PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0022 | Q9Y4K0 | lysyl oxidase like 2 | LOXL2 | LOR, LOR2, WS9-14, Lysyl oxidase homolog 2 | Homo_sapiens | Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation (By similarity). |
Domains | Gene Ontology |
PF00530 (4_SRCR) PF01186 (Lysyl_oxidase) |
GO:0062023 (colocalizes with) collagen-containing extracellular matrix
GO:0004720 (enables) protein-lysine 6-oxidase activity GO:0005044 (enables) scavenger receptor activity GO:0005507 (enables) copper ion binding GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0009055 (enables) electron transfer activity GO:0016491 (enables) oxidoreductase activity GO:0016641 (enables) oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0046872 (enables) metal ion binding GO:0070492 (enables) oligosaccharide binding GO:0000122 (involved in) negative regulation of transcription by RNA polymerase II GO:0001666 (involved in) response to hypoxia GO:0001837 (involved in) epithelial to mesenchymal transition GO:0001935 (involved in) endothelial cell proliferation GO:0002040 (involved in) sprouting angiogenesis GO:0006325 (involved in) chromatin organization GO:0006464 (involved in) cellular protein modification process GO:0006897 (involved in) endocytosis GO:0007155 (involved in) cell adhesion GO:0007568 (involved in) aging GO:0010718 (involved in) positive regulation of epithelial to mesenchymal transition GO:0018057 (involved in) peptidyl-lysine oxidation GO:0022900 (involved in) electron transport chain GO:0030199 (involved in) collagen fibril organization GO:0032332 (involved in) positive regulation of chondrocyte differentiation GO:0043542 (involved in) endothelial cell migration GO:0045892 (involved in) negative regulation of transcription, DNA-templated GO:0046688 (involved in) response to copper ion GO:0070828 (involved in) heterochromatin organization GO:1902455 (involved in) negative regulation of stem cell population maintenance GO:0000785 (located in) chromatin GO:0005576 (located in) extracellular region GO:0005604 (located in) basement membrane GO:0005615 (located in) extracellular space GO:0005634 (located in) nucleus GO:0005654 (located in) nucleoplasm GO:0005694 (located in) chromosome GO:0005783 (located in) endoplasmic reticulum GO:0016020 (located in) membrane |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |