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PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0025 | P02751 | Fibronectin 1 | FN1 | CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF, SMDCF | Homo_sapiens | Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). |
Domains | Gene Ontology |
PF00039 (12_fn1) PF00040 (2_fn2) PF00041 (17_fn3) |
GO:0002020 (enables) protease binding
GO:0005102 (enables) signaling receptor binding GO:0005178 (enables) integrin binding GO:0005201 (enables) extracellular matrix structural constituent GO:0005515 (enables) protein binding GO:0005518 (enables) collagen binding GO:0008022 (enables) protein C-terminus binding GO:0008201 (enables) heparin binding GO:0016504 (enables) peptidase activator activity GO:0019899 (enables) enzyme binding GO:0042802 (enables) identical protein binding GO:0043394 (enables) proteoglycan binding GO:0051087 (enables) chaperone binding GO:0097718 (enables) disordered domain specific binding GO:0001525 (involved in) angiogenesis GO:0001932 (involved in) regulation of protein phosphorylation GO:0006953 (involved in) acute-phase response GO:0007044 (involved in) cell-substrate junction assembly GO:0007155 (involved in) cell adhesion GO:0007160 (involved in) cell-matrix adhesion GO:0007161 (involved in) calcium-independent cell-matrix adhesion GO:0007229 (involved in) integrin-mediated signaling pathway GO:0007399 (involved in) nervous system development GO:0007507 (involved in) heart development GO:0008284 (involved in) positive regulation of cell population proliferation GO:0008360 (involved in) regulation of cell shape GO:0009611 (involved in) response to wounding GO:0010628 (involved in) positive regulation of gene expression GO:0010952 (involved in) positive regulation of peptidase activity GO:0014068 (involved in) positive regulation of phosphatidylinositol 3-kinase signaling GO:0018149 (involved in) peptide cross-linking GO:0033622 (involved in) integrin activation GO:0034446 (involved in) substrate adhesion-dependent cell spreading GO:0035987 (involved in) endodermal cell differentiation GO:0042060 (involved in) wound healing GO:0045773 (involved in) positive regulation of axon extension GO:0048146 (involved in) positive regulation of fibroblast proliferation GO:0051702 (involved in) biological process involved in interaction with symbiont GO:0070372 (involved in) regulation of ERK1 and ERK2 cascade GO:0070527 (involved in) platelet aggregation GO:0071635 (involved in) negative regulation of transforming growth factor beta production GO:0072378 (involved in) blood coagulation, fibrin clot formation GO:0150102 (involved in) negative regulation of monocyte activation GO:1901166 (involved in) neural crest cell migration involved in autonomic nervous system development GO:1904237 (involved in) positive regulation of substrate-dependent cell migration, cell attachment to substrate GO:0005576 (located in) extracellular region GO:0005604 (located in) basement membrane GO:0005615 (located in) extracellular space GO:0005788 (located in) endoplasmic reticulum lumen GO:0005793 (located in) endoplasmic reticulum-Golgi intermediate compartment GO:0005886 (located in) plasma membrane GO:0016324 (located in) apical plasma membrane GO:0031012 (located in) extracellular matrix GO:0031093 (located in) platelet alpha granule lumen GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome GO:0072562 (located in) blood microparticle GO:0005577 (part of) fibrinogen complex |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |