELIQPGAVKVYAYYNLAESCTRFYHPEKEDGKLNKLCRDELCRCAEENTLEERLDKACEPGVDYVYKTRLVAIEQTIKSGSVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGLSYIIGKDTWVEHWPEEDECQDEENQCQDLGAFTFGCPN >XP_018871079.1 complement C3 [Gorilla gorilla gorilla] TSGPS-LLLLLLTLPLALYSIITPNILRLESEETVVLEAHDAGDVPVIVTVHDFPGKKLVLSVLTPATNHMGVTFTIPAEFKSENKFVTVQATFGAVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNMVNIENPEGIPVKQDSLSSQNFGILPLSDIPELVNMGQWKIRAYYENSPQQVFSAEFEVKEYVLPSFEVIVEPTEKFYYIYNKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQVGKSLYVSVTVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVLTQGDGVAKLSINTHPLSITVRTKEQATRTMQALPYSTVGNSNNYLHLSVPTLNVNFLLRMDRAKIRYYTYLIMNKGRLLKAGRQMREPGQDLVVLPLSITTDFIPSFRLVAYYTLGASGQREVVADSVWVDVKDSCVGSLVVTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVQLTEKRMDKVGKYPELRKCCEDGMRENPMRFSCQRRTRFISACKKVFLDCCNYILGLARSNLDEDIIAEENIVSRSEFPESWLWNVEDLKPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRVELLHNPAFCSLATTKRRHTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVFISDGVRKSLKVVPEGFRMNKTVAVRTLDPERGREGVQKDIPPADLSDQVPDTESETRILLQGDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQAALELIKKGYTQQLAFRQPSSAFAAFVRAPSTWLTAYVVKVFSLAVNLVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNEKDMALTAFVLISLQEAKDQVNSLPGSITKAGDFLENLQRSYTVAIAGYALAQMGRLLNKFLNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKELNLDVSLQLPSRSTHRIHESASLLRSKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLCNKFDLKVTTMILEICTRYRGQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHDDCLAFKVHQYFNVELIQPGAVKVYAYYNLAESCTRFYHPEKEDGKLNKLCRDELCRCAEENTLEERLDKACEPGVDYVYKTRLVAIEQTIKSGSVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGLSYIIGKDTWVEHWPEEEECQDEENQCQDLGAFTFGCPN >XP_021136840.1 complement C3 [Columba livia] -------------EMRSRVTMVAPAVLRLDTEEQVVLEAPGLVATEATLLVQDFPGKRQVLYPINPAQGMLAATIKVSAALPPAKRFVSVTARVAQLEKVLLVSLQSGHIFVQTDKPIYTPSSTVLCRLFALDVVEFKTPDNIIVKQVPVSSPMTGIFSLNYLPEVVSLGTWTIMAKFEDSPEQVFSTQFEVKEYVLPSFEVLLEPEEKFLYIDREDFRVTVTARYLYGKHLQGSAFVLFGVMVDDEKKSIPQSLQRIQVTDGDGEAILSMADLRQ--RVGHSLYVSVTVLTDSGSDMVETQRSGIHIVTSPYTIHFTHTPKYFKPGMPFDLTVYVTNPDGSPAPRVTVKASTQRDGTAKLVLNMPTVPITVRTDRQASRQMTAEAYRSQGSSGNFLHLAVGNLVVNFHLKSSSDAVRFFTYLIMSKGRIVRVGRQAHEAGQSLVTMSLPVTAELIPSFRIVAYYYV---MPSEIVADSVWVDVKDTCMGSLVVRLRIEGDHKAHVGLVAVDKGVFVLNKKHKITQAKVWDTVEKSDIGCTAGSGRDNVGVFADAGLSIVTSEKVTTPQRAEVQCPQPAKRKRRSLQLMEYKGTKAAEYTAQRKCCEDGMKDNPMGHSCERRATYIQTCVQAFLTCCNYILQLARSEVDDGFLDDDDIPSRSLFPESWLWQEETLTNDLGISGKTLPIYLKDSITTWEVLAVSLSPTKGLCVADPYEITVMKEFFIDLRLPYSVVRNEQVEIRAVLYNYWVELVHNPAICSASTSKTRYKLKPQSSWAVPFVIVPLQLGQHDVEVKAAVFVADGVKKKLKVVPEGIRLEKTVKIVELDPKTGINGVQERVRAANLSDIVPNTESETKVSIQGKAIDGDKLKHLIVTPAGCGEQNMIGMTPTVIATHYLDSTQQWESFGIDRRAEAINLIKKGYTQQLAFRKPDNSYAAFKRPSSTWLTAYVAKVFSLAITLVVCGAVKWLILEKQKPDGIFQEDAPVIHKEMVGGYQGAEPEVSLTAFVLIALQESRERVNSLERSITKAAQYLTSLARPYTVALTSYALALTGHKV--LMKSWEERNARTYNMEGTSYALLALLQMEKAELTGPVARWLAQQNYFGGGYGSTQATMLVFQALAQYQLELNLDVSLLLPRRATYRIERNALVARSKLNEDFTVKAEGTGKGTMTVVTVYNAKVPEKDCDNFDLRVQSVKITICTRHLDVDATMSILDVSMLTGFSPDLQDLKRLTEGVDRYISKFEIDKALAERSNLVIYLDKISHEECFAFKAHQRFRVGLIQPAAVTVYSYYKIDDRCTRFYHPDKDGGQLSKICYGDICRCAEENTVNQRIERACEAGVDYVYKVKLVTVLSVIKTGTAGGNRTFVSHRQCRDALQLRLGQEYLVWGLASDMWVFSYLVGKDTWLELWPSEDACQEPDLLCQDLLDFAFGCPS >XP_006023407.1 complement C3 [Alligator sinensis] EGSICYLAAVLLFFPAVVYSLIIPNVLRVESEEKVVVEANGLAVTEVTITVHDFPFKRQVLYNLNPDEGMLTATIKISSVKKDSNQYVLIQAKIKDLEKVVLLSFHSGYIFVQTDKTIYTPGSTVLCRIFAMGIVEFETPEGIIVKQSPVFSPMTGIYSLNNLPEIVNLGTWKVVAKFQDSPLQNFSTQFEVKEYVLPSFEVILEPSEKFLYIDDKDFRVSITARYLYGKKLEGTAFVLFGVKMENEKRSIPQSLKRIQIQDGDGEAVLTRGMLQA--RVGHTLYISVTVLTESGSDMVEAERTGIHIVTSPYQIHFTKTPKYFKPGMPFELMVYVTNPDGSPAPRVPVKASTQGNGMAKLILNMPRVKVTVRTVRQASQSMVAEAYKTQGGTKNYLHLAVTNLPVNFHLKTDNNGLKHFSYLILNKGKIVQAGRQLRQAGQNLVSMPLPITPDLVPSFRIVAYYQV---GSSEMVADSVWVDVKDTCMGTLVVKIKVEGDYKAHVGLVAVDKGVYVLNKKFKFTQSKIWDTVEKSDIGCTAGGGRDNLGVFADAGLALQTNT-ISTPQRTEFDCPQPASRKRRSVQLIEHKASKVANYHKLKKCCEDGMYENPMGHSCDKRAVYIQECVAAFLDCCKYILELARSEVDEGFLSDDDITSRSLFPESWLWQVEQLTNNMGISTKTIPVFLKDSITTWEVLAVSLSENKGICVANPYEITVMKDFFIDLRLPYSVVRNEQVEIRAILYNYWVELIHNPAFCSASTSKQRYDLPRLSSLAVPLVIVPLELGLHDVEVKAAVFVADGVKKKLKVVPEGMRMTKTVKSVTLEPSVGLGGVQVQVTAADIEDIVPNTESETRVSVQGKSIDGANVKHLIVTPSGCGEQNMIGMTPTVIATHYLDSTNQWDKVGVDRRNEAIRLINQGYTQQLVYKKGDFSYSAFQRESSTWLTAYVAKVFAMATSLVLCGAVKWLILEKQKPDGVFQEDGPVIHGEMVGGYKGAEPEVSLTAFVLIALHESKDHINSLEGSINKAAEFLSFLKRPYTIALTSYALALVEKKV--LMNHWEEKGARTFNIEGTSYGLLALLKMKKFELTGPIVRWLTEQKYYGGGYGSTQATILVFQALSQYQSELQLDVSILLPRRAKIRIESNAFLSRSKWNENFTVRAEGTGQGTLTVVTVYNAKIKEDECKKFYLSVSSVKINICTRFLGVDATMSIIDVSMLTGFSPDTDDLKRLSQGVDRYISKFEMDKAPSERASLIIYLDKVSHEECLSFKAHQFFEVGLIQPASVTVYDYYTIDDRCTKFYHPSKQSGLLSKICHGDVCRCAEENTLDKRIEDACEPGVDYVYKTRLVEILTIIKAGTVGQRRKFISHVKCRESLNLEQNKDYLIWGLSSDLWTLSYIISKDTWIEKWPNEEECQEPDFLCQEFQEFSFGCPT >XP_006265663.2 PREDICTED: complement C3 [Alligator mississippiensis] EGSICYLAAVLLFFPAVVYSLITPNVLRVESEEKVVVEANGLAATEVTITVHDFPFKRQVLYNLNPDEGMLTATIKISSVKKDSNQYVLIQAKIKDLEKVVLLSFHSGYIFVQTDKTIYTPGSTVLCRIFAMGIVEFETPEGIIVKQSPVFSPMTGIYSLNNLPEIVNLGTWKVVAKFQDSPLQNFSTQFEVKEYVLPSFEVILEPSEKFLYIDDKDFRVSITARYLYGKKLEGTAFVLFGVKMENEKRSIPQSLKRIQIQDGDGEAVLTRGMLQA--RVGHTLYISVTVLTESGSDMVEAERTGIHIVTSPYQIHFTKTPKYFKPGMPFELMVYVTNPDGSPAPRVPVKASTQGNGMAKLILNMPRVKVTVRTVRQASQSMVAEAYKTQGGTKNYLHLAVTNLPVNFHLKTDNNGLKHFSYLILNKGKIVQAGRQLRQAGQNLVSMPLPITPDLVPSFRIVAYYQV---GSSEIVADSVWVDVKDTCMGTLVVKIKVEGDYKAHVGLVAVDKGVYVLNKKFKFTQSKIWDTVEKSDIGCTAGGGRDNLGVFVDAGLALQTNT-ISTPQRTEFDCPQPASRKRRSVQLIEHKASKVANYHKLKKCCEDGMYENPMGHSCDKRAMYIQECVAAFLDCCKYILELARSEVDEGFLSDDDITSRSLFPESWLWQVEQLTNNMGISTKTIPVFLKDSITTWEVLAVSLSENKGICVADPYEITVMKDFFIDLRLPYSVVRNEQVEIRAILYNYWVELIHNPAFCSASTSKQRYDLPRLSSLAVPLVIVPLELGLHDVEVKAAVFVADGVKKKLKVVPEGMRMTKTVKSVTLEPSVGLGGVQVQVTAADIEDIVPNTESETRVSVQGKSIDGANVKHLIVTPSGCGEQNMIGMTPTVIATHYLDSTNQWDKVGVDRRNEAIRLINQGYTQQLVYKKGDFSYSAFQRESSTWLTAYVAKVFAMATSLVLCGAVKWLILEKQKPDGVFQEDGPVIHGEMVGGYKGAEPEVSLTAFVLIALHESKDHINSLEGSINKAAEFLSFLKRPYTIALTSYALALVEKKV--LMNHWEEKGARTFNIEGTSYGLLALLKMKKFELTGPIVRWLTVQKYYGGGYGSTQATILVFQALAQYQSELQLDVSILLPRRAKIRIESNAFLSRSKWNENFTVRAEGTGQGTLTVVTVYNAKIKEDECKKFDLRVSSVKINICTRFLGVDATMSIIDVSMLTGFSPDTDDLKRLSQGVDRYISKFEMDKAPSERASLIIYLDKVSHEECLSFKAHQFFEVGLIQPASVTVYDYYTIDDRCTKFYHPSKQSGLLSKICHGDVCRCAEENTLDKRIEDACEPGVDYVYKTRLVEILTIIKAGTVGQRRKFISHVKCRESLNLEQNKDYLIWGLSSDLWTLSYIISKDTWIEKWPNEEECQEPDFLCQEFQEFSFGCPT >XP_020772460.1 complement C3 [Odocoileus virginianus texanus] TSGPSLLLLLLLALPMALYSMITPNILRLESEETVVLEAHGGGDIPVSVTVHDFPAKRQVLSQLNNGNGYLAVTIKIPAELKSDHKFVTILATFGGVEKVVLISLQSGYLFIQTDKTIYTPGSTVLYRVFTVDIVSIETPDGIPVKRDSQSSHNFGILALSNIPELVNMGVWKIKAHYEDSPQQVFSADFEVKEYVLPSFEVQLEPEEKFYYVDDDGLKINIIARFLYGEHVDGTAFVIFGVQDGDRRISLTHSLTRVPIIDGNGEAILRRQVLLNGVQVGKSIYVSATVILQSGSDMVEAERTGIPIVTSPYQIHFTKTPKFFKPAMPFDLMVYVTNPDGSPARHIPVVTLTQDDGVAKLSINTQPLTITVRTKRQATKTMQALPYNTQGNSNNYLHLSVTTLNVNFHLRTDPAKIRYYTYMIMNKGKLLKVGRQDREPGQDLVVLPLTITSDFIPSFRLVAYYTLNANGQREVVADSVWVDVKDSCMGTLVVTLKIEADQGARVGLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGRDYAGVFTDAGLALKTSQGLETKQRADPLCPQPAVRRRRSVQLMEKRMDKVGQYSDLRKCCEDGMRDNPMKFPCQRRAQFILACVKAFLDCCEYILELARSDLDDEIIPEEDIISRSQFPESWLWTIEDFKDKNGISTKLTNVFLKDSITTWEILAVSLSDKKGICVADPYEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRVELLYNPAFCSLATAKKRHVIPARSSLAVPYVIVPLKVGLHEVEVKAAVFISDGVKKTLKVVPEGIRVNKTVAIQTLNPEHGQGGVQREVPAADLSDQVPDTESETKILLQGDAIDGERLKHLIQTPSGCGEQNMIGMTPTVIAVHYLDSTEQWEKFGLEKRQQSLELIRKGYTQQLAFRQKNSAYAAFLRPASTWLTAYVVKVFALSANLDLCETVKWLILEKQKPDGIFQEDGPVIHQEMIGGFKDREKDVSLTAFVLIALHEAKDQVNSLGRSINKAGDFLEELRRPYTVAIAAYALALLGKRLTKFLNRWEEPNQKLYNVEATSYALLALLARKDYDTVAPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDLNLDVSIQLPSRNKHRILESASLLRSKENERFTVRAEGKGQGTLSVVTVYHAKLKGKVCKKFDLQVSSMILDICTRYLGQDATMSILDISMMTGFSPDIDDLKLLSSGVDRYISKYEMNKD-SNKNTLIIYLDKVSHEDCLSFKVHQYFNVGLIQPGAVKVYSYYNLDETCIRFYHPDKEDGMLSKLCHKDTCRCAEENTLDGRLDKACEPGVDYVYKTRLTVIEQIIKSGSVNQERKFISHIKCREALKLKEGAHYLVWGVSSDLWGISYIVGKDTWVELWPDAEECQDEENQCEELANFTFGCPN
PhyML tree of selected proteins ((((XP_030274930_1_complement_C3_like__Sparus_aurata_:0.11204528,(NP_001098552_1_complement_component_C3_1_precursor__Oryzias_latipes_:0.16138686,XP_015824898_1_PREDICTED__complement_C3__Nothobranchius_furzeri_:0.21015373):0.06262684):0.30317198,(tr_B8JKW4_B8JKW4_DANRE_Complement_component_c3a__duplicate_1_OS_Danio_rerio_OX_7955_GN_c3a_1_PE_1_SV_1:0.16358924,tr_F1QX13_F1QX13_DANRE_Complement_component_c3a__duplicate_3_OS_Danio_rerio_OX_7955_GN_c3a_3_PE_1_SV_1:0.23116417):0.27930905):0.23347634,((((XP_021136840_1_complement_C3__Columba_livia_:0.10198224,(XP_010726629_1_complement_C3__Meleagris_gallopavo_:0.03282429,NP_990736_3_complement_C3__Gallus_gallus_:0.02916902):0.1001722):0.17057539,(XP_006265663_2_PREDICTED__complement_C3__Alligator_mississippiensis_:0.00133348,XP_006023407_1_complement_C3__Alligator_sinensis_:0.0057325):0.16418844):0.13511946,((((NP_033908_2_complement_C3_preproprotein__Mus_musculus_:0.05876654,NP_058690_2_complement_C3_precursor__Rattus_norvegicus_:0.02112739):0.08484209,(XP_008251121_2_PREDICTED__complement_C3_alpha_chain_isoform_X1__Oryctolagus_cuniculus_:0.09888644,(XP_024092530_1_complement_C3_isoform_X1__Pongo_abelii_:0.01362131,((XP_024207219_1_complement_C3__Pan_troglodytes_:0.00071449,XP_034802768_1_complement_C3__Pan_paniscus_:0.00071284):0.00591697,(XP_018871079_1_complement_C3__Gorilla_gorilla_gorilla_:0.00359261,NP_000055_2_complement_C3_preproprotein__Homo_sapiens_:0.00646115):0.00052912):0.00829513):0.11083814):0.0204506):0.03308471,(XP_020936478_1_complement_C3_isoform_X1__Sus_scrofa_:0.07862792,((NP_001035559_2_complement_C3_preproprotein__Bos_taurus_:0.02421718,(XP_027825575_2_complement_C3__Ovis_aries_:0.00472708,XP_017906433_1_PREDICTED__LOW_QUALITY_PROTEIN__complement_C3__Capra_hircus_:0.01402511):0.0146969):0.00961702,(XP_020772460_1_complement_C3__Odocoileus_virginianus_texanus_:0.00989724,((KAB0363358_1_hypothetical_protein_FD754_007514__Muntiacus_muntjak_:0.0014198,KAB0388260_1_hypothetical_protein_FD755_003216__Muntiacus_reevesi_:0.00141788):0.0029162,(OWK12416_1_C3__Cervus_elaphus_hippelaphus_:0.02635624,(KAF4014700_1_hypothetical_protein_G4228_005895__Cervus_hanglu_yarkandensis_:0.01159174,XP_043322320_1_complement_C3__Cervus_canadensis_:0.00070882):0.00000001):0.00349016):0.00237351):0.01589451):0.06924861):0.0335972):0.02153405,(XP_038284790_1_complement_C3__Canis_lupus_familiaris_:0.13052548,XP_023100060_1_complement_C3_like__Felis_catus_:0.16065882):0.02235564):0.29204321):0.06532392,(XP_018109218_1_complement_C3__Xenopus_laevis_:0.24066813,XP_040202590_1_complement_C3_like__Rana_temporaria_:0.56297235):0.18966528):0.22170342):0.1684463,tr_A5PMP6_A5PMP6_DANRE_Complement_component_c3b__tandem_duplicate_1_OS_Danio_rerio_OX_7955_GN_c3b_1_PE_4_SV_1:0.90075826,(XP_006565503_2_alpha_2_macroglobulin_like_protein_1_isoform_X1__Apis_mellifera_:2.35993204,(XP_039271128_1_complement_C3_like__Styela_clava_:1.62166008,(CAE1304902_1_unnamed_protein_product__Sepia_pharaonis_:1.62576069,(XP_031565662_1_complement_C3_like__Actinia_tenebrosa_:1.1707229,(XP_038046850_1_complement_C3_like_isoform_X2__Patiria_miniata_:0.86261282,XP_030852887_1_complement_C3__Strongylocentrotus_purpuratus_:1.17968021):0.19751957):0.15806821):0.17094529):0.13617872):0.4638959);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)