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PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0010 | P02792 | Ferritin light chain | FTL | LFTD, NBIA3 | Homo_sapiens | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. |
Domains | Gene Ontology |
PF00210 (Ferritin) |
GO:0005506 (enables) iron ion binding
GO:0005515 (enables) protein binding GO:0008198 (enables) ferrous iron binding GO:0008199 (enables) ferric iron binding GO:0042802 (enables) identical protein binding GO:0046872 (enables) metal ion binding GO:0006826 (involved in) iron ion transport GO:0006879 (involved in) cellular iron ion homeostasis GO:0006880 (involved in) intracellular sequestering of iron ion GO:0055072 (involved in) iron ion homeostasis GO:0005737 (is active in) cytoplasm GO:0005576 (located in) extracellular region GO:0005829 (located in) cytosol GO:0016020 (located in) membrane GO:0035578 (located in) azurophil granule lumen GO:0044754 (located in) autolysosome GO:0070062 (located in) extracellular exosome GO:0008043 (part of) intracellular ferritin complex |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |