PB0005

DATABASE

Click here to access PB0005 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0005	P21810	Biglycan	BGN	PGI, MRLS, DSPG1, PG-S1, SEMDX, SLRR1A	Homo_sapiens	May be involved in collagen fiber assembly.

Domains

Gene Ontology

PF01462 (LRRNT) PF13855 (3_LRR_8)

GO:0005201 (enables) extracellular matrix structural constituent GO:0005515 (enables) protein binding GO:0005539 (enables) glycosaminoglycan binding GO:0030021 (enables) extracellular matrix structural constituent conferring compression resistance GO:0050840 (enables) extracellular matrix binding GO:0008150 (involved in) biological_process GO:0019800 (involved in) peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan GO:0060348 (involved in) bone development GO:0061975 (involved in) articular cartilage development GO:0005615 (is active in) extracellular space GO:0005576 (located in) extracellular region GO:0005796 (located in) Golgi lumen GO:0009986 (located in) cell surface GO:0030133 (located in) transport vesicle GO:0031012 (located in) extracellular matrix GO:0042383 (located in) sarcolemma GO:0043202 (located in) lysosomal lumen GO:0070062 (located in) extracellular exosome GO:0062023 (part of) collagen-containing extracellular matrix

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P21810|PGS1_HUMAN Biglycan OS=Homo sapiens OX=9606 GN=BGN PE=1 SV=2 MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYS AMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV LVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFS GLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNK IQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLK LLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLA IQFGNYKK >tr|Q6GMI5|Q6GMI5_DANRE Biglycan OS=Danio rerio OX=7955 GN=bgna PE=2 SV=1 MLSVCVAFLFLCTAHLPIYSSALPFEQKGFWDFGKDIDVKELMMMMDQEEGSAVEPYKPE HPTCPFGCRCELRVVQCSDLGLGYVPYDIPADTLLLDLQSNRITEIREGDFKGLSNLYAL VLRYNQISKIHPKAFLPLKRLQKLYISHNLLTSMPKNLPSSLVELRIHDNRIKKVPAFSF SGLHNMHVIEMGRNPLQNSGFEPGAFMGLKLNYLRISEAKLTGVPKDLPGSLHELHLDNN QIQAIELVDLSQYTQLQRLGLGSNQIRHIEHGALSYLTNLRELHLDNNRLPSVPSGLSHM KYLQVVYLHSNNITNVGEDDFCPTGFGLKKVFYNGISLFDNPIRYWEVQPSTFRCVSDQM AVQFGNHKK >tr|B7ZDB5|B7ZDB5_DANRE Biglycan OS=Danio rerio OX=7955 GN=bgnb PE=1 SV=1 MSVMFSCRSLLLLLLSVCSLTAPSMALPFEQRGFWDFAMDGEAGDSTTVMMRDEEGSASE ELPPDVFICPFGCHCQVNIVQCSDLSLIAVPKEIPRDTKLLDLQNNCITELKENDFKGLT NLYALSLVNNKISKVHPRVFTPLRHLKKLYFSHNLLTVVPKNLPPSLVELRIHDNRIKKV AEGTFSGLGSMNCIEMGGNPIQNSGFEPGAFKGLKLNYLRVSEAKLTGIPKDLPDSLHEL HLDNNQIQAIELEDLRRYKHLYRLGLGFNQIRMIENGSLSYVSNLRELHLENNRLTRVPK GLPDMKYLQVAYLHSNNISQVDVNDFCPQGFGMKRNFYHGISLYGNPVNYWEVQPATFRC VADRLAIQFGNYKK >ADT80787.1 decorin [Cervus nippon] MKATIIFLLVAQVSWAGPFQQKGLFDFMLEDEASGIGPDDRFHEVPELEPMGPVCPFRCQCHLRVVQCSDLGLEAVPKDL PPDTALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHE NEITKVRKSVFNGLNQMIVVELGTNPRKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTELHLDGNKITKVDAA SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKLVKVPGGLADHKYIQVVYLHNNNISVIGSNDFCPPGYNT KKASYSGVSLFSNPVQYWEIQPSTFRCVYVRAAVQLGNYK
Selected proteins from model organisms >NP_001702.1 biglycan preproprotein [Homo sapiens] MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCH LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKL QKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKL NYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR ELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPA TFRCVTDRLAIQFGNYKK >CAE1318869.1 SLIT2 [Sepia pharaonis] MMLTMPGNERLAVIVALCGVISGVTGVATSAFLFTLTTALLCWLFHQRLHHERQLQTLNQNNDCGFPLWELESLFSTSVS HQARGSVSLFIAPFGRRRSGILMIWLHVLTACLLLGTSTVHARYNLGSRLHNGFSTGQNCPQRCACIGVSVDCSFRGLKT VPSDIPPETERLDLKGNNITHIRRTDFTGLRSIRVLQLPENRITKIERGAFQDLISMERL >XP_039261916.1 podocan-like [Styela clava] MVLLFNPLCTTLWKLMVLWIIFFTMPISSVGMTTKMMTKDSNNTSELHENCPVMCRCPTPETVDCSQAKLTDIPHDISQK AINLLLNGNRLSEISDECFSMCPRIQTLNLKGNEISEETISKNAFYALSNLHHLYLSQNKLQKIPKDLPNSIISLNLEGN FIHEVDDFALAQKQHLRRLYLHNNNITSESLSKKAFRRLLKLEEITLSNNFMQAIPLFPDYIERLHMENNQISGISSGIF RKKKKLIALYLQNNNLINEGLSSKSFTGLNRLEYLDLSNNELKEIPENIPKNIRRLHLEKNHLEKITHKSLAALQKLEYL LLQYNNLNSSSIDPGSFSKLRSLKTLHIFTNNLETVPSFLPPRLEYLILLSNGIKKLKRNTFAGARQIRDLNMRYNKITN SGLEKGAFRPLPRLTTIDLSGNQLTAVPSLPRSAEVVHLSDNRIVRIPHKSITRLSRLYHLVLSGNKLQTIANDIFKDSI KMKVYV >XP_006561501.1 protein slit isoform X1 [Apis mellifera] MARAMTPAWSLRLLGVSCGSVVCAWGLLLILSVLGGGASHGTALGSFGLGSLSGAMEDMNSARCPWLCTCTGQEVDCSHR GLTQIPGDLVTFLVAEKLDLQGNNISVIFKTDFEDMATLHVLWLSNNQIHTIERGAFQDLVGVEKLRLNNNQIRHLPDLL FSNMMNLKRLDLSHNQIATIGPKTLRGISSLKYLLLDNNVLTCIDEASIRELKDLEILMLNNNKLTTLGKEMLNGFSHLR TLKLVDNPLSCDCHLAWLSRHLKSYPRLGQHTKCASPIHLKDRNIADVQEHEFKCSGPVERTGSECSAEPQCPHPCRCAD GIVDCRENSLTKVPTHLPEDTTELRLEQNRITEIPPKAFSPYRKLRRIDLSNNQIKKVAADAFHGLKSLESLVLYGNKIT ELPSGLFQGLTNLQLLLLNANEISCIRTDLFRDLTSLTLLSLYDNNIRSLANGTFANLRSIETLHLARNPFICDCNLRWL NAYLHAHPIETSGAKCESPKRAQKRKIDSMRDDKFKCDEELLTKRAGECILPGECPDPCVCNGATVDCSNKKLTSIPKEL PIYTSTLLLANNELDKIKADGLFEKLPELQHLDLRKNKISRIEASSFQGAHKLTDLLLSENRLREVHNKMFTGLTNLKTL NLHGNAITCVMQGSFDGLTHIRTINMQGNPLSCNCHLAWFAGWLRKRETPLSGVVGHCHDPPRLKDAIVKDIPHHEFKCN NDSVGCLGDDYCPPQCNCAGSVVRCSRSQLTEIPRGIPPETTELYLDVNDIKTIQPERLNHLRILTRLDLSNNQIGMLSN DTFRNLTKLSHLIISYNKLQCVQRNALAGLKSLRIMSLHGNDISVIPEGAFEDLQSITHLALGSNPLYCDCSMRWLAEWV KKDYVEAGIARCMEPPAMRDKLLLTTPATAFQCKTSQQPAEVLAKCDLCYTSPCQNGGFCEALPDRKFRCKCAPGYHGDR CEHKIDACYGNPCGNTGTCKVLEEGRFSCDCAPGYKGLRCENNVDDCEDNKCSNNSTCVDLVQAYRCECAPGFMGEYCEE KIPFCTKGHDPCENGGRCVDHGTHYSCECPIGFTGLNCSTNLDDCVDHMCQNGATCIDGINNYECKCAADYTGRYCEAAP STVMLYPQTSPCAHHDCQHGACFQPAPASAADYLCQCHPGYTGKRCEYLTSLSFVDNSSLVELEPLRTRPEANVTIVFTT TQENGVLLYNGQNGDHIAVELFNGRVRVSYDVGNYPTSTMYSYEMVADGKAHVAELLAIKKNFTMRVDNGAARSIINEGP KEYLKLVAPMYVGGVAPEVANVAFTEFHLRNITSFQGCISEMWINHKLVDFSNAAKMHRVTPGCMSNEEEADEARDVVEA EGIMGSSNEESLPQEGMDHEHSDIVMTGPGTIISDPCTGHECRKGSQCVPSPIGNGYTCRCQTGWQGRYCEKAPTCRKEH TREYYSENGCRSRRPVKLAKCWGSCGNSCCLPRKTKRRKVRLICADGMRYTKDVDLVRKCTCTRKCY >XP_038070682.1 slit homolog 2 protein-like [Patiria miniata] MLISRKLFRGTGLLRSLNLENNQITCIIDGAFRPLRMLERLALSNNNLTTLSSSSFTHMTYLKTLRLAGNDLYCDCYLSW FASWLRLHPRLALSTRCSQPRQFRGLKVPELQVADFRCTGEEDHEVMCKVKPLCPAGCTCNSENVVDCRGIGLTELPRTF PDRAVELRLEQNQIRSIPSRAFTQYKKLKRIDLSNNMIETIADDAFVGLRALSSLVLYGNQINDLPEGIFRGLTSLQLLL LNANHISCIRVNLFQDLISLNLLSLYDNQIMSLANGTLAPLRNLQTMHLARNPLICDCNVKWLVEYLAENPVEKSGARCE NPRRMEGKRLNRMKSIKFKCKDAEYQRTMHAGDCFIDSDCPESCSCSGTIVDCSNRGFHSVPDNIPTYTTELLLNDNDIS RISAGGKFLNLINLSKLDLRNNRISIIEEGAFEGAANLFELLLTNNKLTKVRGRFFSGLKKLRTLNLRSNRLTCIGNETF IGLKSLRLLALYDNGISTITSGAFDSLKELSTVNLMGNPLNCNCHLSWLPEWLNSRNIVTGNPICQSPDNLRDVPLEDLA KTDFTCEENDLNSCLPSVACPRECACSGSVVRCSRKELTMPPRNIPLTATEIYLDSNQLVTIPEGMTNLKSLHTLDLSTN LITMLPENAFANMTKLSTLILSYNRIACIPPGTFTGLRSLRILSLQGNDLSTLPNGVFSDLHSLSHIALGNNPLYCDCHL QWLSEWVKADGFKEPGIAKCADPYDLRGKLILTAPSKSFVCTEEPDMNIQAKCDPCLSEPCENAGVCSVSLTERYTCDCP DGFKGRNCEVQLDACEDMPCLNGAQCRNLNGGFRCDCLAGFEGDLCGENIDDCKDHQCLNDAICQDGINNYTCYCSMGYS GTYCEVDKDLCAPGTNPCQNEGVCYDQGRSYRCDCQPGFRGVNCTETYQDCRSQACQHDGQCIQELEQWVCKCPPGFSGI NCQNPPVVFPQTSPCDFLNCQNNALCQEVNGEVSCQCRPGYVGERCEVSTSLTFSQQNALLSKSAPDMSHQINFTIAFAT TAENGILLYHGGAQGTMDHLAVELFRGYLRVSYDAGNFPATTMFGQQNLADEEFHTVQVLVAGRNISFQIDDEEMQSATN EGPSEYLVVDAPLYIGGAPSKRNQYALRHWHLRNGSSFHGCMRGFFINGVPVTPTDEVDVTGVTSGCPALDMPDPCQTNP CKQGFCRKLDSARYTCDCQDGWMGQMCDTKTTCTAQDRLFVPENENGSCRSATSIRTKVCSGECGISCCRPQRVRTRDII LQCDDGTEVKQEVKIVRSCACQECVDQSSPEILDGPE >XP_030837166.1 relaxin receptor 2-like [Strongylocentrotus purpuratus] MPPRVFIIGSGSCQWANDLIECDPGFFPCGNSTECVAQQFQCDDIAHCQNAADESGCAIADGWLAHFDYVHPVSVGETKA LNECALAQYPDGCVCSKLTQLDCSEFNLNEVPPNLPENITRLYLKSNNIVNIGSELLANYSSLVYLNLMGNRIHEIAENS FRNLRNLKRLFLSENNISRIQTGAFNGLSGLHWLFLNDNKMRTLEPGIFLGLEGLYWLDMRNNEIRDLQEGEALKDLKSL VWLDFEGNDIRSINARSFAGNTSLTVLILRNNSIESIERDAFTSLGTLVELDLSHNQISHLPEGIFDGLHTLEILRLRNN PLFSLPVDVFRGMKKLVDLDLAEIIIGNINVDMFQGLTRLEKVAFDKFEYCRYAPHVRTCTPRSDGISSFENLLKNVVLR VFVWTIGIITSVGNLGVLVSRAFMKAENKVHTVVVINLCTADFLMGIYLLIIGTHDVKYRDNYNQHALEWTNGITCKVSG LLAMISSEVSVLTLMFISLERYFIIVYPYSFQRIKTRRAIMVLAFIWFFGTLLAVVPIIPVDYFGNFYGSNGVCFPLHLH EPRMRGWEYSVVVFLGINSTAFVAIALSYTGMFLSIRKTRRAAAQCGMKGDMAYAKRFFFVILTDSLCWLPIAVLKVMSL CNFIISETLYGWIIVFVLPINSALNPILYTLSTTSFAMWFMRQLKRGKFKTSGCYIGSNVDMSELRGRIEESGAFTSYTN MPKRASFFLPTRKHHVSSKVEAIPAVSSSVPSRSATTTAMTNNIRPLHTINEGEIVDNNSQSQGNHQLRRTPIVRLCDLM E >ADT80787.1 decorin [Cervus nippon] MKATIIFLLVAQVSWAGPFQQKGLFDFMLEDEASGIGPDDRFHEVPELEPMGPVCPFRCQCHLRVVQCSDLGLEAVPKDL PPDTALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHE NEITKVRKSVFNGLNQMIVVELGTNPRKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTELHLDGNKITKVDAA SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKLVKVPGGLADHKYIQVVYLHNNNISVIGSNDFCPPGYNT KKASYSGVSLFSNPVQYWEIQPSTFRCVYVRAAVQLGNYK >KAB0341533.1 hypothetical protein FD754_018459 [Muntiacus muntjak] MWPLWPLAALLALSQALPFEQRAFWDFTLDDGLPMLNDEEASGAETTSGIPDLDSLPPTYSAMCPFGCHCHLRVVQCSDL GLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPS SLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHN KIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVND FCPVGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYKK >KAB0372067.1 hypothetical protein FD755_015859 [Muntiacus reevesi] MWPLWPLAALLALSQALPFEQKAFWDFTLDDGLPMLNDEEASGAETTSGIPDLDSLPPTYSAMCPFGCHCHLRVVQCSDL GLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPS SLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHN KIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPMLRELHLDNNKLSRVPSGLPDLKLLQVVYLHTNNITKVGVND FCPVGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYKK >NP_510426.1 Uncharacterized protein CELE_C44H4.3 [Caenorhabditis elegans] MLLRLCVALLVLPACLAFCPKLFQNQTACSCDSTVEGPVIKCSGHDGLRMVEKLSTTTTMEVRELALENADIIEVGPKAF KTLRIKKLILSNNRIEKIHDHAFTGLENVMQELSLSENNLKEVPTSALAGLRVLNILSLKCNKIENITTKAFVNMTSLID VNLGCNQICSMAADTFANVKMSLQNLILDNNCMTEFPSKAVRNMNNLIALHIKYNKINAIRQNDFVNLTSLSMLSLNGNN ISEIKGGALQNTPNLHYLYLNENNLQTLDNGVLEQFKQLQVLDLSFNNFTDITKEMFEGLESIQHLNLDSNRISAVAPGA FAGTPLLLLWLPNNCLTEVSQQTLKGAPFLRMVSLSNNNIREVHELSFDHLPNLHTLDLANNKIMSLQNKSLSGPENLAV RLQENPVVCVKNGFHVLNSGEAIWLTNEANTICKGEWQAQTADLCPKAQPRPIRPVCCSNEITTTTTTTTTTTTLAPTTT TEEEKEETTETTEKVTTVGKSKKTKATTTTEEPEDDEDVYVDDDEEGTEEEEEEVSTTEKSTTTTTTTTEASKSKKVNME RFWRLSNKPSGKSPFLRHSQGNKPRYLQTTTEAPEEEDEAEYISDDGGAEESEEAETTVATTTTTEPSVKVPARIRERQR MFASNIPWMAPRTKTDSVEEEFSKDDEVETVETAEKPARH >OWJ99220.1 BGN [Cervus elaphus hippelaphus] MRTAHTQNPSPLGMGIGWAPLMAPPHPGFAGTPTMWPLWPLAALLALSQALPFEQKAFWDFTLDDGLPMLNDEEASGAET TSGIPDLDSLPPTYSAMCPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNK ISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAF DGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLD NNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGN YKK >XP_041429161.1 biglycan [Xenopus laevis] MKVLLLLCSCILVIHALPFEQRGFWDFSMDDGMAMMKDEEASGVGPIPTESIPDVGLPPMDLCPFGCQCHLRVVQCSDLG LTSIPKNLPKDTTLLDLQNNKITEIKKDDFKGLTNLYALVIVNNKISKINEKAFEPLQKMQKLYISKNNLEEIPKNLPKS LVELRIHENKIKKVPKGVFSGLKNMNCIEMGGNPLENGGIEAGAFDGLKLNYLRVSEAKLSGIPKGLPSTLNELHLDNNK IQAIEKEDLSQYASLYRLGLGHNNIRMIENGSLSFMPVLRELHLDNNKLSKVPPGLPDMKLLQVVYLHSNNITQVGVNDF CPIGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYRK >XP_003210079.1 asporin [Meleagris gallopavo] MKEYTLLLFLALCSAKPLIGPSYFTLKNMMLQDMEEEDEDDDDDNSLFPTTEPIIPLIPFDLFPTCPFGCQCYVRVVHCS DLGLTSIPRNIPPDTRMIDLQNNKIREVKENDLQGLTTLYALALNNNKITKIHPKAFQPTKKLRRLYLSHNQLTEIPTNL PKTLAELRIHANKVKKIPKDAFKGMKSLHVLEMSANPLNNDGIEPGAFEGVNIYHIRIAEAKLTSIPKDLPSTLLELHLD DNKITAVELEDFNRYKDLQRLGLGNNKIKDVENGSFANIPSIREIHLEKNKLKKVPPGLPDLKYLQVVFLHSNHIAKLGV NDFCPTGRRKKKALYSGISLFNNPVKYWEVQPSTFRCILARNSVQLGNFLE >XP_043309693.1 asporin [Cervus canadensis] MKEYVLLVFLTLCSAKPLFHPSYMTLKNMMLKDMEDEGDSDADNSLFPTREPVNPFFPFDLFSTCPFGCQCYSRVVHCSD LGLSSVPSNIPFDTRLVDLQNNKIKEIKENDFKGLTSLYALILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLP KSLAELRIHDNKVKKIQKETFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSIPKDLPSTLLELHLDY NKISVVELEDFKRYKDLQRLGLGNNRITDIENGSLANIPRVREIHLENNKLKKVPSGLQELKYLQIIFLHSNSITKVGVN DFCPTVPKMKKSLYSAISLSNNPVKYWEVQPATFRCVLSRMSVQLGNFRK >XP_040537973.1 asporin [Gallus gallus] MKEYTLLLFLALCSAKPLIGPSYFTLKNMMLQDMEEEDEDDDDDNSLFPTTEPIISLIPFDLFPTCPFGCQCYVRVVHCS DLGLTSIPRNIPPDTRMIDLQNNKIREVKENDLQGLASLYALALNNNKITKIHPKAFQPTKNLRRLYLSHNQLTEIPTNL PKTLAELRIHANKVKKIPKDAFKGMKSLHVLEMSANPLNNDGIEPGAFEGVNIYHIRIAEAKLTSIPKDLPSSLLELHLD DNKITAVELEDFNRYKDLQRLGLGNNKIKDVENGSFANIPSIREIHLEKNKLKKVPPGLPDLRYLQVVFLHSNHIAKLGV NDFCPTGRRKKKALYSGISLFNNPVKYWEVQPSTFRCILARNSVQLGNFLK >XP_005508936.1 asporin [Columba livia] MKEYTLLLFLALCSAKPLIGPSYFTLKNMMVQDMEEEDDDDDDDNSLFPTTEPMIPLTPFDLFPTCPFGCQCYVRVVHCS DLGLTSIPRYIPPDTRMIDLQNNKIKEVKEKDLQGLTSLYALALNNNKITKIHPKAFQSTQKLRRLYLSHNQLTEIPTNL PKTLAELRIHANKVKKIHKDVFKGMKSLHVLEMSANPLDNDGIEPGAFEGVNIYHIRIAEAKLTSIPKDLPSSLLELHLD DNKITAIELEDFNRYKDLQRLGLGNNKIKDVENGSFANIPSIREIHLEKNKLKKVPPGLPELKYLQVVFLHSNHIAKLGV NDFCPTGRRKKKALYSGISLFNNPVKYWEVEPSTFRCILARNSVQLGNFLK >KAF4019508.1 hypothetical protein G4228_011300 [Cervus hanglu yarkandensis] MKEYVLLVFLTLCSAKPLFHPSYMTLKNMMLKDMEDEGDSDADNSLFPTREPVNPFFPFDLFSTCPFGCQCYSRVVHCSD LEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSIPKDLPSTLLELHLDYNKISVVELEDFKRYKDLQRLGLGNNRITD IENGSLANIPRVREIHLENNKLKKVPSGLQELKYLQIIFLHSNSITKVGVNDFCPTVPKMKKSLYSAISLSNNPVKYWEV QPATFRCVLSRMSVQLGNFRK >XP_004070537.1 biglycan [Oryzias latipes] MLLLRSSLLLLCLFQLHAPSSALPFEQRGFWDFSLDSMENIGKMAMMNDEEEGSAMEPTPSPGMPMCPFG CHCQRKVVQCSDLGLTEVPRNIPPDTRFLDLQNNQISELRENDFKGLTDLYALSVRNNIISKVHPRAFVP LKRMQKLYFSKNLLSTIPKNLPASLIELRIHENRIRKVGAGSFSGLTNMNCIEMGANPIQNSGFEPGAFK GLRLNFLRLSEAKLTGVPKDLPDSLHELHLDHNQIQAVELEDLSRYKNLYRLGLGFNNIRNIENGSLSYL PMLRELHLENNRLTRIPQGLPSMKYLQVVYLHSNSINHVDVDDFCPRGFGMKRTFYNGISLFDNPVNYWD VQPATFRCVNDRYAIQFGNYKK >XP_030278617.1 biglycan [Sparus aurata] MLPHCSVLLLLCVVRLLSPSSALPFEQRGFWDFAMDSMDSMDSMMTMMRDEEEGSAVEEILPPDIPMCPF GCHCQLRVVQCSDLGLTEVPKNIPRDTKFLDLQNNRITELKENDFAGLTNLYGLSLRNNHISKVHPRAFV PLKHMQKLYFSKNFLTTIPKNLPASLVEMRIHENRIKKVAAGAFSGLSNMNCIEMGANPIQNSGFEPGAF KGLKLNFLRISEAKLTGVPKDLPESLHELHLDHNEIQAVELEDLSRYKNLYRLGLGYNHIRNIENGSLSY LPRLRELHLENNRLTRVPRGLPDMKYLQVVYLHSNNIDQVGVDDFCPRGFGMKRAFYNGISLFANPVNYW EVQPATFRCVSDRLAIQFGNYKK >NP_031568.2 biglycan preproprotein [Mus musculus] MCPLWLLTLLLALSQALPFEQKGFWDFTLDDGLLMMNDEEASGSDTTSGVPDLDSVTPTFSAMCPFGCHC HLRVVQCSDLGLKTVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRK LQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTL RELHLDNNKLSRVPAGLPDLKLLQVVYLHSNNITKVGINDFCPMGFGVKRAYYNGISLFNNPVPYWEVQP ATFRCVTDRLAIQFGNYKK >NP_058783.1 biglycan precursor [Rattus norvegicus] MRPLWLLTLLLALSQALPFEQKGFWDFTLDDGLLMMNDEEASGSDTTSGVPDLDSLTPTFSAMCPFGCHC HLRVVQCSDLGLKTVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRK LQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTL RELHLDNNKLSRVPAGLPDLKLLQVVYLHSNNITKVGINDFCPMGFGVKRAYYNGISLFNNPVPYWEVQP ATFRCVTDRLAIQFGNYKK >NP_847888.2 biglycan precursor [Bos taurus] MWPLWPLAALLALSQALPFEQKAFWDFTLDDGLPMLNDEEASGAETTSGIPDLDSLPPTYSAMCPFGCHC HLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRK LQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTL RELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQP ATFRCVTDRLAIQFGNYKK >XP_013841982.2 biglycan isoform X1 [Sus scrofa] MWPLWLLASLLALSQALPFEQKAFWDFTLDDGLPMLNDEEASGADSTSGIPDLDALPPTFSAMCPFGCHC HLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHAKAFSPLRK LQKLYISKNHLVEIPPNLPSSLAELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRWARGPSGCHGTPAPRGLWAQPH QPVLLWPFSISHPPLHRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTN NITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYKK >XP_038304748.1 biglycan isoform X1 [Canis lupus familiaris] MPTMWPLWLVASLLALTQALPFEQKGFWDFTLDDGLPMLNDEEASGAETTSGVPDLDALTPTYSAMCPFG CHCHLRVVQCSDLGLKAVPKEISPDTMLLDLQNNDISELRADDFKGLHHLYALVLVNNKISKIHEKAFSP LRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFD GLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFL PTLRELHLDNNKLSRVPSGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWE VQPATFRCVTDRLAIQFGNYKK >NP_001009201.1 biglycan precursor [Ovis aries] MCPLWLLAALLALSQALPFEQKAFWDFTLDDGLPMLNDEEASGAETTSGIPDLDSLPPTYSAMCPFGCHC HLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRK LQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTL RELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQP ATFRCVTDRLAIQFGNYKK >XP_016799988.1 biglycan [Pan troglodytes] MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCH LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKL QKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKL NYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR ELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQPA TFRCVTDRLAIQFGNYKK >NP_001001825.2 biglycan b precursor [Danio rerio] MSVMFSCRSLLLLLLSVCSLTAPSMALPFEQRGFWDFAMDGEAGDSTTVMMRDEEGSASEELPPDVFICP FGCHCQVNIVQCSDLSLIAVPKEIPRDTKLLDLQNNCITELKENDFKGLTNLYALSLVNNKISKVHPRVF TPLRHLKKLYFSHNLLTVVPKNLPPSLVELRIHDNRIKKVAEGTFSGLGSMNCIEMGGNPIQNSGFEPGA FKGLKLNYLRVSEAKLTGIPKDLPDSLHELHLDNNQIQAIELEDLRRYKHLYRLGLGFNQIRMIENGSLS YVSNLRELHLENNRLTRVPKGLPDMKYLQVAYLHSNNISQVDVNDFCPQGFGMKRNFYHGISLYGNPVNY WEVQPATFRCVADRLAIQFGNYKK >tr|Q6GMI5|Q6GMI5_DANRE Biglycan OS=Danio rerio OX=7955 GN=bgna PE=2 SV=1 MLSVCVAFLFLCTAHLPIYSSALPFEQKGFWDFGKDIDVKELMMMMDQEEGSAVEPYKPE HPTCPFGCRCELRVVQCSDLGLGYVPYDIPADTLLLDLQSNRITEIREGDFKGLSNLYAL VLRYNQISKIHPKAFLPLKRLQKLYISHNLLTSMPKNLPSSLVELRIHDNRIKKVPAFSF SGLHNMHVIEMGRNPLQNSGFEPGAFMGLKLNYLRISEAKLTGVPKDLPGSLHELHLDNN QIQAIELVDLSQYTQLQRLGLGSNQIRHIEHGALSYLTNLRELHLDNNRLPSVPSGLSHM KYLQVVYLHSNNITNVGEDDFCPTGFGLKKVFYNGISLFDNPIRYWEVQPSTFRCVSDQM AVQFGNHKK >XP_008248493.1 PREDICTED: biglycan isoform X1 [Oryctolagus cuniculus] MFTGSLTTREAPGGPASGRAGTTSTMRPLWLLAALLALGQALPFEQKGFWDFALDDGLLMMNDEEASGAE STSGVPDLDALTPTFSSMCPFGCHCHLRVVQCSDLGLKTVPKEVSPDTTLLDLQNNDISELRKDDFKGLQ HLYALVLVNNKITKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRN MNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSK LYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHSNNITKVGVNDFCPVG FGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYKK >NP_001125588.1 biglycan precursor [Pongo abelii] MWSLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCH LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKL QKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKL NYLRISEAKLTGIPKDLPETLNELHLGHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR ELHLDNNKLAGVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQPA TFRCVTDRLAIQFGNYKK >XP_003804899.2 biglycan [Pan paniscus] MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCH LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHKKAFSPLRKL QKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKL NYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR ELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQPA TFRCVTDRLAIQFGNYKK >XP_004001049.2 biglycan [Felis catus] MPTMWPLWLLASLLALSQALPFEQKGFWDFTLDDGLPMLNDEEASGAETTSGVPDLDSLTPTFSAMCPFG CHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSP LRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFD GLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFL PTLRELHLDNNKLSRVPSGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWE VQPATFRCVTDRLAIQFGNYKK >XP_004065120.1 biglycan [Gorilla gorilla gorilla] MWPLWLLVSLLALSQALPFEQRGFWDFTLDDGPFLMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCH LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKL QKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKL NYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR ELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQPA TFRCVTDRLAIQFGNYKK >XP_017900688.1 PREDICTED: biglycan [Capra hircus] MWPLWPLAALLALSQALPFEQKAFWDFTLDDGLPMLNDEEASGAETTSGIPDLDSLPPTYSAMCPFGCHC HLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRK LQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTL RELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPFPYWEVQP ATFRCVTDRLAIQFGNYKK >XP_006032095.1 biglycan [Alligator sinensis] MVPLLLLALLYPTGALGLGLVPPFEQHGFLDFSLDDTPALGPGDEDEASGLFPTSGAPDLGLDELGLPPP SGHCPFGCHCHLRVVQCSDLGLKEVPKDLPPDTTLLDLQNNFISELRADAFKGLEHLYALVLVNNRLSRV DPKAWTPLRRLQKLYLSRNLLTRVPAPLPPALVELRIHDNKIRRVPKAVFHGLRQMNCIEMGGNPLENSG FEPGAFDGLQLNYLRISEAQLTGVPKDLPETLTELHLDHNQIQAIELEDLKRYSKLTRLGLGHNRVRGVE NGSLSFLPLLRDLHLEHNKLQRVPPGLPNLRHLQVVYLHANNISAVGPHDFCPPGFGVKRSPYHGISLFG NPLPAWEVPPAAFRCVSAPLAVQFGNYRK >XP_006269090.1 PREDICTED: biglycan [Alligator mississippiensis] MVPLLLLVLLCPTGALGLGLVPPFEQHGFLDFSLDDVPALGPGDEDEASGLFPTSGAPDLGLDELGLPPP SGHCPFGCHCHLRVVQCSDLGLKEVPKDLPPDTTLLDLQNNFISELRADAFKGLEHLYALVLVNNRLSRV DPKAWTPLRRLQKLYLSRNLLTRVPAPLPPALVELRIHDNKIRRVPKAVFHGLHQMNCIEMGGNPLENSG FEPGAFDGLQLNYLRISEAQLTGVPKDLPETLTELHLDHNQIQAIELEDLKRYSKLTRLGLGHNRVRGVE NGSLSFLPLLRELHLEHNKLQRVPPGLPNLRHLQVVYLHANNISAVGPHDFCPPGFGVKRSPYHGISLFG NPLPAWEVPPAAFRCVSAPLAVQFGNYRK >XP_015797476.1 PREDICTED: biglycan [Nothobranchius furzeri] MCPFGCHCQLRVVQCSDLGLTEVPKNIPSDTKFLDLQNNRITELKENDFRGLTNLYALSVRNNKISKVHP KTFAPLKRMQKLYFSKNLMSTIPKNLPASLVELRIHENRIKKVAAGAFSGLGNMNCIEMGANPIQNSGFE PGAFKGLRLNFLRISDAKLTGVPKDLPDSLHELHLDHNQIQAVELEDLSRYKNLYRLGLGFNHIRNIEQS SLLYLPRLRELHLDNNRLTHVPQDLPNMKYLQVVYLHSNNISQVGVDDFCPRGFGMKKAFYNGISLFENP VNYWEVQPATFRCVGDRFAIQFGNYKK >XP_020741083.1 biglycan [Odocoileus virginianus texanus] MWPLWPLAALLALSQALPFEQKAFWDFTLDDGLPMLNDEEASGAETTSGIPDLDSLPPTYSAMCPFGCHC HLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRK LQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTL RELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPYWEVQP ATFRCVTDRLAIQFGNYKK >XP_040178826.1 biglycan [Rana temporaria] MKVLLLICTSVLLCNALPFEQRGFWDFSMDDGLTMMRDEANEEGSGFSTATPGKKGPTAFPPHMPPMDLC PFGCQCHLRVVQCSDLGLTSVPKNIPKDTMLLDLQNNKIMEIKKDDLKGLSKLYALVLVNNKISKVNEKA FEPCSNLQKLYISKNSLEEIPKSLPKSLVELRIHENKIKKIPKDVFNGLKNMNCIELGGNPLENGGIDAG AFNGLKLNYLRISEAKLSGIPKGLPASLNELHLDHNRIQAVEMGDLSTLPNLYRLGLGYNIIRQVENGSL SSLPILRELHLDNNKLAKVPPGLPDLKFLQVVYLHSNNITQVGVNDFCPTGFGVKRAYYNGISLFNNPVP YWEVQPATFRCVTDRLAIQFGNYRK
Mafft alignment of selected proteins >NP_001702.1 biglycan preproprotein [Homo sapiens] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MWP-------------- --------------------------------------LWRLVSLLALSQAL-------- -----------------------------------------PFEQRGFWDFTLD-----D G-PFMMND-----EEASGAD-T-SGVLD---PDSVTP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLARVPSG-LPDLKLLQVV YLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >CAE1318869.1 SLIT2 [Sepia pharaonis] M----------------------------------------------------------- ------------------------------------------------------------ -------------------------------------------MLT-------------- ----MPGNERLAVIV----ALCGVISGVTGVATSAFLFTLTTALLCWLFHQRLHHERQLQ TLNQ-----NNDCGFPLWELESLFSTSVSHQARGSVSLFIAPFGRRRSGILMIWLHVLTA CLLLGTSTVHARYNLGSRLHNG------------------FSTGQNC------PQRCACI G----VSVDCSFRG----LKTVPSDIPPETERLDLKGNNITHIRRTDFTGLRSIRVLQLP ENRITK--IERGAFQDLIS-MERL------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_039261916.1 podocan-like [Styela clava] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MVLLFNPLCTTLWKLM-------- --------------V-LWIIFFTM-----------------PISSVGMTTKMMT----KD S------------NNTSELHEN------------------------C------PVMCRCP TP---ETVDCSQAK----LTDIPHDISQKAINLLLNGNRLSEISDECFSMCPRIQTLNLK GNEISEETISKNAFYALSN-LHHLYLSQNKLQKIPKDLPNSIISLNL---EGNFIHEVDD FALAQKQHLRRLYLHNNNITS--------------------------------------- --------ESLSKKAFRRLLKLEEITL--------------------------------- --SNNFMQAIP-LFPDYIERLHMENNQISG------------------------------ ------------------------------------------------------------ -------ISSGIFRKKKKLIALYLQNNNLINE-----------------------GLSSK SFTGLN-------------------------------RLEYLDLSNNELKEIPENIP--- -KNIRRLHLEKNHLEKITHKSLAALQKLE------------------------------- --------YLLLQYNNLNSSSIDPGSFSKLRSLKTLHIFTNNLETVPSF-LP--PRLEYL ILLSNGIKKLKRNTF------AGARQIRDLNMRYNKIT----------------NSG--- ---------------LEKGA---------------------------------------- -------------------------------------FRP-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------LPRLTTIDL----------------------SG NQLTAV--------PSLPRSAEVVHLSDNRIVRI------------PHKSITRLSRLY-- ---------------HL-----------------------------------VLSG---- ------------------------------------------------------------ -----------------------------------------------------NKLQTIA ND-----------------------------------------------IFKDSIK---M KVYV---------------------- >XP_006561501.1 protein slit isoform X1 [Apis mellifera] MARAMTPAWSLRLLGVSCGSVVCAWGLLLILSVLGGGASHGTALGSFGLGSLSGAMEDMN SARCPWLCTCTGQEVDCSHRGLTQIPGDLVTFLVAEKLDLQGNNISVIFKTDFEDMATLH VLWLSNNQIHTIERGAFQDLVGVEKLRLNNNQIRHLPDLLFSNMMNLKRLDLSHNQIATI GPKTLRGISSLKYLLLDNNVLTCIDEASIRELKDLEILMLNNNKLTTLGKEMLNGFSHLR TLKLVDNPLSCDCHL-AWLSRHLKS----YPRLGQHTKCASPIHLKDRNIADVQ---EHE F------------KCSGPVERT----G-----------SECSAEPQC------PHPCRCA D----GIVDCRENS----LTKVPTHLPEDTTELRLEQNRITEIPPKAFSPYRKLRRIDLS NNQIKK--VAADAFHGLKS-LESLVLYGNKITELPSGLFQGLTNLQLLLLNANEISCIRT DLFRDLTSLTLLSLYDNNIRSLANGTFANLRSIETLHLARNPFICDCNLRWLNAYLHAHP IETSGAKCESPKRAQKRKIDSMRDDKFKCD--EELLTKRAGECILPGECPDPCVCNGATV DCSNKKLTSIPKELPIYTSTLLLANNELDKIKADGLFEKLPELQHLDLRKNKISRIEASS FQGAHKLTDLLLSENRLREVHNKMFTGLTNLKTLNLHGNAITC----------------- -------VMQGSFDGLTHIRTINMQGNPLSCNCHLAWFAGWLRKRETPLSGVVGHCHDPP RLKDAIVKDIPHHEFKC-NNDSVGCLGDDYCPPQCNCAGSVVRCSRSQLTEIPRGIP--- -PETTELYLDVNDIKTIQPERLNHLRILT------------------------------- --------RLDLSNNQIG--MLSNDTFRNLTKLSHLIISYNKLQCVQRNALAGLKSLRIM SLHGNDISVIPEGAF------EDLQSITHLALGSNPLYCDCSMRWLAEWVKKD-YVEAGI ARCMEPPAMRDKLLLTTPATAFQCKTSQQPAEVLAKCDLCYTSPCQNGGFCEALPDRKFR CKCAPGYHGDRCEHKIDACYGNPCGNTGTCKVLEEGRFSCDCAPGYKGLRCENNVDDCED NKCSNNSTCVDLVQAYRCECAPGFMGEYCEEKIPFCTKGHDPCENGGRCVDHGTHYSCEC PIGFTGLNCSTNLDDCVDHMCQNGATCIDGINNYECKCAADY-TGRYCEAAPSTVMLYPQ TSPCAHHDCQHGACFQPAPASAADYLCQCHPGYTGKRCEYLTSLSFVDNSSLVELEPLRT RPEANVTIVFTTTQENGVLLYNG---QNGDHIAVELFNG------------RVRVSYDVG NYPTSTMYSYEMVADGKAHVAELLAIKKNFTMRVDNGAARSIINEGPKEYLKLVAPMYVG G-VAPEVANVAFTEFHLRNITSFQGCISEMWINHKLVDFSNA-----AKMHRVTPGCMSN EEEADEARDVVEAEGIMGSSNEESLPQEGMDHEHSDIVMTGPGTIISDPC--TGHECRKG SQCVPSPIGNGY-TCRCQTG-------WQGRYCEKA-----PTCRKE-----HTREYYSE N---GCRS-RRPVKLAKCWGSCGNSCCLPRKTKRRKVRL----------ICADGMRY-TK DVDLVRKCTCTRKCY----------- >XP_038070682.1 slit homolog 2 protein-like [Patiria miniata] M----------------------------------------------------------- ------------------------------------------------------------ -------------------------------------------LIS-------------- -RKLFRGTGLLRSLNLENNQITCIIDGAFRPLRMLERLALSNNNLTTLSSSSFTHMTYLK TLRLAGNDLYCDCYL-SWFASWLRL----HPRLALSTRCSQPRQFRGLKVPELQ---VAD F------------RCTGEEDHE----------------VMCKVKPLC------PAGCTCN SE---NVVDCRGIG----LTELPRTFPDRAVELRLEQNQIRSIPSRAFTQYKKLKRIDLS NNMIET--IADDAFVGLRA-LSSLVLYGNQINDLPEGIFRGLTSLQLLLLNANHISCIRV NLFQDLISLNLLSLYDNQIMSLANGTLAPLRNLQTMHLARNPLICDCNVKWLVEYLAENP VEKSGARCENPRRMEGKRLNRMKSIKFKCKDAEYQRTMHAGDCFIDSDCPESCSCSGTIV DCSNRGFHSVPDNIPTYTTELLLNDNDISRISAGGKFLNLINLSKLDLRNNRISIIEEGA FEGAANLFELLLTNNKLTKVRGRFFSGLKKLRTLNLRSNRLTCIGNETFIGLKSLRLLAL YDNGISTITSGAFDSLKELSTVNLMGNPLNCNCHLSWLPEWLNSRNIVTGNPI--CQSPD NLRDVPLEDLAKTDFTCEENDLNSCLPSVACPRECACSGSVVRCSRKELTMPPRNIP--- -LTATEIYLDSNQLVTI-PEGMTNLKSLH------------------------------- --------TLDLSTNLIT--MLPENAFANMTKLSTLILSYNRIACIPPGTFTGLRSLRIL SLQGNDLSTLPNGVF------SDLHSLSHIALGNNPLYCDCHLQWLSEWVKADGFKEPGI AKCADPYDLRGKLILTAPSKSFVC-TEEPDMNIQAKCDPCLSEPCENAGVCSVSLTERYT CDCPDGFKGRNCEVQLDACEDMPCLNGAQCRNLNGG-FRCDCLAGFEGDLCGENIDDCKD HQCLNDAICQDGINNYTCYCSMGYSGTYCEVDKDLCAPGTNPCQNEGVCYDQGRSYRCDC QPGFRGVNCTETYQDCRSQACQHDGQCIQELEQWVCKCPPGF-SGINCQNPP---VVFPQ TSPCDFLNCQNNALCQEVNGEVS---CQCRPGYVGERCEVSTSLTFSQQNALLSKSAPDM SHQINFTIAFATTAENGILLYHGGAQGTMDHLAVELFRG------------YLRVSYDAG NFPATTMFGQQNLADEEFHTVQVLVAGRNISFQIDDEEMQSATNEGPSEYLVVDAPLYIG G-APSKRNQYALRHWHLRNGSSFHGCMRGFFINGVPVTPTDE-----VDVTGVTSGC--- -----------------------------------------PALDMPDPC--QTNPCKQG --FCRKLDSARY-TCDCQDG-------WMGQMCDTK-----TTCTAQ------DRLFVPE NENGSCRS-ATSIRTKVCSGECGISCCRPQRVRTRDIIL----------QCDDGTEV-KQ EVKIVRSCACQECVDQSSPEILDGPE >XP_030837166.1 relaxin receptor 2-like [Strongylocentrotus purpuratus] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MPP-------------- -----------------------------------RVFIIGSGSCQWANDLI-------- ---------ECDPGF-F------------------------PCGNSTECVAQQF---QCD DIAHCQNAAD---ESGCAIADGWLAHFD---YVHPVSVGETKALNEC-ALAQYPDGCVCS KL---TQLDCSEFN----LNEVPPNLPENITRLYLKSNNIVNIGSELLANYSSLVYLNLM GNRIHE--IAENSFRNLRN-LKRLFLSENNISR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------IQTGAFNGLSGLHWLFLNDNKMR-------------------------TLEPG IFLGLE-------------------------------GLYWLDMRNNEIRDLQEGEALKD LKSLVWLDFEGNDIRSINARSFAGNTSLT------------------------------- --------VLILRNNSIE--SIERDAFTSLGTLVELDLSHNQISHLPEGIFDGLHTLEIL RLRNNPLFSLPVDVF------RGMKKLVDLDLAEIIIG----------NINVDMFQG--- ------------LTRLEKVA-FD------------------------------------- --------------KFEYCRYAPHVRTCT--------PRSDGISSFEN------------ --LLKNVVLRVFVWTIGIITSVGNLGVLVSRAF--------------------------- ------------------MKAENKVHTVVVIN----LCTADFLMGIY--------LLIIG THDVKYRDNYNQHALEWTN---------------GITCKVSGLLAMISSEVSV------- -----LTLMFISLERYFIIVYPYSFQRIKTRRAIMVLAFIWFFGTLLAVVPIIPVDY-FG NFYGSN----GVCFPLHLHEPRMRGWEYSVVVFL----------GINSTAFVAIALSYTG MFLSIRKTRRAAAQCGMKGDMAY---AKRFFF----VILTDSLCWLPIAVLKVMSLC--- --------NFIISETLYGWI----------------IVFVLPINSALNPILYTLSTTSFA MWFMRQLKRGKFKTSGCYIGSNVDMSELRGRIEESGAFTSYTNMPKRASFFLPTRKHHVS SKVEAIPAVSSSVPSRSATTTAMTNNIRPLHTINEGEIVDNN-------SQSQGNHQ-LR RTPIVRLCDLME-------------- >ADT80787.1 decorin [Cervus nippon] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MKA-------------- -----------------------------------TIIFLL---VAQVSWAG-------- -----------------------------------------PFQQKGLFDFMLE------ -------------DEASGIGPD-----D---RFHEVPEL-EPMGPVC------PFRCQCH L----RVVQCSDLG----LEAVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLHTLILI NNKISK--ISPGAFAPLVK-LERLYLSKNQLKELPEKMPKTLQELRV------------- --------------HENEITK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VRKSVFNGLNQMIVVELGTNPRKSS-----------------------GIENG AFQGMK-------------------------------KLSYIRIADTNITTIPQGLP--- -PSLTELHLDGNKITKVDAASLKGLNNLA------------------------------- --------KLGLSFNSIS--AVDNGSLANTPHLRELHLNNNKLVKVPGG-LADHKYIQVV YLHNNNISVIGSNDFCPPGYNTKKASYSGVSLFSNPVQ----------------YWE--- ---------------IQPST---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VYVRAAVQ-----------------------LG NYK--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >KAB0341533.1 hypothetical protein FD754_018459 [Muntiacus muntjak] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MWP-------------- --------------------------------------LWPLAALLALSQAL-------- -----------------------------------------PFEQRAFWDFTLD-----D G-LPMLND-----EEASGAETT-SGIPD---LDSLPP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLSRVPAG-LPDLKLLQVV YLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >KAB0372067.1 hypothetical protein FD755_015859 [Muntiacus reevesi] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MWP-------------- --------------------------------------LWPLAALLALSQAL-------- -----------------------------------------PFEQKAFWDFTLD-----D G-LPMLND-----EEASGAETT-SGIPD---LDSLPP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPMLRELHLDNNKLSRVPSG-LPDLKLLQVV YLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >NP_510426.1 Uncharacterized protein CELE_C44H4.3 [Caenorhabditis elegans] M----------------------------------------------------------- ------------------------------------------------------------ -------------------------------------------LLR-------------- ---------------------LCV-----------ALLVL-------------------- -----------------------------------------P------------------ -----------------------------------------ACLAFCPKLFQNQTACSCD STVEGPVIKCSGHDGLRMVEKLSTTTTMEVRELALENADIIEVGPKAFKTL-RIKKLILS NNRIEK--IHDHAFTGLENVMQELSLSENNLKEVPTSALAGLRVLNI------------- -----------LSLKCNKIEN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------ITTKAFVNMTSLIDVNLGCNQICSM-----------------------AADTF ANVKM--------------------------------SLQNLILDNNCMTEFPSKAVR-N MNNLIALHIKYNKINAIRQNDFVNLTSLS------------------------------- --------MLSLNGNNIS--EIKGGALQNTPNLHYLYLNENNLQTLDNGVLEQFKQLQVL DLSFNNFTDITKEMF------EGLESIQHLNLDSNRIS---------------------- --------------AVAPGA-----FAGTPLLLLWLPNNCLTEVSQQ------------- -----------------TLKGAPFLRMVSLSNNN---IREVHELSFDHLPNLHTLD---- --LANNKIMSLQNKSLS---GPENLAVRLQ-------------ENPVVCVKNGFH----- --------------------VLNSGEAIWLTNEANTICKGEW-QAQTADLCPK-----AQ PRPIRPVCCSN---------------------------EITTTTTTTTTTT--------- ------TLAPTTTTEE--------EKEETTETTEKVTT--------------------VG KSKKTK-------ATTTTEEPE-----DDEDVYVDDDE------EGTEEEEEEVSTTEKS T-TTTTTTTEASKSKKVN--------MERFW-----------------RLSNKPSGK--- ----------------------------------------SP------------------ --FLRHSQGNKP------------------RYLQTT-----TEAPEE-----EDEAEYIS DDGGAEES-EEAETTVATTTTTEPSVKVPARIRERQRMFASNIPWMAPRTKTDSVEEEFS KDDEVETVETAEKPARH--------- >OWJ99220.1 BGN [Cervus elaphus hippelaphus] MR---TAH-TQNPSPLGMG---IGW------APLMAPPHPGFA-G--------------- ------------------------------------------------------------ ----------------------------------------TPTMWP-------------- --------------------------------------LWPLAALLALSQAL-------- -----------------------------------------PFEQKAFWDFTLD-----D G-LPMLND-----EEASGAETT-SGIPD---LDSLPP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLSRVPAG-LPDLKLLQVV YLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_041429161.1 biglycan [Xenopus laevis] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MKV-------------- --------------------------------------LLLLCSCILVIHAL-------- -----------------------------------------PFEQRGFWDFSMD-----D G-MAMMKD-----EEASGVGPI---------PTESIPDVGLPPMDLC------PFGCQCH L----RVVQCSDLG----LTSIPKNLPKDTTLLDLQNNKITEIKKDDFKGLTNLYALVIV NNKISK--INEKAFEPLQK-MQKLYISKNNLEEIPKNLPKSLVELRI------------- --------------HENKIKK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLKNMNCIEMGGNPLENG-----------------------GIEAG AFDGL--------------------------------KLNYLRVSEAKLSGIPKGLP--- -STLNELHLDNNKIQAIEKEDLSQYASLY------------------------------- --------RLGLGHNNIR--MIENGSLSFMPVLRELHLDNNKLSKVPPG-LPDMKLLQVV YLHSNNITQVGVNDFCPIGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYRK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_003210079.1 asporin [Meleagris gallopavo] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MKE-------------- -----------------------------------YTLLL----FLALCSAK-------- -----------------------------------------PLIGPSY--FTLK-----N MMLQDMEEEDEDDDDDNSLFPT---------TEPIIPLIPFDLFPTC------PFGCQCY V----RVVHCSDLG----LTSIPRNIPPDTRMIDLQNNKIREVKENDLQGLTTLYALALN NNKITK--IHPKAFQPTKK-LRRLYLSHNQLTEIPTNLPKTLAELRI------------- --------------HANKVKK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------IPKDAFKGMKSLHVLEMSANPLNND-----------------------GIEPG AFEGV--------------------------------NIYHIRIAEAKLTSIPKDLP--- -STLLELHLDDNKITAVELEDFNRYKDLQ------------------------------- --------RLGLGNNKIK--DVENGSFANIPSIREIHLEKNKLKKVPPG-LPDLKYLQVV FLHSNHIAKLGVNDFCPTGRRKKKALYSGISLFNNPVK----------------YWE--- ---------------VQPST---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ILARNSVQ-----------------------LG NFLE-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_043309693.1 asporin [Cervus canadensis] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MKE-------------- -----------------------------------YVLLV----FLTLCSAK-------- -----------------------------------------PLFHPSY--MTLK-----N MMLKDMEDEG-DSDADNSLFPT---------REPVNPFFPFDLFSTC------PFGCQCY S----RVVHCSDLG----LSSVPSNIPFDTRLVDLQNNKIKEIKENDFKGLTSLYALILN NNKLTK--IHPKAFLTTKK-LRRLYLSHNQLSEIPLNLPKSLAELRI------------- --------------HDNKVKK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------IQKETFKGMNALHVLEMSANPLDNN-----------------------GIEPG AFEGV--------------------------------TVFHIRIAEAKLTSIPKDLP--- -STLLELHLDYNKISVVELEDFKRYKDLQ------------------------------- --------RLGLGNNRIT--DIENGSLANIPRVREIHLENNKLKKVPSG-LQELKYLQII FLHSNSITKVGVNDFCPTVPKMKKSLYSAISLSNNPVK----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VLSRMSVQ-----------------------LG NFRK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_040537973.1 asporin [Gallus gallus] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MKE-------------- -----------------------------------YTLLL----FLALCSAK-------- -----------------------------------------PLIGPSY--FTLK-----N MMLQDMEEEDEDDDDDNSLFPT---------TEPIISLIPFDLFPTC------PFGCQCY V----RVVHCSDLG----LTSIPRNIPPDTRMIDLQNNKIREVKENDLQGLASLYALALN NNKITK--IHPKAFQPTKN-LRRLYLSHNQLTEIPTNLPKTLAELRI------------- --------------HANKVKK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------IPKDAFKGMKSLHVLEMSANPLNND-----------------------GIEPG AFEGV--------------------------------NIYHIRIAEAKLTSIPKDLP--- -SSLLELHLDDNKITAVELEDFNRYKDLQ------------------------------- --------RLGLGNNKIK--DVENGSFANIPSIREIHLEKNKLKKVPPG-LPDLRYLQVV FLHSNHIAKLGVNDFCPTGRRKKKALYSGISLFNNPVK----------------YWE--- ---------------VQPST---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ILARNSVQ-----------------------LG NFLK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_005508936.1 asporin [Columba livia] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MKE-------------- -----------------------------------YTLLL----FLALCSAK-------- -----------------------------------------PLIGPSY--FTLK-----N MMVQDMEEEDDDDDDDNSLFPT---------TEPMIPLTPFDLFPTC------PFGCQCY V----RVVHCSDLG----LTSIPRYIPPDTRMIDLQNNKIKEVKEKDLQGLTSLYALALN NNKITK--IHPKAFQSTQK-LRRLYLSHNQLTEIPTNLPKTLAELRI------------- --------------HANKVKK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------IHKDVFKGMKSLHVLEMSANPLDND-----------------------GIEPG AFEGV--------------------------------NIYHIRIAEAKLTSIPKDLP--- -SSLLELHLDDNKITAIELEDFNRYKDLQ------------------------------- --------RLGLGNNKIK--DVENGSFANIPSIREIHLEKNKLKKVPPG-LPELKYLQVV FLHSNHIAKLGVNDFCPTGRRKKKALYSGISLFNNPVK----------------YWE--- ---------------VEPST---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ILARNSVQ-----------------------LG NFLK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >KAF4019508.1 hypothetical protein G4228_011300 [Cervus hanglu yarkandensis] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MKE-------------- -----------------------------------YVLLV----FLTLCSAK-------- -----------------------------------------PLFHPSY--MTLK-----N MMLKDMEDEG-DSDADNSLFPT---------REPVNPFFPFDLFSTC------PFGCQCY S----RVVHCSD------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LEMSANPLDNN-----------------------GIEPG AFEGV--------------------------------TVFHIRIAEAKLTSIPKDLP--- -STLLELHLDYNKISVVELEDFKRYKDLQ------------------------------- --------RLGLGNNRIT--DIENGSLANIPRVREIHLENNKLKKVPSG-LQELKYLQII FLHSNSITKVGVNDFCPTVPKMKKSLYSAISLSNNPVK----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VLSRMSVQ-----------------------LG NFRK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_004070537.1 biglycan [Oryzias latipes] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MLL-------------- ---------------------LRS-----------SLLLLCLFQLHAPSSAL-------- -----------------------------------------PFEQRGFWDFSLDSMENIG K-MAMMNDE----EEGSAMEPT-------------PS----PGMPMC------PFGCHCQ R----KVVQCSDLG----LTEVPRNIPPDTRFLDLQNNQISELRENDFKGLTDLYALSVR NNIISK--VHPRAFVPLKR-MQKLYFSKNLLSTIPKNLPASLIELRI------------- --------------HENRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VGAGSFSGLTNMNCIEMGANPIQNS-----------------------GFEPG AFKGL--------------------------------RLNFLRLSEAKLTGVPKDLP--- -DSLHELHLDHNQIQAVELEDLSRYKNLY------------------------------- --------RLGLGFNNIR--NIENGSLSYLPMLRELHLENNRLTRIPQG-LPSMKYLQVV YLHSNSINHVDVDDFCPRGFGMKRTFYNGISLFDNPVN----------------YWD--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VNDRYAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_030278617.1 biglycan [Sparus aurata] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MLP-------------- ---------------------HCS-----------VLLLLCVVRLLSPSSAL-------- -----------------------------------------PFEQRGFWDFAMDSMDSMD SMMTMMRDE----EEGSAVEEI-------------LP----PDIPMC------PFGCHCQ L----RVVQCSDLG----LTEVPKNIPRDTKFLDLQNNRITELKENDFAGLTNLYGLSLR NNHISK--VHPRAFVPLKH-MQKLYFSKNFLTTIPKNLPASLVEMRI------------- --------------HENRIKK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VAAGAFSGLSNMNCIEMGANPIQNS-----------------------GFEPG AFKGL--------------------------------KLNFLRISEAKLTGVPKDLP--- -ESLHELHLDHNEIQAVELEDLSRYKNLY------------------------------- --------RLGLGYNHIR--NIENGSLSYLPRLRELHLENNRLTRVPRG-LPDMKYLQVV YLHSNNIDQVGVDDFCPRGFGMKRAFYNGISLFANPVN----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VSDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >NP_031568.2 biglycan preproprotein [Mus musculus] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MCP-------------- --------------------------------------LWLLTLLLALSQAL-------- -----------------------------------------PFEQKGFWDFTLD-----D G-LLMMND-----EEASGSDTT-SGVPD---LDSVTP----TFSAMC------PFGCHCH L----RVVQCSDLG----LKTVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLSRVPAG-LPDLKLLQVV YLHSNNITKVGINDFCPMGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >NP_058783.1 biglycan precursor [Rattus norvegicus] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MRP-------------- --------------------------------------LWLLTLLLALSQAL-------- -----------------------------------------PFEQKGFWDFTLD-----D G-LLMMND-----EEASGSDTT-SGVPD---LDSLTP----TFSAMC------PFGCHCH L----RVVQCSDLG----LKTVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLSRVPAG-LPDLKLLQVV YLHSNNITKVGINDFCPMGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >NP_847888.2 biglycan precursor [Bos taurus] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MWP-------------- --------------------------------------LWPLAALLALSQAL-------- -----------------------------------------PFEQKAFWDFTLD-----D G-LPMLND-----EEASGAETT-SGIPD---LDSLPP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLSRVPAG-LPDLKLLQVV YLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_013841982.2 biglycan isoform X1 [Sus scrofa] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MWP-------------- --------------------------------------LWLLASLLALSQAL-------- -----------------------------------------PFEQKAFWDFTLD-----D G-LPMLND-----EEASGADST-SGIPD---LDALPP----TFSAMC------PFGCHCH L----RVVQCSDLG----LKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHAKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLAELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLYRWARGPSGCHGTPAPRGLWAQPHQPVLLWPF SISHPPLHRLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLSRVPAG-LPDLKLLQVV YLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_038304748.1 biglycan isoform X1 [Canis lupus familiaris] M----------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------PTMWP-------------- --------------------------------------LWLVASLLALTQAL-------- -----------------------------------------PFEQKGFWDFTLD-----D G-LPMLND-----EEASGAETT-SGVPD---LDALTP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKAVPKEISPDTMLLDLQNNDISELRADDFKGLHHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLSRVPSG-LPDLKLLQVV YLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >NP_001009201.1 biglycan precursor [Ovis aries] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MCP-------------- --------------------------------------LWLLAALLALSQAL-------- -----------------------------------------PFEQKAFWDFTLD-----D G-LPMLND-----EEASGAETT-SGIPD---LDSLPP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLSRVPAG-LPDLKLLQVV YLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_016799988.1 biglycan [Pan troglodytes] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MWP-------------- --------------------------------------LWRLVSLLALSQAL-------- -----------------------------------------PFEQRGFWDFTLD-----D G-PFMMND-----EEASGAD-T-SGVLD---PDSVTP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLARVPSG-LPDLKLLQVV YLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >NP_001001825.2 biglycan b precursor [Danio rerio] M----------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------SVMFS-------------- ---------------------CRS----------LLLLLLSVCSLTAPSMAL-------- -----------------------------------------PFEQRGFWDFAMDG-EAGD STTVMMRD-----EEGSASEEL--------------P----PDVFIC------PFGCHCQ V----NIVQCSDLS----LIAVPKEIPRDTKLLDLQNNCITELKENDFKGLTNLYALSLV NNKISK--VHPRVFTPLRH-LKKLYFSHNLLTVVPKNLPPSLVELRI------------- --------------HDNRIKK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VAEGTFSGLGSMNCIEMGGNPIQNS-----------------------GFEPG AFKGL--------------------------------KLNYLRVSEAKLTGIPKDLP--- -DSLHELHLDNNQIQAIELEDLRRYKHLY------------------------------- --------RLGLGFNQIR--MIENGSLSYVSNLRELHLENNRLTRVPKG-LPDMKYLQVA YLHSNNISQVDVNDFCPQGFGMKRNFYHGISLYGNPVN----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VADRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >tr|Q6GMI5|Q6GMI5_DANRE Biglycan OS=Danio rerio OX=7955 GN=bgna PE=2 SV=1 ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MLS-------------- ---------------------VCV-----------AFLFLCTAHLPIYSSAL-------- -----------------------------------------PFEQKGFWDFGKDI-DVKE L-MMMMDQ-----EEGSAVEPY------------------KPEHPTC------PFGCRCE L----RVVQCSDLG----LGYVPYDIPADTLLLDLQSNRITEIREGDFKGLSNLYALVLR YNQISK--IHPKAFLPLKR-LQKLYISHNLLTSMPKNLPSSLVELRI------------- --------------HDNRIKK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPAFSFSGLHNMHVIEMGRNPLQNS-----------------------GFEPG AFMGL--------------------------------KLNYLRISEAKLTGVPKDLP--- -GSLHELHLDNNQIQAIELVDLSQYTQLQ------------------------------- --------RLGLGSNQIR--HIEHGALSYLTNLRELHLDNNRLPSVPSG-LSHMKYLQVV YLHSNNITNVGEDDFCPTGFGLKKVFYNGISLFDNPIR----------------YWE--- ---------------VQPST---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VSDQMAVQ-----------------------FG NHKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_008248493.1 PREDICTED: biglycan isoform X1 [Oryctolagus cuniculus] MF---TGSLTTREAP--------------------GGPASGRA-GT-------------- ------------------------------------------------------------ ----------------------------------------TSTMRP-------------- --------------------------------------LWLLAALLALGQAL-------- -----------------------------------------PFEQKGFWDFALD-----D G-LLMMND-----EEASGAEST-SGVPD---LDALTP----TFSSMC------PFGCHCH L----RVVQCSDLG----LKTVPKEVSPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKITK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLSRVPAG-LPDLKLLQVV YLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >NP_001125588.1 biglycan precursor [Pongo abelii] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MWS-------------- --------------------------------------LWRLVSLLALSQAL-------- -----------------------------------------PFEQRGFWDFTLD-----D G-PFMMND-----EEASGAD-T-SGVLD---PDSVTP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLGHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLAGVPSG-LPDLKLLQVV YLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_003804899.2 biglycan [Pan paniscus] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MWP-------------- --------------------------------------LWRLVSLLALSQAL-------- -----------------------------------------PFEQRGFWDFTLD-----D G-PFMMND-----EEASGAD-T-SGVLD---PDSVTP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHKKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLARVPSG-LPDLKLLQVV YLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_004001049.2 biglycan [Felis catus] M----------------------------------------------------------- ------------------------------------------------------------ -----------------------------------------PTMWP-------------- --------------------------------------LWLLASLLALSQAL-------- -----------------------------------------PFEQKGFWDFTLD-----D G-LPMLND-----EEASGAETT-SGVPD---LDSLTP----TFSAMC------PFGCHCH L----RVVQCSDLG----LKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLSRVPSG-LPDLKLLQVV YLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_004065120.1 biglycan [Gorilla gorilla gorilla] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MWP-------------- --------------------------------------LWLLVSLLALSQAL-------- -----------------------------------------PFEQRGFWDFTLD-----D G-PFLMND-----EEASGAD-T-SGVLD---PDSVTP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLARVPSG-LPDLKLLQVV YLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_017900688.1 PREDICTED: biglycan [Capra hircus] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MWP-------------- --------------------------------------LWPLAALLALSQAL-------- -----------------------------------------PFEQKAFWDFTLD-----D G-LPMLND-----EEASGAETT-SGIPD---LDSLPP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLSRVPAG-LPDLKLLQVV YLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPFP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_006032095.1 biglycan [Alligator sinensis] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MVP-------------- ---------------------------------LLLLALLYPTGALGLGLVP-------- -----------------------------------------PFEQHGFLDFSLD-----D TPALGPGDE----DEASGLFPT-SGAPDLGLDELGLP----PPSGHC------PFGCHCH L----RVVQCSDLG----LKEVPKDLPPDTTLLDLQNNFISELRADAFKGLEHLYALVLV NNRLSR--VDPKAWTPLRR-LQKLYLSRNLLTRVPAPLPPALVELRI------------- --------------HDNKIRR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKAVFHGLRQMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------QLNYLRISEAQLTGVPKDLP--- -ETLTELHLDHNQIQAIELEDLKRYSKLT------------------------------- --------RLGLGHNRVR--GVENGSLSFLPLLRDLHLEHNKLQRVPPG-LPNLRHLQVV YLHANNISAVGPHDFCPPGFGVKRSPYHGISLFGNPLP----------------AWE--- ---------------VPPAA---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VSAPLAVQ-----------------------FG NYRK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_006269090.1 PREDICTED: biglycan [Alligator mississippiensis] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MVP-------------- ---------------------------------LLLLVLLCPTGALGLGLVP-------- -----------------------------------------PFEQHGFLDFSLD-----D VPALGPGDE----DEASGLFPT-SGAPDLGLDELGLP----PPSGHC------PFGCHCH L----RVVQCSDLG----LKEVPKDLPPDTTLLDLQNNFISELRADAFKGLEHLYALVLV NNRLSR--VDPKAWTPLRR-LQKLYLSRNLLTRVPAPLPPALVELRI------------- --------------HDNKIRR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKAVFHGLHQMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------QLNYLRISEAQLTGVPKDLP--- -ETLTELHLDHNQIQAIELEDLKRYSKLT------------------------------- --------RLGLGHNRVR--GVENGSLSFLPLLRELHLEHNKLQRVPPG-LPNLRHLQVV YLHANNISAVGPHDFCPPGFGVKRSPYHGISLFGNPLP----------------AWE--- ---------------VPPAA---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VSAPLAVQ-----------------------FG NYRK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_015797476.1 PREDICTED: biglycan [Nothobranchius furzeri] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MC------PFGCHCQ L----RVVQCSDLG----LTEVPKNIPSDTKFLDLQNNRITELKENDFRGLTNLYALSVR NNKISK--VHPKTFAPLKR-MQKLYFSKNLMSTIPKNLPASLVELRI------------- --------------HENRIKK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VAAGAFSGLGNMNCIEMGANPIQNS-----------------------GFEPG AFKGL--------------------------------RLNFLRISDAKLTGVPKDLP--- -DSLHELHLDHNQIQAVELEDLSRYKNLY------------------------------- --------RLGLGFNHIR--NIEQSSLLYLPRLRELHLDNNRLTHVPQD-LPNMKYLQVV YLHSNNISQVGVDDFCPRGFGMKKAFYNGISLFENPVN----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VGDRFAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_020741083.1 