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PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0001 | P02765 | Alpha-2-HS-glycoprotein | AHSG | A2HS, AHS, APMR1, FETUA, HSGA | Homo_sapiens | Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. |
Domains | Gene Ontology |
PF00031 (Cystatin) |
GO:0004866 (enables) endopeptidase inhibitor activity
GO:0004869 (enables) cysteine-type endopeptidase inhibitor activity GO:0019210 (enables) kinase inhibitor activity GO:0001501 (involved in) skeletal system development GO:0001503 (involved in) ossification GO:0006907 (involved in) pinocytosis GO:0006953 (involved in) acute-phase response GO:0010951 (involved in) negative regulation of endopeptidase activity GO:0030500 (involved in) regulation of bone mineralization GO:0030502 (involved in) negative regulation of bone mineralization GO:0046627 (involved in) negative regulation of insulin receptor signaling pathway GO:0050727 (involved in) regulation of inflammatory response GO:0050766 (involved in) positive regulation of phagocytosis GO:0031012 (is active in) extracellular matrix GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005788 (located in) endoplasmic reticulum lumen GO:0005794 (located in) Golgi apparatus GO:0031093 (located in) platelet alpha granule lumen GO:0034774 (located in) secretory granule lumen GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome GO:0072562 (located in) blood microparticle |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |