|Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.
GO:0003254 (involved in) regulation of membrane depolarization
GO:0019731 (involved in) antibacterial humoral response
GO:0045087 (involved in) innate immune response
GO:0050829 (involved in) defense response to Gram-negative bacterium
GO:0050830 (involved in) defense response to Gram-positive bacterium
GO:0061844 (involved in) antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0071222 (involved in) cellular response to lipopolysaccharide
|Open source database system and analysis tools for molecular interaction data.
|An open access resource for human proteins
|InterPro (new pfam)
|InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.