biglycan [Odocoileus virginianus texanus] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MWP-------------- --------------------------------------LWPLAALLALSQAL-------- -----------------------------------------PFEQKAFWDFTLD-----D G-LPMLND-----EEASGAETT-SGIPD---LDSLPP----TYSAMC------PFGCHCH L----RVVQCSDLG----LKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLV NNKISK--IHEKAFSPLRK-LQKLYISKNHLVEIPPNLPSSLVELRI------------- --------------HDNRIRK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------VPKGVFSGLRNMNCIEMGGNPLENS-----------------------GFEPG AFDGL--------------------------------KLNYLRISEAKLTGIPKDLP--- -ETLNELHLDHNKIQAIELEDLLRYSKLY------------------------------- --------RLGLGHNQIR--MIENGSLSFLPTLRELHLDNNKLSRVPAG-LPDLKLLQVV YLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYKK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------- >XP_040178826.1 biglycan [Rana temporaria] ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MKV-------------- --------------------------------------LLLICTSVLLCNAL-------- -----------------------------------------PFEQRGFWDFSMD-----D G-LTMMRDEA--NEEGSGFSTATPGKKG---PTAFPPH--MPPMDLC------PFGCQCH L----RVVQCSDLG----LTSVPKNIPKDTMLLDLQNNKIMEIKKDDLKGLSKLYALVLV NNKISK--VNEKAFEPCSN-LQKLYISKNSLEEIPKSLPKSLVELRI------------- --------------HENKIKK--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------IPKDVFNGLKNMNCIELGGNPLENG-----------------------GIDAG AFNGL--------------------------------KLNYLRISEAKLSGIPKGLP--- -ASLNELHLDHNRIQAVEMGDLSTLPNLY------------------------------- --------RLGLGYNIIR--QVENGSLSSLPILRELHLDNNKLAKVPPG-LPDLKFLQVV YLHSNNITQVGVNDFCPTGFGVKRAYYNGISLFNNPVP----------------YWE--- ---------------VQPAT---------------------------------------- -------------------------------------FRC-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------VTDRLAIQ-----------------------FG NYRK-------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------
BMGE Cleaned alignment of selected proteins >NP_001702.1 biglycan preproprotein [Homo sapiens] LWRLVSLLALSQALPFEQRGFWDFTLDPFMMNDEEASGAD-TSGVLDPDSVTPPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >CAE1318869.1 SLIT2 [Sepia pharaonis] TLTTALLCWLFHQRPFGRRRSGILMIWLLGTSTNLGSRLHNG-----------PQRCACIGVSVDCSFRGLKTVPSDIPPETERLDLKGNNITHIRRTDFTGLRSIRVLQLPENRITKIERGAFQDLISMERL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- >XP_039261916.1 podocan-like [Styela clava] LLFNPLCTTLWKLMPISSVGMTTKMMT------NNTSELHEN-----------PVMCRCPTETVDCSQAKLTDIPHDISQKAINLLLNGNRLSEISDECFSMCPRIQTLNLKGNEISEISKNAFYALSNLHHLYLSQNKLQKIPKDLPNSIISLNLHNNNITSISSGIFRKKKKLIALYLQNNNLINEGLSSKSFTGLRLEYLDLSNNELKEIPENIPKNIRRLHLEKNHLEKITHKSLAALQKLEYLLLQYNNLNSIDPGSFSKLRSLKTLHIFTNNLETVPSFLP--PRLEYLILLSNGIKKLKRNTF------AGARQIRDLNMRYNKITLEKGALPRLTTIDSGNQLT >XP_006561501.1 protein slit isoform X1 [Apis mellifera] MLNNNKLTTLGKEMPIHLKDRNIADVQ------KCSGPVERT---G-------PHPCRCADGIVDCRENSLTKVPTHLPEDTTELRLEQNRITEIPPKAFSPYRKLRRIDLSNNQIKKVAADAFHGLKSLESLVLYGNKITELPSGLFQGLTNLQLYDNNIRSVMQGSFDGLTHIRTINMQGNPLSCNCHDPPRLKDAAGSVVRCSRSQLTEIPRGIPPETTELYLDVNDIKTIQPERLNHLRILTRLDLSNNQIGMLSNDTFRNLTKLSHLIISYNKLQCVQRNLAGLKSLRIMSLHGNDISVIPEGAF------EDLQSITHLALGSNPLYTTPATNGDHIAVEVGNYPT >XP_038070682.1 slit homolog 2 protein-like [Patiria miniata] ALSNNNLTTLSSSSPRQFRGLKVPELQ------RCTGEEDHE-----------PAGCTCNSNVVDCRGIGLTELPRTFPDRAVELRLEQNQIRSIPSRAFTQYKKLKRIDLSNNMIETIADDAFVGLRALSSLVLYGNQINDLPEGIFRGLTSLQLYDNQIMSITSGAFDSLKELSTVNLMGNPLNCNCQSPDNLRDVSGSVVRCSRKELTMPPRNIPLTATEIYLDSNQLVTI-PEGMTNLKSLHTLDLSTNLITMLPENAFANMTKLSTLILSYNRIACIPPGFTGLRSLRILSLQGNDLSTLPNGVF------SDLHSLSHIALGNNPLYTAPSKTMDHLAVEAGNFPA >XP_030837166.1 relaxin receptor 2-like [Strongylocentrotus purpuratus] IIGSGSCQWANDLIPCGNSTECVAQQFAHCQNAESGCAIADGLAHFDYVHPVSPDGCVCSKTQLDCSEFNLNEVPPNLPENITRLYLKSNNIVNIGSELLANYSSLVYLNLMGNRIHEIAENSFRNLRNLKRLFLSENNISR---------------------IQTGAFNGLSGLHWLFLNDNKMR--TLEPGIFLGLGLYWLDMRNNEIRDLQEGEAKSLVWLDFEGNDIRSINARSFAGNTSLTVLILRNNSIESIERDAFTSLGTLVELDLSHNQISHLPEGFDGLHTLEILRLRNNPLFSLPVDVF------RGMKKLVDLDLAEIIIGLEKVAIKTRRAIMFGNFYG >ADT80787.1 decorin [Cervus nippon] FLL---VAQVSWAGPFQQKGLFDFMLE------DEASGIGPD----DRFHEVPPFRCQCHLRVVQCSDLGLEAVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHENEITKVRKSVFNGLNQMIVVELGTNPRKSSGIENGAFQGMKLSYIRIADTNITTIPQGLPPSLTELHLDGNKITKVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKLVKVPGGLADHKYIQVVYLHNNNISVIGSNDFCPPGYNTKKASYSGVSLFSNPVQIQPSTVYVRAAVQLGNYK- >KAB0341533.1 hypothetical protein FD754_018459 [Muntiacus muntjak] LWPLAALLALSQALPFEQRAFWDFTLDLPMLNDEEASGAETTSGIPDLDSLPPPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >KAB0372067.1 hypothetical protein FD755_015859 [Muntiacus reevesi] LWPLAALLALSQALPFEQKAFWDFTLDLPMLNDEEASGAETTSGIPDLDSLPPPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPMLRELHLDNNKLSRVPSGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >NP_510426.1 Uncharacterized protein CELE_C44H4.3 [Caenorhabditis elegans] VL------------P--------------------------------------QTACSCDSPVIKCSGHDVEKLSTTTTMEVRELALENADIIEVGPKAFKTL-RIKKLILSNNRIEKIHDHAFTGLENMQELSLSENNLKEVPTSALAGLRVLNIKCNKIENITTKAFVNMTSLIDVNLGCNQICSMAADTFANVKMSLQNLILDNNCMTEFPSKAVNNLIALHIKYNKINAIRQNDFVNLTSLSMLSLNGNNISEIKGGALQNTPNLHYLYLNENNLQTLDNGLEQFKQLQVLDLSFNNFTDITKEMF------EGLESIQHLNLDSNRISVAPGAETTETTEKVGKSKK >OWJ99220.1 BGN [Cervus elaphus hippelaphus] LWPLAALLALSQALPFEQKAFWDFTLDLPMLNDEEASGAETTSGIPDLDSLPPPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >XP_041429161.1 biglycan [Xenopus laevis] LLLLCSCILVIHALPFEQRGFWDFSMDMAMMKDEEASGVGPI-----PTESIPPFGCQCHLRVVQCSDLGLTSIPKNLPKDTTLLDLQNNKITEIKKDDFKGLTNLYALVIVNNKISKINEKAFEPLQKMQKLYISKNNLEEIPKNLPKSLVELRIHENKIKKVPKGVFSGLKNMNCIEMGGNPLENGGIEAGAFDGLKLNYLRVSEAKLSGIPKGLPSTLNELHLDNNKIQAIEKEDLSQYASLYRLGLGHNNIRMIENGSLSFMPVLRELHLDNNKLSKVPPGLPDMKLLQVVYLHSNNITQVGVNDFCPIGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYRK >XP_003210079.1 asporin [Meleagris gallopavo] LL----FLALCSAKPLIGPSY--FTLKLQDMEEDDDNSLFPT-----TEPIIPPFGCQCYVRVVHCSDLGLTSIPRNIPPDTRMIDLQNNKIREVKENDLQGLTTLYALALNNNKITKIHPKAFQPTKKLRRLYLSHNQLTEIPTNLPKTLAELRIHANKVKKIPKDAFKGMKSLHVLEMSANPLNNDGIEPGAFEGVNIYHIRIAEAKLTSIPKDLPSTLLELHLDDNKITAVELEDFNRYKDLQRLGLGNNKIKDVENGSFANIPSIREIHLEKNKLKKVPPGLPDLKYLQVVFLHSNHIAKLGVNDFCPTGRRKKKALYSGISLFNNPVKVQPSTILARNSVQLGNFLE >XP_043309693.1 asporin [Cervus canadensis] LV----FLTLCSAKPLFHPSY--MTLKLKDMEDDADNSLFPT-----REPVNPPFGCQCYSRVVHCSDLGLSSVPSNIPFDTRLVDLQNNKIKEIKENDFKGLTSLYALILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHDNKVKKIQKETFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSIPKDLPSTLLELHLDYNKISVVELEDFKRYKDLQRLGLGNNRITDIENGSLANIPRVREIHLENNKLKKVPSGLQELKYLQIIFLHSNSITKVGVNDFCPTVPKMKKSLYSAISLSNNPVKVQPATVLSRMSVQLGNFRK >XP_040537973.1 asporin [Gallus gallus] LL----FLALCSAKPLIGPSY--FTLKLQDMEEDDDNSLFPT-----TEPIISPFGCQCYVRVVHCSDLGLTSIPRNIPPDTRMIDLQNNKIREVKENDLQGLASLYALALNNNKITKIHPKAFQPTKNLRRLYLSHNQLTEIPTNLPKTLAELRIHANKVKKIPKDAFKGMKSLHVLEMSANPLNNDGIEPGAFEGVNIYHIRIAEAKLTSIPKDLPSSLLELHLDDNKITAVELEDFNRYKDLQRLGLGNNKIKDVENGSFANIPSIREIHLEKNKLKKVPPGLPDLRYLQVVFLHSNHIAKLGVNDFCPTGRRKKKALYSGISLFNNPVKVQPSTILARNSVQLGNFLK >XP_005508936.1 asporin [Columba livia] LL----FLALCSAKPLIGPSY--FTLKVQDMEEDDDNSLFPT-----TEPMIPPFGCQCYVRVVHCSDLGLTSIPRYIPPDTRMIDLQNNKIKEVKEKDLQGLTSLYALALNNNKITKIHPKAFQSTQKLRRLYLSHNQLTEIPTNLPKTLAELRIHANKVKKIHKDVFKGMKSLHVLEMSANPLDNDGIEPGAFEGVNIYHIRIAEAKLTSIPKDLPSSLLELHLDDNKITAIELEDFNRYKDLQRLGLGNNKIKDVENGSFANIPSIREIHLEKNKLKKVPPGLPELKYLQVVFLHSNHIAKLGVNDFCPTGRRKKKALYSGISLFNNPVKVEPSTILARNSVQLGNFLK >KAF4019508.1 hypothetical protein G4228_011300 [Cervus hanglu yarkandensis] LV----FLTLCSAKPLFHPSY--MTLKLKDMEDDADNSLFPT-----REPVNPPFGCQCYSRVVHCSD-------------------------------------------------------------------------------------------------------------LEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSIPKDLPSTLLELHLDYNKISVVELEDFKRYKDLQRLGLGNNRITDIENGSLANIPRVREIHLENNKLKKVPSGLQELKYLQIIFLHSNSITKVGVNDFCPTVPKMKKSLYSAISLSNNPVKVQPATVLSRMSVQLGNFRK >XP_004070537.1 biglycan [Oryzias latipes] LLCLFQLHAPSSALPFEQRGFWDFSLDMAMMNDEEGSAMEPT---------PSPFGCHCQRKVVQCSDLGLTEVPRNIPPDTRFLDLQNNQISELRENDFKGLTDLYALSVRNNIISKVHPRAFVPLKRMQKLYFSKNLLSTIPKNLPASLIELRIHENRIRKVGAGSFSGLTNMNCIEMGANPIQNSGFEPGAFKGLRLNFLRLSEAKLTGVPKDLPDSLHELHLDHNQIQAVELEDLSRYKNLYRLGLGFNNIRNIENGSLSYLPMLRELHLENNRLTRIPQGLPSMKYLQVVYLHSNSINHVDVDDFCPRGFGMKRTFYNGISLFDNPVNVQPATVNDRYAIQFGNYKK >XP_030278617.1 biglycan [Sparus aurata] LLCVVRLLSPSSALPFEQRGFWDFAMDMTMMRDEEGSAVEEI---------LPPFGCHCQLRVVQCSDLGLTEVPKNIPRDTKFLDLQNNRITELKENDFAGLTNLYGLSLRNNHISKVHPRAFVPLKHMQKLYFSKNFLTTIPKNLPASLVEMRIHENRIKKVAAGAFSGLSNMNCIEMGANPIQNSGFEPGAFKGLKLNFLRISEAKLTGVPKDLPESLHELHLDHNEIQAVELEDLSRYKNLYRLGLGYNHIRNIENGSLSYLPRLRELHLENNRLTRVPRGLPDMKYLQVVYLHSNNIDQVGVDDFCPRGFGMKRAFYNGISLFANPVNVQPATVSDRLAIQFGNYKK >NP_031568.2 biglycan preproprotein [Mus musculus] LWLLTLLLALSQALPFEQKGFWDFTLDLLMMNDEEASGSDTTSGVPDLDSVTPPFGCHCHLRVVQCSDLGLKTVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHSNNITKVGINDFCPMGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >NP_058783.1 biglycan precursor [Rattus norvegicus] LWLLTLLLALSQALPFEQKGFWDFTLDLLMMNDEEASGSDTTSGVPDLDSLTPPFGCHCHLRVVQCSDLGLKTVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHSNNITKVGINDFCPMGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >NP_847888.2 biglycan precursor [Bos taurus] LWPLAALLALSQALPFEQKAFWDFTLDLPMLNDEEASGAETTSGIPDLDSLPPPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >XP_013841982.2 biglycan isoform X1 [Sus scrofa] LWLLASLLALSQALPFEQKAFWDFTLDLPMLNDEEASGADSTSGIPDLDALPPPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHAKAFSPLRKLQKLYISKNHLVEIPPNLPSSLAELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >XP_038304748.1 biglycan isoform X1 [Canis lupus familiaris] LWLVASLLALTQALPFEQKGFWDFTLDLPMLNDEEASGAETTSGVPDLDALTPPFGCHCHLRVVQCSDLGLKAVPKEISPDTMLLDLQNNDISELRADDFKGLHHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPSGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >NP_001009201.1 biglycan precursor [Ovis aries] LWLLAALLALSQALPFEQKAFWDFTLDLPMLNDEEASGAETTSGIPDLDSLPPPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >XP_016799988.1 biglycan [Pan troglodytes] LWRLVSLLALSQALPFEQRGFWDFTLDPFMMNDEEASGAD-TSGVLDPDSVTPPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >NP_001001825.2 biglycan b precursor [Danio rerio] LLSVCSLTAPSMALPFEQRGFWDFAMDTVMMRDEEGSASEEL----------PPFGCHCQVNIVQCSDLSLIAVPKEIPRDTKLLDLQNNCITELKENDFKGLTNLYALSLVNNKISKVHPRVFTPLRHLKKLYFSHNLLTVVPKNLPPSLVELRIHDNRIKKVAEGTFSGLGSMNCIEMGGNPIQNSGFEPGAFKGLKLNYLRVSEAKLTGIPKDLPDSLHELHLDNNQIQAIELEDLRRYKHLYRLGLGFNQIRMIENGSLSYVSNLRELHLENNRLTRVPKGLPDMKYLQVAYLHSNNISQVDVNDFCPQGFGMKRNFYHGISLYGNPVNVQPATVADRLAIQFGNYKK >tr|Q6GMI5|Q6GMI5_DANRE Biglycan OS=Danio rerio OX=7955 GN=bgna PE=2 SV=1 FLCTAHLPIYSSALPFEQKGFWDFGKDMMMMDQEEGSAVEPY-----------PFGCRCELRVVQCSDLGLGYVPYDIPADTLLLDLQSNRITEIREGDFKGLSNLYALVLRYNQISKIHPKAFLPLKRLQKLYISHNLLTSMPKNLPSSLVELRIHDNRIKKVPAFSFSGLHNMHVIEMGRNPLQNSGFEPGAFMGLKLNYLRISEAKLTGVPKDLPGSLHELHLDNNQIQAIELVDLSQYTQLQRLGLGSNQIRHIEHGALSYLTNLRELHLDNNRLPSVPSGLSHMKYLQVVYLHSNNITNVGEDDFCPTGFGLKKVFYNGISLFDNPIRVQPSTVSDQMAVQFGNHKK >XP_008248493.1 PREDICTED: biglycan isoform X1 [Oryctolagus cuniculus] LWLLAALLALGQALPFEQKGFWDFALDLLMMNDEEASGAESTSGVPDLDALTPPFGCHCHLRVVQCSDLGLKTVPKEVSPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKITKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >NP_001125588.1 biglycan precursor [Pongo abelii] LWRLVSLLALSQALPFEQRGFWDFTLDPFMMNDEEASGAD-TSGVLDPDSVTPPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLGHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLAGVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >XP_003804899.2 biglycan [Pan paniscus] LWRLVSLLALSQALPFEQRGFWDFTLDPFMMNDEEASGAD-TSGVLDPDSVTPPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHKKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >XP_004001049.2 biglycan [Felis catus] LWLLASLLALSQALPFEQKGFWDFTLDLPMLNDEEASGAETTSGVPDLDSLTPPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPSGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >XP_004065120.1 biglycan [Gorilla gorilla gorilla] LWLLVSLLALSQALPFEQRGFWDFTLDPFLMNDEEASGAD-TSGVLDPDSVTPPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >XP_017900688.1 PREDICTED: biglycan [Capra hircus] LWPLAALLALSQALPFEQKAFWDFTLDLPMLNDEEASGAETTSGIPDLDSLPPPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPFPVQPATVTDRLAIQFGNYKK >XP_006032095.1 biglycan [Alligator sinensis] LLYPTGALGLGLVPPFEQHGFLDFSLDALGPGDDEASGLFPTSGAPDDELGLPPFGCHCHLRVVQCSDLGLKEVPKDLPPDTTLLDLQNNFISELRADAFKGLEHLYALVLVNNRLSRVDPKAWTPLRRLQKLYLSRNLLTRVPAPLPPALVELRIHDNKIRRVPKAVFHGLRQMNCIEMGGNPLENSGFEPGAFDGLQLNYLRISEAQLTGVPKDLPETLTELHLDHNQIQAIELEDLKRYSKLTRLGLGHNRVRGVENGSLSFLPLLRDLHLEHNKLQRVPPGLPNLRHLQVVYLHANNISAVGPHDFCPPGFGVKRSPYHGISLFGNPLPVPPAAVSAPLAVQFGNYRK >XP_006269090.1 PREDICTED: biglycan [Alligator mississippiensis] LLCPTGALGLGLVPPFEQHGFLDFSLDALGPGDDEASGLFPTSGAPDDELGLPPFGCHCHLRVVQCSDLGLKEVPKDLPPDTTLLDLQNNFISELRADAFKGLEHLYALVLVNNRLSRVDPKAWTPLRRLQKLYLSRNLLTRVPAPLPPALVELRIHDNKIRRVPKAVFHGLHQMNCIEMGGNPLENSGFEPGAFDGLQLNYLRISEAQLTGVPKDLPETLTELHLDHNQIQAIELEDLKRYSKLTRLGLGHNRVRGVENGSLSFLPLLRELHLEHNKLQRVPPGLPNLRHLQVVYLHANNISAVGPHDFCPPGFGVKRSPYHGISLFGNPLPVPPAAVSAPLAVQFGNYRK >XP_015797476.1 PREDICTED: biglycan [Nothobranchius furzeri] -----------------------------------------------------PFGCHCQLRVVQCSDLGLTEVPKNIPSDTKFLDLQNNRITELKENDFRGLTNLYALSVRNNKISKVHPKTFAPLKRMQKLYFSKNLMSTIPKNLPASLVELRIHENRIKKVAAGAFSGLGNMNCIEMGANPIQNSGFEPGAFKGLRLNFLRISDAKLTGVPKDLPDSLHELHLDHNQIQAVELEDLSRYKNLYRLGLGFNHIRNIEQSSLLYLPRLRELHLDNNRLTHVPQDLPNMKYLQVVYLHSNNISQVGVDDFCPRGFGMKKAFYNGISLFENPVNVQPATVGDRFAIQFGNYKK >XP_020741083.1 biglycan [Odocoileus virginianus texanus] LWPLAALLALSQALPFEQKAFWDFTLDLPMLNDEEASGAETTSGIPDLDSLPPPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYKK >XP_040178826.1 biglycan [Rana temporaria] LLLICTSVLLCNALPFEQRGFWDFSMDLTMMRDEEGSGFSTAPGKKGPTAFPPPFGCQCHLRVVQCSDLGLTSVPKNIPKDTMLLDLQNNKIMEIKKDDLKGLSKLYALVLVNNKISKVNEKAFEPCSNLQKLYISKNSLEEIPKSLPKSLVELRIHENKIKKIPKDVFNGLKNMNCIELGGNPLENGGIDAGAFNGLKLNYLRISEAKLSGIPKGLPASLNELHLDHNRIQAVEMGDLSTLPNLYRLGLGYNIIRQVENGSLSSLPILRELHLDNNKLAKVPPGLPDLKFLQVVYLHSNNITQVGVNDFCPTGFGVKRAYYNGISLFNNPVPVQPATVTDRLAIQFGNYRK
PhyML tree of selected proteins (ADT80787_1_decorin__Cervus_nippon_:0.48624479,(((XP_005508936_1_asporin__Columba_livia_:0.03503388,(XP_003210079_1_asporin__Meleagris_gallopavo_:0.00921025,XP_040537973_1_asporin__Gallus_gallus_:0.01379633):0.00914789):0.11038611,(KAF4019508_1_hypothetical_protein_G4228_011300__Cervus_hanglu_yarkandensis_:0.00000001,XP_043309693_1_asporin__Cervus_canadensis_:0.00000001):0.18305492):0.44185512,(((((XP_004065120_1_biglycan__Gorilla_gorilla_gorilla_:0.0031352,(NP_001702_1_biglycan_preproprotein__Homo_sapiens_:0.00315325,(NP_001125588_1_biglycan_precursor__Pongo_abelii_:0.00628942,(XP_003804899_2_biglycan__Pan_paniscus_:0.00313395,XP_016799988_1_biglycan__Pan_troglodytes_:0.00000001):0.00000001):0.00000001):0.00315373):0.01790809,((XP_008248493_1_PREDICTED__biglycan_isoform_X1__Oryctolagus_cuniculus_:0.0220451,(NP_031568_2_biglycan_preproprotein__Mus_musculus_:0.00313024,NP_058783_1_biglycan_precursor__Rattus_norvegicus_:0.00000001):0.01857814):0.00757963,(XP_004001049_2_biglycan__Felis_catus_:0.00000001,(XP_038304748_1_biglycan_isoform_X1__Canis_lupus_familiaris_:0.01927851,(XP_013841982_2_biglycan_isoform_X1__Sus_scrofa_:0.01593774,(NP_001009201_1_biglycan_precursor__Ovis_aries_:0.00000001,((NP_847888_2_biglycan_precursor__Bos_taurus_:0.00000001,(OWJ99220_1_BGN__Cervus_elaphus_hippelaphus_:0.00000001,XP_020741083_1_biglycan__Odocoileus_virginianus_texanus_:0.00000001):0.00000001):0.00000001,(KAB0341533_1_hypothetical_protein_FD754_018459__Muntiacus_muntjak_:0.00316329,(KAB0372067_1_hypothetical_protein_FD755_015859__Muntiacus_reevesi_:0.00633597,XP_017900688_1_PREDICTED__biglycan__Capra_hircus_:0.00316891):0.00000001):0.00000001):0.00316518):0.00314695):0.01296565):0.00308301):0.01039405):0.01080897):0.06915078,(XP_006032095_1_biglycan__Alligator_sinensis_:0.00616902,XP_006269090_1_PREDICTED__biglycan__Alligator_mississippiensis_:0.00415189):0.42101374):0.06221679,(tr_Q6GMI5_Q6GMI5_DANRE_Biglycan_OS_Danio_rerio_OX_7955_GN_bgna_PE_2_SV_1:0.30483446,(NP_001001825_2_biglycan_b_precursor__Danio_rerio_:0.17237952,(XP_030278617_1_biglycan__Sparus_aurata_:0.05313811,(XP_004070537_1_biglycan__Oryzias_latipes_:0.13315661,XP_015797476_1_PREDICTED__biglycan__Nothobranchius_furzeri_:0.07216245):0.03112794):0.05930719):0.07869575):0.14314648):0.05338697,(XP_041429161_1_biglycan__Xenopus_laevis_:0.07327644,XP_040178826_1_biglycan__Rana_temporaria_:0.1743713):0.08665739):0.1506637):0.18687355,(CAE1318869_1_SLIT2__Sepia_pharaonis_:1.38718296,((XP_006561501_1_protein_slit_isoform_X1__Apis_mellifera_:0.26044605,XP_038070682_1_slit_homolog_2_protein_like__Patiria_miniata_:0.71688574):1.44431173,(NP_510426_1_Uncharacterized_protein_CELE_C44H4_3__Caenorhabditis_elegans_:2.27949433,(XP_039261916_1_podocan_like__Styela_clava_:1.34773069,XP_030837166_1_relaxin_receptor_2_like__Strongylocentrotus_purpuratus_:1.8634112):0.57537774):0.24508453):0.25709403):0.6409032);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)