PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0012 | P06702 | S100 calcium binding protein A9 | S100A9 | MIF, NIF, P14, CAGB, CFAG, CGLB, L1AG, LIAG, MRP14, 60B8AG, MAC387, S100-A9 | Homo_sapiens | The iNOS-S100A8/A9 transnitrosylase complex is proposed to also direct selective inflammatory stimulus-dependent S-nitrosylation of multiple targets such as ANXA5, EZR, MSN and VIM by recognizing a [IL]-x-C-x-x-[DE] motif (PubMed:25417112). |
Domains | Gene Ontology |
PF01023 (S_100) |
GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0008017 (enables) microtubule binding GO:0008270 (enables) zinc ion binding GO:0016209 (enables) antioxidant activity GO:0035662 (enables) Toll-like receptor 4 binding GO:0046872 (enables) metal ion binding GO:0048306 (enables) calcium-dependent protein binding GO:0050544 (enables) arachidonic acid binding GO:0050786 (enables) RAGE receptor binding GO:0002376 (involved in) immune system process GO:0002523 (involved in) leukocyte migration involved in inflammatory response GO:0002544 (involved in) chronic inflammatory response GO:0006914 (involved in) autophagy GO:0006915 (involved in) apoptotic process GO:0006919 (involved in) activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006935 (involved in) chemotaxis GO:0006954 (involved in) inflammatory response GO:0007267 (involved in) cell-cell signaling GO:0010976 (involved in) positive regulation of neuron projection development GO:0014002 (involved in) astrocyte development GO:0018119 (involved in) peptidyl-cysteine S-nitrosylation GO:0030307 (involved in) positive regulation of cell growth GO:0030593 (involved in) neutrophil chemotaxis GO:0032119 (involved in) sequestering of zinc ion GO:0032496 (involved in) response to lipopolysaccharide GO:0035425 (involved in) autocrine signaling GO:0035606 (involved in) peptidyl-cysteine S-trans-nitrosylation GO:0035821 (involved in) modulation of process of other organism GO:0042742 (involved in) defense response to bacterium GO:0045087 (involved in) innate immune response GO:0045113 (involved in) regulation of integrin biosynthetic process GO:0050729 (involved in) positive regulation of inflammatory response GO:0050832 (involved in) defense response to fungus GO:0051092 (involved in) positive regulation of NF-kappaB transcription factor activity GO:0051493 (involved in) regulation of cytoskeleton organization GO:0061844 (involved in) antimicrobial humoral immune response mediated by antimicrobial peptide GO:0070488 (involved in) neutrophil aggregation GO:0098869 (involved in) cellular oxidant detoxification GO:2001244 (involved in) positive regulation of intrinsic apoptotic signaling pathway GO:0005615 (is active in) extracellular space GO:0005634 (is active in) nucleus GO:0005737 (is active in) cytoplasm GO:0005576 (located in) extracellular region GO:0005654 (located in) nucleoplasm GO:0005829 (located in) cytosol GO:0005856 (located in) cytoskeleton GO:0005886 (located in) plasma membrane GO:0016020 (located in) membrane GO:0030054 (located in) cell junction GO:0034774 (located in) secretory granule lumen GO:0070062 (located in) extracellular exosome GO:0062023 (part of) collagen-containing extracellular matrix |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |