![]() |
PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0008 | P02743 | Serum amyloid P-component | APCS | SAP, PTX2, HEL-S-92n | Homo_sapiens | Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. |
Domains | Gene Ontology |
PF00354 (Pentaxin) |
GO:0001849 (enables) complement component C1q complex binding
GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0030169 (enables) low-density lipoprotein particle binding GO:0030246 (enables) carbohydrate binding GO:0042802 (enables) identical protein binding GO:0046790 (enables) virion binding GO:0046872 (enables) metal ion binding GO:0051082 (enables) unfolded protein binding GO:0002674 (involved in) negative regulation of acute inflammatory response GO:0006457 (involved in) protein folding GO:0006953 (involved in) acute-phase response GO:0006958 (involved in) complement activation, classical pathway GO:0044793 (involved in) negative regulation by host of viral process GO:0044869 (involved in) negative regulation by host of viral exo-alpha-sialidase activity GO:0044871 (involved in) negative regulation by host of viral glycoprotein metabolic process GO:0045087 (involved in) innate immune response GO:0045656 (involved in) negative regulation of monocyte differentiation GO:0046597 (involved in) negative regulation of viral entry into host cell GO:0048525 (involved in) negative regulation of viral process GO:0051131 (involved in) chaperone-mediated protein complex assembly GO:0061045 (involved in) negative regulation of wound healing GO:1903016 (involved in) negative regulation of exo-alpha-sialidase activity GO:1903019 (involved in) negative regulation of glycoprotein metabolic process GO:0005615 (is active in) extracellular space GO:0005576 (located in) extracellular region GO:0005634 (located in) nucleus GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome GO:0072562 (located in) blood microparticle |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |